IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Upf3a

UPF3 regulator of nonsense transcripts homolog A (yeast)

RGD: 1308778
Ensembl: ENSRNOG00000017397
Entrez: 361176
UniProtKB: Q5I0C8

Process Predictions
Disease Predictions

Upf3a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
intracellular signal transduction	GO:0035556	314	0.062
regulation of molecular function	GO:0065009	398	0.056
regulation of catalytic activity	GO:0050790	304	0.055
regulation of phosphate metabolic process	GO:0019220	349	0.051
regulation of apoptotic process	GO:0042981	335	0.050
regulation of phosphorus metabolic process	GO:0051174	349	0.048
nucleic acid templated transcription	GO:0097659	379	0.047
positive regulation of phosphorus metabolic process	GO:0010562	262	0.047
regulation of signal transduction	GO:0009966	318	0.044
regulation of intracellular signal transduction	GO:1902531	218	0.044
positive regulation of catalytic activity	GO:0043085	184	0.044
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.039
negative regulation of rna biosynthetic process	GO:1902679	118	0.039
positive regulation of cell communication	GO:0010647	271	0.039
regulation of cellular protein metabolic process	GO:0032268	267	0.039
positive regulation of phosphate metabolic process	GO:0045937	262	0.038
cell cell signaling	GO:0007267	335	0.037
programmed cell death	GO:0012501	392	0.037
rna biosynthetic process	GO:0032774	380	0.037
neuron differentiation	GO:0030182	368	0.037
aromatic compound catabolic process	GO:0019439	168	0.036
regulation of cell differentiation	GO:0045595	320	0.036
positive regulation of programmed cell death	GO:0043068	157	0.036
positive regulation of cellular protein metabolic process	GO:0032270	167	0.036
regulation of nucleic acid templated transcription	GO:1903506	380	0.035
protein phosphorylation	GO:0006468	345	0.035
cell projection organization	GO:0030030	302	0.035
regulation of rna metabolic process	GO:0051252	391	0.034
cellular response to stress	GO:0033554	269	0.034
carbohydrate derivative metabolic process	GO:1901135	346	0.033
negative regulation of gene expression	GO:0010629	199	0.032
nucleobase containing small molecule metabolic process	GO:0055086	316	0.031
reproductive process	GO:0022414	372	0.031
nucleoside metabolic process	GO:0009116	179	0.031
ribonucleotide metabolic process	GO:0009259	231	0.031
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.030
ribose phosphate metabolic process	GO:0019693	235	0.030
transcription dna templated	GO:0006351	377	0.030
organic substance catabolic process	GO:1901575	316	0.029
purine ribonucleotide metabolic process	GO:0009150	227	0.029
negative regulation of cell communication	GO:0010648	158	0.029
positive regulation of cellular biosynthetic process	GO:0031328	295	0.029
regulation of protein metabolic process	GO:0051246	289	0.029
nucleoside phosphate catabolic process	GO:1901292	140	0.028
transcription from rna polymerase ii promoter	GO:0006366	252	0.028
positive regulation of molecular function	GO:0044093	230	0.028
regulation of rna biosynthetic process	GO:2001141	381	0.028
purine ribonucleotide catabolic process	GO:0009154	136	0.028
positive regulation of protein metabolic process	GO:0051247	178	0.028
cellular response to endogenous stimulus	GO:0071495	377	0.028
nucleotide metabolic process	GO:0009117	279	0.027
organophosphate metabolic process	GO:0019637	370	0.027
regulation of multicellular organismal development	GO:2000026	376	0.027
negative regulation of macromolecule metabolic process	GO:0010605	260	0.027
glycosyl compound metabolic process	GO:1901657	182	0.027
purine nucleotide metabolic process	GO:0006163	229	0.026
regulation of cell proliferation	GO:0042127	359	0.026
regulation of programmed cell death	GO:0043067	341	0.026
cellular catabolic process	GO:0044248	295	0.026
apoptotic process	GO:0006915	381	0.026
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.026
positive regulation of response to stimulus	GO:0048584	285	0.026
regulation of cellular component organization	GO:0051128	368	0.025
regulation of phosphorylation	GO:0042325	248	0.025
nucleoside catabolic process	GO:0009164	126	0.025
response to growth factor	GO:0070848	189	0.025
positive regulation of biosynthetic process	GO:0009891	319	0.025
cellular response to growth factor stimulus	GO:0071363	162	0.025
positive regulation of cell death	GO:0010942	184	0.024
negative regulation of biosynthetic process	GO:0009890	168	0.024
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.024
ribonucleoside metabolic process	GO:0009119	174	0.024
regulation of neurogenesis	GO:0050767	247	0.024
nucleoside phosphate metabolic process	GO:0006753	283	0.024
small gtpase mediated signal transduction	GO:0007264	36	0.024
rna metabolic process	GO:0016070	406	0.024
nucleobase containing compound catabolic process	GO:0034655	152	0.023
single organism reproductive process	GO:0044702	297	0.023
cellular nitrogen compound catabolic process	GO:0044270	163	0.023
reproduction	GO:0000003	245	0.023
cell morphogenesis involved in differentiation	GO:0000904	119	0.023
ras protein signal transduction	GO:0007265	29	0.022
purine containing compound catabolic process	GO:0072523	138	0.022
localization of cell	GO:0051674	202	0.022
cellular component movement	GO:0006928	248	0.022
negative regulation of signaling	GO:0023057	157	0.022
multicellular organism reproduction	GO:0032504	233	0.022
nucleoside triphosphate metabolic process	GO:0009141	144	0.022
anatomical structure morphogenesis	GO:0009653	298	0.022
regulation of transcription dna templated	GO:0006355	374	0.022
purine nucleoside catabolic process	GO:0006152	124	0.022
positive regulation of protein modification process	GO:0031401	142	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.021
neuron development	GO:0048666	286	0.021
positive regulation of apoptotic process	GO:0043065	154	0.021
regulation of nervous system development	GO:0051960	264	0.021
cellular amine metabolic process	GO:0044106	38	0.021
regulation of protein modification process	GO:0031399	194	0.021
regulation of transferase activity	GO:0051338	123	0.021
positive regulation of cell differentiation	GO:0045597	217	0.021
positive regulation of signaling	GO:0023056	270	0.021
negative regulation of metabolic process	GO:0009892	331	0.020
regulation of kinase activity	GO:0043549	117	0.020
purine containing compound metabolic process	GO:0072521	253	0.020
multi organism reproductive process	GO:0044703	262	0.020
positive regulation of phosphorylation	GO:0042327	177	0.020
positive regulation of signal transduction	GO:0009967	175	0.020
multicellular organismal reproductive process	GO:0048609	233	0.020
heterocycle catabolic process	GO:0046700	167	0.020
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
ribonucleoside catabolic process	GO:0042454	126	0.019
response to nutrient	GO:0007584	248	0.019
cardiovascular system development	GO:0072358	134	0.019
regulation of cell development	GO:0060284	263	0.019
negative regulation of signal transduction	GO:0009968	83	0.019
sexual reproduction	GO:0019953	148	0.019
regulation of hydrolase activity	GO:0051336	143	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.019
response to oxygen levels	GO:0070482	265	0.019
organic cyclic compound catabolic process	GO:1901361	175	0.019
positive regulation of transcription dna templated	GO:0045893	197	0.019
neuron projection development	GO:0031175	273	0.018
regulation of protein phosphorylation	GO:0001932	183	0.018
cell morphogenesis	GO:0000902	142	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.018
positive regulation of protein phosphorylation	GO:0001934	135	0.018
cellular ketone metabolic process	GO:0042180	51	0.018
purine ribonucleoside metabolic process	GO:0046128	168	0.018
positive regulation of intracellular signal transduction	GO:1902533	138	0.018
purine nucleoside metabolic process	GO:0042278	169	0.018
response to hypoxia	GO:0001666	231	0.018
cellular response to oxygen containing compound	GO:1901701	386	0.018
intracellular transport	GO:0046907	185	0.018
cation transport	GO:0006812	382	0.017
response to inorganic substance	GO:0010035	377	0.017
organonitrogen compound catabolic process	GO:1901565	179	0.017
negative regulation of multicellular organismal process	GO:0051241	203	0.017
single organism catabolic process	GO:0044712	283	0.017
cellular response to cytokine stimulus	GO:0071345	127	0.017
amine metabolic process	GO:0009308	38	0.017
response to nutrient levels	GO:0031667	370	0.017
regulation of protein kinase activity	GO:0045859	105	0.017
purine nucleotide catabolic process	GO:0006195	136	0.017
negative regulation of rna metabolic process	GO:0051253	123	0.017
regulation of neuron differentiation	GO:0045664	208	0.017
macromolecular complex assembly	GO:0065003	273	0.017
response to peptide hormone	GO:0043434	278	0.017
regulation of cellular ketone metabolic process	GO:0010565	27	0.017
purine ribonucleoside catabolic process	GO:0046130	124	0.017
ribonucleotide catabolic process	GO:0009261	136	0.016
central nervous system development	GO:0007417	311	0.016
response to decreased oxygen levels	GO:0036293	237	0.016
organophosphate catabolic process	GO:0046434	148	0.016
positive regulation of protein kinase activity	GO:0045860	73	0.016
response to extracellular stimulus	GO:0009991	380	0.016
negative regulation of transcription dna templated	GO:0045892	116	0.016
positive regulation of gene expression	GO:0010628	244	0.016
gastrulation	GO:0007369	2	0.016
response to radiation	GO:0009314	137	0.016
macromolecular complex subunit organization	GO:0043933	339	0.016
catabolic process	GO:0009056	351	0.016
gamete generation	GO:0007276	124	0.015
proteolysis	GO:0006508	175	0.015
regulation of cellular amine metabolic process	GO:0033238	8	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.015
regeneration	GO:0031099	163	0.015
negative regulation of cellular metabolic process	GO:0031324	281	0.015
chromosome segregation	GO:0007059	2	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
response to external biotic stimulus	GO:0043207	221	0.015
organelle organization	GO:0006996	266	0.015
carbohydrate derivative catabolic process	GO:1901136	147	0.015
negative regulation of response to stimulus	GO:0048585	155	0.015
positive regulation of cellular amine metabolic process	GO:0033240	3	0.015
positive regulation of developmental process	GO:0051094	283	0.015
negative regulation of cellular biosynthetic process	GO:0031327	161	0.015
response to cytokine	GO:0034097	215	0.014
positive regulation of mapk cascade	GO:0043410	92	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.014
response to bacterium	GO:0009617	200	0.014
negative regulation of developmental process	GO:0051093	125	0.014
negative regulation of cell differentiation	GO:0045596	99	0.014
nucleoside triphosphate catabolic process	GO:0009143	123	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.014
synaptic growth at neuromuscular junction	GO:0051124	1	0.014
cellular component biogenesis	GO:0044085	368	0.014
embryonic pattern specification	GO:0009880	1	0.014
homeostatic process	GO:0042592	331	0.013
response to other organism	GO:0051707	220	0.013
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.013
spindle organization	GO:0007051	2	0.013
sex differentiation	GO:0007548	113	0.013
response to lipopolysaccharide	GO:0032496	191	0.013
inorganic cation transmembrane transport	GO:0098662	202	0.013
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.013
mapk cascade	GO:0000165	140	0.013
cell cycle	GO:0007049	101	0.013
cellular response to lipid	GO:0071396	201	0.013
regulation of mapk cascade	GO:0043408	116	0.013
gtp catabolic process	GO:0006184	71	0.013
cellular component assembly	GO:0022607	360	0.013
response to monosaccharide	GO:0034284	159	0.013
positive regulation of rna metabolic process	GO:0051254	203	0.013
glycosyl compound catabolic process	GO:1901658	126	0.013
positive regulation of cell development	GO:0010720	176	0.012
cellular homeostasis	GO:0019725	252	0.012
regulation of growth	GO:0040008	105	0.012
regulation of neuron projection development	GO:0010975	161	0.012
protein complex assembly	GO:0006461	263	0.012
cell migration	GO:0016477	197	0.012
regulation of cellular localization	GO:0060341	263	0.012
metal ion transport	GO:0030001	289	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
cell motility	GO:0048870	202	0.012
positive regulation of nucleotide metabolic process	GO:0045981	91	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
response to metal ion	GO:0010038	253	0.012
regulation of organelle organization	GO:0033043	80	0.012
positive regulation of transferase activity	GO:0051347	81	0.012
transmembrane transport	GO:0055085	412	0.012
single organism intracellular transport	GO:1902582	166	0.012
regulation of cellular catabolic process	GO:0031329	101	0.012
response to reactive oxygen species	GO:0000302	120	0.012
dephosphorylation	GO:0016311	98	0.011
nucleotide catabolic process	GO:0009166	139	0.011
protein complex subunit organization	GO:0071822	302	0.011
regulation of catabolic process	GO:0009894	113	0.011
positive regulation of hydrolase activity	GO:0051345	86	0.011
axis specification	GO:0009798	4	0.011
dna metabolic process	GO:0006259	96	0.011
cellular component morphogenesis	GO:0032989	155	0.011
regulation of nucleotide metabolic process	GO:0006140	117	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.011
positive regulation of nervous system development	GO:0051962	178	0.011
positive regulation of rna biosynthetic process	GO:1902680	197	0.011
positive regulation of catabolic process	GO:0009896	78	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.011
response to tumor necrosis factor	GO:0034612	56	0.011
positive regulation of cellular component organization	GO:0051130	200	0.011
growth	GO:0040007	165	0.011
head development	GO:0060322	247	0.011
protein localization	GO:0008104	191	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011
hematopoietic progenitor cell differentiation	GO:0002244	2	0.010
regulation of cell growth	GO:0001558	85	0.010
secretion by cell	GO:0032940	248	0.010
response to biotic stimulus	GO:0009607	226	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.010
protein autophosphorylation	GO:0046777	66	0.010
positive regulation of kinase activity	GO:0033674	77	0.010
single organism biosynthetic process	GO:0044711	342	0.010
oxoacid metabolic process	GO:0043436	290	0.010
negative regulation of programmed cell death	GO:0043069	183	0.010
negative regulation of transport	GO:0051051	136	0.010
aging	GO:0007568	241	0.010
negative regulation of cellular protein metabolic process	GO:0032269	106	0.010

Upf3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.016
nervous system disease	DOID:863	0.016
sensory system disease	DOID:0050155	0.016
retinal disease	DOID:5679	0.010
eye disease	DOID:5614	0.010
eye and adnexa disease	DOID:1492	0.010

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