IMP: Integrative Multi-species Prediction

Rattus norvegicus

15 known processes

Snx16

sorting nexin 16

Ensembl: ENSRNOG00000009953
RGD: 620295
Entrez: 64088
UniProtKB: P57769

Process Predictions
Disease Predictions

Snx16 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
transmembrane transport	GO:0055085	412	0.051
multicellular organism reproduction	GO:0032504	233	0.050
single organism intracellular transport	GO:1902582	166	0.050
intracellular protein transport	GO:0006886	79	0.046	Human
cellular catabolic process	GO:0044248	295	0.046
organonitrogen compound biosynthetic process	GO:1901566	167	0.044
organophosphate metabolic process	GO:0019637	370	0.043
organic substance catabolic process	GO:1901575	316	0.043
reproductive process	GO:0022414	372	0.043
purine containing compound metabolic process	GO:0072521	253	0.041
programmed cell death	GO:0012501	392	0.038
protein localization	GO:0008104	191	0.038	Human
catabolic process	GO:0009056	351	0.038
cellular macromolecule localization	GO:0070727	122	0.038	Human
nucleoside phosphate metabolic process	GO:0006753	283	0.035
ribose phosphate metabolic process	GO:0019693	235	0.033
multi organism reproductive process	GO:0044703	262	0.033
single organism reproductive process	GO:0044702	297	0.033
regulation of signal transduction	GO:0009966	318	0.033	Fly
reproduction	GO:0000003	245	0.033
response to inorganic substance	GO:0010035	377	0.032
carbohydrate derivative metabolic process	GO:1901135	346	0.031
organophosphate biosynthetic process	GO:0090407	143	0.030
intracellular transport	GO:0046907	185	0.030
establishment of protein localization	GO:0045184	141	0.030	Human
cell motility	GO:0048870	202	0.029
cellular amine metabolic process	GO:0044106	38	0.029
spindle organization	GO:0007051	2	0.028
multicellular organismal reproductive process	GO:0048609	233	0.028
regulation of phosphorylation	GO:0042325	248	0.028
positive regulation of phosphate metabolic process	GO:0045937	262	0.027
amine metabolic process	GO:0009308	38	0.027
sexual reproduction	GO:0019953	148	0.025
regulation of phosphorus metabolic process	GO:0051174	349	0.025
cellular response to stress	GO:0033554	269	0.025
regulation of rna metabolic process	GO:0051252	391	0.024	Fly
protein modification by small protein conjugation	GO:0032446	31	0.024
purine nucleotide metabolic process	GO:0006163	229	0.024
protein refolding	GO:0042026	3	0.024
negative regulation of metabolic process	GO:0009892	331	0.024
vesicle mediated transport	GO:0016192	181	0.024
purine nucleoside metabolic process	GO:0042278	169	0.024
negative regulation of macromolecule metabolic process	GO:0010605	260	0.024
nucleotide metabolic process	GO:0009117	279	0.024
cellular response to oxygen containing compound	GO:1901701	386	0.024
cellular component assembly	GO:0022607	360	0.024	Fly
protein transport	GO:0015031	132	0.023	Human
purine ribonucleotide metabolic process	GO:0009150	227	0.023
apoptotic process	GO:0006915	381	0.023
protein phosphorylation	GO:0006468	345	0.023
intracellular signal transduction	GO:0035556	314	0.022
negative regulation of cellular metabolic process	GO:0031324	281	0.022
positive regulation of cell communication	GO:0010647	271	0.022
negative regulation of programmed cell death	GO:0043069	183	0.022
organelle organization	GO:0006996	266	0.022
regulation of programmed cell death	GO:0043067	341	0.022
localization of cell	GO:0051674	202	0.021
protein oligomerization	GO:0051259	191	0.021
cell cell signaling	GO:0007267	335	0.021	Fly
positive regulation of gene expression	GO:0010628	244	0.020
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.020
regulation of molecular function	GO:0065009	398	0.020
single organism cellular localization	GO:1902580	102	0.020	Human
single organism biosynthetic process	GO:0044711	342	0.019
negative regulation of cell death	GO:0060548	229	0.019
glycosyl compound metabolic process	GO:1901657	182	0.019
cytoplasmic transport	GO:0016482	115	0.018
developmental process involved in reproduction	GO:0003006	159	0.018
regulation of nucleic acid templated transcription	GO:1903506	380	0.018	Fly
regulation of membrane potential	GO:0042391	110	0.018
regulation of phosphate metabolic process	GO:0019220	349	0.018
cellular component biogenesis	GO:0044085	368	0.018	Fly
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.018
nucleobase containing small molecule metabolic process	GO:0055086	316	0.018
cellular response to endogenous stimulus	GO:0071495	377	0.018
regulation of cell differentiation	GO:0045595	320	0.018
gamete generation	GO:0007276	124	0.018
male gamete generation	GO:0048232	99	0.018
organic cyclic compound catabolic process	GO:1901361	175	0.017
aging	GO:0007568	241	0.017
endocytosis	GO:0006897	84	0.017
spermatogenesis	GO:0007283	99	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017
regulation of apoptotic process	GO:0042981	335	0.017
cellular protein localization	GO:0034613	122	0.017	Human
negative regulation of apoptotic process	GO:0043066	181	0.017
proteolysis	GO:0006508	175	0.017
protein targeting	GO:0006605	61	0.017	Human
ras protein signal transduction	GO:0007265	29	0.017
organonitrogen compound catabolic process	GO:1901565	179	0.016
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.016
positive regulation of signaling	GO:0023056	270	0.016
cellular nitrogen compound catabolic process	GO:0044270	163	0.016
nucleoside phosphate biosynthetic process	GO:1901293	102	0.016
synaptic growth at neuromuscular junction	GO:0051124	1	0.016	Fly
macromolecule localization	GO:0033036	252	0.016	Human
nucleoside metabolic process	GO:0009116	179	0.015
small gtpase mediated signal transduction	GO:0007264	36	0.015
locomotion	GO:0040011	237	0.015
protein complex assembly	GO:0006461	263	0.015
protein modification by small protein conjugation or removal	GO:0070647	35	0.015
positive regulation of molecular function	GO:0044093	230	0.015
cellular amino acid metabolic process	GO:0006520	107	0.015
positive regulation of phosphorus metabolic process	GO:0010562	262	0.015
ion transmembrane transport	GO:0034220	365	0.015
carbohydrate derivative catabolic process	GO:1901136	147	0.014
positive regulation of response to stimulus	GO:0048584	285	0.014
regulation of protein metabolic process	GO:0051246	289	0.014
regulation of cellular amine metabolic process	GO:0033238	8	0.014
nucleoside monophosphate metabolic process	GO:0009123	93	0.014
response to cytokine	GO:0034097	215	0.014
microtubule organizing center organization	GO:0031023	1	0.014
positive regulation of cell death	GO:0010942	184	0.014
synaptic transmission	GO:0007268	235	0.014	Fly
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
macromolecular complex assembly	GO:0065003	273	0.014
negative regulation of multicellular organismal process	GO:0051241	203	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014	Fly
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
ribonucleotide metabolic process	GO:0009259	231	0.013
regulation of protein modification process	GO:0031399	194	0.013
regulation of transcription dna templated	GO:0006355	374	0.013	Fly
positive regulation of apoptotic process	GO:0043065	154	0.013
neuron projection morphogenesis	GO:0048812	122	0.013
central nervous system development	GO:0007417	311	0.013
response to glucocorticoid	GO:0051384	223	0.013
regulation of canonical wnt signaling pathway	GO:0060828	4	0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO:0042787	3	0.013
heterocycle catabolic process	GO:0046700	167	0.013
organic acid metabolic process	GO:0006082	292	0.013
regulation of catalytic activity	GO:0050790	304	0.013
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.013
ribonucleoside metabolic process	GO:0009119	174	0.013
cellular response to nitrogen compound	GO:1901699	210	0.012
secretion	GO:0046903	307	0.012
wnt signaling pathway	GO:0016055	17	0.012	Fly
positive regulation of developmental process	GO:0051094	283	0.012	Fly
protein homooligomerization	GO:0051260	91	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
negative regulation of phosphorus metabolic process	GO:0010563	80	0.012
macromolecule catabolic process	GO:0009057	58	0.012
positive regulation of biosynthetic process	GO:0009891	319	0.012
head development	GO:0060322	247	0.012
homeostatic process	GO:0042592	331	0.012
anatomical structure morphogenesis	GO:0009653	298	0.012
brain development	GO:0007420	247	0.012
rna metabolic process	GO:0016070	406	0.012
behavior	GO:0007610	205	0.012
positive regulation of cell development	GO:0010720	176	0.012
positive regulation of programmed cell death	GO:0043068	157	0.012
positive regulation of cellular amine metabolic process	GO:0033240	3	0.012
nucleoside monophosphate catabolic process	GO:0009125	56	0.012
response to hypoxia	GO:0001666	231	0.012
regulation of system process	GO:0044057	208	0.012
purine containing compound catabolic process	GO:0072523	138	0.012
g protein coupled receptor signaling pathway	GO:0007186	242	0.012
cellular response to hormone stimulus	GO:0032870	247	0.012
regulation of protein phosphorylation	GO:0001932	183	0.011
negative regulation of phosphate metabolic process	GO:0045936	80	0.011
centrosome organization	GO:0051297	1	0.011
cellular response to organonitrogen compound	GO:0071417	197	0.011
positive regulation of transport	GO:0051050	245	0.011
negative regulation of molecular function	GO:0044092	133	0.011
response to decreased oxygen levels	GO:0036293	237	0.011
nucleoside catabolic process	GO:0009164	126	0.011
single organism catabolic process	GO:0044712	283	0.011
positive regulation of phosphorylation	GO:0042327	177	0.011
cellular ketone metabolic process	GO:0042180	51	0.011
protein catabolic process	GO:0030163	30	0.011
negative regulation of gene expression	GO:0010629	199	0.011
protein complex biogenesis	GO:0070271	263	0.011
nucleic acid templated transcription	GO:0097659	379	0.011
negative regulation of signaling	GO:0023057	157	0.011
response to corticosteroid	GO:0031960	235	0.011
regulation of cellular protein metabolic process	GO:0032268	267	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011
macromolecular complex subunit organization	GO:0043933	339	0.011
purine nucleoside catabolic process	GO:0006152	124	0.011
response to acid chemical	GO:0001101	222	0.011
protein complex subunit organization	GO:0071822	302	0.011
glycosyl compound catabolic process	GO:1901658	126	0.011
nucleotide biosynthetic process	GO:0009165	98	0.011
neuron death	GO:0070997	127	0.011
regulation of multicellular organismal development	GO:2000026	376	0.011	Fly
rho protein signal transduction	GO:0007266	11	0.011
regulation of nervous system development	GO:0051960	264	0.011	Fly
nucleobase containing compound catabolic process	GO:0034655	152	0.010
cellular response to peptide	GO:1901653	133	0.010
mitotic spindle organization	GO:0007052	2	0.010
cation transport	GO:0006812	382	0.010
ribonucleotide catabolic process	GO:0009261	136	0.010
transmission of nerve impulse	GO:0019226	42	0.010
positive regulation of cell differentiation	GO:0045597	217	0.010
positive regulation of cellular component organization	GO:0051130	200	0.010	Fly
lipid biosynthetic process	GO:0008610	128	0.010
cell projection organization	GO:0030030	302	0.010
negative regulation of catalytic activity	GO:0043086	103	0.010

Snx16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.033
disease of anatomical entity	DOID:7	0.033
central nervous system disease	DOID:331	0.018
sensory system disease	DOID:0050155	0.012

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