Rattus norvegicus

24 known processes

Pon1

paraoxonase 1

Pon1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inflammatory responseGO:00069541500.355
organic acid metabolic processGO:00060822920.333
Human Rat
alkaloid metabolic processGO:000982030.331
cellular response to oxygen containing compoundGO:19017013860.321
response to extracellular stimulusGO:00099913800.290
organic hydroxy compound metabolic processGO:19016151150.263
Human
positive regulation of multicellular organismal processGO:00512403870.245
negative regulation of gene expressionGO:00106291990.244
response to metal ionGO:00100382530.236
positive regulation of cell proliferationGO:00082842490.228
cellular response to lipidGO:00713962010.212
programmed cell deathGO:00125013920.209
response to peptide hormoneGO:00434342780.208
response to peptideGO:19016522920.208
homeostatic processGO:00425923310.199
carboxylic acid metabolic processGO:00197522890.196
Human Rat
regulation of programmed cell deathGO:00430673410.193
regulation of cell proliferationGO:00421273590.189
response to estradiolGO:00323551640.181
agingGO:00075682410.179
positive regulation of transportGO:00510502450.177
Human
multi multicellular organism processGO:00447061380.173
response to biotic stimulusGO:00096072260.172
response to acid chemicalGO:00011012220.171
oxoacid metabolic processGO:00434362900.168
Human Rat
regulation of system processGO:00440572080.155
response to nutrientGO:00075842480.143
response to woundingGO:00096112540.142
blood circulationGO:00080151830.139
response to nutrient levelsGO:00316673700.136
reproductive processGO:00224143720.134
regulation of apoptotic processGO:00429813350.134
cellular homeostasisGO:00197252520.129
response to insulinGO:00328681330.123
chemical homeostasisGO:00488782920.115
response to purine containing compoundGO:00140741260.114
positive regulation of secretion by cellGO:19035321280.112
response to lipopolysaccharideGO:00324961910.109
vesicle mediated transportGO:00161921810.105
response to calcium ionGO:0051592590.103
negative regulation of metabolic processGO:00098923310.099
cellular response to endogenous stimulusGO:00714953770.099
macromolecule localizationGO:00330362520.098
Human
gland developmentGO:00487321550.097
immune responseGO:00069551040.095
response to estrogenGO:00436272320.094
response to cytokineGO:00340972150.093
apoptotic processGO:00069153810.089
liver developmentGO:0001889900.088
response to corticosteroidGO:00319602350.088
fatty acid metabolic processGO:0006631990.085
lipid localizationGO:0010876620.085
Human
response to glucoseGO:00097491360.084
pyridine containing compound metabolic processGO:0072524320.082
regulation of protein metabolic processGO:00512462890.080
immune system processGO:00023762040.079
small molecule biosynthetic processGO:00442831240.079
negative regulation of cellular biosynthetic processGO:00313271610.079
response to monosaccharideGO:00342841590.078
positive regulation of secretionGO:00510471400.078
behaviorGO:00076102050.077
developmental process involved in reproductionGO:00030061590.077
cellular lipid metabolic processGO:00442552080.077
Human
regulation of secretionGO:00510462240.077
locomotionGO:00400112370.076
cell motilityGO:00488702020.075
regulation of secretion by cellGO:19035302080.073
regulation of locomotionGO:00400121480.071
response to radiationGO:00093141370.071
negative regulation of rna metabolic processGO:00512531230.070
long chain fatty acid metabolic processGO:0001676320.070
reproductive system developmentGO:00614581280.070
positive regulation of programmed cell deathGO:00430681570.069
negative regulation of nucleobase containing compound metabolic processGO:00459341530.069
response to carbohydrateGO:00097431830.068
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.067
cellular ketone metabolic processGO:0042180510.067
hepaticobiliary system developmentGO:0061008900.067
regulation of immune system processGO:00026821230.066
negative regulation of macromolecule metabolic processGO:00106052600.066
negative regulation of nitrogen compound metabolic processGO:00511721610.065
cellular response to nitrogen compoundGO:19016992100.065
regulation of molecular functionGO:00650093980.065
Human
response to inorganic substanceGO:00100353770.064
neuron deathGO:00709971270.063
cellular amino acid metabolic processGO:00065201070.063
response to ionizing radiationGO:0010212590.063
hormone metabolic processGO:0042445690.063
response to bacteriumGO:00096172000.063
regenerationGO:00310991630.062
positive regulation of cell differentiationGO:00455972170.061
negative regulation of cellular metabolic processGO:00313242810.060
secretionGO:00469033070.059
cellular response to hormone stimulusGO:00328702470.059
cellular chemical homeostasisGO:00550822470.058
regulation of rna metabolic processGO:00512523910.057
localization of cellGO:00516742020.057
positive regulation of gene expressionGO:00106282440.057
oligopeptide transportGO:000685740.057
tissue developmentGO:00098882520.055
female pregnancyGO:00075651220.054
leukocyte mediated immunityGO:0002443280.053
negative regulation of cell proliferationGO:00082851190.053
regulation of serine type peptidase activityGO:190257110.053
halogenated hydrocarbon metabolic processGO:004219740.053
response to cesium ionGO:001016420.052
multi organism reproductive processGO:00447032620.052
defecationGO:003042110.050
macromolecular complex assemblyGO:00650032730.050
transmembrane transportGO:00550854120.050
naphthalene containing compound metabolic processGO:009042020.050
protein transportGO:00150311320.049
reproductionGO:00000032450.049
cellular amine metabolic processGO:0044106380.048
Human
regulation of cellular component organizationGO:00511283680.047
lipid metabolic processGO:00066292830.047
macromolecular complex subunit organizationGO:00439333390.047
reproductive structure developmentGO:00486081280.046
second messenger mediated signalingGO:0019932510.046
regulation of hydrolase activityGO:00513361430.046
organic hydroxy compound biosynthetic processGO:1901617510.045
regulation of cell differentiationGO:00455953200.045
ion homeostasisGO:00508012120.045
regulation of catalytic activityGO:00507903040.045
divalent metal ion transportGO:00708381320.045
response to growth factorGO:00708481890.045
negative regulation of cell differentiationGO:0045596990.043
cellular ion homeostasisGO:00068731840.042
oxidation reduction processGO:00551143040.042
protein complex assemblyGO:00064612630.041
cellular response to organic cyclic compoundGO:00714072020.041
response to external biotic stimulusGO:00432072210.041
isoprenoid metabolic processGO:0006720450.041
regulation of multicellular organismal developmentGO:20000263760.041
development of primary sexual characteristicsGO:00451371070.040
regulation of rna biosynthetic processGO:20011413810.040
hormone transportGO:00099141210.040
positive regulation of molecular functionGO:00440932300.040
Human
cell migrationGO:00164771970.039
negative regulation of programmed cell deathGO:00430691830.039
cellular component movementGO:00069282480.039
multicellular organism reproductionGO:00325042330.039
response to vitaminGO:00332731310.039
positive regulation of cellular biosynthetic processGO:00313282950.039
response to hexoseGO:00097461440.039
norepinephrine secretionGO:0048243160.039
feeding behaviorGO:0007631530.039
protein complex subunit organizationGO:00718223020.038
response to organophosphorusGO:00466831020.038
positive regulation of response to stimulusGO:00485842850.037
steroid metabolic processGO:0008202730.037
negative regulation of serine type endopeptidase activityGO:190000410.037
cellular component assemblyGO:00226073600.037
lipid biosynthetic processGO:00086101280.037
multicellular organismal reproductive processGO:00486092330.037
positive regulation of protein metabolic processGO:00512471780.037
secretion by cellGO:00329402480.037
monocarboxylic acid biosynthetic processGO:0072330480.037
rna biosynthetic processGO:00327743800.037
trichloroethylene metabolic processGO:001897910.035
response to decreased oxygen levelsGO:00362932370.035
phenol containing compound metabolic processGO:0018958300.035
insecticide metabolic processGO:001714340.035
sex differentiationGO:00075481130.035
regulation of serine type endopeptidase activityGO:190000310.035
negative regulation of phosphorus metabolic processGO:0010563800.034
single organism biosynthetic processGO:00447113420.034
alcohol metabolic processGO:0006066770.034
Human
nitrogen compound transportGO:00717052290.034
cellular response to growth factor stimulusGO:00713631620.034
response to molecule of bacterial originGO:00022371940.034
negative regulation of biosynthetic processGO:00098901680.034
exogenous drug catabolic processGO:004273810.033
negative regulation of nucleic acid templated transcriptionGO:19035071170.033
response to ketoneGO:19016541820.033
detection of stimulusGO:0051606240.033
cellular response to stressGO:00335542690.032
central nervous system developmentGO:00074173110.032
sexual reproductionGO:00199531480.032
cation homeostasisGO:00550801950.032
cellular response to cytokine stimulusGO:00713451270.032
reactive nitrogen species metabolic processGO:200105710.032
regulation of response to stressGO:00801341260.031
positive regulation of cellular component organizationGO:00511302000.031
peptide transportGO:0015833970.031
positive regulation of cell deathGO:00109421840.031
regulation of transcription dna templatedGO:00063553740.031
regulation of defecationGO:200029210.031
single organism reproductive processGO:00447022970.030
peptide secretionGO:0002790860.030
negative regulation of cell deathGO:00605482290.030
neuron developmentGO:00486662860.029
single organism intracellular transportGO:19025821660.029
response to sulfur dioxideGO:001047730.029
positive regulation of locomotionGO:00400171020.029
regulation of cellular amino acid metabolic processGO:000652120.029
negative regulation of developmental processGO:00510931250.028
detection of visible lightGO:000958430.028
negative regulation of apoptotic processGO:00430661810.028
negative regulation of calcium ion importGO:009028120.028
response to glucocorticoidGO:00513842230.028
sensory perceptionGO:00076001010.028
regulation of cellular amine metabolic processGO:003323880.028
response to ethanolGO:00454711620.028
cell projection organizationGO:00300303020.028
cellular cation homeostasisGO:00300031800.028
cellular response to organonitrogen compoundGO:00714171970.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
positive regulation of developmental processGO:00510942830.027
negative regulation of molecular functionGO:00440921330.027
positive regulation of rna biosynthetic processGO:19026801970.027
response to oxidative stressGO:00069791860.027
Rat
cell type specific apoptotic processGO:00972851340.027
negative regulation of response to stimulusGO:00485851550.027
steroid biosynthetic processGO:0006694480.027
regulation of calcium ion transportGO:0051924770.027
positive regulation of cellular amino acid metabolic processGO:004576410.027
response to mechanical stimulusGO:00096121340.027
transmission of nerve impulseGO:0019226420.026
cellular response to external stimulusGO:00714961180.026
cell cell signalingGO:00072673350.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
positive regulation of serotonin secretionGO:001406410.026
organ morphogenesisGO:0009887750.026
regulation of inflammatory responseGO:0050727480.026
organic hydroxy compound transportGO:0015850770.026
Human
heart morphogenesisGO:000300730.026
circulatory system processGO:00030131830.026
nicotine metabolic processGO:001893310.025
calcium ion importGO:0070509220.025
response to other organismGO:00517072200.025
amine metabolic processGO:0009308380.025
Human
female sex differentiationGO:0046660590.025
neuron apoptotic processGO:0051402880.025
regulation of phosphorus metabolic processGO:00511743490.025
regulation of cellular localizationGO:00603412630.025
growthGO:00400071650.024
cellular component biogenesisGO:00440853680.024
positive regulation of apoptotic processGO:00430651540.024
synaptic transmissionGO:00072682350.024
monocarboxylic acid metabolic processGO:00327871520.024
Rat
positive regulation of peptide hormone secretionGO:0090277500.023
negative regulation of signalingGO:00230571570.023
rna metabolic processGO:00160704060.023
regulation of response to external stimulusGO:00321011060.023
regulation of signal transductionGO:00099663180.023
positive regulation of reactive oxygen species metabolic processGO:2000379160.023
transcription from rna polymerase ii promoterGO:00063662520.023
regulation of norepinephrine secretionGO:0014061150.023
negative regulation of cell developmentGO:0010721820.023
eye morphogenesisGO:004859240.023
negative regulation of multicellular organismal processGO:00512412030.023
cellular response to steroid hormone stimulusGO:0071383930.023
neuron projection developmentGO:00311752730.023
regulation of catecholamine secretionGO:0050433320.023
regulation of cellular ketone metabolic processGO:0010565270.022
protein localizationGO:00081041910.022
negative regulation of transcription dna templatedGO:00458921160.022
cation transportGO:00068123820.022
regulation of cell projection organizationGO:00313441750.022
negative regulation of cellular protein metabolic processGO:00322691060.022
signal releaseGO:00230611450.022
organ regenerationGO:00311001010.022
positive regulation of cell projection organizationGO:00313461110.022
negative regulation of protein metabolic processGO:00512481140.021
hormone secretionGO:00468791150.021
positive regulation of exocytosisGO:0045921190.021
cellular response to lipopolysaccharideGO:0071222550.021
calcium ion homeostasisGO:00550741620.021
dicarboxylic acid transportGO:0006835340.021
glycerolipid metabolic processGO:0046486670.021
Human
regulation of vesicle mediated transportGO:0060627810.021
positive regulation of blood circulationGO:1903524650.021
regulation of glucose transportGO:0010827180.021
regulation of peptide hormone secretionGO:0090276800.021
regulation of hormone levelsGO:00108171870.021
negative regulation of cell communicationGO:00106481580.021
cellular metal ion homeostasisGO:00068751720.021
brain developmentGO:00074202470.021
cellular response to alcoholGO:0097306870.020
calcitriol biosynthetic process from calciolGO:003637820.020
anatomical structure morphogenesisGO:00096532980.020
positive regulation of transcription dna templatedGO:00458931970.020
cellular calcium ion homeostasisGO:00068741600.020
glucose homeostasisGO:0042593750.020
regulation of reactive oxygen species metabolic processGO:2000377260.020
nucleic acid templated transcriptionGO:00976593790.020
gamete generationGO:00072761240.020
drug metabolic processGO:0017144110.019
positive regulation of signalingGO:00230562700.019
regulation of reactive oxygen species biosynthetic processGO:190342650.019
regulation of anatomical structure sizeGO:00900661350.019
response to alkaloidGO:00432791320.019
regulation of nucleic acid templated transcriptionGO:19035063800.019
locomotory exploration behaviorGO:003564110.019
calcium ion transportGO:00068161310.019
regulation of carbohydrate metabolic processGO:0006109410.019
regulation of excretionGO:0044062210.019
renin angiotensin regulation of aldosterone productionGO:000201830.019
circadian rhythmGO:0007623880.019
regulation of cell migrationGO:00303341280.019
regulation of neuron deathGO:19012141150.018
regulation of cellular protein metabolic processGO:00322682670.018
regulation of blood pressureGO:0008217830.018
positive regulation of peptide secretionGO:0002793520.018
defense responseGO:00069521940.018
positive regulation of cellular component movementGO:00512721020.018
anatomical structure formation involved in morphogenesisGO:0048646830.018
protein complex biogenesisGO:00702712630.018
protein phosphorylationGO:00064683450.018
mapk cascadeGO:00001651400.018
negative regulation of catalytic activityGO:00430861030.018
development of primary male sexual characteristicsGO:0046546590.018
lipid transportGO:0006869610.018
Human
negative regulation of innate immune responseGO:004582440.018
response to transition metal nanoparticleGO:19902671220.018
establishment of protein localizationGO:00451841410.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
positive regulation of cellular amine metabolic processGO:003324030.018
epithelium developmentGO:0060429960.017
positive regulation of cell communicationGO:00106472710.017
neurological system processGO:00508772190.017
negative regulation of growthGO:0045926370.017
transcription dna templatedGO:00063513770.017
protein targetingGO:0006605610.017
cellular response to abiotic stimulusGO:0071214850.017
metal ion transportGO:00300012890.017
coenzyme metabolic processGO:0006732860.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
negative regulation of neurogenesisGO:0050768780.017
catecholamine secretionGO:0050432330.017
regulation of peptide transportGO:0090087870.017
regulation of cellular component movementGO:00512701500.017
response to vitamin aGO:0033189360.017
response to activityGO:0014823730.017
regulation of peptide secretionGO:0002791820.017
response to toxic substanceGO:00096361330.016
epoxygenase p450 pathwayGO:001937310.016
spermatogenesisGO:0007283990.016
triglyceride metabolic processGO:0006641210.016
positive regulation of catalytic activityGO:00430851840.016
positive regulation of cellular protein metabolic processGO:00322701670.016
protein oligomerizationGO:00512591910.016
regulation of phosphorylationGO:00423252480.016
axis specificationGO:000979840.016
immune system developmentGO:0002520410.016
anterior posterior pattern specificationGO:000995210.016
hexose transportGO:0008645290.016
positive regulation of biosynthetic processGO:00098913190.016
norepinephrine transportGO:0015874180.016
divalent inorganic cation transportGO:00725111340.015
protein tetramerizationGO:0051262380.015
intracellular signal transductionGO:00355563140.015
regulation of metal ion transportGO:00109591180.015
regulation of cell motilityGO:20001451310.015
negative regulation of neuron deathGO:1901215690.015
positive regulation of hydrolase activityGO:0051345860.015
catechol containing compound metabolic processGO:0009712190.015
angiotensin mediated drinking behaviorGO:000305120.015
regulation of growthGO:00400081050.015
positive regulation of signal transductionGO:00099671750.015
male gonad developmentGO:0008584590.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
metal ion homeostasisGO:00550651860.015
protein secretionGO:0009306340.015
terpenoid metabolic processGO:0006721370.015
response to potassium ionGO:003586490.015
regulation of phosphate metabolic processGO:00192203490.015
single organism organelle organizationGO:19025891800.015
regulation of neuron apoptotic processGO:0043523830.015
proteolysisGO:00065081750.014
response to methanolGO:003398610.014
embryonic pattern specificationGO:000988010.014
response to ddtGO:004668010.014
amide transportGO:00428861050.014
sulfur compound metabolic processGO:0006790700.014
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.014
negative regulation of serine type peptidase activityGO:190257210.014
regulation of proteolysisGO:0030162660.014
cellular response to hexose stimulusGO:0071331650.014
gonad developmentGO:00084061040.014
immunoglobulin mediated immune responseGO:001606440.014
positive regulation of homeostatic processGO:0032846490.014
single organism carbohydrate metabolic processGO:00447231180.014
positive regulation of phosphate metabolic processGO:00459372620.014
response to vitamin dGO:0033280340.014
digestive system processGO:0022600240.014
negative regulation of phosphate metabolic processGO:0045936800.014
cellular response to biotic stimulusGO:0071216590.014
carbohydrate homeostasisGO:0033500750.014
regulation of neurotransmitter transportGO:0051588210.014
developmental growthGO:00485891000.014
mammary gland developmentGO:0030879380.013
development of primary female sexual characteristicsGO:0046545560.013
epinephrine secretionGO:004824260.013
nuclear importGO:0051170350.013
cellular response to extracellular stimulusGO:0031668730.013
tolerance induction dependent upon immune responseGO:000246120.013
carbohydrate metabolic processGO:00059751300.013
neuron differentiationGO:00301823680.013
lipid storageGO:001991510.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
regulation of response to woundingGO:1903034690.013
carbohydrate derivative metabolic processGO:19011353460.013
cytoplasmic transportGO:00164821150.013
positive regulation of immune system processGO:0002684900.013
naphthalene metabolic processGO:001893120.013
cardiovascular system developmentGO:00723581340.013
male sex differentiationGO:0046661640.013
regulation of ion transportGO:00432692450.013
negative regulation of protein maturationGO:1903318470.013
single organism cellular localizationGO:19025801020.013
protein maturationGO:0051604680.013
negative regulation of rna biosynthetic processGO:19026791180.013
cellular catabolic processGO:00442482950.013
Human Rat
response to chromateGO:004668730.013
response to hydrogen peroxideGO:0042542890.013
positive regulation of rna metabolic processGO:00512542030.013
catecholamine biosynthetic processGO:004242390.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of cell growthGO:0001558850.013
regulation of transferase activityGO:00513381230.013
b cell mediated immunityGO:001972440.013
positive regulation of kinase activityGO:0033674770.013
positive regulation of blood coagulationGO:003019440.013
cellular response to peptide hormone stimulusGO:00713751200.013
cofactor metabolic processGO:0051186950.013
response to corticosteroneGO:0051412400.013
cell activationGO:0001775970.013
drug catabolic processGO:004273710.013
response to hypoxiaGO:00016662310.013
regulation of defense responseGO:0031347680.013
digestionGO:0007586260.012
organic acid transportGO:00158491160.012
cellular response to glucose stimulusGO:0071333650.012
lymphocyte activation involved in immune responseGO:000228530.012
response to insecticideGO:0017085210.012
response to osmotic stressGO:0006970420.012
head developmentGO:00603222470.012
catenin import into nucleusGO:003541110.012
negative regulation of signal transductionGO:0009968830.012
unsaturated fatty acid metabolic processGO:0033559390.012
activation of protein kinase activityGO:0032147470.012
regulation of exocytosisGO:0017157370.012
cellular response to acid chemicalGO:0071229750.012
single organism cell adhesionGO:0098602460.012
positive regulation of tolerance induction dependent upon immune responseGO:000265410.012
hexose metabolic processGO:0019318580.012
alcohol biosynthetic processGO:0046165380.012
erythrocyte differentiationGO:003021810.012
cellular carbohydrate metabolic processGO:0044262720.012
regulation of synaptic transmissionGO:00508041410.012
regulation of peptidase activityGO:0052547550.012
negative regulation of camp biosynthetic processGO:0030818120.012
organelle organizationGO:00069962660.012
retina morphogenesis in camera type eyeGO:006004210.012
polyol biosynthetic processGO:0046173130.012
cytokine productionGO:0001816610.012
embryonic skeletal system developmentGO:004870630.012
ion transmembrane transportGO:00342203650.011
regulation of synaptic plasticityGO:0048167700.011
icosanoid metabolic processGO:0006690380.011
vitamin transportGO:0051180140.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
regulation of immune response to tumor cellGO:000283730.011
regulation of smooth muscle cell proliferationGO:0048660750.011
nucleobase containing small molecule metabolic processGO:00550863160.011
secondary alcohol metabolic processGO:190265220.011
organic anion transportGO:00157111320.011
defense response to gram negative bacteriumGO:005082930.011
hemopoiesisGO:0030097340.011
response to axon injuryGO:0048678590.011
polyol metabolic processGO:0019751200.011
intracellular protein transportGO:0006886790.011
cellular response to xenobiotic stimulusGO:0071466190.011
Rat
arachidonic acid metabolic processGO:0019369200.011
response to oxygen levelsGO:00704822650.011
xenobiotic metabolic processGO:0006805190.011
Rat
negative regulation of nervous system developmentGO:0051961790.011
ossificationGO:0001503700.011
cellular glucose homeostasisGO:0001678660.011
gastric motilityGO:003548230.011
negative regulation of cell growthGO:0030308330.011
regulation of cellular carbohydrate metabolic processGO:0010675390.011

Pon1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
retinal diseaseDOID:567900.028
sensory system diseaseDOID:005015500.028
eye and adnexa diseaseDOID:149200.028
night blindnessDOID:849900.028
eye diseaseDOID:561400.028
nervous system diseaseDOID:86300.028
retinal degenerationDOID:846600.013
retinitis pigmentosaDOID:1058400.013
endocrine system diseaseDOID:2800.013
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011