Rattus norvegicus

97 known processes

Grik2

glutamate receptor, ionotropic, kainate 2

(Aliases: GluR6)

Grik2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cell communicationGO:00106472710.250
Human Rat
positive regulation of signalingGO:00230562700.158
Human Rat
positive regulation of multicellular organismal processGO:00512403870.122
signal transduction by phosphorylationGO:00230141440.113
macromolecule localizationGO:00330362520.111
regulation of molecular functionGO:00650093980.097
intracellular signal transductionGO:00355563140.095
regulation of cellular component organizationGO:00511283680.093
positive regulation of catalytic activityGO:00430851840.090
central nervous system developmentGO:00074173110.086
neuron developmentGO:00486662860.086
positive regulation of developmental processGO:00510942830.084
carboxylic acid metabolic processGO:00197522890.083
oxoacid metabolic processGO:00434362900.081
organic acid metabolic processGO:00060822920.077
cell projection organizationGO:00300303020.077
single organism biosynthetic processGO:00447113420.075
positive regulation of phosphate metabolic processGO:00459372620.075
regulation of nervous system developmentGO:00519602640.074
regulation of mapk cascadeGO:00434081160.073
regulation of neuron deathGO:19012141150.072
positive regulation of response to stimulusGO:00485842850.070
regulation of catalytic activityGO:00507903040.069
positive regulation of phosphorus metabolic processGO:00105622620.067
positive regulation of intracellular signal transductionGO:19025331380.066
reproductive processGO:00224143720.066
positive regulation of signal transductionGO:00099671750.064
brain developmentGO:00074202470.062
apoptotic processGO:00069153810.059
positive regulation of cellular component organizationGO:00511302000.059
response to extracellular stimulusGO:00099913800.058
regulation of phosphorus metabolic processGO:00511743490.058
lipid metabolic processGO:00066292830.057
head developmentGO:00603222470.056
positive regulation of kinase activityGO:0033674770.053
protein localizationGO:00081041910.052
positive regulation of cellular protein metabolic processGO:00322701670.051
positive regulation of molecular functionGO:00440932300.051
regulation of cell differentiationGO:00455953200.051
cellular amino acid metabolic processGO:00065201070.051
cell cell signalingGO:00072673350.051
regulation of transcription dna templatedGO:00063553740.050
regulation of programmed cell deathGO:00430673410.050
regulation of rna biosynthetic processGO:20011413810.049
transcription dna templatedGO:00063513770.049
positive regulation of protein phosphorylationGO:00019341350.049
regulation of phosphate metabolic processGO:00192203490.049
regulation of phosphorylationGO:00423252480.047
positive regulation of apoptotic processGO:00430651540.047
protein complex subunit organizationGO:00718223020.047
Rat
neuron deathGO:00709971270.046
single organism reproductive processGO:00447022970.046
regulation of cellular localizationGO:00603412630.046
nucleic acid templated transcriptionGO:00976593790.046
regulation of signal transductionGO:00099663180.046
sulfur compound metabolic processGO:0006790700.046
neuron projection developmentGO:00311752730.046
positive regulation of nitrogen compound metabolic processGO:00511733340.046
positive regulation of biosynthetic processGO:00098913190.045
small molecule biosynthetic processGO:00442831240.045
metal ion transportGO:00300012890.044
regulation of neuron differentiationGO:00456642080.044
regulation of multicellular organismal developmentGO:20000263760.043
single organism cellular localizationGO:19025801020.043
rna biosynthetic processGO:00327743800.043
multi organism reproductive processGO:00447032620.042
regulation of intracellular signal transductionGO:19025312180.042
positive regulation of transferase activityGO:0051347810.042
blood circulationGO:00080151830.042
anatomical structure morphogenesisGO:00096532980.041
regulation of rna metabolic processGO:00512523910.041
positive regulation of cell differentiationGO:00455972170.041
positive regulation of cellular biosynthetic processGO:00313282950.041
response to nutrient levelsGO:00316673700.041
regulation of cellular protein metabolic processGO:00322682670.040
positive regulation of phosphorylationGO:00423271770.040
cellular component assemblyGO:00226073600.039
Rat
protein transportGO:00150311320.039
protein phosphorylationGO:00064683450.039
homeostatic processGO:00425923310.039
multicellular organismal reproductive processGO:00486092330.039
reproductionGO:00000032450.038
positive regulation of protein modification processGO:00314011420.038
response to nutrientGO:00075842480.038
regulation of locomotionGO:00400121480.038
regulation of neuron apoptotic processGO:0043523830.038
regulation of protein phosphorylationGO:00019321830.038
inorganic ion transmembrane transportGO:00986602290.038
maintenance of locationGO:0051235170.038
regulation of protein kinase activityGO:00458591050.037
organophosphate metabolic processGO:00196373700.037
regulation of transferase activityGO:00513381230.037
regulation of cell projection organizationGO:00313441750.036
response to oxygen levelsGO:00704822650.036
response to peptideGO:19016522920.036
synaptic growth at neuromuscular junctionGO:005112410.036
ion transmembrane transportGO:00342203650.036
positive regulation of neurogenesisGO:00507691650.035
locomotionGO:00400112370.034
response to inorganic substanceGO:00100353770.034
Rat
transcription from rna polymerase ii promoterGO:00063662520.034
response to hypoxiaGO:00016662310.034
cellular ketone metabolic processGO:0042180510.034
positive regulation of protein metabolic processGO:00512471780.034
response to metal ionGO:00100382530.034
Rat
neuron apoptotic processGO:0051402880.033
positive regulation of nervous system developmentGO:00519621780.033
positive regulation of nucleobase containing compound metabolic processGO:00459353190.033
positive regulation of cell developmentGO:00107201760.033
cellular response to stressGO:00335542690.033
regulation of protein localizationGO:0032880810.033
macromolecular complex assemblyGO:00650032730.033
Rat
cellular amine metabolic processGO:0044106380.033
response to other organismGO:00517072200.033
lipid biosynthetic processGO:00086101280.033
positive regulation of mapk cascadeGO:0043410920.032
response to corticosteroidGO:00319602350.032
regulation of kinase activityGO:00435491170.032
regulation of vesicle mediated transportGO:0060627810.032
cation transportGO:00068123820.032
regulation of neurogenesisGO:00507672470.032
purine containing compound metabolic processGO:00725212530.032
multicellular organism reproductionGO:00325042330.032
neuron differentiationGO:00301823680.032
secretionGO:00469033070.031
protein complex assemblyGO:00064612630.031
Rat
regulation of synaptic transmissionGO:00508041410.031
positive regulation of neuron projection developmentGO:0010976990.031
ion homeostasisGO:00508012120.031
cellular response to oxygen containing compoundGO:19017013860.031
cellular homeostasisGO:00197252520.031
cell migrationGO:00164771970.030
regulation of protein metabolic processGO:00512462890.030
cation transmembrane transportGO:00986552630.029
nucleobase containing small molecule metabolic processGO:00550863160.029
response to decreased oxygen levelsGO:00362932370.029
organelle organizationGO:00069962660.029
growthGO:00400071650.028
regulation of nucleic acid templated transcriptionGO:19035063800.028
response to glucocorticoidGO:00513842230.028
cellular cation homeostasisGO:00300031800.028
negative regulation of metabolic processGO:00098923310.028
single organism intracellular transportGO:19025821660.027
regulation of cell developmentGO:00602842630.027
negative regulation of cellular metabolic processGO:00313242810.027
regulation of membrane potentialGO:00423911100.027
Rat
positive regulation of protein kinase activityGO:0045860730.027
positive regulation of transportGO:00510502450.027
nucleoside phosphate metabolic processGO:00067532830.026
regulation of protein transportGO:0051223680.026
regulation of apoptotic processGO:00429813350.026
regulation of establishment of protein localizationGO:0070201690.026
cellular calcium ion homeostasisGO:00068741600.026
nucleoside metabolic processGO:00091161790.026
regulation of cell proliferationGO:00421273590.026
cellular metal ion homeostasisGO:00068751720.025
cellular component movementGO:00069282480.025
cellular lipid metabolic processGO:00442552080.025
synaptic transmissionGO:00072682350.025
rna metabolic processGO:00160704060.025
muscle system processGO:00030121150.025
agingGO:00075682410.025
protein targetingGO:0006605610.025
regulation of proteasomal protein catabolic processGO:006113640.025
cellular response to endogenous stimulusGO:00714953770.025
amine metabolic processGO:0009308380.025
sensory perceptionGO:00076001010.024
regulation of secretion by cellGO:19035302080.024
regulation of response to stressGO:00801341260.024
carbohydrate derivative metabolic processGO:19011353460.024
cellular response to hormone stimulusGO:00328702470.024
positive regulation of cell projection organizationGO:00313461110.024
regulation of cellular amine metabolic processGO:003323880.023
response to purine containing compoundGO:00140741260.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
activation of protein kinase activityGO:0032147470.023
negative regulation of gene expressionGO:00106291990.023
regulation of hormone levelsGO:00108171870.023
carbohydrate metabolic processGO:00059751300.023
regulation of cellular ketone metabolic processGO:0010565270.023
peptidyl tyrosine phosphorylationGO:0018108720.023
response to estrogenGO:00436272320.023
regulation of cellular amino acid metabolic processGO:000652120.023
response to woundingGO:00096112540.023
small gtpase mediated signal transductionGO:0007264360.023
secretion by cellGO:00329402480.023
establishment of protein localizationGO:00451841410.022
Rat
regulation of protein modification processGO:00313991940.022
programmed cell deathGO:00125013920.022
single organism catabolic processGO:00447122830.022
negative regulation of transcription dna templatedGO:00458921160.022
ribose phosphate metabolic processGO:00196932350.022
macromolecular complex subunit organizationGO:00439333390.022
Rat
transmembrane transportGO:00550854120.021
cellular modified amino acid metabolic processGO:0006575610.021
glycosyl compound catabolic processGO:19016581260.021
divalent inorganic cation homeostasisGO:00725071650.021
positive regulation of neuron differentiationGO:00456661260.021
cytosolic calcium ion homeostasisGO:00514801400.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
cellular response to peptide hormone stimulusGO:00713751200.021
adult locomotory behaviorGO:000834440.021
ras protein signal transductionGO:0007265290.021
nucleotide metabolic processGO:00091172790.021
response to carbohydrateGO:00097431830.020
cellular chemical homeostasisGO:00550822470.020
circulatory system processGO:00030131830.020
organic hydroxy compound transportGO:0015850770.020
neurological system processGO:00508772190.020
response to bacteriumGO:00096172000.020
signal releaseGO:00230611450.020
positive regulation of gene expressionGO:00106282440.020
response to glucoseGO:00097491360.020
response to peptide hormoneGO:00434342780.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
positive regulation of neuron deathGO:1901216430.020
negative regulation of multicellular organismal processGO:00512412030.020
response to ethanolGO:00454711620.019
cellular protein localizationGO:00346131220.019
actin filament based processGO:0030029860.019
single organism behaviorGO:00447081300.019
localization of cellGO:00516742020.019
regulation of secretionGO:00510462240.019
negative regulation of signalingGO:00230571570.019
positive regulation of transcription dna templatedGO:00458931970.019
multi multicellular organism processGO:00447061380.019
cell morphogenesisGO:00009021420.019
anion transportGO:00068201780.019
positive regulation of cell deathGO:00109421840.019
neuronal action potentialGO:0019228350.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
positive regulation of cellular amine metabolic processGO:003324030.018
protein complex biogenesisGO:00702712630.018
Rat
regulation of homeostatic processGO:00328441010.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
calcium ion homeostasisGO:00550741620.018
intracellular transportGO:00469071850.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
regulation of protein serine threonine kinase activityGO:0071900640.018
vesicle mediated transportGO:00161921810.018
Rat
negative regulation of rna biosynthetic processGO:19026791180.018
response to cytokineGO:00340972150.018
synapse organizationGO:0050808460.018
cellular ion homeostasisGO:00068731840.018
rhythmic processGO:00485111560.018
negative regulation of cell deathGO:00605482290.018
protein localization to organelleGO:0033365570.018
catabolic processGO:00090563510.018
defense responseGO:00069521940.018
regulation of ion transportGO:00432692450.018
cell type specific apoptotic processGO:00972851340.017
response to biotic stimulusGO:00096072260.017
cytoskeleton organizationGO:00070101110.017
regulation of dendrite developmentGO:0050773590.017
multicellular organism growthGO:003526410.017
intracellular protein transportGO:0006886790.017
negative regulation of cellular biosynthetic processGO:00313271610.017
positive regulation of synaptic vesicle transportGO:190280530.017
chemical homeostasisGO:00488782920.017
mapk cascadeGO:00001651400.017
steroid metabolic processGO:0008202730.017
regulation of hydrolase activityGO:00513361430.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
organophosphate biosynthetic processGO:00904071430.017
negative regulation of response to stimulusGO:00485851550.017
purine nucleotide metabolic processGO:00061632290.017
potassium ion transportGO:0006813970.017
negative regulation of transportGO:00510511360.017
nitrogen compound transportGO:00717052290.017
negative regulation of programmed cell deathGO:00430691830.017
developmental growthGO:00485891000.016
action potentialGO:0001508540.016
protein oligomerizationGO:00512591910.016
Rat
regulation of system processGO:00440572080.016
cellular response to external stimulusGO:00714961180.016
reproductive structure developmentGO:00486081280.016
response to alkaloidGO:00432791320.016
sequestering of calcium ionGO:005120880.016
regulation of cellular component biogenesisGO:0044087860.016
gland developmentGO:00487321550.016
transmission of nerve impulseGO:0019226420.016
oxidation reduction processGO:00551143040.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
fatty acid metabolic processGO:0006631990.016
calcium ion transport into cytosolGO:0060402380.016
divalent metal ion transportGO:00708381320.016
multicellular organismal signalingGO:0035637440.016
cytoplasmic transportGO:00164821150.015
regulation of metal ion transportGO:00109591180.015
positive regulation of secretionGO:00510471400.015
eye morphogenesisGO:004859240.015
protein import into nucleusGO:0006606350.015
negative regulation of rna metabolic processGO:00512531230.015
actin cytoskeleton organizationGO:0030036730.015
regulation of protein import into nucleusGO:0042306240.015
myelinationGO:0042552390.015
proteolysisGO:00065081750.015
regulation of cell migrationGO:00303341280.015
purine nucleoside metabolic processGO:00422781690.015
chemosensory behaviorGO:000763520.015
monocarboxylic acid metabolic processGO:00327871520.015
response to external biotic stimulusGO:00432072210.015
regulation of ion transmembrane transportGO:00347651210.015
sexual reproductionGO:00199531480.015
cellular component biogenesisGO:00440853680.015
Rat
metal ion homeostasisGO:00550651860.015
ensheathment of neuronsGO:0007272400.015
peptidyl amino acid modificationGO:00181931260.015
hormone transportGO:00099141210.015
response to transition metal nanoparticleGO:19902671220.015
ribonucleotide metabolic processGO:00092592310.015
axon ensheathmentGO:0008366400.014
g protein coupled receptor signaling pathwayGO:00071862420.014
organic substance catabolic processGO:19015753160.014
regulation of cellular component movementGO:00512701500.014
inflammatory responseGO:00069541500.014
carboxylic acid transportGO:00469421150.014
sequestering of metal ionGO:005123890.014
cell growthGO:00160491040.014
single organism nuclear importGO:1902593350.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
positive regulation of rna metabolic processGO:00512542030.014
choline transportGO:001587140.014
positive regulation of growthGO:0045927550.014
gonad developmentGO:00084061040.014
protein importGO:0017038370.014
response to molecule of bacterial originGO:00022371940.014
positive regulation of ion transportGO:0043270940.014
positive regulation of nucleotide metabolic processGO:0045981910.014
hormone metabolic processGO:0042445690.014
cellular catabolic processGO:00442482950.014
negative regulation of macromolecule metabolic processGO:00106052600.014
cellular carbohydrate metabolic processGO:0044262720.014
organic acid biosynthetic processGO:0016053830.014
monovalent inorganic cation transportGO:00156721720.013
cell motilityGO:00488702020.013
female sex differentiationGO:0046660590.013
positive regulation of cell proliferationGO:00082842490.013
embryonic skeletal system developmentGO:004870630.013
female pregnancyGO:00075651220.013
single organism membrane organizationGO:0044802740.013
sex differentiationGO:00075481130.013
purine ribonucleotide metabolic processGO:00091502270.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
negative regulation of biosynthetic processGO:00098901680.013
regulation of erk1 and erk2 cascadeGO:0070372410.013
glycosyl compound metabolic processGO:19016571820.013
regulation of growthGO:00400081050.013
retina morphogenesis in camera type eyeGO:006004210.013
purine nucleoside catabolic processGO:00061521240.013
negative regulation of nervous system developmentGO:0051961790.013
developmental process involved in reproductionGO:00030061590.013
nucleoside triphosphate metabolic processGO:00091411440.013
response to acid chemicalGO:00011012220.013
response to mechanical stimulusGO:00096121340.013
positive regulation of programmed cell deathGO:00430681570.013
cellular nitrogen compound catabolic processGO:00442701630.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
carbohydrate derivative catabolic processGO:19011361470.013
negative regulation of neuron deathGO:1901215690.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
cellular component maintenanceGO:004395440.013
dephosphorylationGO:0016311980.013
response to toxic substanceGO:00096361330.012
Rat
nucleobase containing compound catabolic processGO:00346551520.012
positive regulation of rna biosynthetic processGO:19026801970.012
protein localization to nucleusGO:0034504390.012
phospholipid metabolic processGO:0006644610.012
neurotransmitter gated ion channel clusteringGO:007257830.012
reproductive system developmentGO:00614581280.012
axis specificationGO:000979840.012
regulation of purine nucleotide metabolic processGO:19005421150.012
regulation of exocytosisGO:0017157370.012
organic cyclic compound catabolic processGO:19013611750.012
inorganic cation transmembrane transportGO:00986622020.012
negative regulation of homeostatic processGO:0032845470.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
peptidyl tyrosine modificationGO:0018212720.012
peptide transportGO:0015833970.012
positive regulation of secretion by cellGO:19035321280.012
rho protein signal transductionGO:0007266110.012
response to monosaccharideGO:00342841590.012
heart developmentGO:0007507720.012
regulation of protein targetingGO:1903533280.012
salivary gland developmentGO:000743130.012
positive regulation of nucleotide catabolic processGO:0030813530.012
negative regulation of secretionGO:0051048820.012
aromatic compound catabolic processGO:00194391680.012
response to hexoseGO:00097461440.012
ribonucleoside triphosphate catabolic processGO:00092031220.011
gliogenesisGO:0042063930.011
positive regulation of locomotionGO:00400171020.011
regulation of cell motilityGO:20001451310.011
dicarboxylic acid metabolic processGO:0043648420.011
ovulation cycleGO:0042698670.011
sodium ion transportGO:0006814820.011
regulation of intracellular transportGO:0032386650.011
negative regulation of cell communicationGO:00106481580.011
response to lipopolysaccharideGO:00324961910.011
positive regulation of cellular component biogenesisGO:0044089550.011
positive regulation of synaptic vesicle exocytosisGO:200030230.011
positive regulation of lipid metabolic processGO:0045834330.011
regulation of neuron projection developmentGO:00109751610.011
camera type eye morphogenesisGO:004859320.011
behaviorGO:00076102050.011
response to oxidative stressGO:00069791860.011
response to estradiolGO:00323551640.011
organonitrogen compound biosynthetic processGO:19015661670.011
carboxylic acid biosynthetic processGO:0046394830.011
cation homeostasisGO:00550801950.011
jak stat cascadeGO:0007259260.011
response to fluorideGO:190261730.011
spindle organizationGO:000705120.011
nucleoside phosphate catabolic processGO:19012921400.011
tissue developmentGO:00098882520.011
forebrain developmentGO:0030900980.011
positive regulation of cellular catabolic processGO:0031331710.011
cell projection morphogenesisGO:00488581230.011
circadian rhythmGO:0007623880.011
chromosome segregationGO:000705920.011
response to temperature stimulusGO:0009266940.011
cellular response to extracellular stimulusGO:0031668730.011
regulation of cellular catabolic processGO:00313291010.011
negative regulation of synaptic transmission glutamatergicGO:005196780.011
lipid localizationGO:0010876620.011
regulation of catabolic processGO:00098941130.011
cellular response to organic cyclic compoundGO:00714072020.011
negative regulation of cellular component organizationGO:0051129830.011
organonitrogen compound catabolic processGO:19015651790.010
protein targeting to nucleusGO:0044744350.010
positive regulation of dendrite developmentGO:1900006350.010
heart morphogenesisGO:000300730.010
peptide secretionGO:0002790860.010
regulation of nucleocytoplasmic transportGO:0046822280.010
development of primary sexual characteristicsGO:00451371070.010
neuron neuron synaptic transmissionGO:0007270600.010
exocytosisGO:0006887600.010
organic acid transportGO:00158491160.010
positive regulation of protein serine threonine kinase activityGO:0071902520.010
sensory organ developmentGO:0007423740.010
dna metabolic processGO:0006259960.010
cell part morphogenesisGO:00329901230.010
establishment of protein localization to organelleGO:0072594440.010
regulation of cell growthGO:0001558850.010
regulation of body fluid levelsGO:0050878900.010
regulation of lipid biosynthetic processGO:0046890380.010
feeding behaviorGO:0007631530.010
ribonucleoside catabolic processGO:00424541260.010
negative regulation of catalytic activityGO:00430861030.010
response to vitaminGO:00332731310.010
purine nucleotide catabolic processGO:00061951360.010
regulation of peptide hormone secretionGO:0090276800.010
purine ribonucleoside catabolic processGO:00461301240.010
single organism organelle organizationGO:19025891800.010
cell activationGO:0001775970.010

Grik2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.034
disease of anatomical entityDOID:700.034
epilepsy syndromeDOID:182600.034
brain diseaseDOID:93600.034
nervous system diseaseDOID:86300.034