Rattus norvegicus

10 known processes

Grik4

glutamate receptor, ionotropic, kainate 4

(Aliases: KA1)

Grik4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic anion transportGO:00157111320.148
protein complex assemblyGO:00064612630.140
macromolecular complex subunit organizationGO:00439333390.135
protein oligomerizationGO:00512591910.131
cellular response to endogenous stimulusGO:00714953770.124
central nervous system developmentGO:00074173110.119
cellular component assemblyGO:00226073600.117
multicellular organism reproductionGO:00325042330.117
programmed cell deathGO:00125013920.111
Rat
neurological system processGO:00508772190.107
organelle organizationGO:00069962660.105
cellular response to hormone stimulusGO:00328702470.104
cell cell signalingGO:00072673350.098
Rat
macromolecular complex assemblyGO:00650032730.098
g protein coupled receptor signaling pathwayGO:00071862420.097
regulation of signal transductionGO:00099663180.097
regulation of cell differentiationGO:00455953200.088
regulation of multicellular organismal developmentGO:20000263760.087
carboxylic acid transportGO:00469421150.084
single organism organelle organizationGO:19025891800.083
single organism behaviorGO:00447081300.079
nitrogen compound transportGO:00717052290.076
regulation of nucleic acid templated transcriptionGO:19035063800.075
synaptic transmissionGO:00072682350.073
Rat
regulation of neurogenesisGO:00507672470.071
rna metabolic processGO:00160704060.071
cellular component biogenesisGO:00440853680.070
cation transmembrane transportGO:00986552630.070
Rat
negative regulation of signalingGO:00230571570.068
Rat
reproductionGO:00000032450.066
regulation of anatomical structure morphogenesisGO:00226031410.063
head developmentGO:00603222470.063
cellular response to lipidGO:00713962010.062
transcription dna templatedGO:00063513770.062
negative regulation of nervous system developmentGO:0051961790.061
regulation of membrane potentialGO:00423911100.060
regulation of phosphate metabolic processGO:00192203490.058
organic acid metabolic processGO:00060822920.058
negative regulation of cell developmentGO:0010721820.056
positive regulation of cell communicationGO:00106472710.056
Rat
regulation of neurotransmitter levelsGO:0001505420.054
rna biosynthetic processGO:00327743800.054
response to growth factorGO:00708481890.053
reproductive processGO:00224143720.053
cellular response to acid chemicalGO:0071229750.053
brain developmentGO:00074202470.052
secretionGO:00469033070.052
negative regulation of multicellular organismal processGO:00512412030.051
mapk cascadeGO:00001651400.051
negative regulation of cellular metabolic processGO:00313242810.050
negative regulation of apoptotic processGO:00430661810.050
dicarboxylic acid transportGO:0006835340.050
single organism reproductive processGO:00447022970.049
organophosphate metabolic processGO:00196373700.047
negative regulation of cell communicationGO:00106481580.047
Rat
monovalent inorganic cation transportGO:00156721720.046
cellular response to oxygen containing compoundGO:19017013860.046
Rat
oxoacid metabolic processGO:00434362900.046
nucleoside phosphate metabolic processGO:00067532830.046
protein autophosphorylationGO:0046777660.046
nucleotide metabolic processGO:00091172790.043
cellular response to nitrogen compoundGO:19016992100.043
cellular response to growth factor stimulusGO:00713631620.043
cation transportGO:00068123820.043
Rat
learning or memoryGO:0007611900.043
protein phosphorylationGO:00064683450.042
multi organism reproductive processGO:00447032620.042
ion transmembrane transportGO:00342203650.042
Rat
regulation of phosphorylationGO:00423252480.041
regulation of cellular component organizationGO:00511283680.041
cell projection organizationGO:00300303020.041
regulation of transcription dna templatedGO:00063553740.040
cellular response to peptideGO:19016531330.040
nucleic acid templated transcriptionGO:00976593790.039
cell type specific apoptotic processGO:00972851340.039
Rat
action potentialGO:0001508540.038
negative regulation of transportGO:00510511360.038
regulation of neuron differentiationGO:00456642080.038
amino acid transportGO:0006865700.038
regulation of cell developmentGO:00602842630.038
regulation of programmed cell deathGO:00430673410.037
Rat
cellular calcium ion homeostasisGO:00068741600.037
calcium ion homeostasisGO:00550741620.037
regulation of secretion by cellGO:19035302080.037
transmembrane transportGO:00550854120.037
Rat
positive regulation of protein phosphorylationGO:00019341350.037
protein complex subunit organizationGO:00718223020.036
homeostatic processGO:00425923310.036
Rat
negative regulation of macromolecule metabolic processGO:00106052600.036
regulation of nervous system developmentGO:00519602640.036
regulation of rna biosynthetic processGO:20011413810.035
negative regulation of metabolic processGO:00098923310.035
multicellular organismal signalingGO:0035637440.035
negative regulation of neurogenesisGO:0050768780.035
positive regulation of signalingGO:00230562700.035
Rat
neuron differentiationGO:00301823680.034
negative regulation of neuron differentiationGO:0045665620.034
protein localizationGO:00081041910.034
Rat
regulation of protein metabolic processGO:00512462890.034
negative regulation of programmed cell deathGO:00430691830.033
negative regulation of cell differentiationGO:0045596990.033
neurotransmitter transportGO:0006836420.033
choline transportGO:001587140.033
purine containing compound metabolic processGO:00725212530.033
positive regulation of phosphorus metabolic processGO:00105622620.033
regulation of mapk cascadeGO:00434081160.032
transmission of nerve impulseGO:0019226420.032
response to peptideGO:19016522920.032
regulation of phosphorus metabolic processGO:00511743490.031
sexual reproductionGO:00199531480.031
metal ion transportGO:00300012890.030
positive regulation of protein metabolic processGO:00512471780.030
regulation of neuron projection developmentGO:00109751610.030
positive regulation of rna biosynthetic processGO:19026801970.030
developmental process involved in reproductionGO:00030061590.030
regulation of cellular protein metabolic processGO:00322682670.030
neuron developmentGO:00486662860.029
cellular amine metabolic processGO:0044106380.029
regulation of rna metabolic processGO:00512523910.029
response to inorganic substanceGO:00100353770.029
catabolic processGO:00090563510.029
cellular catabolic processGO:00442482950.029
carbohydrate derivative metabolic processGO:19011353460.029
cellular chemical homeostasisGO:00550822470.029
Rat
cellular response to organonitrogen compoundGO:00714171970.028
response to glucocorticoidGO:00513842230.028
inorganic ion transmembrane transportGO:00986602290.028
response to decreased oxygen levelsGO:00362932370.028
positive regulation of neurogenesisGO:00507691650.028
organic substance catabolic processGO:19015753160.028
anion transportGO:00068201780.028
regulation of amino acid transportGO:0051955250.028
positive regulation of phosphorylationGO:00423271770.028
response to oxygen levelsGO:00704822650.027
positive regulation of nervous system developmentGO:00519621780.027
positive regulation of cell deathGO:00109421840.027
Rat
organophosphate catabolic processGO:00464341480.027
negative regulation of cellular biosynthetic processGO:00313271610.027
neurotransmitter secretionGO:0007269330.026
regulation of cell projection organizationGO:00313441750.026
regulation of cell proliferationGO:00421273590.026
protein complex biogenesisGO:00702712630.026
ribonucleotide metabolic processGO:00092592310.026
regulation of organic acid transportGO:0032890350.025
regulation of molecular functionGO:00650093980.025
multicellular organismal reproductive processGO:00486092330.025
amine metabolic processGO:0009308380.025
cognitionGO:0050890920.025
organic acid transportGO:00158491160.024
regulation of canonical wnt signaling pathwayGO:006082840.024
regulation of protein phosphorylationGO:00019321830.024
cellular amino acid metabolic processGO:00065201070.024
positive regulation of cell developmentGO:00107201760.024
negative regulation of biosynthetic processGO:00098901680.024
proteolysisGO:00065081750.024
gamete generationGO:00072761240.024
transcription from rna polymerase ii promoterGO:00063662520.023
negative regulation of cell deathGO:00605482290.023
acid secretionGO:0046717480.023
behaviorGO:00076102050.023
activation of protein kinase activityGO:0032147470.023
positive regulation of cellular protein metabolic processGO:00322701670.023
positive regulation of gene expressionGO:00106282440.023
agingGO:00075682410.023
learningGO:0007612330.023
purine ribonucleotide metabolic processGO:00091502270.023
chemical homeostasisGO:00488782920.022
Rat
actin filament based processGO:0030029860.022
response to hypoxiaGO:00016662310.022
signal transduction by phosphorylationGO:00230141440.022
gliogenesisGO:0042063930.022
negative regulation of signal transductionGO:0009968830.022
cytoskeleton organizationGO:00070101110.022
regulation of anion transportGO:0044070430.022
ribonucleotide catabolic processGO:00092611360.022
adult locomotory behaviorGO:000834440.021
apoptotic processGO:00069153810.021
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.021
negative regulation of cellular component organizationGO:0051129830.021
regulation of protein kinase activityGO:00458591050.021
cellular nitrogen compound catabolic processGO:00442701630.021
response to extracellular stimulusGO:00099913800.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
positive regulation of developmental processGO:00510942830.021
single organism membrane organizationGO:0044802740.021
Rat
nucleobase containing small molecule metabolic processGO:00550863160.020
negative regulation of transcription dna templatedGO:00458921160.020
growthGO:00400071650.020
cell cycleGO:00070491010.020
purine nucleoside metabolic processGO:00422781690.020
positive regulation of protein kinase activityGO:0045860730.020
negative regulation of response to stimulusGO:00485851550.020
positive regulation of nucleotide metabolic processGO:0045981910.019
phototransduction visible lightGO:000760320.019
muscle system processGO:00030121150.019
memoryGO:0007613540.019
regulation of cellular amino acid metabolic processGO:000652120.019
regulation of hydrolase activityGO:00513361430.019
neural crest cell differentiationGO:001403320.019
protein heterooligomerizationGO:0051291890.019
nucleobase containing compound catabolic processGO:00346551520.019
neuron projection developmentGO:00311752730.018
anatomical structure morphogenesisGO:00096532980.018
regulation of cellular localizationGO:00603412630.018
anion transmembrane transportGO:0098656770.018
regulation of ion transportGO:00432692450.018
Rat
synaptic growth at neuromuscular junctionGO:005112410.018
positive regulation of signal transductionGO:00099671750.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
endocytosisGO:0006897840.018
regulation of cellular amine metabolic processGO:003323880.018
cytosolic calcium ion homeostasisGO:00514801400.018
positive regulation of cell proliferationGO:00082842490.017
potassium ion transportGO:0006813970.017
hair cycle processGO:002240520.017
ribose phosphate metabolic processGO:00196932350.017
secretion by cellGO:00329402480.017
actin cytoskeleton organizationGO:0030036730.017
glycosyl compound metabolic processGO:19016571820.017
regulation of intracellular signal transductionGO:19025312180.017
amide transportGO:00428861050.017
vesicle mediated transportGO:00161921810.017
aromatic compound catabolic processGO:00194391680.017
organ morphogenesisGO:0009887750.017
response to acid chemicalGO:00011012220.016
eye morphogenesisGO:004859240.016
gtp catabolic processGO:0006184710.016
positive regulation of rna metabolic processGO:00512542030.016
glial cell differentiationGO:0010001650.016
gonad developmentGO:00084061040.016
divalent inorganic cation homeostasisGO:00725071650.016
positive regulation of apoptotic processGO:00430651540.016
Rat
organic hydroxy compound metabolic processGO:19016151150.016
response to corticosteroidGO:00319602350.016
cellular cation homeostasisGO:00300031800.016
intracellular signal transductionGO:00355563140.016
positive regulation of kinase activityGO:0033674770.016
positive regulation of cell differentiationGO:00455972170.016
cell matrix adhesionGO:0007160190.016
detection of visible lightGO:000958430.016
regulation of apoptotic processGO:00429813350.016
Rat
regulation of kinase activityGO:00435491170.015
positive regulation of transcription dna templatedGO:00458931970.015
neuronal action potentialGO:0019228350.015
negative regulation of developmental processGO:00510931250.015
positive regulation of neuron projection developmentGO:0010976990.015
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
single organism catabolic processGO:00447122830.015
nucleoside phosphate catabolic processGO:19012921400.015
positive regulation of neuron differentiationGO:00456661260.015
response to estradiolGO:00323551640.015
purine containing compound catabolic processGO:00725231380.015
positive regulation of mapk cascadeGO:0043410920.015
positive regulation of biosynthetic processGO:00098913190.015
multicellular organismal homeostasisGO:0048871490.015
regulation of vesicle mediated transportGO:0060627810.015
cellular response to organic cyclic compoundGO:00714072020.015
regulation of dendrite developmentGO:0050773590.015
negative regulation of phosphate metabolic processGO:0045936800.014
regulation of protein modification processGO:00313991940.014
carbohydrate derivative catabolic processGO:19011361470.014
negative regulation of phosphorus metabolic processGO:0010563800.014
cellular homeostasisGO:00197252520.014
Rat
cellular response to stressGO:00335542690.014
positive regulation of molecular functionGO:00440932300.014
sex differentiationGO:00075481130.014
regulation of synaptic transmissionGO:00508041410.014
Rat
signal releaseGO:00230611450.014
carboxylic acid metabolic processGO:00197522890.014
negative regulation of gene expressionGO:00106291990.014
nucleotide catabolic processGO:00091661390.014
regulation of neural precursor cell proliferationGO:2000177160.014
inner ear receptor cell differentiationGO:006011320.014
regulation of cellular ketone metabolic processGO:0010565270.014
mechanoreceptor differentiationGO:004249020.013
protein modification by small protein conjugation or removalGO:0070647350.013
neural crest cell developmentGO:001403220.013
positive regulation of protein modification processGO:00314011420.013
neural crest cell migrationGO:000175510.013
negative regulation of neuron apoptotic processGO:0043524450.013
macromolecule localizationGO:00330362520.013
Rat
ion homeostasisGO:00508012120.013
nucleoside metabolic processGO:00091161790.013
hair follicle developmentGO:000194220.013
organic cyclic compound catabolic processGO:19013611750.013
cellular metal ion homeostasisGO:00068751720.013
negative regulation of neuron projection developmentGO:0010977460.013
sensory perceptionGO:00076001010.013
heart morphogenesisGO:000300730.013
cellular ketone metabolic processGO:0042180510.013
cell cell signaling involved in cell fate commitmentGO:004516820.013
ossificationGO:0001503700.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
reproductive system developmentGO:00614581280.012
positive regulation of ion transportGO:0043270940.012
guanosine containing compound metabolic processGO:1901068740.012
neurotransmitter uptakeGO:000150430.012
organophosphate biosynthetic processGO:00904071430.012
alcohol metabolic processGO:0006066770.012
hepaticobiliary system developmentGO:0061008900.012
spermatogenesisGO:0007283990.012
amino acid transmembrane transportGO:0003333330.012
gastrulationGO:000736920.012
protein homooligomerizationGO:0051260910.012
axis specificationGO:000979840.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
muscle contractionGO:0006936880.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
positive regulation of cellular component organizationGO:00511302000.012
development of primary sexual characteristicsGO:00451371070.012
carbohydrate derivative biosynthetic processGO:19011371240.011
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011
fertilizationGO:000956630.011
response to cgmpGO:007030530.011
regulation of establishment of protein localizationGO:0070201690.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
regulation of cellular component biogenesisGO:0044087860.011
positive regulation of programmed cell deathGO:00430681570.011
Rat
positive regulation of secretionGO:00510471400.011
receptor mediated endocytosisGO:0006898420.011
positive regulation of transferase activityGO:0051347810.011
positive regulation of cellular amine metabolic processGO:003324030.011
regulation of purine nucleotide metabolic processGO:19005421150.011
response to hexoseGO:00097461440.011
Rat
ribonucleoside metabolic processGO:00091191740.011
axon ensheathmentGO:0008366400.011
purine ribonucleoside metabolic processGO:00461281680.011
male gamete generationGO:0048232990.011
tissue developmentGO:00098882520.011
negative regulation of secretion by cellGO:1903531720.011
negative regulation of protein metabolic processGO:00512481140.011
multicellular organism growthGO:003526410.011
nucleoside triphosphate catabolic processGO:00091431230.011
ras protein signal transductionGO:0007265290.011
positive regulation of cell projection organizationGO:00313461110.011
regulation of anatomical structure sizeGO:00900661350.011
cellular component morphogenesisGO:00329891550.011
l glutamate importGO:005193820.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
female sex differentiationGO:0046660590.010
peptide transportGO:0015833970.010
hormone transportGO:00099141210.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
male gonad developmentGO:0008584590.010
positive regulation of amino acid transportGO:0051957130.010
establishment of planar polarityGO:000173610.010
purine nucleotide metabolic processGO:00061632290.010
organonitrogen compound catabolic processGO:19015651790.010
ensheathment of neuronsGO:0007272400.010
negative regulation of secretionGO:0051048820.010
divalent inorganic cation transportGO:00725111340.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010

Grik4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.085
nervous system diseaseDOID:86300.085
sensory system diseaseDOID:005015500.037
eye and adnexa diseaseDOID:149200.022
retinal diseaseDOID:567900.022
eye diseaseDOID:561400.022
retinal degenerationDOID:846600.018
central nervous system diseaseDOID:33100.015
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
disease of cellular proliferationDOID:1456600.010