Rattus norvegicus

89 known processes

Grik5

glutamate receptor, ionotropic, kainate 5

(Aliases: iGlu5)

Grik5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic growth at neuromuscular junctionGO:005112410.268
apoptotic processGO:00069153810.214
regulation of rna biosynthetic processGO:20011413810.188
secretion by cellGO:00329402480.142
regulation of synaptic growth at neuromuscular junctionGO:000858210.135
synapse organizationGO:0050808460.128
programmed cell deathGO:00125013920.122
neuron differentiationGO:00301823680.119
response to oxygen levelsGO:00704822650.117
protein autophosphorylationGO:0046777660.116
cell projection organizationGO:00300303020.106
neurological system processGO:00508772190.106
regulation of cellular protein metabolic processGO:00322682670.101
regulation of phosphorus metabolic processGO:00511743490.100
negative regulation of cellular metabolic processGO:00313242810.095
catabolic processGO:00090563510.094
regulation of signal transductionGO:00099663180.092
macromolecule localizationGO:00330362520.092
regulation of programmed cell deathGO:00430673410.092
cellular component morphogenesisGO:00329891550.090
positive regulation of signalingGO:00230562700.090
Rat
cellular component biogenesisGO:00440853680.089
organophosphate metabolic processGO:00196373700.089
organic acid metabolic processGO:00060822920.085
cellular catabolic processGO:00442482950.084
regulation of molecular functionGO:00650093980.082
reproductionGO:00000032450.081
response to inorganic substanceGO:00100353770.081
negative regulation of cell communicationGO:00106481580.081
Rat
growthGO:00400071650.079
regulation of apoptotic processGO:00429813350.079
response to extracellular stimulusGO:00099913800.079
reproductive processGO:00224143720.079
single organism biosynthetic processGO:00447113420.078
regulation of multicellular organismal developmentGO:20000263760.074
response to hexoseGO:00097461440.074
carboxylic acid metabolic processGO:00197522890.073
regulation of cellular localizationGO:00603412630.072
regulation of transcription dna templatedGO:00063553740.072
cellular response to oxygen containing compoundGO:19017013860.068
single organism catabolic processGO:00447122830.066
protein localizationGO:00081041910.066
lipid metabolic processGO:00066292830.065
regulation of cellular component organizationGO:00511283680.065
peptidyl amino acid modificationGO:00181931260.064
anterior posterior pattern specificationGO:000995210.064
regulation of cell proliferationGO:00421273590.064
nucleobase containing small molecule metabolic processGO:00550863160.062
regulation of secretionGO:00510462240.062
locomotionGO:00400112370.062
multi organism reproductive processGO:00447032620.062
synaptic transmissionGO:00072682350.061
positive regulation of gene expressionGO:00106282440.060
response to cytokineGO:00340972150.059
nitrogen compound transportGO:00717052290.059
cellular amino acid metabolic processGO:00065201070.059
positive regulation of molecular functionGO:00440932300.058
positive regulation of signal transductionGO:00099671750.058
regulation of cellular amine metabolic processGO:003323880.058
oxoacid metabolic processGO:00434362900.058
positive regulation of cell communicationGO:00106472710.058
Rat
neuron deathGO:00709971270.057
signal releaseGO:00230611450.057
rna biosynthetic processGO:00327743800.057
protein phosphorylationGO:00064683450.057
regulation of phosphate metabolic processGO:00192203490.056
regulation of neuron deathGO:19012141150.056
negative regulation of signalingGO:00230571570.056
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.054
regulation of kinase activityGO:00435491170.054
positive regulation of response to stimulusGO:00485842850.054
rna metabolic processGO:00160704060.054
male mating behaviorGO:006017930.054
cellular component assemblyGO:00226073600.054
cellular response to endogenous stimulusGO:00714953770.054
nucleoside phosphate metabolic processGO:00067532830.053
carbohydrate metabolic processGO:00059751300.053
regulation of neuron differentiationGO:00456642080.053
cell morphogenesis involved in differentiationGO:00009041190.052
positive regulation of multicellular organismal processGO:00512403870.052
cell cell signalingGO:00072673350.052
developmental process involved in reproductionGO:00030061590.051
cellular response to hormone stimulusGO:00328702470.051
response to nutrientGO:00075842480.050
cognitionGO:0050890920.050
head developmentGO:00603222470.050
regulation of nervous system developmentGO:00519602640.050
negative regulation of transportGO:00510511360.050
transcription dna templatedGO:00063513770.050
response to metal ionGO:00100382530.049
positive regulation of nitrogen compound metabolic processGO:00511733340.048
regulation of catalytic activityGO:00507903040.048
response to monosaccharideGO:00342841590.048
carbohydrate derivative metabolic processGO:19011353460.048
negative regulation of macromolecule metabolic processGO:00106052600.048
positive regulation of developmental processGO:00510942830.047
protein complex biogenesisGO:00702712630.047
nucleotide metabolic processGO:00091172790.046
single organism carbohydrate metabolic processGO:00447231180.046
developmental growthGO:00485891000.045
single organism reproductive processGO:00447022970.045
amine metabolic processGO:0009308380.044
multicellular organism reproductionGO:00325042330.044
macromolecular complex assemblyGO:00650032730.044
cell type specific apoptotic processGO:00972851340.044
positive regulation of cell deathGO:00109421840.044
multicellular organismal reproductive processGO:00486092330.043
negative regulation of metabolic processGO:00098923310.043
regulation of phosphorylationGO:00423252480.043
regulation of rna metabolic processGO:00512523910.043
regulation of vesicle mediated transportGO:0060627810.043
positive regulation of synapse maturationGO:009012920.042
response to ethanolGO:00454711620.042
regulation of ion transportGO:00432692450.042
Rat
negative regulation of response to stimulusGO:00485851550.042
transmembrane transportGO:00550854120.042
regulation of system processGO:00440572080.042
cellular amine metabolic processGO:0044106380.041
anatomical structure morphogenesisGO:00096532980.041
cellular component movementGO:00069282480.041
neuron developmentGO:00486662860.041
regulation of synapse maturationGO:009012820.041
positive regulation of phosphorylationGO:00423271770.041
regulation of endocytosisGO:0030100420.041
metal ion transportGO:00300012890.040
response to estrogenGO:00436272320.040
neuron apoptotic processGO:0051402880.040
regulation of intracellular signal transductionGO:19025312180.040
single organism organelle organizationGO:19025891800.040
response to decreased oxygen levelsGO:00362932370.040
monosaccharide metabolic processGO:0005996610.040
negative regulation of neuron apoptotic processGO:0043524450.039
divalent inorganic cation transportGO:00725111340.039
regulation of nucleic acid templated transcriptionGO:19035063800.039
positive regulation of cellular component organizationGO:00511302000.039
positive regulation of programmed cell deathGO:00430681570.039
regulation of synapse organizationGO:0050807190.039
intracellular signal transductionGO:00355563140.038
regulation of cell differentiationGO:00455953200.038
ionotropic glutamate receptor signaling pathwayGO:0035235340.038
organic substance catabolic processGO:19015753160.038
regulation of secretion by cellGO:19035302080.037
amide transportGO:00428861050.037
response to woundingGO:00096112540.037
single organism behaviorGO:00447081300.037
hormone transportGO:00099141210.037
negative regulation of biosynthetic processGO:00098901680.037
positive regulation of phosphorus metabolic processGO:00105622620.036
response to hypoxiaGO:00016662310.036
behaviorGO:00076102050.036
cellular response to peptideGO:19016531330.036
positive regulation of phosphate metabolic processGO:00459372620.036
homeostatic processGO:00425923310.035
chemical homeostasisGO:00488782920.035
regulation of peptide hormone secretionGO:0090276800.035
divalent metal ion transportGO:00708381320.035
response to carbohydrateGO:00097431830.034
proteolysisGO:00065081750.034
exocytosisGO:0006887600.034
regulation of protein metabolic processGO:00512462890.034
heterocycle catabolic processGO:00467001670.034
response to nutrient levelsGO:00316673700.033
regulation of proteasomal protein catabolic processGO:006113640.033
regulation of synaptic transmissionGO:00508041410.033
Rat
regulation of lipid metabolic processGO:0019216680.033
negative regulation of nucleobase containing compound metabolic processGO:00459341530.033
cellular ketone metabolic processGO:0042180510.033
negative regulation of cell deathGO:00605482290.032
secretionGO:00469033070.032
regenerationGO:00310991630.032
purine nucleotide metabolic processGO:00061632290.032
regulation of peptide secretionGO:0002791820.032
positive regulation of cell proliferationGO:00082842490.032
dendrite developmentGO:0016358720.031
regulation of developmental growthGO:0048638450.031
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
cellular lipid metabolic processGO:00442552080.031
negative regulation of signal transductionGO:0009968830.031
positive regulation of cellular amino acid metabolic processGO:004576410.031
cell morphogenesis involved in neuron differentiationGO:00486671060.031
negative regulation of gene expressionGO:00106291990.030
nucleic acid templated transcriptionGO:00976593790.030
ribose phosphate metabolic processGO:00196932350.030
cell migrationGO:00164771970.030
regulation of cellular amino acid metabolic processGO:000652120.029
glycosyl compound metabolic processGO:19016571820.029
ribonucleotide metabolic processGO:00092592310.029
peptide transportGO:0015833970.029
positive regulation of nervous system developmentGO:00519621780.029
gland developmentGO:00487321550.029
negative regulation of cellular biosynthetic processGO:00313271610.029
axon developmentGO:0061564960.029
response to glucoseGO:00097491360.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
response to acid chemicalGO:00011012220.028
cellular response to organonitrogen compoundGO:00714171970.028
myelinationGO:0042552390.028
single organism cellular localizationGO:19025801020.028
establishment of protein localizationGO:00451841410.028
regulation of cell cycleGO:0051726730.028
protein complex subunit organizationGO:00718223020.028
purine containing compound catabolic processGO:00725231380.028
organonitrogen compound biosynthetic processGO:19015661670.028
negative regulation of nucleic acid templated transcriptionGO:19035071170.028
regulation of neurogenesisGO:00507672470.028
regulation of cell morphogenesis involved in differentiationGO:0010769720.028
neuron projection developmentGO:00311752730.027
reproductive system developmentGO:00614581280.027
regulation of peptide transportGO:0090087870.027
axon ensheathmentGO:0008366400.027
protein oligomerizationGO:00512591910.027
positive regulation of cellular amine metabolic processGO:003324030.027
regulation of growthGO:00400081050.027
positive regulation of biosynthetic processGO:00098913190.027
peptidyl tyrosine phosphorylationGO:0018108720.026
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.026
purine ribonucleotide metabolic processGO:00091502270.026
epithelium developmentGO:0060429960.026
localization of cellGO:00516742020.026
response to peptide hormoneGO:00434342780.026
macromolecular complex subunit organizationGO:00439333390.026
regulation of neuron apoptotic processGO:0043523830.026
regulation of membrane potentialGO:00423911100.025
vesicle mediated transportGO:00161921810.025
response to ketoneGO:19016541820.025
regulation of cell growthGO:0001558850.025
negative regulation of secretionGO:0051048820.025
response to peptideGO:19016522920.025
tissue developmentGO:00098882520.025
microvillus assemblyGO:003003320.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
purine containing compound metabolic processGO:00725212530.024
central nervous system developmentGO:00074173110.024
gamete generationGO:00072761240.024
positive regulation of cellular biosynthetic processGO:00313282950.024
protein transportGO:00150311320.024
mitotic spindle organizationGO:000705220.024
response to external biotic stimulusGO:00432072210.024
negative regulation of apoptotic processGO:00430661810.024
aromatic compound catabolic processGO:00194391680.024
organophosphate biosynthetic processGO:00904071430.023
regulation of organelle organizationGO:0033043800.023
cell projection morphogenesisGO:00488581230.023
monocarboxylic acid metabolic processGO:00327871520.023
cellular response to stressGO:00335542690.023
cation transportGO:00068123820.023
Rat
small gtpase mediated signal transductionGO:0007264360.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
regulation of metal ion transportGO:00109591180.023
hormone secretionGO:00468791150.023
purine ribonucleoside triphosphate catabolic processGO:00092071220.023
cellular macromolecule localizationGO:00707271220.023
regulation of hormone levelsGO:00108171870.023
positive regulation of locomotionGO:00400171020.023
negative regulation of developmental processGO:00510931250.023
neuron projection morphogenesisGO:00488121220.023
regulation of catabolic processGO:00098941130.022
negative regulation of protein metabolic processGO:00512481140.022
organelle organizationGO:00069962660.022
negative regulation of transcription dna templatedGO:00458921160.022
positive regulation of protein modification processGO:00314011420.022
macromolecule catabolic processGO:0009057580.022
ion homeostasisGO:00508012120.022
oxidation reduction processGO:00551143040.022
action potentialGO:0001508540.022
learning or memoryGO:0007611900.022
brain developmentGO:00074202470.022
gliogenesisGO:0042063930.022
negative regulation of programmed cell deathGO:00430691830.022
glial cell differentiationGO:0010001650.022
regulation of protein kinase activityGO:00458591050.021
cell part morphogenesisGO:00329901230.021
peptidyl tyrosine modificationGO:0018212720.021
negative regulation of phosphate metabolic processGO:0045936800.021
peptide hormone secretionGO:0030072840.021
regulation of hormone secretionGO:00468831060.021
neurotransmitter secretionGO:0007269330.021
cell adhesionGO:00071551100.021
sexual reproductionGO:00199531480.021
reproductive structure developmentGO:00486081280.021
protein homooligomerizationGO:0051260910.021
olfactory behaviorGO:004204820.021
organophosphate catabolic processGO:00464341480.021
regulation of cellular component biogenesisGO:0044087860.021
protein complex assemblyGO:00064612630.021
regulation of cellular ketone metabolic processGO:0010565270.020
ras protein signal transductionGO:0007265290.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
mechanoreceptor differentiationGO:004249020.020
regulation of protein phosphorylationGO:00019321830.020
positive regulation of catalytic activityGO:00430851840.020
transmission of nerve impulseGO:0019226420.020
cellular response to nitrogen compoundGO:19016992100.020
establishment of synaptic vesicle localizationGO:0097480230.020
regulation of nucleotide metabolic processGO:00061401170.020
regulation of synapse assemblyGO:0051963150.020
tube developmentGO:0035295890.020
response to estradiolGO:00323551640.020
positive regulation of cell migrationGO:0030335960.019
response to temperature stimulusGO:0009266940.019
glycosyl compound catabolic processGO:19016581260.019
regulation of protein modification processGO:00313991940.019
multicellular organismal signalingGO:0035637440.019
response to purine containing compoundGO:00140741260.019
cell cycle checkpointGO:000007520.019
negative regulation of cellular protein metabolic processGO:00322691060.019
tissue regenerationGO:0042246360.019
regulation of establishment of protein localizationGO:0070201690.019
positive regulation of apoptotic processGO:00430651540.019
membrane organizationGO:0061024940.019
negative regulation of rna metabolic processGO:00512531230.018
development of primary sexual characteristicsGO:00451371070.018
response to mechanical stimulusGO:00096121340.018
cardiovascular system developmentGO:00723581340.018
vasculogenesisGO:000157030.018
olfactory learningGO:000835510.018
negative regulation of rna biosynthetic processGO:19026791180.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.018
calcium mediated signaling using intracellular calcium sourceGO:003558410.018
hexose metabolic processGO:0019318580.018
cellular response to insulin stimulusGO:0032869810.018
rhythmic processGO:00485111560.018
axis specificationGO:000979840.018
ribonucleoside catabolic processGO:00424541260.018
divalent inorganic cation homeostasisGO:00725071650.017
positive regulation of transportGO:00510502450.017
regulation of anatomical structure sizeGO:00900661350.017
establishment of vesicle localizationGO:0051650310.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
response to corticosteroidGO:00319602350.017
Rat
synaptic vesicle localizationGO:0097479240.017
positive regulation of neuron differentiationGO:00456661260.017
salivary gland developmentGO:000743130.017
protein localization to nucleusGO:0034504390.017
regulation of neuron projection developmentGO:00109751610.017
organelle localizationGO:0051640550.017
glucose metabolic processGO:0006006520.017
cellular homeostasisGO:00197252520.017
protein targetingGO:0006605610.017
cellular response to acid chemicalGO:0071229750.017
cell morphogenesisGO:00009021420.016
positive regulation of cell differentiationGO:00455972170.016
establishment of organelle localizationGO:0051656370.016
cellular chemical homeostasisGO:00550822470.016
embryonic pattern specificationGO:000988010.016
metal ion homeostasisGO:00550651860.016
positive regulation of intracellular signal transductionGO:19025331380.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
organonitrogen compound catabolic processGO:19015651790.016
negative regulation of multicellular organismal processGO:00512412030.016
phospholipid metabolic processGO:0006644610.016
regulation of purine nucleotide metabolic processGO:19005421150.016
positive regulation of organelle organizationGO:0010638480.016
positive regulation of protein phosphorylationGO:00019341350.016
sex differentiationGO:00075481130.016
cytoskeleton dependent cytokinesisGO:006164020.016
negative regulation of molecular functionGO:00440921330.016
response to oxidative stressGO:00069791860.016
positive regulation of neurogenesisGO:00507691650.016
generation of precursor metabolites and energyGO:0006091620.016
sodium ion transportGO:0006814820.016
cell growthGO:00160491040.016
synapse assemblyGO:0007416290.016
biological adhesionGO:00226101100.016
positive regulation of cell developmentGO:00107201760.016
single organism intracellular transportGO:19025821660.016
positive regulation of purine nucleotide metabolic processGO:1900544910.016
peptidyl serine phosphorylationGO:0018105330.016
single organism membrane organizationGO:0044802740.015
positive regulation of secretionGO:00510471400.015
muscle structure developmentGO:0061061870.015
inorganic cation transmembrane transportGO:00986622020.015
regulation of calcium ion transportGO:0051924770.015
neuron neuron synaptic transmissionGO:0007270600.015
Rat
regulation of homeostatic processGO:00328441010.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
sulfur compound metabolic processGO:0006790700.015
regulation of cell migrationGO:00303341280.015
cellular nitrogen compound catabolic processGO:00442701630.015
gastrulationGO:000736920.015
nucleoside triphosphate catabolic processGO:00091431230.015
response to fatty acidGO:0070542650.015
smooth muscle cell proliferationGO:0048659770.015
immune responseGO:00069551040.015
response to other organismGO:00517072200.015
gonad developmentGO:00084061040.015
response to molecule of bacterial originGO:00022371940.015
cell cell signaling involved in cell fate commitmentGO:004516820.015
cellular response to peptide hormone stimulusGO:00713751200.015
spindle organizationGO:000705120.015
comma shaped body morphogenesisGO:007204920.015
glycerolipid metabolic processGO:0046486670.015
regulation of anatomical structure morphogenesisGO:00226031410.015
regulation of cell developmentGO:00602842630.015
neuronal action potentialGO:0019228350.015
regulation of hydrolase activityGO:00513361430.015
negative regulation of cell proliferationGO:00082851190.015
purine ribonucleoside metabolic processGO:00461281680.014
renal system developmentGO:0072001670.014
ensheathment of neuronsGO:0007272400.014
chemosensory behaviorGO:000763520.014
insulin secretionGO:0030073690.014
negative regulation of nervous system developmentGO:0051961790.014
negative regulation of phosphorus metabolic processGO:0010563800.014
response to retinoic acidGO:0032526630.014
adult locomotory behaviorGO:000834440.014
axonogenesisGO:0007409710.014
regulation of mapk cascadeGO:00434081160.014
response to growth factorGO:00708481890.014
cellular protein localizationGO:00346131220.014
response to reactive oxygen speciesGO:00003021200.014
regulation of insulin secretionGO:0050796650.014
synaptic vesicle exocytosisGO:0016079150.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
positive regulation of synaptic transmissionGO:0050806620.014
Rat
regulation of dna metabolic processGO:0051052600.014
regulation of transferase activityGO:00513381230.013
regulation of cellular catabolic processGO:00313291010.013
intracellular transportGO:00469071850.013
cytoplasmic transportGO:00164821150.013
conditioned taste aversionGO:000166120.013
positive regulation of secretion by cellGO:19035321280.013
sequestering of metal ionGO:005123890.013
embryo developmentGO:0009790490.013
protein import into nucleusGO:0006606350.013
camp metabolic processGO:0046058630.013
positive regulation of transcription dna templatedGO:00458931970.013
insulin like growth factor receptor signaling pathwayGO:004800930.013
regulation of fat cell differentiationGO:004559830.013
negative regulation of cellular component organizationGO:0051129830.013
wound healingGO:00420601220.013
ossificationGO:0001503700.013
response to amino acidGO:0043200750.013
signal transduction by phosphorylationGO:00230141440.013
formation of primary germ layerGO:000170410.013
regulation of cell projection organizationGO:00313441750.013
protein catabolic processGO:0030163300.013
regulation of synapse structure and activityGO:0050803210.013
rna localizationGO:000640340.013
sensory organ developmentGO:0007423740.013
cell cycleGO:00070491010.013
neuron fate commitmentGO:004866340.013
regulation of axonogenesisGO:0050770370.013
protein tetramerizationGO:0051262380.012
sequestering of calcium ionGO:005120880.012
glutamate receptor signaling pathwayGO:0007215430.012
nucleoside phosphate catabolic processGO:19012921400.012
vasculature developmentGO:0001944700.012
reactive oxygen species metabolic processGO:0072593370.012
positive regulation of cellular component movementGO:00512721020.012
positive regulation of protein metabolic processGO:00512471780.012
negative regulation of cell differentiationGO:0045596990.012
male gonad developmentGO:0008584590.012
response to vitaminGO:00332731310.012
negative regulation of secretion by cellGO:1903531720.012
response to organophosphorusGO:00466831020.012
organic cyclic compound catabolic processGO:19013611750.012
positive regulation of rna biosynthetic processGO:19026801970.012
energy derivation by oxidation of organic compoundsGO:0015980460.012
establishment of protein localization to organelleGO:0072594440.012
circulatory system processGO:00030131830.012
ribonucleotide catabolic processGO:00092611360.012
ribonucleoside metabolic processGO:00091191740.012
dna metabolic processGO:0006259960.012
activation of protein kinase b activityGO:003214830.012
positive regulation of kinase activityGO:0033674770.012
cell motilityGO:00488702020.012
synaptic vesicle endocytosisGO:004848840.012
cellular response to lipidGO:00713962010.012
purine nucleoside catabolic processGO:00061521240.012
ion transmembrane transportGO:00342203650.012
negative regulation of growthGO:0045926370.012
terminal button organizationGO:007255330.012
vesicle localizationGO:0051648330.012
agingGO:00075682410.012
response to campGO:0051591910.012
organic acid transportGO:00158491160.012
microtubule organizing center organizationGO:003102310.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
multi multicellular organism processGO:00447061380.011
negative regulation of catalytic activityGO:00430861030.011
cellular carbohydrate metabolic processGO:0044262720.011
synaptic vesicle transportGO:0048489230.011
positive regulation of lipid kinase activityGO:009021820.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
gtp metabolic processGO:0046039720.011
nuclear transportGO:0051169490.011
regulation of protein localizationGO:0032880810.011
response to toxic substanceGO:00096361330.011
blood circulationGO:00080151830.011

Grik5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.053
disease of anatomical entityDOID:700.053
central nervous system diseaseDOID:33100.017
parkinson s diseaseDOID:1433000.014
synucleinopathyDOID:005089000.014
neurodegenerative diseaseDOID:128900.014