Rattus norvegicus

77 known processes

Foxa2

forkhead box A2

(Aliases: Hnf3b)

Foxa2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to stressGO:00335542690.325
hepatocyte proliferationGO:007257430.250
response to extracellular stimulusGO:00099913800.237
Rat
response to peptideGO:19016522920.214
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.177
response to corticosteroidGO:00319602350.167
response to decreased oxygen levelsGO:00362932370.159
cellular response to organonitrogen compoundGO:00714171970.158
response to molecule of bacterial originGO:00022371940.156
protein complex subunit organizationGO:00718223020.155
response to bacteriumGO:00096172000.153
cellular response to endogenous stimulusGO:00714953770.150
cellular response to nitrogen compoundGO:19016992100.143
tissue developmentGO:00098882520.141
Human Rat
macromolecule localizationGO:00330362520.135
negative regulation of response to stimulusGO:00485851550.133
positive regulation of nitrogen compound metabolic processGO:00511733340.128
response to hypoxiaGO:00016662310.127
response to cytokineGO:00340972150.125
negative regulation of metabolic processGO:00098923310.121
Rat
positive regulation of cellular biosynthetic processGO:00313282950.118
organ regenerationGO:00311001010.118
negative regulation of cellular metabolic processGO:00313242810.115
Rat
rna metabolic processGO:00160704060.107
cellular response to cytokine stimulusGO:00713451270.105
response to nutrient levelsGO:00316673700.104
Rat
negative regulation of gene expressionGO:00106291990.103
Rat
negative regulation of multicellular organismal processGO:00512412030.100
Human
response to glucocorticoidGO:00513842230.099
response to peptide hormoneGO:00434342780.098
rna biosynthetic processGO:00327743800.098
cellular catabolic processGO:00442482950.094
cellular response to oxygen containing compoundGO:19017013860.090
cellular response to hormone stimulusGO:00328702470.089
behaviorGO:00076102050.086
reproductive processGO:00224143720.085
cellular response to steroid hormone stimulusGO:0071383930.085
response to glucoseGO:00097491360.085
regulation of reactive oxygen species metabolic processGO:2000377260.082
regulation of protein metabolic processGO:00512462890.079
response to monosaccharideGO:00342841590.079
acute inflammatory responseGO:0002526580.078
cellular response to external stimulusGO:00714961180.078
response to biotic stimulusGO:00096072260.077
negative regulation of biosynthetic processGO:00098901680.075
Rat
cellular response to peptide hormone stimulusGO:00713751200.075
regulation of cell differentiationGO:00455953200.074
Human Rat
carbohydrate homeostasisGO:0033500750.074
response to starvationGO:0042594590.073
macromolecular complex assemblyGO:00650032730.071
cellular response to corticosteroid stimulusGO:0071384690.070
negative regulation of phosphate metabolic processGO:0045936800.070
multi multicellular organism processGO:00447061380.067
regulation of extracellular matrix constituent secretionGO:000333020.067
regulation of ion transportGO:00432692450.066
negative regulation of nitrogen compound metabolic processGO:00511721610.065
Rat
regulation of cellular protein metabolic processGO:00322682670.065
positive regulation of transportGO:00510502450.064
response to other organismGO:00517072200.063
response to acid chemicalGO:00011012220.063
multi organism reproductive processGO:00447032620.063
cellular chemical homeostasisGO:00550822470.062
establishment of protein localizationGO:00451841410.062
vesicle mediated transportGO:00161921810.060
positive regulation of biosynthetic processGO:00098913190.059
central nervous system developmentGO:00074173110.059
negative regulation of phosphorus metabolic processGO:0010563800.059
secretion by cellGO:00329402480.058
positive regulation of extracellular matrix constituent secretionGO:000333120.058
regulation of phosphate metabolic processGO:00192203490.058
positive regulation of macromolecule biosynthetic processGO:00105572470.057
cellular amino acid metabolic processGO:00065201070.057
negative regulation of innate immune responseGO:004582440.057
cation transportGO:00068123820.056
metal ion transportGO:00300012890.056
response to lipopolysaccharideGO:00324961910.056
proteolysisGO:00065081750.055
response to oxygen levelsGO:00704822650.055
response to hexoseGO:00097461440.055
nucleic acid templated transcriptionGO:00976593790.055
regulation of cellular localizationGO:00603412630.054
cellular homeostasisGO:00197252520.054
reactive oxygen species metabolic processGO:0072593370.054
positive regulation of nucleobase containing compound metabolic processGO:00459353190.054
response to inorganic substanceGO:00100353770.053
homeostatic processGO:00425923310.052
anatomical structure morphogenesisGO:00096532980.052
Human
cellular component biogenesisGO:00440853680.052
cellular component assemblyGO:00226073600.052
single organism organelle organizationGO:19025891800.052
response to interleukin 1GO:0070555550.052
regulation of molecular functionGO:00650093980.051
Human
negative regulation of rna biosynthetic processGO:19026791180.051
Rat
response to woundingGO:00096112540.051
Human
protein complex biogenesisGO:00702712630.050
glucose homeostasisGO:0042593750.050
positive regulation of response to stimulusGO:00485842850.048
neuron developmentGO:00486662860.048
protein localizationGO:00081041910.048
lipid metabolic processGO:00066292830.048
regulation of anatomical structure morphogenesisGO:00226031410.047
Human
regulation of apoptotic processGO:00429813350.047
response to nutrientGO:00075842480.047
response to external biotic stimulusGO:00432072210.047
reproductionGO:00000032450.045
negative regulation of macromolecule metabolic processGO:00106052600.045
Rat
chemical homeostasisGO:00488782920.044
epithelial cell proliferation involved in liver morphogenesisGO:007257530.044
carboxylic acid metabolic processGO:00197522890.044
regulation of reactive oxygen species biosynthetic processGO:190342650.044
programmed cell deathGO:00125013920.044
divalent metal ion transportGO:00708381320.044
liver developmentGO:0001889900.044
Rat
regulation of transcription dna templatedGO:00063553740.044
response to hydrogen peroxideGO:0042542890.043
hepaticobiliary system developmentGO:0061008900.043
Rat
negative regulation of cellular biosynthetic processGO:00313271610.043
Rat
positive regulation of cell communicationGO:00106472710.043
male mating behaviorGO:006017930.042
negative regulation of serine type endopeptidase activityGO:190000410.042
cellular component morphogenesisGO:00329891550.041
Human
cellular response to lipidGO:00713962010.041
positive regulation of signalingGO:00230562700.041
negative regulation of macromolecule biosynthetic processGO:00105581480.041
Rat
negative regulation of immune system processGO:0002683390.041
transmission of nerve impulseGO:0019226420.040
cellular ketone metabolic processGO:0042180510.040
positive regulation of gene expressionGO:00106282440.039
divalent inorganic cation transportGO:00725111340.038
regulation of cellular amino acid metabolic processGO:000652120.038
response to carbohydrateGO:00097431830.038
synaptic transmissionGO:00072682350.038
regulation of neurogenesisGO:00507672470.038
regulation of rna biosynthetic processGO:20011413810.038
regulation of body fluid levelsGO:0050878900.038
Human
transcription dna templatedGO:00063513770.037
regulation of programmed cell deathGO:00430673410.037
cellular protein localizationGO:00346131220.037
circulatory system developmentGO:00723591340.037
positive regulation of extracellular matrix organizationGO:190305540.037
regulation of signal transductionGO:00099663180.037
positive regulation of coagulationGO:005082050.036
response to reactive oxygen speciesGO:00003021200.036
regulation of nervous system developmentGO:00519602640.036
organic acid metabolic processGO:00060822920.035
catabolic processGO:00090563510.035
negative regulation of nucleobase containing compound metabolic processGO:00459341530.035
Rat
protein phosphorylationGO:00064683450.035
regulation of response to stressGO:00801341260.035
Human
positive regulation of developmental processGO:00510942830.034
Rat
response to oxidative stressGO:00069791860.034
response to insulinGO:00328681330.034
cellular response to fluid shear stressGO:007149840.034
cellular response to peptideGO:19016531330.034
negative regulation of natural killer cell mediated immunityGO:000271640.033
regulation of cellular component organizationGO:00511283680.033
Human
cellular response to interleukin 1GO:0071347370.033
regulation of multicellular organismal developmentGO:20000263760.033
Human Rat
macromolecule catabolic processGO:0009057580.033
multicellular organism reproductionGO:00325042330.033
regulation of secretion by cellGO:19035302080.033
regulation of system processGO:00440572080.032
immune system processGO:00023762040.032
carbohydrate derivative metabolic processGO:19011353460.031
regulation of cellular ketone metabolic processGO:0010565270.031
secretionGO:00469033070.031
regulation of protein modification processGO:00313991940.031
signal releaseGO:00230611450.031
macromolecular complex subunit organizationGO:00439333390.031
response to ketoneGO:19016541820.030
oxidation reduction processGO:00551143040.030
reactive oxygen species biosynthetic processGO:190340980.030
regulation of cell proliferationGO:00421273590.030
Rat
store operated calcium entryGO:000211520.030
liver morphogenesisGO:007257630.030
cellular response to glucocorticoid stimulusGO:0071385680.030
positive regulation of rna biosynthetic processGO:19026801970.030
regenerationGO:00310991630.029
response to vitaminGO:00332731310.029
positive regulation of rna metabolic processGO:00512542030.029
protein secretionGO:0009306340.028
cellular amine metabolic processGO:0044106380.028
positive regulation of cellular component organizationGO:00511302000.028
regulation of catalytic activityGO:00507903040.028
positive regulation of phosphorylationGO:00423271770.028
regulation of phosphorus metabolic processGO:00511743490.028
response to estrogenGO:00436272320.028
immune responseGO:00069551040.028
positive regulation of multicellular organismal processGO:00512403870.027
Rat
extracellular matrix constituent secretionGO:007027840.027
neuron projection developmentGO:00311752730.027
negative regulation of apoptotic processGO:00430661810.027
neuron differentiationGO:00301823680.027
regulation of serine type endopeptidase activityGO:190000310.027
cell projection organizationGO:00300303020.027
response to transition metal nanoparticleGO:19902671220.027
positive regulation of cell developmentGO:00107201760.026
sex differentiationGO:00075481130.026
gland developmentGO:00487321550.026
Rat
oxoacid metabolic processGO:00434362900.026
negative regulation of rna metabolic processGO:00512531230.026
Rat
positive regulation of cellular amine metabolic processGO:003324030.026
positive regulation of nervous system developmentGO:00519621780.026
response to growth factorGO:00708481890.025
nitrogen compound transportGO:00717052290.025
negative regulation of response to external stimulusGO:0032102370.025
response to toxic substanceGO:00096361330.025
negative regulation of wound healingGO:006104580.025
cellular response to organic cyclic compoundGO:00714072020.024
innate immune responseGO:0045087350.024
transmembrane transportGO:00550854120.024
regulation of hormone levelsGO:00108171870.023
g protein coupled receptor signaling pathwayGO:00071862420.023
spermatogenesisGO:0007283990.023
circadian rhythmGO:0007623880.023
cell cell signalingGO:00072673350.023
cellular response to ammonium ionGO:0071242170.023
cell morphogenesisGO:00009021420.023
Human
response to corticosteroneGO:0051412400.023
regulation of rna metabolic processGO:00512523910.022
regulation of establishment of protein localizationGO:0070201690.022
epithelium developmentGO:0060429960.022
Rat
negative regulation of cell proliferationGO:00082851190.022
Rat
renal system processGO:0003014400.022
regulation of calcium ion transportGO:0051924770.022
cellular response to growth factor stimulusGO:00713631620.021
cardiovascular system developmentGO:00723581340.021
cholesterol homeostasisGO:004263230.021
coagulationGO:0050817280.021
Human
maternal process involved in female pregnancyGO:0060135380.021
single organism intracellular transportGO:19025821660.021
single organism biosynthetic processGO:00447113420.021
multicellular organism growthGO:003526410.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
positive regulation of reactive oxygen species metabolic processGO:2000379160.021
multicellular organismal reproductive processGO:00486092330.021
protein homooligomerizationGO:0051260910.021
sterol homeostasisGO:005509230.021
negative regulation of transcription dna templatedGO:00458921160.020
Rat
response to mineralocorticoidGO:0051385490.020
cytokine secretionGO:0050663150.020
negative regulation of molecular functionGO:00440921330.020
Human
organic substance catabolic processGO:19015753160.020
positive regulation of cell proliferationGO:00082842490.020
Rat
muscle contractionGO:0006936880.020
negative regulation of catalytic activityGO:00430861030.020
positive regulation of neuron differentiationGO:00456661260.020
phosphatidylinositol dephosphorylationGO:004685640.019
response to alkaloidGO:00432791320.019
positive regulation of cell projection organizationGO:00313461110.019
positive regulation of cell deathGO:00109421840.019
hemostasisGO:0007599260.019
Human
epithelial cell differentiationGO:0030855710.019
Rat
cellular response to hexose stimulusGO:0071331650.019
cerebellar purkinje cell layer developmentGO:002168020.019
calcium ion transportGO:00068161310.018
regulation of cellular amine metabolic processGO:003323880.018
response to fatty acidGO:0070542650.018
response to campGO:0051591910.018
positive regulation of cell differentiationGO:00455972170.018
Rat
regulation of phosphatidylinositol dephosphorylationGO:006030410.018
regulation of phosphorylationGO:00423252480.018
reproductive system developmentGO:00614581280.018
neurological system processGO:00508772190.018
regulation of cell projection organizationGO:00313441750.018
negative regulation of serine type peptidase activityGO:190257210.018
cellular response to reactive oxygen speciesGO:0034614550.018
inflammatory responseGO:00069541500.018
cellular response to glucose stimulusGO:0071333650.018
defecationGO:003042110.018
plasminogen activationGO:003163920.018
lipid biosynthetic processGO:00086101280.018
cation homeostasisGO:00550801950.018
positive regulation of cell migrationGO:0030335960.018
protein maturationGO:0051604680.018
regulation of protein transportGO:0051223680.018
dephosphorylationGO:0016311980.017
cellular response to oxidative stressGO:0034599760.017
cardiac conductionGO:006133720.017
protein oligomerizationGO:00512591910.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
Rat
positive regulation of neuron projection developmentGO:0010976990.017
intracellular transportGO:00469071850.017
cellular glucose homeostasisGO:0001678660.017
negative regulation of response to woundingGO:1903035230.017
organic hydroxy compound metabolic processGO:19016151150.017
regulation of serine type peptidase activityGO:190257110.017
multicellular organismal signalingGO:0035637440.017
female pregnancyGO:00075651220.017
positive regulation of apoptotic processGO:00430651540.017
metal ion homeostasisGO:00550651860.017
regulation of nucleic acid templated transcriptionGO:19035063800.017
response to organophosphorusGO:00466831020.017
biological adhesionGO:00226101100.017
positive regulation of protein phosphorylationGO:00019341350.017
cellular response to carbohydrate stimulusGO:0071322720.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
regulation of cell morphogenesisGO:0022604770.016
Human
cellular response to starvationGO:0009267270.016
cellular sodium ion homeostasisGO:000688340.016
regulation of cell developmentGO:00602842630.016
Human
protein complex assemblyGO:00064612630.016
response to muscle activity involved in regulation of muscle adaptationGO:001487320.016
positive regulation of secretion by cellGO:19035321280.016
protein transportGO:00150311320.016
response to chromateGO:004668730.016
androgen biosynthetic processGO:0006702100.016
positive regulation of neurogenesisGO:00507691650.016
cellular response to alcoholGO:0097306870.016
locomotionGO:00400112370.016
positive regulation of cellular protein metabolic processGO:00322701670.016
positive regulation of molecular functionGO:00440932300.016
amine metabolic processGO:0009308380.016
reactive nitrogen species metabolic processGO:200105710.016
cytoplasmic transportGO:00164821150.016
limbic system developmentGO:0021761380.015
protein homotrimerizationGO:0070207150.015
neuronal action potentialGO:0019228350.015
regulation of neuron projection developmentGO:00109751610.015
regulation of immune responseGO:0050776550.015
development of primary sexual characteristicsGO:00451371070.015
bile acid biosynthetic processGO:000669930.015
blood coagulationGO:0007596260.015
Human
single organism reproductive processGO:00447022970.015
regulation of secretionGO:00510462240.015
negative regulation of cytokine productionGO:0001818160.015
response to vitamin aGO:0033189360.015
regulation of protein processingGO:0070613500.015
apoptotic processGO:00069153810.015
response to metal ionGO:00100382530.015
sexual reproductionGO:00199531480.015
immune effector processGO:0002252530.015
organic hydroxy compound transportGO:0015850770.015
regulation of metal ion transportGO:00109591180.015
negative regulation of cellular component organizationGO:0051129830.015
Human
response to ammonium ionGO:0060359710.015
organ morphogenesisGO:0009887750.014
negative regulation of programmed cell deathGO:00430691830.014
regulation of cellular response to stressGO:0080135490.014
muscle system processGO:00030121150.014
negative regulation of cellular protein metabolic processGO:00322691060.014
pallium developmentGO:0021543420.014
response to activityGO:0014823730.014
regulation of intracellular signal transductionGO:19025312180.014
cell activationGO:0001775970.014
tube developmentGO:0035295890.014
neuron projection regenerationGO:0031102350.014
intracellular signal transductionGO:00355563140.014
cellular cation homeostasisGO:00300031800.014
cellular response to ketoneGO:1901655510.014
regulation of catabolic processGO:00098941130.014
regulation of plasminogen activationGO:001075520.013
telencephalon developmentGO:0021537620.013
cellular macromolecule localizationGO:00707271220.013
response to ethanolGO:00454711620.013
cell part morphogenesisGO:00329901230.013
response to radiationGO:00093141370.013
cellular response to extracellular stimulusGO:0031668730.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
positive regulation of phosphorus metabolic processGO:00105622620.013
catenin import into nucleusGO:003541110.013
dendrite developmentGO:0016358720.013
positive regulation of secretionGO:00510471400.013
cellular macromolecular complex assemblyGO:0034622580.013
negative regulation of protein processingGO:0010955470.013
negative regulation of transportGO:00510511360.013
positive regulation of transferase activityGO:0051347810.013
regulation of neurological system processGO:0031644430.013
positive regulation of kinase activityGO:0033674770.013
feeding behaviorGO:0007631530.013
single organism cellular localizationGO:19025801020.013
positive regulation of blood coagulationGO:003019440.013
regulation of synaptic plasticityGO:0048167700.013
ion homeostasisGO:00508012120.013
regulation of kinase activityGO:00435491170.013
camp biosynthetic processGO:0006171470.013
protein processingGO:0016485680.013
axis specificationGO:000979840.013
regulation of camp metabolic processGO:0030814430.012
response to triglycerideGO:003401430.012
negative regulation of epithelial cell proliferationGO:0050680160.012
cellular response to inorganic substanceGO:0071241650.012
response to vitamin b6GO:003451610.012
axon developmentGO:0061564960.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
Rat
cellular response to hypoxiaGO:0071456510.012
ras protein signal transductionGO:0007265290.012
regulation of protein phosphorylationGO:00019321830.012
male gamete generationGO:0048232990.012
cellular response to monosaccharide stimulusGO:0071326670.012
negative regulation of protein metabolic processGO:00512481140.012
positive regulation of protein modification processGO:00314011420.012
sensory perception of bitter tasteGO:005091340.012
organophosphate metabolic processGO:00196373700.012
cytokine productionGO:0001816610.012
cellular response to alkaloidGO:0071312250.012
positive regulation of protein metabolic processGO:00512471780.012
nuclear transportGO:0051169490.012
purine nucleotide biosynthetic processGO:0006164830.011
response to tumor necrosis factorGO:0034612560.011
regulation of hydrolase activityGO:00513361430.011
ensheathment of neuronsGO:0007272400.011
gamete generationGO:00072761240.011
positive regulation of programmed cell deathGO:00430681570.011
negative regulation of peptidase activityGO:0010466380.011
regulation of transferase activityGO:00513381230.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
cellular response to oxygen levelsGO:0071453600.011
negative regulation of cell communicationGO:00106481580.011
cellular response to metal ionGO:0071248550.011
extracellular matrix organizationGO:0030198130.011
response to estradiolGO:00323551640.011
response to increased oxygen levelsGO:0036296450.011
protein autophosphorylationGO:0046777660.011
organonitrogen compound biosynthetic processGO:19015661670.011
cellular amide metabolic processGO:0043603440.011
cell migrationGO:00164771970.011
regulation of neuron differentiationGO:00456642080.011
sterol catabolic processGO:001612710.011
regulation of cellular component movementGO:00512701500.011
ribose phosphate metabolic processGO:00196932350.011
response to transforming growth factor betaGO:0071559460.011
hormone metabolic processGO:0042445690.011
response to hyperoxiaGO:0055093450.011
response to dexamethasoneGO:0071548490.011
cellular ion homeostasisGO:00068731840.010
positive regulation of behaviorGO:0048520380.010
defense response to gram negative bacteriumGO:005082930.010
regulation of exocytosisGO:0017157370.010
macroautophagyGO:001623640.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.010
adult locomotory behaviorGO:000834440.010
regulation of protein kinase activityGO:00458591050.010
gonad developmentGO:00084061040.010
endocytosisGO:0006897840.010
kidney developmentGO:0001822670.010
purine ribonucleotide metabolic processGO:00091502270.010
chromosome segregationGO:000705920.010
regulation of peptidase activityGO:0052547550.010
positive regulation of calcium ion transportGO:0051928360.010
regulation of immune system processGO:00026821230.010
protein catabolic processGO:0030163300.010

Foxa2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.037
inherited metabolic disorderDOID:65500.037
lower respiratory tract diseaseDOID:005016100.019
respiratory system diseaseDOID:157900.019
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.017