| cellular modified amino acid metabolic process | GO:0006575 | 61 | 0.575 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.560 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.387 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.383 | |
| glutathione metabolic process | GO:0006749 | 15 | 0.273 | |
| sulfur compound metabolic process | GO:0006790 | 70 | 0.126 | |
| carboxylic acid biosynthetic process | GO:0046394 | 83 | 0.113 | |
| organic acid biosynthetic process | GO:0016053 | 83 | 0.108 | |
| cellular catabolic process | GO:0044248 | 295 | 0.100 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.097 | |
| aging | GO:0007568 | 241 | 0.094 | |
| tissue development | GO:0009888 | 252 | 0.088 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.075 | |
| apoptotic process | GO:0006915 | 381 | 0.070 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.067 | |
| cellular amide metabolic process | GO:0043603 | 44 | 0.064 | |
| peptide metabolic process | GO:0006518 | 32 | 0.064 | |
| single organism reproductive process | GO:0044702 | 297 | 0.063 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.062 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.060 | |
| glutathione biosynthetic process | GO:0006750 | 3 | 0.058 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.057 | |
| regulation of molecular function | GO:0065009 | 398 | 0.056 | |
| response to inorganic substance | GO:0010035 | 377 | 0.054 | |
| cellular response to stress | GO:0033554 | 269 | 0.053 | |
| regulation of ion transport | GO:0043269 | 245 | 0.053 | |
| reproductive process | GO:0022414 | 372 | 0.052 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.052 | |
| neuron apoptotic process | GO:0051402 | 88 | 0.051 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.051 | |
| central nervous system development | GO:0007417 | 311 | 0.049 | |
| single organism catabolic process | GO:0044712 | 283 | 0.047 | |
| cofactor metabolic process | GO:0051186 | 95 | 0.047 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.047 | |
| reproduction | GO:0000003 | 245 | 0.047 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.047 | |
| response to wounding | GO:0009611 | 254 | 0.046 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.046 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.046 | |
| programmed cell death | GO:0012501 | 392 | 0.045 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.044 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.044 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.043 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.043 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.042 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.041 | |
| cellular response to external stimulus | GO:0071496 | 118 | 0.041 | |
| ion homeostasis | GO:0050801 | 212 | 0.040 | |
| behavior | GO:0007610 | 205 | 0.040 | |
| cellular modified amino acid biosynthetic process | GO:0042398 | 18 | 0.040 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.038 | |
| monocarboxylic acid metabolic process | GO:0032787 | 152 | 0.038 | |
| cellular homeostasis | GO:0019725 | 252 | 0.036 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.036 | |
| sexual reproduction | GO:0019953 | 148 | 0.036 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.035 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.035 | |
| reactive oxygen species metabolic process | GO:0072593 | 37 | 0.035 | |
| response to radiation | GO:0009314 | 137 | 0.034 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.034 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.034 | |
| homeostatic process | GO:0042592 | 331 | 0.034 | |
| catabolic process | GO:0009056 | 351 | 0.033 | |
| cellular calcium ion homeostasis | GO:0006874 | 160 | 0.033 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.033 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.033 | |
| small molecule catabolic process | GO:0044282 | 59 | 0.033 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.032 | |
| protein phosphorylation | GO:0006468 | 345 | 0.032 | |
| response to toxic substance | GO:0009636 | 133 | 0.032 | |
| response to nutrient | GO:0007584 | 248 | 0.032 | |
| oxidation reduction process | GO:0055114 | 304 | 0.032 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.031 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.030 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.029 | |
| neurological system process | GO:0050877 | 219 | 0.029 | |
| mechanoreceptor differentiation | GO:0042490 | 2 | 0.028 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.028 | |
| single organism organelle organization | GO:1902589 | 180 | 0.028 | |
| neuron death | GO:0070997 | 127 | 0.028 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.028 | |
| cation homeostasis | GO:0055080 | 195 | 0.028 | |
| response to oxidative stress | GO:0006979 | 186 | 0.028 | |
| response to antibiotic | GO:0046677 | 39 | 0.028 | |
| epithelium development | GO:0060429 | 96 | 0.027 | |
| cellular response to reactive oxygen species | GO:0034614 | 55 | 0.027 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.027 | |
| cellular response to organic cyclic compound | GO:0071407 | 202 | 0.027 | |
| response to nutrient levels | GO:0031667 | 370 | 0.026 | |
| fatty acid metabolic process | GO:0006631 | 99 | 0.026 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.026 | |
| peptidyl amino acid modification | GO:0018193 | 126 | 0.026 | |
| organic hydroxy compound metabolic process | GO:1901615 | 115 | 0.026 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.025 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.025 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.025 | |
| brain development | GO:0007420 | 247 | 0.025 | |
| protein oligomerization | GO:0051259 | 191 | 0.025 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.025 | |
| cell type specific apoptotic process | GO:0097285 | 134 | 0.025 | |
| regulation of neuron death | GO:1901214 | 115 | 0.025 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.025 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.024 | |
| cellular response to lipid | GO:0071396 | 201 | 0.024 | |
| response to ethanol | GO:0045471 | 162 | 0.024 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.024 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.024 | |
| transcription dna templated | GO:0006351 | 377 | 0.024 | |
| calcium ion transport | GO:0006816 | 131 | 0.023 | |
| organelle organization | GO:0006996 | 266 | 0.023 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.023 | |
| protein complex assembly | GO:0006461 | 263 | 0.023 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.023 | |
| very long chain fatty acid metabolic process | GO:0000038 | 3 | 0.022 | |
| gamete generation | GO:0007276 | 124 | 0.022 | |
| rna metabolic process | GO:0016070 | 406 | 0.022 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.022 | |
| response to ketone | GO:1901654 | 182 | 0.021 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.021 | |
| spermatogenesis | GO:0007283 | 99 | 0.021 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.021 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.021 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.020 | |
| divalent inorganic cation transport | GO:0072511 | 134 | 0.020 | |
| transmembrane transport | GO:0055085 | 412 | 0.020 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.020 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.020 | |
| head development | GO:0060322 | 247 | 0.020 | |
| chemical homeostasis | GO:0048878 | 292 | 0.019 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.019 | |
| cell cell signaling | GO:0007267 | 335 | 0.019 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.019 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.019 | |
| regulation of calcium ion transport | GO:0051924 | 77 | 0.019 | |
| generation of precursor metabolites and energy | GO:0006091 | 62 | 0.019 | |
| intracellular transport | GO:0046907 | 185 | 0.019 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 140 | 0.019 | |
| cellular component assembly | GO:0022607 | 360 | 0.019 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.018 | |
| cell projection organization | GO:0030030 | 302 | 0.018 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.018 | |
| metal ion transport | GO:0030001 | 289 | 0.018 | |
| response to peptide hormone | GO:0043434 | 278 | 0.017 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.017 | |
| synaptic transmission | GO:0007268 | 235 | 0.017 | |
| defense response | GO:0006952 | 194 | 0.017 | |
| lipid metabolic process | GO:0006629 | 283 | 0.017 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.017 | |
| regulation of response to stress | GO:0080134 | 126 | 0.017 | |
| regulation of anatomical structure size | GO:0090066 | 135 | 0.017 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.017 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.016 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.016 | |
| neuron differentiation | GO:0030182 | 368 | 0.016 | |
| single organism behavior | GO:0044708 | 130 | 0.016 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.016 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.016 | |
| cell morphogenesis | GO:0000902 | 142 | 0.016 | |
| nicotinamide nucleotide metabolic process | GO:0046496 | 28 | 0.015 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.015 | |
| regulation of metal ion transport | GO:0010959 | 118 | 0.015 | |
| regulation of system process | GO:0044057 | 208 | 0.015 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.015 | |
| male gamete generation | GO:0048232 | 99 | 0.015 | |
| response to corticosteroid | GO:0031960 | 235 | 0.015 | |
| muscle contraction | GO:0006936 | 88 | 0.015 | |
| neuronal action potential | GO:0019228 | 35 | 0.015 | |
| urogenital system development | GO:0001655 | 78 | 0.015 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.015 | |
| negative regulation of innate immune response | GO:0045824 | 4 | 0.014 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.014 | |
| muscle system process | GO:0003012 | 115 | 0.014 | |
| axon development | GO:0061564 | 96 | 0.014 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.014 | |
| response to acid chemical | GO:0001101 | 222 | 0.014 | |
| cellular response to nutrient levels | GO:0031669 | 60 | 0.014 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.014 | |
| cellular cation homeostasis | GO:0030003 | 180 | 0.014 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.014 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.014 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.014 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.014 | |
| sex differentiation | GO:0007548 | 113 | 0.014 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.014 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.014 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.014 | |
| divalent inorganic cation homeostasis | GO:0072507 | 165 | 0.014 | |
| amine metabolic process | GO:0009308 | 38 | 0.014 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.013 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 2 | 0.013 | |
| reproductive structure development | GO:0048608 | 128 | 0.013 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.013 | |
| positive regulation of neurogenesis | GO:0050769 | 165 | 0.013 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.013 | |
| hormone metabolic process | GO:0042445 | 69 | 0.013 | |
| aromatic amino acid family catabolic process | GO:0009074 | 7 | 0.013 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.013 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.013 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.013 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.013 | |
| cellular component morphogenesis | GO:0032989 | 155 | 0.013 | |
| response to estrogen | GO:0043627 | 232 | 0.013 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.013 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.012 | |
| response to peptide | GO:1901652 | 292 | 0.012 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.012 | |
| signal transduction by phosphorylation | GO:0023014 | 144 | 0.012 | |
| regulation of intracellular transport | GO:0032386 | 65 | 0.012 | |
| calcium ion homeostasis | GO:0055074 | 162 | 0.012 | |
| cellular carbohydrate metabolic process | GO:0044262 | 72 | 0.012 | |
| axis specification | GO:0009798 | 4 | 0.012 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.012 | |
| positive regulation of transporter activity | GO:0032411 | 14 | 0.012 | |
| organic anion transport | GO:0015711 | 132 | 0.012 | |
| negative regulation of neurogenesis | GO:0050768 | 78 | 0.012 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.012 | |
| positive regulation of transport | GO:0051050 | 245 | 0.012 | |
| regulation of cell projection organization | GO:0031344 | 175 | 0.012 | |
| positive regulation of kinase activity | GO:0033674 | 77 | 0.012 | |
| regulation of cell development | GO:0060284 | 263 | 0.012 | |
| inflammatory response | GO:0006954 | 150 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.011 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.011 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.011 | |
| regulation of nucleotide metabolic process | GO:0006140 | 117 | 0.011 | |
| multicellular organismal homeostasis | GO:0048871 | 49 | 0.011 | |
| lipid biosynthetic process | GO:0008610 | 128 | 0.011 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.011 | |
| negative regulation of neuron death | GO:1901215 | 69 | 0.011 | |
| locomotion | GO:0040011 | 237 | 0.011 | |
| circulatory system process | GO:0003013 | 183 | 0.011 | |
| response to hexose | GO:0009746 | 144 | 0.011 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.011 | |
| neuron development | GO:0048666 | 286 | 0.011 | |
| epithelial cell differentiation | GO:0030855 | 71 | 0.011 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.011 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.011 | |
| negative regulation of transport | GO:0051051 | 136 | 0.011 | |
| gliogenesis | GO:0042063 | 93 | 0.011 | |
| sequestering of metal ion | GO:0051238 | 9 | 0.011 | |
| protein homooligomerization | GO:0051260 | 91 | 0.011 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.010 | |
| response to metal ion | GO:0010038 | 253 | 0.010 | |
| macromolecule localization | GO:0033036 | 252 | 0.010 | |
| response to hydrogen peroxide | GO:0042542 | 89 | 0.010 | |
| anterior posterior pattern specification | GO:0009952 | 1 | 0.010 | |
| response to estradiol | GO:0032355 | 164 | 0.010 | |
| tube development | GO:0035295 | 89 | 0.010 | |
| positive regulation of transmembrane transport | GO:0034764 | 25 | 0.010 | |
| transmission of nerve impulse | GO:0019226 | 42 | 0.010 | |
| oxidoreduction coenzyme metabolic process | GO:0006733 | 31 | 0.010 | |
| response to amino acid | GO:0043200 | 75 | 0.010 | |
| blood circulation | GO:0008015 | 183 | 0.010 | |
| coenzyme metabolic process | GO:0006732 | 86 | 0.010 | |