Rattus norvegicus

216 known processes

Timp2

TIMP metallopeptidase inhibitor 2

(Aliases: MGC105282)

Timp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wound healingGO:00420601220.921
Rat
regulation of cell motilityGO:20001451310.626
response to woundingGO:00096112540.605
Rat
regulation of locomotionGO:00400121480.468
regulation of cellular component movementGO:00512701500.423
regulation of cell proliferationGO:00421273590.383
tissue developmentGO:00098882520.372
Rat
regulation of cellular component organizationGO:00511283680.369
regulation of cell migrationGO:00303341280.346
glial cell differentiationGO:0010001650.334
regenerationGO:00310991630.329
Rat
response to cytokineGO:00340972150.323
cell motilityGO:00488702020.314
locomotionGO:00400112370.310
response to corticosteroidGO:00319602350.293
response to extracellular stimulusGO:00099913800.277
Rat
response to metal ionGO:00100382530.274
negative regulation of cell deathGO:00605482290.266
Rat
enzyme linked receptor protein signaling pathwayGO:00071671160.225
response to growth factorGO:00708481890.202
gliogenesisGO:0042063930.197
negative regulation of multicellular organismal processGO:00512412030.194
reproductive processGO:00224143720.192
Rat
vesicle mediated transportGO:00161921810.190
negative regulation of apoptotic processGO:00430661810.190
Rat
response to estradiolGO:00323551640.189
agingGO:00075682410.184
single organism reproductive processGO:00447022970.181
Rat
regulation of programmed cell deathGO:00430673410.180
Rat
response to peptideGO:19016522920.179
Rat
apoptotic processGO:00069153810.178
Rat
urogenital system developmentGO:0001655780.166
regulation of cellular protein metabolic processGO:00322682670.161
response to nutrientGO:00075842480.161
Rat
response to nutrient levelsGO:00316673700.160
Rat
response to glucocorticoidGO:00513842230.158
response to inorganic substanceGO:00100353770.151
cellular response to endogenous stimulusGO:00714953770.147
response to peptide hormoneGO:00434342780.146
Rat
response to estrogenGO:00436272320.144
Rat
regulation of neuron differentiationGO:00456642080.143
cellular response to growth factor stimulusGO:00713631620.139
regulation of multicellular organismal developmentGO:20000263760.138
response to acid chemicalGO:00011012220.134
Rat
central nervous system developmentGO:00074173110.129
localization of cellGO:00516742020.128
positive regulation of multicellular organismal processGO:00512403870.128
neuron developmentGO:00486662860.126
cellular component movementGO:00069282480.125
positive regulation of cell migrationGO:0030335960.123
positive regulation of cell proliferationGO:00082842490.123
regulation of protein metabolic processGO:00512462890.120
cell projection organizationGO:00300303020.116
regulation of cell projection organizationGO:00313441750.111
positive regulation of cell differentiationGO:00455972170.110
negative regulation of response to stimulusGO:00485851550.109
positive regulation of cellular component movementGO:00512721020.107
response to amino acidGO:0043200750.107
Rat
response to reactive oxygen speciesGO:00003021200.105
head developmentGO:00603222470.103
growthGO:00400071650.102
Rat
regulation of cell morphogenesisGO:0022604770.102
biological adhesionGO:00226101100.101
positive regulation of intracellular signal transductionGO:19025331380.101
cellular component assemblyGO:00226073600.095
cellular response to organic cyclic compoundGO:00714072020.094
positive regulation of signalingGO:00230562700.094
regulation of phosphate metabolic processGO:00192203490.092
response to external biotic stimulusGO:00432072210.091
Rat
cardiovascular system developmentGO:00723581340.090
reproductionGO:00000032450.090
Rat
positive regulation of cell projection organizationGO:00313461110.087
response to carbohydrateGO:00097431830.086
macromolecule localizationGO:00330362520.085
regulation of nervous system developmentGO:00519602640.082
cell adhesionGO:00071551100.082
cellular response to oxygen containing compoundGO:19017013860.081
sensory organ developmentGO:0007423740.080
multi multicellular organism processGO:00447061380.078
chemical homeostasisGO:00488782920.077
negative regulation of programmed cell deathGO:00430691830.075
Rat
response to other organismGO:00517072200.075
Rat
multicellular organism reproductionGO:00325042330.074
Rat
positive regulation of nervous system developmentGO:00519621780.073
sulfur compound metabolic processGO:0006790700.070
positive regulation of phosphate metabolic processGO:00459372620.069
positive regulation of cell communicationGO:00106472710.068
reproductive system developmentGO:00614581280.066
peptide metabolic processGO:0006518320.065
response to interleukin 1GO:0070555550.065
regulation of viral transcriptionGO:004678220.065
glial cell developmentGO:0021782190.065
regulation of growthGO:00400081050.065
cellular response to hormone stimulusGO:00328702470.064
negative regulation of peptidase activityGO:0010466380.062
negative regulation of cell developmentGO:0010721820.060
positive regulation of cell motilityGO:2000147970.059
regulation of schwann cell migrationGO:190014720.057
regulation of epithelial cell proliferationGO:0050678490.056
developmental growthGO:00485891000.056
Rat
neuron projection developmentGO:00311752730.056
carboxylic acid metabolic processGO:00197522890.055
secretionGO:00469033070.054
organic acid metabolic processGO:00060822920.053
protein complex biogenesisGO:00702712630.053
negative regulation of cellular component organizationGO:0051129830.052
cellular component biogenesisGO:00440853680.051
secretion by cellGO:00329402480.051
regulation of axonogenesisGO:0050770370.050
cellular homeostasisGO:00197252520.048
positive regulation of neuron projection developmentGO:0010976990.048
response to axon injuryGO:0048678590.048
positive regulation of locomotionGO:00400171020.045
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.045
negative regulation of hemostasisGO:190004760.045
cellular response to metal ionGO:0071248550.044
negative regulation of developmental processGO:00510931250.044
oxoacid metabolic processGO:00434362900.044
multi organism reproductive processGO:00447032620.043
cellular amino acid metabolic processGO:00065201070.042
single organism biosynthetic processGO:00447113420.042
protein complex assemblyGO:00064612630.041
macromolecular complex assemblyGO:00650032730.041
regulation of neurogenesisGO:00507672470.041
behaviorGO:00076102050.041
regulation of apoptotic processGO:00429813350.040
Rat
response to campGO:0051591910.040
brain developmentGO:00074202470.039
intracellular signal transductionGO:00355563140.039
positive regulation of response to stimulusGO:00485842850.039
response to ethanolGO:00454711620.039
carbohydrate derivative metabolic processGO:19011353460.039
negative regulation of phosphate metabolic processGO:0045936800.038
response to bacteriumGO:00096172000.038
Rat
regulation of cell differentiationGO:00455953200.037
skeletal system developmentGO:0001501410.036
Rat
homeostatic processGO:00425923310.036
morphogenesis of an epitheliumGO:0002009200.036
cell migrationGO:00164771970.036
regulation of response to stressGO:00801341260.036
extracellular matrix organizationGO:0030198130.036
protein homooligomerizationGO:0051260910.036
response to cadmium ionGO:0046686350.035
regulation of catalytic activityGO:00507903040.035
regulation of hydrolase activityGO:00513361430.035
cellular response to corticosteroid stimulusGO:0071384690.035
respiratory system developmentGO:0060541450.034
cell type specific apoptotic processGO:00972851340.034
monovalent inorganic cation transportGO:00156721720.034
multicellular organismal catabolic processGO:004424320.034
axonogenesisGO:0007409710.034
response to retinoic acidGO:0032526630.034
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.034
regulation of cell growthGO:0001558850.033
metal ion transportGO:00300012890.033
female pregnancyGO:00075651220.033
positive regulation of gene expressionGO:00106282440.033
astrocyte developmentGO:001400240.033
cellular response to cytokine stimulusGO:00713451270.033
multicellular organismal macromolecule metabolic processGO:0044259210.032
epithelial cell differentiationGO:0030855710.032
negative regulation of neurogenesisGO:0050768780.032
positive regulation of developmental processGO:00510942830.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
regulation of response to woundingGO:1903034690.031
endocrine system developmentGO:0035270300.031
regulation of cell adhesionGO:0030155520.030
protein phosphorylationGO:00064683450.030
connective tissue developmentGO:0061448330.030
Rat
positive regulation of cellular component organizationGO:00511302000.029
positive regulation of neurogenesisGO:00507691650.028
divalent inorganic cation transportGO:00725111340.028
regulation of neuron projection developmentGO:00109751610.028
cell growthGO:00160491040.028
regulation of homotypic cell cell adhesionGO:003411040.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.027
reproductive structure developmentGO:00486081280.027
tube developmentGO:0035295890.027
sexual reproductionGO:00199531480.027
response to vitaminGO:00332731310.027
Rat
response to radiationGO:00093141370.027
programmed cell deathGO:00125013920.027
Rat
protein complex subunit organizationGO:00718223020.027
response to mechanical stimulusGO:00096121340.026
Rat
cell morphogenesis involved in differentiationGO:00009041190.026
intracellular transportGO:00469071850.026
positive regulation of neuron differentiationGO:00456661260.026
respiratory tube developmentGO:0030323430.026
gland developmentGO:00487321550.026
rna biosynthetic processGO:00327743800.026
regulation of response to external stimulusGO:00321011060.026
inorganic cation transmembrane transportGO:00986622020.025
cellular ketone metabolic processGO:0042180510.025
negative regulation of response to external stimulusGO:0032102370.025
negative regulation of response to woundingGO:1903035230.025
multicellular organismal reproductive processGO:00486092330.025
Rat
extracellular structure organizationGO:0043062130.025
cell cell signalingGO:00072673350.025
regulation of intracellular signal transductionGO:19025312180.025
regulation of hormone levelsGO:00108171870.024
developmental process involved in reproductionGO:00030061590.024
positive regulation of dna metabolic processGO:0051054390.024
positive regulation of signal transductionGO:00099671750.024
epithelium developmentGO:0060429960.024
negative regulation of cell differentiationGO:0045596990.024
positive regulation of phosphorus metabolic processGO:00105622620.024
anatomical structure morphogenesisGO:00096532980.024
response to organophosphorusGO:00466831020.023
hormone transportGO:00099141210.023
positive regulation of cell developmentGO:00107201760.023
cellular response to reactive oxygen speciesGO:0034614550.023
gamete generationGO:00072761240.023
regulation of axon extensionGO:0030516240.023
response to glucoseGO:00097491360.023
negative regulation of neuron differentiationGO:0045665620.023
positive regulation of apoptotic processGO:00430651540.023
protein localizationGO:00081041910.023
negative regulation of cellular metabolic processGO:00313242810.023
positive regulation of protein metabolic processGO:00512471780.023
response to ketoneGO:19016541820.022
extracellular fibril organizationGO:004320610.022
ion transmembrane transportGO:00342203650.022
protein oligomerizationGO:00512591910.022
regulation of apoptotic signaling pathwayGO:2001233130.022
multicellular organism growthGO:003526410.022
negative regulation of signalingGO:00230571570.022
protein maturationGO:0051604680.022
response to hexoseGO:00097461440.021
regulation of immune system processGO:00026821230.021
regulation of ion transportGO:00432692450.021
negative regulation of immune responseGO:0050777150.021
cell substrate adhesionGO:0031589290.021
response to fibroblast growth factorGO:0071774290.021
negative regulation of cell projection organizationGO:0031345500.021
macromolecular complex subunit organizationGO:00439333390.021
cellular response to lipidGO:00713962010.021
cellular amide metabolic processGO:0043603440.021
cation transmembrane transportGO:00986552630.021
neuron projection extensionGO:1990138260.020
regulation of epithelial to mesenchymal transitionGO:001071720.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
negative regulation of macromolecule metabolic processGO:00106052600.020
tissue regenerationGO:0042246360.020
Rat
circulatory system developmentGO:00723591340.020
regulation of peptidase activityGO:0052547550.020
coagulationGO:0050817280.020
organ morphogenesisGO:0009887750.020
cation transportGO:00068123820.020
organelle organizationGO:00069962660.020
epithelial cell proliferationGO:0050673540.020
neurological system processGO:00508772190.020
cellular response to steroid hormone stimulusGO:0071383930.020
receptor internalizationGO:0031623140.020
regulation of secretion by cellGO:19035302080.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
divalent inorganic cation homeostasisGO:00725071650.019
regulation of cell morphogenesis involved in differentiationGO:0010769720.019
cellular component morphogenesisGO:00329891550.019
negative regulation of neuron apoptotic processGO:0043524450.019
cellular amine metabolic processGO:0044106380.019
response to hydrogen peroxideGO:0042542890.019
cellular response to inorganic substanceGO:0071241650.019
cellular protein localizationGO:00346131220.019
regulation of phosphorus metabolic processGO:00511743490.019
single organism intracellular transportGO:19025821660.019
positive regulation of cell deathGO:00109421840.019
regulation of cellular ketone metabolic processGO:0010565270.018
kidney developmentGO:0001822670.018
axon extensionGO:0048675260.018
apoptotic signaling pathwayGO:0097190270.018
blood coagulationGO:0007596260.018
negative regulation of proteolysisGO:0045861410.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
regulation of cellular amine metabolic processGO:003323880.017
response to purine containing compoundGO:00140741260.017
regulation of lipid metabolic processGO:0019216680.017
positive regulation of endothelial cell migrationGO:001059540.017
cytoplasmic transportGO:00164821150.017
response to transition metal nanoparticleGO:19902671220.017
cellular response to glucocorticoid stimulusGO:0071385680.017
negative regulation of gene expressionGO:00106291990.017
nucleobase containing small molecule metabolic processGO:00550863160.017
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.017
cell activationGO:0001775970.016
Rat
tissue morphogenesisGO:0048729220.016
regulation of cell developmentGO:00602842630.016
neuron differentiationGO:00301823680.016
regulation of protein phosphorylationGO:00019321830.016
response to folic acidGO:0051593140.016
Rat
cellular response to external stimulusGO:00714961180.016
immune system processGO:00023762040.016
positive regulation of protein modification processGO:00314011420.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of protein phosphorylationGO:00019341350.016
positive regulation of cellular biosynthetic processGO:00313282950.016
muscle cell apoptotic processGO:0010657300.016
developmental growth involved in morphogenesisGO:0060560330.016
endocytosisGO:0006897840.016
reactive oxygen species metabolic processGO:0072593370.016
synaptic transmissionGO:00072682350.015
neuron deathGO:00709971270.015
response to monosaccharideGO:00342841590.015
cell part morphogenesisGO:00329901230.015
regulation of anatomical structure morphogenesisGO:00226031410.015
positive regulation of cell growthGO:0030307440.015
regulation of nucleic acid templated transcriptionGO:19035063800.015
negative regulation of wound healingGO:006104580.015
cellular response to fibroblast growth factor stimulusGO:0044344240.015
negative regulation of cell proliferationGO:00082851190.015
regulation of molecular functionGO:00650093980.015
positive regulation of transportGO:00510502450.015
ribose phosphate metabolic processGO:00196932350.015
transcription from rna polymerase ii promoterGO:00063662520.015
cellular macromolecular complex assemblyGO:0034622580.015
regulation of cellular amino acid metabolic processGO:000652120.015
regulation of phosphorylationGO:00423252480.015
lung developmentGO:0030324430.015
steroid metabolic processGO:0008202730.015
signal transduction by phosphorylationGO:00230141440.015
response to corticosteroneGO:0051412400.014
negative regulation of endopeptidase activityGO:0010951360.014
cation homeostasisGO:00550801950.014
regulation of body fluid levelsGO:0050878900.014
calcium ion transportGO:00068161310.014
cellular catabolic processGO:00442482950.014
striated muscle tissue developmentGO:0014706580.014
response to insulinGO:00328681330.014
bone developmentGO:0060348250.014
positive regulation of cellular protein metabolic processGO:00322701670.014
negative regulation of molecular functionGO:00440921330.014
negative regulation of protein processingGO:0010955470.014
receptor metabolic processGO:0043112180.014
muscle tissue developmentGO:0060537580.014
negative regulation of neuron projection developmentGO:0010977460.014
cellular response to transforming growth factor beta stimulusGO:0071560410.013
response to molecule of bacterial originGO:00022371940.013
Rat
organonitrogen compound catabolic processGO:19015651790.013
erk1 and erk2 cascadeGO:0070371480.013
response to hypoxiaGO:00016662310.013
rhythmic processGO:00485111560.013
Rat
actin cytoskeleton organizationGO:0030036730.013
single organism cell adhesionGO:0098602460.013
response to oxygen levelsGO:00704822650.013
mapk cascadeGO:00001651400.013
male gamete generationGO:0048232990.013
regulation of secretionGO:00510462240.013
establishment of vesicle localizationGO:0051650310.013
cortical actin cytoskeleton organizationGO:003086620.013
regulation of bmp signaling pathwayGO:003051020.013
negative regulation of neuron deathGO:1901215690.013
cranial suture morphogenesisGO:006036340.013
single organismal cell cell adhesionGO:0016337420.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cellular response to abiotic stimulusGO:0071214850.012
regulation of cellular component sizeGO:0032535510.012
dna metabolic processGO:0006259960.012
positive regulation of catalytic activityGO:00430851840.012
cellular potassium ion transportGO:0071804720.012
regulation of erythrocyte aggregationGO:003411810.012
regulation of system processGO:00440572080.012
regulation of nucleocytoplasmic transportGO:0046822280.012
membrane fusionGO:0061025260.012
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.012
amide transportGO:00428861050.012
cell morphogenesisGO:00009021420.012
peptidyl amino acid modificationGO:00181931260.012
response to ionizing radiationGO:0010212590.012
positive regulation of axon extensionGO:0045773140.011
hormone metabolic processGO:0042445690.011
regulation of rna biosynthetic processGO:20011413810.011
regulation of extrinsic apoptotic signaling pathwayGO:200123670.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
regulation of wound healingGO:0061041140.011
response to decreased oxygen levelsGO:00362932370.011
lipid localizationGO:0010876620.011
response to vitamin dGO:0033280340.011
regulation of embryonic developmentGO:004599520.011
regulation of epithelial cell migrationGO:0010632170.011
response to lead ionGO:0010288330.011
negative regulation of immune system processGO:0002683390.011
collagen fibril organizationGO:003019910.011
response to alkaloidGO:00432791320.011
receptor mediated endocytosisGO:0006898420.011
regulation of fatty acid metabolic processGO:0019217180.011
cell recognitionGO:0008037110.011
cellular response to peptide hormone stimulusGO:00713751200.011
regulation of protein kinase activityGO:00458591050.011
regulation of protein localizationGO:0032880810.011
positive regulation of growthGO:0045927550.011
development of primary sexual characteristicsGO:00451371070.011
neuronal action potentialGO:0019228350.010
regulation of anatomical structure sizeGO:00900661350.010
negative regulation of rna biosynthetic processGO:19026791180.010
telencephalon developmentGO:0021537620.010
amine metabolic processGO:0009308380.010
positive regulation of lipid metabolic processGO:0045834330.010
hemostasisGO:0007599260.010
nucleocytoplasmic transportGO:0006913480.010
craniofacial suture morphogenesisGO:009709440.010
forebrain developmentGO:0030900980.010
cellular protein complex assemblyGO:0043623440.010
maternal process involved in female pregnancyGO:0060135380.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
positive regulation of phosphorylationGO:00423271770.010

Timp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.053
disease of anatomical entityDOID:700.053
musculoskeletal system diseaseDOID:1700.053
nervous system diseaseDOID:86300.037
eye diseaseDOID:561400.025
eye and adnexa diseaseDOID:149200.025
retinal degenerationDOID:846600.025
retinal diseaseDOID:567900.025
sensory system diseaseDOID:005015500.025
bone diseaseDOID:008000100.015
bone development diseaseDOID:008000600.015
osteogenesis imperfectaDOID:1234700.011
osteochondrodysplasiaDOID:225600.011