Rattus norvegicus

15 known processes

Txnrd2

thioredoxin reductase 2

(Aliases: MGC93435,Tr3,Trxr2,Trxrd2)

Txnrd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.275
Rat
oxoacid metabolic processGO:00434362900.250
Rat
carboxylic acid metabolic processGO:00197522890.121
Rat
regulation of rna biosynthetic processGO:20011413810.100
protein phosphorylationGO:00064683450.093
cellular ketone metabolic processGO:0042180510.088
lipid metabolic processGO:00066292830.086
macromolecule localizationGO:00330362520.083
single organism catabolic processGO:00447122830.083
Rat
regulation of molecular functionGO:00650093980.082
intracellular signal transductionGO:00355563140.079
protein localizationGO:00081041910.072
cellular catabolic processGO:00442482950.068
Rat
regulation of signal transductionGO:00099663180.063
regulation of protein phosphorylationGO:00019321830.063
positive regulation of nucleobase containing compound metabolic processGO:00459353190.061
rna biosynthetic processGO:00327743800.060
regulation of nucleic acid templated transcriptionGO:19035063800.060
programmed cell deathGO:00125013920.060
regulation of protein metabolic processGO:00512462890.059
cellular lipid metabolic processGO:00442552080.059
regulation of apoptotic processGO:00429813350.058
protein complex assemblyGO:00064612630.058
Rat
regulation of phosphorus metabolic processGO:00511743490.057
catabolic processGO:00090563510.056
Rat
organic hydroxy compound metabolic processGO:19016151150.055
positive regulation of nitrogen compound metabolic processGO:00511733340.055
negative regulation of metabolic processGO:00098923310.053
organic substance catabolic processGO:19015753160.053
regulation of intracellular signal transductionGO:19025312180.053
response to nutrient levelsGO:00316673700.053
positive regulation of transcription dna templatedGO:00458931970.052
carbohydrate derivative metabolic processGO:19011353460.052
immune system processGO:00023762040.051
Mouse
rna metabolic processGO:00160704060.051
cellular response to oxygen containing compoundGO:19017013860.051
Rat
nucleobase containing small molecule metabolic processGO:00550863160.050
Rat
cellular amino acid metabolic processGO:00065201070.050
Rat
response to carbohydrateGO:00097431830.050
response to glucocorticoidGO:00513842230.050
apoptotic processGO:00069153810.049
regulation of transcription dna templatedGO:00063553740.048
lipid biosynthetic processGO:00086101280.048
single organism intracellular transportGO:19025821660.047
macromolecular complex subunit organizationGO:00439333390.046
Rat
protein transportGO:00150311320.046
cellular component assemblyGO:00226073600.045
Rat
anatomical structure morphogenesisGO:00096532980.044
fatty acid metabolic processGO:0006631990.044
cellular response to nitrogen compoundGO:19016992100.044
regulation of cellular amine metabolic processGO:003323880.043
positive regulation of macromolecule biosynthetic processGO:00105572470.043
regulation of rna metabolic processGO:00512523910.043
regulation of cellular protein metabolic processGO:00322682670.042
regulation of cellular amino acid metabolic processGO:000652120.042
transcription dna templatedGO:00063513770.041
neuron projection developmentGO:00311752730.041
positive regulation of biosynthetic processGO:00098913190.040
regulation of programmed cell deathGO:00430673410.040
cellular macromolecule localizationGO:00707271220.040
negative regulation of cell deathGO:00605482290.040
transcription from rna polymerase ii promoterGO:00063662520.039
negative regulation of molecular functionGO:00440921330.039
negative regulation of response to stimulusGO:00485851550.038
establishment of protein localizationGO:00451841410.038
cellular response to peptideGO:19016531330.038
intracellular transportGO:00469071850.038
ion transmembrane transportGO:00342203650.037
organelle organizationGO:00069962660.037
regulation of cellular ketone metabolic processGO:0010565270.036
protein complex biogenesisGO:00702712630.036
Rat
intracellular protein transportGO:0006886790.035
single organism biosynthetic processGO:00447113420.035
regulation of cellular component organizationGO:00511283680.035
negative regulation of cell communicationGO:00106481580.035
regulation of cellular localizationGO:00603412630.035
cellular amine metabolic processGO:0044106380.035
negative regulation of macromolecule metabolic processGO:00106052600.035
peptidyl serine modificationGO:0018209340.035
response to cytokineGO:00340972150.035
immune responseGO:00069551040.035
positive regulation of gene expressionGO:00106282440.034
cellular response to stressGO:00335542690.034
Rat
cellular response to hormone stimulusGO:00328702470.034
cation transportGO:00068123820.034
negative regulation of developmental processGO:00510931250.033
cellular response to insulin stimulusGO:0032869810.033
nucleic acid templated transcriptionGO:00976593790.033
amine metabolic processGO:0009308380.033
cellular component biogenesisGO:00440853680.033
Rat
positive regulation of transportGO:00510502450.033
response to peptideGO:19016522920.033
negative regulation of programmed cell deathGO:00430691830.032
negative regulation of cell differentiationGO:0045596990.032
cell projection organizationGO:00300303020.032
nucleotide metabolic processGO:00091172790.032
Rat
regulation of multicellular organismal developmentGO:20000263760.032
hexose metabolic processGO:0019318580.032
response to peptide hormoneGO:00434342780.032
protein oligomerizationGO:00512591910.032
Rat
cellular component morphogenesisGO:00329891550.032
regulation of phosphate metabolic processGO:00192203490.031
macromolecular complex assemblyGO:00650032730.031
Rat
cellular protein localizationGO:00346131220.031
positive regulation of cellular biosynthetic processGO:00313282950.031
regulation of protein modification processGO:00313991940.031
transmembrane transportGO:00550854120.030
response to monosaccharideGO:00342841590.030
response to insulinGO:00328681330.030
carboxylic acid catabolic processGO:0046395490.030
inorganic ion transmembrane transportGO:00986602290.030
nucleoside phosphate metabolic processGO:00067532830.030
Rat
gland developmentGO:00487321550.029
response to oxidative stressGO:00069791860.029
Rat
positive regulation of rna biosynthetic processGO:19026801970.029
negative regulation of gene expressionGO:00106291990.029
secretionGO:00469033070.029
protein homooligomerizationGO:0051260910.029
negative regulation of cellular metabolic processGO:00313242810.028
positive regulation of molecular functionGO:00440932300.028
negative regulation of cellular biosynthetic processGO:00313271610.028
response to acid chemicalGO:00011012220.028
multi organism reproductive processGO:00447032620.027
cellular response to cytokine stimulusGO:00713451270.027
single organism cellular localizationGO:19025801020.027
carboxylic acid biosynthetic processGO:0046394830.027
negative regulation of multicellular organismal processGO:00512412030.026
organophosphate metabolic processGO:00196373700.026
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.026
negative regulation of signalingGO:00230571570.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.026
regulation of catalytic activityGO:00507903040.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
cellular modified amino acid metabolic processGO:0006575610.026
Rat
reproductionGO:00000032450.025
oxidation reduction processGO:00551143040.025
positive regulation of cellular amine metabolic processGO:003324030.025
response to estrogenGO:00436272320.025
regulation of cell projection organizationGO:00313441750.025
negative regulation of apoptotic processGO:00430661810.025
metal ion transportGO:00300012890.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
regulation of telomerase activityGO:005197220.025
positive regulation of cellular component organizationGO:00511302000.025
cellular homeostasisGO:00197252520.024
cytoplasmic transportGO:00164821150.024
regulation of establishment of protein localizationGO:0070201690.024
purine containing compound metabolic processGO:00725212530.024
single organism reproductive processGO:00447022970.024
Rat
negative regulation of phosphorus metabolic processGO:0010563800.024
axis specificationGO:000979840.024
multicellular organism reproductionGO:00325042330.024
reproductive processGO:00224143720.024
Rat
central nervous system developmentGO:00074173110.024
negative regulation of nucleic acid templated transcriptionGO:19035071170.024
positive regulation of transcription factor import into nucleusGO:004299340.024
peptidyl amino acid modificationGO:00181931260.024
cell morphogenesisGO:00009021420.023
organonitrogen compound biosynthetic processGO:19015661670.023
neuron projection morphogenesisGO:00488121220.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
gastrulationGO:000736920.023
cell part morphogenesisGO:00329901230.023
chemical homeostasisGO:00488782920.023
regulation of nervous system developmentGO:00519602640.023
positive regulation of signal transductionGO:00099671750.023
response to dexamethasoneGO:0071548490.023
regulation of cell developmentGO:00602842630.023
negative regulation of cellular component organizationGO:0051129830.023
response to starvationGO:0042594590.023
response to external biotic stimulusGO:00432072210.022
regulation of cell proliferationGO:00421273590.022
regulation of protein transportGO:0051223680.022
antigen receptor mediated signaling pathwayGO:005085110.022
organic acid biosynthetic processGO:0016053830.022
monovalent inorganic cation transportGO:00156721720.022
regulation of ion transportGO:00432692450.022
organic cyclic compound catabolic processGO:19013611750.022
monocarboxylic acid metabolic processGO:00327871520.022
regulation of protein localizationGO:0032880810.022
cellular response to lipidGO:00713962010.022
response to extracellular stimulusGO:00099913800.022
response to corticosteroidGO:00319602350.022
response to lipopolysaccharideGO:00324961910.022
homeostatic processGO:00425923310.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
positive regulation of neurogenesisGO:00507691650.021
negative regulation of transportGO:00510511360.021
multicellular organismal reproductive processGO:00486092330.021
growthGO:00400071650.021
cell motilityGO:00488702020.021
purine nucleotide metabolic processGO:00061632290.021
negative regulation of rna metabolic processGO:00512531230.021
negative regulation of protein import into nucleus translocationGO:003315910.021
brain developmentGO:00074202470.021
cellular response to organonitrogen compoundGO:00714171970.021
cell growthGO:00160491040.021
embryonic pattern specificationGO:000988010.021
multicellular organism growthGO:003526410.021
negative regulation of signal transductionGO:0009968830.021
tissue developmentGO:00098882520.020
nucleoside metabolic processGO:00091161790.020
positive regulation of developmental processGO:00510942830.020
cellular response to peptide hormone stimulusGO:00713751200.020
carbohydrate metabolic processGO:00059751300.020
positive regulation of rna metabolic processGO:00512542030.020
positive regulation of cell developmentGO:00107201760.020
reproductive structure developmentGO:00486081280.020
Rat
glucose metabolic processGO:0006006520.020
regulation of catabolic processGO:00098941130.020
nucleotide catabolic processGO:00091661390.020
response to metal ionGO:00100382530.020
Rat
response to inorganic substanceGO:00100353770.020
regulation of hormone levelsGO:00108171870.020
regulation of neuron differentiationGO:00456642080.020
protein complex subunit organizationGO:00718223020.020
Rat
single organism membrane organizationGO:0044802740.020
regulation of phosphorylationGO:00423252480.020
negative regulation of biosynthetic processGO:00098901680.019
small gtpase mediated signal transductionGO:0007264360.019
protein targetingGO:0006605610.019
alcohol metabolic processGO:0006066770.019
cellular response to organic cyclic compoundGO:00714072020.019
negative regulation of transcription dna templatedGO:00458921160.019
tube developmentGO:0035295890.019
purine ribonucleotide catabolic processGO:00091541360.019
positive regulation of protein metabolic processGO:00512471780.019
regulation of growthGO:00400081050.019
response to other organismGO:00517072200.019
developmental process involved in reproductionGO:00030061590.019
Rat
neuron developmentGO:00486662860.019
amide transportGO:00428861050.019
positive regulation of cell differentiationGO:00455972170.018
regulation of neurogenesisGO:00507672470.018
neuron differentiationGO:00301823680.018
aromatic compound catabolic processGO:00194391680.018
protein localization to organelleGO:0033365570.018
cell migrationGO:00164771970.018
sexual reproductionGO:00199531480.018
ribose phosphate metabolic processGO:00196932350.018
heart morphogenesisGO:000300730.018
cell projection morphogenesisGO:00488581230.018
regulation of cell differentiationGO:00455953200.018
positive regulation of nervous system developmentGO:00519621780.018
anion transportGO:00068201780.018
anterior posterior pattern specificationGO:000995210.017
organophosphate catabolic processGO:00464341480.017
nucleobase containing compound catabolic processGO:00346551520.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
action potentialGO:0001508540.017
muscle system processGO:00030121150.017
positive regulation of cellular protein metabolic processGO:00322701670.017
response to purine containing compoundGO:00140741260.017
organic acid transportGO:00158491160.017
single organism organelle organizationGO:19025891800.017
head developmentGO:00603222470.017
cell cycleGO:00070491010.017
response to campGO:0051591910.017
negative regulation of protein metabolic processGO:00512481140.017
positive regulation of phosphorus metabolic processGO:00105622620.017
adult locomotory behaviorGO:000834440.017
positive regulation of phosphate metabolic processGO:00459372620.016
positive regulation of cell deathGO:00109421840.016
Rat
thioester metabolic processGO:0035383280.016
inorganic cation transmembrane transportGO:00986622020.016
purine nucleoside metabolic processGO:00422781690.016
acyl coa metabolic processGO:0006637280.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
positive regulation of neuron differentiationGO:00456661260.016
sulfur compound metabolic processGO:0006790700.016
Rat
gamete generationGO:00072761240.016
gonad developmentGO:00084061040.016
peptidyl serine phosphorylationGO:0018105330.016
lymphoid progenitor cell differentiationGO:000232020.016
carboxylic acid transportGO:00469421150.016
defense responseGO:00069521940.016
small molecule biosynthetic processGO:00442831240.016
cation transmembrane transportGO:00986552630.016
positive regulation of phosphorylationGO:00423271770.016
cellular component movementGO:00069282480.016
ribonucleotide metabolic processGO:00092592310.016
urogenital system developmentGO:0001655780.016
regulation of neuron projection developmentGO:00109751610.016
single organism nuclear importGO:1902593350.016
ribonucleoside metabolic processGO:00091191740.016
negative regulation of cell proliferationGO:00082851190.016
nitrogen compound transportGO:00717052290.016
response to organophosphorusGO:00466831020.015
lipid oxidationGO:0034440300.015
nuclear transportGO:0051169490.015
ras protein signal transductionGO:0007265290.015
response to growth factorGO:00708481890.015
regulation of protein kinase activityGO:00458591050.015
regulation of metal ion transportGO:00109591180.015
positive regulation of programmed cell deathGO:00430681570.015
monosaccharide metabolic processGO:0005996610.015
response to bacteriumGO:00096172000.015
organic anion transportGO:00157111320.015
regulation of kinase activityGO:00435491170.015
regulation of transferase activityGO:00513381230.015
transmission of nerve impulseGO:0019226420.015
multi multicellular organism processGO:00447061380.015
regulation of cell growthGO:0001558850.015
reproductive system developmentGO:00614581280.015
Rat
cell morphogenesis involved in differentiationGO:00009041190.015
nucleoside phosphate catabolic processGO:19012921400.015
regulation of membrane potentialGO:00423911100.015
positive regulation of cell communicationGO:00106472710.015
response to nutrientGO:00075842480.014
protein catabolic processGO:0030163300.014
negative regulation of rna biosynthetic processGO:19026791180.014
regulation of lipid metabolic processGO:0019216680.014
hormone transportGO:00099141210.014
glycosyl compound metabolic processGO:19016571820.014
response to decreased oxygen levelsGO:00362932370.014
response to radiationGO:00093141370.014
neuronal action potentialGO:0019228350.014
purine ribonucleotide metabolic processGO:00091502270.014
negative regulation of catalytic activityGO:00430861030.014
neurological system processGO:00508772190.014
vesicle mediated transportGO:00161921810.014
regulation of cell morphogenesisGO:0022604770.014
male sex differentiationGO:0046661640.014
negative regulation of nervous system developmentGO:0051961790.014
regulation of system processGO:00440572080.014
regulation of cellular catabolic processGO:00313291010.014
apoptotic signaling pathwayGO:0097190270.014
response to biotic stimulusGO:00096072260.014
posttranscriptional regulation of gene expressionGO:0010608370.014
chemosensory behaviorGO:000763520.014
protein importGO:0017038370.014
development of primary sexual characteristicsGO:00451371070.014
response to reactive oxygen speciesGO:00003021200.014
Rat
positive regulation of response to stimulusGO:00485842850.013
regulation of immune responseGO:0050776550.013
cell cell signalingGO:00072673350.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
regulation of peptide transportGO:0090087870.013
fatty acid oxidationGO:0019395290.013
cellular chemical homeostasisGO:00550822470.013
heterocycle catabolic processGO:00467001670.013
regulation of transmembrane transporter activityGO:0022898490.013
negative regulation of cell cycle g1 s phase transitionGO:190280720.013
membrane organizationGO:0061024940.013
locomotionGO:00400112370.013
mitochondrion organizationGO:0007005350.013
response to molecule of bacterial originGO:00022371940.013
negative regulation of cellular protein metabolic processGO:00322691060.013
purine ribonucleoside metabolic processGO:00461281680.013
regulation of secretionGO:00510462240.013
short chain fatty acid metabolic processGO:004645930.013
secretion by cellGO:00329402480.013
cellular response to abiotic stimulusGO:0071214850.013
localization of cellGO:00516742020.013
negative regulation of cell developmentGO:0010721820.013
glial cell differentiationGO:0010001650.013
b cell differentiationGO:003018320.013
response to oxygen levelsGO:00704822650.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
regulation of purine nucleotide metabolic processGO:19005421150.013
positive regulation of intracellular signal transductionGO:19025331380.012
lipid storageGO:001991510.012
response to ketoneGO:19016541820.012
metal ion homeostasisGO:00550651860.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
negative regulation of neuron differentiationGO:0045665620.012
regulation of nucleotide metabolic processGO:00061401170.012
regulation of apoptotic signaling pathwayGO:2001233130.012
response to toxic substanceGO:00096361330.012
positive regulation of apoptotic processGO:00430651540.012
actin filament based processGO:0030029860.012
negative regulation of innate immune responseGO:004582440.012
multicellular organismal signalingGO:0035637440.012
cellular response to endogenous stimulusGO:00714953770.012
cellular response to extracellular stimulusGO:0031668730.012
regulation of cellular component biogenesisGO:0044087860.012
fatty acid beta oxidationGO:0006635220.012
response to estradiolGO:00323551640.012
digestive system developmentGO:0055123410.012
response to vitaminGO:00332731310.012
proteolysisGO:00065081750.012
sex differentiationGO:00075481130.012
macromolecule catabolic processGO:0009057580.012
cellular response to growth factor stimulusGO:00713631620.012
nuclear importGO:0051170350.012
positive regulation of catalytic activityGO:00430851840.012
signal releaseGO:00230611450.012
negative regulation of phosphate metabolic processGO:0045936800.012
gliogenesisGO:0042063930.012
lipid localizationGO:0010876620.012
regulation of calcium ion transportGO:0051924770.012
positive regulation of transferase activityGO:0051347810.012
nucleocytoplasmic transportGO:0006913480.012
cellular nitrogen compound catabolic processGO:00442701630.012
negative regulation of cell cycle phase transitionGO:190198840.011
positive regulation of cell proliferationGO:00082842490.011
regulation of neuron deathGO:19012141150.011
peptide transportGO:0015833970.011
cellular response to external stimulusGO:00714961180.011
glycerolipid metabolic processGO:0046486670.011
acetyl coa metabolic processGO:0006084170.011
protein localization to nucleusGO:0034504390.011
anion transmembrane transportGO:0098656770.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.011
response to axon injuryGO:0048678590.011
Rat
regulation of locomotionGO:00400121480.011
regulation of organelle organizationGO:0033043800.011
maintenance of locationGO:0051235170.011
embryonic axis specificationGO:000057810.011
endocrine system developmentGO:0035270300.011
fatty acid biosynthetic processGO:0006633330.011
nucleoside catabolic processGO:00091641260.011
protein tetramerizationGO:0051262380.011
Rat
negative regulation of secretionGO:0051048820.011
regulation of cell cycleGO:0051726730.011
regulation of hydrolase activityGO:00513361430.011
positive regulation of multicellular organismal processGO:00512403870.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
olfactory behaviorGO:004204820.011
steroid metabolic processGO:0008202730.011
ensheathment of neuronsGO:0007272400.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
response to hypoxiaGO:00016662310.011
regulation of intracellular transportGO:0032386650.011
regulation of hormone secretionGO:00468831060.011
purine nucleotide catabolic processGO:00061951360.011
kidney developmentGO:0001822670.011
cation homeostasisGO:00550801950.011
olfactory learningGO:000835510.011
spindle organizationGO:000705120.011
protein targeting to nucleusGO:0044744350.011
guanosine containing compound catabolic processGO:1901069710.010
glycosyl compound catabolic processGO:19016581260.010
programmed necrotic cell deathGO:009730020.010
female pregnancyGO:00075651220.010
negative regulation of protein phosphorylationGO:0001933440.010
response to retinoic acidGO:0032526630.010
vitamin d3 metabolic processGO:007064020.010
icosanoid biosynthetic processGO:0046456180.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
positive regulation of mitochondrion organizationGO:001082240.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
carbohydrate derivative biosynthetic processGO:19011371240.010
calcium mediated signaling using intracellular calcium sourceGO:003558410.010
purine ribonucleoside catabolic processGO:00461301240.010
cardiac chamber developmentGO:000320510.010
response to ethanolGO:00454711620.010
response to ionizing radiationGO:0010212590.010

Txnrd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.012
carbohydrate metabolic disorderDOID:297800.011
central nervous system diseaseDOID:33100.011