Rattus norvegicus

122 known processes

Txnrd1

thioredoxin reductase 1

(Aliases: MGC93353,Tr)

Txnrd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic processGO:00069153810.560
programmed cell deathGO:00125013920.479
regulation of programmed cell deathGO:00430673410.407
cellular amino acid metabolic processGO:00065201070.341
cellular response to external stimulusGO:00714961180.299
response to nitrosative stressGO:005140920.293
negative regulation of cell deathGO:00605482290.276
cellular modified amino acid biosynthetic processGO:0042398180.243
chromosome segregationGO:000705920.206
negative regulation of apoptotic processGO:00430661810.205
cellular amino acid biosynthetic processGO:0008652320.204
intracellular signal transductionGO:00355563140.195
response to oxidative stressGO:00069791860.190
positive regulation of biosynthetic processGO:00098913190.182
positive regulation of cellular biosynthetic processGO:00313282950.163
regulation of catalytic activityGO:00507903040.158
mitotic spindle organizationGO:000705220.158
carbohydrate metabolic processGO:00059751300.149
cellular response to alkaloidGO:0071312250.148
negative regulation of programmed cell deathGO:00430691830.146
organelle organizationGO:00069962660.144
organic acid metabolic processGO:00060822920.138
cellular response to stressGO:00335542690.131
positive regulation of multicellular organismal processGO:00512403870.128
spindle organizationGO:000705120.126
peptide biosynthetic processGO:004304330.126
response to oxygen levelsGO:00704822650.124
positive regulation of gene expressionGO:00106282440.115
regulation of apoptotic processGO:00429813350.113
macromolecule localizationGO:00330362520.109
carboxylic acid metabolic processGO:00197522890.107
dna metabolic processGO:0006259960.107
modification dependent macromolecule catabolic processGO:0043632140.102
peptidyl amino acid modificationGO:00181931260.102
regulation of neuron apoptotic processGO:0043523830.100
response to extracellular stimulusGO:00099913800.099
cell type specific apoptotic processGO:00972851340.096
protein complex biogenesisGO:00702712630.095
regulation of ion transportGO:00432692450.094
protein complex assemblyGO:00064612630.091
regulation of molecular functionGO:00650093980.090
regulation of neuron deathGO:19012141150.090
protein complex subunit organizationGO:00718223020.088
protein ubiquitinationGO:0016567280.087
regulation of cellular protein metabolic processGO:00322682670.086
positive regulation of response to stimulusGO:00485842850.086
response to nutrient levelsGO:00316673700.085
positive regulation of rna metabolic processGO:00512542030.083
protein targeting to nucleusGO:0044744350.081
growthGO:00400071650.080
catabolic processGO:00090563510.080
nucleic acid templated transcriptionGO:00976593790.080
response to decreased oxygen levelsGO:00362932370.079
negative regulation of neuron apoptotic processGO:0043524450.076
response to nutrientGO:00075842480.076
cellular response to oxidative stressGO:0034599760.073
sulfur compound biosynthetic processGO:0044272190.071
single organism carbohydrate metabolic processGO:00447231180.071
protein localizationGO:00081041910.069
dendrite developmentGO:0016358720.068
regulation of cellular response to stressGO:0080135490.067
neuron deathGO:00709971270.066
regulation of transcription dna templatedGO:00063553740.066
nuclear transportGO:0051169490.066
regulation of response to stressGO:00801341260.065
rna biosynthetic processGO:00327743800.063
single organism reproductive processGO:00447022970.062
cellular response to nitrogen compoundGO:19016992100.062
macromolecular complex assemblyGO:00650032730.062
apoptotic signaling pathwayGO:0097190270.062
regulation of phosphorus metabolic processGO:00511743490.060
positive regulation of nucleic acid templated transcriptionGO:19035081970.060
signal transduction by phosphorylationGO:00230141440.059
positive regulation of cell communicationGO:00106472710.059
response to ammonium ionGO:0060359710.058
brain developmentGO:00074202470.058
protein phosphorylationGO:00064683450.057
single organism intracellular transportGO:19025821660.055
reproductive processGO:00224143720.054
response to radiationGO:00093141370.052
positive regulation of cellular component biogenesisGO:0044089550.052
small molecule biosynthetic processGO:00442831240.052
negative regulation of muscle cell apoptotic processGO:0010656210.051
agingGO:00075682410.048
meiotic cell cycle processGO:190304630.048
amide biosynthetic processGO:0043604100.047
regulation of phosphate metabolic processGO:00192203490.047
cellular response to endogenous stimulusGO:00714953770.047
cellular modified amino acid metabolic processGO:0006575610.046
positive regulation of nitrogen compound metabolic processGO:00511733340.046
glutathione biosynthetic processGO:000675030.046
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.046
regulation of protein phosphorylationGO:00019321830.045
ncrna metabolic processGO:003466080.045
macromolecular complex subunit organizationGO:00439333390.044
regulation of intracellular signal transductionGO:19025312180.044
single organism organelle organizationGO:19025891800.044
cellular amide metabolic processGO:0043603440.043
cellular protein localizationGO:00346131220.043
immune effector processGO:0002252530.042
cellular chemical homeostasisGO:00550822470.041
oxoacid metabolic processGO:00434362900.041
response to alkaloidGO:00432791320.041
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.041
positive regulation of macromolecule biosynthetic processGO:00105572470.040
multi organism reproductive processGO:00447032620.040
multicellular organism growthGO:003526410.039
regulation of protein metabolic processGO:00512462890.039
regulation of organelle organizationGO:0033043800.039
modification dependent protein catabolic processGO:0019941140.039
meiosis iGO:000712720.039
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729610.038
anatomical structure morphogenesisGO:00096532980.038
Mouse
homeostatic processGO:00425923310.038
positive regulation of phosphorylationGO:00423271770.038
carbohydrate derivative biosynthetic processGO:19011371240.038
single organism cellular localizationGO:19025801020.037
regulation of cellular component biogenesisGO:0044087860.037
regulation of rna metabolic processGO:00512523910.037
peptidyl tyrosine modificationGO:0018212720.037
activation of cysteine type endopeptidase activityGO:009720240.037
regulation of protein modification processGO:00313991940.037
proteolysisGO:00065081750.037
circulatory system processGO:00030131830.036
myeloid cell activation involved in immune responseGO:0002275130.036
actin filament depolymerizationGO:003004230.036
cellular catabolic processGO:00442482950.036
nucleoside monophosphate metabolic processGO:0009123930.035
multicellular organism reproductionGO:00325042330.035
intracellular transportGO:00469071850.035
regulation of cellular component organizationGO:00511283680.034
neuron apoptotic processGO:0051402880.034
positive regulation of developmental processGO:00510942830.034
circulatory system developmentGO:00723591340.034
purine nucleoside monophosphate metabolic processGO:0009126840.033
reactive oxygen species metabolic processGO:0072593370.033
transcription dna templatedGO:00063513770.033
response to hypoxiaGO:00016662310.033
sexual reproductionGO:00199531480.032
negative regulation of developmental processGO:00510931250.032
negative regulation of actin filament depolymerizationGO:003083520.032
jak stat cascadeGO:0007259260.032
organic substance catabolic processGO:19015753160.032
cellular response to nutrient levelsGO:0031669600.031
cellular response to extracellular stimulusGO:0031668730.031
amine metabolic processGO:0009308380.030
autophagic cell deathGO:004810240.030
smooth muscle cell proliferationGO:0048659770.030
regulation of cell proliferationGO:00421273590.030
cellular cation homeostasisGO:00300031800.030
multicellular organismal reproductive processGO:00486092330.030
regulation of cellular localizationGO:00603412630.030
negative regulation of multicellular organismal processGO:00512412030.030
cellular protein complex assemblyGO:0043623440.030
maintenance of locationGO:0051235170.029
ncrna processingGO:003447030.029
positive regulation of rna biosynthetic processGO:19026801970.029
positive regulation of organelle organizationGO:0010638480.029
head developmentGO:00603222470.029
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.029
cytoskeleton organizationGO:00070101110.028
muscle cell proliferationGO:0033002840.028
nonribosomal peptide biosynthetic processGO:001918430.028
regulation of response to tumor cellGO:000283430.028
cellular metal ion homeostasisGO:00068751720.028
defense responseGO:00069521940.028
regulation of phosphorylationGO:00423252480.028
single organism catabolic processGO:00447122830.027
regulation of protein complex assemblyGO:0043254330.027
positive regulation of cell migrationGO:0030335960.027
reproductionGO:00000032450.027
protein localization to organelleGO:0033365570.027
regulation of immune response to tumor cellGO:000283730.027
regulation of anatomical structure morphogenesisGO:00226031410.027
blood circulationGO:00080151830.026
cellular carbohydrate metabolic processGO:0044262720.026
positive regulation of signal transductionGO:00099671750.026
cellular macromolecule localizationGO:00707271220.026
sister chromatid segregationGO:000081910.026
reactive oxygen species biosynthetic processGO:190340980.026
regulation of protein localizationGO:0032880810.026
regulation of kinase activityGO:00435491170.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
inflammatory responseGO:00069541500.025
positive regulation of catalytic activityGO:00430851840.025
cellular response to hypoxiaGO:0071456510.025
ubiquitin dependent protein catabolic processGO:0006511140.025
regulation of smooth muscle cell proliferationGO:0048660750.025
developmental process involved in reproductionGO:00030061590.025
g protein coupled receptor signaling pathwayGO:00071862420.024
positive regulation of protein phosphorylationGO:00019341350.024
positive regulation of protein metabolic processGO:00512471780.024
carboxylic acid biosynthetic processGO:0046394830.024
natural killer cell mediated immune response to tumor cellGO:000242310.024
positive regulation of immunoglobulin productionGO:000263940.024
transmembrane transportGO:00550854120.024
positive regulation of signalingGO:00230562700.024
cellular response to organic cyclic compoundGO:00714072020.023
single organism biosynthetic processGO:00447113420.023
peptidyl tyrosine phosphorylationGO:0018108720.023
anterior posterior pattern specificationGO:000995210.023
response to antibioticGO:0046677390.023
secretionGO:00469033070.023
response to uv cGO:001022520.023
cellular homeostasisGO:00197252520.023
double strand break repairGO:000630210.023
organonitrogen compound biosynthetic processGO:19015661670.023
secretion by cellGO:00329402480.023
negative regulation of actin filament polymerizationGO:003083740.023
positive regulation of transcription dna templatedGO:00458931970.023
negative regulation of neuron deathGO:1901215690.023
protein modification by small protein conjugation or removalGO:0070647350.022
positive regulation of protein modification processGO:00314011420.022
motor neuron axon guidanceGO:000804510.022
positive regulation of phosphate metabolic processGO:00459372620.022
regulation of dendrite developmentGO:0050773590.022
regulation of reactive oxygen species metabolic processGO:2000377260.022
regulation of hydrolase activityGO:00513361430.022
organic acid transportGO:00158491160.022
striated muscle contractionGO:0006941440.022
exocytosisGO:0006887600.022
macromolecule catabolic processGO:0009057580.022
regulation of cell motilityGO:20001451310.022
cellular response to oxygen levelsGO:0071453600.021
regulation of reactive oxygen species biosynthetic processGO:190342650.021
embryo developmentGO:0009790490.021
Mouse
regulation of cysteine type endopeptidase activityGO:2000116320.021
cell migrationGO:00164771970.021
kidney mesenchyme developmentGO:007207420.020
embryonic pattern specificationGO:000988010.020
response to osmotic stressGO:0006970420.020
myoblast fusionGO:000752020.020
embryonic axis specificationGO:000057810.020
cell cycleGO:00070491010.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281310.020
nucleocytoplasmic transportGO:0006913480.020
cellular response to oxygen containing compoundGO:19017013860.020
positive regulation of phosphorus metabolic processGO:00105622620.019
cardiovascular system developmentGO:00723581340.019
central nervous system developmentGO:00074173110.019
cellular component biogenesisGO:00440853680.019
organelle localizationGO:0051640550.019
protein deubiquitinationGO:001657940.019
positive regulation of programmed cell deathGO:00430681570.019
regulation of carbohydrate metabolic processGO:0006109410.019
regulation of cytoskeleton organizationGO:0051493490.019
regulation of rna biosynthetic processGO:20011413810.019
positive regulation of molecular functionGO:00440932300.019
positive regulation of cell deathGO:00109421840.018
multicellular organismal signalingGO:0035637440.018
purine ribonucleoside biosynthetic processGO:0046129210.018
gamete generationGO:00072761240.018
vesicle mediated transportGO:00161921810.018
protein modification by small protein conjugationGO:0032446310.018
protein processingGO:0016485680.018
regulation of developmental growthGO:0048638450.018
neuromuscular processGO:005090520.018
glutathione metabolic processGO:0006749150.018
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243630.018
negative regulation of gene expressionGO:00106291990.018
positive regulation of cellular component organizationGO:00511302000.018
carbohydrate derivative metabolic processGO:19011353460.018
regulation of membrane potentialGO:00423911100.018
cellular ion homeostasisGO:00068731840.018
negative regulation of molecular functionGO:00440921330.017
response to carbohydrateGO:00097431830.017
chemical homeostasisGO:00488782920.017
developmental growthGO:00485891000.017
cell projection morphogenesisGO:00488581230.017
lipid localizationGO:0010876620.017
regulation of stem cell differentiationGO:200073620.017
protein transportGO:00150311320.017
ion homeostasisGO:00508012120.017
lipid storageGO:001991510.017
positive regulation of cellular protein metabolic processGO:00322701670.017
cation homeostasisGO:00550801950.017
positive regulation of catabolic processGO:0009896780.017
epithelium developmentGO:0060429960.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.017
small gtpase mediated signal transductionGO:0007264360.016
ribonucleotide metabolic processGO:00092592310.016
membrane organizationGO:0061024940.016
axis specificationGO:000979840.016
actin filament based processGO:0030029860.016
dephosphorylationGO:0016311980.016
response to growth factorGO:00708481890.016
regulation of metal ion transportGO:00109591180.016
cytoskeleton dependent cytokinesisGO:006164020.016
ras protein signal transductionGO:0007265290.016
response to estrogenGO:00436272320.016
regulation of anatomical structure sizeGO:00900661350.015
organic cyclic compound catabolic processGO:19013611750.015
positive regulation of proteasomal protein catabolic processGO:190180030.015
response to isoquinoline alkaloidGO:0014072280.015
response to inorganic substanceGO:00100353770.015
cellular response to hormone stimulusGO:00328702470.015
endoplasmic reticulum unfolded protein responseGO:003096820.015
mitotic sister chromatid segregationGO:000007010.015
regulation of cellular amine metabolic processGO:003323880.015
neuron projection developmentGO:00311752730.015
microtubule based processGO:0007017360.015
transmission of nerve impulseGO:0019226420.015
leukocyte activation involved in immune responseGO:0002366160.015
muscle system processGO:00030121150.015
organic hydroxy compound metabolic processGO:19016151150.015
alternative mrna splicing via spliceosomeGO:000038040.015
neurological system processGO:00508772190.015
localization of cellGO:00516742020.015
glycosyl compound metabolic processGO:19016571820.015
rna metabolic processGO:00160704060.014
chromosome localizationGO:005000010.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
chromosome organizationGO:0051276360.014
positive regulation of adherens junction organizationGO:190339320.014
cation transportGO:00068123820.014
organic anion transportGO:00157111320.014
cellular component assemblyGO:00226073600.014
microtubule cytoskeleton organizationGO:0000226250.014
negative regulation of cell proliferationGO:00082851190.014
cellular response to steroid hormone stimulusGO:0071383930.014
cellular response to abiotic stimulusGO:0071214850.014
intracellular protein transportGO:0006886790.014
reactive nitrogen species metabolic processGO:200105710.014
positive regulation of protein kinase activityGO:0045860730.014
positive regulation of jnk cascadeGO:0046330130.014
regulation of intracellular transportGO:0032386650.014
protein oligomerizationGO:00512591910.014
phospholipid metabolic processGO:0006644610.014
regulation of locomotionGO:00400121480.013
epithelial cell differentiationGO:0030855710.013
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.013
single organism nuclear importGO:1902593350.013
nucleotide metabolic processGO:00091172790.013
response to ionizing radiationGO:0010212590.013
smad protein complex assemblyGO:000718310.013
cellular macromolecular complex assemblyGO:0034622580.013
cellular response to dna damage stimulusGO:0006974190.013
cellular response to hydrogen peroxideGO:0070301420.013
vesicle organizationGO:0016050290.013
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278730.013
purine nucleoside monophosphate biosynthetic processGO:0009127200.013
regulation of catabolic processGO:00098941130.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
regulation of glucocorticoid biosynthetic processGO:003194610.013
negative regulation of macromolecule metabolic processGO:00106052600.013
tissue homeostasisGO:0001894280.013
negative regulation of cellular metabolic processGO:00313242810.012
positive regulation of apoptotic processGO:00430651540.012
positive regulation of protein import into nucleus translocationGO:003316070.012
cellular component morphogenesisGO:00329891550.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012
cellular component movementGO:00069282480.012
insulin receptor signaling pathwayGO:0008286240.012
immune responseGO:00069551040.012
cytoplasmic transportGO:00164821150.012
positive regulation of cellular component movementGO:00512721020.012
cellular ketone metabolic processGO:0042180510.012
male gamete generationGO:0048232990.012
regulation of endopeptidase activityGO:0052548510.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
arp2 3 complex mediated actin nucleationGO:003431420.012
regulation of actin filament depolymerizationGO:003083420.012
purine ribonucleoside monophosphate metabolic processGO:0009167840.012
regulation of secretion by cellGO:19035302080.012
rna catabolic processGO:000640130.012
establishment of chromosome localizationGO:005130310.012
steroid biosynthetic processGO:0006694480.012
response to morphineGO:0043278270.012
regulation of proteasomal protein catabolic processGO:006113640.012
regulation of system processGO:00440572080.012
regulation of cellular amino acid metabolic processGO:000652120.012
regulation of cellular carbohydrate metabolic processGO:0010675390.012
cell part morphogenesisGO:00329901230.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
behaviorGO:00076102050.011
response to gonadotropinGO:0034698340.011
anatomical structure homeostasisGO:0060249290.011
heterocycle catabolic processGO:00467001670.011
purine containing compound metabolic processGO:00725212530.011
positive regulation of humoral immune responseGO:000292220.011
cellular amine metabolic processGO:0044106380.011
protein homooligomerizationGO:0051260910.011
cell cell signalingGO:00072673350.011
metal ion homeostasisGO:00550651860.011
regulation of alternative mrna splicing via spliceosomeGO:000038120.011
positive regulation of alkaline phosphatase activityGO:001069420.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
spermatogenesisGO:0007283990.011
cellular response to nutrientGO:0031670300.011
positive regulation of developmental growthGO:0048639290.011
negative regulation of cell communicationGO:00106481580.011
microtubule anchoringGO:003445310.011
positive regulation of t cell mediated cytotoxicityGO:000191640.011
regulation of cell differentiationGO:00455953200.011
protein localization to nucleusGO:0034504390.011
cellular response to growth factor stimulusGO:00713631620.011
syncytium formation by plasma membrane fusionGO:000076830.011
negative regulation of peptidase activityGO:0010466380.011
synaptic transmissionGO:00072682350.011
positive regulation of natural killer cell mediated immunityGO:000271720.011
wound healingGO:00420601220.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.010
response to axon injuryGO:0048678590.010
organonitrogen compound catabolic processGO:19015651790.010
activation of cysteine type endopeptidase activity involved in apoptotic processGO:000691940.010
vitamin d metabolic processGO:004235940.010
proteolysis involved in cellular protein catabolic processGO:0051603190.010
cellular macromolecule catabolic processGO:0044265290.010
single organism membrane organizationGO:0044802740.010
regulation of neuron differentiationGO:00456642080.010
positive regulation of transcription factor import into nucleusGO:004299340.010
muscle contractionGO:0006936880.010

Txnrd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.081
nervous system diseaseDOID:86300.081
central nervous system diseaseDOID:33100.026
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010