Rattus norvegicus

34 known processes

Cplx1

complexin 1

Cplx1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic vesicle endocytosisGO:004848840.503
positive regulation of cell communicationGO:00106472710.402
cellular component assemblyGO:00226073600.383
cellular component biogenesisGO:00440853680.376
macromolecular complex subunit organizationGO:00439333390.335
regulation of synaptic transmissionGO:00508041410.313
vesicle mediated transportGO:00161921810.313
protein complex biogenesisGO:00702712630.275
secretionGO:00469033070.267
regulation of secretionGO:00510462240.258
regulation of cellular component organizationGO:00511283680.255
neuron projection developmentGO:00311752730.250
cell cell signalingGO:00072673350.248
regulation of cellular localizationGO:00603412630.245
synaptic vesicle docking involved in exocytosisGO:001608120.240
neurotransmitter secretionGO:0007269330.239
positive regulation of secretion by cellGO:19035321280.235
neuron differentiationGO:00301823680.233
macromolecular complex assemblyGO:00650032730.223
neuron apoptotic processGO:0051402880.223
synaptic transmissionGO:00072682350.222
exocytosisGO:0006887600.221
positive regulation of neurotransmitter secretionGO:000195690.221
regulation of cell projection organizationGO:00313441750.206
neuron developmentGO:00486662860.203
establishment of vesicle localizationGO:0051650310.203
regulation of cell developmentGO:00602842630.196
regulation of vesicle mediated transportGO:0060627810.191
protein complex subunit organizationGO:00718223020.189
synaptic vesicle primingGO:001608240.178
regulation of exocytosisGO:0017157370.177
establishment of organelle localizationGO:0051656370.175
protein complex assemblyGO:00064612630.172
macromolecule localizationGO:00330362520.162
regulation of secretion by cellGO:19035302080.161
vesicle fusionGO:0006906140.157
synaptic vesicle exocytosisGO:0016079150.151
positive regulation of multicellular organismal processGO:00512403870.151
regulation of neurotransmitter levelsGO:0001505420.145
signal releaseGO:00230611450.138
cellular component movementGO:00069282480.137
reproductive processGO:00224143720.130
response to hypoxiaGO:00016662310.127
action potentialGO:0001508540.122
regulation of multicellular organismal developmentGO:20000263760.117
regulation of neuron apoptotic processGO:0043523830.115
cellular response to organonitrogen compoundGO:00714171970.115
response to alkaloidGO:00432791320.113
cation transportGO:00068123820.107
phosphatidylinositol dephosphorylationGO:004685640.107
regulation of nervous system developmentGO:00519602640.103
establishment of protein localizationGO:00451841410.102
neuron deathGO:00709971270.101
organelle localizationGO:0051640550.099
positive regulation of secretionGO:00510471400.097
regulation of neurotransmitter secretionGO:0046928190.097
positive regulation of cell differentiationGO:00455972170.095
regulation of membrane potentialGO:00423911100.095
response to inorganic substanceGO:00100353770.094
positive regulation of exocytosisGO:0045921190.093
positive regulation of signalingGO:00230562700.090
protein transportGO:00150311320.090
regulation of neurogenesisGO:00507672470.086
vesicle localizationGO:0051648330.086
membrane fusionGO:0061025260.085
membrane organizationGO:0061024940.083
axon developmentGO:0061564960.082
regulation of neuron differentiationGO:00456642080.082
response to peptide hormoneGO:00434342780.081
cellular response to endogenous stimulusGO:00714953770.078
regulation of synaptic vesicle exocytosisGO:200030060.077
calcium ion transportGO:00068161310.076
synaptic vesicle localizationGO:0097479240.075
cellular homeostasisGO:00197252520.075
muscle system processGO:00030121150.074
taxisGO:0042330670.074
schwann cell migrationGO:003613520.072
vesicle dockingGO:004827850.072
response to mechanical stimulusGO:00096121340.071
neurotransmitter transportGO:0006836420.071
multi organism reproductive processGO:00447032620.071
positive regulation of transportGO:00510502450.071
reproductionGO:00000032450.070
regulation of cell proliferationGO:00421273590.068
response to peptideGO:19016522920.068
single organism reproductive processGO:00447022970.068
axonogenesisGO:0007409710.067
positive regulation of response to stimulusGO:00485842850.065
neuromuscular synaptic transmissionGO:000727420.065
cell morphogenesis involved in neuron differentiationGO:00486671060.063
cell motilityGO:00488702020.063
cell part morphogenesisGO:00329901230.063
synapse organizationGO:0050808460.063
synaptic vesicle transportGO:0048489230.062
response to extracellular stimulusGO:00099913800.062
cellular ion homeostasisGO:00068731840.062
regulation of synaptic vesicle transportGO:190280360.061
single organism biosynthetic processGO:00447113420.060
regulation of neuron projection developmentGO:00109751610.060
neuron projection morphogenesisGO:00488121220.058
secretion by cellGO:00329402480.058
regulation of molecular functionGO:00650093980.058
behaviorGO:00076102050.057
regulation of axonogenesisGO:0050770370.056
cellular response to nitrogen compoundGO:19016992100.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
positive regulation of cell projection organizationGO:00313461110.055
multicellular organismal reproductive processGO:00486092330.054
protein oligomerizationGO:00512591910.054
protein localizationGO:00081041910.054
cellular macromolecule localizationGO:00707271220.054
cell cycleGO:00070491010.053
response to growth factorGO:00708481890.053
calcium ion dependent exocytosis of neurotransmitterGO:004879120.052
muscle contractionGO:0006936880.052
single organism intracellular transportGO:19025821660.052
monocarboxylic acid transportGO:0015718520.052
positive regulation of hydrolase activityGO:0051345860.051
organonitrogen compound biosynthetic processGO:19015661670.050
response to nutrient levelsGO:00316673700.050
regulation of neuron deathGO:19012141150.049
metal ion transportGO:00300012890.048
regulation of catalytic activityGO:00507903040.047
cell projection organizationGO:00300303020.047
intracellular protein transportGO:0006886790.047
single organism membrane fusionGO:0044801170.047
cellular response to organic cyclic compoundGO:00714072020.046
response to nutrientGO:00075842480.046
intracellular transportGO:00469071850.045
locomotionGO:00400112370.045
cellular response to oxygen containing compoundGO:19017013860.044
positive regulation of phosphate metabolic processGO:00459372620.044
response to vitaminGO:00332731310.044
neurological system processGO:00508772190.044
regulation of phosphorus metabolic processGO:00511743490.043
hormone secretionGO:00468791150.043
peptide secretionGO:0002790860.042
positive regulation of cellular component organizationGO:00511302000.042
cellular protein localizationGO:00346131220.042
regulation of cell differentiationGO:00455953200.041
g protein coupled receptor signaling pathwayGO:00071862420.041
axis specificationGO:000979840.041
response to monosaccharideGO:00342841590.041
cellular amino acid biosynthetic processGO:0008652320.041
positive regulation of neuron projection developmentGO:0010976990.041
establishment of synaptic vesicle localizationGO:0097480230.040
positive regulation of phosphorus metabolic processGO:00105622620.040
response to external biotic stimulusGO:00432072210.039
monovalent inorganic cation transportGO:00156721720.039
defecationGO:003042110.039
immune system processGO:00023762040.039
cellular response to peptideGO:19016531330.038
organic substance catabolic processGO:19015753160.038
response to molecule of bacterial originGO:00022371940.038
endocytosisGO:0006897840.038
multicellular organism reproductionGO:00325042330.037
intracellular signal transductionGO:00355563140.037
cellular amino acid metabolic processGO:00065201070.037
response to glucoseGO:00097491360.037
potassium ion transportGO:0006813970.037
cellular response to growth factor stimulusGO:00713631620.036
regulation of signal transductionGO:00099663180.036
second messenger mediated signalingGO:0019932510.036
response to carbohydrateGO:00097431830.036
negative regulation of vesicle fusionGO:003133920.036
response to calcium ionGO:0051592590.036
organelle organizationGO:00069962660.036
positive regulation of developmental processGO:00510942830.035
blood circulationGO:00080151830.035
embryonic axis specificationGO:000057810.035
positive regulation of catalytic activityGO:00430851840.035
regulation of locomotionGO:00400121480.035
synaptic growth at neuromuscular junctionGO:005112410.034
organelle fusionGO:0048284170.034
cellular response to external stimulusGO:00714961180.034
positive regulation of cell developmentGO:00107201760.033
positive regulation of nucleotide metabolic processGO:0045981910.033
single organism catabolic processGO:00447122830.032
chemotaxisGO:0006935660.032
cell type specific apoptotic processGO:00972851340.032
negative regulation of cell deathGO:00605482290.032
response to cytokineGO:00340972150.032
cellular component morphogenesisGO:00329891550.032
regulation of intracellular signal transductionGO:19025312180.031
positive regulation of synaptic transmissionGO:0050806620.031
neuromuscular processGO:005090520.031
membrane dockingGO:002240660.031
reproductive structure developmentGO:00486081280.031
purinergic receptor signaling pathwayGO:0035587100.031
negative regulation of programmed cell deathGO:00430691830.031
cellular metal ion homeostasisGO:00068751720.031
regulation of protein metabolic processGO:00512462890.030
response to hydrogen peroxideGO:0042542890.030
ribose phosphate metabolic processGO:00196932350.030
transmission of nerve impulseGO:0019226420.030
cytoplasmic transportGO:00164821150.030
cellular macromolecular complex assemblyGO:0034622580.029
anterior posterior pattern specificationGO:000995210.029
positive regulation of cytosolic calcium ion concentrationGO:00072041220.029
regulation of immune system processGO:00026821230.029
divalent inorganic cation transportGO:00725111340.029
regulation of anatomical structure sizeGO:00900661350.029
positive regulation of neurogenesisGO:00507691650.029
regulation of phosphatidylinositol dephosphorylationGO:006030410.028
negative regulation of cell communicationGO:00106481580.028
response to lipopolysaccharideGO:00324961910.028
response to histamineGO:003477630.028
response to nicotineGO:0035094510.028
nucleoside phosphate metabolic processGO:00067532830.028
single organism membrane organizationGO:0044802740.028
leukocyte migrationGO:0050900380.027
response to toxic substanceGO:00096361330.027
negative regulation of ion transmembrane transporter activityGO:0032413120.027
brain developmentGO:00074202470.027
response to woundingGO:00096112540.027
intermediate filament bundle assemblyGO:004511010.027
response to estrogenGO:00436272320.027
calcium ion dependent exocytosisGO:0017156160.027
positive regulation of hormone secretionGO:0046887650.027
nucleobase containing small molecule metabolic processGO:00550863160.026
embryonic pattern specificationGO:000988010.026
response to estradiolGO:00323551640.026
single organism cellular localizationGO:19025801020.026
single organism organelle organizationGO:19025891800.026
regulation of hormone levelsGO:00108171870.026
sexual reproductionGO:00199531480.026
response to insulinGO:00328681330.026
heart processGO:0003015570.026
circulatory system processGO:00030131830.025
vesicle organizationGO:0016050290.025
cellular response to abiotic stimulusGO:0071214850.025
negative regulation of neuron apoptotic processGO:0043524450.025
localization of cellGO:00516742020.025
amide transportGO:00428861050.025
cellular cation homeostasisGO:00300031800.025
response to oxidative stressGO:00069791860.024
heart morphogenesisGO:000300730.024
response to transition metal nanoparticleGO:19902671220.024
calcium ion transmembrane transportGO:0070588700.024
neuronal action potentialGO:0019228350.024
cellular response to stressGO:00335542690.024
catabolic processGO:00090563510.024
synaptic transmission glycinergicGO:006001220.024
intermediate filament based processGO:004510330.024
immune responseGO:00069551040.024
cell morphogenesis involved in differentiationGO:00009041190.024
cellular response to peptide hormone stimulusGO:00713751200.024
chemosensory behaviorGO:000763520.024
regulation of peptide transportGO:0090087870.023
response to ethanolGO:00454711620.023
vesicle docking involved in exocytosisGO:000690440.023
regulation of peptide secretionGO:0002791820.023
cellular response to insulin stimulusGO:0032869810.023
transmembrane transportGO:00550854120.023
cell morphogenesisGO:00009021420.023
positive regulation of calcium ion dependent exocytosisGO:004595660.023
positive regulation of cell proliferationGO:00082842490.023
positive regulation of intracellular signal transductionGO:19025331380.023
heterocycle catabolic processGO:00467001670.023
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057920.023
positive regulation of action potentialGO:004576080.023
cellular protein complex assemblyGO:0043623440.023
synaptic transmission cholinergicGO:0007271110.023
response to biotic stimulusGO:00096072260.022
regulation of ion transportGO:00432692450.022
sequestering of calcium ionGO:005120880.022
nucleotide metabolic processGO:00091172790.022
cellular response to hormone stimulusGO:00328702470.022
growthGO:00400071650.022
cellular response to lipidGO:00713962010.022
positive regulation of purine nucleotide metabolic processGO:1900544910.022
response to hexoseGO:00097461440.022
hormone transportGO:00099141210.022
regulation of purine nucleotide metabolic processGO:19005421150.022
regulation of cell projection sizeGO:003253610.021
protein homooligomerizationGO:0051260910.021
regulation of nucleotide biosynthetic processGO:0030808470.021
regulation of phosphorylationGO:00423252480.021
positive regulation of neuron apoptotic processGO:0043525330.021
divalent metal ion transportGO:00708381320.021
response to oxygen levelsGO:00704822650.021
regulation of apoptotic processGO:00429813350.021
actin filament organizationGO:0007015420.021
purine containing compound metabolic processGO:00725212530.020
ras protein signal transductionGO:0007265290.020
response to decreased oxygen levelsGO:00362932370.020
actin filament based processGO:0030029860.020
protein heterooligomerizationGO:0051291890.020
regulation of metal ion transportGO:00109591180.020
positive regulation of nervous system developmentGO:00519621780.020
positive regulation of neuron differentiationGO:00456661260.020
protein maturationGO:0051604680.020
homeostatic processGO:00425923310.020
regulation of blood circulationGO:19035221100.020
response to heatGO:0009408600.020
response to ammonium ionGO:0060359710.020
ion transmembrane transportGO:00342203650.020
anion transportGO:00068201780.020
positive regulation of molecular functionGO:00440932300.020
regulation of heart contractionGO:0008016480.020
lipid metabolic processGO:00066292830.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
negative regulation of metabolic processGO:00098923310.019
neuronal ion channel clusteringGO:004516130.019
anatomical structure morphogenesisGO:00096532980.019
carbohydrate derivative metabolic processGO:19011353460.019
axon cargo transportGO:000808810.019
regulation of regulated secretory pathwayGO:190330570.019
receptor mediated endocytosisGO:0006898420.019
developmental process involved in reproductionGO:00030061590.019
positive regulation of peptide hormone secretionGO:0090277500.019
head developmentGO:00603222470.019
response to light stimulusGO:0009416520.019
regulation of synapse structure and activityGO:0050803210.019
rna localizationGO:000640340.019
regulation of peptide hormone secretionGO:0090276800.019
regulation of cell migrationGO:00303341280.019
cation transmembrane transportGO:00986552630.018
regulation of hormone secretionGO:00468831060.018
peristalsisGO:003043220.018
peptide hormone secretionGO:0030072840.018
regulation of schwann cell migrationGO:190014720.018
negative regulation of protein metabolic processGO:00512481140.018
endoplasmic reticulum organizationGO:000702910.018
negative regulation of apoptotic processGO:00430661810.018
regulation of embryonic developmentGO:004599520.018
regulation of synaptic vesicle primingGO:001080730.018
cell projection morphogenesisGO:00488581230.018
regulation of synaptic plasticityGO:0048167700.017
response to reactive oxygen speciesGO:00003021200.017
positive regulation of nitrogen compound metabolic processGO:00511733340.017
gliogenesisGO:0042063930.017
cellular response to mechanical stimulusGO:0071260480.017
nucleoside phosphate biosynthetic processGO:19012931020.017
cellular response to histamineGO:007142030.017
ribonucleotide metabolic processGO:00092592310.017
apoptotic processGO:00069153810.017
sodium ion transmembrane transportGO:0035725670.017
regulation of phosphate metabolic processGO:00192203490.017
regulation of cellular component biogenesisGO:0044087860.017
response to activityGO:0014823730.017
synapse assemblyGO:0007416290.017
phasic smooth muscle contractionGO:001482130.017
cognitionGO:0050890920.017
single organism behaviorGO:00447081300.017
cellular ketone metabolic processGO:0042180510.016
vasoconstrictionGO:0042310540.016
motor neuron axon guidanceGO:000804510.016
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.016
detection of calcium ionGO:000551310.016
cellular chemical homeostasisGO:00550822470.016
negative regulation of neuron deathGO:1901215690.016
axon guidanceGO:0007411240.016
regulation of neurotransmitter transportGO:0051588210.016
organic anion transportGO:00157111320.016
heart contractionGO:0060047570.016
regulation of kinase activityGO:00435491170.016
regulation of nucleotide metabolic processGO:00061401170.015
purine ribonucleotide catabolic processGO:00091541360.015
cell migrationGO:00164771970.015
cellular calcium ion homeostasisGO:00068741600.015
negative regulation of purine nucleotide biosynthetic processGO:1900372120.015
regulation of cellular amine metabolic processGO:003323880.015
negative regulation of phosphorus metabolic processGO:0010563800.015
regulation of transporter activityGO:0032409500.015
cytoskeleton organizationGO:00070101110.015
regulation of tube sizeGO:0035150890.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
multicellular organismal signalingGO:0035637440.015
negative regulation of molecular functionGO:00440921330.015
olfactory behaviorGO:004204820.015
positive regulation of immune system processGO:0002684900.014
lipid modificationGO:0030258520.014
calcium mediated signalingGO:0019722230.014
positive regulation of cell activationGO:0050867340.014
regulation of immune responseGO:0050776550.014
activation of cysteine type endopeptidase activity involved in apoptotic processGO:000691940.014
regulation of cell motilityGO:20001451310.014
regulation of programmed cell deathGO:00430673410.014
positive regulation of gtp catabolic processGO:0033126480.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
organophosphate biosynthetic processGO:00904071430.014
chemical homeostasisGO:00488782920.014
regulation of cellular protein metabolic processGO:00322682670.014
response to acid chemicalGO:00011012220.014
adult locomotory behaviorGO:000834440.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
leptin mediated signaling pathwayGO:003321030.014
organic acid transportGO:00158491160.013
epithelium developmentGO:0060429960.013
small gtpase mediated signal transductionGO:0007264360.013
protein phosphorylationGO:00064683450.013
insulin secretionGO:0030073690.013
potassium ion homeostasisGO:005507520.013
regulation of intracellular transportGO:0032386650.013
regulation of insulin secretionGO:0050796650.013
regulation of response to external stimulusGO:00321011060.013
negative regulation of response to stimulusGO:00485851550.013
calcium ion homeostasisGO:00550741620.013
negative regulation of signalingGO:00230571570.013
cell activationGO:0001775970.013
regulation of ion transmembrane transporter activityGO:0032412480.013
positive regulation of neurotransmitter transportGO:005159090.013
agingGO:00075682410.013
activation of cysteine type endopeptidase activityGO:009720240.013
gamete generationGO:00072761240.013
regulation of cellular ketone metabolic processGO:0010565270.013
nitrogen compound transportGO:00717052290.013
positive regulation of synaptic vesicle recyclingGO:190342310.013
digestive tract developmentGO:0048565390.013
positive regulation of phosphorylationGO:00423271770.013
regulation of transferase activityGO:00513381230.013
response to vitamin dGO:0033280340.013
positive regulation of peptide secretionGO:0002793520.013
g protein coupled purinergic receptor signaling pathwayGO:003558880.013
positive regulation of locomotionGO:00400171020.012
regulation of protein phosphorylationGO:00019321830.012
neuron projection guidanceGO:0097485240.012
growth hormone secretionGO:003025280.012
response to corticosteroneGO:0051412400.012
regulated secretory pathwayGO:0045055170.012
cytokine secretionGO:0050663150.012
organonitrogen compound catabolic processGO:19015651790.012
regulation of blood vessel sizeGO:0050880890.012
purine ribonucleotide metabolic processGO:00091502270.012
negative regulation of catalytic activityGO:00430861030.012
membrane depolarization during cardiac muscle cell action potentialGO:008601210.012
purine nucleotide metabolic processGO:00061632290.012
activation of immune responseGO:0002253260.012
intermediate filament cytoskeleton organizationGO:004510430.012
regulation of muscle contractionGO:0006937530.012
cellular amine metabolic processGO:0044106380.012
sequestering of metal ionGO:005123890.012
regulation of organelle organizationGO:0033043800.011
regulation of vesicle fusionGO:003133860.011
negative regulation of signal transductionGO:0009968830.011
regulation of calcium ion dependent exocytosisGO:0017158110.011
inorganic cation transmembrane transportGO:00986622020.011
endoplasmic reticulum membrane organizationGO:009015810.011
negative regulation of cellular metabolic processGO:00313242810.011
actin cytoskeleton organizationGO:0030036730.011
cellular potassium ion homeostasisGO:003000710.011
negative regulation of transporter activityGO:0032410130.011
central nervous system developmentGO:00074173110.011
response to osmotic stressGO:0006970420.011
female gamete generationGO:0007292250.011
alpha amino acid biosynthetic processGO:1901607230.011
small molecule biosynthetic processGO:00442831240.011
regulation of leukocyte activationGO:0002694450.011
sodium ion exportGO:007143610.011
regulation of lipid metabolic processGO:0019216680.011
embryo developmentGO:0009790490.011
positive regulation of cell motilityGO:2000147970.011
regulation of postsynaptic membrane potentialGO:0060078250.011
ribose phosphate biosynthetic processGO:0046390870.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
negative regulation of adenylate cyclase activityGO:000719470.011
regulation of homeostatic processGO:00328441010.011
cyclic nucleotide metabolic processGO:0009187800.011
positive regulation of cellular amino acid metabolic processGO:004576410.010
intermediate filament organizationGO:004510910.010
programmed cell deathGO:00125013920.010
vitamin transportGO:0051180140.010
synaptic vesicle recyclingGO:003646550.010
peptide transportGO:0015833970.010
positive regulation of signal transductionGO:00099671750.010
positive regulation of vesicle fusionGO:003134040.010
norepinephrine metabolic processGO:004241530.010
glutamate receptor signaling pathwayGO:0007215430.010
positive regulation of cellular protein metabolic processGO:00322701670.010
endomembrane system organizationGO:0010256480.010
regulation of cellular component movementGO:00512701500.010
regulation of system processGO:00440572080.010
rhythmic synaptic transmissionGO:006002410.010
response to other organismGO:00517072200.010

Cplx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.089
disease of anatomical entityDOID:700.089
central nervous system diseaseDOID:33100.049
brain diseaseDOID:93600.012
epilepsy syndromeDOID:182600.012