Rattus norvegicus

19 known processes

Trim2

tripartite motif-containing 2

Trim2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component organizationGO:00511283680.203
regulation of signal transductionGO:00099663180.155
cellular component movementGO:00069282480.141
neuron differentiationGO:00301823680.104
positive regulation of response to stimulusGO:00485842850.098
positive regulation of cellular component organizationGO:00511302000.091
intracellular signal transductionGO:00355563140.079
cell morphogenesis involved in neuron differentiationGO:00486671060.073
neuron projection developmentGO:00311752730.070
regulation of nervous system developmentGO:00519602640.069
regulation of cell differentiationGO:00455953200.066
cellular component assemblyGO:00226073600.066
regulation of intracellular signal transductionGO:19025312180.063
regulation of multicellular organismal developmentGO:20000263760.063
central nervous system developmentGO:00074173110.063
positive regulation of nitrogen compound metabolic processGO:00511733340.062
positive regulation of developmental processGO:00510942830.061
positive regulation of multicellular organismal processGO:00512403870.060
cell projection organizationGO:00300303020.059
cellular response to stressGO:00335542690.057
regulation of cell developmentGO:00602842630.056
neuron developmentGO:00486662860.055
cell morphogenesis involved in differentiationGO:00009041190.055
regulation of neuron projection developmentGO:00109751610.051
anatomical structure morphogenesisGO:00096532980.051
regulation of programmed cell deathGO:00430673410.050
multicellular organismal signalingGO:0035637440.050
regulation of neurogenesisGO:00507672470.049
regulation of cellular ketone metabolic processGO:0010565270.049
cell morphogenesisGO:00009021420.049
intracellular transportGO:00469071850.048
cellular component biogenesisGO:00440853680.048
regulation of protein metabolic processGO:00512462890.048
locomotionGO:00400112370.047
positive regulation of nucleobase containing compound metabolic processGO:00459353190.047
regulation of cell projection organizationGO:00313441750.046
brain developmentGO:00074202470.046
regulation of phosphorylationGO:00423252480.045
cell part morphogenesisGO:00329901230.044
protein phosphorylationGO:00064683450.044
carboxylic acid metabolic processGO:00197522890.044
regulation of phosphate metabolic processGO:00192203490.043
organic acid metabolic processGO:00060822920.041
regulation of molecular functionGO:00650093980.041
positive regulation of cellular biosynthetic processGO:00313282950.041
protein complex assemblyGO:00064612630.040
positive regulation of cell communicationGO:00106472710.040
positive regulation of cell developmentGO:00107201760.039
rna metabolic processGO:00160704060.039
cellular amino acid metabolic processGO:00065201070.039
response to purine containing compoundGO:00140741260.039
regulation of apoptotic processGO:00429813350.039
regulation of neuron differentiationGO:00456642080.038
negative regulation of signalingGO:00230571570.038
reproductive processGO:00224143720.038
positive regulation of cell differentiationGO:00455972170.037
positive regulation of neurogenesisGO:00507691650.037
protein complex biogenesisGO:00702712630.037
regulation of catalytic activityGO:00507903040.036
enzyme linked receptor protein signaling pathwayGO:00071671160.036
cellular component morphogenesisGO:00329891550.036
regulation of cellular amino acid metabolic processGO:000652120.035
cellular response to oxygen containing compoundGO:19017013860.035
positive regulation of signalingGO:00230562700.035
carbohydrate derivative metabolic processGO:19011353460.035
regulation of transcription dna templatedGO:00063553740.034
regulation of proteasomal protein catabolic processGO:006113640.034
regulation of cell proliferationGO:00421273590.034
response to growth factorGO:00708481890.034
dendrite morphogenesisGO:0048813430.033
programmed cell deathGO:00125013920.033
lipid metabolic processGO:00066292830.033
nucleobase containing small molecule metabolic processGO:00550863160.033
positive regulation of biosynthetic processGO:00098913190.033
neurological system processGO:00508772190.032
positive regulation of cell projection organizationGO:00313461110.032
neurotrophin signaling pathwayGO:0038179180.032
cell migrationGO:00164771970.031
nucleoside phosphate metabolic processGO:00067532830.031
neuron projection morphogenesisGO:00488121220.031
head developmentGO:00603222470.031
protein complex subunit organizationGO:00718223020.031
reproductionGO:00000032450.031
regulation of phosphorus metabolic processGO:00511743490.031
organelle organizationGO:00069962660.031
protein localizationGO:00081041910.030
macromolecule localizationGO:00330362520.030
response to peptideGO:19016522920.030
organophosphate metabolic processGO:00196373700.030
cellular amine metabolic processGO:0044106380.029
localization of cellGO:00516742020.029
negative regulation of cell communicationGO:00106481580.029
rna biosynthetic processGO:00327743800.029
action potentialGO:0001508540.029
cellular ketone metabolic processGO:0042180510.029
growthGO:00400071650.028
motor neuron axon guidanceGO:000804510.028
cellular response to growth factor stimulusGO:00713631620.028
positive regulation of nervous system developmentGO:00519621780.028
regulation of cellular amine metabolic processGO:003323880.028
apoptotic processGO:00069153810.028
organic substance catabolic processGO:19015753160.027
negative regulation of response to stimulusGO:00485851550.027
regulation of nucleic acid templated transcriptionGO:19035063800.027
transmission of nerve impulseGO:0019226420.027
catabolic processGO:00090563510.026
g protein coupled receptor signaling pathwayGO:00071862420.026
glycosyl compound catabolic processGO:19016581260.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.026
mapk cascadeGO:00001651400.026
regulation of cell morphogenesisGO:0022604770.026
regulation of rna biosynthetic processGO:20011413810.026
positive regulation of neuron projection developmentGO:0010976990.026
regulation of locomotionGO:00400121480.026
response to peptide hormoneGO:00434342780.026
oxoacid metabolic processGO:00434362900.026
single organism intracellular transportGO:19025821660.026
positive regulation of phosphate metabolic processGO:00459372620.026
regulation of rna metabolic processGO:00512523910.025
response to extracellular stimulusGO:00099913800.025
purine ribonucleotide metabolic processGO:00091502270.025
neuronal action potentialGO:0019228350.025
positive regulation of transportGO:00510502450.025
purine containing compound catabolic processGO:00725231380.025
regulation of protein phosphorylationGO:00019321830.024
positive regulation of signal transductionGO:00099671750.024
multicellular organism growthGO:003526410.024
chemical homeostasisGO:00488782920.024
macromolecular complex assemblyGO:00650032730.024
regulation of cellular protein metabolic processGO:00322682670.024
ion homeostasisGO:00508012120.024
purine containing compound metabolic processGO:00725212530.024
positive regulation of phosphorus metabolic processGO:00105622620.023
positive regulation of transcription dna templatedGO:00458931970.023
positive regulation of gene expressionGO:00106282440.023
macromolecular complex subunit organizationGO:00439333390.023
response to nutrient levelsGO:00316673700.023
cation transportGO:00068123820.023
positive regulation of catalytic activityGO:00430851840.023
amine metabolic processGO:0009308380.023
cell projection morphogenesisGO:00488581230.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
carbohydrate derivative biosynthetic processGO:19011371240.022
myelinationGO:0042552390.022
signal transduction by phosphorylationGO:00230141440.022
ribose phosphate metabolic processGO:00196932350.022
cellular response to nitrogen compoundGO:19016992100.022
negative regulation of signal transductionGO:0009968830.022
cellular response to organonitrogen compoundGO:00714171970.022
ion transmembrane transportGO:00342203650.021
transcription dna templatedGO:00063513770.021
dendrite developmentGO:0016358720.021
purine ribonucleoside triphosphate metabolic processGO:00092051400.021
positive regulation of neuron differentiationGO:00456661260.021
retinal ganglion cell axon guidanceGO:003129010.021
nucleoside phosphate catabolic processGO:19012921400.020
single organism reproductive processGO:00447022970.020
regulation of ion transportGO:00432692450.020
single organism cellular localizationGO:19025801020.020
negative regulation of macromolecule metabolic processGO:00106052600.020
positive regulation of apoptotic processGO:00430651540.020
cellular response to endogenous stimulusGO:00714953770.020
behaviorGO:00076102050.020
single organism biosynthetic processGO:00447113420.020
response to oxygen levelsGO:00704822650.019
response to oxidative stressGO:00069791860.019
cation homeostasisGO:00550801950.019
multi organism reproductive processGO:00447032620.019
homeostatic processGO:00425923310.019
negative regulation of metabolic processGO:00098923310.019
cell adhesionGO:00071551100.019
purine ribonucleoside metabolic processGO:00461281680.019
metal ion transportGO:00300012890.019
divalent metal ion transportGO:00708381320.019
axon developmentGO:0061564960.019
regulation of cell migrationGO:00303341280.019
positive regulation of rna biosynthetic processGO:19026801970.019
ribonucleoside triphosphate metabolic processGO:00091991410.019
cell motilityGO:00488702020.019
regulation of catabolic processGO:00098941130.019
regulation of cell cycleGO:0051726730.019
negative regulation of programmed cell deathGO:00430691830.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
regulation of transferase activityGO:00513381230.018
response to metal ionGO:00100382530.018
transmembrane transportGO:00550854120.018
regulation of growthGO:00400081050.018
cellular homeostasisGO:00197252520.018
negative regulation of cell deathGO:00605482290.018
organonitrogen compound catabolic processGO:19015651790.018
biological adhesionGO:00226101100.018
multicellular organismal reproductive processGO:00486092330.018
protein transportGO:00150311320.018
regulation of hydrolase activityGO:00513361430.018
positive regulation of molecular functionGO:00440932300.018
negative regulation of apoptotic processGO:00430661810.018
positive regulation of intracellular signal transductionGO:19025331380.017
cellular response to organic cyclic compoundGO:00714072020.017
tissue developmentGO:00098882520.017
nucleoside triphosphate catabolic processGO:00091431230.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
response to acid chemicalGO:00011012220.017
synaptic growth at neuromuscular junctionGO:005112410.017
organophosphate catabolic processGO:00464341480.017
single organism organelle organizationGO:19025891800.017
carbohydrate derivative catabolic processGO:19011361470.017
multicellular organism reproductionGO:00325042330.017
regulation of vesicle mediated transportGO:0060627810.017
developmental growthGO:00485891000.017
positive regulation of phosphorylationGO:00423271770.017
regulation of cell growthGO:0001558850.017
dephosphorylationGO:0016311980.017
cellular chemical homeostasisGO:00550822470.017
regulation of response to stressGO:00801341260.017
positive regulation of cellular protein metabolic processGO:00322701670.017
transcription from rna polymerase ii promoterGO:00063662520.017
cell cycleGO:00070491010.017
nucleic acid templated transcriptionGO:00976593790.017
divalent inorganic cation homeostasisGO:00725071650.017
regulation of protein modification processGO:00313991940.016
regulation of membrane potentialGO:00423911100.016
response to inorganic substanceGO:00100353770.016
ribonucleotide catabolic processGO:00092611360.016
cellular metal ion homeostasisGO:00068751720.016
positive regulation of protein phosphorylationGO:00019341350.016
metal ion homeostasisGO:00550651860.016
ribonucleotide metabolic processGO:00092592310.016
secretionGO:00469033070.016
positive regulation of cellular amine metabolic processGO:003324030.016
nucleoside metabolic processGO:00091161790.016
monovalent inorganic cation transportGO:00156721720.016
calcium ion transportGO:00068161310.016
response to nutrientGO:00075842480.016
regulation of dendrite morphogenesisGO:0048814330.016
cytoplasmic transportGO:00164821150.016
forebrain developmentGO:0030900980.016
purine ribonucleotide catabolic processGO:00091541360.016
negative regulation of cell proliferationGO:00082851190.016
cellular catabolic processGO:00442482950.016
negative regulation of multicellular organismal processGO:00512412030.015
ras protein signal transductionGO:0007265290.015
glycosyl compound metabolic processGO:19016571820.015
memoryGO:0007613540.015
cellular lipid metabolic processGO:00442552080.015
establishment of protein localizationGO:00451841410.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
carbohydrate metabolic processGO:00059751300.015
response to cytokineGO:00340972150.015
inorganic cation transmembrane transportGO:00986622020.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
learning or memoryGO:0007611900.015
nucleotide metabolic processGO:00091172790.015
regulation of sodium ion transmembrane transporter activityGO:200064940.015
purine nucleotide metabolic processGO:00061632290.015
nucleobase containing compound catabolic processGO:00346551520.015
negative regulation of cell developmentGO:0010721820.015
positive regulation of cell deathGO:00109421840.015
regulation of homeostatic processGO:00328441010.015
cell type specific apoptotic processGO:00972851340.015
agingGO:00075682410.015
sexual reproductionGO:00199531480.015
regulation of anatomical structure sizeGO:00900661350.015
ribonucleoside metabolic processGO:00091191740.015
regulation of dendrite developmentGO:0050773590.015
regulation of cell motilityGO:20001451310.015
regulation of purine nucleotide metabolic processGO:19005421150.014
positive regulation of programmed cell deathGO:00430681570.014
cell growthGO:00160491040.014
sex differentiationGO:00075481130.014
regulation of cellular component movementGO:00512701500.014
regulation of protein kinase activityGO:00458591050.014
regulation of canonical wnt signaling pathwayGO:006082840.014
negative regulation of nervous system developmentGO:0051961790.014
positive regulation of protein modification processGO:00314011420.014
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.014
small gtpase mediated signal transductionGO:0007264360.014
response to ketoneGO:19016541820.014
protein heterooligomerizationGO:0051291890.014
purine nucleotide catabolic processGO:00061951360.014
protein oligomerizationGO:00512591910.014
regulation of synaptic transmissionGO:00508041410.014
regulation of nucleotide metabolic processGO:00061401170.014
regulation of cellular catabolic processGO:00313291010.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
regulation of anatomical structure morphogenesisGO:00226031410.014
negative regulation of cellular metabolic processGO:00313242810.014
regulation of metal ion transportGO:00109591180.014
dna metabolic processGO:0006259960.014
proteolysisGO:00065081750.014
divalent inorganic cation transportGO:00725111340.014
nucleoside catabolic processGO:00091641260.014
cellular response to lipidGO:00713962010.014
cardiovascular system developmentGO:00723581340.014
cellular macromolecule localizationGO:00707271220.013
development of primary sexual characteristicsGO:00451371070.013
regulation of kinase activityGO:00435491170.013
response to organophosphorusGO:00466831020.013
cellular protein localizationGO:00346131220.013
regulation of nucleoside metabolic processGO:0009118660.013
single organism carbohydrate metabolic processGO:00447231180.013
endomembrane system organizationGO:0010256480.013
inorganic ion transmembrane transportGO:00986602290.013
blood circulationGO:00080151830.013
purine ribonucleoside catabolic processGO:00461301240.013
purine nucleoside catabolic processGO:00061521240.013
neuron deathGO:00709971270.013
response to insulinGO:00328681330.013
regulation of cellular component biogenesisGO:0044087860.013
gastrulationGO:000736920.013
regulation of protein serine threonine kinase activityGO:0071900640.013
positive regulation of catabolic processGO:0009896780.013
cellular cation homeostasisGO:00300031800.013
ensheathment of neuronsGO:0007272400.013
cell cell signalingGO:00072673350.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
regulation of cellular localizationGO:00603412630.013
male mating behaviorGO:006017930.013
heterocycle catabolic processGO:00467001670.013
positive regulation of cell proliferationGO:00082842490.013
positive regulation of mapk cascadeGO:0043410920.013
nucleoside triphosphate metabolic processGO:00091411440.013
sequestering of metal ionGO:005123890.013
positive regulation of hydrolase activityGO:0051345860.012
regulation of calcium ion transportGO:0051924770.012
synaptic transmissionGO:00072682350.012
insulin like growth factor receptor signaling pathwayGO:004800930.012
cellular response to peptide hormone stimulusGO:00713751200.012
positive regulation of rna metabolic processGO:00512542030.012
regulation of secretion by cellGO:19035302080.012
calcium ion homeostasisGO:00550741620.012
positive regulation of protein metabolic processGO:00512471780.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
response to interleukin 1GO:0070555550.012
axonogenesisGO:0007409710.012
sequestering of calcium ionGO:005120880.012
single organism catabolic processGO:00447122830.012
response to monosaccharideGO:00342841590.012
purine nucleoside metabolic processGO:00422781690.012
salivary gland developmentGO:000743130.012
organophosphate biosynthetic processGO:00904071430.012
guanosine containing compound metabolic processGO:1901068740.012
cognitionGO:0050890920.012
immune system processGO:00023762040.012
regulation of neuron deathGO:19012141150.012
ribonucleoside catabolic processGO:00424541260.012
response to hypoxiaGO:00016662310.011
gamete generationGO:00072761240.011
negative regulation of transportGO:00510511360.011
oxidation reduction processGO:00551143040.011
regulation of axonogenesisGO:0050770370.011
intracellular protein transportGO:0006886790.011
positive regulation of transferase activityGO:0051347810.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
negative regulation of neuron differentiationGO:0045665620.011
response to bacteriumGO:00096172000.011
reactive oxygen species biosynthetic processGO:190340980.011
gonad developmentGO:00084061040.011
response to decreased oxygen levelsGO:00362932370.011
negative regulation of developmental processGO:00510931250.011
lipid biosynthetic processGO:00086101280.011
negative regulation of neurogenesisGO:0050768780.011
response to glucoseGO:00097491360.011
cellular calcium ion homeostasisGO:00068741600.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
cellular response to peptideGO:19016531330.011
gtp catabolic processGO:0006184710.011
potassium ion transportGO:0006813970.011
negative regulation of cellular component organizationGO:0051129830.011
response to carbohydrateGO:00097431830.011
response to estrogenGO:00436272320.011
defense responseGO:00069521940.011
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.011
response to hexoseGO:00097461440.011
developmental process involved in reproductionGO:00030061590.010
vesicle mediated transportGO:00161921810.010
retina morphogenesis in camera type eyeGO:006004210.010
cellular nitrogen compound catabolic processGO:00442701630.010
lipid storageGO:001991510.010
cellular response to cytokine stimulusGO:00713451270.010
circulatory system developmentGO:00723591340.010
eye morphogenesisGO:004859240.010
response to glucocorticoidGO:00513842230.010
reactive oxygen species metabolic processGO:0072593370.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
response to ethanolGO:00454711620.010
glycerolipid metabolic processGO:0046486670.010
response to interleukin 15GO:007067240.010
negative regulation of neuron deathGO:1901215690.010
negative regulation of ion transportGO:0043271510.010
regulation of cellular response to stressGO:0080135490.010
male gamete generationGO:0048232990.010
regulation of transmembrane transportGO:00347621220.010
regulation of protein localizationGO:0032880810.010
negative regulation of rna metabolic processGO:00512531230.010
membrane depolarization during action potentialGO:008601010.010

Trim2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
central nervous system diseaseDOID:33100.023
brain diseaseDOID:93600.017
myopathyDOID:42300.012
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012
musculoskeletal system diseaseDOID:1700.012
disease of cellular proliferationDOID:1456600.011