Rattus norvegicus

19 known processes

Cflar

CASP8 and FADD-like apoptosis regulator

(Aliases: Flip,MGC108616)

Cflar biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein phosphorylationGO:00064683450.065
positive regulation of response to stimulusGO:00485842850.062
response to nutrient levelsGO:00316673700.060
carboxylic acid metabolic processGO:00197522890.059
regulation of molecular functionGO:00650093980.058
carbohydrate derivative metabolic processGO:19011353460.057
single organism biosynthetic processGO:00447113420.056
regulation of signal transductionGO:00099663180.056
cellular response to endogenous stimulusGO:00714953770.053
response to decreased oxygen levelsGO:00362932370.048
negative regulation of natural killer cell mediated immunityGO:000271640.047
response to extracellular stimulusGO:00099913800.047
regulation of rna biosynthetic processGO:20011413810.047
cellular amino acid metabolic processGO:00065201070.046
purine containing compound metabolic processGO:00725212530.045
regulation of phosphorus metabolic processGO:00511743490.045
nucleobase containing small molecule metabolic processGO:00550863160.044
response to biotic stimulusGO:00096072260.043
negative regulation of metabolic processGO:00098923310.042
organic acid metabolic processGO:00060822920.042
intracellular signal transductionGO:00355563140.041
regulation of protein metabolic processGO:00512462890.040
nucleoside phosphate metabolic processGO:00067532830.040
rna metabolic processGO:00160704060.039
response to oxidative stressGO:00069791860.039
cellular component assemblyGO:00226073600.038
positive regulation of signalingGO:00230562700.038
organophosphate metabolic processGO:00196373700.038
oxoacid metabolic processGO:00434362900.037
regulation of cellular ketone metabolic processGO:0010565270.037
amine metabolic processGO:0009308380.037
response to hypoxiaGO:00016662310.037
nucleic acid templated transcriptionGO:00976593790.037
regulation of cellular component organizationGO:00511283680.037
regulation of cellular protein metabolic processGO:00322682670.037
positive regulation of transcription factor import into nucleusGO:004299340.036
regulation of rna metabolic processGO:00512523910.036
cellular amine metabolic processGO:0044106380.035
multi organism reproductive processGO:00447032620.035
cellular response to cytokine stimulusGO:00713451270.035
response to oxygen levelsGO:00704822650.034
amino acid transportGO:0006865700.034
positive regulation of phosphate metabolic processGO:00459372620.034
response to acid chemicalGO:00011012220.034
positive regulation of molecular functionGO:00440932300.034
ribonucleotide metabolic processGO:00092592310.033
reproductive processGO:00224143720.033
homeostatic processGO:00425923310.033
response to peptide hormoneGO:00434342780.033
negative regulation of phosphorus metabolic processGO:0010563800.033
regulation of cellular amino acid metabolic processGO:000652120.033
transcription dna templatedGO:00063513770.033
regulation of catalytic activityGO:00507903040.031
regulation of intracellular signal transductionGO:19025312180.031
purine ribonucleotide metabolic processGO:00091502270.031
regulation of cellular amine metabolic processGO:003323880.031
negative regulation of innate immune responseGO:004582440.030
response to peptideGO:19016522920.030
organelle organizationGO:00069962660.030
negative regulation of cellular metabolic processGO:00313242810.030
response to bacteriumGO:00096172000.029
response to campGO:0051591910.029
nucleotide metabolic processGO:00091172790.029
regulation of protein phosphorylationGO:00019321830.029
regulation of nervous system developmentGO:00519602640.029
regulation of cell proliferationGO:00421273590.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
negative regulation of macromolecule metabolic processGO:00106052600.029
regulation of phosphorylationGO:00423252480.029
response to glucocorticoidGO:00513842230.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
catabolic processGO:00090563510.028
positive regulation of multicellular organismal processGO:00512403870.028
positive regulation of phosphorus metabolic processGO:00105622620.028
cellular catabolic processGO:00442482950.028
purine nucleotide metabolic processGO:00061632290.028
positive regulation of cellular biosynthetic processGO:00313282950.028
regulation of cell differentiationGO:00455953200.028
purine ribonucleoside metabolic processGO:00461281680.028
regulation of neurogenesisGO:00507672470.028
protein complex assemblyGO:00064612630.027
response to external biotic stimulusGO:00432072210.027
cellular response to stressGO:00335542690.027
protein complex biogenesisGO:00702712630.027
g protein coupled receptor signaling pathwayGO:00071862420.027
cellular response to nitrogen compoundGO:19016992100.027
negative regulation of nitrogen compound metabolic processGO:00511721610.027
response to other organismGO:00517072200.027
macromolecular complex assemblyGO:00650032730.027
locomotionGO:00400112370.026
cellular ketone metabolic processGO:0042180510.026
negative regulation of cellular biosynthetic processGO:00313271610.026
positive regulation of cell communicationGO:00106472710.026
regulation of phosphate metabolic processGO:00192203490.026
multicellular organismal reproductive processGO:00486092330.026
response to molecule of bacterial originGO:00022371940.026
response to carbohydrateGO:00097431830.026
single organism reproductive processGO:00447022970.026
negative regulation of response to stimulusGO:00485851550.025
ribonucleoside metabolic processGO:00091191740.025
positive regulation of cellular protein metabolic processGO:00322701670.025
regulation of transcription dna templatedGO:00063553740.025
purine nucleoside metabolic processGO:00422781690.025
chemical homeostasisGO:00488782920.025
anion transportGO:00068201780.024
organic substance catabolic processGO:19015753160.024
cellular chemical homeostasisGO:00550822470.024
regulation of hormone levelsGO:00108171870.024
regulation of protein modification processGO:00313991940.024
rna biosynthetic processGO:00327743800.024
positive regulation of biosynthetic processGO:00098913190.024
regulation of multicellular organismal developmentGO:20000263760.024
response to cytokineGO:00340972150.024
central nervous system developmentGO:00074173110.024
reproductionGO:00000032450.024
nucleoside metabolic processGO:00091161790.024
single organism catabolic processGO:00447122830.023
cellular component biogenesisGO:00440853680.023
alpha amino acid metabolic processGO:1901605710.023
regulation of cellular localizationGO:00603412630.023
immune system processGO:00023762040.023
positive regulation of developmental processGO:00510942830.023
cellular component movementGO:00069282480.022
regulation of immunoglobulin secretionGO:005102310.022
organic acid transportGO:00158491160.022
peptidyl amino acid modificationGO:00181931260.022
response to radiationGO:00093141370.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.022
response to lipopolysaccharideGO:00324961910.022
neuron developmentGO:00486662860.022
transcription from rna polymerase ii promoterGO:00063662520.022
regulation of nucleotide metabolic processGO:00061401170.022
cellular response to organonitrogen compoundGO:00714171970.022
negative regulation of biosynthetic processGO:00098901680.022
organonitrogen compound catabolic processGO:19015651790.022
cation transportGO:00068123820.021
positive regulation of nervous system developmentGO:00519621780.021
metal ion transportGO:00300012890.021
positive regulation of protein metabolic processGO:00512471780.021
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.021
cellular ion homeostasisGO:00068731840.021
negative regulation of gene expressionGO:00106291990.021
response to mechanical stimulusGO:00096121340.021
positive regulation of cellular amine metabolic processGO:003324030.021
regulation of neuron deathGO:19012141150.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
neurological system processGO:00508772190.021
positive regulation of cell deathGO:00109421840.020
ribose phosphate metabolic processGO:00196932350.020
positive regulation of transportGO:00510502450.020
response to purine containing compoundGO:00140741260.020
organonitrogen compound biosynthetic processGO:19015661670.020
negative regulation of molecular functionGO:00440921330.020
response to organophosphorusGO:00466831020.019
ribonucleotide catabolic processGO:00092611360.019
regulation of apoptotic processGO:00429813350.019
action potentialGO:0001508540.019
apoptotic processGO:00069153810.019
cell projection organizationGO:00300303020.019
cytosolic calcium ion homeostasisGO:00514801400.019
ion homeostasisGO:00508012120.019
regulation of protein kinase activityGO:00458591050.019
regulation of homeostatic processGO:00328441010.019
macromolecule localizationGO:00330362520.019
organic anion transportGO:00157111320.019
response to hydrogen peroxideGO:0042542890.019
negative regulation of cell differentiationGO:0045596990.019
programmed cell deathGO:00125013920.018
cell cell signalingGO:00072673350.018
positive regulation of signal transductionGO:00099671750.018
rhythmic processGO:00485111560.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
ras protein signal transductionGO:0007265290.018
intracellular transportGO:00469071850.018
regulation of secretion by cellGO:19035302080.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
growthGO:00400071650.018
multicellular organism reproductionGO:00325042330.018
transmembrane transportGO:00550854120.018
regulation of catabolic processGO:00098941130.018
cellular response to oxygen containing compoundGO:19017013860.018
synaptic transmissionGO:00072682350.018
response to insulinGO:00328681330.018
negative regulation of multicellular organismal processGO:00512412030.018
negative regulation of signalingGO:00230571570.018
positive regulation of cellular component organizationGO:00511302000.018
regulation of purine nucleotide metabolic processGO:19005421150.018
response to reactive oxygen speciesGO:00003021200.018
positive regulation of cell proliferationGO:00082842490.018
protein complex subunit organizationGO:00718223020.018
heterocycle catabolic processGO:00467001670.018
response to ethanolGO:00454711620.017
gland developmentGO:00487321550.017
response to monosaccharideGO:00342841590.017
cellular homeostasisGO:00197252520.017
protein oligomerizationGO:00512591910.017
metal ion homeostasisGO:00550651860.017
dephosphorylationGO:0016311980.017
b cell mediated immunityGO:001972440.017
purine containing compound catabolic processGO:00725231380.017
calcium ion transportGO:00068161310.017
regulation of cell developmentGO:00602842630.017
regulation of cellular catabolic processGO:00313291010.017
regulation of ion transportGO:00432692450.016
nucleotide catabolic processGO:00091661390.016
reactive oxygen species metabolic processGO:0072593370.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
cellular nitrogen compound catabolic processGO:00442701630.016
organic cyclic compound catabolic processGO:19013611750.016
brain developmentGO:00074202470.016
positive regulation of intracellular signal transductionGO:19025331380.016
nitrogen compound transportGO:00717052290.016
reproductive system developmentGO:00614581280.016
single organism organelle organizationGO:19025891800.016
cellular cation homeostasisGO:00300031800.015
sexual reproductionGO:00199531480.015
vesicle mediated transportGO:00161921810.015
regulation of hydrolase activityGO:00513361430.015
glycosyl compound metabolic processGO:19016571820.015
coenzyme metabolic processGO:0006732860.015
positive regulation of rna metabolic processGO:00512542030.015
sensory perceptionGO:00076001010.015
nucleoside triphosphate metabolic processGO:00091411440.015
regulation of programmed cell deathGO:00430673410.015
regulation of response to stressGO:00801341260.015
ribonucleoside catabolic processGO:00424541260.015
single organism intracellular transportGO:19025821660.015
response to corticosteroidGO:00319602350.015
cation homeostasisGO:00550801950.015
purine ribonucleoside catabolic processGO:00461301240.015
gastrulationGO:000736920.015
neuron differentiationGO:00301823680.015
positive regulation of gene expressionGO:00106282440.015
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
neuron projection developmentGO:00311752730.015
leukocyte differentiationGO:0002521300.015
organophosphate catabolic processGO:00464341480.014
response to starvationGO:0042594590.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
amine transportGO:0015837570.014
response to ketoneGO:19016541820.014
jak stat cascadeGO:0007259260.014
tumor necrosis factor mediated signaling pathwayGO:003320940.014
response to glucoseGO:00097491360.014
negative regulation of cell communicationGO:00106481580.014
cellular protein localizationGO:00346131220.014
response to hexoseGO:00097461440.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
secretionGO:00469033070.014
response to alkaloidGO:00432791320.014
divalent inorganic cation transportGO:00725111340.014
chromosome segregationGO:000705920.014
positive regulation of phosphorylationGO:00423271770.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
positive regulation of immune system processGO:0002684900.014
salivary gland morphogenesisGO:000743510.014
circulatory system processGO:00030131830.014
cell motilityGO:00488702020.014
peptidyl tyrosine modificationGO:0018212720.014
response to inorganic substanceGO:00100353770.014
circadian rhythmGO:0007623880.014
protein localizationGO:00081041910.014
cell migrationGO:00164771970.014
ribonucleoside triphosphate metabolic processGO:00091991410.013
cellular response to tumor necrosis factorGO:0071356460.013
purine nucleotide catabolic processGO:00061951360.013
negative regulation of cell deathGO:00605482290.013
positive regulation of cell developmentGO:00107201760.013
positive regulation of protein modification processGO:00314011420.013
guanosine containing compound catabolic processGO:1901069710.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
regulation of organelle organizationGO:0033043800.013
calcium ion homeostasisGO:00550741620.013
negative regulation of transportGO:00510511360.013
carbohydrate derivative catabolic processGO:19011361470.013
regulation of immune system processGO:00026821230.013
nucleoside catabolic processGO:00091641260.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
nucleoside triphosphate catabolic processGO:00091431230.013
negative regulation of catalytic activityGO:00430861030.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
proteolysisGO:00065081750.013
peptidyl tyrosine phosphorylationGO:0018108720.013
positive regulation of apoptotic processGO:00430651540.013
regenerationGO:00310991630.013
carboxylic acid transportGO:00469421150.013
reactive nitrogen species metabolic processGO:200105710.013
positive regulation of cell differentiationGO:00455972170.013
salivary gland developmentGO:000743130.013
aromatic compound catabolic processGO:00194391680.012
spindle organizationGO:000705120.012
inflammatory responseGO:00069541500.012
nucleoside phosphate biosynthetic processGO:19012931020.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
guanosine containing compound metabolic processGO:1901068740.012
purine nucleoside catabolic processGO:00061521240.012
cell activationGO:0001775970.012
macromolecular complex subunit organizationGO:00439333390.012
gliogenesisGO:0042063930.012
positive regulation of programmed cell deathGO:00430681570.012
carbohydrate metabolic processGO:00059751300.012
chemosensory behaviorGO:000763520.012
axis specificationGO:000979840.012
secretion by cellGO:00329402480.012
cellular response to insulin stimulusGO:0032869810.012
negative regulation of protein metabolic processGO:00512481140.012
retinal metabolic processGO:004257430.012
response to nutrientGO:00075842480.012
reactive oxygen species biosynthetic processGO:190340980.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
immune responseGO:00069551040.012
ion transmembrane transportGO:00342203650.012
cellular response to hormone stimulusGO:00328702470.012
small molecule biosynthetic processGO:00442831240.012
negative regulation of phosphate metabolic processGO:0045936800.012
negative regulation of cellular component organizationGO:0051129830.012
regulation of cell projection organizationGO:00313441750.012
response to estrogenGO:00436272320.012
neuron deathGO:00709971270.012
gtp metabolic processGO:0046039720.012
cell cycle checkpointGO:000007520.012
carbohydrate derivative biosynthetic processGO:19011371240.012
regulation of interferon gamma productionGO:003264930.012
cofactor metabolic processGO:0051186950.012
monosaccharide metabolic processGO:0005996610.011
response to activityGO:0014823730.011
gamete generationGO:00072761240.011
synaptic growth at neuromuscular junctionGO:005112410.011
regulation of neuron projection developmentGO:00109751610.011
establishment of protein localizationGO:00451841410.011
muscle system processGO:00030121150.011
regulation of growthGO:00400081050.011
regulation of proteasomal protein catabolic processGO:006113640.011
cellular calcium ion homeostasisGO:00068741600.011
innate immune responseGO:0045087350.011
response to estradiolGO:00323551640.011
cellular response to peptideGO:19016531330.011
response to growth factorGO:00708481890.011
macromolecule catabolic processGO:0009057580.011
nucleoside phosphate catabolic processGO:19012921400.011
nucleotide biosynthetic processGO:0009165980.011
lipid biosynthetic processGO:00086101280.011
regulation of transferase activityGO:00513381230.011
cellular response to growth factor stimulusGO:00713631620.011
glial cell differentiationGO:0010001650.011
multi multicellular organism processGO:00447061380.011
single organism carbohydrate metabolic processGO:00447231180.011
circulatory system developmentGO:00723591340.011
response to woundingGO:00096112540.011
positive regulation of nf kappab import into nucleusGO:004234620.011
response to transition metal nanoparticleGO:19902671220.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
lymphocyte activationGO:0046649430.011
behaviorGO:00076102050.011
organophosphate biosynthetic processGO:00904071430.011
regulation of gtpase activityGO:0043087570.011
lipid metabolic processGO:00066292830.011
sex differentiationGO:00075481130.011
cellular macromolecule localizationGO:00707271220.011
alpha amino acid biosynthetic processGO:1901607230.011
negative regulation of transcription dna templatedGO:00458921160.011
carboxylic acid biosynthetic processGO:0046394830.011
single organism cellular localizationGO:19025801020.011
female pregnancyGO:00075651220.011
regulation of peptide transportGO:0090087870.011
response to amineGO:0014075460.011
positive regulation of rna biosynthetic processGO:19026801970.011
negative regulation of cellular protein metabolic processGO:00322691060.011
mapk cascadeGO:00001651400.011
organ regenerationGO:00311001010.011
cell cycleGO:00070491010.011
regulation of secretionGO:00510462240.011
negative regulation of phosphorylationGO:0042326570.011
regulation of synaptic transmissionGO:00508041410.011
olfactory behaviorGO:004204820.011
intracellular protein transportGO:0006886790.010
immunoglobulin secretionGO:004830510.010
activation of cysteine type endopeptidase activityGO:009720240.010
positive regulation of nucleotide metabolic processGO:0045981910.010
leukocyte activationGO:0045321760.010
peptide transportGO:0015833970.010
cellular metal ion homeostasisGO:00068751720.010
cyclic purine nucleotide metabolic processGO:0052652620.010
purine ribonucleotide catabolic processGO:00091541360.010
purine containing compound biosynthetic processGO:0072522850.010
cytoplasmic transportGO:00164821150.010
cell type specific apoptotic processGO:00972851340.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
cellular response to abiotic stimulusGO:0071214850.010
hexose metabolic processGO:0019318580.010
regulation of nucleoside metabolic processGO:0009118660.010
protein heterooligomerizationGO:0051291890.010
glycosyl compound catabolic processGO:19016581260.010
gtp catabolic processGO:0006184710.010
negative regulation of signal transductionGO:0009968830.010
cellular response to external stimulusGO:00714961180.010

Cflar disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
inherited metabolic disorderDOID:65500.019
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.013
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
central nervous system diseaseDOID:33100.010