Rattus norvegicus

0 known processes

Akr1b8

aldo-keto reductase family 1, member B8

(Aliases: MGC91427)

Akr1b8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism catabolic processGO:00447122830.264
Human
apoptotic processGO:00069153810.220
regulation of programmed cell deathGO:00430673410.219
response to inorganic substanceGO:00100353770.194
Rat
regulation of cell proliferationGO:00421273590.180
Rat
regulation of apoptotic processGO:00429813350.179
programmed cell deathGO:00125013920.166
response to oxidative stressGO:00069791860.164
Rat
organic acid biosynthetic processGO:0016053830.156
response to extracellular stimulusGO:00099913800.152
response to reactive oxygen speciesGO:00003021200.147
Rat
response to metal ionGO:00100382530.144
cellular response to organic cyclic compoundGO:00714072020.142
oxoacid metabolic processGO:00434362900.116
glutathione metabolic processGO:0006749150.110
response to woundingGO:00096112540.108
response to estrogenGO:00436272320.100
Rat
response to nutrient levelsGO:00316673700.094
cellular response to reactive oxygen speciesGO:0034614550.094
Rat
oxidation reduction processGO:00551143040.092
Human Rat
regulation of nucleic acid templated transcriptionGO:19035063800.089
response to hydrogen peroxideGO:0042542890.086
Rat
carboxylic acid biosynthetic processGO:0046394830.084
organic acid metabolic processGO:00060822920.083
carboxylic acid metabolic processGO:00197522890.080
response to nutrientGO:00075842480.079
cell type specific apoptotic processGO:00972851340.079
tissue developmentGO:00098882520.077
regenerationGO:00310991630.077
cellular response to oxygen containing compoundGO:19017013860.072
Rat
negative regulation of cell proliferationGO:00082851190.072
transcription dna templatedGO:00063513770.070
cellular response to stressGO:00335542690.068
Rat
negative regulation of cell deathGO:00605482290.068
response to ethanolGO:00454711620.067
positive regulation of cellular biosynthetic processGO:00313282950.067
catabolic processGO:00090563510.064
Human
response to peptideGO:19016522920.064
Rat
negative regulation of metabolic processGO:00098923310.064
cellular response to steroid hormone stimulusGO:0071383930.060
response to glucocorticoidGO:00513842230.060
positive regulation of cell deathGO:00109421840.059
cellular amino acid metabolic processGO:00065201070.059
lipid metabolic processGO:00066292830.058
Human Rat
single organism biosynthetic processGO:00447113420.056
Rat
single organism reproductive processGO:00447022970.055
Rat
ion transmembrane transportGO:00342203650.055
cation transportGO:00068123820.055
cellular response to oxidative stressGO:0034599760.052
Rat
cellular ketone metabolic processGO:0042180510.052
Human
cellular lipid metabolic processGO:00442552080.051
Human Rat
cellular amino acid biosynthetic processGO:0008652320.050
negative regulation of programmed cell deathGO:00430691830.049
small molecule biosynthetic processGO:00442831240.049
Rat
positive regulation of programmed cell deathGO:00430681570.049
response to hypoxiaGO:00016662310.049
positive regulation of biosynthetic processGO:00098913190.049
neuron apoptotic processGO:0051402880.048
blood circulationGO:00080151830.048
rna metabolic processGO:00160704060.047
negative regulation of biosynthetic processGO:00098901680.047
positive regulation of apoptotic processGO:00430651540.047
cell cell signalingGO:00072673350.047
nucleic acid templated transcriptionGO:00976593790.046
nonribosomal peptide biosynthetic processGO:001918430.045
response to estradiolGO:00323551640.045
regulation of transcription dna templatedGO:00063553740.045
cellular catabolic processGO:00442482950.044
Human
negative regulation of response to stimulusGO:00485851550.044
negative regulation of cellular biosynthetic processGO:00313271610.042
transmembrane transportGO:00550854120.042
divalent inorganic cation transportGO:00725111340.041
nucleotide metabolic processGO:00091172790.041
negative regulation of apoptotic processGO:00430661810.040
response to growth factorGO:00708481890.040
regulation of response to stressGO:00801341260.040
cellular amine metabolic processGO:0044106380.039
response to hexoseGO:00097461440.037
multicellular organism reproductionGO:00325042330.037
Rat
sulfur compound metabolic processGO:0006790700.037
rna biosynthetic processGO:00327743800.037
negative regulation of cytokine productionGO:0001818160.036
response to toxic substanceGO:00096361330.036
response to transition metal nanoparticleGO:19902671220.036
regulation of rna metabolic processGO:00512523910.036
anatomical structure morphogenesisGO:00096532980.035
regulation of molecular functionGO:00650093980.035
organophosphate metabolic processGO:00196373700.035
response to monosaccharideGO:00342841590.034
cellular response to glucocorticoid stimulusGO:0071385680.034
cytokine productionGO:0001816610.033
cellular response to extracellular stimulusGO:0031668730.033
response to oxygen levelsGO:00704822650.033
reactive oxygen species metabolic processGO:0072593370.033
regulation of rna biosynthetic processGO:20011413810.033
cellular response to lipidGO:00713962010.032
localization of cellGO:00516742020.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
negative regulation of gene expressionGO:00106291990.031
cellular response to corticosteroid stimulusGO:0071384690.031
monocarboxylic acid metabolic processGO:00327871520.031
protein homooligomerizationGO:0051260910.031
divalent metal ion transportGO:00708381320.030
negative regulation of multicellular organismal processGO:00512412030.030
protein oligomerizationGO:00512591910.030
response to peptide hormoneGO:00434342780.030
cell projection organizationGO:00300303020.029
urogenital system developmentGO:0001655780.029
Rat
response to amino acidGO:0043200750.029
regulation of neuron apoptotic processGO:0043523830.029
homeostatic processGO:00425923310.029
Rat
response to decreased oxygen levelsGO:00362932370.029
central nervous system developmentGO:00074173110.028
Rat Fly
response to vitaminGO:00332731310.028
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.028
response to corticosteroidGO:00319602350.028
multi multicellular organism processGO:00447061380.027
Rat
reproductive system developmentGO:00614581280.027
protein complex assemblyGO:00064612630.027
organic substance catabolic processGO:19015753160.027
Human
cellular response to endogenous stimulusGO:00714953770.027
Rat
nucleobase containing small molecule metabolic processGO:00550863160.027
response to carbohydrateGO:00097431830.026
negative regulation of transportGO:00510511360.026
cellular component biogenesisGO:00440853680.026
positive regulation of developmental processGO:00510942830.026
brain developmentGO:00074202470.026
Rat Fly
cellular component assemblyGO:00226073600.026
single organism carbohydrate metabolic processGO:00447231180.025
Rat
circulatory system processGO:00030131830.025
cell motilityGO:00488702020.025
regulation of cellular amino acid metabolic processGO:000652120.025
regulation of cellular ketone metabolic processGO:0010565270.025
regulation of ion transmembrane transportGO:00347651210.025
regulation of neuron deathGO:19012141150.024
female pregnancyGO:00075651220.024
Rat
regulation of phosphorus metabolic processGO:00511743490.024
response to glucoseGO:00097491360.024
response to zinc ionGO:0010043390.024
negative regulation of cellular metabolic processGO:00313242810.024
regulation of response to external stimulusGO:00321011060.024
immune system processGO:00023762040.024
positive regulation of rna biosynthetic processGO:19026801970.024
positive regulation of voltage gated calcium channel activityGO:190138710.024
growthGO:00400071650.024
regulation of catalytic activityGO:00507903040.023
single organism cellular localizationGO:19025801020.023
metal ion transportGO:00300012890.023
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.023
regulation of blood pressureGO:0008217830.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
cellular modified amino acid metabolic processGO:0006575610.023
positive regulation of protein modification processGO:00314011420.022
carbohydrate derivative metabolic processGO:19011353460.022
Human
wound healingGO:00420601220.022
response to alkaloidGO:00432791320.022
cellular response to hypoxiaGO:0071456510.022
cellular response to growth factor stimulusGO:00713631620.022
organonitrogen compound biosynthetic processGO:19015661670.022
macromolecular complex subunit organizationGO:00439333390.022
cellular response to alcoholGO:0097306870.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
organic anion transportGO:00157111320.021
reproductive structure developmentGO:00486081280.021
leukocyte proliferationGO:0070661290.021
negative regulation of cell communicationGO:00106481580.021
regulation of cytokine productionGO:0001817560.021
intracellular signal transductionGO:00355563140.021
Rat
secretionGO:00469033070.021
purine ribonucleoside monophosphate catabolic processGO:0009169550.021
regulation of defense responseGO:0031347680.021
regulation of leukocyte activationGO:0002694450.021
cellular response to hormone stimulusGO:00328702470.020
regulation of cellular localizationGO:00603412630.020
organonitrogen compound catabolic processGO:19015651790.020
cell activationGO:0001775970.020
single organism intracellular transportGO:19025821660.020
response to acid chemicalGO:00011012220.020
Rat
amine metabolic processGO:0009308380.020
developmental process involved in reproductionGO:00030061590.020
ossificationGO:0001503700.020
regulation of nervous system developmentGO:00519602640.020
regulation of ion transportGO:00432692450.020
calcium ion importGO:0070509220.020
regulation of calcium ion transportGO:0051924770.020
regulation of multicellular organismal developmentGO:20000263760.020
unsaturated fatty acid metabolic processGO:0033559390.020
cation transmembrane transportGO:00986552630.020
negative regulation of secretionGO:0051048820.020
positive regulation of gene expressionGO:00106282440.019
response to bacteriumGO:00096172000.019
negative regulation of nucleobase containing compound metabolic processGO:00459341530.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
regulation of anatomical structure morphogenesisGO:00226031410.019
organic cyclic compound catabolic processGO:19013611750.019
negative regulation of macromolecule metabolic processGO:00106052600.019
cellular response to nutrient levelsGO:0031669600.019
inorganic cation transmembrane transportGO:00986622020.018
vascular process in circulatory systemGO:0003018960.018
calcium ion transportGO:00068161310.018
t cell extravasationGO:007268310.018
cellular homeostasisGO:00197252520.018
rhythmic processGO:00485111560.018
eosinophil migrationGO:007267730.017
lipid biosynthetic processGO:00086101280.017
regulation of skeletal muscle cell differentiationGO:200101410.017
negative regulation of molecular functionGO:00440921330.017
positive regulation of transcription dna templatedGO:00458931970.017
regulation of transmembrane transportGO:00347621220.017
cd8 positive alpha beta t cell extravasationGO:003569700.017
regulation of cellular amine metabolic processGO:003323880.017
organophosphate biosynthetic processGO:00904071430.017
regulation of protein modification processGO:00313991940.017
nitrogen compound transportGO:00717052290.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
response to purine containing compoundGO:00140741260.017
nucleoside phosphate metabolic processGO:00067532830.017
inorganic ion transmembrane transportGO:00986602290.017
positive regulation of cellular amine metabolic processGO:003324030.017
secretion by cellGO:00329402480.016
cellular component movementGO:00069282480.016
organ regenerationGO:00311001010.016
biological adhesionGO:00226101100.016
regulation of tube sizeGO:0035150890.016
synaptic transmissionGO:00072682350.016
locomotionGO:00400112370.016
reproductive processGO:00224143720.016
Rat
response to cytokineGO:00340972150.016
protein complex subunit organizationGO:00718223020.016
regulation of system processGO:00440572080.016
negative regulation of protein metabolic processGO:00512481140.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
hexose metabolic processGO:0019318580.016
regulation of protein phosphorylationGO:00019321830.016
regulation of phosphate metabolic processGO:00192203490.016
regulation of anatomical structure sizeGO:00900661350.015
acute inflammatory responseGO:0002526580.015
cellular response to metal ionGO:0071248550.015
pyridine containing compound metabolic processGO:0072524320.015
glycosyl compound metabolic processGO:19016571820.015
Human
maternal process involved in female pregnancyGO:0060135380.015
Rat
aromatic compound catabolic processGO:00194391680.015
cellular nitrogen compound catabolic processGO:00442701630.015
carbohydrate homeostasisGO:0033500750.015
response to ketoneGO:19016541820.015
Rat
head developmentGO:00603222470.015
Rat Fly
multicellular organismal reproductive processGO:00486092330.015
Rat
fatty acid metabolic processGO:0006631990.015
regulation of vasculature developmentGO:1901342440.015
regulation of phosphorylationGO:00423252480.015
neuron deathGO:00709971270.015
negative regulation of signalingGO:00230571570.015
hepaticobiliary system developmentGO:0061008900.015
positive regulation of molecular functionGO:00440932300.015
purine containing compound catabolic processGO:00725231380.015
regulation of cell activationGO:0050865500.014
purine nucleotide metabolic processGO:00061632290.014
negative regulation of transcription dna templatedGO:00458921160.014
positive regulation of rna metabolic processGO:00512542030.014
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.014
neuron differentiationGO:00301823680.014
protein complex biogenesisGO:00702712630.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
anion transportGO:00068201780.014
regulation of cellular component organizationGO:00511283680.014
regulation of neurogenesisGO:00507672470.014
inflammatory responseGO:00069541500.014
positive regulation of transmembrane transportGO:0034764250.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
agingGO:00075682410.014
macromolecular complex assemblyGO:00650032730.014
development of primary sexual characteristicsGO:00451371070.014
sex differentiationGO:00075481130.013
monocarboxylic acid biosynthetic processGO:0072330480.013
cellular response to peptideGO:19016531330.013
Rat
ovulation cycle processGO:0022602500.013
negative regulation of rna biosynthetic processGO:19026791180.013
regulation of protein maturationGO:1903317500.013
cellular modified amino acid biosynthetic processGO:0042398180.013
negative regulation of secretion by cellGO:1903531720.013
gland developmentGO:00487321550.013
intracellular transportGO:00469071850.013
ribose phosphate biosynthetic processGO:0046390870.013
response to other organismGO:00517072200.013
cellular response to oxygen levelsGO:0071453600.013
small gtpase mediated signal transductionGO:0007264360.013
regulation of kinase activityGO:00435491170.013
cell adhesionGO:00071551100.013
negative regulation of rna metabolic processGO:00512531230.013
neuronal action potentialGO:0019228350.013
cellular response to molecule of bacterial originGO:0071219560.013
response to insulinGO:00328681330.013
ribonucleoside monophosphate metabolic processGO:0009161880.013
reproductionGO:00000032450.012
Rat
protein phosphorylationGO:00064683450.012
calcium ion transmembrane transportGO:0070588700.012
forebrain developmentGO:0030900980.012
Rat
multi organism reproductive processGO:00447032620.012
Rat
cellular response to abiotic stimulusGO:0071214850.012
positive regulation of lipid catabolic processGO:005099640.012
peptide metabolic processGO:0006518320.012
protein maturationGO:0051604680.012
chemical homeostasisGO:00488782920.012
neuron projection developmentGO:00311752730.012
mononuclear cell migrationGO:007167430.012
fatty acid derivative metabolic processGO:1901568380.012
cell migrationGO:00164771970.012
regulation of secretion by cellGO:19035302080.012
cell growthGO:00160491040.012
positive regulation of defense responseGO:0031349370.012
ribonucleotide metabolic processGO:00092592310.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
heterocycle catabolic processGO:00467001670.012
response to molecule of bacterial originGO:00022371940.012
cardiovascular system developmentGO:00723581340.012
erythrocyte differentiationGO:003021810.012
cellular response to inorganic substanceGO:0071241650.012
macromolecule localizationGO:00330362520.012
response to external biotic stimulusGO:00432072210.012
glutathione biosynthetic processGO:000675030.012
purine ribonucleotide catabolic processGO:00091541360.012
cellular response to external stimulusGO:00714961180.012
carboxylic acid transportGO:00469421150.012
multicellular organism growthGO:003526410.012
positive regulation of inflammatory responseGO:0050729240.012
cellular amide metabolic processGO:0043603440.012
regulation of cellular component biogenesisGO:0044087860.012
cellular component morphogenesisGO:00329891550.011
response to activityGO:0014823730.011
gonad developmentGO:00084061040.011
signal transduction by phosphorylationGO:00230141440.011
transcription from rna polymerase ii promoterGO:00063662520.011
regulation of cell developmentGO:00602842630.011
positive regulation of transportGO:00510502450.011
cellular protein localizationGO:00346131220.011
regulation of blood circulationGO:19035221100.011
developmental growthGO:00485891000.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
cellular response to ketoneGO:1901655510.011
Rat
regulation of response to woundingGO:1903034690.011
regulation of endothelial cell apoptotic processGO:200035130.011
circulatory system developmentGO:00723591340.011
signal releaseGO:00230611450.011
nicotinamide nucleotide metabolic processGO:0046496280.011
response to lipopolysaccharideGO:00324961910.011
purine ribonucleoside catabolic processGO:00461301240.011
regulation of cell motilityGO:20001451310.011
defense responseGO:00069521940.011
purine ribonucleoside metabolic processGO:00461281680.011
cellular response to fluid shear stressGO:007149840.011
carbohydrate derivative catabolic processGO:19011361470.011
cellular response to nutrientGO:0031670300.011
icosanoid metabolic processGO:0006690380.011
skeletal muscle cell differentiationGO:003591420.011
ribose phosphate metabolic processGO:00196932350.011
negative regulation of response to external stimulusGO:0032102370.011
glucose homeostasisGO:0042593750.011
positive regulation of signalingGO:00230562700.011
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
regulation of protein localizationGO:0032880810.010
regulation of cellular component sizeGO:0032535510.010
regulation of cell morphogenesisGO:0022604770.010
icosanoid biosynthetic processGO:0046456180.010
response to nicotineGO:0035094510.010
negative regulation of signal transductionGO:0009968830.010
macrophage chemotaxisGO:004824620.010
regulation of vesicle mediated transportGO:0060627810.010
regulation of cell projection organizationGO:00313441750.010
regulation of synaptic plasticityGO:0048167700.010
synaptic growth at neuromuscular junctionGO:005112410.010
negative regulation of neuron deathGO:1901215690.010
organic acid transportGO:00158491160.010
positive regulation of protein metabolic processGO:00512471780.010

Akr1b8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.027
central nervous system diseaseDOID:33100.015