Rattus norvegicus

10 known processes

Enpep

glutamyl aminopeptidase

Enpep biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.274
cellular response to endogenous stimulusGO:00714953770.237
cellular response to organonitrogen compoundGO:00714171970.207
cellular response to hormone stimulusGO:00328702470.180
regulation of programmed cell deathGO:00430673410.179
cation transportGO:00068123820.175
programmed cell deathGO:00125013920.158
cellular response to peptide hormone stimulusGO:00713751200.155
cellular amino acid metabolic processGO:00065201070.151
protein phosphorylationGO:00064683450.137
transcription dna templatedGO:00063513770.134
organic acid metabolic processGO:00060822920.123
response to extracellular stimulusGO:00099913800.122
regulation of cell proliferationGO:00421273590.120
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.119
transcription from rna polymerase ii promoterGO:00063662520.118
response to peptide hormoneGO:00434342780.112
regulation of apoptotic processGO:00429813350.109
inorganic ion transmembrane transportGO:00986602290.108
carboxylic acid metabolic processGO:00197522890.106
cellular response to oxygen containing compoundGO:19017013860.104
cellular response to nitrogen compoundGO:19016992100.101
transmembrane transportGO:00550854120.098
response to nutrient levelsGO:00316673700.096
nitrogen compound transportGO:00717052290.093
cellular response to peptideGO:19016531330.092
secretionGO:00469033070.088
carbohydrate derivative metabolic processGO:19011353460.086
regulation of cellular protein metabolic processGO:00322682670.084
regulation of molecular functionGO:00650093980.084
cell cell signalingGO:00072673350.082
nucleic acid templated transcriptionGO:00976593790.081
positive regulation of cellular biosynthetic processGO:00313282950.080
response to corticosteroidGO:00319602350.078
organophosphate metabolic processGO:00196373700.078
cellular amine metabolic processGO:0044106380.078
negative regulation of cellular metabolic processGO:00313242810.078
immune system processGO:00023762040.075
regulation of cell differentiationGO:00455953200.075
negative regulation of gene expressionGO:00106291990.073
cellular response to insulin stimulusGO:0032869810.072
apoptotic processGO:00069153810.071
regenerationGO:00310991630.071
cation transmembrane transportGO:00986552630.071
ion transmembrane transportGO:00342203650.071
nucleobase containing small molecule metabolic processGO:00550863160.070
regulation of system processGO:00440572080.070
positive regulation of cell communicationGO:00106472710.068
homeostatic processGO:00425923310.067
negative regulation of metabolic processGO:00098923310.067
inorganic cation transmembrane transportGO:00986622020.066
regulation of catalytic activityGO:00507903040.065
regulation of phosphorus metabolic processGO:00511743490.065
regulation of cellular ketone metabolic processGO:0010565270.065
amine metabolic processGO:0009308380.065
positive regulation of nitrogen compound metabolic processGO:00511733340.065
response to peptideGO:19016522920.064
response to insulinGO:00328681330.063
locomotionGO:00400112370.063
enzyme linked receptor protein signaling pathwayGO:00071671160.062
protein autophosphorylationGO:0046777660.062
response to growth factorGO:00708481890.062
cellular response to corticosteroid stimulusGO:0071384690.060
positive regulation of developmental processGO:00510942830.060
cellular ketone metabolic processGO:0042180510.060
regulation of rna metabolic processGO:00512523910.059
regulation of transcription from rna polymerase ii promoterGO:00063572340.059
response to acid chemicalGO:00011012220.059
positive regulation of signal transductionGO:00099671750.058
retinoic acid receptor signaling pathwayGO:004838470.058
regulation of transcription dna templatedGO:00063553740.057
single organism biosynthetic processGO:00447113420.057
peptidyl amino acid modificationGO:00181931260.056
regulation of cellular amino acid metabolic processGO:000652120.056
protein complex biogenesisGO:00702712630.056
head developmentGO:00603222470.056
positive regulation of immune system processGO:0002684900.055
regulation of phosphate metabolic processGO:00192203490.055
macromolecule localizationGO:00330362520.054
blood vessel morphogenesisGO:0048514580.054
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.054
response to carbohydrateGO:00097431830.054
positive regulation of multicellular organismal processGO:00512403870.053
muscle cell proliferationGO:0033002840.053
negative regulation of cell deathGO:00605482290.053
negative regulation of nitrogen compound metabolic processGO:00511721610.053
negative regulation of cell proliferationGO:00082851190.053
regulation of signal transductionGO:00099663180.052
neurological system processGO:00508772190.052
hormone transportGO:00099141210.052
vesicle mediated transportGO:00161921810.052
response to glucoseGO:00097491360.052
smooth muscle cell proliferationGO:0048659770.051
regulation of hormone levelsGO:00108171870.051
anatomical structure morphogenesisGO:00096532980.050
regulation of multicellular organismal developmentGO:20000263760.050
positive regulation of response to stimulusGO:00485842850.050
organic anion transportGO:00157111320.050
cellular response to organic cyclic compoundGO:00714072020.049
response to glucocorticoidGO:00513842230.049
anatomical structure formation involved in morphogenesisGO:0048646830.049
cellular response to lipidGO:00713962010.048
response to ethanolGO:00454711620.048
alpha amino acid metabolic processGO:1901605710.047
cellular component assemblyGO:00226073600.047
response to oxygen levelsGO:00704822650.047
positive regulation of biosynthetic processGO:00098913190.047
regulation of cellular component organizationGO:00511283680.047
response to inorganic substanceGO:00100353770.047
positive regulation of nucleobase containing compound metabolic processGO:00459353190.047
macromolecular complex subunit organizationGO:00439333390.046
response to nutrientGO:00075842480.046
cellular response to growth factor stimulusGO:00713631620.046
response to lipopolysaccharideGO:00324961910.046
regulation of nervous system developmentGO:00519602640.046
regulation of mesenchymal cell proliferationGO:001046440.045
regulation of cellular amine metabolic processGO:003323880.045
ion homeostasisGO:00508012120.045
blood circulationGO:00080151830.045
cellular component biogenesisGO:00440853680.044
metal ion transportGO:00300012890.044
positive regulation of catalytic activityGO:00430851840.044
positive regulation of transcription dna templatedGO:00458931970.044
organ formationGO:004864530.043
cell projection organizationGO:00300303020.043
response to decreased oxygen levelsGO:00362932370.043
cardiovascular system developmentGO:00723581340.043
response to cytokineGO:00340972150.042
positive regulation of neurogenesisGO:00507691650.042
endochondral bone growthGO:000341630.042
positive regulation of protein metabolic processGO:00512471780.042
regulation of secretionGO:00510462240.042
anterior posterior pattern specificationGO:000995210.042
regulation of protein modification processGO:00313991940.042
organic substance catabolic processGO:19015753160.041
protein complex subunit organizationGO:00718223020.041
regulation of protein metabolic processGO:00512462890.041
epithelium developmentGO:0060429960.041
multicellular organism reproductionGO:00325042330.041
metal ion homeostasisGO:00550651860.041
liver developmentGO:0001889900.041
regulation of membrane potentialGO:00423911100.040
response to hexoseGO:00097461440.040
leukocyte activationGO:0045321760.039
reproductionGO:00000032450.039
monocarboxylic acid metabolic processGO:00327871520.039
neuron differentiationGO:00301823680.039
positive regulation of rna biosynthetic processGO:19026801970.039
rna biosynthetic processGO:00327743800.039
response to estradiolGO:00323551640.038
divalent inorganic cation homeostasisGO:00725071650.038
gland developmentGO:00487321550.038
regulation of immune system processGO:00026821230.038
response to metal ionGO:00100382530.038
negative regulation of macromolecule metabolic processGO:00106052600.038
negative regulation of macromolecule biosynthetic processGO:00105581480.037
regulation of cell developmentGO:00602842630.037
response to hypoxiaGO:00016662310.037
defense responseGO:00069521940.037
tissue developmentGO:00098882520.037
positive regulation of protein modification processGO:00314011420.037
regulation of endothelial cell differentiationGO:004560140.037
intracellular signal transductionGO:00355563140.036
positive regulation of cell differentiationGO:00455972170.036
heart contractionGO:0060047570.036
glomerular epithelial cell differentiationGO:007231120.036
chemical homeostasisGO:00488782920.036
regulation of nucleic acid templated transcriptionGO:19035063800.036
localization of cellGO:00516742020.035
regulation of rna biosynthetic processGO:20011413810.035
single organism catabolic processGO:00447122830.035
response to monosaccharideGO:00342841590.035
regulation of peptide transportGO:0090087870.035
response to mechanical stimulusGO:00096121340.035
amide transportGO:00428861050.035
negative regulation of transportGO:00510511360.035
positive regulation of protein phosphorylationGO:00019341350.035
regulation of response to external stimulusGO:00321011060.034
positive regulation of rna metabolic processGO:00512542030.034
regulation of neurogenesisGO:00507672470.034
monovalent inorganic cation transportGO:00156721720.034
epithelial cell differentiationGO:0030855710.034
circulatory system processGO:00030131830.034
positive regulation of cell developmentGO:00107201760.034
neuron developmentGO:00486662860.034
central nervous system developmentGO:00074173110.034
mesoderm developmentGO:000749820.034
response to estrogenGO:00436272320.033
anion transportGO:00068201780.033
sensory perceptionGO:00076001010.033
rna metabolic processGO:00160704060.033
reproductive processGO:00224143720.033
purine nucleotide metabolic processGO:00061632290.033
macromolecular complex assemblyGO:00650032730.033
positive regulation of cellular protein metabolic processGO:00322701670.033
positive regulation of phosphorus metabolic processGO:00105622620.033
positive regulation of macromolecule biosynthetic processGO:00105572470.033
b cell differentiationGO:003018320.033
negative regulation of biosynthetic processGO:00098901680.033
response to woundingGO:00096112540.033
negative regulation of nucleobase containing compound metabolic processGO:00459341530.032
response to oxidative stressGO:00069791860.032
negative regulation of phosphorus metabolic processGO:0010563800.032
cell motilityGO:00488702020.032
leukocyte differentiationGO:0002521300.032
protein complex assemblyGO:00064612630.032
sensory perception of painGO:0019233730.032
positive regulation of molecular functionGO:00440932300.032
protein heterooligomerizationGO:0051291890.032
ribonucleotide metabolic processGO:00092592310.032
artery developmentGO:006084030.031
organ regenerationGO:00311001010.031
regulation of transferase activityGO:00513381230.031
positive regulation of nervous system developmentGO:00519621780.031
signal releaseGO:00230611450.031
lymphocyte activationGO:0046649430.030
organonitrogen compound catabolic processGO:19015651790.030
rhythmic processGO:00485111560.030
sulfur compound metabolic processGO:0006790700.030
response to external biotic stimulusGO:00432072210.030
purine containing compound metabolic processGO:00725212530.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.029
regulation of cellular localizationGO:00603412630.029
regulation of locomotionGO:00400121480.029
organelle organizationGO:00069962660.029
tube developmentGO:0035295890.029
response to other organismGO:00517072200.029
secretion by cellGO:00329402480.029
positive regulation of gene expressionGO:00106282440.029
multi organism reproductive processGO:00447032620.029
regulation of cell motilityGO:20001451310.029
catabolic processGO:00090563510.029
maintenance of locationGO:0051235170.029
regulation of secretion by cellGO:19035302080.028
regulation of homeostatic processGO:00328441010.028
negative regulation of response to stimulusGO:00485851550.028
brain developmentGO:00074202470.028
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.028
negative regulation of apoptotic processGO:00430661810.028
steroid metabolic processGO:0008202730.028
organophosphate biosynthetic processGO:00904071430.028
sensory organ developmentGO:0007423740.028
peptide transportGO:0015833970.028
regulation of protein phosphorylationGO:00019321830.028
sex differentiationGO:00075481130.028
taxisGO:0042330670.028
skeletal system morphogenesisGO:0048705120.028
positive regulation of secretionGO:00510471400.028
immune system developmentGO:0002520410.028
purine ribonucleotide metabolic processGO:00091502270.028
lipid metabolic processGO:00066292830.028
protein oligomerizationGO:00512591910.027
negative regulation of neurogenesisGO:0050768780.027
nucleoside phosphate metabolic processGO:00067532830.027
response to biotic stimulusGO:00096072260.027
positive regulation of signalingGO:00230562700.027
cellular modified amino acid metabolic processGO:0006575610.027
positive regulation of phosphorylationGO:00423271770.027
organ morphogenesisGO:0009887750.027
regulation of cellular component movementGO:00512701500.026
regulation of neuron deathGO:19012141150.026
vasculogenesisGO:000157030.026
positive regulation of programmed cell deathGO:00430681570.026
spindle organizationGO:000705120.026
cellular metal ion homeostasisGO:00068751720.026
muscle system processGO:00030121150.026
agingGO:00075682410.026
chemotaxisGO:0006935660.025
muscle contractionGO:0006936880.025
inflammatory responseGO:00069541500.025
cellular lipid metabolic processGO:00442552080.025
regulation of blood circulationGO:19035221100.025
regulation of smooth muscle cell proliferationGO:0048660750.025
forebrain developmentGO:0030900980.025
digestive system developmentGO:0055123410.025
single organism intracellular transportGO:19025821660.025
cellular response to steroid hormone stimulusGO:0071383930.025
potassium ion transportGO:0006813970.024
response to vitaminGO:00332731310.024
cellular homeostasisGO:00197252520.024
hemopoiesisGO:0030097340.024
multicellular organism growthGO:003526410.024
cellular component movementGO:00069282480.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.024
intracellular transportGO:00469071850.024
immune responseGO:00069551040.024
cellular catabolic processGO:00442482950.024
cellular response to glucocorticoid stimulusGO:0071385680.024
negative regulation of signalingGO:00230571570.024
lipid biosynthetic processGO:00086101280.024
developmental growthGO:00485891000.023
aromatic compound catabolic processGO:00194391680.023
cell migrationGO:00164771970.023
positive regulation of cellular amine metabolic processGO:003324030.023
glial cell differentiationGO:0010001650.023
organic hydroxy compound metabolic processGO:19016151150.023
positive regulation of cell proliferationGO:00082842490.023
negative regulation of peptide hormone secretionGO:0090278300.023
neuron projection developmentGO:00311752730.023
insulin secretionGO:0030073690.023
reactive oxygen species metabolic processGO:0072593370.023
negative regulation of cellular biosynthetic processGO:00313271610.023
nucleotide metabolic processGO:00091172790.023
heart morphogenesisGO:000300730.023
action potentialGO:0001508540.023
regulation of ion transmembrane transportGO:00347651210.023
regulation of transmembrane transportGO:00347621220.023
carbohydrate derivative biosynthetic processGO:19011371240.023
negative regulation of secretionGO:0051048820.022
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.022
ribose phosphate metabolic processGO:00196932350.022
regulation of blood pressureGO:0008217830.022
neuronal action potentialGO:0019228350.022
positive regulation of transportGO:00510502450.022
cation homeostasisGO:00550801950.022
regulation of organ formationGO:000315620.022
regulation of vesicle mediated transportGO:0060627810.022
heart processGO:0003015570.022
cell adhesionGO:00071551100.022
mesenchymal cell proliferationGO:001046340.022
response to reactive oxygen speciesGO:00003021200.022
regulation of muscle contractionGO:0006937530.022
cofactor metabolic processGO:0051186950.022
positive regulation of phosphate metabolic processGO:00459372620.021
glomerular visceral epithelial cell developmentGO:007201520.021
heterocycle catabolic processGO:00467001670.021
negative regulation of rna metabolic processGO:00512531230.021
negative regulation of multicellular organismal processGO:00512412030.021
organonitrogen compound biosynthetic processGO:19015661670.021
cellular cation homeostasisGO:00300031800.021
regulation of blood vessel sizeGO:0050880890.021
gastrulationGO:000736920.021
negative regulation of programmed cell deathGO:00430691830.021
growthGO:00400071650.021
regulation of intracellular signal transductionGO:19025312180.021
cellular response to stressGO:00335542690.021
cytoskeleton organizationGO:00070101110.021
negative regulation of cell communicationGO:00106481580.021
renal system developmentGO:0072001670.021
bone developmentGO:0060348250.021
reproductive system developmentGO:00614581280.021
axis specificationGO:000979840.021
proteolysisGO:00065081750.021
cellular ion homeostasisGO:00068731840.021
regulation of cell migrationGO:00303341280.021
regulation of protein kinase activityGO:00458591050.020
cell cycleGO:00070491010.020
developmental process involved in reproductionGO:00030061590.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
regulation of tube sizeGO:0035150890.020
negative regulation of rna biosynthetic processGO:19026791180.020
intracellular receptor signaling pathwayGO:0030522350.020
axon developmentGO:0061564960.020
regulation of skeletal muscle tissue regenerationGO:004341620.020
response to ionizing radiationGO:0010212590.020
embryonic skeletal system developmentGO:004870630.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
positive regulation of secretion by cellGO:19035321280.020
developmental inductionGO:003112820.020
cellular calcium ion homeostasisGO:00068741600.020
negative regulation of neuron differentiationGO:0045665620.019
regulation of mapk cascadeGO:00434081160.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
protein transportGO:00150311320.019
organic cyclic compound catabolic processGO:19013611750.019
heart developmentGO:0007507720.019
lipid storageGO:001991510.019
negative regulation of molecular functionGO:00440921330.019
positive regulation of apoptotic processGO:00430651540.019
positive regulation of kinase activityGO:0033674770.019
response to dexamethasoneGO:0071548490.019
vasculature developmentGO:0001944700.019
coenzyme metabolic processGO:0006732860.019
cell morphogenesisGO:00009021420.019
development of primary sexual characteristicsGO:00451371070.019
response to alkaloidGO:00432791320.019
gliogenesisGO:0042063930.019
eye developmentGO:0001654500.019
regulation of muscle system processGO:0090257790.019
protein localizationGO:00081041910.019
fatty acid biosynthetic processGO:0006633330.018
respiratory system developmentGO:0060541450.018
circulatory system developmentGO:00723591340.018
cytokine mediated signaling pathwayGO:0019221430.018
synaptic transmissionGO:00072682350.018
nucleoside metabolic processGO:00091161790.018
transmission of nerve impulseGO:0019226420.018
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.018
single organism organelle organizationGO:19025891800.018
negative regulation of signal transductionGO:0009968830.018
lipid localizationGO:0010876620.018
hormone metabolic processGO:0042445690.018
peptide hormone secretionGO:0030072840.018
negative regulation of phosphate metabolic processGO:0045936800.018
negative regulation of transcription dna templatedGO:00458921160.018
urogenital system developmentGO:0001655780.018
regulation of metal ion transportGO:00109591180.018
peptide secretionGO:0002790860.018
regulation of body fluid levelsGO:0050878900.018
regulation of peptide secretionGO:0002791820.018
behaviorGO:00076102050.018
activation of protein kinase activityGO:0032147470.018
insulin like growth factor receptor signaling pathwayGO:004800930.017
multicellular organismal reproductive processGO:00486092330.017
negative regulation of cellular component organizationGO:0051129830.017
cellular nitrogen compound catabolic processGO:00442701630.017
regulation of interleukin 1 secretionGO:005070430.017
salivary gland developmentGO:000743130.017
blood vessel developmentGO:0001568690.017
signal transduction by phosphorylationGO:00230141440.017
actin filament based processGO:0030029860.017
positive regulation of ion transportGO:0043270940.017
telencephalon developmentGO:0021537620.017
positive regulation of neuron differentiationGO:00456661260.017
defecationGO:003042110.017
regulation of anatomical structure sizeGO:00900661350.017
nucleoside phosphate biosynthetic processGO:19012931020.017
actin cytoskeleton organizationGO:0030036730.016
cellular hormone metabolic processGO:0034754490.016
camera type eye developmentGO:0043010480.016
peptidyl tyrosine modificationGO:0018212720.016
coronary vasculature morphogenesisGO:006097730.016
activation of jak2 kinase activityGO:004297720.016
alcohol metabolic processGO:0006066770.016
endocytosisGO:0006897840.016
response to symbiontGO:000960810.016
salivary gland morphogenesisGO:000743510.016
positive regulation of locomotionGO:00400171020.016
cell type specific apoptotic processGO:00972851340.016
regulation of lipid metabolic processGO:0019216680.016
response to ketoneGO:19016541820.016
reproductive structure developmentGO:00486081280.016
development of primary female sexual characteristicsGO:0046545560.016
regulation of response to woundingGO:1903034690.016
regulation of leukocyte activationGO:0002694450.016
ribonucleoside metabolic processGO:00091191740.016
erythrocyte differentiationGO:003021810.016
vascular process in circulatory systemGO:0003018960.016
positive regulation of cell deathGO:00109421840.016
potassium ion transmembrane transportGO:0071805710.016
lymphoid progenitor cell differentiationGO:000232020.016
negative regulation of cardiac muscle tissue developmentGO:005502630.015
myeloid leukocyte differentiationGO:0002573200.015
glycerolipid metabolic processGO:0046486670.015
purine containing compound biosynthetic processGO:0072522850.015
sequestering of metal ionGO:005123890.015
ensheathment of neuronsGO:0007272400.015
purine ribonucleotide biosynthetic processGO:0009152810.015
cellular response to acid chemicalGO:0071229750.015
regulation of phosphorylationGO:00423252480.015
neuron deathGO:00709971270.015
carbohydrate metabolic processGO:00059751300.015
negative regulation of catalytic activityGO:00430861030.015
gonad developmentGO:00084061040.015
cellular response to cytokine stimulusGO:00713451270.015
nucleotide biosynthetic processGO:0009165980.015
cardiac chamber developmentGO:000320510.015
negative regulation of protein metabolic processGO:00512481140.015
eye morphogenesisGO:004859240.015
negative regulation of developmental processGO:00510931250.015
negative regulation of protein phosphorylationGO:0001933440.015
cellular response to external stimulusGO:00714961180.015
purine ribonucleoside metabolic processGO:00461281680.015
female sex differentiationGO:0046660590.015
negative regulation of cellular protein metabolic processGO:00322691060.015
axonogenesisGO:0007409710.015
chromosome segregationGO:000705920.015
g protein coupled receptor signaling pathwayGO:00071862420.015
small molecule biosynthetic processGO:00442831240.014
limbic system developmentGO:0021761380.014
hormone mediated signaling pathwayGO:0009755230.014
purine nucleotide biosynthetic processGO:0006164830.014
embryonic pattern specificationGO:000988010.014
myelinationGO:0042552390.014
interleukin 1 beta secretionGO:005070230.014
glycosyl compound metabolic processGO:19016571820.014
positive regulation of intracellular signal transductionGO:19025331380.014
male gamete generationGO:0048232990.014
positive regulation of angiogenesisGO:0045766280.014
multicellular organismal signalingGO:0035637440.014
nucleoside triphosphate metabolic processGO:00091411440.014

Enpep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.030
disease of cellular proliferationDOID:1456600.030
gastrointestinal system cancerDOID:311900.030
cancerDOID:16200.030
urinary system diseaseDOID:1800.030
disease of anatomical entityDOID:700.030
musculoskeletal system diseaseDOID:1700.028
disease of metabolismDOID:001466700.026
gastrointestinal system diseaseDOID:7700.026
kidney diseaseDOID:55700.025
cardiovascular system diseaseDOID:128700.024
nervous system diseaseDOID:86300.023
connective tissue diseaseDOID:6500.018
inherited metabolic disorderDOID:65500.014