Rattus norvegicus

23 known processes

Slc5a5

solute carrier family 5 (sodium iodide symporter), member 5

(Aliases: Nis)

Slc5a5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.764
cellular response to endogenous stimulusGO:00714953770.674
Human
cation transportGO:00068123820.642
cell cell signalingGO:00072673350.570
inorganic ion transmembrane transportGO:00986602290.525
response to nutrientGO:00075842480.488
metal ion transportGO:00300012890.375
response to external biotic stimulusGO:00432072210.364
response to biotic stimulusGO:00096072260.354
positive regulation of multicellular organismal processGO:00512403870.351
inorganic cation transmembrane transportGO:00986622020.342
cellular response to lipidGO:00713962010.337
response to estradiolGO:00323551640.330
response to woundingGO:00096112540.329
response to cytokineGO:00340972150.314
cellular response to hormone stimulusGO:00328702470.274
Human
cellular response to stressGO:00335542690.267
response to estrogenGO:00436272320.248
muscle contractionGO:0006936880.245
response to peptideGO:19016522920.244
cellular response to oxygen containing compoundGO:19017013860.226
Human
response to inorganic substanceGO:00100353770.225
regulation of multicellular organismal developmentGO:20000263760.218
secretionGO:00469033070.212
localization of cellGO:00516742020.212
cellular response to external stimulusGO:00714961180.207
cellular component movementGO:00069282480.204
cation transmembrane transportGO:00986552630.201
anatomical structure morphogenesisGO:00096532980.191
striated muscle contractionGO:0006941440.184
neurological system processGO:00508772190.181
anion transmembrane transportGO:0098656770.180
Rat
cell motilityGO:00488702020.175
regulation of locomotionGO:00400121480.170
nitrogen compound transportGO:00717052290.166
Rat
action potentialGO:0001508540.166
response to nutrient levelsGO:00316673700.164
cellular response to abiotic stimulusGO:0071214850.159
response to lipopolysaccharideGO:00324961910.157
cellular component biogenesisGO:00440853680.151
regulation of cellular component movementGO:00512701500.146
cell migrationGO:00164771970.145
response to extracellular stimulusGO:00099913800.145
response to peptide hormoneGO:00434342780.144
macromolecular complex assemblyGO:00650032730.139
response to oxygen levelsGO:00704822650.137
cellular response to histamineGO:007142030.136
response to hypoxiaGO:00016662310.132
positive regulation of cell motilityGO:2000147970.132
regulation of metal ion transportGO:00109591180.132
regulation of cell proliferationGO:00421273590.130
response to corticosteroidGO:00319602350.130
female gonad developmentGO:0008585530.123
regulation of membrane potentialGO:00423911100.121
response to molecule of bacterial originGO:00022371940.121
potassium ion transportGO:0006813970.119
response to metal ionGO:00100382530.119
neuron developmentGO:00486662860.116
protein complex biogenesisGO:00702712630.114
protein complex assemblyGO:00064612630.114
reproductive processGO:00224143720.113
response to glucocorticoidGO:00513842230.110
circulatory system developmentGO:00723591340.109
locomotionGO:00400112370.108
synaptic transmissionGO:00072682350.108
regulation of ion transportGO:00432692450.108
protein oligomerizationGO:00512591910.107
regulation of neuron differentiationGO:00456642080.107
programmed cell deathGO:00125013920.106
schwann cell migrationGO:003613520.105
sodium ion transportGO:0006814820.103
organic acid metabolic processGO:00060822920.103
response to decreased oxygen levelsGO:00362932370.100
response to vitaminGO:00332731310.100
synaptic transmission glycinergicGO:006001220.100
homeostatic processGO:00425923310.098
carboxylic acid transportGO:00469421150.098
Rat
regulation of cellular component organizationGO:00511283680.096
organic anion transportGO:00157111320.095
Rat
behaviorGO:00076102050.095
positive regulation of programmed cell deathGO:00430681570.094
cellular response to alcoholGO:0097306870.093
divalent inorganic cation transportGO:00725111340.089
regulation of cell motilityGO:20001451310.088
cellular chemical homeostasisGO:00550822470.088
regulation of cell migrationGO:00303341280.087
apoptotic processGO:00069153810.087
blood circulationGO:00080151830.086
response to alkaloidGO:00432791320.086
central nervous system developmentGO:00074173110.086
regulation of cell projection organizationGO:00313441750.084
calcium ion transportGO:00068161310.084
heart contractionGO:0060047570.083
ion transmembrane transportGO:00342203650.081
positive regulation of cell developmentGO:00107201760.080
response to mechanical stimulusGO:00096121340.080
oxoacid metabolic processGO:00434362900.079
response to acid chemicalGO:00011012220.078
response to other organismGO:00517072200.076
regulation of cell cycleGO:0051726730.074
multi multicellular organism processGO:00447061380.074
regulation of synaptic transmissionGO:00508041410.074
positive regulation of cell proliferationGO:00082842490.073
circulatory system processGO:00030131830.073
neuron differentiationGO:00301823680.073
positive regulation of developmental processGO:00510942830.072
positive regulation of transportGO:00510502450.071
calcium ion homeostasisGO:00550741620.070
cellular cation homeostasisGO:00300031800.069
tissue developmentGO:00098882520.069
response to ethanolGO:00454711620.068
reproductive system developmentGO:00614581280.068
biological adhesionGO:00226101100.068
response to radiationGO:00093141370.067
protein complex subunit organizationGO:00718223020.067
agingGO:00075682410.067
positive regulation of cellular component organizationGO:00511302000.066
negative regulation of multicellular organismal processGO:00512412030.065
positive regulation of cell differentiationGO:00455972170.065
macromolecular complex subunit organizationGO:00439333390.064
organic acid transportGO:00158491160.064
Rat
positive regulation of cell deathGO:00109421840.063
monovalent inorganic cation transportGO:00156721720.062
regulation of cell differentiationGO:00455953200.062
g protein coupled receptor signaling pathwayGO:00071862420.062
chemical homeostasisGO:00488782920.062
organ morphogenesisGO:0009887750.062
regulation of cell adhesionGO:0030155520.061
transmission of nerve impulseGO:0019226420.059
multicellular organismal reproductive processGO:00486092330.059
response to vitamin dGO:0033280340.058
cellular response to organic cyclic compoundGO:00714072020.058
Human
regulation of nervous system developmentGO:00519602640.058
regulation of blood pressureGO:0008217830.057
regulation of programmed cell deathGO:00430673410.056
developmental growthGO:00485891000.056
anion transportGO:00068201780.056
neuron projection developmentGO:00311752730.056
regenerationGO:00310991630.056
proteolysisGO:00065081750.056
regulation of secretionGO:00510462240.055
positive regulation of ion transportGO:0043270940.054
muscle system processGO:00030121150.053
muscle cell proliferationGO:0033002840.053
detection of stimulusGO:0051606240.053
cellular homeostasisGO:00197252520.053
response to transition metal nanoparticleGO:19902671220.053
regulation of apoptotic processGO:00429813350.052
response to testosteroneGO:0033574550.052
cardiovascular system developmentGO:00723581340.052
divalent metal ion transportGO:00708381320.051
amino acid transportGO:0006865700.051
Rat
regulation of transporter activityGO:0032409500.051
positive regulation of secretion by cellGO:19035321280.051
inflammatory responseGO:00069541500.051
immune system processGO:00023762040.050
regulation of system processGO:00440572080.050
rhythmic processGO:00485111560.050
cellular metal ion homeostasisGO:00068751720.050
cell adhesionGO:00071551100.050
regulation of response to external stimulusGO:00321011060.050
lipid metabolic processGO:00066292830.049
cardiac muscle contractionGO:0060048270.049
positive regulation of phosphate metabolic processGO:00459372620.049
regulation of neurogenesisGO:00507672470.049
cellular component assemblyGO:00226073600.049
sensory perceptionGO:00076001010.048
regulation of cell developmentGO:00602842630.048
response to ketoneGO:19016541820.048
response to calcium ionGO:0051592590.047
cellular response to steroid hormone stimulusGO:0071383930.047
negative regulation of cell proliferationGO:00082851190.047
tonic smooth muscle contractionGO:001482040.047
cellular ion homeostasisGO:00068731840.047
cellular response to cytokine stimulusGO:00713451270.046
endocytosisGO:0006897840.046
response to bacteriumGO:00096172000.046
organic hydroxy compound transportGO:0015850770.046
response to vitamin eGO:0033197240.046
taxisGO:0042330670.046
choline transportGO:001587140.046
regulation of phosphorus metabolic processGO:00511743490.045
regulation of anatomical structure morphogenesisGO:00226031410.045
negative regulation of transportGO:00510511360.045
cell growthGO:00160491040.045
regulation of neural precursor cell proliferationGO:2000177160.044
positive regulation of apoptotic processGO:00430651540.044
negative regulation of cellular metabolic processGO:00313242810.044
regulation of cell growthGO:0001558850.044
reproductive structure developmentGO:00486081280.044
lipid biosynthetic processGO:00086101280.044
steroid metabolic processGO:0008202730.043
ovulation cycle processGO:0022602500.042
wound healingGO:00420601220.042
regulation of cellular localizationGO:00603412630.041
positive regulation of secretionGO:00510471400.041
amide transportGO:00428861050.041
Rat
neuron deathGO:00709971270.040
regulation of signal transductionGO:00099663180.040
heart processGO:0003015570.040
negative regulation of cell differentiationGO:0045596990.038
smooth muscle cell proliferationGO:0048659770.037
regulation of blood vessel sizeGO:0050880890.037
blood vessel developmentGO:0001568690.037
single organism organelle organizationGO:19025891800.037
epithelial cell migrationGO:0010631190.037
detection of abiotic stimulusGO:0009582130.036
positive regulation of nervous system developmentGO:00519621780.035
chemotaxisGO:0006935660.035
regulation of tube sizeGO:0035150890.035
positive regulation of cell migrationGO:0030335960.035
positive regulation of epidermis developmentGO:004568410.035
epithelium developmentGO:0060429960.034
multicellular organismal signalingGO:0035637440.034
response to histamineGO:003477630.034
negative regulation of developmental processGO:00510931250.034
amine metabolic processGO:0009308380.034
positive regulation of cellular component movementGO:00512721020.033
organelle organizationGO:00069962660.033
positive regulation of cellular amino acid metabolic processGO:004576410.033
inflammatory cell apoptotic processGO:000692550.032
positive regulation of locomotionGO:00400171020.032
negative regulation of response to stimulusGO:00485851550.031
positive regulation of neurogenesisGO:00507691650.031
calcium mediated signalingGO:0019722230.031
gland developmentGO:00487321550.031
heart growthGO:0060419200.031
regulation of blood circulationGO:19035221100.031
ion homeostasisGO:00508012120.031
regulation of muscle system processGO:0090257790.030
cellular response to peptide hormone stimulusGO:00713751200.030
reproductionGO:00000032450.030
neuromuscular processGO:005090520.030
brain developmentGO:00074202470.030
cellular response to corticosteroid stimulusGO:0071384690.029
regulation of synaptic plasticityGO:0048167700.029
cellular response to nitrogen compoundGO:19016992100.029
Human
regulation of cardiac muscle contractionGO:0055117170.029
negative regulation of cell deathGO:00605482290.029
fat cell proliferationGO:007034120.029
single organism intracellular transportGO:19025821660.029
single organism reproductive processGO:00447022970.029
regulation of angiogenesisGO:0045765390.028
development of primary female sexual characteristicsGO:0046545560.028
tissue remodelingGO:0048771400.028
reactive oxygen species biosynthetic processGO:190340980.028
regulation of response to woundingGO:1903034690.028
angiogenesisGO:0001525530.027
single organism biosynthetic processGO:00447113420.027
response to hexoseGO:00097461440.027
catabolic processGO:00090563510.027
vesicle mediated transportGO:00161921810.027
negative regulation of nervous system developmentGO:0051961790.027
organic substance catabolic processGO:19015753160.027
cellular response to peptideGO:19016531330.027
regulation of transmembrane transporter activityGO:0022898490.026
regulation of catalytic activityGO:00507903040.026
phasic smooth muscle contractionGO:001482130.026
regulation of neuron projection developmentGO:00109751610.026
female sex differentiationGO:0046660590.026
regulation of growthGO:00400081050.026
cellular response to growth factor stimulusGO:00713631620.026
actin mediated cell contractionGO:0070252120.026
regulation of mapk cascadeGO:00434081160.026
regulation of phosphorylationGO:00423252480.026
reactive nitrogen species metabolic processGO:200105710.026
cellular response to extracellular stimulusGO:0031668730.025
organ growthGO:0035265240.025
regulation of calcium ion transportGO:0051924770.025
positive regulation of cellular protein metabolic processGO:00322701670.025
sensory perception of painGO:0019233730.025
response to retinoic acidGO:0032526630.025
cellular response to nutrient levelsGO:0031669600.025
axonogenesisGO:0007409710.025
response to activityGO:0014823730.024
secretion by cellGO:00329402480.024
cell projection organizationGO:00300303020.024
head developmentGO:00603222470.024
positive regulation of nitrogen compound metabolic processGO:00511733340.024
peptide transportGO:0015833970.024
regulation of epithelial cell proliferationGO:0050678490.024
negative regulation of response to woundingGO:1903035230.023
multicellular organism reproductionGO:00325042330.023
detection of external stimulusGO:0009581130.023
cellular ketone metabolic processGO:0042180510.023
single organism behaviorGO:00447081300.023
regulation of behaviorGO:0050795610.023
ovulation cycleGO:0042698670.023
regulation of sodium ion transportGO:0002028210.023
positive regulation of biosynthetic processGO:00098913190.023
bile acid and bile salt transportGO:0015721120.022
regulation of anatomical structure sizeGO:00900661350.022
angioblast cell migrationGO:003547610.022
cation homeostasisGO:00550801950.022
regulation of heart contractionGO:0008016480.022
positive regulation of cytoskeleton organizationGO:0051495260.022
nucleic acid templated transcriptionGO:00976593790.021
cellular amine metabolic processGO:0044106380.021
transcription dna templatedGO:00063513770.021
regulation of rna biosynthetic processGO:20011413810.021
positive regulation of heart contractionGO:0045823150.021
regulation of intracellular signal transductionGO:19025312180.021
negative regulation of metabolic processGO:00098923310.021
carbohydrate homeostasisGO:0033500750.021
cellular catabolic processGO:00442482950.021
cellular response to estradiol stimulusGO:0071392160.021
response to toxic substanceGO:00096361330.021
protein homooligomerizationGO:0051260910.021
negative regulation of macromolecule metabolic processGO:00106052600.021
cellular response to glucocorticoid stimulusGO:0071385680.021
rna biosynthetic processGO:00327743800.021
positive regulation of homeostatic processGO:0032846490.020
nucleobase containing small molecule metabolic processGO:00550863160.020
positive regulation of blood circulationGO:1903524650.020
regulation of ion transmembrane transporter activityGO:0032412480.020
cell activationGO:0001775970.020
positive regulation of mapk cascadeGO:0043410920.020
protein heterooligomerizationGO:0051291890.020
response to nicotineGO:0035094510.020
regulation of cellular protein metabolic processGO:00322682670.020
cellular response to mechanical stimulusGO:0071260480.020
establishment of protein localizationGO:00451841410.020
tube developmentGO:0035295890.020
growthGO:00400071650.020
negative regulation of molecular functionGO:00440921330.020
positive regulation of cellular amine metabolic processGO:003324030.019
cytosolic calcium ion homeostasisGO:00514801400.019
intracellular signal transductionGO:00355563140.019
female pregnancyGO:00075651220.019
protein localizationGO:00081041910.019
cell type specific apoptotic processGO:00972851340.019
positive regulation of signalingGO:00230562700.019
ensheathment of neuronsGO:0007272400.019
regulation of vasculature developmentGO:1901342440.019
regulation of protein metabolic processGO:00512462890.019
regulation of cellular ketone metabolic processGO:0010565270.019
positive regulation of phosphorus metabolic processGO:00105622620.019
regulation of phosphatidylinositol dephosphorylationGO:006030410.019
positive regulation of reactive oxygen species biosynthetic processGO:190342820.019
positive regulation of cellular biosynthetic processGO:00313282950.019
regulation of reactive oxygen species biosynthetic processGO:190342650.019
negative regulation of cellular biosynthetic processGO:00313271610.019
feeding behaviorGO:0007631530.019
defense responseGO:00069521940.019
potassium ion transmembrane transportGO:0071805710.018
dephosphorylationGO:0016311980.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
response to growth factorGO:00708481890.018
regulation of immune system processGO:00026821230.018
regulation of hydrolase activityGO:00513361430.018
endocrine system developmentGO:0035270300.018
response to hyperoxiaGO:0055093450.018
hormone transportGO:00099141210.018
response to glucoseGO:00097491360.018
organophosphate metabolic processGO:00196373700.018
oligopeptide transportGO:000685740.018
regulation of hormone levelsGO:00108171870.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
reactive oxygen species metabolic processGO:0072593370.017
positive regulation of molecular functionGO:00440932300.017
membrane hyperpolarizationGO:0060081110.017
organic cyclic compound catabolic processGO:19013611750.017
cellular response to acid chemicalGO:0071229750.017
synaptic transmission gabaergicGO:0051932220.017
neurotransmitter transportGO:0006836420.017
regulation of body fluid levelsGO:0050878900.017
tripeptide transportGO:004293920.017
negative regulation of biosynthetic processGO:00098901680.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
regulation of cation channel activityGO:2001257230.017
axon developmentGO:0061564960.017
ras protein signal transductionGO:0007265290.017
lateral ventricle developmentGO:002167010.017
single organism catabolic processGO:00447122830.016
positive regulation of phagocytosis engulfmentGO:006010040.016
regulation of fat cell differentiationGO:004559830.016
vasodilationGO:0042311440.016
heart developmentGO:0007507720.016
positive regulation of protein serine threonine kinase activityGO:0071902520.016
response to monosaccharideGO:00342841590.016
regulation of secretion by cellGO:19035302080.016
glutathione transportGO:003463520.016
urinary tract smooth muscle contractionGO:001484840.016
synaptic growth at neuromuscular junctionGO:005112410.016
glycogen metabolic processGO:0005977230.016
cellular macromolecule localizationGO:00707271220.016
response to tumor necrosis factorGO:0034612560.016
hindlimb morphogenesisGO:003513720.016
positive regulation of growthGO:0045927550.016
heterocycle catabolic processGO:00467001670.016
regulation of cellular amine metabolic processGO:003323880.016
regulation of response to stressGO:00801341260.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
development of primary sexual characteristicsGO:00451371070.016
leukocyte migrationGO:0050900380.016
peptide hormone secretionGO:0030072840.016
hormone secretionGO:00468791150.016
sex differentiationGO:00075481130.016
response to insulinGO:00328681330.016
signal releaseGO:00230611450.016
ameboidal type cell migrationGO:0001667260.016
renal system processGO:0003014400.015
regulation of neurological system processGO:0031644430.015
neuronal action potentialGO:0019228350.015
cell morphogenesisGO:00009021420.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.015
muscle cell differentiationGO:0042692520.015
positive regulation of nitric oxide biosynthetic processGO:0045429140.015
long chain fatty acid metabolic processGO:0001676320.015
ossificationGO:0001503700.015
regulation of sensory perception of painGO:0051930290.015
rho protein signal transductionGO:0007266110.015
regulation of muscle tissue developmentGO:1901861250.015
signal transduction by phosphorylationGO:00230141440.015
regulation of protein modification processGO:00313991940.015
regulation of cellular amino acid metabolic processGO:000652120.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
excretionGO:0007588240.015
catecholamine secretionGO:0050432330.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
positive regulation of phosphorylationGO:00423271770.015
actin filament based processGO:0030029860.015
regulation of homeostatic processGO:00328441010.015
membrane organizationGO:0061024940.015
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.014
hyperosmotic responseGO:0006972180.014
glucan metabolic processGO:0044042230.014
nucleoside phosphate metabolic processGO:00067532830.014
hepaticobiliary system developmentGO:0061008900.014
modified amino acid transportGO:0072337120.014
Rat
positive regulation of organelle organizationGO:0010638480.014
regulation of defense responseGO:0031347680.014
interleukin 18 productionGO:003262110.014
positive regulation of intracellular signal transductionGO:19025331380.014
regulation of transcription dna templatedGO:00063553740.014
neuron apoptotic processGO:0051402880.014
regulation of vesicle mediated transportGO:0060627810.014
regulation of transmembrane transportGO:00347621220.014
cell projection morphogenesisGO:00488581230.014
urinary bladder smooth muscle contractionGO:001483240.014
fibroblast proliferationGO:0048144220.013
liver developmentGO:0001889900.013
platelet aggregationGO:007052740.013
acetate ester biosynthetic processGO:190062020.013
protein phosphorylationGO:00064683450.013
transcription from rna polymerase ii promoterGO:00063662520.013
regulation of ion transmembrane transportGO:00347651210.013
regulation of amine transportGO:0051952540.013
mapk cascadeGO:00001651400.013
positive regulation of protein phosphorylationGO:00019341350.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.013
sexual reproductionGO:00199531480.013
negative regulation of neuron differentiationGO:0045665620.013
cellular amino acid metabolic processGO:00065201070.013
response to fatty acidGO:0070542650.013
muscle structure developmentGO:0061061870.013
secretion by tissueGO:0032941370.013
response to coldGO:0009409290.013
regulation of smooth muscle cell proliferationGO:0048660750.013
regulation of molecular functionGO:00650093980.013
rna metabolic processGO:00160704060.013
regulation of cell cycle processGO:0010564310.013
learning or memoryGO:0007611900.013
positive regulation of cell growthGO:0030307440.013
positive regulation of interleukin 18 productionGO:003274110.013
response to reactive oxygen speciesGO:00003021200.012
response to vitamin aGO:0033189360.012
positive regulation of hydrolase activityGO:0051345860.012
positive regulation of gene expressionGO:00106282440.012
regulation of inflammatory responseGO:0050727480.012
bile acid secretionGO:003278250.012
positive regulation of lipid metabolic processGO:0045834330.012
response to cgmpGO:007030530.012
circadian rhythmGO:0007623880.012
inorganic anion transportGO:0015698410.012
protein transportGO:00150311320.012
positive regulation of saliva secretionGO:004687830.012
positive regulation of purine nucleotide biosynthetic processGO:1900373360.012
synapse organizationGO:0050808460.012
cardiac muscle cell contractionGO:0086003100.012
immunoglobulin mediated immune responseGO:001606440.012
regulation of neuron apoptotic processGO:0043523830.012
regulation of lipid metabolic processGO:0019216680.012
regulation of neurotransmitter secretionGO:0046928190.012
response to purine containing compoundGO:00140741260.012
Human
negative regulation of cell developmentGO:0010721820.012
gamete generationGO:00072761240.012
small gtpase mediated signal transductionGO:0007264360.012

Slc5a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.075
disease of anatomical entityDOID:700.075
Human
sensory system diseaseDOID:005015500.075
eye and adnexa diseaseDOID:149200.027
eye diseaseDOID:561400.020
central nervous system diseaseDOID:33100.018
cardiovascular system diseaseDOID:128700.017
retinal diseaseDOID:567900.014
retinal degenerationDOID:846600.014
cone rod dystrophyDOID:005057200.014