Rattus norvegicus

27 known processes

Slc6a5

solute carrier family 6 (neurotransmitter transporter, glycine), member 5

(Aliases: GLYT2)

Slc6a5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid transportGO:00469421150.231
reproductive structure developmentGO:00486081280.217
cation transportGO:00068123820.216
regulation of cell proliferationGO:00421273590.185
Rat
regulation of ion transportGO:00432692450.165
Rat
tissue developmentGO:00098882520.158
regulation of secretionGO:00510462240.154
Rat
reproductive processGO:00224143720.145
Rat
cation transmembrane transportGO:00986552630.145
cell cell signalingGO:00072673350.143
Human Rat
transmembrane transportGO:00550854120.136
single organism reproductive processGO:00447022970.130
Rat
reproductive system developmentGO:00614581280.118
organic anion transportGO:00157111320.116
response to inorganic substanceGO:00100353770.115
Rat
reproductionGO:00000032450.113
Rat
anion transportGO:00068201780.109
intracellular signal transductionGO:00355563140.106
ion transmembrane transportGO:00342203650.103
positive regulation of nitrogen compound metabolic processGO:00511733340.095
response to carbohydrateGO:00097431830.092
Rat
response to estrogenGO:00436272320.092
Rat
female pregnancyGO:00075651220.085
response to metal ionGO:00100382530.083
Rat
response to peptide hormoneGO:00434342780.083
inorganic ion transmembrane transportGO:00986602290.083
Human Rat
cellular chemical homeostasisGO:00550822470.082
Rat
locomotionGO:00400112370.080
cellular response to hormone stimulusGO:00328702470.078
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.077
negative regulation of cellular biosynthetic processGO:00313271610.076
response to extracellular stimulusGO:00099913800.076
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.076
sensory perceptionGO:00076001010.075
multicellular organismal reproductive processGO:00486092330.074
Rat
organic acid transportGO:00158491160.073
organonitrogen compound biosynthetic processGO:19015661670.072
brain developmentGO:00074202470.071
Rat
regulation of programmed cell deathGO:00430673410.071
apoptotic processGO:00069153810.070
monovalent inorganic cation transportGO:00156721720.070
Human Rat
regulation of hormone levelsGO:00108171870.070
negative regulation of biosynthetic processGO:00098901680.069
response to hydrogen peroxideGO:0042542890.067
limb morphogenesisGO:003510840.066
developmental process involved in reproductionGO:00030061590.063
inorganic cation transmembrane transportGO:00986622020.062
Human Rat
skeletal system developmentGO:0001501410.059
programmed cell deathGO:00125013920.058
ovulation cycleGO:0042698670.058
positive regulation of cellular biosynthetic processGO:00313282950.057
regulation of membrane potentialGO:00423911100.057
neurological system processGO:00508772190.057
Rat
positive regulation of developmental processGO:00510942830.055
homeostatic processGO:00425923310.055
Rat
response to nutrient levelsGO:00316673700.055
Rat
organic hydroxy compound metabolic processGO:19016151150.055
regulation of blood circulationGO:19035221100.055
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.054
response to monosaccharideGO:00342841590.054
cellular homeostasisGO:00197252520.054
Rat
cellular response to endogenous stimulusGO:00714953770.053
Rat
negative regulation of multicellular organismal processGO:00512412030.052
Rat
response to external biotic stimulusGO:00432072210.051
negative regulation of cell proliferationGO:00082851190.051
Rat
response to glucocorticoidGO:00513842230.050
multi organism reproductive processGO:00447032620.049
Rat
response to estradiolGO:00323551640.048
Rat
cell projection organizationGO:00300303020.046
anatomical structure morphogenesisGO:00096532980.045
neuron developmentGO:00486662860.045
regulation of apoptotic processGO:00429813350.045
regulation of phosphorus metabolic processGO:00511743490.045
cellular response to stressGO:00335542690.044
Rat
negative regulation of cellular metabolic processGO:00313242810.044
response to peptideGO:19016522920.043
lipid metabolic processGO:00066292830.043
negative regulation of signalingGO:00230571570.043
Rat
single organism biosynthetic processGO:00447113420.043
response to acid chemicalGO:00011012220.042
Rat
cardiovascular system developmentGO:00723581340.042
regulation of phosphate metabolic processGO:00192203490.040
positive regulation of biosynthetic processGO:00098913190.040
response to starvationGO:0042594590.039
chemical homeostasisGO:00488782920.039
Rat
response to corticosteroidGO:00319602350.039
cyclic nucleotide biosynthetic processGO:0009190630.039
positive regulation of macromolecule biosynthetic processGO:00105572470.039
positive regulation of cytosolic calcium ion concentrationGO:00072041220.039
cellular metal ion homeostasisGO:00068751720.038
regulation of phosphorylationGO:00423252480.038
nitrogen compound transportGO:00717052290.038
response to decreased oxygen levelsGO:00362932370.038
Rat
neuron projection developmentGO:00311752730.038
positive regulation of signalingGO:00230562700.038
sexual reproductionGO:00199531480.037
Rat
gonad developmentGO:00084061040.037
regulation of mapk cascadeGO:00434081160.037
cellular response to organic cyclic compoundGO:00714072020.037
Rat
bone developmentGO:0060348250.037
negative regulation of nucleobase containing compound metabolic processGO:00459341530.037
multicellular organism reproductionGO:00325042330.037
Rat
behaviorGO:00076102050.036
Rat
positive regulation of phosphate metabolic processGO:00459372620.036
cgmp biosynthetic processGO:0006182150.036
cellular response to lipidGO:00713962010.035
Rat
carbohydrate derivative metabolic processGO:19011353460.035
regulation of rna metabolic processGO:00512523910.035
cellular divalent inorganic cation homeostasisGO:00725031620.035
response to growth factorGO:00708481890.034
positive regulation of synaptic plasticityGO:003191530.034
ribose phosphate biosynthetic processGO:0046390870.034
divalent inorganic cation homeostasisGO:00725071650.034
response to nutrientGO:00075842480.034
Rat
purine containing compound biosynthetic processGO:0072522850.033
metal ion transportGO:00300012890.033
Human Rat
organophosphate biosynthetic processGO:00904071430.033
cellular ion homeostasisGO:00068731840.033
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
calcium ion homeostasisGO:00550741620.032
purine ribonucleotide metabolic processGO:00091502270.032
regulation of system processGO:00440572080.032
development of primary female sexual characteristicsGO:0046545560.031
development of primary sexual characteristicsGO:00451371070.031
cyclic nucleotide metabolic processGO:0009187800.031
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
response to hexoseGO:00097461440.031
sensory organ developmentGO:0007423740.031
negative regulation of metabolic processGO:00098923310.031
regulation of rna biosynthetic processGO:20011413810.030
cell communication involved in cardiac conductionGO:008606520.030
response to biotic stimulusGO:00096072260.030
positive regulation of cell communicationGO:00106472710.030
positive regulation of transcription dna templatedGO:00458931970.029
regenerationGO:00310991630.029
appendage morphogenesisGO:003510740.029
cellular response to oxygen containing compoundGO:19017013860.029
Rat
positive regulation of rna biosynthetic processGO:19026801970.028
regulation of nucleotide biosynthetic processGO:0030808470.028
lipid transportGO:0006869610.028
sex differentiationGO:00075481130.028
action potentialGO:0001508540.027
potassium ion transportGO:0006813970.027
single organism behaviorGO:00447081300.027
Rat
heart morphogenesisGO:000300730.027
monocarboxylic acid transportGO:0015718520.027
Rat
cellular component movementGO:00069282480.027
positive regulation of programmed cell deathGO:00430681570.027
negative regulation of nucleic acid templated transcriptionGO:19035071170.027
transcription dna templatedGO:00063513770.027
regulation of catalytic activityGO:00507903040.026
nucleotide biosynthetic processGO:0009165980.026
regulation of protein metabolic processGO:00512462890.026
regulation of cellular localizationGO:00603412630.026
catecholamine metabolic processGO:0006584190.025
regulation of erk1 and erk2 cascadeGO:0070372410.025
response to glucoseGO:00097491360.025
ribonucleotide metabolic processGO:00092592310.025
response to oxidative stressGO:00069791860.025
organophosphate metabolic processGO:00196373700.025
fear responseGO:004259690.024
vesicle mediated transportGO:00161921810.024
transcription from rna polymerase ii promoterGO:00063662520.024
negative regulation of programmed cell deathGO:00430691830.024
regulation of signal transductionGO:00099663180.024
response to retinoic acidGO:0032526630.024
Rat
regulation of secretion by cellGO:19035302080.024
purine ribonucleotide biosynthetic processGO:0009152810.024
negative regulation of apoptotic processGO:00430661810.024
response to cytokineGO:00340972150.023
response to light stimulusGO:0009416520.023
ensheathment of neuronsGO:0007272400.023
cellular response to growth factor stimulusGO:00713631620.023
response to radiationGO:00093141370.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
head developmentGO:00603222470.023
Rat
epithelium developmentGO:0060429960.022
protein oligomerizationGO:00512591910.022
Rat
regulation of camp biosynthetic processGO:0030817380.022
steroid metabolic processGO:0008202730.022
adult locomotory behaviorGO:000834440.022
regulation of dna metabolic processGO:0051052600.022
carbohydrate derivative biosynthetic processGO:19011371240.022
negative regulation of macromolecule metabolic processGO:00106052600.022
positive regulation of phosphorus metabolic processGO:00105622620.022
embryonic appendage morphogenesisGO:003511340.022
neuron differentiationGO:00301823680.022
Rat
positive regulation of catalytic activityGO:00430851840.021
cellular component assemblyGO:00226073600.021
Rat
negative regulation of rna biosynthetic processGO:19026791180.021
monocarboxylic acid metabolic processGO:00327871520.021
nucleotide metabolic processGO:00091172790.021
positive regulation of cell proliferationGO:00082842490.021
nucleobase containing small molecule metabolic processGO:00550863160.021
single organism organelle organizationGO:19025891800.021
neuropeptide signaling pathwayGO:0007218290.021
calcium ion transmembrane transportGO:0070588700.021
regulation of locomotionGO:00400121480.020
positive regulation of molecular functionGO:00440932300.020
negative regulation of rna metabolic processGO:00512531230.020
epithelial cell proliferationGO:0050673540.020
male sex differentiationGO:0046661640.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
regulation of organelle organizationGO:0033043800.020
embryonic limb morphogenesisGO:003032640.020
regulation of transmembrane transportGO:00347621220.019
negative regulation of cell deathGO:00605482290.019
cellular cation homeostasisGO:00300031800.019
dna metabolic processGO:0006259960.019
negative regulation of transcription dna templatedGO:00458921160.019
cellular lipid metabolic processGO:00442552080.019
catabolic processGO:00090563510.019
positive regulation of cellular component organizationGO:00511302000.019
proteolysisGO:00065081750.019
nucleoside phosphate biosynthetic processGO:19012931020.019
cellular component morphogenesisGO:00329891550.018
positive regulation of kinase activityGO:0033674770.018
g protein coupled receptor internalizationGO:000203130.018
regulation of nervous system developmentGO:00519602640.018
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.018
regulation of smooth muscle cell proliferationGO:0048660750.018
kidney developmentGO:0001822670.018
receptor metabolic processGO:0043112180.018
lipid localizationGO:0010876620.018
maintenance of locationGO:0051235170.018
male gonad developmentGO:0008584590.018
secretionGO:00469033070.018
Rat
rna metabolic processGO:00160704060.018
regulation of nucleic acid templated transcriptionGO:19035063800.017
ion homeostasisGO:00508012120.017
regulation of blood pressureGO:0008217830.017
regulation of intracellular signal transductionGO:19025312180.017
multicellular organismal response to stressGO:0033555250.017
female sex differentiationGO:0046660590.017
metal ion homeostasisGO:00550651860.017
signal releaseGO:00230611450.017
cellular response to extracellular stimulusGO:0031668730.017
neuronal action potentialGO:0019228350.017
spermatogenesisGO:0007283990.017
response to oxygen levelsGO:00704822650.017
Rat
positive regulation of hepatocyte differentiationGO:007036820.017
cellular calcium ion homeostasisGO:00068741600.017
muscle system processGO:00030121150.017
connective tissue developmentGO:0061448330.016
response to woundingGO:00096112540.016
response to ethanolGO:00454711620.016
Rat
eye developmentGO:0001654500.016
regulation of cyclic nucleotide biosynthetic processGO:0030802450.016
response to calcium ionGO:0051592590.016
Rat
small molecule biosynthetic processGO:00442831240.016
response to purine containing compoundGO:00140741260.016
Rat
positive regulation of cell deathGO:00109421840.016
cyclic purine nucleotide metabolic processGO:0052652620.016
response to reactive oxygen speciesGO:00003021200.016
angiogenesis involved in coronary vascular morphogenesisGO:006097830.016
female gonad developmentGO:0008585530.016
response to fluid shear stressGO:0034405160.016
negative regulation of signal transductionGO:0009968830.016
negative regulation of cell communicationGO:00106481580.016
Rat
purine containing compound metabolic processGO:00725212530.015
purine nucleotide metabolic processGO:00061632290.015
regulation of cyclic nucleotide metabolic processGO:0030799510.015
positive regulation of mapk cascadeGO:0043410920.015
regulation of cellular component organizationGO:00511283680.015
cellular response to nutrient levelsGO:0031669600.015
response to hypoxiaGO:00016662310.015
Rat
negative regulation of transportGO:00510511360.015
cellular catabolic processGO:00442482950.015
myelinationGO:0042552390.015
response to testosteroneGO:0033574550.015
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.015
positive regulation of hormone secretionGO:0046887650.015
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.015
cytosolic calcium ion homeostasisGO:00514801400.015
agingGO:00075682410.014
Rat
ionotropic glutamate receptor signaling pathwayGO:0035235340.014
regulation of cell migrationGO:00303341280.014
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.014
ossificationGO:0001503700.014
positive regulation of phosphorylationGO:00423271770.014
rhythmic processGO:00485111560.014
Rat
purine nucleotide biosynthetic processGO:0006164830.014
positive regulation of peptide hormone secretionGO:0090277500.014
regulation of hormone secretionGO:00468831060.014
positive regulation of multicellular organismal processGO:00512403870.014
positive regulation of signal transductionGO:00099671750.014
macromolecular complex assemblyGO:00650032730.014
Rat
cellular response to corticosteroid stimulusGO:0071384690.014
heart contractionGO:0060047570.014
mapk cascadeGO:00001651400.014
camp metabolic processGO:0046058630.014
positive regulation of nucleotide biosynthetic processGO:0030810360.014
positive regulation of rna metabolic processGO:00512542030.014
one carbon compound transportGO:001975550.014
nucleoside phosphate metabolic processGO:00067532830.013
smooth muscle cell proliferationGO:0048659770.013
protein complex biogenesisGO:00702712630.013
Rat
small gtpase mediated signal transductionGO:0007264360.013
reactive oxygen species metabolic processGO:0072593370.013
calcium ion transportGO:00068161310.013
gamete generationGO:00072761240.013
striated muscle contractionGO:0006941440.013
positive regulation of gene expressionGO:00106282440.013
regulation of multicellular organismal developmentGO:20000263760.013
Rat
axon ensheathmentGO:0008366400.013
alcohol metabolic processGO:0006066770.013
regulation of epithelial cell proliferationGO:0050678490.013
protein complex subunit organizationGO:00718223020.013
Rat
response to insulinGO:00328681330.013
positive regulation of action potentialGO:004576080.013
cellular response to vitamin eGO:007130630.012
alternative mrna splicing via spliceosomeGO:000038040.012
hormone transportGO:00099141210.012
intestinal absorptionGO:005089230.012
cardiac muscle cell contractionGO:0086003100.012
negative regulation of phosphorus metabolic processGO:0010563800.012
response to ketoneGO:19016541820.012
muscle cell proliferationGO:0033002840.012
negative regulation of response to stimulusGO:00485851550.012
secretion by cellGO:00329402480.012
response to ammonium ionGO:0060359710.012
Rat
mesoderm developmentGO:000749820.012
potassium ion transmembrane transportGO:0071805710.012
cation homeostasisGO:00550801950.012
negative regulation of cell cycle phase transitionGO:190198840.012
hormone secretionGO:00468791150.012
synaptic growth at neuromuscular junctionGO:005112410.012
response to vitaminGO:00332731310.012
lipid biosynthetic processGO:00086101280.012
positive regulation of peptide secretionGO:0002793520.012
cellular response to organonitrogen compoundGO:00714171970.012
Rat
receptor internalizationGO:0031623140.012
cellular amine metabolic processGO:0044106380.012
receptor mediated endocytosisGO:0006898420.012
regulation of purine nucleotide metabolic processGO:19005421150.011
ribose phosphate metabolic processGO:00196932350.011
development of primary male sexual characteristicsGO:0046546590.011
heart processGO:0003015570.011
regulation of transcription dna templatedGO:00063553740.011
ribonucleotide biosynthetic processGO:0009260850.011
glucose homeostasisGO:0042593750.011
cell morphogenesisGO:00009021420.011
cellular response to oxygen levelsGO:0071453600.011
brown fat cell proliferationGO:007034220.011
central nervous system developmentGO:00074173110.011
Rat
regulation of nucleotide metabolic processGO:00061401170.011
regulation of purine nucleotide biosynthetic processGO:1900371460.011
sodium ion transmembrane transportGO:0035725670.011
Human Rat
cellular response to starvationGO:0009267270.011
detection of visible lightGO:000958430.011
neuron apoptotic processGO:0051402880.011
organic acid metabolic processGO:00060822920.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
regulation of cell cycleGO:0051726730.011
hindlimb morphogenesisGO:003513720.011
cellular response to hexose stimulusGO:0071331650.011
amine metabolic processGO:0009308380.011
cell morphogenesis involved in differentiationGO:00009041190.011
sensory perception of painGO:0019233730.011
divalent inorganic cation transportGO:00725111340.011
nucleic acid templated transcriptionGO:00976593790.011
transmission of nerve impulseGO:0019226420.011
dendrite morphogenesisGO:0048813430.010
regulation of peptide secretionGO:0002791820.010
synaptic transmissionGO:00072682350.010
Human Rat
male gamete generationGO:0048232990.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
sodium ion transportGO:0006814820.010
Human Rat
regulation of cellular protein metabolic processGO:00322682670.010
response to nicotineGO:0035094510.010
Rat
negative regulation of secretionGO:0051048820.010
circulatory system developmentGO:00723591340.010

Slc6a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.024
connective tissue diseaseDOID:6500.024
bone diseaseDOID:008000100.011
disease of metabolismDOID:001466700.011
cardiovascular system diseaseDOID:128700.010