Rattus norvegicus

16 known processes

Irx4

iroquois homeobox 4

Irx4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue developmentGO:00098882520.518
regulation of cellular component movementGO:00512701500.241
enzyme linked receptor protein signaling pathwayGO:00071671160.239
response to corticosteroidGO:00319602350.182
anatomical structure morphogenesisGO:00096532980.174
regulation of transporter activityGO:0032409500.155
regulation of rna metabolic processGO:00512523910.151
response to glucocorticoidGO:00513842230.147
organ morphogenesisGO:0009887750.120
cell migrationGO:00164771970.113
positive regulation of response to stimulusGO:00485842850.110
positive regulation of macromolecule biosynthetic processGO:00105572470.100
ion transmembrane transportGO:00342203650.100
apoptotic processGO:00069153810.098
cell motilityGO:00488702020.097
cellular response to lipidGO:00713962010.090
cellular response to alkaloidGO:0071312250.090
regulation of cell migrationGO:00303341280.084
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.082
cellular component movementGO:00069282480.082
sodium ion transportGO:0006814820.082
positive regulation of cell proliferationGO:00082842490.080
transcription from rna polymerase ii promoterGO:00063662520.077
regulation of sodium ion transmembrane transporter activityGO:200064940.076
localization of cellGO:00516742020.076
regulation of signal transductionGO:00099663180.074
regulation of cell proliferationGO:00421273590.073
cell projection organizationGO:00300303020.070
reproductive system developmentGO:00614581280.068
epithelium developmentGO:0060429960.067
regulation of transmembrane transportGO:00347621220.065
l glutamate importGO:005193820.064
neuron developmentGO:00486662860.064
tissue morphogenesisGO:0048729220.064
homeostatic processGO:00425923310.063
regulation of intracellular signal transductionGO:19025312180.061
regulation of apoptotic processGO:00429813350.061
regulation of cell differentiationGO:00455953200.060
cellular metal ion homeostasisGO:00068751720.060
regulation of molecular functionGO:00650093980.060
cellular response to organic cyclic compoundGO:00714072020.059
regulation of cell motilityGO:20001451310.059
neuron deathGO:00709971270.058
development of primary sexual characteristicsGO:00451371070.058
regulation of transmembrane transporter activityGO:0022898490.057
cellular response to endogenous stimulusGO:00714953770.056
locomotionGO:00400112370.054
neuron differentiationGO:00301823680.054
positive regulation of intracellular signal transductionGO:19025331380.054
regulation of programmed cell deathGO:00430673410.053
regulation of transcription from rna polymerase ii promoterGO:00063572340.051
regulation of multicellular organismal developmentGO:20000263760.051
regulation of rna biosynthetic processGO:20011413810.051
central nervous system developmentGO:00074173110.051
regulation of phosphate metabolic processGO:00192203490.051
positive regulation of locomotionGO:00400171020.048
cellular response to steroid hormone stimulusGO:0071383930.048
positive regulation of nucleic acid templated transcriptionGO:19035081970.047
chemical homeostasisGO:00488782920.047
response to extracellular stimulusGO:00099913800.047
nucleic acid templated transcriptionGO:00976593790.047
carbohydrate derivative catabolic processGO:19011361470.046
regulation of establishment of planar polarityGO:009017520.046
response to bacteriumGO:00096172000.046
urogenital system developmentGO:0001655780.046
response to hyperoxiaGO:0055093450.046
response to nutrient levelsGO:00316673700.046
negative regulation of apoptotic processGO:00430661810.045
tube developmentGO:0035295890.045
response to peptideGO:19016522920.045
ossificationGO:0001503700.045
response to cytokineGO:00340972150.044
regulation of transcription dna templatedGO:00063553740.044
regulation of ion transportGO:00432692450.044
positive regulation of nitrogen compound metabolic processGO:00511733340.043
positive regulation of transcription dna templatedGO:00458931970.042
transmembrane transportGO:00550854120.041
regulation of nucleic acid templated transcriptionGO:19035063800.041
cellular response to growth factor stimulusGO:00713631620.041
positive regulation of molecular functionGO:00440932300.041
respiratory system developmentGO:0060541450.040
gland developmentGO:00487321550.040
cardiac muscle cell contractionGO:0086003100.040
positive regulation of programmed cell deathGO:00430681570.040
positive regulation of cellular component movementGO:00512721020.040
cellular lipid metabolic processGO:00442552080.039
actin filament based processGO:0030029860.039
negative regulation of multicellular organismal processGO:00512412030.039
reproductive structure developmentGO:00486081280.039
response to insulinGO:00328681330.039
negative regulation of cell communicationGO:00106481580.038
cellular chemical homeostasisGO:00550822470.038
response to estrogenGO:00436272320.038
response to monosaccharideGO:00342841590.038
behaviorGO:00076102050.037
negative regulation of cellular biosynthetic processGO:00313271610.037
response to acid chemicalGO:00011012220.037
negative regulation of signal transductionGO:0009968830.037
negative regulation of transportGO:00510511360.037
response to external biotic stimulusGO:00432072210.037
positive regulation of developmental processGO:00510942830.037
organophosphate metabolic processGO:00196373700.036
positive regulation of cell migrationGO:0030335960.036
negative regulation of macromolecule biosynthetic processGO:00105581480.036
immune system processGO:00023762040.036
response to oxygen levelsGO:00704822650.036
head developmentGO:00603222470.035
inorganic ion transmembrane transportGO:00986602290.035
negative regulation of nitrogen compound metabolic processGO:00511721610.035
neurological system processGO:00508772190.035
oxoacid metabolic processGO:00434362900.034
inorganic cation transmembrane transportGO:00986622020.034
response to woundingGO:00096112540.034
negative regulation of cell deathGO:00605482290.034
response to ketoneGO:19016541820.034
positive regulation of biosynthetic processGO:00098913190.033
regulation of homeostatic processGO:00328441010.033
rna biosynthetic processGO:00327743800.033
positive regulation of gene expressionGO:00106282440.033
lipid metabolic processGO:00066292830.033
transcription dna templatedGO:00063513770.032
positive regulation of rna biosynthetic processGO:19026801970.032
positive regulation of phosphorus metabolic processGO:00105622620.032
positive regulation of signal transductionGO:00099671750.032
cell part morphogenesisGO:00329901230.032
cellular amino acid metabolic processGO:00065201070.032
developmental process involved in reproductionGO:00030061590.032
regulation of cellular component organizationGO:00511283680.032
cation transmembrane transportGO:00986552630.032
development of primary female sexual characteristicsGO:0046545560.031
kidney developmentGO:0001822670.031
response to peptide hormoneGO:00434342780.031
negative regulation of signalingGO:00230571570.031
axis specificationGO:000979840.031
neuron projection developmentGO:00311752730.031
regulation of ion transmembrane transporter activityGO:0032412480.031
immune responseGO:00069551040.030
purine containing compound catabolic processGO:00725231380.030
multicellular organismal homeostasisGO:0048871490.030
multicellular organism reproductionGO:00325042330.030
organ formationGO:004864530.030
single organism reproductive processGO:00447022970.030
female sex differentiationGO:0046660590.030
anatomical structure formation involved in morphogenesisGO:0048646830.030
regulation of secretionGO:00510462240.029
rna metabolic processGO:00160704060.029
regulation of protein phosphorylationGO:00019321830.029
circulatory system developmentGO:00723591340.029
positive regulation of signalingGO:00230562700.029
regulation of ion transmembrane transportGO:00347651210.029
organic acid metabolic processGO:00060822920.029
positive regulation of cellular biosynthetic processGO:00313282950.029
chemosensory behaviorGO:000763520.028
regulation of secretion by cellGO:19035302080.028
cellular response to nitrogen compoundGO:19016992100.028
regulation of catalytic activityGO:00507903040.028
response to vitaminGO:00332731310.028
reproductionGO:00000032450.028
positive regulation of rna metabolic processGO:00512542030.028
intracellular signal transductionGO:00355563140.028
programmed cell deathGO:00125013920.028
alcohol metabolic processGO:0006066770.028
regulation of phosphorylationGO:00423252480.027
regulation of protein modification processGO:00313991940.027
cellular component morphogenesisGO:00329891550.027
positive regulation of cell motilityGO:2000147970.027
cellular response to reactive oxygen speciesGO:0034614550.027
organic substance catabolic processGO:19015753160.026
cellular response to oxygen containing compoundGO:19017013860.026
morphogenesis of an epitheliumGO:0002009200.026
cytosolic calcium ion homeostasisGO:00514801400.026
response to hexoseGO:00097461440.026
regulation of metal ion transportGO:00109591180.026
negative regulation of biosynthetic processGO:00098901680.026
negative regulation of molecular functionGO:00440921330.026
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.025
positive regulation of ion transmembrane transporter activityGO:0032414130.025
single organism catabolic processGO:00447122830.025
regulation of locomotionGO:00400121480.025
response to estradiolGO:00323551640.025
eye morphogenesisGO:004859240.025
regulation of protein metabolic processGO:00512462890.025
amine metabolic processGO:0009308380.025
response to growth factorGO:00708481890.025
biological adhesionGO:00226101100.025
regulation of hormone levelsGO:00108171870.024
positive regulation of phosphorylationGO:00423271770.024
negative regulation of metabolic processGO:00098923310.024
negative regulation of rna biosynthetic processGO:19026791180.024
gonad developmentGO:00084061040.024
negative regulation of ion transportGO:0043271510.024
establishment of tissue polarityGO:000716420.024
cellular component biogenesisGO:00440853680.023
carbohydrate derivative metabolic processGO:19011353460.023
regulation of cation channel activityGO:2001257230.023
positive regulation of cell differentiationGO:00455972170.023
metal ion transportGO:00300012890.023
regenerationGO:00310991630.023
cellular homeostasisGO:00197252520.023
regulation of cell developmentGO:00602842630.022
monovalent inorganic cation transportGO:00156721720.022
catabolic processGO:00090563510.022
cellular amine metabolic processGO:0044106380.022
positive regulation of cellular component organizationGO:00511302000.022
response to retinoic acidGO:0032526630.022
negative regulation of programmed cell deathGO:00430691830.022
positive regulation of cell communicationGO:00106472710.022
negative regulation of gene expressionGO:00106291990.022
ion homeostasisGO:00508012120.021
bone developmentGO:0060348250.021
positive regulation of apoptotic processGO:00430651540.021
cell morphogenesisGO:00009021420.021
response to molecule of bacterial originGO:00022371940.021
reproductive processGO:00224143720.021
positive regulation of transportGO:00510502450.021
cellular amide metabolic processGO:0043603440.021
hormone secretionGO:00468791150.021
positive regulation of smooth muscle cell proliferationGO:0048661510.020
heart morphogenesisGO:000300730.020
agingGO:00075682410.020
organic hydroxy compound metabolic processGO:19016151150.020
cellular response to hormone stimulusGO:00328702470.020
macromolecule localizationGO:00330362520.020
response to oxidative stressGO:00069791860.020
cellular catabolic processGO:00442482950.020
hematopoietic progenitor cell differentiationGO:000224420.020
cellular response to stressGO:00335542690.020
angiogenesisGO:0001525530.020
epithelial cell differentiationGO:0030855710.020
purine containing compound metabolic processGO:00725212530.020
forebrain developmentGO:0030900980.020
secretionGO:00469033070.020
cellular calcium ion homeostasisGO:00068741600.020
ribose phosphate metabolic processGO:00196932350.020
cellular ion homeostasisGO:00068731840.019
lung developmentGO:0030324430.019
protein complex subunit organizationGO:00718223020.019
coronary vasculature morphogenesisGO:006097730.019
glycosyl compound metabolic processGO:19016571820.019
regulation of system processGO:00440572080.019
single organismal cell cell adhesionGO:0016337420.019
ribonucleotide catabolic processGO:00092611360.019
metal ion homeostasisGO:00550651860.019
adult locomotory behaviorGO:000834440.019
sensory perceptionGO:00076001010.018
sensory organ developmentGO:0007423740.018
cellular response to nicotineGO:007131670.018
macromolecular complex subunit organizationGO:00439333390.018
cation transportGO:00068123820.018
regulation of ion homeostasisGO:2000021630.018
regulation of cellular protein metabolic processGO:00322682670.018
divalent inorganic cation homeostasisGO:00725071650.018
calcium ion homeostasisGO:00550741620.018
renal system developmentGO:0072001670.018
protein localizationGO:00081041910.018
male gonad developmentGO:0008584590.018
palate developmentGO:006002120.018
regulation of fat cell differentiationGO:004559830.018
secretion by cellGO:00329402480.018
multicellular organismal reproductive processGO:00486092330.018
response to other organismGO:00517072200.018
development of primary male sexual characteristicsGO:0046546590.017
ribonucleotide metabolic processGO:00092592310.017
cellular response to oxidative stressGO:0034599760.017
olfactory behaviorGO:004204820.017
regulation of cell projection organizationGO:00313441750.017
positive regulation of cellular protein metabolic processGO:00322701670.017
regulation of smooth muscle cell proliferationGO:0048660750.017
regulation of epithelial cell proliferationGO:0050678490.017
membrane depolarization during cardiac muscle cell action potentialGO:008601210.017
purine ribonucleoside monophosphate metabolic processGO:0009167840.017
vasculature developmentGO:0001944700.017
negative regulation of macromolecule metabolic processGO:00106052600.017
response to tumor necrosis factorGO:0034612560.017
regulation of phosphorus metabolic processGO:00511743490.017
s shaped body morphogenesisGO:007205020.017
female gonad developmentGO:0008585530.017
cardiovascular system developmentGO:00723581340.017
retina morphogenesis in camera type eyeGO:006004210.017
positive regulation of phosphate metabolic processGO:00459372620.016
single organism biosynthetic processGO:00447113420.016
muscle tissue developmentGO:0060537580.016
organic cyclic compound catabolic processGO:19013611750.016
positive regulation of neurogenesisGO:00507691650.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
cellular cation homeostasisGO:00300031800.016
brain developmentGO:00074202470.016
cellular response to mechanical stimulusGO:0071260480.016
response to reactive oxygen speciesGO:00003021200.016
organophosphate catabolic processGO:00464341480.016
positive regulation of kinase activityGO:0033674770.016
salivary gland developmentGO:000743130.015
organelle organizationGO:00069962660.015
response to purine containing compoundGO:00140741260.015
negative regulation of rna metabolic processGO:00512531230.015
purine nucleotide catabolic processGO:00061951360.015
regulation of neuron apoptotic processGO:0043523830.015
cellular response to cytokine stimulusGO:00713451270.015
morphogenesis of a polarized epitheliumGO:000173810.015
skeletal system developmentGO:0001501410.015
regulation of protein transportGO:0051223680.015
positive regulation of protein modification processGO:00314011420.015
positive regulation of multicellular organismal processGO:00512403870.015
developmental growthGO:00485891000.015
protein complex biogenesisGO:00702712630.015
response to increased oxygen levelsGO:0036296450.015
endocrine system developmentGO:0035270300.015
response to glucoseGO:00097491360.015
regulation of hydrolase activityGO:00513361430.015
positive regulation of catalytic activityGO:00430851840.015
purine nucleoside metabolic processGO:00422781690.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
purine nucleotide metabolic processGO:00061632290.015
cellular ketone metabolic processGO:0042180510.015
negative regulation of transcription dna templatedGO:00458921160.015
regulation of cellular localizationGO:00603412630.015
cytoskeleton organizationGO:00070101110.015
rhythmic processGO:00485111560.015
regulation of cellular amino acid metabolic processGO:000652120.015
negative regulation of cellular metabolic processGO:00313242810.014
sodium ion transmembrane transportGO:0035725670.014
wnt signaling pathway planar cell polarity pathwayGO:006007120.014
regulation of transferase activityGO:00513381230.014
embryonic pattern specificationGO:000988010.014
cellular response to external stimulusGO:00714961180.014
regulation of neurogenesisGO:00507672470.014
intracellular transportGO:00469071850.014
positive regulation of protein metabolic processGO:00512471780.014
cellular nitrogen compound catabolic processGO:00442701630.014
leukocyte migrationGO:0050900380.014
anion transportGO:00068201780.014
angiogenesis involved in coronary vascular morphogenesisGO:006097830.014
hematopoietic or lymphoid organ developmentGO:0048534360.014
ribonucleoside metabolic processGO:00091191740.014
divalent metal ion transportGO:00708381320.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
immune system developmentGO:0002520410.014
response to lipopolysaccharideGO:00324961910.013
cardiac muscle contractionGO:0060048270.013
respiratory tube developmentGO:0030323430.013
regulation of sodium ion transportGO:0002028210.013
nucleoside metabolic processGO:00091161790.013
growthGO:00400071650.013
nerve developmentGO:0021675110.013
entrainment of circadian clockGO:000964930.013
carbohydrate metabolic processGO:00059751300.013
bmp signaling pathwayGO:003050940.013
protein transportGO:00150311320.013
positive regulation of protein serine threonine kinase activityGO:0071902520.013
single organism organelle organizationGO:19025891800.013
small gtpase mediated signal transductionGO:0007264360.013
establishment of planar polarityGO:000173610.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
sensory perception of light stimulusGO:005095330.013
negative regulation of developmental processGO:00510931250.013
cell cell signaling involved in cell fate commitmentGO:004516820.013
positive regulation of potassium ion transportGO:0043268130.013
cellular response to organonitrogen compoundGO:00714171970.012
response to decreased oxygen levelsGO:00362932370.012
organ inductionGO:000175910.012
nucleobase containing compound catabolic processGO:00346551520.012
muscle system processGO:00030121150.012
cellular component assemblyGO:00226073600.012
taxisGO:0042330670.012
lens fiber cell differentiationGO:007030630.012
cellular response to peptideGO:19016531330.012
response to fibroblast growth factorGO:0071774290.012
cell differentiation involved in kidney developmentGO:006100540.012
carboxylic acid transportGO:00469421150.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
response to hydrogen peroxideGO:0042542890.012
regulation of kinase activityGO:00435491170.012
response to testosteroneGO:0033574550.012
oxidation reduction processGO:00551143040.012
regulation of cellular ketone metabolic processGO:0010565270.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
cell projection morphogenesisGO:00488581230.012
single organism cellular localizationGO:19025801020.011
cellular response to abiotic stimulusGO:0071214850.011
metestrusGO:006021010.011
gamete generationGO:00072761240.011
single organism carbohydrate metabolic processGO:00447231180.011
muscle structure developmentGO:0061061870.011
response to biotic stimulusGO:00096072260.011
maintenance of locationGO:0051235170.011
negative regulation of cellular protein metabolic processGO:00322691060.011
camera type eye developmentGO:0043010480.011
camera type eye morphogenesisGO:004859320.011
metanephric s shaped body morphogenesisGO:007228420.011
striated muscle tissue developmentGO:0014706580.011
insulin secretionGO:0030073690.011
positive regulation of cell projection organizationGO:00313461110.011
response to blue lightGO:000963710.011
positive regulation of growthGO:0045927550.011
muscle contractionGO:0006936880.011
cell growthGO:00160491040.011
anterior posterior pattern specificationGO:000995210.010
lipid storageGO:001991510.010
cell activationGO:0001775970.010
specification of organ identityGO:001009220.010
regulation of peptide hormone secretionGO:0090276800.010
cation homeostasisGO:00550801950.010
cell cycle checkpointGO:000007520.010
muscle cell proliferationGO:0033002840.010
wound healingGO:00420601220.010
circadian rhythmGO:0007623880.010
positive regulation of cell developmentGO:00107201760.010
sex differentiationGO:00075481130.010
cytoplasmic transportGO:00164821150.010
negative regulation of canonical wnt signaling pathwayGO:009009040.010
regulation of intracellular transportGO:0032386650.010
phospholipid metabolic processGO:0006644610.010

Irx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinal diseaseDOID:567900.083
retinal degenerationDOID:846600.083
sensory system diseaseDOID:005015500.083
eye and adnexa diseaseDOID:149200.083
eye diseaseDOID:561400.083
disease of anatomical entityDOID:700.083
retinitis pigmentosaDOID:1058400.083
nervous system diseaseDOID:86300.083
musculoskeletal system diseaseDOID:1700.032
connective tissue diseaseDOID:6500.018
cardiovascular system diseaseDOID:128700.018
heart diseaseDOID:11400.018
bone diseaseDOID:008000100.015
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.013
myopathyDOID:42300.013
bone development diseaseDOID:008000600.012