Rattus norvegicus

58 known processes

Igf2r

insulin-like growth factor 2 receptor

Igf2r biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.320
organelle organizationGO:00069962660.294
cell projection organizationGO:00300303020.255
neuron projection developmentGO:00311752730.233
oxoacid metabolic processGO:00434362900.218
regulation of cell developmentGO:00602842630.210
cell morphogenesis involved in neuron differentiationGO:00486671060.201
cellular component movementGO:00069282480.199
regulation of neurogenesisGO:00507672470.195
regulation of cell differentiationGO:00455953200.193
regulation of multicellular organismal developmentGO:20000263760.182
biological adhesionGO:00226101100.175
cell migrationGO:00164771970.163
regulation of cellular component organizationGO:00511283680.156
anatomical structure morphogenesisGO:00096532980.146
carboxylic acid metabolic processGO:00197522890.144
single organism membrane organizationGO:0044802740.144
regulation of cellular component movementGO:00512701500.142
neuron developmentGO:00486662860.142
regulation of transcription dna templatedGO:00063553740.140
cell part morphogenesisGO:00329901230.140
regulation of nervous system developmentGO:00519602640.139
neuron projection morphogenesisGO:00488121220.135
membrane organizationGO:0061024940.134
regulation of phosphorus metabolic processGO:00511743490.134
intracellular signal transductionGO:00355563140.133
regulation of cell morphogenesis involved in differentiationGO:0010769720.131
cell morphogenesis involved in differentiationGO:00009041190.131
regulation of rna biosynthetic processGO:20011413810.130
regulation of cellular protein metabolic processGO:00322682670.129
response to decreased oxygen levelsGO:00362932370.128
positive regulation of cellular component organizationGO:00511302000.128
apoptotic processGO:00069153810.126
regulation of nucleic acid templated transcriptionGO:19035063800.125
taxisGO:0042330670.121
response to nutrient levelsGO:00316673700.120
macromolecular complex subunit organizationGO:00439333390.117
regulation of neuron differentiationGO:00456642080.116
cellular component biogenesisGO:00440853680.115
positive regulation of phosphorus metabolic processGO:00105622620.111
macromolecular complex assemblyGO:00650032730.110
enzyme linked receptor protein signaling pathwayGO:00071671160.103
cell projection morphogenesisGO:00488581230.102
single organism biosynthetic processGO:00447113420.101
positive regulation of developmental processGO:00510942830.097
cellular response to endogenous stimulusGO:00714953770.097
regulation of locomotionGO:00400121480.097
cellular component morphogenesisGO:00329891550.096
regulation of cell migrationGO:00303341280.096
localization of cellGO:00516742020.094
reproductive processGO:00224143720.094
response to metal ionGO:00100382530.093
regulation of phosphorylationGO:00423252480.093
protein complex subunit organizationGO:00718223020.093
organic acid metabolic processGO:00060822920.093
cellular component assemblyGO:00226073600.092
response to nutrientGO:00075842480.092
regulation of phosphate metabolic processGO:00192203490.091
positive regulation of cellular biosynthetic processGO:00313282950.089
oxidation reduction processGO:00551143040.088
tissue developmentGO:00098882520.088
programmed cell deathGO:00125013920.086
positive regulation of nervous system developmentGO:00519621780.085
response to oxygen levelsGO:00704822650.084
chemotaxisGO:0006935660.084
response to extracellular stimulusGO:00099913800.083
regulation of molecular functionGO:00650093980.082
growthGO:00400071650.082
macromolecule localizationGO:00330362520.081
positive regulation of phosphorylationGO:00423271770.080
regulation of apoptotic processGO:00429813350.080
negative regulation of cell developmentGO:0010721820.078
negative regulation of metabolic processGO:00098923310.078
response to transforming growth factor betaGO:0071559460.078
negative regulation of cellular component organizationGO:0051129830.076
positive regulation of nitrogen compound metabolic processGO:00511733340.075
axonogenesisGO:0007409710.075
positive regulation of multicellular organismal processGO:00512403870.075
protein complex assemblyGO:00064612630.075
regulation of cell motilityGO:20001451310.073
regulation of protein modification processGO:00313991940.072
positive regulation of cell developmentGO:00107201760.072
positive regulation of cell differentiationGO:00455972170.071
regulation of neuron projection developmentGO:00109751610.071
protein phosphorylationGO:00064683450.071
response to peptide hormoneGO:00434342780.067
regulation of catalytic activityGO:00507903040.067
motor neuron axon guidanceGO:000804510.067
epithelium developmentGO:0060429960.067
cell motilityGO:00488702020.067
secretionGO:00469033070.067
cellular response to peptide hormone stimulusGO:00713751200.066
negative regulation of nervous system developmentGO:0051961790.066
cellular response to growth factor stimulusGO:00713631620.066
cellular response to oxygen containing compoundGO:19017013860.066
protein complex biogenesisGO:00702712630.065
response to estrogenGO:00436272320.065
positive regulation of phosphate metabolic processGO:00459372620.065
central nervous system developmentGO:00074173110.065
positive regulation of neurogenesisGO:00507691650.064
response to growth factorGO:00708481890.064
positive regulation of cell motilityGO:2000147970.064
cell growthGO:00160491040.064
positive regulation of biosynthetic processGO:00098913190.063
negative regulation of multicellular organismal processGO:00512412030.063
regulation of protein phosphorylationGO:00019321830.062
single organism organelle organizationGO:19025891800.062
single organism cellular localizationGO:19025801020.061
developmental process involved in reproductionGO:00030061590.061
positive regulation of signalingGO:00230562700.060
response to hypoxiaGO:00016662310.060
regulation of cellular ketone metabolic processGO:0010565270.059
positive regulation of cellular component movementGO:00512721020.059
negative regulation of biosynthetic processGO:00098901680.059
response to inorganic substanceGO:00100353770.058
response to peptideGO:19016522920.058
hepaticobiliary system developmentGO:0061008900.057
cation homeostasisGO:00550801950.057
axon developmentGO:0061564960.057
cellular response to stressGO:00335542690.057
regulation of protein metabolic processGO:00512462890.056
positive regulation of transcription dna templatedGO:00458931970.055
cellular ketone metabolic processGO:0042180510.054
regulation of response to external stimulusGO:00321011060.054
skeletal system developmentGO:0001501410.054
neuron projection guidanceGO:0097485240.054
transcription dna templatedGO:00063513770.054
cell morphogenesisGO:00009021420.053
regulation of growthGO:00400081050.053
negative regulation of neurogenesisGO:0050768780.053
positive regulation of catalytic activityGO:00430851840.052
regulation of canonical wnt signaling pathwayGO:006082840.052
positive regulation of cell proliferationGO:00082842490.052
regulation of cell proliferationGO:00421273590.050
regulation of cell projection organizationGO:00313441750.050
cell substrate adhesionGO:0031589290.050
cell adhesionGO:00071551100.049
brain developmentGO:00074202470.049
regulation of intracellular signal transductionGO:19025312180.049
negative regulation of cell differentiationGO:0045596990.049
negative regulation of cellular metabolic processGO:00313242810.048
rna biosynthetic processGO:00327743800.048
anion transmembrane transportGO:0098656770.048
positive regulation of response to stimulusGO:00485842850.048
negative regulation of cell proliferationGO:00082851190.048
regulation of cellular localizationGO:00603412630.048
positive regulation of molecular functionGO:00440932300.048
negative regulation of neuron differentiationGO:0045665620.048
response to oxidative stressGO:00069791860.047
peptidyl amino acid modificationGO:00181931260.047
regulation of signal transductionGO:00099663180.047
gastrulationGO:000736920.047
head developmentGO:00603222470.047
ion transmembrane transportGO:00342203650.047
regenerationGO:00310991630.047
purine ribonucleotide metabolic processGO:00091502270.047
appendage morphogenesisGO:003510740.046
locomotionGO:00400112370.046
endomembrane system organizationGO:0010256480.045
cellular response to organonitrogen compoundGO:00714171970.045
positive regulation of apoptotic processGO:00430651540.045
positive regulation of cellular protein metabolic processGO:00322701670.045
cellular homeostasisGO:00197252520.044
response to toxic substanceGO:00096361330.044
secretion by cellGO:00329402480.044
cellular chemical homeostasisGO:00550822470.043
positive regulation of gene expressionGO:00106282440.042
protein transportGO:00150311320.042
mesoderm developmentGO:000749820.042
negative regulation of cell communicationGO:00106481580.042
response to insulinGO:00328681330.042
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.042
positive regulation of rna biosynthetic processGO:19026801970.042
ossificationGO:0001503700.042
nucleic acid templated transcriptionGO:00976593790.042
transmembrane transportGO:00550854120.041
digestive system developmentGO:0055123410.041
vesicle mediated transportGO:00161921810.041
positive regulation of transportGO:00510502450.041
cellular macromolecule localizationGO:00707271220.040
mechanoreceptor differentiationGO:004249020.040
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.040
reproductionGO:00000032450.040
anatomical structure formation involved in morphogenesisGO:0048646830.040
response to estradiolGO:00323551640.040
dendrite morphogenesisGO:0048813430.040
multicellular organism reproductionGO:00325042330.039
negative regulation of nitrogen compound metabolic processGO:00511721610.039
establishment of protein localizationGO:00451841410.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.039
single organism catabolic processGO:00447122830.039
circulatory system developmentGO:00723591340.039
negative regulation of cell deathGO:00605482290.039
regulation of cell growthGO:0001558850.038
cytoplasmic transportGO:00164821150.038
multi organism reproductive processGO:00447032620.038
hair cell differentiationGO:003531520.038
anterior posterior pattern specificationGO:000995210.038
intracellular transportGO:00469071850.037
catabolic processGO:00090563510.037
liver developmentGO:0001889900.037
negative regulation of developmental processGO:00510931250.037
lipid biosynthetic processGO:00086101280.037
positive regulation of cell projection organizationGO:00313461110.037
protein localizationGO:00081041910.037
nucleoside monophosphate metabolic processGO:0009123930.036
synaptic growth at neuromuscular junctionGO:005112410.036
blood circulationGO:00080151830.036
positive regulation of signal transductionGO:00099671750.036
circulatory system processGO:00030131830.036
positive regulation of locomotionGO:00400171020.036
cellular response to peptideGO:19016531330.036
cellular response to nitrogen compoundGO:19016992100.035
homeostatic processGO:00425923310.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
transcription from rna polymerase ii promoterGO:00063662520.035
positive regulation of cell migrationGO:0030335960.035
immune system processGO:00023762040.035
negative regulation of macromolecule metabolic processGO:00106052600.035
regulation of anatomical structure sizeGO:00900661350.035
cellular amino acid metabolic processGO:00065201070.035
negative regulation of cellular biosynthetic processGO:00313271610.035
bmp signaling pathwayGO:003050940.035
limb morphogenesisGO:003510840.035
single organism intracellular transportGO:19025821660.034
cellular response to transforming growth factor beta stimulusGO:0071560410.034
carbohydrate derivative metabolic processGO:19011353460.034
dna metabolic processGO:0006259960.034
regulation of system processGO:00440572080.034
positive regulation of intracellular signal transductionGO:19025331380.034
positive regulation of cell communicationGO:00106472710.033
wound healingGO:00420601220.033
protein heterooligomerizationGO:0051291890.033
regulation of protein kinase activityGO:00458591050.033
gland developmentGO:00487321550.032
bone developmentGO:0060348250.032
negative regulation of gene expressionGO:00106291990.032
embryonic appendage morphogenesisGO:003511340.032
synapse organizationGO:0050808460.032
single organism reproductive processGO:00447022970.032
intracellular protein transportGO:0006886790.032
dendrite developmentGO:0016358720.032
rna metabolic processGO:00160704060.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.032
urogenital system developmentGO:0001655780.032
purine containing compound metabolic processGO:00725212530.032
non canonical wnt signaling pathwayGO:003556730.031
positive regulation of protein phosphorylationGO:00019341350.031
vasculogenesisGO:000157030.031
negative regulation of response to stimulusGO:00485851550.031
inorganic ion transmembrane transportGO:00986602290.031
cellular response to hormone stimulusGO:00328702470.031
response to corticosteroidGO:00319602350.031
cellular amine metabolic processGO:0044106380.030
blood vessel developmentGO:0001568690.030
positive regulation of rna metabolic processGO:00512542030.030
regulation of secretionGO:00510462240.030
negative regulation of apoptotic processGO:00430661810.030
regulation of response to stressGO:00801341260.030
glutathione transportGO:003463520.030
positive regulation of mapk cascadeGO:0043410920.030
positive regulation of programmed cell deathGO:00430681570.030
cellular protein localizationGO:00346131220.030
transforming growth factor beta receptor signaling pathwayGO:0007179180.030
embryo developmentGO:0009790490.030
regulation of cellular amino acid metabolic processGO:000652120.030
negative regulation of programmed cell deathGO:00430691830.030
auditory receptor cell differentiationGO:004249120.030
tube developmentGO:0035295890.029
ion homeostasisGO:00508012120.029
heart morphogenesisGO:000300730.029
regulation of establishment of planar polarityGO:009017520.029
organophosphate metabolic processGO:00196373700.029
proteolysisGO:00065081750.029
cation transmembrane transportGO:00986552630.029
regulation of transferase activityGO:00513381230.028
multicellular organism growthGO:003526410.028
cation transportGO:00068123820.028
cellular response to external stimulusGO:00714961180.028
response to starvationGO:0042594590.028
kidney developmentGO:0001822670.028
positive regulation of neuron projection developmentGO:0010976990.027
regulation of cell morphogenesisGO:0022604770.027
carbohydrate metabolic processGO:00059751300.027
regulation of neuron deathGO:19012141150.027
organic substance catabolic processGO:19015753160.027
lipid metabolic processGO:00066292830.027
neuron apoptotic processGO:0051402880.027
negative regulation of molecular functionGO:00440921330.027
mapk cascadeGO:00001651400.027
eye developmentGO:0001654500.027
positive regulation of cell deathGO:00109421840.027
ribonucleotide metabolic processGO:00092592310.026
positive regulation of cellular amino acid metabolic processGO:004576410.026
chemical homeostasisGO:00488782920.026
nucleoside phosphate metabolic processGO:00067532830.026
response to vitaminGO:00332731310.026
defense responseGO:00069521940.026
regulation of anatomical structure morphogenesisGO:00226031410.026
regulation of chemotaxisGO:0050920290.026
developmental growthGO:00485891000.026
regulation of kinase activityGO:00435491170.026
purine nucleoside triphosphate metabolic processGO:00091441410.026
ribose phosphate metabolic processGO:00196932350.026
positive regulation of cellular amine metabolic processGO:003324030.026
signal transduction by phosphorylationGO:00230141440.026
neurological system processGO:00508772190.026
inner ear receptor cell differentiationGO:006011320.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.026
nucleobase containing small molecule metabolic processGO:00550863160.026
protein localization to membraneGO:0072657360.026
rhythmic processGO:00485111560.026
protein oligomerizationGO:00512591910.025
small molecule biosynthetic processGO:00442831240.025
positive regulation of protein modification processGO:00314011420.025
negative regulation of rna metabolic processGO:00512531230.025
regulation of membrane potentialGO:00423911100.025
regulation of cellular component biogenesisGO:0044087860.025
reproductive structure developmentGO:00486081280.025
embryonic pattern specificationGO:000988010.025
cell type specific apoptotic processGO:00972851340.025
regulation of vesicle mediated transportGO:0060627810.025
regulation of programmed cell deathGO:00430673410.025
organophosphate catabolic processGO:00464341480.025
gamete generationGO:00072761240.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.024
behaviorGO:00076102050.024
cellular ion homeostasisGO:00068731840.024
lipid localizationGO:0010876620.024
negative regulation of cellular protein metabolic processGO:00322691060.024
negative regulation of cell cycle g1 s phase transitionGO:190280720.024
organonitrogen compound biosynthetic processGO:19015661670.024
regulation of cellular amine metabolic processGO:003323880.024
neuron deathGO:00709971270.024
hindlimb morphogenesisGO:003513720.024
response to bacteriumGO:00096172000.024
glycosaminoglycan biosynthetic processGO:000602440.024
negative regulation of signalingGO:00230571570.024
metal ion homeostasisGO:00550651860.024
g protein coupled receptor signaling pathwayGO:00071862420.023
response to woundingGO:00096112540.023
development of primary sexual characteristicsGO:00451371070.023
cellular response to insulin stimulusGO:0032869810.023
carbohydrate derivative biosynthetic processGO:19011371240.023
negative regulation of signal transductionGO:0009968830.023
synaptic transmissionGO:00072682350.023
carboxylic acid transportGO:00469421150.023
monocarboxylic acid metabolic processGO:00327871520.023
nucleotide metabolic processGO:00091172790.022
sexual reproductionGO:00199531480.022
aromatic compound catabolic processGO:00194391680.022
cellular cation homeostasisGO:00300031800.022
purine nucleotide metabolic processGO:00061632290.022
small gtpase mediated signal transductionGO:0007264360.022
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.022
cellular catabolic processGO:00442482950.022
cell cell signalingGO:00072673350.022
lipid transportGO:0006869610.022
glycosyl compound metabolic processGO:19016571820.022
negative regulation of protein metabolic processGO:00512481140.022
response to carbohydrateGO:00097431830.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
amine metabolic processGO:0009308380.022
ribonucleoside metabolic processGO:00091191740.022
action potentialGO:0001508540.022
eye morphogenesisGO:004859240.022
axon guidanceGO:0007411240.022
alcohol metabolic processGO:0006066770.022
regulation of protein localizationGO:0032880810.021
cytoskeleton organizationGO:00070101110.021
regulation of cellular response to stressGO:0080135490.021
epithelial cell differentiationGO:0030855710.021
protein targetingGO:0006605610.021
organ formationGO:004864530.021
gliogenesisGO:0042063930.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.021
nucleoside metabolic processGO:00091161790.021
response to acid chemicalGO:00011012220.021
forebrain developmentGO:0030900980.021
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.020
skin morphogenesisGO:004358920.020
response to lipopolysaccharideGO:00324961910.020
response to reactive oxygen speciesGO:00003021200.020
organ morphogenesisGO:0009887750.020
cellular metal ion homeostasisGO:00068751720.020
cardiac chamber developmentGO:000320510.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
positive regulation of hydrolase activityGO:0051345860.020
positive regulation of neuron differentiationGO:00456661260.020
positive regulation of protein metabolic processGO:00512471780.020
inorganic cation transmembrane transportGO:00986622020.020
cellular modified amino acid metabolic processGO:0006575610.019
response to biotic stimulusGO:00096072260.019
sensory organ developmentGO:0007423740.019
calcium ion homeostasisGO:00550741620.019
fatty acid metabolic processGO:0006631990.019
reproductive system developmentGO:00614581280.019
regulation of mapk cascadeGO:00434081160.019
response to glucocorticoidGO:00513842230.019
multicellular organismal signalingGO:0035637440.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
cardiovascular system developmentGO:00723581340.019
cell cycle processGO:0022402570.019
regulation of hormone levelsGO:00108171870.019
transmission of nerve impulseGO:0019226420.019
anion transportGO:00068201780.019
cellular response to organic cyclic compoundGO:00714072020.019
single organism cell adhesionGO:0098602460.019
response to mechanical stimulusGO:00096121340.019
response to calcium ionGO:0051592590.019
divalent inorganic cation transportGO:00725111340.019
actin filament based processGO:0030029860.019
multicellular organismal reproductive processGO:00486092330.019
single organism carbohydrate metabolic processGO:00447231180.019
polysaccharide metabolic processGO:0005976250.019
nucleoside phosphate biosynthetic processGO:19012931020.018
regulation of ion transportGO:00432692450.018
purine ribonucleoside catabolic processGO:00461301240.018
salivary gland morphogenesisGO:000743510.018
neuronal action potentialGO:0019228350.018
response to transition metal nanoparticleGO:19902671220.018
regulation of rna metabolic processGO:00512523910.018
regulation of stem cell differentiationGO:200073620.018
regulation of hydrolase activityGO:00513361430.018
regulation of cell substrate adhesionGO:0010810180.018
purine ribonucleoside metabolic processGO:00461281680.018
male sex differentiationGO:0046661640.018
axis specificationGO:000979840.018
organic hydroxy compound metabolic processGO:19016151150.017
regulation of bmp signaling pathwayGO:003051020.017
cell cycleGO:00070491010.017
cellular response to lipidGO:00713962010.017
metal ion transportGO:00300012890.017
salivary gland developmentGO:000743130.017
regulation of cell adhesionGO:0030155520.017
regulation of secretion by cellGO:19035302080.017
defense response to gram negative bacteriumGO:005082930.017
negative regulation of protein phosphorylationGO:0001933440.017
negative regulation of rna biosynthetic processGO:19026791180.017
reactive oxygen species metabolic processGO:0072593370.017
ribonucleotide biosynthetic processGO:0009260850.017
epithelial cell proliferationGO:0050673540.017
response to alkaloidGO:00432791320.017
vasculature developmentGO:0001944700.017
mitotic spindle organizationGO:000705220.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
negative regulation of phosphate metabolic processGO:0045936800.016
response to amino acidGO:0043200750.016
purine nucleoside monophosphate metabolic processGO:0009126840.016
actin cytoskeleton organizationGO:0030036730.016
cellular nitrogen compound catabolic processGO:00442701630.016
cellular lipid metabolic processGO:00442552080.016
digestive tract developmentGO:0048565390.016
nucleobase containing compound catabolic processGO:00346551520.016
endocytosisGO:0006897840.016
protein processingGO:0016485680.016
ribonucleoside catabolic processGO:00424541260.016
response to ketoneGO:19016541820.016
protein homooligomerizationGO:0051260910.016
oligopeptide transportGO:000685740.016
sex differentiationGO:00075481130.016
divalent inorganic cation homeostasisGO:00725071650.016
positive regulation of transferase activityGO:0051347810.016
regulation of ossificationGO:0030278320.016
regulation of synaptic transmissionGO:00508041410.016
cellular calcium ion homeostasisGO:00068741600.016
sequestering of calcium ionGO:005120880.016
glycosyl compound catabolic processGO:19016581260.016
carbohydrate derivative catabolic processGO:19011361470.016
ras protein signal transductionGO:0007265290.016
purine ribonucleotide biosynthetic processGO:0009152810.016
gonad developmentGO:00084061040.016
embryonic hindlimb morphogenesisGO:003511620.016
response to purine containing compoundGO:00140741260.016
epidermis developmentGO:0008544110.016
regulation of axonogenesisGO:0050770370.016
regulation of wnt signaling pathwayGO:003011180.016
cytosolic calcium ion homeostasisGO:00514801400.015
dephosphorylationGO:0016311980.015
organic acid transportGO:00158491160.015
angiogenesisGO:0001525530.015
organic cyclic compound catabolic processGO:19013611750.015
regulation of blood circulationGO:19035221100.015
regulation of nucleotide metabolic processGO:00061401170.015

Igf2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.187
musculoskeletal system diseaseDOID:1700.187
nervous system diseaseDOID:86300.026
muscular diseaseDOID:008000000.024
connective tissue diseaseDOID:6500.024
disease of metabolismDOID:001466700.019
cardiovascular system diseaseDOID:128700.017
heart diseaseDOID:11400.017
bone diseaseDOID:008000100.015