Rattus norvegicus

0 known processes

Irx1

iroquois homeobox 1

Irx1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to oxygen containing compoundGO:19017013860.230
cellular response to endogenous stimulusGO:00714953770.146
regulation of molecular functionGO:00650093980.140
establishment of organ orientationGO:004856110.136
Rat
lipid metabolic processGO:00066292830.131
regulation of cell proliferationGO:00421273590.129
reproductionGO:00000032450.117
cellular chemical homeostasisGO:00550822470.113
response to nutrient levelsGO:00316673700.113
response to woundingGO:00096112540.109
positive regulation of cell proliferationGO:00082842490.108
response to extracellular stimulusGO:00099913800.102
response to nutrientGO:00075842480.099
cellular response to hormone stimulusGO:00328702470.096
regulation of secretionGO:00510462240.096
programmed cell deathGO:00125013920.095
cellular response to stressGO:00335542690.093
reproductive processGO:00224143720.089
agingGO:00075682410.089
cation transportGO:00068123820.089
multi multicellular organism processGO:00447061380.088
intracellular signal transductionGO:00355563140.087
establishment of protein localizationGO:00451841410.086
establishment of anatomical structure orientationGO:004856010.086
Rat
response to peptide hormoneGO:00434342780.085
homeostatic processGO:00425923310.085
cellular response to nitrogen compoundGO:19016992100.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.078
response to decreased oxygen levelsGO:00362932370.077
endocytosisGO:0006897840.077
response to nicotineGO:0035094510.075
regulation of nucleic acid templated transcriptionGO:19035063800.073
organic hydroxy compound metabolic processGO:19016151150.072
response to oxygen levelsGO:00704822650.071
response to estradiolGO:00323551640.070
protein complex biogenesisGO:00702712630.069
inorganic ion transmembrane transportGO:00986602290.067
cell cell signalingGO:00072673350.066
secretionGO:00469033070.065
cellular component movementGO:00069282480.065
positive regulation of transportGO:00510502450.064
positive regulation of cell communicationGO:00106472710.063
lipid biosynthetic processGO:00086101280.063
multi organism reproductive processGO:00447032620.060
regulation of cellular component organizationGO:00511283680.059
acid secretionGO:0046717480.058
response to hypoxiaGO:00016662310.057
neurological system processGO:00508772190.055
response to carbohydrateGO:00097431830.054
regulation of multicellular organismal developmentGO:20000263760.053
head developmentGO:00603222470.051
apoptotic processGO:00069153810.049
positive regulation of cell deathGO:00109421840.049
response to hexoseGO:00097461440.048
regulation of cell differentiationGO:00455953200.047
positive regulation of apoptotic processGO:00430651540.047
nucleic acid templated transcriptionGO:00976593790.047
positive regulation of signalingGO:00230562700.047
regulation of programmed cell deathGO:00430673410.046
response to oxidative stressGO:00069791860.046
rna metabolic processGO:00160704060.046
rna biosynthetic processGO:00327743800.046
ion homeostasisGO:00508012120.045
rhythmic processGO:00485111560.045
negative regulation of cell deathGO:00605482290.044
female pregnancyGO:00075651220.044
single organism biosynthetic processGO:00447113420.044
neuron differentiationGO:00301823680.043
positive regulation of programmed cell deathGO:00430681570.043
neuron projection developmentGO:00311752730.043
positive regulation of biosynthetic processGO:00098913190.042
regulation of hydrolase activityGO:00513361430.042
chemical homeostasisGO:00488782920.041
locomotionGO:00400112370.041
protein localizationGO:00081041910.041
negative regulation of cellular metabolic processGO:00313242810.040
regulation of transcription dna templatedGO:00063553740.040
response to acid chemicalGO:00011012220.040
gland developmentGO:00487321550.040
regulation of catalytic activityGO:00507903040.040
protein complex subunit organizationGO:00718223020.039
transmembrane transportGO:00550854120.039
regulation of cell developmentGO:00602842630.039
protein complex assemblyGO:00064612630.039
response to inorganic substanceGO:00100353770.038
regulation of secretion by cellGO:19035302080.038
anatomical structure morphogenesisGO:00096532980.038
Mouse Rat
metal ion transportGO:00300012890.038
negative regulation of transportGO:00510511360.037
multicellular organismal reproductive processGO:00486092330.037
negative regulation of nucleobase containing compound metabolic processGO:00459341530.036
steroid metabolic processGO:0008202730.036
amine metabolic processGO:0009308380.036
nucleoside phosphate metabolic processGO:00067532830.035
response to peptideGO:19016522920.035
response to transition metal nanoparticleGO:19902671220.035
regulation of intracellular signal transductionGO:19025312180.035
response to estrogenGO:00436272320.034
response to hydrogen peroxideGO:0042542890.034
cellular amine metabolic processGO:0044106380.034
single organism reproductive processGO:00447022970.034
macromolecular complex assemblyGO:00650032730.034
learning or memoryGO:0007611900.034
single organism catabolic processGO:00447122830.034
response to purine containing compoundGO:00140741260.033
purine containing compound catabolic processGO:00725231380.033
regulation of system processGO:00440572080.032
oxoacid metabolic processGO:00434362900.032
response to ethanolGO:00454711620.032
macromolecule localizationGO:00330362520.032
response to growth factorGO:00708481890.032
monovalent inorganic cation transportGO:00156721720.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
organophosphate metabolic processGO:00196373700.031
response to vitaminGO:00332731310.031
positive regulation of catalytic activityGO:00430851840.031
central nervous system developmentGO:00074173110.030
positive regulation of response to stimulusGO:00485842850.030
regulation of neurogenesisGO:00507672470.030
steroid biosynthetic processGO:0006694480.030
positive regulation of transcription dna templatedGO:00458931970.030
positive regulation of cellular biosynthetic processGO:00313282950.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
single organism organelle organizationGO:19025891800.029
cellular response to lipidGO:00713962010.029
cofactor metabolic processGO:0051186950.029
regulation of apoptotic processGO:00429813350.029
cellular response to growth factor stimulusGO:00713631620.029
response to other organismGO:00517072200.029
ion transmembrane transportGO:00342203650.029
nitrogen compound transportGO:00717052290.029
cation transmembrane transportGO:00986552630.029
positive regulation of multicellular organismal processGO:00512403870.028
blood circulationGO:00080151830.028
developmental process involved in reproductionGO:00030061590.028
cellular response to organic cyclic compoundGO:00714072020.028
ribose phosphate metabolic processGO:00196932350.028
response to reactive oxygen speciesGO:00003021200.028
positive regulation of rna metabolic processGO:00512542030.028
negative regulation of metabolic processGO:00098923310.028
cell migrationGO:00164771970.027
cellular component assemblyGO:00226073600.027
regulation of epithelial cell proliferationGO:0050678490.027
nucleoside triphosphate catabolic processGO:00091431230.027
response to molecule of bacterial originGO:00022371940.027
response to campGO:0051591910.027
regulation of cell cycleGO:0051726730.027
cellular metal ion homeostasisGO:00068751720.027
cell projection organizationGO:00300303020.027
tissue developmentGO:00098882520.027
Mouse
organic acid metabolic processGO:00060822920.027
regulation of membrane potentialGO:00423911100.027
growthGO:00400071650.027
ras protein signal transductionGO:0007265290.026
positive regulation of cellular component organizationGO:00511302000.026
peptidyl amino acid modificationGO:00181931260.026
cellular component biogenesisGO:00440853680.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
response to lipopolysaccharideGO:00324961910.026
positive regulation of interleukin 1 beta secretionGO:005071830.026
regulation of cellular localizationGO:00603412630.025
g protein coupled receptor signaling pathwayGO:00071862420.025
response to biotic stimulusGO:00096072260.025
regulation of organelle organizationGO:0033043800.025
response to corticosteroidGO:00319602350.025
cellular protein localizationGO:00346131220.025
negative regulation of cell communicationGO:00106481580.025
cellular response to external stimulusGO:00714961180.024
organic acid transportGO:00158491160.024
regulation of signal transductionGO:00099663180.024
regulation of blood circulationGO:19035221100.024
response to activityGO:0014823730.024
organic substance catabolic processGO:19015753160.024
neuron developmentGO:00486662860.023
negative regulation of transcription dna templatedGO:00458921160.023
cation homeostasisGO:00550801950.023
cellular ketone metabolic processGO:0042180510.023
positive regulation of phosphorus metabolic processGO:00105622620.023
appendage morphogenesisGO:003510740.023
renal system developmentGO:0072001670.023
Mouse
cytosolic calcium ion homeostasisGO:00514801400.023
protein transportGO:00150311320.023
regulation of rna biosynthetic processGO:20011413810.023
regulation of cellular amine metabolic processGO:003323880.023
response to heatGO:0009408600.023
brain renin angiotensin systemGO:000203530.023
multicellular organismal homeostasisGO:0048871490.022
regulation of phosphate metabolic processGO:00192203490.022
regulation of metal ion transportGO:00109591180.022
carbohydrate derivative metabolic processGO:19011353460.022
epithelial cell proliferationGO:0050673540.022
circulatory system processGO:00030131830.022
macromolecular complex subunit organizationGO:00439333390.022
negative regulation of molecular functionGO:00440921330.022
metal ion homeostasisGO:00550651860.022
regulation of endocytosisGO:0030100420.022
negative regulation of cellular biosynthetic processGO:00313271610.022
regulation of locomotionGO:00400121480.021
acyl coa metabolic processGO:0006637280.021
cellular response to organonitrogen compoundGO:00714171970.021
sensory perceptionGO:00076001010.021
regulation of purine nucleotide metabolic processGO:19005421150.021
organonitrogen compound catabolic processGO:19015651790.021
organelle organizationGO:00069962660.021
ossificationGO:0001503700.021
coenzyme metabolic processGO:0006732860.021
actin filament based processGO:0030029860.021
regulation of growthGO:00400081050.021
action potentialGO:0001508540.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
signal transduction by phosphorylationGO:00230141440.021
cell motilityGO:00488702020.021
negative regulation of secretion by cellGO:1903531720.021
negative regulation of apoptotic processGO:00430661810.020
small gtpase mediated signal transductionGO:0007264360.020
positive regulation of hydrolase activityGO:0051345860.020
defense responseGO:00069521940.020
regulation of immune system processGO:00026821230.020
negative regulation of rna biosynthetic processGO:19026791180.020
secretion by cellGO:00329402480.020
positive regulation of rna biosynthetic processGO:19026801970.020
fatty acid biosynthetic processGO:0006633330.020
ovulation cycle processGO:0022602500.020
regulation of establishment of protein localizationGO:0070201690.020
positive regulation of phosphate metabolic processGO:00459372620.020
positive regulation of neurogenesisGO:00507691650.019
response to insulinGO:00328681330.019
negative regulation of glutamate secretionGO:001405090.019
cellular homeostasisGO:00197252520.019
positive regulation of signal transductionGO:00099671750.019
cellular catabolic processGO:00442482950.019
cellular response to peptide hormone stimulusGO:00713751200.019
positive regulation of phosphorylationGO:00423271770.019
synaptic transmissionGO:00072682350.019
organic hydroxy compound biosynthetic processGO:1901617510.019
inner medullary collecting duct developmentGO:007206110.019
regulation of nucleotide catabolic processGO:0030811650.019
multicellular organism reproductionGO:00325042330.019
receptor mediated endocytosisGO:0006898420.019
axis specificationGO:000979840.018
Rat
positive regulation of smooth muscle cell proliferationGO:0048661510.018
nucleobase containing compound catabolic processGO:00346551520.018
negative regulation of signalingGO:00230571570.018
regulation of phosphorylationGO:00423252480.018
nucleobase containing small molecule metabolic processGO:00550863160.018
gonad developmentGO:00084061040.018
positive regulation of intracellular signal transductionGO:19025331380.018
cellular cation homeostasisGO:00300031800.018
sexual reproductionGO:00199531480.018
regulation of cellular ketone metabolic processGO:0010565270.018
cell morphogenesisGO:00009021420.018
purine containing compound metabolic processGO:00725212530.018
response to ionizing radiationGO:0010212590.018
taxisGO:0042330670.018
positive regulation of molecular functionGO:00440932300.017
glycosyl compound catabolic processGO:19016581260.017
nucleotide metabolic processGO:00091172790.017
regulation of lipid metabolic processGO:0019216680.017
response to external biotic stimulusGO:00432072210.017
localization of cellGO:00516742020.017
regulation of anatomical structure sizeGO:00900661350.017
cell cycleGO:00070491010.017
angiotensin mediated drinking behaviorGO:000305120.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of cellular amino acid metabolic processGO:000652120.017
ribonucleotide metabolic processGO:00092592310.017
small molecule biosynthetic processGO:00442831240.017
cellular macromolecule localizationGO:00707271220.017
negative regulation of macromolecule metabolic processGO:00106052600.017
response to cytokineGO:00340972150.017
locomotor rhythmGO:004547510.017
transcription dna templatedGO:00063513770.017
transmission of nerve impulseGO:0019226420.017
response to glucoseGO:00097491360.016
embryonic appendage morphogenesisGO:003511340.016
sulfur compound metabolic processGO:0006790700.016
calcium ion transportGO:00068161310.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
positive regulation of nervous system developmentGO:00519621780.016
activation of protein kinase activityGO:0032147470.016
cell morphogenesis involved in differentiationGO:00009041190.016
immune system processGO:00023762040.016
cellular response to insulin stimulusGO:0032869810.016
cellular response to iron iii ionGO:007128330.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
sodium ion transportGO:0006814820.016
cellular response to peptideGO:19016531330.016
kidney developmentGO:0001822670.016
Mouse
ribonucleoside triphosphate metabolic processGO:00091991410.016
protein heterooligomerizationGO:0051291890.016
organic cyclic compound catabolic processGO:19013611750.016
regulation of nervous system developmentGO:00519602640.015
positive regulation of cell developmentGO:00107201760.015
cellular ion homeostasisGO:00068731840.015
positive regulation of gene expressionGO:00106282440.015
cellular calcium ion homeostasisGO:00068741600.015
organic anion transportGO:00157111320.015
phenol containing compound metabolic processGO:0018958300.015
peptidyl tyrosine phosphorylationGO:0018108720.015
response to indole 3 methanolGO:007168020.015
divalent inorganic cation transportGO:00725111340.015
regulation of synaptic transmissionGO:00508041410.015
negative regulation of rna metabolic processGO:00512531230.015
regulation of rna metabolic processGO:00512523910.015
cellular response to fluid shear stressGO:007149840.015
divalent inorganic cation homeostasisGO:00725071650.015
catabolic processGO:00090563510.015
smooth muscle cell proliferationGO:0048659770.015
gtp catabolic processGO:0006184710.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
regulation of lipid biosynthetic processGO:0046890380.015
purine nucleotide metabolic processGO:00061632290.015
regulation of phosphorus metabolic processGO:00511743490.015
response to monosaccharideGO:00342841590.015
circadian rhythmGO:0007623880.015
transcription from rna polymerase ii promoterGO:00063662520.015
positive regulation of developmental processGO:00510942830.015
heterocycle catabolic processGO:00467001670.014
carboxylic acid transportGO:00469421150.014
negative regulation of biosynthetic processGO:00098901680.014
embryo developmentGO:0009790490.014
Mouse
regulation of hormone levelsGO:00108171870.014
cellular response to extracellular stimulusGO:0031668730.014
regenerationGO:00310991630.014
response to retinoic acidGO:0032526630.014
hormone secretionGO:00468791150.014
protein oligomerizationGO:00512591910.014
positive regulation of cellular amine metabolic processGO:003324030.014
developmental growthGO:00485891000.014
carbohydrate derivative catabolic processGO:19011361470.014
ribonucleoside metabolic processGO:00091191740.014
axon developmentGO:0061564960.014
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.014
purine nucleoside catabolic processGO:00061521240.014
positive regulation of cellular component movementGO:00512721020.014
morphogenesis of a polarized epitheliumGO:000173810.014
choline transportGO:001587140.014
response to low density lipoprotein particleGO:005509840.014
cellular response to cytokine stimulusGO:00713451270.013
guanosine containing compound metabolic processGO:1901068740.013
regulation of cytoskeleton organizationGO:0051493490.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
Mouse
positive regulation of kinase activityGO:0033674770.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
development of primary sexual characteristicsGO:00451371070.013
purine ribonucleoside metabolic processGO:00461281680.013
limb morphogenesisGO:003510840.013
regulation of amine transportGO:0051952540.013
negative regulation of gene expressionGO:00106291990.013
multicellular organismal signalingGO:0035637440.013
positive regulation of epithelial cell proliferationGO:0050679320.013
circulatory system developmentGO:00723591340.013
sex differentiationGO:00075481130.013
biological adhesionGO:00226101100.013
intracellular protein transportGO:0006886790.013
regulation of kinase activityGO:00435491170.013
vascular process in circulatory systemGO:0003018960.013
regulation of ion transportGO:00432692450.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
positive regulation of calcium ion transportGO:0051928360.013
regulation of cell projection organizationGO:00313441750.013
ovulation cycleGO:0042698670.013
organonitrogen compound biosynthetic processGO:19015661670.013
nucleoside phosphate catabolic processGO:19012921400.013
establishment of tissue polarityGO:000716420.013
protein homooligomerizationGO:0051260910.013
regulation of cell migrationGO:00303341280.013
response to bacteriumGO:00096172000.013
signal releaseGO:00230611450.013
hormone metabolic processGO:0042445690.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
regulation of vesicle mediated transportGO:0060627810.013
positive regulation of blood circulationGO:1903524650.013
thioester metabolic processGO:0035383280.013
cytoskeleton organizationGO:00070101110.012
cellular response to alcoholGO:0097306870.012
organophosphate catabolic processGO:00464341480.012
regulation of response to external stimulusGO:00321011060.012
monocarboxylic acid biosynthetic processGO:0072330480.012
urogenital system developmentGO:0001655780.012
Mouse
regulation of cell activationGO:0050865500.012
micturitionGO:006007340.012
regulation of gtpase activityGO:0043087570.012
embryonic limb morphogenesisGO:003032640.012
regulation of hormone secretionGO:00468831060.012
response to mechanical stimulusGO:00096121340.012
cellular response to oxygen levelsGO:0071453600.012
regulation of mapk cascadeGO:00434081160.012
behaviorGO:00076102050.012
regulation of proteolysisGO:0030162660.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
dendrite morphogenesisGO:0048813430.012
positive regulation of protein metabolic processGO:00512471780.012
regulation of transferase activityGO:00513381230.012
oxidation reduction processGO:00551143040.012
regulation of protein kinase activityGO:00458591050.012
regulation of protein phosphorylationGO:00019321830.012
regulation of organic acid transportGO:0032890350.012
salivary gland developmentGO:000743130.012
inflammatory responseGO:00069541500.012
heart developmentGO:0007507720.012
regulation of peptidase activityGO:0052547550.012
regulation of homeostatic processGO:00328441010.012
cell activationGO:0001775970.012
vasoconstrictionGO:0042310540.012
muscle cell proliferationGO:0033002840.012
male sex differentiationGO:0046661640.012
cellular response to abiotic stimulusGO:0071214850.011
regulation of cellular protein metabolic processGO:00322682670.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
intracellular transportGO:00469071850.011
response to toxic substanceGO:00096361330.011
vesicle mediated transportGO:00161921810.011
cellular response to drugGO:0035690300.011
regulation of neuron projection developmentGO:00109751610.011
prostate gland epithelium morphogenesisGO:006074020.011
positive regulation of cell motilityGO:2000147970.011
nucleotide catabolic processGO:00091661390.011
gtp metabolic processGO:0046039720.011
positive regulation of nucleotide metabolic processGO:0045981910.011
rho protein signal transductionGO:0007266110.011
regulation of response to stressGO:00801341260.011
purine nucleotide catabolic processGO:00061951360.011
mapk cascadeGO:00001651400.011
cytolysisGO:001983540.011
regulation of cellular catabolic processGO:00313291010.011
embryonic pattern specificationGO:000988010.011
vasculature developmentGO:0001944700.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
guanosine containing compound catabolic processGO:1901069710.011
leukocyte migrationGO:0050900380.011
regulation of calcium ion transportGO:0051924770.011
multicellular organism growthGO:003526410.011
protein maturationGO:0051604680.011
positive regulation of protein transportGO:0051222410.011
cellular response to nutrient levelsGO:0031669600.011
forebrain developmentGO:0030900980.011
response to high light intensityGO:000964410.011
regulation of peptide transportGO:0090087870.011
heart morphogenesisGO:000300730.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
regulation of ras protein signal transductionGO:0046578450.011
regulation of interleukin 1 beta secretionGO:005070630.011
positive regulation of cell differentiationGO:00455972170.011
cellular response to low density lipoprotein particle stimulusGO:007140430.011
alcohol metabolic processGO:0006066770.010
regulation of peptide hormone secretionGO:0090276800.010
leukocyte activationGO:0045321760.010
wound healingGO:00420601220.010
regulation of cell motilityGO:20001451310.010
positive regulation of protein phosphorylationGO:00019341350.010
cellular response to hexose stimulusGO:0071331650.010
protein phosphorylationGO:00064683450.010
positive regulation of secretion by cellGO:19035321280.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
purine nucleoside metabolic processGO:00422781690.010
carboxylic acid biosynthetic processGO:0046394830.010
response to glucocorticoidGO:00513842230.010
brain developmentGO:00074202470.010
carboxylic acid metabolic processGO:00197522890.010
regulation of defense responseGO:0031347680.010
lipid storageGO:001991510.010
nucleoside triphosphate metabolic processGO:00091411440.010

Irx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.033
eye diseaseDOID:561400.033
disease of anatomical entityDOID:700.033
retinal degenerationDOID:846600.033
retinal diseaseDOID:567900.033
eye and adnexa diseaseDOID:149200.033
retinitis pigmentosaDOID:1058400.033
nervous system diseaseDOID:86300.033
musculoskeletal system diseaseDOID:1700.024
connective tissue diseaseDOID:6500.023
bone diseaseDOID:008000100.016
cardiovascular system diseaseDOID:128700.011