Rattus norvegicus

0 known processes

Polr2a

polymerase (RNA) II (DNA directed) polypeptide A

(Aliases: Rpo2-1)

Polr2a biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nitrogen compound metabolic processGO:00511721610.132
cell projection organizationGO:00300303020.106
negative regulation of cellular metabolic processGO:00313242810.095
intracellular transportGO:00469071850.086
regulation of signal transductionGO:00099663180.075
positive regulation of response to stimulusGO:00485842850.072
positive regulation of nucleobase containing compound metabolic processGO:00459353190.071
positive regulation of cell communicationGO:00106472710.071
response to extracellular stimulusGO:00099913800.070
positive regulation of gene expressionGO:00106282440.070
positive regulation of nitrogen compound metabolic processGO:00511733340.069
response to nutrient levelsGO:00316673700.069
positive regulation of biosynthetic processGO:00098913190.066
positive regulation of transcription dna templatedGO:00458931970.065
organelle organizationGO:00069962660.065
positive regulation of signalingGO:00230562700.063
multi organism reproductive processGO:00447032620.062
intracellular signal transductionGO:00355563140.062
regulation of cellular localizationGO:00603412630.061
response to peptideGO:19016522920.061
single organism organelle organizationGO:19025891800.060
regulation of molecular functionGO:00650093980.057
locomotionGO:00400112370.055
negative regulation of transcription dna templatedGO:00458921160.053
response to campGO:0051591910.053
positive regulation of transportGO:00510502450.053
cellular response to oxygen containing compoundGO:19017013860.052
reproductive processGO:00224143720.052
negative regulation of metabolic processGO:00098923310.051
carboxylic acid metabolic processGO:00197522890.050
transcription dna templatedGO:00063513770.048
single organism intracellular transportGO:19025821660.047
neuron projection developmentGO:00311752730.046
apoptotic processGO:00069153810.046
regulation of catalytic activityGO:00507903040.045
positive regulation of rna biosynthetic processGO:19026801970.045
response to nutrientGO:00075842480.045
regulation of secretionGO:00510462240.044
homeostatic processGO:00425923310.044
neuron differentiationGO:00301823680.044
central nervous system developmentGO:00074173110.043
neurological system processGO:00508772190.041
response to estrogenGO:00436272320.041
macromolecular complex subunit organizationGO:00439333390.039
response to external biotic stimulusGO:00432072210.039
positive regulation of rna metabolic processGO:00512542030.039
negative regulation of nucleobase containing compound metabolic processGO:00459341530.038
growthGO:00400071650.038
negative regulation of macromolecule metabolic processGO:00106052600.038
response to inorganic substanceGO:00100353770.038
cellular component assemblyGO:00226073600.038
reproductionGO:00000032450.038
cellular component biogenesisGO:00440853680.038
cellular amino acid metabolic processGO:00065201070.037
head developmentGO:00603222470.037
regulation of transcription dna templatedGO:00063553740.037
negative regulation of signalingGO:00230571570.037
negative regulation of cell deathGO:00605482290.037
cellular response to stressGO:00335542690.036
negative regulation of macromolecule biosynthetic processGO:00105581480.036
negative regulation of rna metabolic processGO:00512531230.036
regenerationGO:00310991630.035
negative regulation of programmed cell deathGO:00430691830.035
agingGO:00075682410.035
response to biotic stimulusGO:00096072260.035
oxoacid metabolic processGO:00434362900.034
establishment of protein localizationGO:00451841410.034
response to metal ionGO:00100382530.034
multicellular organismal reproductive processGO:00486092330.034
amine metabolic processGO:0009308380.034
rna metabolic processGO:00160704060.034
cellular component morphogenesisGO:00329891550.034
response to lipopolysaccharideGO:00324961910.034
single organism behaviorGO:00447081300.033
regulation of intracellular signal transductionGO:19025312180.033
regulation of cell developmentGO:00602842630.032
transcription from rna polymerase ii promoterGO:00063662520.032
regulation of cell proliferationGO:00421273590.032
nucleic acid templated transcriptionGO:00976593790.031
regulation of rna metabolic processGO:00512523910.031
behaviorGO:00076102050.031
cell motilityGO:00488702020.031
response to ethanolGO:00454711620.031
response to other organismGO:00517072200.030
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
chemical homeostasisGO:00488782920.030
defense responseGO:00069521940.030
cellular component movementGO:00069282480.030
regulation of protein metabolic processGO:00512462890.030
protein phosphorylationGO:00064683450.030
regulation of rna biosynthetic processGO:20011413810.030
regulation of cellular component organizationGO:00511283680.030
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
negative regulation of nucleic acid templated transcriptionGO:19035071170.029
negative regulation of gene expressionGO:00106291990.029
response to glucocorticoidGO:00513842230.029
cellular chemical homeostasisGO:00550822470.029
immune system processGO:00023762040.029
macromolecule localizationGO:00330362520.029
regulation of programmed cell deathGO:00430673410.029
cellular response to endogenous stimulusGO:00714953770.029
metal ion homeostasisGO:00550651860.028
hepaticobiliary system developmentGO:0061008900.028
positive regulation of phosphate metabolic processGO:00459372620.028
regulation of multicellular organismal developmentGO:20000263760.028
negative regulation of protein metabolic processGO:00512481140.028
tissue developmentGO:00098882520.028
positive regulation of molecular functionGO:00440932300.028
cell part morphogenesisGO:00329901230.028
response to peptide hormoneGO:00434342780.027
carbohydrate derivative metabolic processGO:19011353460.027
single organism reproductive processGO:00447022970.027
organic hydroxy compound metabolic processGO:19016151150.026
positive regulation of signal transductionGO:00099671750.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
rna biosynthetic processGO:00327743800.026
response to carbohydrateGO:00097431830.026
sexual reproductionGO:00199531480.026
response to oxidative stressGO:00069791860.026
response to monosaccharideGO:00342841590.026
response to decreased oxygen levelsGO:00362932370.025
negative regulation of cell communicationGO:00106481580.025
regulation of phosphate metabolic processGO:00192203490.025
regulation of cellular amino acid metabolic processGO:000652120.025
cellular response to organonitrogen compoundGO:00714171970.025
response to purine containing compoundGO:00140741260.025
ion homeostasisGO:00508012120.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
anatomical structure morphogenesisGO:00096532980.025
negative regulation of response to stimulusGO:00485851550.025
cellular macromolecule localizationGO:00707271220.024
response to oxygen levelsGO:00704822650.024
cell cycleGO:00070491010.024
negative regulation of multicellular organismal processGO:00512412030.024
regulation of cellular protein metabolic processGO:00322682670.024
regulation of cellular ketone metabolic processGO:0010565270.024
regulation of cell differentiationGO:00455953200.024
cytoplasmic transportGO:00164821150.024
regulation of cell migrationGO:00303341280.024
peptidyl amino acid modificationGO:00181931260.023
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.023
negative regulation of biosynthetic processGO:00098901680.023
positive regulation of cell differentiationGO:00455972170.023
neuron developmentGO:00486662860.023
negative regulation of rna biosynthetic processGO:19026791180.023
negative regulation of cellular biosynthetic processGO:00313271610.022
regulation of neuron differentiationGO:00456642080.022
response to growth factorGO:00708481890.022
cell projection morphogenesisGO:00488581230.022
protein complex assemblyGO:00064612630.022
positive regulation of cellular protein metabolic processGO:00322701670.022
cellular response to growth factor stimulusGO:00713631620.022
divalent inorganic cation homeostasisGO:00725071650.022
cell morphogenesisGO:00009021420.021
single organism biosynthetic processGO:00447113420.021
response to woundingGO:00096112540.021
negative regulation of cell developmentGO:0010721820.021
brain developmentGO:00074202470.021
response to corticosteroidGO:00319602350.021
mechanoreceptor differentiationGO:004249020.021
inner ear receptor cell differentiationGO:006011320.021
positive regulation of cellular biosynthetic processGO:00313282950.021
cation homeostasisGO:00550801950.021
response to glucoseGO:00097491360.021
organic acid metabolic processGO:00060822920.021
negative regulation of cellular protein metabolic processGO:00322691060.021
hair cell differentiationGO:003531520.020
response to hypoxiaGO:00016662310.020
cell morphogenesis involved in differentiationGO:00009041190.020
positive regulation of neurogenesisGO:00507691650.020
cellular response to organic cyclic compoundGO:00714072020.020
multicellular organism reproductionGO:00325042330.020
multicellular organism growthGO:003526410.020
regulation of nervous system developmentGO:00519602640.020
response to estradiolGO:00323551640.020
regulation of cellular amine metabolic processGO:003323880.020
axon guidanceGO:0007411240.020
positive regulation of cell developmentGO:00107201760.020
single organism cellular localizationGO:19025801020.019
positive regulation of cellular component organizationGO:00511302000.019
cellular homeostasisGO:00197252520.019
positive regulation of developmental processGO:00510942830.019
protein complex biogenesisGO:00702712630.019
secretionGO:00469033070.019
axon developmentGO:0061564960.019
regulation of cellular component movementGO:00512701500.019
response to transition metal nanoparticleGO:19902671220.019
macromolecular complex assemblyGO:00650032730.019
response to hexoseGO:00097461440.019
taxisGO:0042330670.019
positive regulation of multicellular organismal processGO:00512403870.019
protein complex subunit organizationGO:00718223020.018
protein transportGO:00150311320.018
cell adhesionGO:00071551100.018
cellular amine metabolic processGO:0044106380.018
cellular ketone metabolic processGO:0042180510.018
cellular response to insulin stimulusGO:0032869810.018
response to molecule of bacterial originGO:00022371940.018
intracellular protein transportGO:0006886790.017
positive regulation of cell deathGO:00109421840.017
regulation of neurogenesisGO:00507672470.017
negative regulation of apoptotic processGO:00430661810.017
regulation of phosphorus metabolic processGO:00511743490.017
liver developmentGO:0001889900.017
response to organophosphorusGO:00466831020.017
regulation of locomotionGO:00400121480.017
localization of cellGO:00516742020.017
cell cell signalingGO:00072673350.017
regulation of protein localizationGO:0032880810.017
proteolysisGO:00065081750.017
regulation of establishment of protein localizationGO:0070201690.017
cellular protein localizationGO:00346131220.017
protein importGO:0017038370.017
regulation of secretion by cellGO:19035302080.017
negative regulation of cell proliferationGO:00082851190.017
regulation of cell motilityGO:20001451310.017
gamete generationGO:00072761240.017
response to reactive oxygen speciesGO:00003021200.017
response to acid chemicalGO:00011012220.016
cellular response to hormone stimulusGO:00328702470.016
cellular cation homeostasisGO:00300031800.016
positive regulation of nervous system developmentGO:00519621780.016
establishment of protein localization to organelleGO:0072594440.016
covalent chromatin modificationGO:0016569300.016
lipid metabolic processGO:00066292830.016
response to mechanical stimulusGO:00096121340.016
regulation of apoptotic processGO:00429813350.016
vesicle mediated transportGO:00161921810.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
positive regulation of protein phosphorylationGO:00019341350.016
cellular response to peptideGO:19016531330.016
response to temperature stimulusGO:0009266940.016
regulation of homeostatic processGO:00328441010.016
dna metabolic processGO:0006259960.016
female pregnancyGO:00075651220.016
organ morphogenesisGO:0009887750.016
cell morphogenesis involved in neuron differentiationGO:00486671060.016
protein localizationGO:00081041910.016
positive regulation of ion transportGO:0043270940.016
cellular metal ion homeostasisGO:00068751720.015
cellular response to lipidGO:00713962010.015
carbohydrate derivative biosynthetic processGO:19011371240.015
negative regulation of signal transductionGO:0009968830.015
regulation of phosphorylationGO:00423252480.015
regulation of protein phosphorylationGO:00019321830.015
regulation of activation of janus kinase activityGO:001053310.015
negative regulation of cell differentiationGO:0045596990.015
multi multicellular organism processGO:00447061380.015
eye morphogenesisGO:004859240.015
single organism nuclear importGO:1902593350.015
regulation of membrane potentialGO:00423911100.015
regulation of system processGO:00440572080.015
chromatin modificationGO:0016568330.015
ras protein signal transductionGO:0007265290.015
positive regulation of programmed cell deathGO:00430681570.015
response to bacteriumGO:00096172000.015
spermatogenesisGO:0007283990.015
cellular response to nitrogen compoundGO:19016992100.015
protein localization to organelleGO:0033365570.015
gland developmentGO:00487321550.015
calcium ion transportGO:00068161310.015
positive regulation of cell proliferationGO:00082842490.015
heart morphogenesisGO:000300730.015
response to ketoneGO:19016541820.015
positive regulation of neuron differentiationGO:00456661260.015
divalent inorganic cation transportGO:00725111340.014
regulation of peptide secretionGO:0002791820.014
regulation of intracellular transportGO:0032386650.014
positive regulation of protein metabolic processGO:00512471780.014
positive regulation of cellular amine metabolic processGO:003324030.014
ribonucleotide biosynthetic processGO:0009260850.014
programmed cell deathGO:00125013920.014
negative regulation of protein import into nucleus translocationGO:003315910.014
negative regulation of transportGO:00510511360.014
axis specificationGO:000979840.014
cellular calcium ion homeostasisGO:00068741600.014
muscle tissue developmentGO:0060537580.014
calcium ion homeostasisGO:00550741620.014
positive regulation of phosphorylationGO:00423271770.014
urogenital system developmentGO:0001655780.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
jak stat cascadeGO:0007259260.014
negative regulation of nervous system developmentGO:0051961790.014
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.014
regulation of protein kinase activityGO:00458591050.013
positive regulation of phosphorus metabolic processGO:00105622620.013
reproductive structure developmentGO:00486081280.013
axonogenesisGO:0007409710.013
positive regulation of catalytic activityGO:00430851840.013
organophosphate metabolic processGO:00196373700.013
organonitrogen compound biosynthetic processGO:19015661670.013
regulation of neuron projection developmentGO:00109751610.013
response to radiationGO:00093141370.013
male gamete generationGO:0048232990.013
muscle structure developmentGO:0061061870.013
response to cytokineGO:00340972150.013
protein import into nucleusGO:0006606350.013
retinal ganglion cell axon guidanceGO:003129010.013
spindle organizationGO:000705120.013
protein maturationGO:0051604680.013
nucleotide biosynthetic processGO:0009165980.013
regulation of protein transportGO:0051223680.013
protein targeting to nucleusGO:0044744350.013
secretion by cellGO:00329402480.013
metal ion transportGO:00300012890.013
developmental process involved in reproductionGO:00030061590.012
circulatory system processGO:00030131830.012
digestive system developmentGO:0055123410.012
negative regulation of developmental processGO:00510931250.012
chromatin organizationGO:0006325340.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
regulation of peptide hormone secretionGO:0090276800.012
cellular response to abiotic stimulusGO:0071214850.012
reproductive system developmentGO:00614581280.012
nucleocytoplasmic transportGO:0006913480.012
glial cell differentiationGO:0010001650.012
immune responseGO:00069551040.012
neuron projection morphogenesisGO:00488121220.012
regulation of hydrolase activityGO:00513361430.012
nucleoside phosphate biosynthetic processGO:19012931020.012
regulation of kinase activityGO:00435491170.012
establishment of tissue polarityGO:000716420.012
carbohydrate homeostasisGO:0033500750.012
blood circulationGO:00080151830.012
reactive oxygen species metabolic processGO:0072593370.011
positive regulation of protein transportGO:0051222410.011
negative regulation of molecular functionGO:00440921330.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
regulation of nucleocytoplasmic transportGO:0046822280.011
regulation of transferase activityGO:00513381230.011
neural crest cell migrationGO:000175510.011
negative regulation of neurogenesisGO:0050768780.011
regulation of dna metabolic processGO:0051052600.011
cellular lipid metabolic processGO:00442552080.011
maintenance of locationGO:0051235170.011
regulation of nucleotide metabolic processGO:00061401170.011
organic substance catabolic processGO:19015753160.011
organophosphate biosynthetic processGO:00904071430.011
muscle cell proliferationGO:0033002840.011
gliogenesisGO:0042063930.011
positive regulation of apoptotic processGO:00430651540.011
regulation of hormone levelsGO:00108171870.011
single organism carbohydrate metabolic processGO:00447231180.011
purine nucleotide metabolic processGO:00061632290.011
positive regulation of neuron projection developmentGO:0010976990.011
positive regulation of hydrolase activityGO:0051345860.011
small gtpase mediated signal transductionGO:0007264360.011
cofactor metabolic processGO:0051186950.011
peptidyl tyrosine phosphorylationGO:0018108720.011
chemotaxisGO:0006935660.011
regulation of intracellular protein transportGO:0033157340.011
auditory receptor cell differentiationGO:004249120.011
regulation of body fluid levelsGO:0050878900.011
regulation of cell cycleGO:0051726730.011
regulation of protein modification processGO:00313991940.011
neural crest cell differentiationGO:001403320.010
cellular ion homeostasisGO:00068731840.010
positive regulation of locomotionGO:00400171020.010
chromatin remodelingGO:000633830.010
digestive tract developmentGO:0048565390.010
intracellular receptor signaling pathwayGO:0030522350.010
regulation of mesenchymal cell proliferationGO:001046440.010
nitrogen compound transportGO:00717052290.010
glucose homeostasisGO:0042593750.010
positive regulation of protein modification processGO:00314011420.010
dephosphorylationGO:0016311980.010
regulation of anatomical structure sizeGO:00900661350.010
motor neuron axon guidanceGO:000804510.010
carbohydrate metabolic processGO:00059751300.010
tube developmentGO:0035295890.010

Polr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.013
sensory system diseaseDOID:005015500.010