Rattus norvegicus

19 known processes

Afp

alpha-fetoprotein

Afp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of programmed cell deathGO:00430673410.288
cellular response to organic cyclic compoundGO:00714072020.252
response to peptideGO:19016522920.237
regulation of molecular functionGO:00650093980.233
apoptotic processGO:00069153810.229
response to extracellular stimulusGO:00099913800.227
Rat
response to metal ionGO:00100382530.223
Rat
cellular amino acid metabolic processGO:00065201070.203
response to campGO:0051591910.185
cellular response to nitrogen compoundGO:19016992100.183
regulation of apoptotic processGO:00429813350.183
response to peptide hormoneGO:00434342780.174
programmed cell deathGO:00125013920.169
secretionGO:00469033070.167
Rat
cellular ketone metabolic processGO:0042180510.161
response to woundingGO:00096112540.152
positive regulation of extracellular matrix constituent secretionGO:000333120.150
catabolic processGO:00090563510.147
response to mineralocorticoidGO:0051385490.141
oxoacid metabolic processGO:00434362900.139
response to hypoxiaGO:00016662310.130
response to nutrient levelsGO:00316673700.126
Rat
regulation of catalytic activityGO:00507903040.125
cellular response to endogenous stimulusGO:00714953770.124
cellular response to oxygen containing compoundGO:19017013860.123
cellular response to peptide hormone stimulusGO:00713751200.121
cellular response to lipidGO:00713962010.119
cellular response to external stimulusGO:00714961180.118
response to glucocorticoidGO:00513842230.118
protein localizationGO:00081041910.108
cellular response to insulin stimulusGO:0032869810.101
renin angiotensin regulation of aldosterone productionGO:000201830.098
negative regulation of programmed cell deathGO:00430691830.094
cellular response to hormone stimulusGO:00328702470.093
amine metabolic processGO:0009308380.092
regulation of cellular localizationGO:00603412630.089
response to corticosteroidGO:00319602350.087
response to acid chemicalGO:00011012220.087
female pregnancyGO:00075651220.087
Rat
reproductive processGO:00224143720.086
Rat
negative regulation of metabolic processGO:00098923310.084
response to purine containing compoundGO:00140741260.084
carboxylic acid metabolic processGO:00197522890.082
macromolecule localizationGO:00330362520.082
liver developmentGO:0001889900.080
alpha amino acid metabolic processGO:1901605710.077
response to transition metal nanoparticleGO:19902671220.075
Rat
response to nutrientGO:00075842480.071
Rat
cellular amino acid catabolic processGO:0009063210.071
regulation of cellular protein metabolic processGO:00322682670.069
macromolecular complex subunit organizationGO:00439333390.069
response to decreased oxygen levelsGO:00362932370.069
regulation of phosphate metabolic processGO:00192203490.068
response to carbohydrateGO:00097431830.068
organic acid metabolic processGO:00060822920.068
alpha amino acid catabolic processGO:1901606200.065
organ regenerationGO:00311001010.065
organic substance catabolic processGO:19015753160.064
aromatic compound catabolic processGO:00194391680.064
positive regulation of transportGO:00510502450.064
cellular catabolic processGO:00442482950.062
regulation of cellular ketone metabolic processGO:0010565270.062
nucleobase containing small molecule metabolic processGO:00550863160.062
cellular amine metabolic processGO:0044106380.062
response to estrogenGO:00436272320.061
Rat
negative regulation of apoptotic processGO:00430661810.061
positive regulation of biosynthetic processGO:00098913190.060
positive regulation of nitrogen compound metabolic processGO:00511733340.060
gland developmentGO:00487321550.060
cellular response to stressGO:00335542690.060
divalent inorganic cation transportGO:00725111340.060
regulation of hydrolase activityGO:00513361430.058
hepaticobiliary system developmentGO:0061008900.058
regulation of multicellular organismal developmentGO:20000263760.058
regulation of cellular amine metabolic processGO:003323880.058
purine nucleoside metabolic processGO:00422781690.056
transmission of nerve impulseGO:0019226420.056
positive regulation of cellular biosynthetic processGO:00313282950.054
metal ion transportGO:00300012890.054
response to external biotic stimulusGO:00432072210.054
positive regulation of molecular functionGO:00440932300.054
regulation of serine type endopeptidase activityGO:190000310.053
negative regulation of macromolecule metabolic processGO:00106052600.053
regulation of secretionGO:00510462240.053
proteolysisGO:00065081750.053
positive regulation of multicellular organismal processGO:00512403870.052
Rat
negative regulation of multicellular organismal processGO:00512412030.052
negative regulation of cell deathGO:00605482290.051
tonic smooth muscle contractionGO:001482040.051
positive regulation of extracellular matrix organizationGO:190305540.050
purine containing compound catabolic processGO:00725231380.049
organonitrogen compound catabolic processGO:19015651790.049
cell cell signalingGO:00072673350.049
extracellular matrix constituent secretionGO:007027840.049
negative regulation of cellular protein metabolic processGO:00322691060.049
cellular response to organonitrogen compoundGO:00714171970.049
response to lipopolysaccharideGO:00324961910.048
single organism catabolic processGO:00447122830.048
regulation of cellular amino acid metabolic processGO:000652120.048
cellular response to abiotic stimulusGO:0071214850.048
response to oxygen levelsGO:00704822650.048
carboxylic acid catabolic processGO:0046395490.047
purine ribonucleotide metabolic processGO:00091502270.047
response to organophosphorusGO:00466831020.047
response to corticosteroneGO:0051412400.046
developmental growthGO:00485891000.046
response to inorganic substanceGO:00100353770.046
Rat
regulation of proteasomal protein catabolic processGO:006113640.045
intracellular signal transductionGO:00355563140.045
carbohydrate derivative metabolic processGO:19011353460.045
positive regulation of hydrolase activityGO:0051345860.045
positive regulation of catalytic activityGO:00430851840.044
nucleobase containing compound catabolic processGO:00346551520.044
nucleoside monophosphate metabolic processGO:0009123930.044
macromolecular complex assemblyGO:00650032730.043
response to toxic substanceGO:00096361330.043
regulation of angiogenesisGO:0045765390.043
regulation of serine type peptidase activityGO:190257110.043
atp metabolic processGO:0046034720.043
regulation of protein metabolic processGO:00512462890.042
regenerationGO:00310991630.042
regulation of cellular component organizationGO:00511283680.041
cellular nitrogen compound catabolic processGO:00442701630.041
response to estradiolGO:00323551640.040
Rat
negative regulation of cellular metabolic processGO:00313242810.040
cellular response to peptideGO:19016531330.040
negative regulation of protein maturationGO:1903318470.039
neurological system processGO:00508772190.038
negative regulation of signalingGO:00230571570.038
aromatic amino acid family catabolic processGO:000907470.038
protein transportGO:00150311320.038
protein complex subunit organizationGO:00718223020.037
tissue developmentGO:00098882520.037
nucleoside metabolic processGO:00091161790.037
cellular response to steroid hormone stimulusGO:0071383930.037
homeostatic processGO:00425923310.037
organophosphate catabolic processGO:00464341480.037
multi multicellular organism processGO:00447061380.037
Rat
cellular component assemblyGO:00226073600.036
cell substrate adhesionGO:0031589290.036
purine containing compound metabolic processGO:00725212530.036
response to insulinGO:00328681330.036
peptide secretionGO:0002790860.036
regulation of growthGO:00400081050.036
cellular protein localizationGO:00346131220.036
cellular response to extracellular stimulusGO:0031668730.035
cellular response to corticosteroid stimulusGO:0071384690.035
generation of precursor metabolites and energyGO:0006091620.034
organic acid catabolic processGO:0016054490.034
purine nucleotide metabolic processGO:00061632290.034
transmembrane transportGO:00550854120.034
negative regulation of molecular functionGO:00440921330.034
amide transportGO:00428861050.033
purine ribonucleoside metabolic processGO:00461281680.033
response to alkaloidGO:00432791320.033
intracellular transportGO:00469071850.033
establishment of protein localizationGO:00451841410.033
purine ribonucleoside triphosphate metabolic processGO:00092051400.033
immune system processGO:00023762040.032
positive regulation of secretion by cellGO:19035321280.032
organophosphate metabolic processGO:00196373700.032
positive regulation of cellular amino acid metabolic processGO:004576410.032
positive regulation of protein metabolic processGO:00512471780.032
regulation of phosphorus metabolic processGO:00511743490.032
nucleoside triphosphate metabolic processGO:00091411440.032
heterocycle catabolic processGO:00467001670.032
sex differentiationGO:00075481130.031
gamete generationGO:00072761240.031
cell growthGO:00160491040.031
response to bacteriumGO:00096172000.031
regulation of body fluid levelsGO:0050878900.031
Rat
cognitionGO:0050890920.031
negative regulation of gene expressionGO:00106291990.031
positive regulation of cellular amine metabolic processGO:003324030.030
regulation of cell differentiationGO:00455953200.030
regulation of catecholamine secretionGO:0050433320.030
response to muscle activity involved in regulation of muscle adaptationGO:001487320.029
regulation of protein maturationGO:1903317500.029
positive regulation of blood coagulationGO:003019440.029
multi organism reproductive processGO:00447032620.029
Rat
cellular component biogenesisGO:00440853680.029
chemical homeostasisGO:00488782920.029
negative regulation of protein metabolic processGO:00512481140.029
cellular response to glucocorticoid stimulusGO:0071385680.029
purine nucleoside triphosphate metabolic processGO:00091441410.029
nucleoside phosphate metabolic processGO:00067532830.029
cellular homeostasisGO:00197252520.029
single organism carbohydrate metabolic processGO:00447231180.029
response to other organismGO:00517072200.029
reactive oxygen species metabolic processGO:0072593370.028
protein maturationGO:0051604680.028
ribonucleotide metabolic processGO:00092592310.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
organelle organizationGO:00069962660.028
ribonucleoside monophosphate metabolic processGO:0009161880.028
positive regulation of phosphorylationGO:00423271770.028
folic acid containing compound metabolic processGO:0006760100.028
response to molecule of bacterial originGO:00022371940.027
regulation of protein processingGO:0070613500.027
response to fungicideGO:0060992200.027
single organism biosynthetic processGO:00447113420.027
response to vitamin b6GO:003451610.027
regulation of system processGO:00440572080.027
regulation of blood circulationGO:19035221100.026
negative regulation of protein processingGO:0010955470.026
cellular sodium ion homeostasisGO:000688340.026
glycine metabolic processGO:000654470.026
purine ribonucleoside catabolic processGO:00461301240.026
angiotensin mediated drinking behaviorGO:000305120.026
artery smooth muscle contractionGO:001482440.025
regulation of cell growthGO:0001558850.025
cell type specific apoptotic processGO:00972851340.025
response to axon injuryGO:0048678590.025
positive regulation of cell deathGO:00109421840.025
response to starvationGO:0042594590.025
growthGO:00400071650.024
small molecule catabolic processGO:0044282590.024
response to monosaccharideGO:00342841590.024
positive regulation of gene expressionGO:00106282440.024
cellular response to oxygen levelsGO:0071453600.024
regulation of extracellular matrix constituent secretionGO:000333020.024
regulation of secretion by cellGO:19035302080.024
response to chromateGO:004668730.024
reproductionGO:00000032450.024
response to vitaminGO:00332731310.024
regulation of reactive oxygen species metabolic processGO:2000377260.024
energy derivation by oxidation of organic compoundsGO:0015980460.024
negative regulation of catalytic activityGO:00430861030.023
single organism reproductive processGO:00447022970.023
hormone secretionGO:00468791150.023
glycogen metabolic processGO:0005977230.023
response to ethanolGO:00454711620.023
response to platinum ionGO:007054140.023
Rat
ribonucleoside triphosphate metabolic processGO:00091991410.023
negative regulation of proteolysisGO:0045861410.023
rhythmic processGO:00485111560.022
Rat
urea cycleGO:000005050.022
neuron differentiationGO:00301823680.022
rna biosynthetic processGO:00327743800.022
central nervous system developmentGO:00074173110.022
purine ribonucleoside monophosphate catabolic processGO:0009169550.022
regulation of transcription dna templatedGO:00063553740.022
divalent metal ion transportGO:00708381320.022
negative regulation of developmental processGO:00510931250.021
tissue regenerationGO:0042246360.021
protein phosphorylationGO:00064683450.021
response to growth factorGO:00708481890.021
ribonucleotide catabolic processGO:00092611360.021
regulation of rna biosynthetic processGO:20011413810.021
negative regulation of serine type endopeptidase activityGO:190000410.021
cellular response to biotic stimulusGO:0071216590.021
alpha amino acid biosynthetic processGO:1901607230.021
protein complex biogenesisGO:00702712630.021
synaptic growth at neuromuscular junctionGO:005112410.021
ribonucleoside metabolic processGO:00091191740.021
glycosyl compound catabolic processGO:19016581260.021
response to hexoseGO:00097461440.021
purine nucleoside monophosphate metabolic processGO:0009126840.021
cellular response to growth factor stimulusGO:00713631620.020
response to oxidative stressGO:00069791860.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
anatomical structure morphogenesisGO:00096532980.020
response to triglycerideGO:003401430.020
cellular glucan metabolic processGO:0006073230.020
regulation of neuron deathGO:19012141150.020
response to ketoneGO:19016541820.020
cellular polysaccharide metabolic processGO:0044264230.020
neuron deathGO:00709971270.020
developmental process involved in reproductionGO:00030061590.020
dephosphorylationGO:0016311980.020
response to dexamethasoneGO:0071548490.020
organonitrogen compound biosynthetic processGO:19015661670.020
carbohydrate metabolic processGO:00059751300.019
peptidyl amino acid modificationGO:00181931260.019
secretion by cellGO:00329402480.019
purine ribonucleotide catabolic processGO:00091541360.019
purine ribonucleoside monophosphate metabolic processGO:0009167840.019
response to zinc ionGO:0010043390.019
regulation of phosphorylationGO:00423252480.019
calcium ion transportGO:00068161310.019
vasculature developmentGO:0001944700.019
regulation of synaptic plasticityGO:0048167700.018
response to glucoseGO:00097491360.018
regulation of ion transportGO:00432692450.018
regulation of hormone levelsGO:00108171870.018
renal system process involved in regulation of systemic arterial blood pressureGO:0003071140.018
response to cytokineGO:00340972150.018
endocrine processGO:0050886320.018
negative regulation of peptidase activityGO:0010466380.018
regulation of lipid metabolic processGO:0019216680.018
response to amino acidGO:0043200750.018
purine nucleoside catabolic processGO:00061521240.018
nucleoside phosphate catabolic processGO:19012921400.017
positive regulation of response to stimulusGO:00485842850.017
Rat
rna metabolic processGO:00160704060.017
response to biotic stimulusGO:00096072260.017
nucleotide metabolic processGO:00091172790.017
steroid biosynthetic processGO:0006694480.017
transcription dna templatedGO:00063513770.017
protein processingGO:0016485680.017
mapk cascadeGO:00001651400.017
cellular response to interferon gammaGO:0071346140.017
carbohydrate catabolic processGO:0016052400.017
nucleoside triphosphate catabolic processGO:00091431230.017
regulation of protein kinase activityGO:00458591050.017
regulation of proteolysisGO:0030162660.016
metal ion homeostasisGO:00550651860.016
negative regulation of phosphate metabolic processGO:0045936800.016
protein secretionGO:0009306340.016
single organism cell adhesionGO:0098602460.016
single organism cellular localizationGO:19025801020.016
cell activationGO:0001775970.016
striated muscle tissue developmentGO:0014706580.016
inflammatory responseGO:00069541500.016
protein complex assemblyGO:00064612630.016
negative regulation of endopeptidase activityGO:0010951360.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
positive regulation of secretionGO:00510471400.016
sexual reproductionGO:00199531480.016
signal transduction by phosphorylationGO:00230141440.015
platelet aggregationGO:007052740.015
regulation of neuron apoptotic processGO:0043523830.015
blood circulationGO:00080151830.015
regulation of peptide transportGO:0090087870.015
positive regulation of rna metabolic processGO:00512542030.015
biological adhesionGO:00226101100.015
atp catabolic processGO:0006200540.015
neuronal action potentialGO:0019228350.015
regulation of intracellular signal transductionGO:19025312180.015
positive regulation of transcription dna templatedGO:00458931970.015
energy reserve metabolic processGO:0006112250.015
regulation of peptidase activityGO:0052547550.015
multicellular organismal reproductive processGO:00486092330.015
metaphase anaphase transition of mitotic cell cycleGO:000709110.015
regulation of rna metabolic processGO:00512523910.015
wound healingGO:00420601220.015
regulation of nervous system developmentGO:00519602640.015
regulation of protein phosphorylationGO:00019321830.014
glucagon secretionGO:007009150.014
single organismal cell cell adhesionGO:0016337420.014
alkaloid metabolic processGO:000982030.014
ribonucleoside catabolic processGO:00424541260.014
regulation of transferase activityGO:00513381230.014
regulation of neuron projection developmentGO:00109751610.014
serine family amino acid metabolic processGO:0009069120.014
signal releaseGO:00230611450.014
cell matrix adhesionGO:0007160190.014
negative regulation of phosphorus metabolic processGO:0010563800.014
circulatory system processGO:00030131830.014
response to lead ionGO:0010288330.014
positive regulation of developmental processGO:00510942830.014
cellular macromolecule catabolic processGO:0044265290.014
regulation of neuronal synaptic plasticityGO:0048168310.014
reactive oxygen species biosynthetic processGO:190340980.014
feeding behaviorGO:0007631530.014
hormone transportGO:00099141210.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
ribose phosphate metabolic processGO:00196932350.014
vesicle mediated transportGO:00161921810.014
pallium developmentGO:0021543420.014
mitotic sister chromatid separationGO:005130610.013
muscle structure developmentGO:0061061870.013
fertilizationGO:000956630.013
positive regulation of gtpase activityGO:0043547470.013
positive regulation of growthGO:0045927550.013
spermatogenesisGO:0007283990.013
agingGO:00075682410.013
purine nucleotide biosynthetic processGO:0006164830.013
sister chromatid segregationGO:000081910.013
hexose metabolic processGO:0019318580.013
dna metabolic processGO:0006259960.013
nucleic acid templated transcriptionGO:00976593790.013
intracellular protein transportGO:0006886790.013
regulation of catabolic processGO:00098941130.013
macromolecule catabolic processGO:0009057580.013
purine ribonucleotide biosynthetic processGO:0009152810.013
organic anion transportGO:00157111320.013
tetrahydrofolate metabolic processGO:004665390.013
regulation of synaptic transmissionGO:00508041410.013
purine nucleotide catabolic processGO:00061951360.013
cellular macromolecular complex assemblyGO:0034622580.013
response to radiationGO:00093141370.013
ion homeostasisGO:00508012120.013
positive regulation of neuron differentiationGO:00456661260.013
regulation of cell adhesionGO:0030155520.012
nitrogen compound transportGO:00717052290.012
negative regulation of cell communicationGO:00106481580.012
regulation of blood pressureGO:0008217830.012
regulation of calcium ion transportGO:0051924770.012
circadian rhythmGO:0007623880.012
Rat
cellular carbohydrate metabolic processGO:0044262720.012
regulation of protein localizationGO:0032880810.012
secretion by tissueGO:0032941370.012
Rat
regulation of kinase activityGO:00435491170.012
positive regulation of peptide secretionGO:0002793520.012
multicellular organism growthGO:003526410.012
cellular response to hypoxiaGO:0071456510.012
cellular macromolecule localizationGO:00707271220.012
negative regulation of hydrolase activityGO:0051346520.012
regulation of neuron differentiationGO:00456642080.012
synaptic transmissionGO:00072682350.012
negative regulation of serine type peptidase activityGO:190257210.012
multicellular organismal signalingGO:0035637440.012
single organism intracellular transportGO:19025821660.012
regulation of homeostatic processGO:00328441010.012
negative regulation of fibrinolysisGO:005191820.012
anion transportGO:00068201780.012
cellular response to campGO:0071320260.012
positive regulation of cellular component organizationGO:00511302000.012
peptidyl tyrosine modificationGO:0018212720.012
vasoconstrictionGO:0042310540.012
positive regulation of hemostasisGO:190004840.012
response to interleukin 1GO:0070555550.012
nucleoside catabolic processGO:00091641260.012
negative regulation of transportGO:00510511360.012
regulation of protein transportGO:0051223680.012
proteolysis involved in cellular protein catabolic processGO:0051603190.012
carbohydrate derivative biosynthetic processGO:19011371240.011
epithelium developmentGO:0060429960.011
nucleotide catabolic processGO:00091661390.011
negative regulation of response to stimulusGO:00485851550.011
g protein coupled receptor signaling pathwayGO:00071862420.011
regulation of anatomical structure morphogenesisGO:00226031410.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
cellular metal ion homeostasisGO:00068751720.011
cofactor metabolic processGO:0051186950.011
reactive nitrogen species metabolic processGO:200105710.011
positive regulation of homeostatic processGO:0032846490.011
nucleocytoplasmic transportGO:0006913480.011
oxidation reduction processGO:00551143040.011
head developmentGO:00603222470.011
negative regulation of nervous system developmentGO:0051961790.011
cellular protein complex assemblyGO:0043623440.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
plasminogen activationGO:003163920.011
organic hydroxy compound transportGO:0015850770.011
response to mercury ionGO:0046689150.011
Rat
glucan metabolic processGO:0044042230.011
negative regulation of biomineral tissue developmentGO:007016820.011
development of primary sexual characteristicsGO:00451371070.011
cellular response to hexose stimulusGO:0071331650.011
negative regulation of protein phosphorylationGO:0001933440.011
regulation of cell cell adhesionGO:0022407140.011
positive regulation of programmed cell deathGO:00430681570.011
coenzyme metabolic processGO:0006732860.011
cytoplasmic transportGO:00164821150.011
positive regulation of cell growthGO:0030307440.011
cellular response to monosaccharide stimulusGO:0071326670.011
peptide transportGO:0015833970.011
urea metabolic processGO:001962750.011
regulation of tube sizeGO:0035150890.011
epithelial cell differentiationGO:0030855710.010
polysaccharide metabolic processGO:0005976250.010
positive regulation of heterotypic cell cell adhesionGO:003411610.010
negative regulation of cellular amine metabolic processGO:003323930.010
negative regulation of cellular component organizationGO:0051129830.010
male gamete generationGO:0048232990.010
response to temperature stimulusGO:0009266940.010
behaviorGO:00076102050.010
Rat
single organism organelle organizationGO:19025891800.010
cellular modified amino acid metabolic processGO:0006575610.010
purine nucleoside monophosphate catabolic processGO:0009128550.010
negative regulation of cell cycle phase transitionGO:190198840.010
regulation of dna metabolic processGO:0051052600.010
regulation of protein serine threonine kinase activityGO:0071900640.010
salivary gland developmentGO:000743130.010

Afp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.033
vascular diseaseDOID:17800.028
artery diseaseDOID:005082800.028
disease of anatomical entityDOID:700.028
cardiovascular system diseaseDOID:128700.028
inherited metabolic disorderDOID:65500.018
acquired metabolic diseaseDOID:006015800.014