Rattus norvegicus

36 known processes

Crem

cAMP responsive element modulator

(Aliases: Icer)

Crem biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate derivative metabolic processGO:19011353460.176
Mouse
response to temperature stimulusGO:0009266940.170
response to extracellular stimulusGO:00099913800.155
cellular amino acid metabolic processGO:00065201070.118
carboxylic acid metabolic processGO:00197522890.118
response to peptideGO:19016522920.105
oxoacid metabolic processGO:00434362900.088
purine containing compound metabolic processGO:00725212530.087
organophosphate metabolic processGO:00196373700.080
organic substance catabolic processGO:19015753160.079
single organism catabolic processGO:00447122830.075
response to molecule of bacterial originGO:00022371940.074
secretionGO:00469033070.072
response to nutrientGO:00075842480.071
catabolic processGO:00090563510.070
nucleobase containing small molecule metabolic processGO:00550863160.066
cellular response to oxygen containing compoundGO:19017013860.065
blood circulationGO:00080151830.061
response to peptide hormoneGO:00434342780.059
single organism biosynthetic processGO:00447113420.059
regulation of molecular functionGO:00650093980.056
negative regulation of programmed cell deathGO:00430691830.055
positive regulation of cellular component movementGO:00512721020.054
ribonucleotide metabolic processGO:00092592310.054
response to cytokineGO:00340972150.052
cellular response to endogenous stimulusGO:00714953770.050
Rat
purine nucleotide metabolic processGO:00061632290.049
regulation of programmed cell deathGO:00430673410.049
Rat
response to estrogenGO:00436272320.049
secretion by cellGO:00329402480.048
regulation of cellular component organizationGO:00511283680.048
Rat
response to nutrient levelsGO:00316673700.047
chemical homeostasisGO:00488782920.047
cellular lipid metabolic processGO:00442552080.047
response to estradiolGO:00323551640.046
hormone secretionGO:00468791150.046
positive regulation of catalytic activityGO:00430851840.046
signal releaseGO:00230611450.046
regulation of secretion by cellGO:19035302080.046
cellular amine metabolic processGO:0044106380.044
positive regulation of phosphorus metabolic processGO:00105622620.044
response to glucocorticoidGO:00513842230.044
cellular catabolic processGO:00442482950.044
nucleoside phosphate metabolic processGO:00067532830.044
homeostatic processGO:00425923310.043
ribose phosphate metabolic processGO:00196932350.043
organic acid metabolic processGO:00060822920.043
nucleotide metabolic processGO:00091172790.043
regulation of hormone secretionGO:00468831060.042
cellular modified amino acid metabolic processGO:0006575610.042
cellular response to stressGO:00335542690.042
g protein coupled receptor signaling pathwayGO:00071862420.042
purine ribonucleotide metabolic processGO:00091502270.041
regulation of catalytic activityGO:00507903040.041
response to corticosteroidGO:00319602350.040
response to organophosphorusGO:00466831020.040
Mouse
cellular chemical homeostasisGO:00550822470.040
cellular ion homeostasisGO:00068731840.039
alpha amino acid metabolic processGO:1901605710.039
amine metabolic processGO:0009308380.039
response to inorganic substanceGO:00100353770.039
Rat
programmed cell deathGO:00125013920.039
Rat
nucleoside metabolic processGO:00091161790.038
regenerationGO:00310991630.038
regulation of apoptotic processGO:00429813350.038
Rat
regulation of secretionGO:00510462240.037
regulation of phosphorus metabolic processGO:00511743490.037
cell cell signalingGO:00072673350.037
lipid metabolic processGO:00066292830.036
regulation of nucleic acid templated transcriptionGO:19035063800.035
Human Mouse Rat
positive regulation of multicellular organismal processGO:00512403870.035
Rat
regulation of rna metabolic processGO:00512523910.035
Human Mouse Rat
negative regulation of cellular metabolic processGO:00313242810.034
Mouse
regulation of nucleotide metabolic processGO:00061401170.034
single organism reproductive processGO:00447022970.033
Mouse
nucleic acid templated transcriptionGO:00976593790.033
Human Mouse Rat
cellular homeostasisGO:00197252520.033
reproductive processGO:00224143720.033
Mouse
nucleotide catabolic processGO:00091661390.033
glycerolipid metabolic processGO:0046486670.032
circulatory system processGO:00030131830.032
agingGO:00075682410.032
neuron developmentGO:00486662860.031
Rat
negative regulation of cell deathGO:00605482290.031
cellular ketone metabolic processGO:0042180510.031
multicellular organism reproductionGO:00325042330.031
Mouse
regulation of cellular catabolic processGO:00313291010.030
regulation of phosphate metabolic processGO:00192203490.030
neurological system processGO:00508772190.030
response to ketoneGO:19016541820.030
retina morphogenesis in camera type eyeGO:006004210.030
response to heatGO:0009408600.030
positive regulation of developmental processGO:00510942830.030
Rat
organ regenerationGO:00311001010.030
response to metal ionGO:00100382530.030
Rat
regulation of intracellular signal transductionGO:19025312180.029
regulation of rna biosynthetic processGO:20011413810.029
Human Mouse Rat
nucleobase containing compound catabolic processGO:00346551520.029
hormone transportGO:00099141210.029
carbohydrate metabolic processGO:00059751300.029
sulfur compound metabolic processGO:0006790700.029
response to lipopolysaccharideGO:00324961910.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.028
response to oxygen levelsGO:00704822650.028
signal transduction by phosphorylationGO:00230141440.028
apoptotic processGO:00069153810.028
Rat
organonitrogen compound biosynthetic processGO:19015661670.027
regulation of catabolic processGO:00098941130.027
cellular metal ion homeostasisGO:00068751720.027
peptide secretionGO:0002790860.027
transcription from rna polymerase ii promoterGO:00063662520.027
Mouse Rat
purine ribonucleotide catabolic processGO:00091541360.027
neuron deathGO:00709971270.026
glycosyl compound metabolic processGO:19016571820.026
purine nucleoside metabolic processGO:00422781690.026
negative regulation of macromolecule metabolic processGO:00106052600.026
Mouse
intracellular signal transductionGO:00355563140.026
negative regulation of signalingGO:00230571570.026
carbohydrate derivative catabolic processGO:19011361470.026
monocarboxylic acid metabolic processGO:00327871520.026
regulation of nervous system developmentGO:00519602640.026
Rat
peptide hormone secretionGO:0030072840.026
female pregnancyGO:00075651220.026
positive regulation of nitrogen compound metabolic processGO:00511733340.025
Mouse Rat
response to woundingGO:00096112540.025
regulation of kinase activityGO:00435491170.025
regulation of phosphorylationGO:00423252480.025
positive regulation of cellular component organizationGO:00511302000.025
Rat
negative regulation of apoptotic processGO:00430661810.024
monosaccharide metabolic processGO:0005996610.024
purine ribonucleoside triphosphate catabolic processGO:00092071220.024
response to radiationGO:00093141370.023
heterocycle catabolic processGO:00467001670.023
regulation of protein metabolic processGO:00512462890.023
regulation of signal transductionGO:00099663180.023
response to insulinGO:00328681330.023
nitrogen compound transportGO:00717052290.023
purine ribonucleoside metabolic processGO:00461281680.023
behaviorGO:00076102050.023
response to coldGO:0009409290.023
multicellular organism growthGO:003526410.022
cell migrationGO:00164771970.022
response to vitaminGO:00332731310.022
negative regulation of metabolic processGO:00098923310.022
Mouse
regulation of cellular amino acid metabolic processGO:000652120.022
regulation of system processGO:00440572080.022
response to oxidative stressGO:00069791860.022
coenzyme metabolic processGO:0006732860.022
organonitrogen compound catabolic processGO:19015651790.022
organic hydroxy compound metabolic processGO:19016151150.022
regulation of cell differentiationGO:00455953200.022
Rat
purine nucleotide catabolic processGO:00061951360.022
regulation of peptide hormone secretionGO:0090276800.022
regulation of peptide secretionGO:0002791820.022
nucleoside phosphate catabolic processGO:19012921400.021
multi organism reproductive processGO:00447032620.021
Mouse
organophosphate catabolic processGO:00464341480.021
regulation of anatomical structure sizeGO:00900661350.021
protein complex biogenesisGO:00702712630.021
Rat
regulation of cellular ketone metabolic processGO:0010565270.021
regulation of insulin secretionGO:0050796650.021
lipid biosynthetic processGO:00086101280.021
cellular component biogenesisGO:00440853680.021
Rat
eye morphogenesisGO:004859240.021
cellular component assemblyGO:00226073600.020
Rat
positive regulation of response to stimulusGO:00485842850.020
rhythmic processGO:00485111560.020
dephosphorylationGO:0016311980.020
regulation of purine nucleotide metabolic processGO:19005421150.020
ribonucleoside metabolic processGO:00091191740.020
regulation of peptide transportGO:0090087870.020
cellular cation homeostasisGO:00300031800.020
negative regulation of cell communicationGO:00106481580.020
calcium ion homeostasisGO:00550741620.020
response to biotic stimulusGO:00096072260.019
macromolecular complex assemblyGO:00650032730.019
Rat
divalent inorganic cation homeostasisGO:00725071650.019
regulation of cellular amine metabolic processGO:003323880.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
Mouse Rat
cofactor metabolic processGO:0051186950.019
negative regulation of signal transductionGO:0009968830.019
regulation of hydrolase activityGO:00513361430.019
positive regulation of secretionGO:00510471400.019
regulation of multicellular organismal developmentGO:20000263760.019
Rat
response to purine containing compoundGO:00140741260.019
Mouse
cell projection organizationGO:00300303020.019
Rat
regulation of cell developmentGO:00602842630.019
Rat
cellular response to nitrogen compoundGO:19016992100.019
carbohydrate derivative biosynthetic processGO:19011371240.019
membrane organizationGO:0061024940.019
response to external biotic stimulusGO:00432072210.019
regulation of neuron projection developmentGO:00109751610.018
Rat
regulation of cellular localizationGO:00603412630.018
vesicle mediated transportGO:00161921810.018
protein phosphorylationGO:00064683450.018
cellular calcium ion homeostasisGO:00068741600.018
response to gamma radiationGO:0010332240.018
response to monosaccharideGO:00342841590.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
Mouse
positive regulation of cell differentiationGO:00455972170.018
Rat
regulation of neurogenesisGO:00507672470.018
Rat
multicellular organismal reproductive processGO:00486092330.018
Mouse
immune system processGO:00023762040.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
lipid storageGO:001991510.018
regulation of neuron deathGO:19012141150.018
positive regulation of phosphate metabolic processGO:00459372620.018
ion homeostasisGO:00508012120.018
positive regulation of nervous system developmentGO:00519621780.018
Rat
cellular response to peptideGO:19016531330.018
positive regulation of biosynthetic processGO:00098913190.018
Mouse Rat
regulation of tube sizeGO:0035150890.017
glucose metabolic processGO:0006006520.017
jak stat cascadeGO:0007259260.017
positive regulation of neurogenesisGO:00507691650.017
Rat
regulation of hormone levelsGO:00108171870.017
positive regulation of nucleotide metabolic processGO:0045981910.017
regulation of protein phosphorylationGO:00019321830.017
insulin secretionGO:0030073690.017
organic cyclic compound catabolic processGO:19013611750.017
regulation of cell projection organizationGO:00313441750.017
Rat
locomotionGO:00400112370.017
response to calcium ionGO:0051592590.017
macromolecular complex subunit organizationGO:00439333390.017
Rat
positive regulation of neuron projection developmentGO:0010976990.017
Rat
response to bacteriumGO:00096172000.017
anatomical structure morphogenesisGO:00096532980.017
neuron projection developmentGO:00311752730.017
Rat
metal ion homeostasisGO:00550651860.016
response to other organismGO:00517072200.016
cellular nitrogen compound catabolic processGO:00442701630.016
localization of cellGO:00516742020.016
central nervous system developmentGO:00074173110.016
pyruvate metabolic processGO:0006090270.016
response to carbohydrateGO:00097431830.016
regulation of mapk cascadeGO:00434081160.016
aromatic compound catabolic processGO:00194391680.016
cellular response to organonitrogen compoundGO:00714171970.016
reproductionGO:00000032450.016
Mouse
response to foodGO:0032094270.016
positive regulation of molecular functionGO:00440932300.016
tissue developmentGO:00098882520.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
Rat
cellular response to insulin stimulusGO:0032869810.016
regulation of homeostatic processGO:00328441010.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of phosphorylationGO:00423271770.015
t cell receptor signaling pathwayGO:005085210.015
gtp metabolic processGO:0046039720.015
response to hypoxiaGO:00016662310.015
cellular amino acid biosynthetic processGO:0008652320.015
circadian rhythmGO:0007623880.015
growthGO:00400071650.015
protein complex subunit organizationGO:00718223020.015
Rat
circulatory system developmentGO:00723591340.015
regulation of cellular protein metabolic processGO:00322682670.015
response to hexoseGO:00097461440.015
sexual reproductionGO:00199531480.015
Mouse
brain developmentGO:00074202470.015
regulation of transferase activityGO:00513381230.015
response to glucoseGO:00097491360.015
regulation of neuron differentiationGO:00456642080.015
Rat
negative regulation of molecular functionGO:00440921330.015
neuron differentiationGO:00301823680.015
Rat
gland developmentGO:00487321550.015
vascular process in circulatory systemGO:0003018960.015
response to decreased oxygen levelsGO:00362932370.014
cellular component movementGO:00069282480.014
camp metabolic processGO:0046058630.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
oxidation reduction processGO:00551143040.014
reactive oxygen species biosynthetic processGO:190340980.014
protein complex assemblyGO:00064612630.014
Rat
purine nucleoside triphosphate catabolic processGO:00091461220.014
regulation of protein modification processGO:00313991940.014
cardiovascular system developmentGO:00723581340.014
cytokine mediated signaling pathwayGO:0019221430.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
Mouse Rat
cellular response to hormone stimulusGO:00328702470.014
amide transportGO:00428861050.014
positive regulation of neuron differentiationGO:00456661260.014
Rat
carbohydrate homeostasisGO:0033500750.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
metal ion transportGO:00300012890.014
positive regulation of cell proliferationGO:00082842490.014
hexose metabolic processGO:0019318580.013
vasculature developmentGO:0001944700.013
muscle structure developmentGO:0061061870.013
organophosphate biosynthetic processGO:00904071430.013
camera type eye morphogenesisGO:004859320.013
transcription dna templatedGO:00063513770.013
Human Mouse Rat
cell part morphogenesisGO:00329901230.013
regulation of protein kinase activityGO:00458591050.013
cellular response to growth factor stimulusGO:00713631620.013
Rat
cellular response to cytokine stimulusGO:00713451270.013
positive regulation of cell communicationGO:00106472710.013
negative regulation of multicellular organismal processGO:00512412030.013
ribonucleotide catabolic processGO:00092611360.013
inflammatory responseGO:00069541500.013
regulation of neuron apoptotic processGO:0043523830.012
regulation of lipid metabolic processGO:0019216680.012
positive regulation of locomotionGO:00400171020.012
positive regulation of cellular biosynthetic processGO:00313282950.012
Mouse Rat
positive regulation of catabolic processGO:0009896780.012
macromolecule localizationGO:00330362520.012
response to acid chemicalGO:00011012220.012
regulation of fat cell differentiationGO:004559830.012
antigen receptor mediated signaling pathwayGO:005085110.012
negative regulation of response to stimulusGO:00485851550.012
purine containing compound catabolic processGO:00725231380.012
cellular response to alcoholGO:0097306870.012
positive regulation of cell developmentGO:00107201760.012
Rat
single organism carbohydrate metabolic processGO:00447231180.012
regulation of lipid biosynthetic processGO:0046890380.012
carbohydrate catabolic processGO:0016052400.012
regulation of nucleotide catabolic processGO:0030811650.012
negative regulation of neuron deathGO:1901215690.012
negative regulation of developmental processGO:00510931250.012
positive regulation of apoptotic processGO:00430651540.012
cyclic nucleotide metabolic processGO:0009187800.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
positive regulation of cell deathGO:00109421840.012
organelle organizationGO:00069962660.012
positive regulation of immune system processGO:0002684900.012
phospholipid metabolic processGO:0006644610.012
regulation of cell motilityGO:20001451310.012
response to starvationGO:0042594590.012
cell motilityGO:00488702020.012
negative regulation of catalytic activityGO:00430861030.012
negative regulation of protein metabolic processGO:00512481140.012
response to growth factorGO:00708481890.012
Rat
sulfur compound biosynthetic processGO:0044272190.012
glucose homeostasisGO:0042593750.012
cellular response to extracellular stimulusGO:0031668730.012
guanosine containing compound catabolic processGO:1901069710.012
positive regulation of intracellular signal transductionGO:19025331380.011
positive regulation of cell projection organizationGO:00313461110.011
Rat
regulation of blood vessel sizeGO:0050880890.011
spermatogenesisGO:0007283990.011
Mouse
transmembrane transportGO:00550854120.011
purine containing compound biosynthetic processGO:0072522850.011
multi multicellular organism processGO:00447061380.011
negative regulation of neuron apoptotic processGO:0043524450.011
gtp catabolic processGO:0006184710.011
positive regulation of transcription dna templatedGO:00458931970.011
Mouse Rat
gamete generationGO:00072761240.011
Mouse
nucleoside triphosphate catabolic processGO:00091431230.011
response to ionizing radiationGO:0010212590.011
sensory organ developmentGO:0007423740.011
cellular amide metabolic processGO:0043603440.011
sensory perceptionGO:00076001010.011
head developmentGO:00603222470.011
cytosolic calcium ion homeostasisGO:00514801400.011
positive regulation of secretion by cellGO:19035321280.011
response to campGO:0051591910.011
Mouse
positive regulation of nucleoside metabolic processGO:0045979550.011
synaptic transmissionGO:00072682350.011
response to amino acidGO:0043200750.011
cellular carbohydrate metabolic processGO:0044262720.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
Mouse
positive regulation of rna metabolic processGO:00512542030.010
Mouse Rat
cellular response to external stimulusGO:00714961180.010
photoperiodismGO:000964840.010
reactive oxygen species metabolic processGO:0072593370.010
dna metabolic processGO:0006259960.010
Rat
rna biosynthetic processGO:00327743800.010
Human Mouse Rat
single organism organelle organizationGO:19025891800.010
glycerophospholipid metabolic processGO:0006650470.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
protein oligomerizationGO:00512591910.010
defense responseGO:00069521940.010
cellular component morphogenesisGO:00329891550.010
cellular response to lipidGO:00713962010.010
regulation of cell proliferationGO:00421273590.010
sleepGO:0030431300.010
purine nucleoside catabolic processGO:00061521240.010

Crem disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.043
inherited metabolic disorderDOID:65500.043
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013