IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Mars

methionine-tRNA synthetase

Entrez: 299851
RGD: 1305321
Ensembl: ENSRNOG00000025459
UniProtKB: D3Z941

Process Predictions
Disease Predictions

Mars biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
trna aminoacylation	GO:0043039	3	0.727
trna metabolic process	GO:0006399	4	0.515
trna aminoacylation for protein translation	GO:0006418	3	0.498
amino acid activation	GO:0043038	3	0.484
mitochondrial rna metabolic process	GO:0000959	1	0.137
cellular amino acid metabolic process	GO:0006520	107	0.136
regulation of protein metabolic process	GO:0051246	289	0.128
organic acid metabolic process	GO:0006082	292	0.120
carboxylic acid metabolic process	GO:0019752	289	0.084
organophosphate metabolic process	GO:0019637	370	0.078
alpha amino acid biosynthetic process	GO:1901607	23	0.075
rna metabolic process	GO:0016070	406	0.072
regulation of cellular protein metabolic process	GO:0032268	267	0.071
nucleoside phosphate metabolic process	GO:0006753	283	0.068
ncrna metabolic process	GO:0034660	8	0.067
nucleobase containing small molecule metabolic process	GO:0055086	316	0.064
single organism biosynthetic process	GO:0044711	342	0.059
nucleoside phosphate biosynthetic process	GO:1901293	102	0.058
oxoacid metabolic process	GO:0043436	290	0.057
purine containing compound metabolic process	GO:0072521	253	0.053
nucleotide metabolic process	GO:0009117	279	0.050
alpha amino acid metabolic process	GO:1901605	71	0.048
translation	GO:0006412	35	0.039
apoptotic process	GO:0006915	381	0.039
organelle organization	GO:0006996	266	0.038
organophosphate biosynthetic process	GO:0090407	143	0.038
organonitrogen compound biosynthetic process	GO:1901566	167	0.038
ribose phosphate metabolic process	GO:0019693	235	0.037
double strand break repair	GO:0006302	1	0.037
glycosyl compound metabolic process	GO:1901657	182	0.037
cellular response to stress	GO:0033554	269	0.034
vesicle mediated transport	GO:0016192	181	0.033
carbohydrate derivative metabolic process	GO:1901135	346	0.033
regulation of programmed cell death	GO:0043067	341	0.032
purine nucleotide metabolic process	GO:0006163	229	0.032
head development	GO:0060322	247	0.032
programmed cell death	GO:0012501	392	0.030
single organism reproductive process	GO:0044702	297	0.028
central nervous system development	GO:0007417	311	0.028
regulation of apoptotic process	GO:0042981	335	0.028
ribonucleotide metabolic process	GO:0009259	231	0.028
cellular amino acid biosynthetic process	GO:0008652	32	0.027
cellular catabolic process	GO:0044248	295	0.027
immune system process	GO:0002376	204	0.026
nucleoside metabolic process	GO:0009116	179	0.026
cation transport	GO:0006812	382	0.025
defense response	GO:0006952	194	0.025
ribonucleoside metabolic process	GO:0009119	174	0.024
reproductive process	GO:0022414	372	0.024
hair follicle development	GO:0001942	2	0.024
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.023
dna metabolic process	GO:0006259	96	0.023
ribonucleotide biosynthetic process	GO:0009260	85	0.023
positive regulation of biosynthetic process	GO:0009891	319	0.023
amine metabolic process	GO:0009308	38	0.022
cellular amine metabolic process	GO:0044106	38	0.022
purine nucleoside metabolic process	GO:0042278	169	0.022
negative regulation of macromolecule metabolic process	GO:0010605	260	0.021
purine ribonucleotide metabolic process	GO:0009150	227	0.021
regulation of phosphate metabolic process	GO:0019220	349	0.021
brain development	GO:0007420	247	0.021
cellular component biogenesis	GO:0044085	368	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.021
catabolic process	GO:0009056	351	0.020
negative regulation of multicellular organismal process	GO:0051241	203	0.020
regulation of phosphorus metabolic process	GO:0051174	349	0.020
positive regulation of multicellular organismal process	GO:0051240	387	0.020
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019
neurological system process	GO:0050877	219	0.019
purine nucleoside catabolic process	GO:0006152	124	0.018
mitochondrion organization	GO:0007005	35	0.018
multi organism reproductive process	GO:0044703	262	0.018
regulation of phosphorylation	GO:0042325	248	0.018
coenzyme metabolic process	GO:0006732	86	0.017
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.017
organonitrogen compound catabolic process	GO:1901565	179	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.017
purine ribonucleotide biosynthetic process	GO:0009152	81	0.017
cellular response to topologically incorrect protein	GO:0035967	3	0.017
homeostatic process	GO:0042592	331	0.017
positive regulation of protein metabolic process	GO:0051247	178	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.016
epithelium development	GO:0060429	96	0.016
response to nutrient levels	GO:0031667	370	0.016
regulation of rna metabolic process	GO:0051252	391	0.016
response to biotic stimulus	GO:0009607	226	0.016
organic acid biosynthetic process	GO:0016053	83	0.016
ion transmembrane transport	GO:0034220	365	0.016
ribose phosphate biosynthetic process	GO:0046390	87	0.016
circulatory system development	GO:0072359	134	0.016
rna biosynthetic process	GO:0032774	380	0.015
regulation of neuron apoptotic process	GO:0043523	83	0.015
protein phosphorylation	GO:0006468	345	0.015
circulatory system process	GO:0003013	183	0.015
multicellular organismal reproductive process	GO:0048609	233	0.015
regulation of multicellular organismal development	GO:2000026	376	0.015
intracellular transport	GO:0046907	185	0.015
heterocycle catabolic process	GO:0046700	167	0.015
ncrna processing	GO:0034470	3	0.015
neuron death	GO:0070997	127	0.015
reproduction	GO:0000003	245	0.015
purine containing compound catabolic process	GO:0072523	138	0.015
response to external biotic stimulus	GO:0043207	221	0.014
carbohydrate derivative biosynthetic process	GO:1901137	124	0.014
macromolecular complex subunit organization	GO:0043933	339	0.014
monovalent inorganic cation transport	GO:0015672	172	0.014
response to other organism	GO:0051707	220	0.014
neuromuscular process	GO:0050905	2	0.014
purine containing compound biosynthetic process	GO:0072522	85	0.014
nucleotide biosynthetic process	GO:0009165	98	0.014
positive regulation of developmental process	GO:0051094	283	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
cell cycle	GO:0007049	101	0.014
intracellular signal transduction	GO:0035556	314	0.014
regulation of system process	GO:0044057	208	0.014
molting cycle process	GO:0022404	2	0.014
multi multicellular organism process	GO:0044706	138	0.014
nucleoside monophosphate metabolic process	GO:0009123	93	0.014
sexual reproduction	GO:0019953	148	0.014
nucleobase containing compound catabolic process	GO:0034655	152	0.013
gamete generation	GO:0007276	124	0.013
transcription dna templated	GO:0006351	377	0.013
positive regulation of gene expression	GO:0010628	244	0.013
organic cyclic compound catabolic process	GO:1901361	175	0.013
hair cycle process	GO:0022405	2	0.013
purine ribonucleoside biosynthetic process	GO:0046129	21	0.013
blood circulation	GO:0008015	183	0.013
single organism intracellular transport	GO:1902582	166	0.013
regulation of cell differentiation	GO:0045595	320	0.013
chemical homeostasis	GO:0048878	292	0.012
protein localization	GO:0008104	191	0.012
anion transport	GO:0006820	178	0.012
aromatic compound catabolic process	GO:0019439	168	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
positive regulation of molecular function	GO:0044093	230	0.012
metal ion transport	GO:0030001	289	0.012
positive regulation of apoptotic process	GO:0043065	154	0.012
negative regulation of developmental process	GO:0051093	125	0.012
response to inorganic substance	GO:0010035	377	0.012
muscle system process	GO:0003012	115	0.012
regulation of ion transport	GO:0043269	245	0.012
reproductive system development	GO:0061458	128	0.012
regulation of cell development	GO:0060284	263	0.012
positive regulation of phosphate metabolic process	GO:0045937	262	0.012
transmembrane transport	GO:0055085	412	0.012
regulation of intracellular signal transduction	GO:1902531	218	0.012
regulation of cell cycle	GO:0051726	73	0.012
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
protein complex assembly	GO:0006461	263	0.011
response to starvation	GO:0042594	59	0.011
negative regulation of cellular metabolic process	GO:0031324	281	0.011
single organism organelle organization	GO:1902589	180	0.011
secretion	GO:0046903	307	0.011
regulation of molecular function	GO:0065009	398	0.011
carboxylic acid biosynthetic process	GO:0046394	83	0.011
cardiovascular system development	GO:0072358	134	0.011
cofactor metabolic process	GO:0051186	95	0.011
cellular macromolecular complex assembly	GO:0034622	58	0.011
macromolecule localization	GO:0033036	252	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
negative regulation of neuron death	GO:1901215	69	0.011
secretion by cell	GO:0032940	248	0.011
cellular response to oxygen containing compound	GO:1901701	386	0.011
organophosphate catabolic process	GO:0046434	148	0.011
cellular ketone metabolic process	GO:0042180	51	0.011
cellular nitrogen compound catabolic process	GO:0044270	163	0.011
response to extracellular stimulus	GO:0009991	380	0.011
regulation of neurogenesis	GO:0050767	247	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.011
purine ribonucleoside metabolic process	GO:0046128	168	0.011
cytokine biosynthetic process	GO:0042089	3	0.011
cellular response to unfolded protein	GO:0034620	2	0.010
positive regulation of cellular protein metabolic process	GO:0032270	167	0.010
purine ribonucleoside catabolic process	GO:0046130	124	0.010
response to acid chemical	GO:0001101	222	0.010
hepaticobiliary system development	GO:0061008	90	0.010
protein transport	GO:0015031	132	0.010
centrosome organization	GO:0051297	1	0.010
regulation of cell proliferation	GO:0042127	359	0.010
cellular component assembly	GO:0022607	360	0.010
regulation of protein modification process	GO:0031399	194	0.010

Mars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.196
charcot marie tooth disease	DOID:10595	0.196
disease of anatomical entity	DOID:7	0.196
neuromuscular disease	DOID:440	0.196
neuropathy	DOID:870	0.196
central nervous system disease	DOID:331	0.032
disease of cellular proliferation	DOID:14566	0.011

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