Rattus norvegicus

109 known processes

Pou1f1

POU class 1 homeobox 1

(Aliases: Pit1,GHF1A,PIT1Z,GHF1)

Pou1f1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to oxygen levelsGO:00704822650.330
regulation of programmed cell deathGO:00430673410.311
cellular response to hormone stimulusGO:00328702470.297
regulation of system processGO:00440572080.245
cellular response to endogenous stimulusGO:00714953770.240
growthGO:00400071650.222
Mouse
cellular response to lipidGO:00713962010.219
negative regulation of cell deathGO:00605482290.200
response to external biotic stimulusGO:00432072210.197
oxoacid metabolic processGO:00434362900.189
regulation of phosphate metabolic processGO:00192203490.165
Mouse
response to glucocorticoidGO:00513842230.165
apoptotic processGO:00069153810.157
response to peptideGO:19016522920.155
programmed cell deathGO:00125013920.153
response to extracellular stimulusGO:00099913800.150
cellular response to organic cyclic compoundGO:00714072020.150
negative regulation of cell proliferationGO:00082851190.138
protein phosphorylationGO:00064683450.136
response to biotic stimulusGO:00096072260.134
regulation of cell proliferationGO:00421273590.130
Mouse
response to other organismGO:00517072200.129
response to decreased oxygen levelsGO:00362932370.128
regulation of cellular protein metabolic processGO:00322682670.127
response to nutrientGO:00075842480.126
nitrogen compound transportGO:00717052290.125
cellular response to oxygen containing compoundGO:19017013860.125
intracellular signal transductionGO:00355563140.123
response to metal ionGO:00100382530.122
response to estrogenGO:00436272320.117
regulation of signal transductionGO:00099663180.110
Mouse
response to peptide hormoneGO:00434342780.109
regulation of phosphorus metabolic processGO:00511743490.108
Mouse
single organism biosynthetic processGO:00447113420.104
Mouse
regulation of hormone levelsGO:00108171870.100
response to inorganic substanceGO:00100353770.099
response to molecule of bacterial originGO:00022371940.098
protein complex subunit organizationGO:00718223020.098
response to acid chemicalGO:00011012220.096
positive regulation of biosynthetic processGO:00098913190.093
carboxylic acid metabolic processGO:00197522890.092
gland developmentGO:00487321550.091
cellular response to corticosteroid stimulusGO:0071384690.088
response to hypoxiaGO:00016662310.085
circadian rhythmGO:0007623880.085
cellular response to alcoholGO:0097306870.084
calcium ion importGO:0070509220.083
response to estradiolGO:00323551640.082
regulation of apoptotic processGO:00429813350.082
negative regulation of metabolic processGO:00098923310.081
rhythmic processGO:00485111560.080
regulation of blood circulationGO:19035221100.079
cellular amino acid metabolic processGO:00065201070.078
cell cell signalingGO:00072673350.077
regulation of secretion by cellGO:19035302080.076
regulation of protein metabolic processGO:00512462890.075
response to cytokineGO:00340972150.074
response to nutrient levelsGO:00316673700.074
signal releaseGO:00230611450.073
response to bacteriumGO:00096172000.072
organic acid metabolic processGO:00060822920.072
response to corticosteroidGO:00319602350.071
cellular response to organonitrogen compoundGO:00714171970.071
regulation of protein modification processGO:00313991940.070
reproductive processGO:00224143720.069
Rat
positive regulation of nervous system developmentGO:00519621780.066
positive regulation of cellular biosynthetic processGO:00313282950.065
macromolecular complex assemblyGO:00650032730.065
regulation of epithelial cell proliferationGO:0050678490.065
positive regulation of response to stimulusGO:00485842850.065
agingGO:00075682410.063
Mouse
secretion by cellGO:00329402480.063
positive regulation of neurogenesisGO:00507691650.063
positive regulation of multicellular organismal processGO:00512403870.063
Mouse
macromolecule localizationGO:00330362520.062
regulation of cell developmentGO:00602842630.060
homeostatic processGO:00425923310.060
cellular component biogenesisGO:00440853680.059
regulation of metal ion transportGO:00109591180.059
positive regulation of phosphate metabolic processGO:00459372620.058
Mouse
neurological system processGO:00508772190.057
negative regulation of apoptotic processGO:00430661810.057
regulation of cellular localizationGO:00603412630.056
signal transduction by phosphorylationGO:00230141440.055
cellular response to stressGO:00335542690.054
positive regulation of cell developmentGO:00107201760.053
transcription dna templatedGO:00063513770.053
regulation of secretionGO:00510462240.053
epithelial cell proliferationGO:0050673540.053
circulatory system processGO:00030131830.052
amide transportGO:00428861050.052
regulation of phosphorylationGO:00423252480.051
cellular response to nitrogen compoundGO:19016992100.051
multi organism reproductive processGO:00447032620.051
Rat
multi multicellular organism processGO:00447061380.051
regulation of anatomical structure sizeGO:00900661350.050
secretionGO:00469033070.050
positive regulation of cell differentiationGO:00455972170.048
cellular ketone metabolic processGO:0042180510.047
cellular response to peptideGO:19016531330.046
blood circulationGO:00080151830.045
positive regulation of transportGO:00510502450.044
renal system developmentGO:0072001670.044
positive regulation of cell communicationGO:00106472710.044
regulation of protein phosphorylationGO:00019321830.043
steroid metabolic processGO:0008202730.043
synaptic transmissionGO:00072682350.042
negative regulation of gene expressionGO:00106291990.041
regulation of molecular functionGO:00650093980.041
response to calcium ionGO:0051592590.041
heart contractionGO:0060047570.040
regenerationGO:00310991630.040
anatomical structure morphogenesisGO:00096532980.039
activation of protein kinase activityGO:0032147470.039
lipid metabolic processGO:00066292830.039
regulation of transcription dna templatedGO:00063553740.038
hormone transportGO:00099141210.038
peptidyl amino acid modificationGO:00181931260.038
ion transmembrane transportGO:00342203650.038
brain renin angiotensin systemGO:000203530.038
respiratory system developmentGO:0060541450.037
purine ribonucleotide biosynthetic processGO:0009152810.037
activation of janus kinase activityGO:004297650.036
cellular response to peptide hormone stimulusGO:00713751200.036
regulation of cellular component organizationGO:00511283680.035
positive regulation of gene expressionGO:00106282440.035
positive regulation of phosphorus metabolic processGO:00105622620.035
Mouse
response to lipopolysaccharideGO:00324961910.035
protein localizationGO:00081041910.034
protein oligomerizationGO:00512591910.034
regulation of cell differentiationGO:00455953200.034
response to retinoic acidGO:0032526630.033
ovulation cycleGO:0042698670.033
ossificationGO:0001503700.033
cyclic nucleotide biosynthetic processGO:0009190630.032
positive regulation of cellular component organizationGO:00511302000.032
response to tumor cellGO:000234740.032
positive regulation of programmed cell deathGO:00430681570.032
positive regulation of cell deathGO:00109421840.032
organ regenerationGO:00311001010.032
regulation of catalytic activityGO:00507903040.032
regulation of nervous system developmentGO:00519602640.032
regulation of cellular amino acid metabolic processGO:000652120.031
smooth muscle cell proliferationGO:0048659770.031
divalent metal ion transportGO:00708381320.031
carbohydrate derivative biosynthetic processGO:19011371240.031
development of primary female sexual characteristicsGO:0046545560.030
blood vessel morphogenesisGO:0048514580.030
skeletal system developmentGO:0001501410.030
response to reactive oxygen speciesGO:00003021200.030
regulation of rna biosynthetic processGO:20011413810.030
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.030
positive regulation of secretionGO:00510471400.030
regulation of cytoskeleton organizationGO:0051493490.029
positive regulation of epithelial cell proliferationGO:0050679320.029
regulation of cellular ketone metabolic processGO:0010565270.029
phenol containing compound metabolic processGO:0018958300.029
peptide transportGO:0015833970.029
negative regulation of transportGO:00510511360.028
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.028
regulation of transferase activityGO:00513381230.028
regulation of calcium ion transportGO:0051924770.028
negative regulation of molecular functionGO:00440921330.028
cellular response to glucocorticoid stimulusGO:0071385680.028
actin filament based processGO:0030029860.028
mapk cascadeGO:00001651400.028
positive regulation of phosphorylationGO:00423271770.028
cellular response to interleukin 1GO:0071347370.028
positive regulation of developmental processGO:00510942830.028
Mouse
behaviorGO:00076102050.027
negative regulation of macromolecule metabolic processGO:00106052600.027
carbohydrate derivative metabolic processGO:19011353460.027
blood vessel developmentGO:0001568690.027
nucleic acid templated transcriptionGO:00976593790.027
chemosensory behaviorGO:000763520.027
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.027
cellular response to steroid hormone stimulusGO:0071383930.026
bone developmentGO:0060348250.026
cellular component assemblyGO:00226073600.026
response to radiationGO:00093141370.026
multicellular organismal signalingGO:0035637440.026
cognitionGO:0050890920.026
single organism reproductive processGO:00447022970.026
Rat
regulation of neurological system processGO:0031644430.026
regulation of multicellular organismal developmentGO:20000263760.026
cellular macromolecule localizationGO:00707271220.026
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.025
cellular response to extracellular stimulusGO:0031668730.025
negative regulation of protein metabolic processGO:00512481140.025
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.025
single organism catabolic processGO:00447122830.024
cellular response to acid chemicalGO:0071229750.024
macromolecular complex subunit organizationGO:00439333390.024
positive regulation of protein phosphorylationGO:00019341350.024
negative regulation of programmed cell deathGO:00430691830.024
regulation of growthGO:00400081050.024
Mouse
response to vitaminGO:00332731310.024
transmembrane transportGO:00550854120.024
salivary gland developmentGO:000743130.024
positive regulation of rna biosynthetic processGO:19026801970.024
positive regulation of cell proliferationGO:00082842490.024
Mouse
positive regulation of rna metabolic processGO:00512542030.024
cellular response to growth factor stimulusGO:00713631620.024
liver developmentGO:0001889900.024
divalent inorganic cation transportGO:00725111340.023
female pregnancyGO:00075651220.023
natural killer cell mediated immune response to tumor cellGO:000242310.023
embryonic appendage morphogenesisGO:003511340.023
rna biosynthetic processGO:00327743800.023
vasculature developmentGO:0001944700.023
response to growth factorGO:00708481890.022
kidney developmentGO:0001822670.022
regulation of neurogenesisGO:00507672470.022
response to chromateGO:004668730.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
response to light stimulusGO:0009416520.022
multicellular organismal reproductive processGO:00486092330.022
Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.022
positive regulation of signal transductionGO:00099671750.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
appendage morphogenesisGO:003510740.021
catabolic processGO:00090563510.021
positive regulation of catalytic activityGO:00430851840.021
negative regulation of cellular metabolic processGO:00313242810.021
inorganic cation transmembrane transportGO:00986622020.020
brain developmentGO:00074202470.020
positive regulation of protein metabolic processGO:00512471780.020
regulation of peptide transportGO:0090087870.020
positive regulation of apoptotic processGO:00430651540.020
embryonic limb morphogenesisGO:003032640.020
lung alveolus developmentGO:004828660.020
positive regulation of molecular functionGO:00440932300.020
response to ethanolGO:00454711620.020
negative regulation of cellular protein metabolic processGO:00322691060.020
protein complex assemblyGO:00064612630.020
positive regulation of locomotionGO:00400171020.019
cyclic nucleotide metabolic processGO:0009187800.019
lung developmentGO:0030324430.019
regulation of ion transportGO:00432692450.019
negative regulation of catalytic activityGO:00430861030.019
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.019
transcription from rna polymerase ii promoterGO:00063662520.019
cyclic purine nucleotide metabolic processGO:0052652620.019
regulation of cell motilityGO:20001451310.019
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.019
response to purine containing compoundGO:00140741260.019
cell growthGO:00160491040.019
regulation of anatomical structure morphogenesisGO:00226031410.019
tube developmentGO:0035295890.019
regulation of cyclic nucleotide metabolic processGO:0030799510.019
cellular chemical homeostasisGO:00550822470.019
response to fatty acidGO:0070542650.019
reactive oxygen species metabolic processGO:0072593370.019
response to interleukin 1GO:0070555550.019
positive regulation of cellular component biogenesisGO:0044089550.019
regulation of immune response to tumor cellGO:000283730.018
response to hexoseGO:00097461440.018
positive regulation of transcription dna templatedGO:00458931970.018
regulation of neuronal synaptic plasticityGO:0048168310.018
cellular protein localizationGO:00346131220.018
metal ion transportGO:00300012890.018
angiogenesisGO:0001525530.018
ribonucleotide metabolic processGO:00092592310.018
cation transportGO:00068123820.018
organic hydroxy compound metabolic processGO:19016151150.018
Mouse
purine ribonucleotide metabolic processGO:00091502270.018
amine metabolic processGO:0009308380.018
developmental growthGO:00485891000.018
Mouse
cellular amine metabolic processGO:0044106380.018
intracellular protein transportGO:0006886790.018
muscle cell proliferationGO:0033002840.018
regulation of cellular amine metabolic processGO:003323880.018
response to monosaccharideGO:00342841590.017
positive regulation of nitrogen compound metabolic processGO:00511733340.017
cell projection organizationGO:00300303020.017
anion transportGO:00068201780.017
carbohydrate metabolic processGO:00059751300.017
Mouse
actin cytoskeleton organizationGO:0030036730.017
response to oxidative stressGO:00069791860.017
respiratory tube developmentGO:0030323430.017
neuron deathGO:00709971270.017
cell migrationGO:00164771970.017
negative regulation of phosphate metabolic processGO:0045936800.017
organic hydroxy compound transportGO:0015850770.017
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.017
vasoconstrictionGO:0042310540.017
response to ionizing radiationGO:0010212590.017
positive regulation of intracellular signal transductionGO:19025331380.017
locomotionGO:00400112370.017
jak stat cascadeGO:0007259260.017
retina morphogenesis in camera type eyeGO:006004210.017
cellular lipid metabolic processGO:00442552080.017
neuron differentiationGO:00301823680.017
regulation of lyase activityGO:0051339220.017
purine containing compound biosynthetic processGO:0072522850.017
thioester metabolic processGO:0035383280.017
regulation of mapk cascadeGO:00434081160.017
cellular response to glucose stimulusGO:0071333650.017
muscle system processGO:00030121150.017
immune responseGO:00069551040.016
defense responseGO:00069521940.016
response to temperature stimulusGO:0009266940.016
olfactory behaviorGO:004204820.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
protein transportGO:00150311320.016
ribose phosphate biosynthetic processGO:0046390870.016
response to glucoseGO:00097491360.016
leukocyte cell cell adhesionGO:000715940.016
regulation of peptide secretionGO:0002791820.016
response to starvationGO:0042594590.016
positive regulation of cellular protein metabolic processGO:00322701670.016
organonitrogen compound catabolic processGO:19015651790.016
proteolysisGO:00065081750.016
response to carbohydrateGO:00097431830.016
positive regulation of protein modification processGO:00314011420.016
protein maturationGO:0051604680.016
organic acid transportGO:00158491160.016
hepaticobiliary system developmentGO:0061008900.016
organic anion transportGO:00157111320.016
positive regulation of kinase activityGO:0033674770.016
negative regulation of secretion by cellGO:1903531720.016
negative regulation of protein phosphorylationGO:0001933440.016
response to increased oxygen levelsGO:0036296450.016
regulation of sensory perception of painGO:0051930290.016
positive regulation of signalingGO:00230562700.016
muscle structure developmentGO:0061061870.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
organophosphate biosynthetic processGO:00904071430.016
Mouse
organophosphate metabolic processGO:00196373700.015
Mouse
wound healingGO:00420601220.015
regulation of intracellular signal transductionGO:19025312180.015
g protein coupled receptor signaling pathwayGO:00071862420.015
phasic smooth muscle contractionGO:001482130.015
regulation of cellular component biogenesisGO:0044087860.015
cellular amide metabolic processGO:0043603440.015
leukocyte migrationGO:0050900380.015
vesicle mediated transportGO:00161921810.015
regulation of cell projection organizationGO:00313441750.015
axis specificationGO:000979840.015
parturitionGO:0007567100.015
sulfur compound metabolic processGO:0006790700.015
protein complex biogenesisGO:00702712630.015
regulation of lipid metabolic processGO:0019216680.015
cytoskeleton organizationGO:00070101110.015
cation transmembrane transportGO:00986552630.015
regulation of amine transportGO:0051952540.014
regulation of cyclic nucleotide biosynthetic processGO:0030802450.014
cell motilityGO:00488702020.014
positive regulation of cellular amine metabolic processGO:003324030.014
response to alkaloidGO:00432791320.014
negative regulation of developmental processGO:00510931250.014
cell activationGO:0001775970.014
Mouse
calcium ion transportGO:00068161310.014
ovulation cycle processGO:0022602500.014
regulation of kinase activityGO:00435491170.014
inflammatory responseGO:00069541500.014
positive regulation of mapk cascadeGO:0043410920.014
regulation of blood vessel sizeGO:0050880890.014
peristalsisGO:003043220.014
regulation of smooth muscle cell proliferationGO:0048660750.013
purine containing compound metabolic processGO:00725212530.013
response to woundingGO:00096112540.013
protein processingGO:0016485680.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
response to ketoneGO:19016541820.013
regulation of neuron projection developmentGO:00109751610.013
organelle organizationGO:00069962660.013
negative regulation of secretionGO:0051048820.013
eye morphogenesisGO:004859240.013
purine nucleotide metabolic processGO:00061632290.013
negative regulation of phosphorus metabolic processGO:0010563800.013
negative regulation of growthGO:0045926370.013
sensory perceptionGO:00076001010.013
chemical homeostasisGO:00488782920.013
regulation of metanephros developmentGO:007221540.013
calcium ion homeostasisGO:00550741620.013
urogenital system developmentGO:0001655780.013
oligopeptide transportGO:000685740.013
carboxylic acid transportGO:00469421150.013
regulation of response to external stimulusGO:00321011060.013
sexual reproductionGO:00199531480.013
Rat
response to insulinGO:00328681330.013
cellular response to insulin stimulusGO:0032869810.013
amine transportGO:0015837570.013
neural precursor cell proliferationGO:0061351230.013
response to amino acidGO:0043200750.013
actin filament organizationGO:0007015420.013
positive regulation of growthGO:0045927550.013
Mouse
positive regulation of jak stat cascadeGO:0046427190.013
hormone secretionGO:00468791150.013
regulation of phosphatidylinositol dephosphorylationGO:006030410.013
glycerolipid metabolic processGO:0046486670.013
regulation of hormone secretionGO:00468831060.012
ribonucleotide biosynthetic processGO:0009260850.012
saliva secretionGO:004654130.012
lipid catabolic processGO:0016042460.012
regulation of proteolysisGO:0030162660.012
cellular carbohydrate metabolic processGO:0044262720.012
Mouse
regulation of homeostatic processGO:00328441010.012
tonic smooth muscle contractionGO:001482040.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
peptide metabolic processGO:0006518320.012
connective tissue developmentGO:0061448330.012
acetyl coa metabolic processGO:0006084170.012
steroid biosynthetic processGO:0006694480.012
response to testosteroneGO:0033574550.012
nucleobase containing small molecule metabolic processGO:00550863160.012
negative regulation of biosynthetic processGO:00098901680.012
positive regulation of blood circulationGO:1903524650.012
sensory perception of painGO:0019233730.012
cellular response to external stimulusGO:00714961180.012
embryonic hindlimb morphogenesisGO:003511620.012
positive regulation of peptide hormone secretionGO:0090277500.012
regulation of protein maturationGO:1903317500.012
multicellular organism growthGO:003526410.012
Mouse
developmental process involved in reproductionGO:00030061590.012
cardiovascular system developmentGO:00723581340.012
establishment of protein localizationGO:00451841410.012
reproductive structure developmentGO:00486081280.012
hormone biosynthetic processGO:0042446250.012
tissue developmentGO:00098882520.011
Rat
regulation of calcium ion dependent exocytosisGO:0017158110.011
regulation of tube sizeGO:0035150890.011
female sex differentiationGO:0046660590.011
cellular modified amino acid metabolic processGO:0006575610.011
cellular response to hexose stimulusGO:0071331650.011
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.011
somatostatin receptor signaling pathwayGO:003816940.011
metal ion homeostasisGO:00550651860.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
nucleoside phosphate biosynthetic processGO:19012931020.011
positive regulation of protein transportGO:0051222410.011
regulation of response to stressGO:00801341260.011
positive regulation of cell projection organizationGO:00313461110.011
positive regulation of transferase activityGO:0051347810.011
regulation of transmembrane transportGO:00347621220.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
reproductionGO:00000032450.011
Rat
regulation of protein kinase activityGO:00458591050.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
cytoplasmic transportGO:00164821150.011
immune system processGO:00023762040.011
Mouse
hindlimb morphogenesisGO:003513720.011
regulation of vesicle mediated transportGO:0060627810.011
mast cell chemotaxisGO:000255140.011
head developmentGO:00603222470.011
regulation of muscle system processGO:0090257790.011
regulation of cellular carbohydrate metabolic processGO:0010675390.011
Mouse
positive regulation of protein kinase activityGO:0045860730.011
response to amphetamineGO:0001975250.011
small molecule catabolic processGO:0044282590.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
rna metabolic processGO:00160704060.011
peptide hormone secretionGO:0030072840.011
excretionGO:0007588240.010
male gamete generationGO:0048232990.010
Rat
negative regulation of neuron deathGO:1901215690.010
response to hyperoxiaGO:0055093450.010
negative regulation of cell communicationGO:00106481580.010
glucose homeostasisGO:0042593750.010
purine nucleotide biosynthetic processGO:0006164830.010
norepinephrine transportGO:0015874180.010
positive regulation of neuron projection developmentGO:0010976990.010
regulation of neuron differentiationGO:00456642080.010
cellular response to cytokine stimulusGO:00713451270.010
thyroid gland developmentGO:003087810.010
response to fluorideGO:190261730.010
nucleotide metabolic processGO:00091172790.010
cellular response to ketoneGO:1901655510.010
response to toxic substanceGO:00096361330.010

Pou1f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.032
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.019
central nervous system diseaseDOID:33100.018