Rattus norvegicus

40 known processes

Hrk

harakiri, BCL2 interacting protein (contains only BH3 domain)

(Aliases: Dp5,Bid3)

Hrk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signalingGO:00072673350.561
neuron differentiationGO:00301823680.318
g protein coupled receptor signaling pathwayGO:00071862420.181
secretionGO:00469033070.179
synaptic transmissionGO:00072682350.176
detection of stimulusGO:0051606240.172
oxoacid metabolic processGO:00434362900.156
regulation of synaptic transmissionGO:00508041410.155
regulation of secretionGO:00510462240.136
secretion by cellGO:00329402480.135
positive regulation of secretionGO:00510471400.134
cell type specific apoptotic processGO:00972851340.132
regulation of mapk cascadeGO:00434081160.130
regulation of cellular localizationGO:00603412630.120
cellular homeostasisGO:00197252520.119
regulation of phosphate metabolic processGO:00192203490.115
head developmentGO:00603222470.114
cation transportGO:00068123820.114
cellular chemical homeostasisGO:00550822470.114
divalent inorganic cation transportGO:00725111340.111
regulation of membrane potentialGO:00423911100.110
positive regulation of phosphate metabolic processGO:00459372620.109
homeostatic processGO:00425923310.108
positive regulation of transportGO:00510502450.107
positive regulation of multicellular organismal processGO:00512403870.100
regulation of rna biosynthetic processGO:20011413810.098
organic acid metabolic processGO:00060822920.091
regulation of neuron apoptotic processGO:0043523830.090
cation homeostasisGO:00550801950.087
positive regulation of nitrogen compound metabolic processGO:00511733340.087
regulation of signal transductionGO:00099663180.086
protein phosphorylationGO:00064683450.083
regulation of cellular amine metabolic processGO:003323880.080
signal releaseGO:00230611450.079
regulation of apoptotic processGO:00429813350.078
transmembrane transportGO:00550854120.077
positive regulation of signal transductionGO:00099671750.077
ion transmembrane transportGO:00342203650.076
cellular ketone metabolic processGO:0042180510.076
neurotransmitter secretionGO:0007269330.075
positive regulation of molecular functionGO:00440932300.075
response to glucocorticoidGO:00513842230.072
signal transduction by phosphorylationGO:00230141440.071
regulation of cellular ketone metabolic processGO:0010565270.071
positive regulation of phosphorylationGO:00423271770.068
apoptotic processGO:00069153810.067
single organism biosynthetic processGO:00447113420.067
cellular amino acid metabolic processGO:00065201070.066
cellular cation homeostasisGO:00300031800.065
cell projection organizationGO:00300303020.064
carboxylic acid metabolic processGO:00197522890.064
regulation of nucleic acid templated transcriptionGO:19035063800.064
central nervous system developmentGO:00074173110.064
membrane organizationGO:0061024940.063
glutamate receptor signaling pathwayGO:0007215430.062
organic acid transportGO:00158491160.062
regulation of intracellular signal transductionGO:19025312180.061
cellular response to oxygen containing compoundGO:19017013860.061
calcium ion homeostasisGO:00550741620.061
positive regulation of cell communicationGO:00106472710.060
regulation of multicellular organismal developmentGO:20000263760.060
regulation of phosphorus metabolic processGO:00511743490.060
cellular protein localizationGO:00346131220.059
locomotionGO:00400112370.059
amine metabolic processGO:0009308380.059
neuron developmentGO:00486662860.059
neurological system processGO:00508772190.057
nitrogen compound transportGO:00717052290.057
positive regulation of phosphorus metabolic processGO:00105622620.057
carbohydrate derivative metabolic processGO:19011353460.056
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.056
regulation of programmed cell deathGO:00430673410.056
sexual reproductionGO:00199531480.056
transcription dna templatedGO:00063513770.056
sensory perceptionGO:00076001010.054
regulation of rna metabolic processGO:00512523910.053
regulation of secretion by cellGO:19035302080.053
intracellular signal transductionGO:00355563140.053
macromolecular complex subunit organizationGO:00439333390.052
brain developmentGO:00074202470.052
divalent metal ion transportGO:00708381320.051
positive regulation of cell deathGO:00109421840.051
reproductive processGO:00224143720.051
cation transmembrane transportGO:00986552630.050
hormone transportGO:00099141210.050
response to decreased oxygen levelsGO:00362932370.049
regulation of cell differentiationGO:00455953200.049
regulation of hormone levelsGO:00108171870.049
rna metabolic processGO:00160704060.048
ion homeostasisGO:00508012120.048
regulation of molecular functionGO:00650093980.048
regulation of cellular amino acid metabolic processGO:000652120.048
regulation of nervous system developmentGO:00519602640.048
sensory perception of painGO:0019233730.047
steroid metabolic processGO:0008202730.047
behaviorGO:00076102050.046
cellular divalent inorganic cation homeostasisGO:00725031620.046
vesicle mediated transportGO:00161921810.046
regulation of vesicle mediated transportGO:0060627810.045
regulation of neuronal synaptic plasticityGO:0048168310.045
nucleobase containing small molecule metabolic processGO:00550863160.044
defecationGO:003042110.044
nucleic acid templated transcriptionGO:00976593790.044
regulation of cellular component organizationGO:00511283680.043
neuron deathGO:00709971270.042
single organism catabolic processGO:00447122830.042
synaptic growth at neuromuscular junctionGO:005112410.041
negative regulation of metabolic processGO:00098923310.041
positive regulation of neurogenesisGO:00507691650.041
cellular component movementGO:00069282480.040
reproductionGO:00000032450.040
positive regulation of nervous system developmentGO:00519621780.040
intracellular transportGO:00469071850.040
regulation of cell developmentGO:00602842630.040
mapk cascadeGO:00001651400.040
positive regulation of developmental processGO:00510942830.040
cellular metal ion homeostasisGO:00068751720.040
organophosphate biosynthetic processGO:00904071430.039
cellular ion homeostasisGO:00068731840.039
cellular calcium ion homeostasisGO:00068741600.039
response to hypoxiaGO:00016662310.039
cellular response to lipidGO:00713962010.039
cellular component assemblyGO:00226073600.039
hormone secretionGO:00468791150.039
protein localizationGO:00081041910.038
negative regulation of cell developmentGO:0010721820.038
regulation of neuron differentiationGO:00456642080.038
nucleoside phosphate metabolic processGO:00067532830.038
single organism cellular localizationGO:19025801020.037
calcium ion transportGO:00068161310.037
positive regulation of nucleotide metabolic processGO:0045981910.037
response to ethanolGO:00454711620.036
cell morphogenesisGO:00009021420.036
positive regulation of cell differentiationGO:00455972170.036
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.036
cellular macromolecule localizationGO:00707271220.036
cellular component biogenesisGO:00440853680.036
positive regulation of secretion by cellGO:19035321280.035
response to corticosteroidGO:00319602350.035
single organism membrane organizationGO:0044802740.035
negative regulation of neurogenesisGO:0050768780.035
catabolic processGO:00090563510.034
regulation of neurogenesisGO:00507672470.034
regulation of hormone secretionGO:00468831060.034
regulation of phosphorylationGO:00423252480.034
calcium ion importGO:0070509220.034
negative regulation of nervous system developmentGO:0051961790.034
cellular amine metabolic processGO:0044106380.034
neuron apoptotic processGO:0051402880.033
establishment of protein localizationGO:00451841410.033
negative regulation of cell communicationGO:00106481580.033
prepulse inhibitionGO:006013410.033
regulation of purine nucleotide metabolic processGO:19005421150.033
regulation of neuron deathGO:19012141150.033
negative regulation of multicellular organismal processGO:00512412030.033
mechanoreceptor differentiationGO:004249020.032
inorganic ion transmembrane transportGO:00986602290.032
action potentialGO:0001508540.032
positive regulation of cellular amino acid metabolic processGO:004576410.032
metal ion transportGO:00300012890.032
response to ammonium ionGO:0060359710.032
regulation of neurotransmitter secretionGO:0046928190.032
nucleotide biosynthetic processGO:0009165980.032
forebrain developmentGO:0030900980.032
organophosphate metabolic processGO:00196373700.031
single organism behaviorGO:00447081300.031
amide transportGO:00428861050.031
rna biosynthetic processGO:00327743800.031
regulation of neuron projection developmentGO:00109751610.031
ribonucleotide biosynthetic processGO:0009260850.030
regulation of system processGO:00440572080.030
alcohol metabolic processGO:0006066770.030
neuron projection developmentGO:00311752730.030
regulation of protein modification processGO:00313991940.030
positive regulation of cell developmentGO:00107201760.030
neurotransmitter transportGO:0006836420.030
positive regulation of neurotransmitter secretionGO:000195690.030
purine containing compound metabolic processGO:00725212530.030
divalent inorganic cation homeostasisGO:00725071650.030
organic substance catabolic processGO:19015753160.030
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.029
acid secretionGO:0046717480.029
positive regulation of mapk cascadeGO:0043410920.029
single organism intracellular transportGO:19025821660.029
single organism reproductive processGO:00447022970.029
metal ion homeostasisGO:00550651860.029
positive regulation of signalingGO:00230562700.028
regulation of transcription dna templatedGO:00063553740.028
positive regulation of catalytic activityGO:00430851840.028
protein localization to membraneGO:0072657360.028
chemical homeostasisGO:00488782920.028
positive regulation of cell proliferationGO:00082842490.028
regulation of protein phosphorylationGO:00019321830.028
cell migrationGO:00164771970.028
organic anion transportGO:00157111320.027
organonitrogen compound biosynthetic processGO:19015661670.027
cellular response to endogenous stimulusGO:00714953770.027
cell part morphogenesisGO:00329901230.027
regulation of synaptic plasticityGO:0048167700.027
response to oxygen levelsGO:00704822650.027
multi organism reproductive processGO:00447032620.026
response to alkaloidGO:00432791320.026
positive regulation of cellular biosynthetic processGO:00313282950.026
organic hydroxy compound metabolic processGO:19016151150.026
positive regulation of protein kinase activityGO:0045860730.026
negative regulation of nucleobase containing compound metabolic processGO:00459341530.026
positive regulation of purine nucleotide metabolic processGO:1900544910.026
gamete generationGO:00072761240.026
astrocyte developmentGO:001400240.025
regulation of calcium ion transportGO:0051924770.025
response to extracellular stimulusGO:00099913800.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
cytosolic calcium ion homeostasisGO:00514801400.025
cognitionGO:0050890920.024
purine ribonucleotide metabolic processGO:00091502270.024
response to carbohydrateGO:00097431830.024
positive regulation of intracellular signal transductionGO:19025331380.024
ribonucleotide metabolic processGO:00092592310.024
multicellular organismal reproductive processGO:00486092330.024
lipid metabolic processGO:00066292830.024
ribose phosphate biosynthetic processGO:0046390870.024
organelle organizationGO:00069962660.024
purine nucleotide metabolic processGO:00061632290.024
regulation of neurotransmitter levelsGO:0001505420.023
retinal ganglion cell axon guidanceGO:003129010.023
organic cyclic compound catabolic processGO:19013611750.023
glutamate secretionGO:0014047190.023
adult locomotory behaviorGO:000834440.023
regulation of ion transmembrane transportGO:00347651210.022
cellular response to organonitrogen compoundGO:00714171970.022
small molecule biosynthetic processGO:00442831240.022
response to ketoneGO:19016541820.022
anatomical structure morphogenesisGO:00096532980.022
negative regulation of cellular metabolic processGO:00313242810.022
organonitrogen compound catabolic processGO:19015651790.022
regulation of cellular protein metabolic processGO:00322682670.022
positive regulation of neuron differentiationGO:00456661260.021
nucleoside phosphate biosynthetic processGO:19012931020.021
programmed cell deathGO:00125013920.021
learning or memoryGO:0007611900.021
nucleotide metabolic processGO:00091172790.021
positive regulation of response to stimulusGO:00485842850.021
negative regulation of programmed cell deathGO:00430691830.021
ribonucleoside catabolic processGO:00424541260.021
positive regulation of synaptic transmissionGO:0050806620.021
positive regulation of biosynthetic processGO:00098913190.020
negative regulation of cellular component organizationGO:0051129830.020
positive regulation of cellular amine metabolic processGO:003324030.020
ribose phosphate metabolic processGO:00196932350.020
response to inorganic substanceGO:00100353770.020
heterocycle catabolic processGO:00467001670.020
neuronal action potentialGO:0019228350.020
regulation of defecationGO:200029210.020
cellular response to organic cyclic compoundGO:00714072020.020
positive regulation of programmed cell deathGO:00430681570.020
organelle localizationGO:0051640550.020
amine transportGO:0015837570.020
second messenger mediated signalingGO:0019932510.020
purine nucleotide biosynthetic processGO:0006164830.020
neuron neuron synaptic transmissionGO:0007270600.020
negative regulation of signalingGO:00230571570.020
peptide transportGO:0015833970.020
positive regulation of gene expressionGO:00106282440.019
synaptic transmission glutamatergicGO:0035249330.019
peptidyl amino acid modificationGO:00181931260.019
locomotory exploration behaviorGO:003564110.019
regulation of excitatory postsynaptic membrane potentialGO:0060079180.019
axon guidanceGO:0007411240.019
carbohydrate derivative biosynthetic processGO:19011371240.019
purine nucleoside triphosphate metabolic processGO:00091441410.018
regulation of transferase activityGO:00513381230.018
purine nucleoside metabolic processGO:00422781690.018
monoamine transportGO:0015844430.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
carbohydrate homeostasisGO:0033500750.018
regulation of nucleotide metabolic processGO:00061401170.018
hair cell differentiationGO:003531520.018
positive regulation of protein modification processGO:00314011420.018
regulation of cell proliferationGO:00421273590.017
carboxylic acid transportGO:00469421150.017
multicellular organism reproductionGO:00325042330.017
regulation of amino acid transportGO:0051955250.017
response to cytokineGO:00340972150.017
protein complex biogenesisGO:00702712630.017
negative regulation of transportGO:00510511360.017
positive regulation of protein metabolic processGO:00512471780.017
cellular component morphogenesisGO:00329891550.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
response to nutrient levelsGO:00316673700.017
positive regulation of ion transportGO:0043270940.017
regulation of axonogenesisGO:0050770370.017
cyclic nucleotide metabolic processGO:0009187800.017
cell projection morphogenesisGO:00488581230.017
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.017
regulation of catalytic activityGO:00507903040.017
negative regulation of gene expressionGO:00106291990.016
exploration behaviorGO:003564010.016
regulation of anatomical structure morphogenesisGO:00226031410.016
macromolecular complex assemblyGO:00650032730.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
exocytosisGO:0006887600.016
detection of abiotic stimulusGO:0009582130.016
protein transportGO:00150311320.016
cellular response to alcoholGO:0097306870.016
negative regulation of macromolecule metabolic processGO:00106052600.016
muscle system processGO:00030121150.016
synaptic transmission gabaergicGO:0051932220.015
protein complex assemblyGO:00064612630.015
transmission of nerve impulseGO:0019226420.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
negative regulation of response to stimulusGO:00485851550.015
ionotropic glutamate receptor signaling pathwayGO:0035235340.015
multicellular organismal signalingGO:0035637440.015
regulation of ion transportGO:00432692450.015
regulation of postsynaptic membrane potentialGO:0060078250.015
response to monosaccharideGO:00342841590.015
negative regulation of cell differentiationGO:0045596990.015
carbohydrate derivative catabolic processGO:19011361470.015
axon ensheathmentGO:0008366400.015
axon developmentGO:0061564960.015
nucleotide catabolic processGO:00091661390.015
regulation of neurotransmitter transportGO:0051588210.015
gastric inhibitory peptide signaling pathwayGO:003819210.015
positive regulation of nucleotide biosynthetic processGO:0030810360.015
nucleoside metabolic processGO:00091161790.015
response to glucoseGO:00097491360.015
nucleoside triphosphate metabolic processGO:00091411440.015
male gamete generationGO:0048232990.015
memoryGO:0007613540.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
ras protein signal transductionGO:0007265290.015
single organism carbohydrate metabolic processGO:00447231180.015
amino acid transportGO:0006865700.015
peptide secretionGO:0002790860.015
negative regulation of apoptotic processGO:00430661810.014
positive regulation of transferase activityGO:0051347810.014
negative regulation of rna biosynthetic processGO:19026791180.014
regulation of peptide secretionGO:0002791820.014
peptidyl tyrosine phosphorylationGO:0018108720.014
regulation of developmental growthGO:0048638450.014
telencephalon developmentGO:0021537620.014
response to hexoseGO:00097461440.014
neuromuscular processGO:005090520.014
camp biosynthetic processGO:0006171470.014
glycosyl compound metabolic processGO:19016571820.014
motor neuron axon guidanceGO:000804510.014
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.014
positive regulation of protein serine threonine kinase activityGO:0071902520.014
cyclic nucleotide biosynthetic processGO:0009190630.014
response to calcium ionGO:0051592590.014
intracellular protein transportGO:0006886790.014
response to cocaineGO:0042220390.014
regulation of kinase activityGO:00435491170.014
cellular response to growth factor stimulusGO:00713631620.014
response to growth factorGO:00708481890.014
regulation of nucleotide biosynthetic processGO:0030808470.014
purine nucleoside catabolic processGO:00061521240.013
positive regulation of cellular component biogenesisGO:0044089550.013
positive regulation of cellular protein metabolic processGO:00322701670.013
purine containing compound biosynthetic processGO:0072522850.013
positive regulation of protein phosphorylationGO:00019341350.013
myelinationGO:0042552390.013
agingGO:00075682410.013
respiratory gaseous exchangeGO:000758540.013
gonad developmentGO:00084061040.013
sex differentiationGO:00075481130.013
inner ear receptor cell differentiationGO:006011320.013
regulation of cell morphogenesis involved in differentiationGO:0010769720.013
urogenital system developmentGO:0001655780.013
neuron projection morphogenesisGO:00488121220.013
steroid biosynthetic processGO:0006694480.013
inorganic cation transmembrane transportGO:00986622020.013
negative regulation of neuron apoptotic processGO:0043524450.013
cellular response to steroid hormone stimulusGO:0071383930.013
regulation of amine transportGO:0051952540.013
negative regulation of macromolecule biosynthetic processGO:00105581480.012
adenosine receptor signaling pathwayGO:000197370.012
regulation of respiratory gaseous exchange by neurological system processGO:000208710.012
potassium ion transportGO:0006813970.012
purine nucleotide catabolic processGO:00061951360.012
anion transportGO:00068201780.012
detection of chemical stimulusGO:0009593100.012
maintenance of locationGO:0051235170.012
positive regulation of neuron apoptotic processGO:0043525330.012
positive regulation of cyclase activityGO:0031281150.012
cellular response to hormone stimulusGO:00328702470.012
cyclic purine nucleotide metabolic processGO:0052652620.012
tissue developmentGO:00098882520.012
response to fatty acidGO:0070542650.012
response to woundingGO:00096112540.012
response to activityGO:0014823730.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
negative regulation of circadian sleep wake cycle non rem sleepGO:004232320.012
aromatic compound catabolic processGO:00194391680.012
positive regulation of serotonin secretionGO:001406410.012
establishment of synaptic vesicle localizationGO:0097480230.012
response to metal ionGO:00100382530.012
regulation of cell morphogenesisGO:0022604770.012
cellular response to glucose stimulusGO:0071333650.012
cell motilityGO:00488702020.011
peptide hormone secretionGO:0030072840.011
glial cell differentiationGO:0010001650.011
gliogenesisGO:0042063930.011
synaptic vesicle localizationGO:0097479240.011
response to oxidative stressGO:00069791860.011
cerebellar purkinje cell layer developmentGO:002168020.011
cellular response to stressGO:00335542690.011
positive regulation of neuron deathGO:1901216430.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
cellular catabolic processGO:00442482950.011
purine ribonucleotide biosynthetic processGO:0009152810.011
negative regulation of cellular biosynthetic processGO:00313271610.011
lipid biosynthetic processGO:00086101280.011
ribonucleoside metabolic processGO:00091191740.011
regulation of cell projection organizationGO:00313441750.011
chromosome segregationGO:000705920.011
oxidation reduction processGO:00551143040.011
positive regulation of purine nucleotide biosynthetic processGO:1900373360.011
single organism organelle organizationGO:19025891800.011
protein complex subunit organizationGO:00718223020.011
anterior posterior pattern specificationGO:000995210.011
positive regulation of apoptotic processGO:00430651540.011
regulation of camp biosynthetic processGO:0030817380.011
axis specificationGO:000979840.011
negative regulation of cell deathGO:00605482290.011
spermatogenesisGO:0007283990.011
endomembrane system organizationGO:0010256480.011
limbic system developmentGO:0021761380.011
positive regulation of cellular component organizationGO:00511302000.011
purine ribonucleoside metabolic processGO:00461281680.011
protein oligomerizationGO:00512591910.011
positive regulation of rna metabolic processGO:00512542030.011
regulation of catabolic processGO:00098941130.011
nuclear transportGO:0051169490.011
regulation of protein metabolic processGO:00512462890.011
regulation of purine nucleotide catabolic processGO:0033121650.011
protein targetingGO:0006605610.011
response to electrical stimulusGO:0051602560.011
taxisGO:0042330670.011
inflammatory responseGO:00069541500.010
skeletal system developmentGO:0001501410.010
cellular response to carbohydrate stimulusGO:0071322720.010
astrocyte activationGO:004814340.010
cellular response to monosaccharide stimulusGO:0071326670.010
embryonic pattern specificationGO:000988010.010
cellular nitrogen compound catabolic processGO:00442701630.010
protein homooligomerizationGO:0051260910.010
actin cytoskeleton organizationGO:0030036730.010
developmental process involved in reproductionGO:00030061590.010
hormone mediated signaling pathwayGO:0009755230.010
insulin secretionGO:0030073690.010

Hrk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.012