Rattus norvegicus

12 known processes

Sptan1

spectrin, alpha, non-erythrocytic 1

(Aliases: A2a,IPF,Spna2)

Sptan1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.616
Zebrafish
cellular component movementGO:00069282480.329
cell projection organizationGO:00300303020.277
cellular component biogenesisGO:00440853680.255
regulation of cell developmentGO:00602842630.243
cellular component morphogenesisGO:00329891550.222
single organism behaviorGO:00447081300.220
regulation of neurogenesisGO:00507672470.180
negative regulation of nervous system developmentGO:0051961790.180
cellular cation homeostasisGO:00300031800.163
learning or memoryGO:0007611900.154
regulation of purine nucleotide catabolic processGO:0033121650.152
cell projection morphogenesisGO:00488581230.152
response to metal ionGO:00100382530.148
cellular calcium ion homeostasisGO:00068741600.146
learningGO:0007612330.145
adult locomotory behaviorGO:000834440.144
lipid metabolic processGO:00066292830.140
neuron projection developmentGO:00311752730.134
metal ion homeostasisGO:00550651860.129
neuron developmentGO:00486662860.120
Zebrafish
protein transportGO:00150311320.120
vesicle mediated transportGO:00161921810.118
organelle organizationGO:00069962660.113
central nervous system developmentGO:00074173110.101
cell type specific apoptotic processGO:00972851340.100
purine nucleotide catabolic processGO:00061951360.099
response to nutrient levelsGO:00316673700.099
protein complex biogenesisGO:00702712630.097
negative regulation of neuron differentiationGO:0045665620.094
cellular homeostasisGO:00197252520.093
cellular metal ion homeostasisGO:00068751720.092
synaptic transmissionGO:00072682350.090
axonogenesisGO:0007409710.090
regulation of neuron differentiationGO:00456642080.089
regulation of multicellular organismal developmentGO:20000263760.089
positive regulation of neuron projection developmentGO:0010976990.087
ribonucleotide catabolic processGO:00092611360.087
regulation of cell differentiationGO:00455953200.084
positive regulation of developmental processGO:00510942830.083
head developmentGO:00603222470.082
response to organophosphorusGO:00466831020.082
neurological system processGO:00508772190.081
carbohydrate derivative catabolic processGO:19011361470.081
regulation of nervous system developmentGO:00519602640.079
ionotropic glutamate receptor signaling pathwayGO:0035235340.079
positive regulation of multicellular organismal processGO:00512403870.078
visual learningGO:000854280.078
cell morphogenesis involved in neuron differentiationGO:00486671060.074
regulation of molecular functionGO:00650093980.074
organophosphate metabolic processGO:00196373700.073
regulation of anatomical structure sizeGO:00900661350.073
single organism cellular localizationGO:19025801020.071
positive regulation of cell developmentGO:00107201760.070
divalent inorganic cation homeostasisGO:00725071650.069
cell morphogenesisGO:00009021420.069
intracellular transportGO:00469071850.068
transmembrane transportGO:00550854120.068
purine containing compound metabolic processGO:00725212530.068
cell morphogenesis involved in differentiationGO:00009041190.068
regulation of cellular component organizationGO:00511283680.067
regulation of cell projection organizationGO:00313441750.066
dendrite morphogenesisGO:0048813430.065
axon cargo transportGO:000808810.065
glutamate receptor signaling pathwayGO:0007215430.065
adult behaviorGO:0030534160.064
neuron projection morphogenesisGO:00488121220.064
reproductive processGO:00224143720.064
catabolic processGO:00090563510.064
cation homeostasisGO:00550801950.062
response to nutrientGO:00075842480.061
synapse organizationGO:0050808460.061
cellular divalent inorganic cation homeostasisGO:00725031620.061
intracellular protein transportGO:0006886790.061
macromolecular complex subunit organizationGO:00439333390.060
axon choice point recognitionGO:001619820.057
cellular response to organonitrogen compoundGO:00714171970.057
regulation of phosphate metabolic processGO:00192203490.056
cognitionGO:0050890920.056
single organism organelle organizationGO:19025891800.055
positive regulation of cell differentiationGO:00455972170.054
macromolecular complex assemblyGO:00650032730.054
actin cytoskeleton organizationGO:0030036730.053
inorganic cation transmembrane transportGO:00986622020.053
nucleoside phosphate catabolic processGO:19012921400.053
carbohydrate derivative metabolic processGO:19011353460.052
positive regulation of hydrolase activityGO:0051345860.052
regulation of neuron projection developmentGO:00109751610.051
associative learningGO:0008306190.051
protein phosphorylationGO:00064683450.051
single organism catabolic processGO:00447122830.051
g protein coupled receptor signaling pathwayGO:00071862420.051
inorganic ion transmembrane transportGO:00986602290.050
positive regulation of neurogenesisGO:00507691650.050
axon developmentGO:0061564960.050
regulation of ion transmembrane transporter activityGO:0032412480.049
organic hydroxy compound metabolic processGO:19016151150.048
regulation of cellular component movementGO:00512701500.048
cell adhesionGO:00071551100.047
epithelium developmentGO:0060429960.047
ion transmembrane transportGO:00342203650.044
cellular chemical homeostasisGO:00550822470.044
cellular component assemblyGO:00226073600.043
calcium ion homeostasisGO:00550741620.043
cellular ion homeostasisGO:00068731840.043
response to purine containing compoundGO:00140741260.042
multi multicellular organism processGO:00447061380.042
chemical homeostasisGO:00488782920.041
anatomical structure morphogenesisGO:00096532980.041
synaptic vesicle transportGO:0048489230.040
ion homeostasisGO:00508012120.040
synaptic growth at neuromuscular junctionGO:005112410.040
protein complex subunit organizationGO:00718223020.040
ras protein signal transductionGO:0007265290.040
actin filament based processGO:0030029860.040
alcohol metabolic processGO:0006066770.040
regulation of cell migrationGO:00303341280.039
purine ribonucleotide metabolic processGO:00091502270.038
cell motilityGO:00488702020.037
synaptic vesicle endocytosisGO:004848840.037
reproductionGO:00000032450.037
regulation of blood circulationGO:19035221100.036
circulatory system processGO:00030131830.036
cellular response to endogenous stimulusGO:00714953770.036
negative regulation of multicellular organismal processGO:00512412030.036
homeostatic processGO:00425923310.036
nucleotide catabolic processGO:00091661390.036
negative regulation of molecular functionGO:00440921330.035
negative regulation of neurogenesisGO:0050768780.035
guanosine containing compound metabolic processGO:1901068740.035
multi organism reproductive processGO:00447032620.034
cytosolic calcium ion homeostasisGO:00514801400.034
response to acid chemicalGO:00011012220.034
regulation of axonogenesisGO:0050770370.034
cellular nitrogen compound catabolic processGO:00442701630.034
cytoplasmic transportGO:00164821150.034
female pregnancyGO:00075651220.033
positive regulation of gene expressionGO:00106282440.033
purine ribonucleoside catabolic processGO:00461301240.033
anatomical structure formation involved in morphogenesisGO:0048646830.033
neuron recognitionGO:000803890.032
steroid metabolic processGO:0008202730.032
nucleoside triphosphate catabolic processGO:00091431230.032
negative regulation of cell developmentGO:0010721820.032
circulatory system developmentGO:00723591340.032
small gtpase mediated signal transductionGO:0007264360.032
coagulationGO:0050817280.032
regulation of protein kinase activityGO:00458591050.031
spindle organizationGO:000705120.031
multicellular organism growthGO:003526410.031
neuromuscular processGO:005090520.031
purine nucleoside triphosphate metabolic processGO:00091441410.031
positive regulation of neuron differentiationGO:00456661260.030
protein complex assemblyGO:00064612630.030
regulation of signal transductionGO:00099663180.030
positive regulation of cellular component organizationGO:00511302000.030
synaptic vesicle primingGO:001608240.029
regulation of cellular amino acid metabolic processGO:000652120.029
nucleobase containing small molecule metabolic processGO:00550863160.029
muscle structure developmentGO:0061061870.029
regulation of transporter activityGO:0032409500.029
glycosyl compound catabolic processGO:19016581260.029
response to inorganic substanceGO:00100353770.029
regulation of receptor activityGO:0010469290.029
regulation of protein phosphorylationGO:00019321830.028
brain developmentGO:00074202470.028
wound healingGO:00420601220.028
negative regulation of developmental processGO:00510931250.027
blood circulationGO:00080151830.027
response to transition metal nanoparticleGO:19902671220.027
protein targetingGO:0006605610.027
intracellular signal transductionGO:00355563140.027
membrane organizationGO:0061024940.027
Zebrafish
visual behaviorGO:000763290.027
sequestering of calcium ionGO:005120880.027
regulation of intracellular signal transductionGO:19025312180.026
response to calcium ionGO:0051592590.026
response to alkaloidGO:00432791320.026
establishment of protein localizationGO:00451841410.026
cellular response to oxygen containing compoundGO:19017013860.026
response to oxidative stressGO:00069791860.026
nucleotide metabolic processGO:00091172790.026
glycosyl compound metabolic processGO:19016571820.026
actin cytoskeleton reorganizationGO:003153280.026
regulation of nucleotide catabolic processGO:0030811650.025
cellular response to lipidGO:00713962010.025
carboxylic acid metabolic processGO:00197522890.025
regulation of cellular ketone metabolic processGO:0010565270.025
cardiac muscle cell contractionGO:0086003100.025
sexual reproductionGO:00199531480.025
extracellular structure organizationGO:0043062130.025
response to radiationGO:00093141370.024
response to extracellular stimulusGO:00099913800.024
nucleobase containing compound catabolic processGO:00346551520.024
divalent inorganic cation transportGO:00725111340.024
secretionGO:00469033070.024
positive regulation of cell cycle g2 m phase transitionGO:190275110.024
cellular amino acid metabolic processGO:00065201070.024
ribonucleotide metabolic processGO:00092592310.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
endocytosisGO:0006897840.024
protein heterooligomerizationGO:0051291890.024
nucleoside metabolic processGO:00091161790.024
regulation of sodium ion transmembrane transporter activityGO:200064940.023
glial cell differentiationGO:0010001650.023
positive regulation of rho gtpase activityGO:0032321130.023
nucleoside phosphate metabolic processGO:00067532830.023
programmed cell deathGO:00125013920.023
neuron deathGO:00709971270.023
neuron neuron synaptic transmissionGO:0007270600.023
regulation of heart contractionGO:0008016480.023
regulation of transferase activityGO:00513381230.023
single organismal cell cell adhesionGO:0016337420.023
cellular macromolecule localizationGO:00707271220.023
forebrain developmentGO:0030900980.023
mitotic spindle organizationGO:000705220.022
positive regulation of cell projection organizationGO:00313461110.022
cell cycleGO:00070491010.022
positive regulation of rna biosynthetic processGO:19026801970.022
positive regulation of catalytic activityGO:00430851840.022
mitochondrion localizationGO:005164660.022
regulation of anatomical structure morphogenesisGO:00226031410.021
positive regulation of nucleoside metabolic processGO:0045979550.021
regulation of catalytic activityGO:00507903040.021
organophosphate catabolic processGO:00464341480.021
cell cell signalingGO:00072673350.021
positive regulation of cell communicationGO:00106472710.021
organic cyclic compound catabolic processGO:19013611750.021
membrane hyperpolarizationGO:0060081110.021
synaptic transmission gabaergicGO:0051932220.020
regulation of phosphorus metabolic processGO:00511743490.020
double strand break repairGO:000630210.020
calcium ion transportGO:00068161310.020
calcium ion transmembrane transportGO:0070588700.020
regulation of body fluid levelsGO:0050878900.020
metal ion transportGO:00300012890.020
behaviorGO:00076102050.020
protein oligomerizationGO:00512591910.020
organophosphate biosynthetic processGO:00904071430.020
single organism cell adhesionGO:0098602460.020
regulation of purine nucleotide metabolic processGO:19005421150.020
regulation of system processGO:00440572080.020
regulation of cellular amine metabolic processGO:003323880.020
centrosome cycleGO:000709810.020
organic acid metabolic processGO:00060822920.020
heart processGO:0003015570.019
ribonucleoside metabolic processGO:00091191740.019
positive regulation of nervous system developmentGO:00519621780.019
response to decreased oxygen levelsGO:00362932370.019
hemostasisGO:0007599260.019
purine containing compound catabolic processGO:00725231380.019
multicellular organismal signalingGO:0035637440.019
norepinephrine secretionGO:0048243160.019
single organism intracellular transportGO:19025821660.019
feeding behaviorGO:0007631530.019
regulation of rna biosynthetic processGO:20011413810.019
cellular response to oxidative stressGO:0034599760.019
cellular catabolic processGO:00442482950.019
response to oxygen levelsGO:00704822650.019
retrograde axon cargo transportGO:000809010.019
regulation of kinase activityGO:00435491170.019
single organism membrane organizationGO:0044802740.018
Zebrafish
response to campGO:0051591910.018
secretion by cellGO:00329402480.018
regulation of postsynaptic membrane potentialGO:0060078250.018
protein localization to membraneGO:0072657360.018
ribonucleoside triphosphate catabolic processGO:00092031220.018
negative regulation of cellular component organizationGO:0051129830.018
purine nucleotide metabolic processGO:00061632290.018
synaptic vesicle localizationGO:0097479240.018
cellular lipid metabolic processGO:00442552080.018
amine metabolic processGO:0009308380.018
single organism biosynthetic processGO:00447113420.018
cellular component maintenanceGO:004395440.018
cardiac muscle contractionGO:0060048270.018
cellular response to abiotic stimulusGO:0071214850.018
regulation of gtpase activityGO:0043087570.018
cellular macromolecular complex assemblyGO:0034622580.017
organonitrogen compound catabolic processGO:19015651790.017
positive regulation of nucleotide catabolic processGO:0030813530.017
ribonucleoside catabolic processGO:00424541260.017
regulation of cell cycle g2 m phase transitionGO:190274940.017
cellular protein complex assemblyGO:0043623440.017
multicellular organismal reproductive processGO:00486092330.017
axon midline choice point recognitionGO:001619920.017
purine nucleoside triphosphate catabolic processGO:00091461220.017
protein homooligomerizationGO:0051260910.017
cellular response to organic cyclic compoundGO:00714072020.017
response to corticosteroidGO:00319602350.017
cellular amine metabolic processGO:0044106380.017
regulation of nucleoside metabolic processGO:0009118660.016
monovalent inorganic cation transportGO:00156721720.016
dendrite developmentGO:0016358720.016
positive regulation of molecular functionGO:00440932300.016
regulation of ion transportGO:00432692450.016
protein localizationGO:00081041910.016
negative regulation of cell communicationGO:00106481580.016
platelet aggregationGO:007052740.016
taxisGO:0042330670.016
establishment of protein localization to membraneGO:0090150160.016
regulation of protein maturationGO:1903317500.016
aromatic compound catabolic processGO:00194391680.016
response to woundingGO:00096112540.016
apoptotic processGO:00069153810.016
neuron apoptotic processGO:0051402880.016
regulation of g2 m transition of mitotic cell cycleGO:001038940.016
organic substance catabolic processGO:19015753160.016
regulation of actin filament based processGO:0032970420.015
negative regulation of transportGO:00510511360.015
vasculature developmentGO:0001944700.015
regulation of metal ion transportGO:00109591180.015
regulation of developmental growthGO:0048638450.015
cardiac chamber developmentGO:000320510.015
gtp metabolic processGO:0046039720.015
developmental growthGO:00485891000.015
cell fate determinationGO:000170920.015
actin mediated cell contractionGO:0070252120.015
regulation of programmed cell deathGO:00430673410.015
positive regulation of biosynthetic processGO:00098913190.015
regulation of neurotransmitter levelsGO:0001505420.015
rna localizationGO:000640340.015
heterocycle catabolic processGO:00467001670.015
cardiovascular system developmentGO:00723581340.015
multicellular organism reproductionGO:00325042330.014
regulation of smooth muscle cell proliferationGO:0048660750.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.014
response to cadmium ionGO:0046686350.014
purine nucleoside catabolic processGO:00061521240.014
microtubule organizing center organizationGO:003102310.014
regulation of calcium ion transportGO:0051924770.014
neurotransmitter transportGO:0006836420.014
positive regulation of protein phosphorylationGO:00019341350.014
divalent metal ion transportGO:00708381320.014
macromolecule localizationGO:00330362520.014
regulation of tube sizeGO:0035150890.014
response to ammonium ionGO:0060359710.014
response to ketoneGO:19016541820.014
cellular ketone metabolic processGO:0042180510.014
cholesterol metabolic processGO:0008203170.014
regulation of protein transportGO:0051223680.014
peptidyl amino acid modificationGO:00181931260.014
sequestering of metal ionGO:005123890.014
response to amino acidGO:0043200750.014
positive regulation of gtp catabolic processGO:0033126480.013
positive regulation of phosphate metabolic processGO:00459372620.013
muscle tissue developmentGO:0060537580.013
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.013
blood coagulationGO:0007596260.013
insulin like growth factor receptor signaling pathwayGO:004800930.013
positive regulation of phosphorylationGO:00423271770.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
cellular response to cgmpGO:007132120.013
negative regulation of proteolysisGO:0045861410.013
leukocyte activationGO:0045321760.013
peptidyl tyrosine modificationGO:0018212720.013
purine ribonucleotide catabolic processGO:00091541360.013
muscle system processGO:00030121150.013
response to hypoxiaGO:00016662310.013
positive regulation of cellular biosynthetic processGO:00313282950.013
negative regulation of cell proliferationGO:00082851190.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
inflammatory responseGO:00069541500.013
chemotaxisGO:0006935660.013
cellular response to nitrogen compoundGO:19016992100.012
cell growthGO:00160491040.012
response to glucocorticoidGO:00513842230.012
muscle cell differentiationGO:0042692520.012
regulation of protein modification processGO:00313991940.012
transcription from rna polymerase ii promoterGO:00063662520.012
organelle localizationGO:0051640550.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
liver developmentGO:0001889900.012
mrna 3 end processingGO:003112410.012
regulation of nucleotide metabolic processGO:00061401170.012
nucleoside catabolic processGO:00091641260.012
regulation of gtp catabolic processGO:0033124580.012
regulation of ion transmembrane transportGO:00347651210.012
regulation of angiogenesisGO:0045765390.012
cell part morphogenesisGO:00329901230.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
negative regulation of catalytic activityGO:00430861030.011
striated muscle cell differentiationGO:0051146390.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of striated muscle contractionGO:0006942210.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
positive regulation of cellular protein metabolic processGO:00322701670.011
locomotionGO:00400112370.011
male gamete generationGO:0048232990.011
cyclic purine nucleotide metabolic processGO:0052652620.011
positive regulation of nitrogen compound metabolic processGO:00511733340.011
positive regulation of apoptotic processGO:00430651540.011
tissue developmentGO:00098882520.011
mitotic cell cycle processGO:1903047350.011
neurotransmitter gated ion channel clusteringGO:007257830.011
mitochondrion organizationGO:0007005350.011
regulation of calcium ion transmembrane transporter activityGO:1901019170.011
epithelial cell differentiationGO:0030855710.011
striated muscle tissue developmentGO:0014706580.011
cellular response to acid chemicalGO:0071229750.011
protein dna complex disassemblyGO:003298610.011
response to cgmpGO:007030530.011
regulation of vasoconstrictionGO:0019229440.011
regulation of camp metabolic processGO:0030814430.011
peptidyl tyrosine phosphorylationGO:0018108720.011
regulation of cellular component biogenesisGO:0044087860.011
maintenance of locationGO:0051235170.011
regulation of membrane potentialGO:00423911100.011
organic hydroxy compound transportGO:0015850770.011
cell activationGO:0001775970.010
positive regulation of purine nucleotide catabolic processGO:0033123530.010
sensory organ developmentGO:0007423740.010
negative regulation of neuron projection developmentGO:0010977460.010
cation transportGO:00068123820.010
synapse assemblyGO:0007416290.010
nucleoside monophosphate metabolic processGO:0009123930.010
lens fiber cell differentiationGO:007030630.010
regulation of cardiac muscle cell action potentialGO:009890130.010
nucleic acid transportGO:005065730.010
sterol metabolic processGO:0016125180.010
regulation of hydrolase activityGO:00513361430.010
cell cycle processGO:0022402570.010
positive regulation of nucleobase containing compound metabolic processGO:00459353190.010
regulation of synaptic plasticityGO:0048167700.010
protein prenylationGO:001834240.010
regulation of protein processingGO:0070613500.010
regulation of transmembrane transportGO:00347621220.010

Sptan1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.274
Human
disease of anatomical entityDOID:700.274
Human
central nervous system diseaseDOID:33100.148
Human
disease of metabolismDOID:001466700.038
brain diseaseDOID:93600.014
Human
ohtahara syndromeDOID:005070900.014
Human
electroclinical syndromeDOID:005070100.014
Human
neonatal period electroclinical syndromeDOID:005070200.014
Human
epilepsy syndromeDOID:182600.014
Human
acquired metabolic diseaseDOID:006015800.011