Rattus norvegicus

29 known processes

Plb1

phospholipase B1

(Aliases: Phlpb)

Plb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle system processGO:00030121150.645
carboxylic acid metabolic processGO:00197522890.639
muscle contractionGO:0006936880.386
positive regulation of multicellular organismal processGO:00512403870.354
cellular response to lipidGO:00713962010.346
negative regulation of cellular metabolic processGO:00313242810.337
negative regulation of gene expressionGO:00106291990.331
cellular response to organonitrogen compoundGO:00714171970.322
response to peptide hormoneGO:00434342780.282
negative regulation of metabolic processGO:00098923310.235
rna biosynthetic processGO:00327743800.231
cellular response to hormone stimulusGO:00328702470.229
cation transmembrane transportGO:00986552630.216
cellular response to endogenous stimulusGO:00714953770.216
positive regulation of macromolecule biosynthetic processGO:00105572470.204
response to other organismGO:00517072200.198
response to estrogenGO:00436272320.195
cellular lipid metabolic processGO:00442552080.193
oxoacid metabolic processGO:00434362900.191
cardiovascular system developmentGO:00723581340.190
regulation of transcription dna templatedGO:00063553740.189
response to peptideGO:19016522920.184
organic acid metabolic processGO:00060822920.183
transcription from rna polymerase ii promoterGO:00063662520.183
regulation of rna metabolic processGO:00512523910.179
inorganic cation transmembrane transportGO:00986622020.167
rna metabolic processGO:00160704060.167
negative regulation of nitrogen compound metabolic processGO:00511721610.163
positive regulation of biosynthetic processGO:00098913190.161
regulation of nucleic acid templated transcriptionGO:19035063800.160
positive regulation of developmental processGO:00510942830.159
negative regulation of cellular biosynthetic processGO:00313271610.151
negative regulation of nucleobase containing compound metabolic processGO:00459341530.150
regulation of rna biosynthetic processGO:20011413810.148
cellular response to oxygen containing compoundGO:19017013860.148
transcription dna templatedGO:00063513770.147
regulation of muscle system processGO:0090257790.146
regulation of transcription from rna polymerase ii promoterGO:00063572340.144
ion transmembrane transportGO:00342203650.141
cellular ion homeostasisGO:00068731840.139
heart developmentGO:0007507720.137
response to estradiolGO:00323551640.137
regulation of muscle contractionGO:0006937530.135
cellular metal ion homeostasisGO:00068751720.134
negative regulation of macromolecule metabolic processGO:00106052600.133
cellular response to organic cyclic compoundGO:00714072020.132
regulation of neurogenesisGO:00507672470.132
cellular response to steroid hormone stimulusGO:0071383930.129
striated muscle contractionGO:0006941440.119
response to oxygen levelsGO:00704822650.115
circulatory system developmentGO:00723591340.110
positive regulation of rna biosynthetic processGO:19026801970.107
response to cytokineGO:00340972150.107
metal ion transportGO:00300012890.106
inorganic ion transmembrane transportGO:00986602290.103
positive regulation of gene expressionGO:00106282440.101
monocarboxylic acid metabolic processGO:00327871520.096
negative regulation of transcription dna templatedGO:00458921160.096
regulation of cell developmentGO:00602842630.095
regulation of multicellular organismal developmentGO:20000263760.094
enzyme linked receptor protein signaling pathwayGO:00071671160.093
blood circulationGO:00080151830.089
response to vitaminGO:00332731310.088
regulation of cell differentiationGO:00455953200.084
nucleic acid templated transcriptionGO:00976593790.083
circulatory system processGO:00030131830.077
cellular cation homeostasisGO:00300031800.077
transmembrane transportGO:00550854120.075
positive regulation of cell proliferationGO:00082842490.073
amine metabolic processGO:0009308380.070
anatomical structure morphogenesisGO:00096532980.070
muscle tissue developmentGO:0060537580.068
sodium ion transmembrane transportGO:0035725670.068
organophosphate metabolic processGO:00196373700.066
regulation of nervous system developmentGO:00519602640.065
metal ion homeostasisGO:00550651860.065
developmental inductionGO:003112820.065
positive regulation of nucleic acid templated transcriptionGO:19035081970.065
negative regulation of rna metabolic processGO:00512531230.064
response to metal ionGO:00100382530.063
positive regulation of nucleobase containing compound metabolic processGO:00459353190.063
macromolecular complex assemblyGO:00650032730.063
positive regulation of nitrogen compound metabolic processGO:00511733340.063
response to nutrient levelsGO:00316673700.062
heart morphogenesisGO:000300730.059
organonitrogen compound biosynthetic processGO:19015661670.059
cellular component movementGO:00069282480.058
positive regulation of transcription dna templatedGO:00458931970.057
response to bacteriumGO:00096172000.056
positive regulation of cytosolic calcium ion concentrationGO:00072041220.055
immune responseGO:00069551040.054
regulation of catalytic activityGO:00507903040.054
negative regulation of biosynthetic processGO:00098901680.053
negative regulation of nucleic acid templated transcriptionGO:19035071170.052
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.052
response to insulinGO:00328681330.052
positive regulation of nervous system developmentGO:00519621780.052
immune system processGO:00023762040.051
negative regulation of molecular functionGO:00440921330.051
regulation of molecular functionGO:00650093980.051
nucleoside phosphate metabolic processGO:00067532830.050
protein complex assemblyGO:00064612630.049
cellular ketone metabolic processGO:0042180510.049
cellular divalent inorganic cation homeostasisGO:00725031620.049
nucleobase containing small molecule metabolic processGO:00550863160.049
carbohydrate derivative metabolic processGO:19011353460.047
response to hypoxiaGO:00016662310.047
intracellular signal transductionGO:00355563140.046
response to lipopolysaccharideGO:00324961910.046
ribonucleotide metabolic processGO:00092592310.046
cell projection organizationGO:00300303020.046
cellular component assemblyGO:00226073600.044
positive regulation of rna metabolic processGO:00512542030.043
positive regulation of apoptotic processGO:00430651540.043
regulation of neuron differentiationGO:00456642080.043
regulation of neuron projection developmentGO:00109751610.043
central nervous system developmentGO:00074173110.043
cardiac chamber developmentGO:000320510.043
cellular homeostasisGO:00197252520.043
cellular response to peptideGO:19016531330.043
purine containing compound metabolic processGO:00725212530.042
intracellular transportGO:00469071850.041
positive regulation of transportGO:00510502450.041
cellular response to peptide hormone stimulusGO:00713751200.041
regulation of ion transportGO:00432692450.041
regulation of heart contractionGO:0008016480.040
response to corticosteroidGO:00319602350.040
cellular response to glucocorticoid stimulusGO:0071385680.040
negative regulation of neurogenesisGO:0050768780.039
actin mediated cell contractionGO:0070252120.039
regulation of cellular protein metabolic processGO:00322682670.039
positive regulation of phosphate metabolic processGO:00459372620.039
cellular response to corticosteroid stimulusGO:0071384690.038
response to external biotic stimulusGO:00432072210.038
response to molecule of bacterial originGO:00022371940.038
muscle cell differentiationGO:0042692520.037
regulation of cellular localizationGO:00603412630.037
negative regulation of signalingGO:00230571570.036
hormone secretionGO:00468791150.036
ventricular cardiac muscle cell action potentialGO:008600520.036
rhythmic processGO:00485111560.035
positive regulation of cellular biosynthetic processGO:00313282950.035
response to ammonium ionGO:0060359710.035
positive regulation of cell differentiationGO:00455972170.035
response to growth factorGO:00708481890.035
cellular response to growth factor stimulusGO:00713631620.035
transmission of nerve impulseGO:0019226420.035
cellular response to acid chemicalGO:0071229750.035
neuron projection developmentGO:00311752730.035
regulation of membrane potentialGO:00423911100.035
reproductionGO:00000032450.035
neurological system processGO:00508772190.035
muscle structure developmentGO:0061061870.034
negative regulation of cell differentiationGO:0045596990.034
agingGO:00075682410.034
cell growthGO:00160491040.033
cell cell signalingGO:00072673350.033
cellular amine metabolic processGO:0044106380.033
monovalent inorganic cation transportGO:00156721720.032
protein complex biogenesisGO:00702712630.032
negative regulation of programmed cell deathGO:00430691830.031
action potentialGO:0001508540.031
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.030
ribose phosphate metabolic processGO:00196932350.030
homeostatic processGO:00425923310.029
regulation of hormone levelsGO:00108171870.029
single organism reproductive processGO:00447022970.029
regulation of phosphate metabolic processGO:00192203490.029
response to fatty acidGO:0070542650.029
cardiac muscle contractionGO:0060048270.029
negative regulation of rna biosynthetic processGO:19026791180.028
cellular component biogenesisGO:00440853680.028
regulation of cellular ketone metabolic processGO:0010565270.028
gland developmentGO:00487321550.028
regulation of phosphorus metabolic processGO:00511743490.028
carboxylic acid biosynthetic processGO:0046394830.028
chemical homeostasisGO:00488782920.028
calcium ion homeostasisGO:00550741620.028
tissue developmentGO:00098882520.028
protein maturationGO:0051604680.028
cellular amino acid metabolic processGO:00065201070.028
fat cell proliferationGO:007034120.028
cation homeostasisGO:00550801950.028
regulation of apoptotic processGO:00429813350.027
regulation of protein localizationGO:0032880810.027
regulation of homeostatic processGO:00328441010.027
purine nucleotide metabolic processGO:00061632290.027
regulation of cell projection organizationGO:00313441750.027
cellular response to nitrogen compoundGO:19016992100.027
response to inorganic substanceGO:00100353770.027
cellular response to alkaloidGO:0071312250.027
limb morphogenesisGO:003510840.026
negative regulation of transporter activityGO:0032410130.026
response to acid chemicalGO:00011012220.026
regulation of hydrolase activityGO:00513361430.026
response to tumor necrosis factorGO:0034612560.026
negative regulation of cell communicationGO:00106481580.025
single organism biosynthetic processGO:00447113420.025
cellular chemical homeostasisGO:00550822470.025
defense responseGO:00069521940.025
ion homeostasisGO:00508012120.024
positive regulation of neurogenesisGO:00507691650.024
neuron differentiationGO:00301823680.024
angiogenesis involved in coronary vascular morphogenesisGO:006097830.024
negative regulation of cellular protein metabolic processGO:00322691060.024
protein complex subunit organizationGO:00718223020.024
heart processGO:0003015570.024
negative regulation of ion transportGO:0043271510.024
response to corticosteroneGO:0051412400.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.023
negative regulation of protein metabolic processGO:00512481140.023
single organism organelle organizationGO:19025891800.023
macromolecular complex subunit organizationGO:00439333390.023
single organism behaviorGO:00447081300.023
positive regulation of programmed cell deathGO:00430681570.023
cellular response to cytokine stimulusGO:00713451270.023
response to ethanolGO:00454711620.023
regulation of signal transductionGO:00099663180.023
cellular calcium ion homeostasisGO:00068741600.023
regulation of organ formationGO:000315620.022
positive regulation of neuron differentiationGO:00456661260.022
organic cyclic compound catabolic processGO:19013611750.022
proteolysisGO:00065081750.022
regulation of protein metabolic processGO:00512462890.022
positive regulation of homeostatic processGO:0032846490.022
smooth muscle contractionGO:0006939370.022
bmp signaling pathwayGO:003050940.021
regulation of establishment of protein localizationGO:0070201690.021
regulation of sodium ion transmembrane transporter activityGO:200064940.021
cytosolic calcium ion homeostasisGO:00514801400.021
potassium ion transmembrane transportGO:0071805710.021
heart contractionGO:0060047570.021
blood vessel developmentGO:0001568690.021
renal system developmentGO:0072001670.020
response to extracellular stimulusGO:00099913800.020
cytoplasmic transportGO:00164821150.020
neuron developmentGO:00486662860.020
fatty acid metabolic processGO:0006631990.020
negative regulation of cell deathGO:00605482290.020
cell morphogenesis involved in differentiationGO:00009041190.020
negative regulation of transportGO:00510511360.020
regulation of cell proliferationGO:00421273590.020
hematopoietic or lymphoid organ developmentGO:0048534360.020
single organism intracellular transportGO:19025821660.020
positive regulation of signalingGO:00230562700.020
regulation of ion homeostasisGO:2000021630.020
appendage morphogenesisGO:003510740.020
l glutamate importGO:005193820.020
urogenital system developmentGO:0001655780.019
nucleotide metabolic processGO:00091172790.019
regulation of programmed cell deathGO:00430673410.019
striated muscle tissue developmentGO:0014706580.019
cardiac ventricle developmentGO:000323110.019
organ morphogenesisGO:0009887750.019
protein phosphorylationGO:00064683450.019
gonad developmentGO:00084061040.019
response to campGO:0051591910.019
apoptotic processGO:00069153810.019
regulation of cellular component movementGO:00512701500.018
positive regulation of catalytic activityGO:00430851840.018
positive regulation of ion transportGO:0043270940.018
negative regulation of multicellular organismal processGO:00512412030.018
response to alkaloidGO:00432791320.018
dephosphorylationGO:0016311980.018
regulation of ion transmembrane transportGO:00347651210.018
regulation of cellular amino acid metabolic processGO:000652120.018
organelle organizationGO:00069962660.018
regulation of blood pressureGO:0008217830.017
secretionGO:00469033070.017
developmental process involved in reproductionGO:00030061590.017
vasculature developmentGO:0001944700.017
purine ribonucleotide metabolic processGO:00091502270.017
protein oligomerizationGO:00512591910.017
response to reactive oxygen speciesGO:00003021200.017
cell part morphogenesisGO:00329901230.017
cyclic nucleotide metabolic processGO:0009187800.017
regulation of canonical wnt signaling pathwayGO:006082840.017
growthGO:00400071650.017
cellular response to tumor necrosis factorGO:0071356460.017
inflammatory responseGO:00069541500.017
positive regulation of cell deathGO:00109421840.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
glial cell differentiationGO:0010001650.017
positive regulation of cellular component organizationGO:00511302000.016
regulation of purine nucleotide metabolic processGO:19005421150.016
negative regulation of protein maturationGO:1903318470.016
cell type specific apoptotic processGO:00972851340.016
response to radiationGO:00093141370.016
locomotionGO:00400112370.016
positive regulation of fat cell proliferationGO:007034610.016
regulation of protein complex assemblyGO:0043254330.016
digestive tract developmentGO:0048565390.016
glycosyl compound metabolic processGO:19016571820.016
reproductive structure developmentGO:00486081280.016
positive regulation of response to stimulusGO:00485842850.016
response to monosaccharideGO:00342841590.016
negative regulation of cell developmentGO:0010721820.016
insulin like growth factor receptor signaling pathwayGO:004800930.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
cellular response to ketoneGO:1901655510.015
protein processingGO:0016485680.015
protein transportGO:00150311320.015
organic acid biosynthetic processGO:0016053830.015
immune system developmentGO:0002520410.015
regulation of intracellular transportGO:0032386650.015
positive regulation of cardiac muscle cell proliferationGO:006004540.015
response to decreased oxygen levelsGO:00362932370.015
response to hexoseGO:00097461440.015
response to electrical stimulusGO:0051602560.015
regulation of transmembrane transportGO:00347621220.015
cellular response to stressGO:00335542690.015
multicellular organismal reproductive processGO:00486092330.015
positive regulation of brown fat cell proliferationGO:007034910.015
cell cycleGO:00070491010.015
positive regulation of neuron projection developmentGO:0010976990.015
kidney developmentGO:0001822670.015
regulation of system processGO:00440572080.015
purine nucleoside metabolic processGO:00422781690.015
ras protein signal transductionGO:0007265290.015
multicellular organismal signalingGO:0035637440.015
coronary vasculature morphogenesisGO:006097730.014
regulation of amine transportGO:0051952540.014
regulation of catecholamine secretionGO:0050433320.014
inflammatory response to antigenic stimulusGO:0002437180.014
heterocycle catabolic processGO:00467001670.014
regulation of cellular component organizationGO:00511283680.014
gamete generationGO:00072761240.014
regulation of vasculature developmentGO:1901342440.014
protein dephosphorylationGO:0006470380.014
organic hydroxy compound metabolic processGO:19016151150.014
icosanoid metabolic processGO:0006690380.014
embryonic appendage morphogenesisGO:003511340.014
response to biotic stimulusGO:00096072260.014
negative regulation of catalytic activityGO:00430861030.014
axis specificationGO:000979840.014
embryonic limb morphogenesisGO:003032640.014
learning or memoryGO:0007611900.014
muscle cell proliferationGO:0033002840.014
organic substance catabolic processGO:19015753160.014
positive regulation of cellular amine metabolic processGO:003324030.014
cellular potassium ion transportGO:0071804720.014
dna metabolic processGO:0006259960.014
positive regulation of cell projection organizationGO:00313461110.014
cellular response to insulin stimulusGO:0032869810.014
multicellular organism growthGO:003526410.014
small molecule biosynthetic processGO:00442831240.014
glomerular mesangium developmentGO:007210940.013
regulation of cellular amine metabolic processGO:003323880.013
reproductive system developmentGO:00614581280.013
response to ketoneGO:19016541820.013
establishment of protein localizationGO:00451841410.013
response to vitamin aGO:0033189360.013
glomerular mesangial cell proliferationGO:007211040.013
negative regulation of developmental processGO:00510931250.013
organ inductionGO:000175910.013
mapk cascadeGO:00001651400.013
macromolecule localizationGO:00330362520.013
cellular component morphogenesisGO:00329891550.013
multicellular organism reproductionGO:00325042330.013
regulation of nucleotide metabolic processGO:00061401170.013
muscle tissue morphogenesisGO:006041510.013
lipid storageGO:001991510.013
smooth muscle cell proliferationGO:0048659770.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
negative regulation of cell proliferationGO:00082851190.013
positive regulation of molecular functionGO:00440932300.013
acid secretionGO:0046717480.013
reproductive processGO:00224143720.013
actin cytoskeleton organizationGO:0030036730.012
regulation of smooth muscle contractionGO:0006940290.012
cardiac muscle cell contractionGO:0086003100.012
secretion by cellGO:00329402480.012
negative regulation of apoptotic processGO:00430661810.012
cellular response to alcoholGO:0097306870.012
regulation of neuron deathGO:19012141150.012
regulation of neuron apoptotic processGO:0043523830.012
divalent inorganic cation homeostasisGO:00725071650.012
regenerationGO:00310991630.012
cellular nitrogen compound catabolic processGO:00442701630.012
response to woundingGO:00096112540.012
response to amino acidGO:0043200750.012
regulation of blood circulationGO:19035221100.012
regulation of ion transmembrane transporter activityGO:0032412480.012
regulation of transmembrane transporter activityGO:0022898490.012
nucleotide biosynthetic processGO:0009165980.012
gliogenesisGO:0042063930.012
organophosphate biosynthetic processGO:00904071430.012
response to oxidative stressGO:00069791860.012
positive regulation of immune responseGO:0050778420.012
hemopoiesisGO:0030097340.011
defense response to gram negative bacteriumGO:005082930.011
negative regulation of secretionGO:0051048820.011
response to mechanical stimulusGO:00096121340.011
circadian rhythmGO:0007623880.011
negative regulation of ion transmembrane transporter activityGO:0032413120.011
g protein coupled receptor signaling pathwayGO:00071862420.011
negative regulation of neuron differentiationGO:0045665620.011
response to carbohydrateGO:00097431830.011
small gtpase mediated signal transductionGO:0007264360.011
negative regulation of signal transductionGO:0009968830.011
mammary gland developmentGO:0030879380.011
positive regulation of cell developmentGO:00107201760.011
neuronal action potentialGO:0019228350.011
synaptic transmission glutamatergicGO:0035249330.011
epithelium developmentGO:0060429960.011
positive regulation of ion transmembrane transportGO:0034767240.011
catecholamine transportGO:0051937370.011
muscle organ morphogenesisGO:004864410.011
calcium ion transportGO:00068161310.011
behaviorGO:00076102050.011
brain developmentGO:00074202470.011
maintenance of locationGO:0051235170.011
multi multicellular organism processGO:00447061380.011
regulation of gtpase activityGO:0043087570.010
memoryGO:0007613540.010
nucleobase containing compound catabolic processGO:00346551520.010
actin filament based processGO:0030029860.010
response to transition metal nanoparticleGO:19902671220.010
spermatogenesisGO:0007283990.010
catabolic processGO:00090563510.010
response to axon injuryGO:0048678590.010
regulation of brown fat cell proliferationGO:007034710.010
dna replicationGO:0006260370.010
regulation of fatty acid metabolic processGO:0019217180.010
forebrain developmentGO:0030900980.010
response to heatGO:0009408600.010
negative regulation of hormone secretionGO:0046888460.010
cellular response to molecule of bacterial originGO:0071219560.010
regulation of transferase activityGO:00513381230.010
positive regulation of cell communicationGO:00106472710.010

Plb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
musculoskeletal system diseaseDOID:1700.048
nervous system diseaseDOID:86300.031
cardiovascular system diseaseDOID:128700.021
heart diseaseDOID:11400.011
muscle tissue diseaseDOID:6600.010
myopathyDOID:42300.010
muscular diseaseDOID:008000000.010