Rattus norvegicus

37 known processes

Ldhb

lactate dehydrogenase B

(Aliases: Ldh2)

Ldhb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.541
monocarboxylic acid metabolic processGO:00327871520.398
carboxylic acid metabolic processGO:00197522890.374
single organism biosynthetic processGO:00447113420.270
organic acid metabolic processGO:00060822920.232
nucleoside monophosphate metabolic processGO:0009123930.224
organophosphate metabolic processGO:00196373700.206
fatty acid metabolic processGO:0006631990.156
cellular amino acid biosynthetic processGO:0008652320.146
homeostatic processGO:00425923310.138
response to peptide hormoneGO:00434342780.129
regulation of phosphorus metabolic processGO:00511743490.125
lipid oxidationGO:0034440300.122
circulatory system developmentGO:00723591340.122
response to nutrient levelsGO:00316673700.118
Rat
nucleotide metabolic processGO:00091172790.118
response to bacteriumGO:00096172000.114
anion transportGO:00068201780.108
nucleoside metabolic processGO:00091161790.107
lipid biosynthetic processGO:00086101280.105
nucleoside phosphate metabolic processGO:00067532830.105
ion homeostasisGO:00508012120.101
oxidation reduction processGO:00551143040.096
generation of precursor metabolites and energyGO:0006091620.094
response to lipopolysaccharideGO:00324961910.091
organic substance catabolic processGO:19015753160.085
intracellular signal transductionGO:00355563140.080
cellular chemical homeostasisGO:00550822470.080
single organism catabolic processGO:00447122830.079
cation transportGO:00068123820.077
response to peptideGO:19016522920.075
cellular lipid metabolic processGO:00442552080.074
inorganic cation transmembrane transportGO:00986622020.073
metal ion homeostasisGO:00550651860.072
cellular homeostasisGO:00197252520.071
cell cell signalingGO:00072673350.071
cellular ion homeostasisGO:00068731840.070
response to corticosteroidGO:00319602350.070
monocarboxylic acid catabolic processGO:0072329280.068
response to starvationGO:0042594590.068
organophosphate biosynthetic processGO:00904071430.067
transmembrane transportGO:00550854120.063
nucleobase containing small molecule metabolic processGO:00550863160.062
protein complex biogenesisGO:00702712630.062
chemical homeostasisGO:00488782920.062
carbohydrate derivative metabolic processGO:19011353460.061
response to hypoxiaGO:00016662310.059
Rat
purine containing compound metabolic processGO:00725212530.059
regulation of multicellular organismal developmentGO:20000263760.059
organic acid biosynthetic processGO:0016053830.058
cofactor metabolic processGO:0051186950.058
negative regulation of multicellular organismal processGO:00512412030.058
purine nucleoside metabolic processGO:00422781690.057
fatty acid oxidationGO:0019395290.057
positive regulation of nitrogen compound metabolic processGO:00511733340.054
inorganic ion transmembrane transportGO:00986602290.054
cation homeostasisGO:00550801950.054
response to cytokineGO:00340972150.053
behaviorGO:00076102050.053
central nervous system developmentGO:00074173110.052
response to temperature stimulusGO:0009266940.051
protein complex assemblyGO:00064612630.050
purine ribonucleoside metabolic processGO:00461281680.050
regulation of cellular component organizationGO:00511283680.050
cellular metal ion homeostasisGO:00068751720.050
apoptotic processGO:00069153810.050
Rat
regulation of phosphorylationGO:00423252480.049
nucleoside triphosphate metabolic processGO:00091411440.048
energy derivation by oxidation of organic compoundsGO:0015980460.048
lipid metabolic processGO:00066292830.048
sodium ion transmembrane transportGO:0035725670.048
response to biotic stimulusGO:00096072260.048
monovalent inorganic cation transportGO:00156721720.047
single organism carbohydrate metabolic processGO:00447231180.047
small molecule biosynthetic processGO:00442831240.047
response to other organismGO:00517072200.046
carboxylic acid biosynthetic processGO:0046394830.046
cellular cation homeostasisGO:00300031800.045
nicotinamide nucleotide metabolic processGO:0046496280.045
regulation of phosphate metabolic processGO:00192203490.045
cation transmembrane transportGO:00986552630.044
regulation of ion transportGO:00432692450.044
fatty acid beta oxidationGO:0006635220.043
carbohydrate catabolic processGO:0016052400.043
organophosphate catabolic processGO:00464341480.043
cold acclimationGO:000963110.043
cellular divalent inorganic cation homeostasisGO:00725031620.042
purine nucleotide biosynthetic processGO:0006164830.042
response to external biotic stimulusGO:00432072210.042
anatomical structure morphogenesisGO:00096532980.042
Fly
positive regulation of phosphorus metabolic processGO:00105622620.042
response to oxygen levelsGO:00704822650.042
Rat
neurotransmitter uptakeGO:000150430.042
agingGO:00075682410.041
positive regulation of signalingGO:00230562700.041
cellular amino acid metabolic processGO:00065201070.041
negative regulation of cellular metabolic processGO:00313242810.040
organic anion transportGO:00157111320.040
catabolic processGO:00090563510.040
response to campGO:0051591910.039
Rat
ribonucleoside metabolic processGO:00091191740.038
carboxylic acid catabolic processGO:0046395490.038
divalent inorganic cation homeostasisGO:00725071650.037
cellular component biogenesisGO:00440853680.037
carbohydrate metabolic processGO:00059751300.037
response to nutrientGO:00075842480.037
Rat
response to glucocorticoidGO:00513842230.037
coenzyme metabolic processGO:0006732860.037
response to purine containing compoundGO:00140741260.037
Rat
cellular response to nitrogen compoundGO:19016992100.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
negative regulation of developmental processGO:00510931250.036
cellular component movementGO:00069282480.036
negative regulation of metabolic processGO:00098923310.035
response to insulinGO:00328681330.034
localization of cellGO:00516742020.034
organelle organizationGO:00069962660.034
response to carbohydrateGO:00097431830.034
Rat
cellular component assemblyGO:00226073600.034
regulation of cell proliferationGO:00421273590.034
response to decreased oxygen levelsGO:00362932370.034
Rat
glutamine family amino acid biosynthetic processGO:000908420.033
positive regulation of intracellular signal transductionGO:19025331380.033
regulation of neurotransmitter levelsGO:0001505420.033
metal ion transportGO:00300012890.033
heart morphogenesisGO:000300730.033
brain developmentGO:00074202470.032
cellular amine metabolic processGO:0044106380.032
secretionGO:00469033070.032
positive regulation of cell communicationGO:00106472710.031
cellular response to stressGO:00335542690.031
purine ribonucleotide metabolic processGO:00091502270.031
response to coldGO:0009409290.031
organic acid transportGO:00158491160.031
ion transmembrane transportGO:00342203650.031
response to heatGO:0009408600.031
cellular catabolic processGO:00442482950.031
anion transmembrane transportGO:0098656770.030
purine nucleoside biosynthetic processGO:0042451210.030
response to extracellular stimulusGO:00099913800.030
Rat
programmed cell deathGO:00125013920.030
Rat
response to monosaccharideGO:00342841590.030
Rat
positive regulation of cell proliferationGO:00082842490.029
purine nucleotide metabolic processGO:00061632290.029
protein oligomerizationGO:00512591910.029
signal transduction by phosphorylationGO:00230141440.029
response to acid chemicalGO:00011012220.029
macromolecular complex subunit organizationGO:00439333390.029
glycosyl compound metabolic processGO:19016571820.029
ribose phosphate metabolic processGO:00196932350.028
response to oxidative stressGO:00069791860.028
Rat
regulation of secretionGO:00510462240.028
sequestering of calcium ionGO:005120880.028
regulation of apoptotic processGO:00429813350.028
Rat
regulation of cellular ketone metabolic processGO:0010565270.028
signal releaseGO:00230611450.028
regulation of system processGO:00440572080.028
cellular response to organonitrogen compoundGO:00714171970.027
regulation of protein modification processGO:00313991940.027
protein phosphorylationGO:00064683450.027
cell projection organizationGO:00300303020.027
cellular calcium ion homeostasisGO:00068741600.027
regulation of purine nucleotide metabolic processGO:19005421150.027
regulation of atp biosynthetic processGO:200116920.027
regulation of membrane potentialGO:00423911100.026
reproductive processGO:00224143720.026
carboxylic acid transportGO:00469421150.026
positive regulation of cell deathGO:00109421840.026
Rat
regulation of cellular amine metabolic processGO:003323880.026
calcium ion homeostasisGO:00550741620.025
response to organophosphorusGO:00466831020.025
Rat
adenine nucleotide transportGO:005150320.025
head developmentGO:00603222470.025
oxaloacetate metabolic processGO:000610760.025
growthGO:00400071650.025
regulation of cell differentiationGO:00455953200.025
organic acid catabolic processGO:0016054490.024
regulation of cell projection organizationGO:00313441750.024
cardiovascular system developmentGO:00723581340.024
response to molecule of bacterial originGO:00022371940.024
positive regulation of molecular functionGO:00440932300.024
sodium ion transportGO:0006814820.024
amine metabolic processGO:0009308380.024
monocarboxylic acid transportGO:0015718520.024
purine ribonucleoside triphosphate catabolic processGO:00092071220.024
oxidoreduction coenzyme metabolic processGO:0006733310.024
regulation of molecular functionGO:00650093980.024
response to woundingGO:00096112540.024
neuron differentiationGO:00301823680.024
response to metal ionGO:00100382530.023
acrosome assemblyGO:000167530.023
cytosolic calcium ion homeostasisGO:00514801400.023
positive regulation of transportGO:00510502450.023
negative regulation of cell deathGO:00605482290.023
glycogen metabolic processGO:0005977230.023
organonitrogen compound biosynthetic processGO:19015661670.023
positive regulation of ion transportGO:0043270940.023
regulation of anatomical structure morphogenesisGO:00226031410.023
divalent metal ion transportGO:00708381320.023
regulation of hydrolase activityGO:00513361430.023
single organism organelle organizationGO:19025891800.023
single organism carbohydrate catabolic processGO:0044724400.023
response to amino acidGO:0043200750.023
purine containing compound catabolic processGO:00725231380.022
cellular ketone metabolic processGO:0042180510.022
regulation of cellular amino acid metabolic processGO:000652120.022
ribose phosphate biosynthetic processGO:0046390870.022
reproductionGO:00000032450.022
neuron projection developmentGO:00311752730.021
cellular response to endogenous stimulusGO:00714953770.021
polysaccharide metabolic processGO:0005976250.021
positive regulation of cellular biosynthetic processGO:00313282950.021
response to ethanolGO:00454711620.021
positive regulation of cellular amine metabolic processGO:003324030.021
fatty acid catabolic processGO:0009062260.021
regulation of cellular localizationGO:00603412630.020
cellular lipid catabolic processGO:0044242370.020
nucleoside phosphate catabolic processGO:19012921400.020
positive regulation of hydrolase activityGO:0051345860.020
secretion by cellGO:00329402480.020
protein complex subunit organizationGO:00718223020.020
cell migrationGO:00164771970.020
response to inorganic substanceGO:00100353770.020
Rat
heterocycle catabolic processGO:00467001670.020
positive regulation of neuron projection developmentGO:0010976990.020
lipid catabolic processGO:0016042460.020
positive regulation of response to stimulusGO:00485842850.020
ras protein signal transductionGO:0007265290.020
ribonucleotide metabolic processGO:00092592310.020
divalent inorganic cation transportGO:00725111340.020
dicarboxylic acid metabolic processGO:0043648420.020
cellular response to organic cyclic compoundGO:00714072020.020
purine nucleoside monophosphate metabolic processGO:0009126840.019
regulation of nervous system developmentGO:00519602640.019
regulation of catalytic activityGO:00507903040.019
regulation of reactive oxygen species metabolic processGO:2000377260.019
nad metabolic processGO:0019674150.019
regulation of programmed cell deathGO:00430673410.019
Rat
developmental growthGO:00485891000.019
neuron apoptotic processGO:0051402880.019
regulation of hormone levelsGO:00108171870.019
positive regulation of multicellular organismal processGO:00512403870.019
cellular glucan metabolic processGO:0006073230.019
positive regulation of atp biosynthetic processGO:200117120.019
intracellular transportGO:00469071850.018
pyridine containing compound metabolic processGO:0072524320.018
regulation of nucleotide metabolic processGO:00061401170.018
response to alkaloidGO:00432791320.018
macromolecular complex assemblyGO:00650032730.018
developmental process involved in reproductionGO:00030061590.018
cell motilityGO:00488702020.018
positive regulation of secretion by cellGO:19035321280.018
regulation of muscle system processGO:0090257790.018
gland developmentGO:00487321550.018
cellular response to insulin stimulusGO:0032869810.018
regulation of blood circulationGO:19035221100.018
negative regulation of macromolecule metabolic processGO:00106052600.018
regulation of metal ion transportGO:00109591180.018
regenerationGO:00310991630.018
negative regulation of cell differentiationGO:0045596990.018
macromolecule localizationGO:00330362520.018
cellular response to external stimulusGO:00714961180.018
cell growthGO:00160491040.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
regulation of protein metabolic processGO:00512462890.017
nitrogen compound transportGO:00717052290.017
purine ribonucleoside monophosphate metabolic processGO:0009167840.017
response to reactive oxygen speciesGO:00003021200.017
Rat
locomotionGO:00400112370.017
cell cycle checkpointGO:000007520.017
response to mechanical stimulusGO:00096121340.017
dna integrity checkpointGO:003157020.017
heme biosynthetic processGO:000678340.017
small gtpase mediated signal transductionGO:0007264360.017
l glutamate importGO:005193820.017
positive regulation of cellular component organizationGO:00511302000.017
positive regulation of nucleotide metabolic processGO:0045981910.017
blood circulationGO:00080151830.017
positive regulation of signal transductionGO:00099671750.017
response to hydrogen peroxideGO:0042542890.017
Rat
lipid localizationGO:0010876620.017
synaptic transmissionGO:00072682350.017
single organism behaviorGO:00447081300.016
glucose metabolic processGO:0006006520.016
multicellular organism reproductionGO:00325042330.016
actin filament based processGO:0030029860.016
cell cell signaling involved in cell fate commitmentGO:004516820.016
purine ribonucleoside biosynthetic processGO:0046129210.016
regulation of homeostatic processGO:00328441010.016
ribonucleotide biosynthetic processGO:0009260850.016
regulation of transmembrane transportGO:00347621220.016
monocarboxylic acid biosynthetic processGO:0072330480.016
response to estrogenGO:00436272320.016
Rat
necroptotic processGO:007026620.016
mapk cascadeGO:00001651400.016
multicellular organismal reproductive processGO:00486092330.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
muscle contractionGO:0006936880.015
regulation of signal transductionGO:00099663180.015
carbohydrate derivative biosynthetic processGO:19011371240.015
regulation of mapk cascadeGO:00434081160.015
adult locomotory behaviorGO:000834440.015
nadh metabolic processGO:0006734100.015
response to ketoneGO:19016541820.015
purine ribonucleotide biosynthetic processGO:0009152810.015
response to hexoseGO:00097461440.015
Rat
cellular response to oxygen containing compoundGO:19017013860.015
development of primary sexual characteristicsGO:00451371070.015
protein heterooligomerizationGO:0051291890.015
regulation of synaptic transmissionGO:00508041410.015
nucleoside triphosphate catabolic processGO:00091431230.015
regulation of smooth muscle cell proliferationGO:0048660750.015
amino acid transportGO:0006865700.015
negative regulation of apoptotic processGO:00430661810.014
positive regulation of developmental processGO:00510942830.014
circulatory system processGO:00030131830.014
cytoskeleton organizationGO:00070101110.014
g protein coupled receptor signaling pathwayGO:00071862420.014
maintenance of locationGO:0051235170.014
regulation of nucleotide biosynthetic processGO:0030808470.014
striated muscle tissue developmentGO:0014706580.014
alpha amino acid biosynthetic processGO:1901607230.014
regulation of cell growthGO:0001558850.014
energy reserve metabolic processGO:0006112250.014
ribonucleoside monophosphate metabolic processGO:0009161880.014
nucleotide biosynthetic processGO:0009165980.014
liver developmentGO:0001889900.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
small molecule catabolic processGO:0044282590.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
Fly
regulation of protein phosphorylationGO:00019321830.014
organonitrogen compound catabolic processGO:19015651790.014
response to fatty acidGO:0070542650.014
transcription from rna polymerase ii promoterGO:00063662520.013
regulation of intracellular signal transductionGO:19025312180.013
intestinal absorptionGO:005089230.013
response to radiationGO:00093141370.013
rhythmic processGO:00485111560.013
multi organism reproductive processGO:00447032620.013
protein tetramerizationGO:0051262380.013
dicarboxylic acid transportGO:0006835340.013
negative regulation of protein metabolic processGO:00512481140.013
regulation of cell developmentGO:00602842630.013
reactive oxygen species metabolic processGO:0072593370.013
lipid transportGO:0006869610.013
neuron developmentGO:00486662860.013
calcium ion transmembrane transportGO:0070588700.013
negative regulation of cell cycle phase transitionGO:190198840.013
hepaticobiliary system developmentGO:0061008900.013
regulation of neuron differentiationGO:00456642080.013
amide transportGO:00428861050.013
heart contractionGO:0060047570.013
cellular carbohydrate metabolic processGO:0044262720.013
sexual reproductionGO:00199531480.013
respiratory system processGO:000301630.013
muscle system processGO:00030121150.013
regulation of transferase activityGO:00513381230.013
calcium ion transportGO:00068161310.013
positive regulation of cell differentiationGO:00455972170.013
regulation of growthGO:00400081050.013
regulation of cellular component movementGO:00512701500.013
regulation of secretion by cellGO:19035302080.013
positive regulation of neuron differentiationGO:00456661260.013
cellular nitrogen compound catabolic processGO:00442701630.012
regulation of transporter activityGO:0032409500.012
action potentialGO:0001508540.012
neuromuscular processGO:005090520.012
response to transition metal nanoparticleGO:19902671220.012
axis specificationGO:000979840.012
positive regulation of apoptotic processGO:00430651540.012
Rat
response to nicotineGO:0035094510.012
blood vessel morphogenesisGO:0048514580.012
nucleotide catabolic processGO:00091661390.012
protein homotetramerizationGO:0051289250.012
tissue developmentGO:00098882520.012
negative regulation of molecular functionGO:00440921330.012
blood vessel developmentGO:0001568690.012
positive regulation of homeostatic processGO:0032846490.012
aerobic respirationGO:0009060130.012
gamete generationGO:00072761240.012
negative regulation of programmed cell deathGO:00430691830.012
positive regulation of programmed cell deathGO:00430681570.012
Rat
nucleoside phosphate biosynthetic processGO:19012931020.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
purine containing compound biosynthetic processGO:0072522850.012
response to toxic substanceGO:00096361330.012
defense responseGO:00069521940.011
positive regulation of phosphorylationGO:00423271770.011
response to estradiolGO:00323551640.011
positive regulation of phosphate metabolic processGO:00459372620.011
glucan biosynthetic processGO:0009250150.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
negative regulation of gene expressionGO:00106291990.011
smooth muscle cell proliferationGO:0048659770.011
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of catalytic activityGO:00430851840.011
response to glucoseGO:00097491360.011
Rat
carbohydrate biosynthetic processGO:0016051420.011
negative regulation of cellular protein metabolic processGO:00322691060.011
angiogenesisGO:0001525530.011
protein homooligomerizationGO:0051260910.011
negative regulation of catalytic activityGO:00430861030.011
negative regulation of cell proliferationGO:00082851190.011
glutamate metabolic processGO:000653630.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
cellular response to abiotic stimulusGO:0071214850.011
chemotaxisGO:0006935660.011
regulation of hormone secretionGO:00468831060.011
organ regenerationGO:00311001010.011
heart developmentGO:0007507720.011
glucose homeostasisGO:0042593750.011
regulation of ion transmembrane transportGO:00347651210.011
regulation of peptide transportGO:0090087870.011
carbohydrate derivative catabolic processGO:19011361470.011
regulation of calcium ion transportGO:0051924770.011
neurological system processGO:00508772190.011
lipid storageGO:001991510.011
negative regulation of phosphorus metabolic processGO:0010563800.010
muscle structure developmentGO:0061061870.010
Fly
negative regulation of phosphate metabolic processGO:0045936800.010
purine ribonucleoside catabolic processGO:00461301240.010
carbohydrate homeostasisGO:0033500750.010
purine ribonucleoside monophosphate biosynthetic processGO:0009168200.010
ribonucleoside catabolic processGO:00424541260.010
single organism reproductive processGO:00447022970.010
regulation of cellular protein metabolic processGO:00322682670.010
neuronal action potentialGO:0019228350.010
regulation of ion homeostasisGO:2000021630.010
cytoplasmic transportGO:00164821150.010

Ldhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.044
disease of metabolismDOID:001466700.041
inherited metabolic disorderDOID:65500.029
central nervous system diseaseDOID:33100.016
sensory system diseaseDOID:005015500.016
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
musculoskeletal system diseaseDOID:1700.011