Rattus norvegicus

0 known processes

Mknk2

MAP kinase-interacting serine/threonine kinase 2

Mknk2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.159
rna metabolic processGO:00160704060.122
regulation of cellular protein metabolic processGO:00322682670.095
Rat
rna biosynthetic processGO:00327743800.091
response to peptideGO:19016522920.088
cellular amino acid metabolic processGO:00065201070.083
lipid metabolic processGO:00066292830.076
regulation of nucleic acid templated transcriptionGO:19035063800.075
intracellular signal transductionGO:00355563140.075
Human Mouse Fly
immune system processGO:00023762040.075
Human
regulation of cellular catabolic processGO:00313291010.075
regulation of catalytic activityGO:00507903040.071
agingGO:00075682410.070
negative regulation of cellular metabolic processGO:00313242810.068
transcription dna templatedGO:00063513770.066
catabolic processGO:00090563510.066
regulation of protein metabolic processGO:00512462890.063
Rat
negative regulation of macromolecule metabolic processGO:00106052600.062
single organism catabolic processGO:00447122830.061
nucleic acid templated transcriptionGO:00976593790.061
protein phosphorylationGO:00064683450.059
Human Mouse Rat Fly
regulation of protein phosphorylationGO:00019321830.058
macromolecule localizationGO:00330362520.056
regulation of cell developmentGO:00602842630.054
regulation of phosphorylationGO:00423252480.053
regulation of anatomical structure morphogenesisGO:00226031410.053
regulation of protein modification processGO:00313991940.053
positive regulation of protein modification processGO:00314011420.052
oxoacid metabolic processGO:00434362900.052
carboxylic acid metabolic processGO:00197522890.052
nucleoside metabolic processGO:00091161790.050
positive regulation of nitrogen compound metabolic processGO:00511733340.049
ribonucleotide metabolic processGO:00092592310.048
store operated calcium entryGO:000211520.048
small molecule biosynthetic processGO:00442831240.046
regulation of phosphorus metabolic processGO:00511743490.046
regulation of cell differentiationGO:00455953200.046
negative regulation of metabolic processGO:00098923310.045
organophosphate metabolic processGO:00196373700.045
neuron differentiationGO:00301823680.045
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.045
regulation of multicellular organismal developmentGO:20000263760.045
nucleotide catabolic processGO:00091661390.043
purine nucleoside triphosphate metabolic processGO:00091441410.043
response to peptide hormoneGO:00434342780.042
nucleobase containing small molecule metabolic processGO:00550863160.041
positive regulation of phosphate metabolic processGO:00459372620.041
organic acid metabolic processGO:00060822920.041
negative regulation of phosphorus metabolic processGO:0010563800.041
neurological system processGO:00508772190.040
positive regulation of gene expressionGO:00106282440.039
establishment of protein localizationGO:00451841410.039
ribonucleoside metabolic processGO:00091191740.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
organic acid biosynthetic processGO:0016053830.038
regulation of catabolic processGO:00098941130.038
response to ketoneGO:19016541820.037
nucleotide metabolic processGO:00091172790.037
regulation of cellular ketone metabolic processGO:0010565270.037
regulation of neurogenesisGO:00507672470.037
organonitrogen compound catabolic processGO:19015651790.037
regulation of rna biosynthetic processGO:20011413810.036
ribose phosphate metabolic processGO:00196932350.036
cellular component assemblyGO:00226073600.035
nucleoside phosphate metabolic processGO:00067532830.035
cellular ketone metabolic processGO:0042180510.035
regulation of phosphate metabolic processGO:00192203490.035
cellular response to organonitrogen compoundGO:00714171970.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
cellular response to peptideGO:19016531330.035
negative regulation of cellular protein metabolic processGO:00322691060.035
positive regulation of molecular functionGO:00440932300.035
protein localizationGO:00081041910.035
apoptotic processGO:00069153810.034
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051400.034
tissue developmentGO:00098882520.034
regulation of rna metabolic processGO:00512523910.034
regulation of intracellular signal transductionGO:19025312180.034
Fly
cellular component movementGO:00069282480.034
programmed cell deathGO:00125013920.034
Mouse
circulatory system developmentGO:00723591340.033
cellular macromolecule localizationGO:00707271220.033
single organism biosynthetic processGO:00447113420.033
cellular response to stressGO:00335542690.033
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.033
cellular response to endogenous stimulusGO:00714953770.032
purine containing compound metabolic processGO:00725212530.032
positive regulation of biosynthetic processGO:00098913190.032
regulation of lipid metabolic processGO:0019216680.032
regulation of cell proliferationGO:00421273590.032
regulation of signal transductionGO:00099663180.032
Fly
small gtpase mediated signal transductionGO:0007264360.032
Fly
carbohydrate derivative metabolic processGO:19011353460.032
coenzyme metabolic processGO:0006732860.031
multi organism reproductive processGO:00447032620.031
purine ribonucleotide metabolic processGO:00091502270.031
regulation of cellular component organizationGO:00511283680.031
response to woundingGO:00096112540.031
response to reactive oxygen speciesGO:00003021200.031
organic substance catabolic processGO:19015753160.031
carbohydrate derivative catabolic processGO:19011361470.031
negative regulation of cellular biosynthetic processGO:00313271610.031
ras protein signal transductionGO:0007265290.030
Fly
regulation of protein transportGO:0051223680.030
regulation of cellular amino acid metabolic processGO:000652120.030
glycosyl compound metabolic processGO:19016571820.030
nucleoside phosphate catabolic processGO:19012921400.029
anatomical structure morphogenesisGO:00096532980.029
regulation of transcription dna templatedGO:00063553740.029
cellular lipid metabolic processGO:00442552080.029
positive regulation of cell communicationGO:00106472710.029
cellular response to oxygen containing compoundGO:19017013860.029
metal ion transportGO:00300012890.029
purine nucleotide metabolic processGO:00061632290.029
nucleoside catabolic processGO:00091641260.028
negative regulation of protein metabolic processGO:00512481140.028
cofactor metabolic processGO:0051186950.028
negative regulation of molecular functionGO:00440921330.028
cellular response to nitrogen compoundGO:19016992100.028
cellular amine metabolic processGO:0044106380.028
response to nutrient levelsGO:00316673700.028
regulation of membrane potentialGO:00423911100.027
positive regulation of cellular protein metabolic processGO:00322701670.027
response to extracellular stimulusGO:00099913800.027
response to metal ionGO:00100382530.027
intracellular protein transportGO:0006886790.027
regulation of cellular localizationGO:00603412630.027
negative regulation of rna metabolic processGO:00512531230.027
aromatic compound catabolic processGO:00194391680.027
cellular response to hormone stimulusGO:00328702470.027
positive regulation of rna metabolic processGO:00512542030.027
regulation of kinase activityGO:00435491170.026
heterocycle catabolic processGO:00467001670.026
amine metabolic processGO:0009308380.026
response to lipopolysaccharideGO:00324961910.026
positive regulation of signalingGO:00230562700.026
response to growth factorGO:00708481890.026
multi multicellular organism processGO:00447061380.026
macromolecular complex subunit organizationGO:00439333390.026
reproductive processGO:00224143720.026
regulation of neuron differentiationGO:00456642080.025
regulation of nucleoside metabolic processGO:0009118660.025
response to estrogenGO:00436272320.025
positive regulation of protein phosphorylationGO:00019341350.024
ribonucleoside catabolic processGO:00424541260.024
negative regulation of nervous system developmentGO:0051961790.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
establishment of tissue polarityGO:000716420.024
organelle organizationGO:00069962660.024
behaviorGO:00076102050.024
protein complex subunit organizationGO:00718223020.024
ribonucleoside triphosphate catabolic processGO:00092031220.023
cellular nitrogen compound catabolic processGO:00442701630.023
muscle structure developmentGO:0061061870.023
response to acid chemicalGO:00011012220.023
positive regulation of catalytic activityGO:00430851840.023
defense responseGO:00069521940.023
regulation of small gtpase mediated signal transductionGO:0051056480.022
Fly
cell migrationGO:00164771970.022
lipid biosynthetic processGO:00086101280.022
signal transduction by phosphorylationGO:00230141440.022
negative regulation of gene expressionGO:00106291990.022
response to oxidative stressGO:00069791860.022
cellular response to peptide hormone stimulusGO:00713751200.022
protein complex assemblyGO:00064612630.022
negative regulation of cell differentiationGO:0045596990.022
peptide biosynthetic processGO:004304330.022
positive regulation of transcription dna templatedGO:00458931970.022
nucleoside triphosphate metabolic processGO:00091411440.022
regulation of protein kinase activityGO:00458591050.022
transcription from rna polymerase ii promoterGO:00063662520.021
regulation of cell projection organizationGO:00313441750.021
negative regulation of transcription dna templatedGO:00458921160.021
negative regulation of phosphate metabolic processGO:0045936800.021
regulation of cellular amine metabolic processGO:003323880.021
positive regulation of phosphorylationGO:00423271770.021
organic cyclic compound catabolic processGO:19013611750.021
negative regulation of developmental processGO:00510931250.021
gtp catabolic processGO:0006184710.021
negative regulation of cell deathGO:00605482290.020
positive regulation of response to stimulusGO:00485842850.020
ribonucleoside triphosphate metabolic processGO:00091991410.020
response to insulinGO:00328681330.020
regulation of transferase activityGO:00513381230.020
response to inorganic substanceGO:00100353770.020
cellular response to reactive oxygen speciesGO:0034614550.019
locomotionGO:00400112370.019
response to nutrientGO:00075842480.019
cellular catabolic processGO:00442482950.019
peptidyl amino acid modificationGO:00181931260.019
Rat
nucleobase containing compound catabolic processGO:00346551520.019
organophosphate catabolic processGO:00464341480.019
reproductionGO:00000032450.019
ribonucleotide catabolic processGO:00092611360.019
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
response to cadmium ionGO:0046686350.019
positive regulation of cellular biosynthetic processGO:00313282950.019
lipid localizationGO:0010876620.019
positive regulation of programmed cell deathGO:00430681570.019
proteolysisGO:00065081750.019
tube developmentGO:0035295890.019
purine ribonucleoside catabolic processGO:00461301240.018
macromolecular complex assemblyGO:00650032730.018
wound healingGO:00420601220.018
regulation of cellular component movementGO:00512701500.018
negative regulation of biosynthetic processGO:00098901680.018
positive regulation of phosphorus metabolic processGO:00105622620.018
brain developmentGO:00074202470.018
homeostatic processGO:00425923310.018
localization of cellGO:00516742020.018
multicellular organismal signalingGO:0035637440.018
positive regulation of multicellular organismal processGO:00512403870.018
protein localization to organelleGO:0033365570.018
cellular protein localizationGO:00346131220.018
regulation of gtpase activityGO:0043087570.018
regulation of nervous system developmentGO:00519602640.018
cell projection organizationGO:00300303020.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
ion transmembrane transportGO:00342203650.018
neuron projection developmentGO:00311752730.018
multicellular organism reproductionGO:00325042330.018
positive regulation of catabolic processGO:0009896780.017
cell motilityGO:00488702020.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
response to ethanolGO:00454711620.017
positive regulation of transportGO:00510502450.017
purine nucleoside metabolic processGO:00422781690.017
positive regulation of cellular component organizationGO:00511302000.017
cellular chemical homeostasisGO:00550822470.017
purine containing compound catabolic processGO:00725231380.017
single organism carbohydrate metabolic processGO:00447231180.017
regulation of protein localizationGO:0032880810.017
sensory perceptionGO:00076001010.017
negative regulation of protein phosphorylationGO:0001933440.017
negative regulation of catalytic activityGO:00430861030.017
central nervous system developmentGO:00074173110.017
negative regulation of neurogenesisGO:0050768780.017
guanosine containing compound catabolic processGO:1901069710.017
response to carbohydrateGO:00097431830.016
purine ribonucleoside metabolic processGO:00461281680.016
regulation of locomotionGO:00400121480.016
carbohydrate derivative biosynthetic processGO:19011371240.016
positive regulation of protein metabolic processGO:00512471780.016
positive regulation of intracellular signal transductionGO:19025331380.016
gtp metabolic processGO:0046039720.016
positive regulation of rna biosynthetic processGO:19026801970.016
multicellular organismal reproductive processGO:00486092330.016
negative regulation of cellular component organizationGO:0051129830.016
regulation of nucleotide metabolic processGO:00061401170.016
neuron developmentGO:00486662860.016
chemical homeostasisGO:00488782920.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
positive regulation of cell proliferationGO:00082842490.015
negative regulation of programmed cell deathGO:00430691830.015
head developmentGO:00603222470.015
regenerationGO:00310991630.015
asymmetric protein localizationGO:000810520.015
response to hexoseGO:00097461440.015
nucleoside triphosphate catabolic processGO:00091431230.015
response to mechanical stimulusGO:00096121340.015
immune responseGO:00069551040.015
organic hydroxy compound metabolic processGO:19016151150.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
positive regulation of signal transductionGO:00099671750.015
single organism intracellular transportGO:19025821660.015
cation transportGO:00068123820.015
positive regulation of ion transportGO:0043270940.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
female pregnancyGO:00075651220.015
anterior posterior pattern specificationGO:000995210.015
negative regulation of cell developmentGO:0010721820.015
muscle system processGO:00030121150.015
monovalent inorganic cation transportGO:00156721720.015
regulation of immune system processGO:00026821230.015
regulation of cell migrationGO:00303341280.015
cellular component biogenesisGO:00440853680.014
cytoskeleton organizationGO:00070101110.014
cation homeostasisGO:00550801950.014
regulation of hormone levelsGO:00108171870.014
response to bacteriumGO:00096172000.014
cellular response to oxidative stressGO:0034599760.014
purine ribonucleotide catabolic processGO:00091541360.014
response to radiationGO:00093141370.014
response to monosaccharideGO:00342841590.014
positive regulation of developmental processGO:00510942830.014
circulatory system processGO:00030131830.014
negative regulation of cell communicationGO:00106481580.014
Fly
negative regulation of rna biosynthetic processGO:19026791180.014
cellular component morphogenesisGO:00329891550.014
cell morphogenesis involved in differentiationGO:00009041190.014
inorganic ion transmembrane transportGO:00986602290.014
single organism behaviorGO:00447081300.014
muscle cell proliferationGO:0033002840.014
transmembrane transportGO:00550854120.014
cell cell signalingGO:00072673350.014
chromatin organizationGO:0006325340.014
protein oligomerizationGO:00512591910.014
striated muscle tissue developmentGO:0014706580.014
negative regulation of cell proliferationGO:00082851190.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
regulation of proteasomal protein catabolic processGO:006113640.013
blood circulationGO:00080151830.013
cell adhesionGO:00071551100.013
nucleoside phosphate biosynthetic processGO:19012931020.013
monosaccharide metabolic processGO:0005996610.013
glycosyl compound catabolic processGO:19016581260.013
negative regulation of neuron differentiationGO:0045665620.013
regulation of cell morphogenesisGO:0022604770.013
protein complex biogenesisGO:00702712630.013
single organism cellular localizationGO:19025801020.013
negative regulation of apoptotic processGO:00430661810.013
glycerolipid metabolic processGO:0046486670.013
negative regulation of protein modification processGO:0031400520.013
lipid storageGO:001991510.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
cell cycle checkpointGO:000007520.013
regulation of fat cell differentiationGO:004559830.013
regulation of purine nucleotide metabolic processGO:19005421150.013
cellular response to acid chemicalGO:0071229750.013
chromosome segregationGO:000705920.013
ion homeostasisGO:00508012120.013
cell growthGO:00160491040.013
cardiovascular system developmentGO:00723581340.013
single organism reproductive processGO:00447022970.013
regulation of ras protein signal transductionGO:0046578450.013
Fly
response to cytokineGO:00340972150.013
carboxylic acid biosynthetic processGO:0046394830.013
regulation of nucleocytoplasmic transportGO:0046822280.012
positive regulation of cell developmentGO:00107201760.012
single organism organelle organizationGO:19025891800.012
protein heterooligomerizationGO:0051291890.012
negative regulation of cell projection organizationGO:0031345500.012
cellular homeostasisGO:00197252520.012
response to glucoseGO:00097491360.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
negative regulation of multicellular organismal processGO:00512412030.012
mapk cascadeGO:00001651400.012
sequestering of triglycerideGO:003073010.012
cell morphogenesisGO:00009021420.012
response to estradiolGO:00323551640.012
response to glucocorticoidGO:00513842230.012
organophosphate biosynthetic processGO:00904071430.012
protein transportGO:00150311320.012
cellular response to growth factor stimulusGO:00713631620.012
cellular response to transforming growth factor beta stimulusGO:0071560410.012
regulation of ion transportGO:00432692450.012
regulation of response to woundingGO:1903034690.012
rho protein signal transductionGO:0007266110.012
regulation of canonical wnt signaling pathwayGO:006082840.012
alcohol metabolic processGO:0006066770.012
secretion by cellGO:00329402480.012
protein localization to nucleusGO:0034504390.011
regulation of establishment of protein localizationGO:0070201690.011
response to interleukin 1GO:0070555550.011
neurotrophin productionGO:003289820.011
cellular response to lipidGO:00713962010.011
positive regulation of cellular catabolic processGO:0031331710.011
purine nucleoside catabolic processGO:00061521240.011
regulation of smooth muscle cell proliferationGO:0048660750.011
response to retinoic acidGO:0032526630.011
response to molecule of bacterial originGO:00022371940.011
regulation of secretionGO:00510462240.011
muscle tissue developmentGO:0060537580.011
syncytium formationGO:000694940.011
transmission of nerve impulseGO:0019226420.011
purine ribonucleotide biosynthetic processGO:0009152810.011
negative regulation of signalingGO:00230571570.011
Fly
regulation of cell motilityGO:20001451310.011
guanosine containing compound metabolic processGO:1901068740.011
regulation of mapk cascadeGO:00434081160.011
protein maturationGO:0051604680.011
regulation of response to external stimulusGO:00321011060.011
negative regulation of response to stimulusGO:00485851550.011
Fly
myoblast fusionGO:000752020.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
jak stat cascadeGO:0007259260.011
response to other organismGO:00517072200.011
response to decreased oxygen levelsGO:00362932370.011
vesicle mediated transportGO:00161921810.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
negative regulation of cell cycle phase transitionGO:190198840.011
transforming growth factor beta receptor signaling pathwayGO:0007179180.010
morphogenesis of an epitheliumGO:0002009200.010
organic acid transportGO:00158491160.010
regulation of purine nucleotide catabolic processGO:0033121650.010
response to transforming growth factor betaGO:0071559460.010
positive regulation of cell deathGO:00109421840.010
multicellular organism growthGO:003526410.010
reactive nitrogen species metabolic processGO:200105710.010
nucleotide biosynthetic processGO:0009165980.010
defense response to gram negative bacteriumGO:005082930.010
liver developmentGO:0001889900.010
dephosphorylationGO:0016311980.010

Mknk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
myopathyDOID:42300.013
muscular diseaseDOID:008000000.013
musculoskeletal system diseaseDOID:1700.013
muscle tissue diseaseDOID:6600.013