Rattus norvegicus

45 known processes

Mknk1

MAP kinase-interacting serine/threonine kinase 1

(Aliases: MGC112775)

Mknk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to endogenous stimulusGO:00714953770.120
positive regulation of biosynthetic processGO:00098913190.086
organophosphate metabolic processGO:00196373700.069
cellular response to hormone stimulusGO:00328702470.068
macromolecule localizationGO:00330362520.068
regulation of cell proliferationGO:00421273590.066
positive regulation of multicellular organismal processGO:00512403870.065
negative regulation of metabolic processGO:00098923310.052
cell projection organizationGO:00300303020.050
cellular response to oxygen containing compoundGO:19017013860.049
neuron developmentGO:00486662860.049
regulation of cellular localizationGO:00603412630.049
secretionGO:00469033070.048
regulation of signal transductionGO:00099663180.043
Fly
organic acid metabolic processGO:00060822920.042
oxoacid metabolic processGO:00434362900.042
regulation of phosphorus metabolic processGO:00511743490.041
carbohydrate derivative metabolic processGO:19011353460.039
nucleobase containing small molecule metabolic processGO:00550863160.039
response to campGO:0051591910.039
response to organophosphorusGO:00466831020.038
carboxylic acid metabolic processGO:00197522890.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
macromolecular complex subunit organizationGO:00439333390.036
regulation of phosphorylationGO:00423252480.035
single organism catabolic processGO:00447122830.035
amine metabolic processGO:0009308380.034
positive regulation of catalytic activityGO:00430851840.034
neuron apoptotic processGO:0051402880.034
response to peptideGO:19016522920.034
cellular response to organic cyclic compoundGO:00714072020.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
single organism biosynthetic processGO:00447113420.034
regulation of cellular protein metabolic processGO:00322682670.034
protein complex subunit organizationGO:00718223020.033
multi organism reproductive processGO:00447032620.033
regulation of cellular component organizationGO:00511283680.033
cellular component assemblyGO:00226073600.033
cellular component biogenesisGO:00440853680.033
neurological system processGO:00508772190.032
positive regulation of transportGO:00510502450.032
positive regulation of cell deathGO:00109421840.032
positive regulation of nitrogen compound metabolic processGO:00511733340.032
response to oxygen levelsGO:00704822650.031
nucleotide metabolic processGO:00091172790.031
negative regulation of cellular biosynthetic processGO:00313271610.031
regulation of phosphate metabolic processGO:00192203490.031
positive regulation of cellular biosynthetic processGO:00313282950.031
response to estrogenGO:00436272320.031
cellular response to lipidGO:00713962010.031
single organism intracellular transportGO:19025821660.030
circulatory system developmentGO:00723591340.030
single organism reproductive processGO:00447022970.030
regulation of molecular functionGO:00650093980.030
cardiovascular system developmentGO:00723581340.029
cellular homeostasisGO:00197252520.029
cellular component movementGO:00069282480.029
cellular amine metabolic processGO:0044106380.029
negative regulation of cellular metabolic processGO:00313242810.029
positive regulation of phosphate metabolic processGO:00459372620.029
regulation of neuron deathGO:19012141150.028
neuron projection developmentGO:00311752730.028
nucleic acid templated transcriptionGO:00976593790.028
positive regulation of programmed cell deathGO:00430681570.028
positive regulation of rna metabolic processGO:00512542030.028
intracellular transportGO:00469071850.028
cellular catabolic processGO:00442482950.028
nucleoside phosphate metabolic processGO:00067532830.028
cellular macromolecule localizationGO:00707271220.027
organelle organizationGO:00069962660.027
cellular ketone metabolic processGO:0042180510.027
cellular protein localizationGO:00346131220.027
reproductive processGO:00224143720.027
organic substance catabolic processGO:19015753160.027
negative regulation of transportGO:00510511360.026
cellular chemical homeostasisGO:00550822470.026
response to acid chemicalGO:00011012220.026
regulation of system processGO:00440572080.026
positive regulation of phosphorylationGO:00423271770.026
neuron differentiationGO:00301823680.026
response to nutrient levelsGO:00316673700.026
catabolic processGO:00090563510.025
regulation of catalytic activityGO:00507903040.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
response to peptide hormoneGO:00434342780.025
regulation of ion transportGO:00432692450.025
mapk cascadeGO:00001651400.025
regulation of nervous system developmentGO:00519602640.025
behaviorGO:00076102050.024
response to extracellular stimulusGO:00099913800.024
metal ion homeostasisGO:00550651860.024
regulation of transcription dna templatedGO:00063553740.024
protein transportGO:00150311320.024
positive regulation of protein metabolic processGO:00512471780.024
regulation of protein metabolic processGO:00512462890.024
homeostatic processGO:00425923310.024
regulation of cellular ketone metabolic processGO:0010565270.023
reproductionGO:00000032450.023
neuron deathGO:00709971270.023
response to purine containing compoundGO:00140741260.023
intracellular signal transductionGO:00355563140.023
Human Mouse Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
cell type specific apoptotic processGO:00972851340.023
regulation of cellular amino acid metabolic processGO:000652120.023
positive regulation of apoptotic processGO:00430651540.023
organonitrogen compound biosynthetic processGO:19015661670.023
regulation of rna metabolic processGO:00512523910.022
response to decreased oxygen levelsGO:00362932370.022
locomotionGO:00400112370.022
cellular cation homeostasisGO:00300031800.022
regulation of neuron apoptotic processGO:0043523830.022
rna biosynthetic processGO:00327743800.022
positive regulation of developmental processGO:00510942830.021
g protein coupled receptor signaling pathwayGO:00071862420.021
establishment of protein localizationGO:00451841410.021
protein oligomerizationGO:00512591910.021
positive regulation of cell proliferationGO:00082842490.021
cellular amino acid metabolic processGO:00065201070.021
protein complex biogenesisGO:00702712630.021
regulation of secretionGO:00510462240.021
reactive oxygen species biosynthetic processGO:190340980.021
rna metabolic processGO:00160704060.021
protein localizationGO:00081041910.021
regulation of homeostatic processGO:00328441010.021
regulation of kinase activityGO:00435491170.021
cation homeostasisGO:00550801950.021
ribose phosphate metabolic processGO:00196932350.021
regulation of transferase activityGO:00513381230.021
regulation of rna biosynthetic processGO:20011413810.021
response to hypoxiaGO:00016662310.021
central nervous system developmentGO:00074173110.021
multicellular organism reproductionGO:00325042330.021
negative regulation of rna metabolic processGO:00512531230.020
purine ribonucleotide metabolic processGO:00091502270.020
regulation of cell differentiationGO:00455953200.020
positive regulation of molecular functionGO:00440932300.020
regulation of programmed cell deathGO:00430673410.020
ribonucleoside metabolic processGO:00091191740.020
ribonucleotide metabolic processGO:00092592310.020
multicellular organismal reproductive processGO:00486092330.020
organic acid transportGO:00158491160.020
vesicle mediated transportGO:00161921810.020
response to estradiolGO:00323551640.020
organic anion transportGO:00157111320.019
response to metal ionGO:00100382530.019
cellular response to nitrogen compoundGO:19016992100.019
regulation of cellular amine metabolic processGO:003323880.019
chemical homeostasisGO:00488782920.019
tissue developmentGO:00098882520.019
protein phosphorylationGO:00064683450.019
fatty acid metabolic processGO:0006631990.019
ion homeostasisGO:00508012120.019
positive regulation of transcription dna templatedGO:00458931970.018
response to mechanical stimulusGO:00096121340.018
purine containing compound metabolic processGO:00725212530.018
response to nutrientGO:00075842480.018
anatomical structure morphogenesisGO:00096532980.018
carbohydrate metabolic processGO:00059751300.018
positive regulation of protein modification processGO:00314011420.018
regulation of mapk cascadeGO:00434081160.018
cell cell signalingGO:00072673350.018
negative regulation of biosynthetic processGO:00098901680.018
cellular metal ion homeostasisGO:00068751720.018
regulation of protein kinase activityGO:00458591050.017
positive regulation of cellular protein metabolic processGO:00322701670.017
heterocycle catabolic processGO:00467001670.017
glycosyl compound metabolic processGO:19016571820.017
carboxylic acid transportGO:00469421150.017
divalent inorganic cation homeostasisGO:00725071650.017
protein complex assemblyGO:00064612630.017
positive regulation of cellular amine metabolic processGO:003324030.017
negative regulation of gene expressionGO:00106291990.017
regulation of neurogenesisGO:00507672470.017
positive regulation of phosphorus metabolic processGO:00105622620.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
axis specificationGO:000979840.017
response to inorganic substanceGO:00100353770.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
aromatic compound catabolic processGO:00194391680.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
response to monosaccharideGO:00342841590.016
metal ion transportGO:00300012890.016
cellular response to stressGO:00335542690.016
regulation of protein modification processGO:00313991940.016
regulation of cell developmentGO:00602842630.016
regulation of cell motilityGO:20001451310.016
anion transportGO:00068201780.016
response to temperature stimulusGO:0009266940.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
cation transportGO:00068123820.016
cellular lipid metabolic processGO:00442552080.016
regulation of membrane potentialGO:00423911100.016
brain developmentGO:00074202470.016
angiogenesisGO:0001525530.016
negative regulation of macromolecule metabolic processGO:00106052600.016
positive regulation of gene expressionGO:00106282440.016
purine ribonucleoside metabolic processGO:00461281680.016
oxidation reduction processGO:00551143040.016
regulation of anatomical structure morphogenesisGO:00226031410.016
nucleotide catabolic processGO:00091661390.016
transcription from rna polymerase ii promoterGO:00063662520.016
reactive oxygen species metabolic processGO:0072593370.016
response to carbohydrateGO:00097431830.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
regulation of hormone levelsGO:00108171870.015
purine nucleotide metabolic processGO:00061632290.015
nitrogen compound transportGO:00717052290.015
cellular nitrogen compound catabolic processGO:00442701630.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
positive regulation of cell motilityGO:2000147970.015
negative regulation of cell communicationGO:00106481580.015
Fly
positive regulation of cellular component organizationGO:00511302000.015
positive regulation of endothelial cell migrationGO:001059540.015
organic acid biosynthetic processGO:0016053830.015
multicellular organism growthGO:003526410.015
regulation of intracellular signal transductionGO:19025312180.015
Fly
synaptic transmissionGO:00072682350.015
response to ethanolGO:00454711620.015
transmembrane transportGO:00550854120.015
cellular response to organonitrogen compoundGO:00714171970.015
positive regulation of neuron deathGO:1901216430.015
response to hexoseGO:00097461440.015
proteolysisGO:00065081750.015
blood vessel developmentGO:0001568690.014
response to oxidative stressGO:00069791860.014
calcium ion homeostasisGO:00550741620.014
transcription dna templatedGO:00063513770.014
negative regulation of phosphate metabolic processGO:0045936800.014
organophosphate biosynthetic processGO:00904071430.014
organonitrogen compound catabolic processGO:19015651790.014
nucleoside metabolic processGO:00091161790.014
cellular ion homeostasisGO:00068731840.014
carbohydrate derivative biosynthetic processGO:19011371240.014
positive regulation of rna biosynthetic processGO:19026801970.014
nucleobase containing compound catabolic processGO:00346551520.014
protein heterooligomerizationGO:0051291890.014
lipid metabolic processGO:00066292830.014
cellular response to peptideGO:19016531330.014
response to growth factorGO:00708481890.014
carboxylic acid biosynthetic processGO:0046394830.014
positive regulation of mapk cascadeGO:0043410920.014
localization of cellGO:00516742020.014
female pregnancyGO:00075651220.014
taxisGO:0042330670.013
muscle system processGO:00030121150.013
cellular response to cytokine stimulusGO:00713451270.013
negative regulation of multicellular organismal processGO:00512412030.013
multi multicellular organism processGO:00447061380.013
regulation of apoptotic processGO:00429813350.013
secretion by cellGO:00329402480.013
positive regulation of protein phosphorylationGO:00019341350.013
signal releaseGO:00230611450.013
negative regulation of phosphorus metabolic processGO:0010563800.013
negative regulation of signalingGO:00230571570.013
Fly
neuron projection morphogenesisGO:00488121220.013
organophosphate catabolic processGO:00464341480.013
positive regulation of cell projection organizationGO:00313461110.013
cellular response to peptide hormone stimulusGO:00713751200.013
regulation of nucleotide metabolic processGO:00061401170.013
regulation of protein localizationGO:0032880810.013
regulation of protein phosphorylationGO:00019321830.013
macromolecular complex assemblyGO:00650032730.013
positive regulation of locomotionGO:00400171020.013
activation of protein kinase activityGO:0032147470.013
response to transition metal nanoparticleGO:19902671220.013
response to glucoseGO:00097491360.013
actin filament based processGO:0030029860.013
positive regulation of kinase activityGO:0033674770.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
membrane tubulationGO:009732020.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
multicellular organismal signalingGO:0035637440.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
cellular response to alcoholGO:0097306870.012
vasculature developmentGO:0001944700.012
purine nucleotide catabolic processGO:00061951360.012
regulation of cellular component biogenesisGO:0044087860.012
response to cytokineGO:00340972150.012
cytoplasmic transportGO:00164821150.012
apoptotic processGO:00069153810.012
Mouse
cytokinetic processGO:003250610.012
vascular process in circulatory systemGO:0003018960.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
insulin like growth factor receptor signaling pathwayGO:004800930.012
positive regulation of cell developmentGO:00107201760.012
regulation of vesicle mediated transportGO:0060627810.012
ion transmembrane transportGO:00342203650.012
endocytosisGO:0006897840.012
smooth muscle cell migrationGO:0014909360.012
positive regulation of nervous system developmentGO:00519621780.012
membrane organizationGO:0061024940.012
reproductive structure developmentGO:00486081280.012
regulation of establishment of protein localizationGO:0070201690.012
small gtpase mediated signal transductionGO:0007264360.012
Fly
blood circulationGO:00080151830.012
response to vitaminGO:00332731310.012
negative regulation of cell deathGO:00605482290.011
cell migrationGO:00164771970.011
positive regulation of signalingGO:00230562700.011
antigen receptor mediated signaling pathwayGO:005085110.011
cellular response to lipopolysaccharideGO:0071222550.011
cellular component morphogenesisGO:00329891550.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
cytoskeleton dependent cytokinesisGO:006164020.011
regulation of tube sizeGO:0035150890.011
head developmentGO:00603222470.011
reactive nitrogen species metabolic processGO:200105710.011
positive regulation of protein kinase activityGO:0045860730.011
cellular response to external stimulusGO:00714961180.011
growthGO:00400071650.011
Fly
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of cell migrationGO:0030335960.011
purine nucleoside metabolic processGO:00422781690.011
jnk cascadeGO:0007254280.011
response to retinoic acidGO:0032526630.011
response to external biotic stimulusGO:00432072210.011
positive regulation of secretionGO:00510471400.011
negative regulation of protein metabolic processGO:00512481140.011
neuronal action potentialGO:0019228350.011
monocarboxylic acid metabolic processGO:00327871520.011
regulation of neuron differentiationGO:00456642080.011
regulation of cell migrationGO:00303341280.011
response to radiationGO:00093141370.011
regulation of fat cell differentiationGO:004559830.011
regulation of blood vessel sizeGO:0050880890.011
regulation of lipid metabolic processGO:0019216680.011
negative regulation of developmental processGO:00510931250.011
single organism organelle organizationGO:19025891800.011
positive regulation of neuron differentiationGO:00456661260.011
action potentialGO:0001508540.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
defense responseGO:00069521940.011
cell projection morphogenesisGO:00488581230.011
signal transduction by phosphorylationGO:00230141440.010
sexual reproductionGO:00199531480.010
regulation of cellular component movementGO:00512701500.010
cell cycleGO:00070491010.010
response to woundingGO:00096112540.010
cellular carbohydrate metabolic processGO:0044262720.010
positive regulation of neurogenesisGO:00507691650.010
negative regulation of cell proliferationGO:00082851190.010
blood vessel morphogenesisGO:0048514580.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
lipid storageGO:001991510.010
appendage morphogenesisGO:003510740.010
cytosolic calcium ion homeostasisGO:00514801400.010
positive regulation of cellular component movementGO:00512721020.010
programmed cell deathGO:00125013920.010
Mouse
nucleoside phosphate catabolic processGO:19012921400.010
positive regulation of neuron apoptotic processGO:0043525330.010
nucleoside phosphate biosynthetic processGO:19012931020.010
lipid biosynthetic processGO:00086101280.010

Mknk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
musculoskeletal system diseaseDOID:1700.015
disease of cellular proliferationDOID:1456600.012
sensory system diseaseDOID:005015500.012
central nervous system diseaseDOID:33100.011