Rattus norvegicus

0 known processes

Lrrc8a

leucine rich repeat containing 8 family, member A

(Aliases: Lrrc8)

Lrrc8a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle organizationGO:00069962660.097
cellular component assemblyGO:00226073600.091
rna metabolic processGO:00160704060.089
regulation of cellular component organizationGO:00511283680.087
rna biosynthetic processGO:00327743800.085
regulation of molecular functionGO:00650093980.078
cellular component biogenesisGO:00440853680.076
neuron projection developmentGO:00311752730.074
carboxylic acid metabolic processGO:00197522890.073
oxoacid metabolic processGO:00434362900.072
positive regulation of nitrogen compound metabolic processGO:00511733340.070
cell projection organizationGO:00300303020.066
transcription dna templatedGO:00063513770.065
negative regulation of metabolic processGO:00098923310.062
nucleic acid templated transcriptionGO:00976593790.062
intracellular signal transductionGO:00355563140.060
cellular response to endogenous stimulusGO:00714953770.060
regulation of nervous system developmentGO:00519602640.060
organic acid metabolic processGO:00060822920.060
regulation of cell proliferationGO:00421273590.059
transmembrane transportGO:00550854120.059
Human
response to inorganic substanceGO:00100353770.058
regulation of multicellular organismal developmentGO:20000263760.058
cellular response to oxygen containing compoundGO:19017013860.057
regulation of rna metabolic processGO:00512523910.056
regulation of cell differentiationGO:00455953200.055
anatomical structure morphogenesisGO:00096532980.055
ion transmembrane transportGO:00342203650.055
Human
negative regulation of cellular metabolic processGO:00313242810.055
positive regulation of biosynthetic processGO:00098913190.055
positive regulation of transportGO:00510502450.055
positive regulation of nucleobase containing compound metabolic processGO:00459353190.054
regulation of rna biosynthetic processGO:20011413810.054
cellular amino acid metabolic processGO:00065201070.054
cellular chemical homeostasisGO:00550822470.053
regulation of transcription dna templatedGO:00063553740.053
homeostatic processGO:00425923310.052
Human
response to peptideGO:19016522920.052
central nervous system developmentGO:00074173110.052
regulation of phosphate metabolic processGO:00192203490.051
neuron differentiationGO:00301823680.050
single organism biosynthetic processGO:00447113420.050
cellular component movementGO:00069282480.049
positive regulation of cellular component organizationGO:00511302000.048
positive regulation of multicellular organismal processGO:00512403870.048
regulation of nucleic acid templated transcriptionGO:19035063800.047
neuron developmentGO:00486662860.047
regulation of cellular localizationGO:00603412630.047
positive regulation of cellular biosynthetic processGO:00313282950.047
cellular response to nitrogen compoundGO:19016992100.046
regulation of neurogenesisGO:00507672470.046
positive regulation of response to stimulusGO:00485842850.046
cellular response to hormone stimulusGO:00328702470.046
positive regulation of molecular functionGO:00440932300.046
response to estrogenGO:00436272320.045
single organism organelle organizationGO:19025891800.045
head developmentGO:00603222470.044
transcription from rna polymerase ii promoterGO:00063662520.043
chemical homeostasisGO:00488782920.043
positive regulation of macromolecule biosynthetic processGO:00105572470.043
inorganic cation transmembrane transportGO:00986622020.043
macromolecular complex assemblyGO:00650032730.042
positive regulation of cell communicationGO:00106472710.042
response to extracellular stimulusGO:00099913800.042
apoptotic processGO:00069153810.042
macromolecular complex subunit organizationGO:00439333390.042
cellular homeostasisGO:00197252520.042
Human
positive regulation of transcription dna templatedGO:00458931970.042
cellular catabolic processGO:00442482950.042
regulation of cell developmentGO:00602842630.042
regulation of catalytic activityGO:00507903040.042
regulation of cellular protein metabolic processGO:00322682670.041
regulation of programmed cell deathGO:00430673410.040
cellular response to peptide hormone stimulusGO:00713751200.040
positive regulation of gene expressionGO:00106282440.040
positive regulation of signalingGO:00230562700.039
catabolic processGO:00090563510.039
response to peptide hormoneGO:00434342780.039
protein phosphorylationGO:00064683450.039
negative regulation of multicellular organismal processGO:00512412030.039
cellular amine metabolic processGO:0044106380.039
reproductive processGO:00224143720.039
organic substance catabolic processGO:19015753160.038
cellular component morphogenesisGO:00329891550.038
regulation of cellular component movementGO:00512701500.038
protein complex subunit organizationGO:00718223020.038
negative regulation of macromolecule metabolic processGO:00106052600.037
regulation of signal transductionGO:00099663180.037
anion transportGO:00068201780.037
Human
regulation of ion transportGO:00432692450.037
regulation of phosphorylationGO:00423252480.037
vesicle mediated transportGO:00161921810.037
negative regulation of nitrogen compound metabolic processGO:00511721610.037
positive regulation of cell differentiationGO:00455972170.036
organophosphate metabolic processGO:00196373700.036
cation transportGO:00068123820.036
cellular ketone metabolic processGO:0042180510.036
localization of cellGO:00516742020.036
nitrogen compound transportGO:00717052290.036
intracellular transportGO:00469071850.036
regulation of protein metabolic processGO:00512462890.036
metal ion transportGO:00300012890.036
response to nutrient levelsGO:00316673700.036
response to corticosteroidGO:00319602350.036
cellular cation homeostasisGO:00300031800.035
carbohydrate derivative metabolic processGO:19011353460.035
positive regulation of phosphorus metabolic processGO:00105622620.035
secretion by cellGO:00329402480.035
programmed cell deathGO:00125013920.035
amine metabolic processGO:0009308380.034
regulation of secretionGO:00510462240.034
inorganic ion transmembrane transportGO:00986602290.034
positive regulation of catalytic activityGO:00430851840.034
cellular metal ion homeostasisGO:00068751720.034
positive regulation of developmental processGO:00510942830.033
negative regulation of biosynthetic processGO:00098901680.033
regulation of neuron projection developmentGO:00109751610.033
secretionGO:00469033070.033
cellular response to organic cyclic compoundGO:00714072020.033
circulatory system processGO:00030131830.033
response to metal ionGO:00100382530.033
cellular response to peptideGO:19016531330.033
multi organism reproductive processGO:00447032620.033
cellular ion homeostasisGO:00068731840.032
cation homeostasisGO:00550801950.032
regulation of phosphorus metabolic processGO:00511743490.032
response to woundingGO:00096112540.032
single organism reproductive processGO:00447022970.032
ion homeostasisGO:00508012120.032
positive regulation of rna metabolic processGO:00512542030.031
growthGO:00400071650.031
positive regulation of rna biosynthetic processGO:19026801970.031
regulation of cellular ketone metabolic processGO:0010565270.031
positive regulation of cell proliferationGO:00082842490.031
neuron projection morphogenesisGO:00488121220.031
lipid metabolic processGO:00066292830.031
regulation of locomotionGO:00400121480.031
positive regulation of cellular protein metabolic processGO:00322701670.031
gland developmentGO:00487321550.030
metal ion homeostasisGO:00550651860.030
multicellular organism reproductionGO:00325042330.030
cellular response to organonitrogen compoundGO:00714171970.030
regulation of system processGO:00440572080.030
regulation of cellular amine metabolic processGO:003323880.030
cation transmembrane transportGO:00986552630.030
cell part morphogenesisGO:00329901230.030
negative regulation of signalingGO:00230571570.030
response to nutrientGO:00075842480.030
regulation of neuron differentiationGO:00456642080.030
response to glucocorticoidGO:00513842230.030
cellular divalent inorganic cation homeostasisGO:00725031620.030
macromolecule localizationGO:00330362520.030
cellular response to stressGO:00335542690.029
positive regulation of nucleic acid templated transcriptionGO:19035081970.029
divalent inorganic cation homeostasisGO:00725071650.029
regulation of cell projection organizationGO:00313441750.029
negative regulation of cellular biosynthetic processGO:00313271610.029
cell projection morphogenesisGO:00488581230.029
protein complex biogenesisGO:00702712630.029
tissue developmentGO:00098882520.029
lipid biosynthetic processGO:00086101280.029
cell cell signalingGO:00072673350.028
response to carbohydrateGO:00097431830.028
nucleotide metabolic processGO:00091172790.028
negative regulation of gene expressionGO:00106291990.028
rhythmic processGO:00485111560.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
negative regulation of response to stimulusGO:00485851550.028
positive regulation of phosphate metabolic processGO:00459372620.028
cell motilityGO:00488702020.028
g protein coupled receptor signaling pathwayGO:00071862420.027
response to insulinGO:00328681330.027
regulation of protein phosphorylationGO:00019321830.027
positive regulation of protein metabolic processGO:00512471780.027
regulation of protein modification processGO:00313991940.027
regulation of intracellular signal transductionGO:19025312180.027
cell growthGO:00160491040.027
reproductionGO:00000032450.026
cell morphogenesisGO:00009021420.026
negative regulation of phosphate metabolic processGO:0045936800.026
positive regulation of nervous system developmentGO:00519621780.026
regulation of cellular amino acid metabolic processGO:000652120.026
cellular calcium ion homeostasisGO:00068741600.026
response to acid chemicalGO:00011012220.026
multicellular organismal reproductive processGO:00486092330.026
single organism catabolic processGO:00447122830.026
calcium ion homeostasisGO:00550741620.026
positive regulation of signal transductionGO:00099671750.025
cytosolic calcium ion homeostasisGO:00514801400.025
membrane organizationGO:0061024940.025
regulation of apoptotic processGO:00429813350.025
protein complex assemblyGO:00064612630.025
purine containing compound metabolic processGO:00725212530.025
brain developmentGO:00074202470.025
nucleoside phosphate metabolic processGO:00067532830.025
response to growth factorGO:00708481890.025
blood circulationGO:00080151830.025
tube developmentGO:0035295890.025
regulation of metal ion transportGO:00109591180.025
organophosphate biosynthetic processGO:00904071430.024
defense responseGO:00069521940.024
proteolysisGO:00065081750.024
cellular lipid metabolic processGO:00442552080.024
heart morphogenesisGO:000300730.024
multicellular organismal signalingGO:0035637440.024
positive regulation of cell developmentGO:00107201760.024
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.024
negative regulation of neurogenesisGO:0050768780.023
negative regulation of developmental processGO:00510931250.023
cell morphogenesis involved in differentiationGO:00009041190.023
synaptic growth at neuromuscular junctionGO:005112410.023
nucleobase containing small molecule metabolic processGO:00550863160.023
regulation of membrane potentialGO:00423911100.023
locomotionGO:00400112370.023
organonitrogen compound catabolic processGO:19015651790.023
response to oxidative stressGO:00069791860.022
protein localizationGO:00081041910.022
cellular response to growth factor stimulusGO:00713631620.022
response to hypoxiaGO:00016662310.022
ras protein signal transductionGO:0007265290.022
response to estradiolGO:00323551640.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
neurological system processGO:00508772190.022
regulation of hormone levelsGO:00108171870.022
actin filament based processGO:0030029860.022
response to oxygen levelsGO:00704822650.022
positive regulation of phosphorylationGO:00423271770.021
organophosphate catabolic processGO:00464341480.021
response to hexoseGO:00097461440.021
response to decreased oxygen levelsGO:00362932370.021
positive regulation of ion transportGO:0043270940.021
behaviorGO:00076102050.021
negative regulation of phosphorus metabolic processGO:0010563800.021
epithelium developmentGO:0060429960.021
carbohydrate metabolic processGO:00059751300.021
negative regulation of cellular component organizationGO:0051129830.021
cell migrationGO:00164771970.021
regulation of secretion by cellGO:19035302080.021
regulation of immune system processGO:00026821230.021
response to ethanolGO:00454711620.020
cellular protein localizationGO:00346131220.020
single organism intracellular transportGO:19025821660.020
anion transmembrane transportGO:0098656770.020
carboxylic acid transportGO:00469421150.020
ribonucleotide metabolic processGO:00092592310.020
positive regulation of cytosolic calcium ion concentrationGO:00072041220.020
purine ribonucleotide metabolic processGO:00091502270.020
negative regulation of nervous system developmentGO:0051961790.020
negative regulation of cell communicationGO:00106481580.020
cell morphogenesis involved in neuron differentiationGO:00486671060.020
regulation of growthGO:00400081050.020
regulation of cell motilityGO:20001451310.020
single organism carbohydrate metabolic processGO:00447231180.020
negative regulation of rna biosynthetic processGO:19026791180.019
forebrain developmentGO:0030900980.019
negative regulation of rna metabolic processGO:00512531230.019
synaptic transmissionGO:00072682350.019
peptidyl amino acid modificationGO:00181931260.019
single organism membrane organizationGO:0044802740.019
dephosphorylationGO:0016311980.019
organonitrogen compound biosynthetic processGO:19015661670.019
response to monosaccharideGO:00342841590.019
ribose phosphate metabolic processGO:00196932350.019
negative regulation of transportGO:00510511360.019
cellular response to lipidGO:00713962010.019
epithelial cell differentiationGO:0030855710.019
positive regulation of protein modification processGO:00314011420.019
purine nucleotide metabolic processGO:00061632290.019
wound healingGO:00420601220.019
regulation of ion transmembrane transportGO:00347651210.019
regulation of cell growthGO:0001558850.019
response to glucoseGO:00097491360.019
regulation of vesicle mediated transportGO:0060627810.019
regulation of anatomical structure morphogenesisGO:00226031410.019
anterior posterior pattern specificationGO:000995210.019
positive regulation of cell projection organizationGO:00313461110.018
organic acid transportGO:00158491160.018
small molecule biosynthetic processGO:00442831240.018
negative regulation of cell developmentGO:0010721820.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
cellular response to insulin stimulusGO:0032869810.018
regenerationGO:00310991630.018
immune system processGO:00023762040.018
Mouse
carbohydrate derivative catabolic processGO:19011361470.018
organic anion transportGO:00157111320.018
negative regulation of cell differentiationGO:0045596990.018
small gtpase mediated signal transductionGO:0007264360.018
action potentialGO:0001508540.018
negative regulation of transcription dna templatedGO:00458921160.018
oxidation reduction processGO:00551143040.018
divalent inorganic cation transportGO:00725111340.018
regulation of cell migrationGO:00303341280.018
divalent metal ion transportGO:00708381320.018
regulation of transferase activityGO:00513381230.018
calcium ion transportGO:00068161310.018
hormone transportGO:00099141210.018
single organism cellular localizationGO:19025801020.018
muscle contractionGO:0006936880.017
circadian rhythmGO:0007623880.017
developmental process involved in reproductionGO:00030061590.017
single organism behaviorGO:00447081300.017
positive regulation of cellular amine metabolic processGO:003324030.017
regulation of hydrolase activityGO:00513361430.017
regulation of transmembrane transportGO:00347621220.017
ribonucleoside metabolic processGO:00091191740.017
regulation of neuron deathGO:19012141150.017
regulation of homeostatic processGO:00328441010.017
cellular carbohydrate metabolic processGO:0044262720.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
protein oligomerizationGO:00512591910.017
positive regulation of secretion by cellGO:19035321280.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
purine ribonucleoside metabolic processGO:00461281680.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
negative regulation of cellular protein metabolic processGO:00322691060.017
epithelial cell proliferationGO:0050673540.017
cell adhesionGO:00071551100.017
glycosyl compound metabolic processGO:19016571820.017
sensory organ developmentGO:0007423740.017
positive regulation of secretionGO:00510471400.017
positive regulation of neurogenesisGO:00507691650.017
signal transduction by phosphorylationGO:00230141440.016
cellular response to alcoholGO:0097306870.016
gamete generationGO:00072761240.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
establishment of tissue polarityGO:000716420.016
axon developmentGO:0061564960.016
positive regulation of cell deathGO:00109421840.016
immune responseGO:00069551040.016
cytoskeleton organizationGO:00070101110.016
positive regulation of neuron differentiationGO:00456661260.016
salivary gland morphogenesisGO:000743510.016
positive regulation of intracellular signal transductionGO:19025331380.016
muscle system processGO:00030121150.016
circulatory system developmentGO:00723591340.016
positive regulation of protein phosphorylationGO:00019341350.016
regulation of cellular catabolic processGO:00313291010.016
biological adhesionGO:00226101100.016
purine nucleoside metabolic processGO:00422781690.016
cell type specific apoptotic processGO:00972851340.016
regulation of establishment of planar polarityGO:009017520.016
nucleoside metabolic processGO:00091161790.016
positive regulation of neuron projection developmentGO:0010976990.015
glycosyl compound catabolic processGO:19016581260.015
negative regulation of molecular functionGO:00440921330.015
salivary gland developmentGO:000743130.015
response to transition metal nanoparticleGO:19902671220.015
negative regulation of protein metabolic processGO:00512481140.015
regulation of synaptic transmissionGO:00508041410.015
response to external biotic stimulusGO:00432072210.015
negative regulation of cell proliferationGO:00082851190.015
response to cytokineGO:00340972150.015
response to ketoneGO:19016541820.015
positive regulation of apoptotic processGO:00430651540.015
hepaticobiliary system developmentGO:0061008900.015
response to purine containing compoundGO:00140741260.015
regulation of anatomical structure sizeGO:00900661350.015
actin cytoskeleton organizationGO:0030036730.015
axis specificationGO:000979840.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
organic acid biosynthetic processGO:0016053830.015
positive regulation of programmed cell deathGO:00430681570.015
response to campGO:0051591910.015
amide transportGO:00428861050.015
purine nucleoside catabolic processGO:00061521240.015
gastrulationGO:000736920.015
glycerolipid metabolic processGO:0046486670.014
protein autophosphorylationGO:0046777660.014
cellular macromolecule localizationGO:00707271220.014
positive regulation of immune system processGO:0002684900.014
purine ribonucleoside catabolic processGO:00461301240.014
female pregnancyGO:00075651220.014
heterocycle catabolic processGO:00467001670.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
eye morphogenesisGO:004859240.014
neuron deathGO:00709971270.014
negative regulation of programmed cell deathGO:00430691830.014
liver developmentGO:0001889900.014
protein transportGO:00150311320.014
sexual reproductionGO:00199531480.014
regulation of proteasomal protein catabolic processGO:006113640.014
chromosome segregationGO:000705920.014
regulation of kinase activityGO:00435491170.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
organic hydroxy compound metabolic processGO:19016151150.014
developmental growthGO:00485891000.014
phospholipid metabolic processGO:0006644610.014
regulation of blood pressureGO:0008217830.014
organic cyclic compound catabolic processGO:19013611750.014
hormone secretionGO:00468791150.014
cellular nitrogen compound catabolic processGO:00442701630.013
leukocyte activationGO:0045321760.013
Mouse
monovalent inorganic cation transportGO:00156721720.013
regulation of response to stressGO:00801341260.013
neuronal action potentialGO:0019228350.013
regulation of calcium ion transportGO:0051924770.013
nucleoside phosphate catabolic processGO:19012921400.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
response to other organismGO:00517072200.013
regulation of body fluid levelsGO:0050878900.013
muscle structure developmentGO:0061061870.013
purine containing compound catabolic processGO:00725231380.013
mapk cascadeGO:00001651400.013
endocytosisGO:0006897840.013
cell activationGO:0001775970.013
Mouse
response to biotic stimulusGO:00096072260.013
organ morphogenesisGO:0009887750.013
establishment of protein localizationGO:00451841410.013
cytoplasmic transportGO:00164821150.013
transmission of nerve impulseGO:0019226420.013
response to alkaloidGO:00432791320.013
reproductive structure developmentGO:00486081280.013
carbohydrate derivative biosynthetic processGO:19011371240.013
embryonic pattern specificationGO:000988010.013
nucleoside triphosphate metabolic processGO:00091411440.013
negative regulation of apoptotic processGO:00430661810.013
regulation of organelle organizationGO:0033043800.013
ribonucleoside catabolic processGO:00424541260.013
nucleoside triphosphate catabolic processGO:00091431230.013
response to radiationGO:00093141370.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
carboxylic acid biosynthetic processGO:0046394830.013
multicellular organism growthGO:003526410.013
spermatogenesisGO:0007283990.013
cellular response to steroid hormone stimulusGO:0071383930.013
agingGO:00075682410.012
cell cycleGO:00070491010.012
negative regulation of cell deathGO:00605482290.012
aromatic compound catabolic processGO:00194391680.012
regulation of catabolic processGO:00098941130.012
positive regulation of cellular component movementGO:00512721020.012
signal releaseGO:00230611450.012
purine ribonucleotide catabolic processGO:00091541360.012
chemotaxisGO:0006935660.012
cellular response to abiotic stimulusGO:0071214850.012
nucleobase containing compound catabolic processGO:00346551520.012
response to toxic substanceGO:00096361330.012
regulation of transporter activityGO:0032409500.012
inflammatory responseGO:00069541500.012
sulfur compound metabolic processGO:0006790700.012
nucleotide catabolic processGO:00091661390.012
regulation of response to external stimulusGO:00321011060.012
multi multicellular organism processGO:00447061380.012
ribonucleotide catabolic processGO:00092611360.012
regulation of canonical wnt signaling pathwayGO:006082840.012
eye developmentGO:0001654500.012
neural crest cell migrationGO:000175510.012
response to bacteriumGO:00096172000.012
cardiovascular system developmentGO:00723581340.012
negative regulation of neuron differentiationGO:0045665620.012
learning or memoryGO:0007611900.012
response to lipopolysaccharideGO:00324961910.011
cellular response to external stimulusGO:00714961180.011
urogenital system developmentGO:0001655780.011
morphogenesis of a polarized epitheliumGO:000173810.011
positive regulation of locomotionGO:00400171020.011
nucleoside catabolic processGO:00091641260.011
axonogenesisGO:0007409710.011
regulation of protein kinase activityGO:00458591050.011
negative regulation of catalytic activityGO:00430861030.011
purine nucleotide catabolic processGO:00061951360.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
wnt signaling pathway planar cell polarity pathwayGO:006007120.011
regulation of hormone secretionGO:00468831060.011
regulation of protein localizationGO:0032880810.011
regulation of tube sizeGO:0035150890.011
regulation of blood circulationGO:19035221100.011
male gamete generationGO:0048232990.011
taxisGO:0042330670.011
neural crest cell developmentGO:001403220.011
reproductive system developmentGO:00614581280.011
development of primary sexual characteristicsGO:00451371070.011
regulation of cell morphogenesisGO:0022604770.011
ribose phosphate biosynthetic processGO:0046390870.011
dna metabolic processGO:0006259960.011
positive regulation of cell motilityGO:2000147970.011
endomembrane system organizationGO:0010256480.011
response to mechanical stimulusGO:00096121340.011
response to molecule of bacterial originGO:00022371940.011
intracellular protein transportGO:0006886790.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
nucleoside phosphate biosynthetic processGO:19012931020.011
peptide transportGO:0015833970.011
sex differentiationGO:00075481130.011
cytoskeleton dependent cytokinesisGO:006164020.011
regulation of muscle system processGO:0090257790.010
cell cycle checkpointGO:000007520.010

Lrrc8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
Human
nervous system diseaseDOID:86300.030
musculoskeletal system diseaseDOID:1700.022
muscular diseaseDOID:008000000.014
disease of metabolismDOID:001466700.014
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011