Rattus norvegicus

0 known processes

Lrrc8b

leucine rich repeat containing 8 family, member B

(Aliases: RGD1563429)

Lrrc8b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna metabolic processGO:00512523910.082
positive regulation of multicellular organismal processGO:00512403870.082
rna biosynthetic processGO:00327743800.081
macromolecular complex subunit organizationGO:00439333390.073
neuron differentiationGO:00301823680.071
neuron developmentGO:00486662860.066
single organism biosynthetic processGO:00447113420.066
anatomical structure morphogenesisGO:00096532980.066
positive regulation of biosynthetic processGO:00098913190.064
regulation of programmed cell deathGO:00430673410.060
transcription dna templatedGO:00063513770.059
regulation of multicellular organismal developmentGO:20000263760.057
regulation of rna biosynthetic processGO:20011413810.057
catabolic processGO:00090563510.056
positive regulation of cellular biosynthetic processGO:00313282950.054
positive regulation of developmental processGO:00510942830.051
programmed cell deathGO:00125013920.051
cellular ketone metabolic processGO:0042180510.050
cellular component assemblyGO:00226073600.049
regulation of signal transductionGO:00099663180.048
oxoacid metabolic processGO:00434362900.048
organic substance catabolic processGO:19015753160.048
homeostatic processGO:00425923310.047
nucleic acid templated transcriptionGO:00976593790.047
negative regulation of metabolic processGO:00098923310.046
neuron projection developmentGO:00311752730.045
cellular response to endogenous stimulusGO:00714953770.045
regulation of nucleic acid templated transcriptionGO:19035063800.044
transmembrane transportGO:00550854120.044
cell cell signalingGO:00072673350.043
neuron projection morphogenesisGO:00488121220.043
regulation of transcription dna templatedGO:00063553740.042
lipid metabolic processGO:00066292830.042
protein complex biogenesisGO:00702712630.041
chemical homeostasisGO:00488782920.041
response to oxygen levelsGO:00704822650.041
tissue developmentGO:00098882520.040
response to decreased oxygen levelsGO:00362932370.040
cellular response to oxygen containing compoundGO:19017013860.040
negative regulation of biosynthetic processGO:00098901680.040
positive regulation of nitrogen compound metabolic processGO:00511733340.039
apoptotic processGO:00069153810.039
cellular component movementGO:00069282480.039
negative regulation of signalingGO:00230571570.038
rhythmic processGO:00485111560.038
protein complex subunit organizationGO:00718223020.038
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
regulation of cell proliferationGO:00421273590.037
transcription from rna polymerase ii promoterGO:00063662520.036
cell morphogenesis involved in differentiationGO:00009041190.036
response to inorganic substanceGO:00100353770.036
macromolecular complex assemblyGO:00650032730.035
cell projection organizationGO:00300303020.035
negative regulation of cellular metabolic processGO:00313242810.035
positive regulation of cell proliferationGO:00082842490.035
protein complex assemblyGO:00064612630.035
carbohydrate derivative metabolic processGO:19011353460.034
response to hypoxiaGO:00016662310.034
regulation of cellular ketone metabolic processGO:0010565270.034
organic acid metabolic processGO:00060822920.034
protein phosphorylationGO:00064683450.034
response to extracellular stimulusGO:00099913800.033
carboxylic acid metabolic processGO:00197522890.033
locomotionGO:00400112370.032
behaviorGO:00076102050.032
neurological system processGO:00508772190.032
regulation of apoptotic processGO:00429813350.031
single organism catabolic processGO:00447122830.031
reproductive processGO:00224143720.031
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
positive regulation of response to stimulusGO:00485842850.030
macromolecule localizationGO:00330362520.030
organonitrogen compound biosynthetic processGO:19015661670.030
cellular catabolic processGO:00442482950.029
agingGO:00075682410.028
regulation of molecular functionGO:00650093980.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
positive regulation of rna biosynthetic processGO:19026801970.028
cellular response to hormone stimulusGO:00328702470.028
regulation of cellular amino acid metabolic processGO:000652120.028
ion transmembrane transportGO:00342203650.028
metal ion transportGO:00300012890.028
negative regulation of macromolecule metabolic processGO:00106052600.027
cellular component biogenesisGO:00440853680.027
cation transportGO:00068123820.027
single organism behaviorGO:00447081300.027
response to nutrient levelsGO:00316673700.026
organophosphate metabolic processGO:00196373700.026
organelle organizationGO:00069962660.026
cellular amine metabolic processGO:0044106380.026
negative regulation of cell communicationGO:00106481580.026
cellular response to alcoholGO:0097306870.025
lipid biosynthetic processGO:00086101280.025
response to growth factorGO:00708481890.025
central nervous system developmentGO:00074173110.025
response to estrogenGO:00436272320.025
biological adhesionGO:00226101100.024
rna metabolic processGO:00160704060.024
axon developmentGO:0061564960.024
intracellular signal transductionGO:00355563140.024
regulation of phosphate metabolic processGO:00192203490.023
cell migrationGO:00164771970.023
synaptic transmissionGO:00072682350.023
regulation of cellular component organizationGO:00511283680.023
reproductionGO:00000032450.023
nucleoside phosphate metabolic processGO:00067532830.023
positive regulation of gene expressionGO:00106282440.023
positive regulation of rna metabolic processGO:00512542030.023
response to carbohydrateGO:00097431830.023
growthGO:00400071650.022
regulation of phosphorylationGO:00423252480.022
eye morphogenesisGO:004859240.022
regulation of cell differentiationGO:00455953200.022
positive regulation of transcription dna templatedGO:00458931970.022
response to bacteriumGO:00096172000.022
response to nutrientGO:00075842480.022
axis specificationGO:000979840.022
dendrite morphogenesisGO:0048813430.021
organophosphate biosynthetic processGO:00904071430.021
anterior posterior pattern specificationGO:000995210.021
multicellular organismal reproductive processGO:00486092330.021
single organism intracellular transportGO:19025821660.021
cellular response to growth factor stimulusGO:00713631620.021
localization of cellGO:00516742020.021
cellular response to organic cyclic compoundGO:00714072020.021
positive regulation of molecular functionGO:00440932300.021
nucleoside phosphate biosynthetic processGO:19012931020.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
regulation of catabolic processGO:00098941130.021
regulation of homeostatic processGO:00328441010.021
ion homeostasisGO:00508012120.021
response to other organismGO:00517072200.021
negative regulation of response to stimulusGO:00485851550.020
epithelium developmentGO:0060429960.020
head developmentGO:00603222470.020
response to peptide hormoneGO:00434342780.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
nucleobase containing small molecule metabolic processGO:00550863160.020
response to glucoseGO:00097491360.020
generation of precursor metabolites and energyGO:0006091620.020
cell adhesionGO:00071551100.020
multicellular organism growthGO:003526410.020
regulation of ion transportGO:00432692450.020
single organism reproductive processGO:00447022970.020
intracellular transportGO:00469071850.020
response to cytokineGO:00340972150.020
protein oligomerizationGO:00512591910.020
positive regulation of phosphorylationGO:00423271770.019
regulation of protein modification processGO:00313991940.019
dendrite developmentGO:0016358720.019
regulation of anatomical structure morphogenesisGO:00226031410.019
single organism organelle organizationGO:19025891800.019
cellular response to cytokine stimulusGO:00713451270.019
brain developmentGO:00074202470.019
nucleotide metabolic processGO:00091172790.019
negative regulation of cell deathGO:00605482290.019
cellular amino acid metabolic processGO:00065201070.019
cell projection morphogenesisGO:00488581230.019
negative regulation of cellular biosynthetic processGO:00313271610.019
gastrulationGO:000736920.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
tube developmentGO:0035295890.018
carbohydrate metabolic processGO:00059751300.018
regulation of cellular protein metabolic processGO:00322682670.018
cell growthGO:00160491040.018
negative regulation of apoptotic processGO:00430661810.018
purine ribonucleotide metabolic processGO:00091502270.018
response to tumor necrosis factorGO:0034612560.018
response to peptideGO:19016522920.018
vesicle mediated transportGO:00161921810.018
cellular chemical homeostasisGO:00550822470.018
ribose phosphate metabolic processGO:00196932350.018
regulation of cell developmentGO:00602842630.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
carbohydrate derivative biosynthetic processGO:19011371240.018
single organism carbohydrate metabolic processGO:00447231180.018
positive regulation of cell developmentGO:00107201760.018
response to lipopolysaccharideGO:00324961910.018
cellular response to organonitrogen compoundGO:00714171970.018
positive regulation of signalingGO:00230562700.018
positive regulation of macromolecule biosynthetic processGO:00105572470.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
regulation of nervous system developmentGO:00519602640.017
cellular homeostasisGO:00197252520.017
reproductive system developmentGO:00614581280.017
regulation of neuron deathGO:19012141150.017
response to external biotic stimulusGO:00432072210.017
protein localizationGO:00081041910.017
circulatory system developmentGO:00723591340.017
response to monosaccharideGO:00342841590.017
developmental process involved in reproductionGO:00030061590.017
response to corticosteroidGO:00319602350.017
regulation of cellular amine metabolic processGO:003323880.017
regulation of growthGO:00400081050.017
regulation of anatomical structure sizeGO:00900661350.017
positive regulation of cellular amine metabolic processGO:003324030.017
negative regulation of programmed cell deathGO:00430691830.017
ribonucleotide metabolic processGO:00092592310.017
response to glucocorticoidGO:00513842230.016
response to acid chemicalGO:00011012220.016
response to molecule of bacterial originGO:00022371940.016
cellular component morphogenesisGO:00329891550.016
regulation of intracellular signal transductionGO:19025312180.016
purine containing compound metabolic processGO:00725212530.016
glycolytic processGO:0006096170.016
cellular response to nitrogen compoundGO:19016992100.016
response to mechanical stimulusGO:00096121340.016
positive regulation of neurogenesisGO:00507691650.016
embryonic pattern specificationGO:000988010.016
circadian rhythmGO:0007623880.016
positive regulation of phosphate metabolic processGO:00459372620.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of cell migrationGO:00303341280.016
cell motilityGO:00488702020.016
reproductive structure developmentGO:00486081280.016
multicellular organism reproductionGO:00325042330.016
regulation of locomotionGO:00400121480.016
oxidation reduction processGO:00551143040.016
synaptic growth at neuromuscular junctionGO:005112410.016
response to oxidative stressGO:00069791860.016
regulation of protein metabolic processGO:00512462890.016
action potentialGO:0001508540.016
negative regulation of gene expressionGO:00106291990.016
regulation of canonical wnt signaling pathwayGO:006082840.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
motor neuron axon guidanceGO:000804510.016
ribose phosphate biosynthetic processGO:0046390870.015
regulation of system processGO:00440572080.015
regulation of neurogenesisGO:00507672470.015
forebrain developmentGO:0030900980.015
cellular response to peptideGO:19016531330.015
amine metabolic processGO:0009308380.015
response to biotic stimulusGO:00096072260.015
development of primary sexual characteristicsGO:00451371070.015
response to hexoseGO:00097461440.015
response to radiationGO:00093141370.015
transmission of nerve impulseGO:0019226420.015
regulation of phosphorus metabolic processGO:00511743490.015
positive regulation of cell differentiationGO:00455972170.015
regulation of nucleotide metabolic processGO:00061401170.015
cardiovascular system developmentGO:00723581340.015
regulation of cellular localizationGO:00603412630.015
response to ketoneGO:19016541820.015
regenerationGO:00310991630.015
cellular protein localizationGO:00346131220.015
positive regulation of cell communicationGO:00106472710.015
purine ribonucleoside metabolic processGO:00461281680.015
response to insulinGO:00328681330.014
lipid storageGO:001991510.014
sex differentiationGO:00075481130.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
cellular lipid metabolic processGO:00442552080.014
carbohydrate catabolic processGO:0016052400.014
regulation of synaptic transmissionGO:00508041410.014
purine nucleoside metabolic processGO:00422781690.014
regulation of membrane potentialGO:00423911100.014
multicellular organismal signalingGO:0035637440.014
cellular response to external stimulusGO:00714961180.014
response to ethanolGO:00454711620.014
organ morphogenesisGO:0009887750.014
organic cyclic compound catabolic processGO:19013611750.014
regulation of hormone levelsGO:00108171870.014
sexual reproductionGO:00199531480.014
circulatory system processGO:00030131830.014
purine nucleotide metabolic processGO:00061632290.014
cellular response to lipidGO:00713962010.014
cell part morphogenesisGO:00329901230.014
multi organism reproductive processGO:00447032620.014
single organism cellular localizationGO:19025801020.014
cognitionGO:0050890920.014
protein heterooligomerizationGO:0051291890.014
negative regulation of molecular functionGO:00440921330.014
cellular response to insulin stimulusGO:0032869810.014
ribonucleoside metabolic processGO:00091191740.014
negative regulation of protein metabolic processGO:00512481140.014
positive regulation of signal transductionGO:00099671750.014
nucleoside metabolic processGO:00091161790.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
positive regulation of cell migrationGO:0030335960.014
monosaccharide metabolic processGO:0005996610.013
regulation of catalytic activityGO:00507903040.013
small gtpase mediated signal transductionGO:0007264360.013
regulation of ion transmembrane transportGO:00347651210.013
cytoplasmic transportGO:00164821150.013
positive regulation of cellular protein metabolic processGO:00322701670.013
carbohydrate homeostasisGO:0033500750.013
regulation of cell motilityGO:20001451310.013
urogenital system developmentGO:0001655780.013
ras protein signal transductionGO:0007265290.013
organonitrogen compound catabolic processGO:19015651790.013
anion transportGO:00068201780.013
cellular response to oxidative stressGO:0034599760.013
cation transmembrane transportGO:00986552630.013
aromatic compound catabolic processGO:00194391680.013
response to metal ionGO:00100382530.013
cellular response to stressGO:00335542690.013
defense responseGO:00069521940.013
ribonucleotide catabolic processGO:00092611360.013
positive regulation of nervous system developmentGO:00519621780.013
regulation of cell growthGO:0001558850.013
inorganic ion transmembrane transportGO:00986602290.013
inorganic cation transmembrane transportGO:00986622020.013
negative regulation of cellular protein metabolic processGO:00322691060.013
heart morphogenesisGO:000300730.013
metal ion homeostasisGO:00550651860.012
gonad developmentGO:00084061040.012
regulation of protein phosphorylationGO:00019321830.012
positive regulation of protein modification processGO:00314011420.012
regulation of purine nucleotide biosynthetic processGO:1900371460.012
positive regulation of apoptotic processGO:00430651540.012
cellular macromolecule localizationGO:00707271220.012
regulation of neuron projection developmentGO:00109751610.012
anion transmembrane transportGO:0098656770.012
regulation of cellular catabolic processGO:00313291010.012
cellular cation homeostasisGO:00300031800.012
regulation of cell projection organizationGO:00313441750.012
signal transduction by phosphorylationGO:00230141440.012
cellular nitrogen compound catabolic processGO:00442701630.012
gliogenesisGO:0042063930.012
muscle structure developmentGO:0061061870.012
establishment of protein localizationGO:00451841410.012
regulation of metal ion transportGO:00109591180.012
dna metabolic processGO:0006259960.012
multicellular organismal homeostasisGO:0048871490.012
glycosyl compound metabolic processGO:19016571820.012
response to toxic substanceGO:00096361330.012
response to woundingGO:00096112540.012
regulation of synaptic plasticityGO:0048167700.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
cellular response to biotic stimulusGO:0071216590.012
calcium ion homeostasisGO:00550741620.012
blood circulationGO:00080151830.012
positive regulation of ion transportGO:0043270940.012
monovalent inorganic cation transportGO:00156721720.012
organic anion transportGO:00157111320.012
peptidyl amino acid modificationGO:00181931260.012
negative regulation of signal transductionGO:0009968830.012
cellular response to peptide hormone stimulusGO:00713751200.012
glucose homeostasisGO:0042593750.012
negative regulation of transportGO:00510511360.011
salivary gland developmentGO:000743130.011
negative regulation of developmental processGO:00510931250.011
response to estradiolGO:00323551640.011
peptide transportGO:0015833970.011
proteolysisGO:00065081750.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
positive regulation of protein metabolic processGO:00512471780.011
divalent metal ion transportGO:00708381320.011
nucleotide biosynthetic processGO:0009165980.011
regulation of neuron differentiationGO:00456642080.011
nucleoside triphosphate metabolic processGO:00091411440.011
heterocycle catabolic processGO:00467001670.011
purine nucleotide biosynthetic processGO:0006164830.011
secretion by cellGO:00329402480.011
negative regulation of multicellular organismal processGO:00512412030.011
regulation of transmembrane transportGO:00347621220.011
calcium ion transportGO:00068161310.011
cellular metal ion homeostasisGO:00068751720.011
monocarboxylic acid metabolic processGO:00327871520.011
negative regulation of rna biosynthetic processGO:19026791180.011
regulation of proteasomal protein catabolic processGO:006113640.011
response to interleukin 1GO:0070555550.011
divalent inorganic cation homeostasisGO:00725071650.011
positive regulation of phosphorus metabolic processGO:00105622620.011
maintenance of locationGO:0051235170.011
axonogenesisGO:0007409710.011
camera type eye morphogenesisGO:004859320.011
neural crest cell differentiationGO:001403320.011
regulation of purine nucleotide metabolic processGO:19005421150.011
ribonucleotide biosynthetic processGO:0009260850.011
positive regulation of cellular component organizationGO:00511302000.011
cell cycleGO:00070491010.011
mesoderm developmentGO:000749820.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
olfactory behaviorGO:004204820.011
ossificationGO:0001503700.010
synaptic vesicle endocytosisGO:004848840.010
signal releaseGO:00230611450.010
response to reactive oxygen speciesGO:00003021200.010
regulation of calcium ion transportGO:0051924770.010
cellular carbohydrate metabolic processGO:0044262720.010
purine containing compound biosynthetic processGO:0072522850.010
neuromuscular synaptic transmissionGO:000727420.010
retina morphogenesis in camera type eyeGO:006004210.010
positive regulation of transportGO:00510502450.010
positive regulation of catabolic processGO:0009896780.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
response to purine containing compoundGO:00140741260.010
response to vitaminGO:00332731310.010
single organism cell adhesionGO:0098602460.010
regulation of organelle organizationGO:0033043800.010
positive regulation of neuron differentiationGO:00456661260.010
reactive oxygen species metabolic processGO:0072593370.010
nucleotide catabolic processGO:00091661390.010
neuromuscular processGO:005090520.010
muscle tissue developmentGO:0060537580.010
organophosphate catabolic processGO:00464341480.010
gamete generationGO:00072761240.010
muscle system processGO:00030121150.010
gland developmentGO:00487321550.010
response to temperature stimulusGO:0009266940.010
positive regulation of cellular catabolic processGO:0031331710.010

Lrrc8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
eye and adnexa diseaseDOID:149200.010
sensory system diseaseDOID:005015500.010