Rattus norvegicus

234 known processes

Pla2g4a

phospholipase A2, group IVA (cytosolic, calcium-dependent)

(Aliases: Pla2c,Pla2g4,cPLA2)

Pla2g4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to biotic stimulusGO:00096072260.957
response to external biotic stimulusGO:00432072210.943
response to other organismGO:00517072200.917
response to bacteriumGO:00096172000.858
response to lipopolysaccharideGO:00324961910.849
response to molecule of bacterial originGO:00022371940.774
inflammatory responseGO:00069541500.748
cellular response to oxygen containing compoundGO:19017013860.710
cellular response to lipidGO:00713962010.655
response to cytokineGO:00340972150.642
regulation of cytokine productionGO:0001817560.587
cellular response to organic cyclic compoundGO:00714072020.517
positive regulation of interleukin 1 beta secretionGO:005071830.515
immune system processGO:00023762040.491
defense responseGO:00069521940.483
tissue developmentGO:00098882520.445
apoptotic processGO:00069153810.444
lipid metabolic processGO:00066292830.412
cytokine productionGO:0001816610.390
single organism reproductive processGO:00447022970.375
response to toxic substanceGO:00096361330.374
Mouse
response to hypoxiaGO:00016662310.366
cell migrationGO:00164771970.357
regulation of apoptotic processGO:00429813350.349
agingGO:00075682410.343
positive regulation of response to stimulusGO:00485842850.338
chemotaxisGO:0006935660.323
regulation of programmed cell deathGO:00430673410.310
positive regulation of protein transportGO:0051222410.306
reproductive structure developmentGO:00486081280.298
cellular response to lipopolysaccharideGO:0071222550.290
innate immune responseGO:0045087350.286
cellular component movementGO:00069282480.284
regulation of response to external stimulusGO:00321011060.282
positive regulation of cell communicationGO:00106472710.279
anatomical structure morphogenesisGO:00096532980.278
cellular response to steroid hormone stimulusGO:0071383930.273
positive regulation of response to external stimulusGO:0032103510.271
cellular response to molecule of bacterial originGO:0071219560.260
positive regulation of retinal cell programmed cell deathGO:004667010.255
response to amino acidGO:0043200750.254
immune responseGO:00069551040.250
secretionGO:00469033070.248
Mouse
regulation of rna biosynthetic processGO:20011413810.248
rna metabolic processGO:00160704060.246
intracellular signal transductionGO:00355563140.243
acute inflammatory response to non antigenic stimulusGO:000252520.238
rna biosynthetic processGO:00327743800.231
positive regulation of i kappab kinase nf kappab signalingGO:004312380.230
response to temperature stimulusGO:0009266940.230
locomotionGO:00400112370.230
regulation of secretionGO:00510462240.219
positive regulation of intracellular signal transductionGO:19025331380.217
regulation of cellular localizationGO:00603412630.216
response to oxidative stressGO:00069791860.216
regulation of multicellular organismal developmentGO:20000263760.215
response to oxygen levelsGO:00704822650.214
response to glucocorticoidGO:00513842230.211
female sex differentiationGO:0046660590.210
positive regulation of cytokine secretionGO:005071590.209
positive regulation of apoptotic processGO:00430651540.205
response to mechanical stimulusGO:00096121340.202
response to corticosteroidGO:00319602350.202
cellular response to cytokine stimulusGO:00713451270.201
regulation of nucleic acid templated transcriptionGO:19035063800.199
homeostatic processGO:00425923310.197
programmed cell deathGO:00125013920.192
multicellular organismal reproductive processGO:00486092330.192
positive regulation of signalingGO:00230562700.191
positive regulation of transportGO:00510502450.191
multicellular organism reproductionGO:00325042330.185
regulation of anatomical structure morphogenesisGO:00226031410.181
positive regulation of immune system processGO:0002684900.178
regulation of chemotaxisGO:0050920290.178
regenerationGO:00310991630.177
luteolysisGO:000155450.176
positive regulation of interleukin 1 secretionGO:005071630.175
positive regulation of programmed cell deathGO:00430681570.171
response to insulinGO:00328681330.171
response to estradiolGO:00323551640.165
reproductive processGO:00224143720.163
positive regulation of cytokine productionGO:0001819420.162
positive regulation of locomotionGO:00400171020.161
interleukin 1 beta secretionGO:005070230.158
cellular response to stressGO:00335542690.158
response to cobalt ionGO:0032025120.158
macromolecule localizationGO:00330362520.157
Mouse
response to woundingGO:00096112540.157
cellular response to insulin stimulusGO:0032869810.157
regulation of immune system processGO:00026821230.155
developmental process involved in reproductionGO:00030061590.154
response to estrogenGO:00436272320.153
response to ethanolGO:00454711620.150
response to tumor necrosis factorGO:0034612560.149
cellular response to peptideGO:19016531330.148
positive regulation of cell deathGO:00109421840.148
response to heatGO:0009408600.147
secretion by cellGO:00329402480.144
enzyme linked receptor protein signaling pathwayGO:00071671160.142
regulation of protein secretionGO:0050708280.136
neuron differentiationGO:00301823680.136
negative regulation of cellular metabolic processGO:00313242810.136
regulation of establishment of protein localizationGO:0070201690.134
positive regulation of cell proliferationGO:00082842490.133
protein transportGO:00150311320.132
response to hydrogen peroxideGO:0042542890.131
positive regulation of cellular biosynthetic processGO:00313282950.131
positive regulation of signal transductionGO:00099671750.127
regulation of secretion by cellGO:19035302080.127
regulation of interleukin 1 secretionGO:005070430.126
positive regulation of macromolecule biosynthetic processGO:00105572470.122
regulation of behaviorGO:0050795610.121
regulation of intracellular signal transductionGO:19025312180.120
positive regulation of protein metabolic processGO:00512471780.120
leukocyte activationGO:0045321760.119
regulation of signal transductionGO:00099663180.119
regulation of interleukin 1 beta secretionGO:005070630.119
cellular response to endogenous stimulusGO:00714953770.119
multi organism reproductive processGO:00447032620.118
response to decreased oxygen levelsGO:00362932370.117
reproductive system developmentGO:00614581280.117
positive regulation of cellular protein metabolic processGO:00322701670.114
positive regulation of biosynthetic processGO:00098913190.113
cellular metal ion homeostasisGO:00068751720.111
neurological system processGO:00508772190.107
cytokine mediated signaling pathwayGO:0019221430.106
positive regulation of secretion by cellGO:19035321280.105
carboxylic acid metabolic processGO:00197522890.102
reproductionGO:00000032450.101
tube developmentGO:0035295890.099
response to peptideGO:19016522920.099
response to peptide hormoneGO:00434342780.099
positive regulation of cell motilityGO:2000147970.098
cellular response to organonitrogen compoundGO:00714171970.097
response to radiationGO:00093141370.096
regulation of cell proliferationGO:00421273590.095
negative regulation of multicellular organismal processGO:00512412030.095
positive regulation of cellular component movementGO:00512721020.093
response to acid chemicalGO:00011012220.093
localization of cellGO:00516742020.093
signal transduction by phosphorylationGO:00230141440.092
response to nutrientGO:00075842480.091
positive regulation of secretionGO:00510471400.091
negative regulation of nitrogen compound metabolic processGO:00511721610.090
immune response regulating signaling pathwayGO:0002764190.090
cognitionGO:0050890920.089
regulation of molecular functionGO:00650093980.089
cellular response to hormone stimulusGO:00328702470.089
regulation of smooth muscle cell proliferationGO:0048660750.088
acute inflammatory responseGO:0002526580.088
response to ketoneGO:19016541820.087
positive regulation of multicellular organismal processGO:00512403870.087
carbohydrate derivative metabolic processGO:19011353460.087
cell motilityGO:00488702020.087
transcription dna templatedGO:00063513770.087
positive regulation of intracellular protein transportGO:0090316200.087
nucleic acid templated transcriptionGO:00976593790.087
response to fluid shear stressGO:0034405160.086
neuron deathGO:00709971270.086
signal releaseGO:00230611450.085
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.084
regulation of protein metabolic processGO:00512462890.083
organic anion transportGO:00157111320.083
Mouse
oxoacid metabolic processGO:00434362900.082
ovulation cycle processGO:0022602500.082
organophosphate metabolic processGO:00196373700.082
neuron developmentGO:00486662860.082
peptidyl tyrosine phosphorylationGO:0018108720.082
cellular lipid metabolic processGO:00442552080.081
regulation of rna metabolic processGO:00512523910.081
response to inorganic substanceGO:00100353770.081
cell projection organizationGO:00300303020.081
cellular response to external stimulusGO:00714961180.079
gamete generationGO:00072761240.079
neuron projection developmentGO:00311752730.079
vesicle mediated transportGO:00161921810.078
regulation of protein localizationGO:0032880810.076
cellular ketone metabolic processGO:0042180510.076
glial cell apoptotic processGO:003434980.075
negative regulation of macromolecule biosynthetic processGO:00105581480.073
female gonad developmentGO:0008585530.073
cellular response to reactive oxygen speciesGO:0034614550.073
regulation of locomotionGO:00400121480.072
cellular response to peptide hormone stimulusGO:00713751200.072
response to organophosphorusGO:00466831020.072
sensory organ developmentGO:0007423740.072
cellular response to corticosteroid stimulusGO:0071384690.071
cellular response to nitrogen compoundGO:19016992100.071
regulation of tumor necrosis factor productionGO:0032680130.070
positive regulation of cell migrationGO:0030335960.069
response to gamma radiationGO:0010332240.069
organ regenerationGO:00311001010.068
positive regulation of molecular functionGO:00440932300.068
peptidyl amino acid modificationGO:00181931260.068
regulation of phosphorus metabolic processGO:00511743490.067
regulation of cell differentiationGO:00455953200.066
positive regulation of nitrogen compound metabolic processGO:00511733340.066
regulation of catalytic activityGO:00507903040.066
cellular response to glucocorticoid stimulusGO:0071385680.066
positive regulation of nucleobase containing compound metabolic processGO:00459353190.065
response to interferon gammaGO:0034341200.063
regulation of phosphorylationGO:00423252480.063
response to high density lipoprotein particleGO:005509920.063
regulation of system processGO:00440572080.063
cell type specific apoptotic processGO:00972851340.063
negative regulation of metabolic processGO:00098923310.062
cellular response to platelet derived growth factor stimulusGO:003612070.062
regulation of cellular ketone metabolic processGO:0010565270.061
central nervous system developmentGO:00074173110.061
single organism intracellular transportGO:19025821660.061
response to alkaloidGO:00432791320.061
muscle cell proliferationGO:0033002840.061
catabolic processGO:00090563510.060
response to vitaminGO:00332731310.059
negative regulation of macromolecule metabolic processGO:00106052600.059
behaviorGO:00076102050.059
response to growth factorGO:00708481890.059
ovulation cycleGO:0042698670.058
positive regulation of catalytic activityGO:00430851840.057
positive regulation of immune responseGO:0050778420.057
regulation of response to stressGO:00801341260.057
response to extracellular stimulusGO:00099913800.056
regulation of cellular component organizationGO:00511283680.056
learning or memoryGO:0007611900.055
protein phosphorylationGO:00064683450.055
protein autophosphorylationGO:0046777660.055
positive regulation of developmental processGO:00510942830.054
positive regulation of cellular component organizationGO:00511302000.054
regulation of cytokine secretionGO:0050707110.054
blood vessel developmentGO:0001568690.054
development of primary sexual characteristicsGO:00451371070.053
myeloid leukocyte activationGO:0002274360.053
regulation of hormone levelsGO:00108171870.052
growthGO:00400071650.052
positive regulation of protein secretionGO:0050714190.052
activation of immune responseGO:0002253260.052
macromolecular complex subunit organizationGO:00439333390.052
regulation of cell developmentGO:00602842630.052
cell cycleGO:00070491010.051
cardiovascular system developmentGO:00723581340.051
regulation of reactive oxygen species metabolic processGO:2000377260.051
regulation of muscle system processGO:0090257790.051
memoryGO:0007613540.051
regulation of protein transportGO:0051223680.050
nitrogen compound transportGO:00717052290.050
cell cell signalingGO:00072673350.049
cellular component morphogenesisGO:00329891550.049
cellular amino acid metabolic processGO:00065201070.049
microglial cell activationGO:0001774140.049
positive regulation of cell differentiationGO:00455972170.049
development of primary female sexual characteristicsGO:0046545560.049
cell morphogenesisGO:00009021420.048
retinal cell programmed cell deathGO:004666610.048
gonad developmentGO:00084061040.048
cellular response to oxidative stressGO:0034599760.047
protein complex assemblyGO:00064612630.047
regulation of transcription dna templatedGO:00063553740.047
hormone transportGO:00099141210.046
cellular response to lipoteichoic acidGO:007122310.046
response to monosaccharideGO:00342841590.046
response to transition metal nanoparticleGO:19902671220.046
regulation of cellular amino acid metabolic processGO:000652120.046
regulation of cell motilityGO:20001451310.046
fever generationGO:000166090.045
camera type eye developmentGO:0043010480.045
positive regulation of phosphorylationGO:00423271770.045
response to metal ionGO:00100382530.045
protein complex subunit organizationGO:00718223020.044
organonitrogen compound biosynthetic processGO:19015661670.044
negative regulation of nucleic acid templated transcriptionGO:19035071170.044
divalent inorganic cation homeostasisGO:00725071650.044
renal system developmentGO:0072001670.044
response to carbohydrateGO:00097431830.043
regulation of homeostatic processGO:00328441010.043
regulation of blood pressureGO:0008217830.043
negative regulation of rna metabolic processGO:00512531230.043
blood circulationGO:00080151830.043
cytokine secretionGO:0050663150.043
negative regulation of cellular biosynthetic processGO:00313271610.042
response to hexoseGO:00097461440.042
protein secretionGO:0009306340.042
cellular divalent inorganic cation homeostasisGO:00725031620.042
positive regulation of protein kinase activityGO:0045860730.042
positive regulation of phosphorus metabolic processGO:00105622620.042
regulation of cell migrationGO:00303341280.041
mapk cascadeGO:00001651400.041
positive regulation of interleukin 1 beta productionGO:003273160.041
cellular response to growth factor stimulusGO:00713631620.041
smooth muscle cell proliferationGO:0048659770.041
negative regulation of programmed cell deathGO:00430691830.041
regulation of cellular component movementGO:00512701500.041
sex differentiationGO:00075481130.040
positive regulation of defense responseGO:0031349370.040
cation homeostasisGO:00550801950.040
steroid metabolic processGO:0008202730.040
positive regulation of cytoplasmic transportGO:1903651320.040
cellular catabolic processGO:00442482950.040
response to reactive oxygen speciesGO:00003021200.040
organic substance catabolic processGO:19015753160.040
positive regulation of leukocyte migrationGO:0002687210.040
positive regulation of protein modification processGO:00314011420.039
regulation of cellular protein metabolic processGO:00322682670.039
cellular response to abiotic stimulusGO:0071214850.039
cellular response to biotic stimulusGO:0071216590.039
cellular cation homeostasisGO:00300031800.039
regulation of phosphate metabolic processGO:00192203490.039
eye morphogenesisGO:004859240.039
regulation of kinase activityGO:00435491170.039
intracellular transportGO:00469071850.039
cellular ion homeostasisGO:00068731840.039
regulation of retinal cell programmed cell deathGO:004666810.039
cell activationGO:0001775970.038
immune response activating signal transductionGO:0002757150.038
single organism behaviorGO:00447081300.038
purine nucleoside metabolic processGO:00422781690.038
positive regulation of rna metabolic processGO:00512542030.038
positive regulation of smooth muscle cell proliferationGO:0048661510.038
negative regulation of gene expressionGO:00106291990.038
cellular component biogenesisGO:00440853680.038
negative regulation of nucleobase containing compound metabolic processGO:00459341530.038
regulation of membrane potentialGO:00423911100.037
cellular amine metabolic processGO:0044106380.037
positive regulation of cellular amino acid metabolic processGO:004576410.037
cellular response to tumor necrosis factorGO:0071356460.037
establishment of protein localizationGO:00451841410.037
positive regulation of homeostatic processGO:0032846490.036
regulation of cellular amine metabolic processGO:003323880.036
peptidyl tyrosine modificationGO:0018212720.036
positive regulation of rna biosynthetic processGO:19026801970.036
single organism organelle organizationGO:19025891800.036
lung developmentGO:0030324430.036
positive regulation of cytosolic calcium ion concentrationGO:00072041220.035
sexual reproductionGO:00199531480.035
cellular response to acid chemicalGO:0071229750.035
muscle system processGO:00030121150.034
cellular response to mechanical stimulusGO:0071260480.034
regulation of fat cell differentiationGO:004559830.034
aromatic compound catabolic processGO:00194391680.034
anterior posterior pattern specificationGO:000995210.034
cellular calcium ion homeostasisGO:00068741600.034
negative regulation of biosynthetic processGO:00098901680.033
respiratory system developmentGO:0060541450.033
regulation of cell activationGO:0050865500.033
ion homeostasisGO:00508012120.033
protein maturationGO:0051604680.033
regulation of mapk cascadeGO:00434081160.032
purine ribonucleoside metabolic processGO:00461281680.032
divalent metal ion transportGO:00708381320.032
activation of cysteine type endopeptidase activityGO:009720240.032
protein localizationGO:00081041910.031
positive regulation of chemokine productionGO:003272240.031
vasculature developmentGO:0001944700.031
neuron apoptotic processGO:0051402880.031
nucleoside phosphate catabolic processGO:19012921400.031
regulation of smooth muscle contractionGO:0006940290.031
ribonucleoside metabolic processGO:00091191740.031
regulation of neurogenesisGO:00507672470.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.031
regulation of synaptic transmissionGO:00508041410.030
response to anoxiaGO:003405940.030
nucleobase containing small molecule metabolic processGO:00550863160.030
hormone secretionGO:00468791150.030
purine containing compound metabolic processGO:00725212530.030
cation transportGO:00068123820.030
positive regulation of kinase activityGO:0033674770.030
endocytosisGO:0006897840.030
amide biosynthetic processGO:0043604100.030
gliogenesisGO:0042063930.030
peptide transportGO:0015833970.030
cell part morphogenesisGO:00329901230.029
single organism catabolic processGO:00447122830.029
organelle organizationGO:00069962660.029
regulation of lymphocyte migrationGO:200040110.029
nucleoside phosphate metabolic processGO:00067532830.029
anion transportGO:00068201780.029
Mouse
regulation of inflammatory responseGO:0050727480.029
transmembrane transportGO:00550854120.029
positive regulation of cell developmentGO:00107201760.028
regulation of i kappab kinase nf kappab signalingGO:0043122130.028
cellular homeostasisGO:00197252520.028
ribose phosphate metabolic processGO:00196932350.028
macrophage chemotaxisGO:004824620.028
positive regulation of transcription dna templatedGO:00458931970.028
fatty acid derivative metabolic processGO:1901568380.028
smooth muscle contractionGO:0006939370.027
unsaturated fatty acid metabolic processGO:0033559390.027
protein complex biogenesisGO:00702712630.027
urogenital system developmentGO:0001655780.027
regulation of tube sizeGO:0035150890.027
neuronal action potentialGO:0019228350.027
glycosyl compound metabolic processGO:19016571820.027
negative regulation of transcription dna templatedGO:00458921160.027
anatomical structure formation involved in morphogenesisGO:0048646830.027
regulation of neuron apoptotic processGO:0043523830.027
negative regulation of protein metabolic processGO:00512481140.026
response to purine containing compoundGO:00140741260.026
amide transportGO:00428861050.026
negative regulation of rna biosynthetic processGO:19026791180.026
regulation of leukocyte migrationGO:0002685240.026
single organism biosynthetic processGO:00447113420.026
response to fatty acidGO:0070542650.026
positive regulation of leukocyte chemotaxisGO:0002690100.026
mononuclear cell proliferationGO:0032943290.026
ion transmembrane transportGO:00342203650.026
positive regulation of transcription factor import into nucleusGO:004299340.025
calcium ion homeostasisGO:00550741620.025
regulation of cell cycleGO:0051726730.025
head developmentGO:00603222470.025
organic acid metabolic processGO:00060822920.025
purine ribonucleotide metabolic processGO:00091502270.025
cellular response to alcoholGO:0097306870.025
b cell activation involved in immune responseGO:000231210.025
positive regulation of neuron deathGO:1901216430.025
response to testosteroneGO:0033574550.025
positive regulation of cellular amine metabolic processGO:003324030.025
positive regulation of protein phosphorylationGO:00019341350.025
synaptic transmissionGO:00072682350.024
positive regulation of behaviorGO:0048520380.024
regulation of blood circulationGO:19035221100.024
response to endoplasmic reticulum stressGO:0034976100.024
axonogenesisGO:0007409710.024
negative regulation of signalingGO:00230571570.024
brain developmentGO:00074202470.024
negative regulation of apoptotic processGO:00430661810.024
response to glucoseGO:00097491360.024
nucleobase containing compound catabolic processGO:00346551520.024
regulation of calcium ion transportGO:0051924770.024
ribonucleotide metabolic processGO:00092592310.023
chemical homeostasisGO:00488782920.023
organ morphogenesisGO:0009887750.023
cellular component assemblyGO:00226073600.023
wound healingGO:00420601220.023
negative regulation of cell proliferationGO:00082851190.023
organic cyclic compound catabolic processGO:19013611750.023
digestive tract developmentGO:0048565390.023
negative regulation of signal transductionGO:0009968830.023
macromolecular complex assemblyGO:00650032730.023
reactive nitrogen species metabolic processGO:200105710.023
cellular response to interleukin 1GO:0071347370.023
lens development in camera type eyeGO:0002088130.023
response to nutrient levelsGO:00316673700.023
response to dexamethasoneGO:0071548490.023
b cell differentiationGO:003018320.023
positive regulation of synaptic transmissionGO:0050806620.022
monocarboxylic acid metabolic processGO:00327871520.022
spermatogenesisGO:0007283990.022
acute phase responseGO:0006953200.022
amine metabolic processGO:0009308380.022
taxisGO:0042330670.022
positive regulation of transferase activityGO:0051347810.022
oxidation reduction processGO:00551143040.022
single organism cellular localizationGO:19025801020.022
response to hyperoxiaGO:0055093450.022
male gamete generationGO:0048232990.022
positive regulation of neuron apoptotic processGO:0043525330.022
gland developmentGO:00487321550.022
heterocycle catabolic processGO:00467001670.022
regulation of blood vessel sizeGO:0050880890.022
forebrain developmentGO:0030900980.021
pallium developmentGO:0021543420.021
regulation of metal ion transportGO:00109591180.021
positive regulation of interleukin 1 alpha productionGO:003273010.021
positive regulation of mapk cascadeGO:0043410920.021
regulation of dna metabolic processGO:0051052600.021
neural retina developmentGO:000340770.021
negative regulation of cell communicationGO:00106481580.020
transcription from rna polymerase ii promoterGO:00063662520.020
response to electrical stimulusGO:0051602560.020
nucleoside phosphate biosynthetic processGO:19012931020.020
axon developmentGO:0061564960.020
dna metabolic processGO:0006259960.020
ribonucleoside monophosphate metabolic processGO:0009161880.020
response to nicotineGO:0035094510.020
eye developmentGO:0001654500.020
vasculogenesisGO:000157030.020
regulation of protein kinase activityGO:00458591050.020
nucleotide metabolic processGO:00091172790.020
nucleoside metabolic processGO:00091161790.020
circulatory system processGO:00030131830.020
regulation of platelet activationGO:001054320.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
cellular chemical homeostasisGO:00550822470.020
positive regulation of lymphocyte migrationGO:200040310.020
placenta developmentGO:0001890220.019
respiratory tube developmentGO:0030323430.019
purine ribonucleotide catabolic processGO:00091541360.019
positive regulation of nucleocytoplasmic transportGO:0046824170.019
muscle contractionGO:0006936880.019
embryonic placenta developmentGO:000189210.019
regulation of erk1 and erk2 cascadeGO:0070372410.019
positive regulation of tumor necrosis factor productionGO:003276080.019

Pla2g4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:149200.038
eye diseaseDOID:561400.038
sensory system diseaseDOID:005015500.038
nervous system diseaseDOID:86300.038
disease of anatomical entityDOID:700.038