Rattus norvegicus

43 known processes

Enpp2

ectonucleotide pyrophosphatase/phosphodiesterase 2

(Aliases: MGC93258)

Enpp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.201
oxoacid metabolic processGO:00434362900.178
carboxylic acid metabolic processGO:00197522890.143
response to inorganic substanceGO:00100353770.140
cellular amino acid metabolic processGO:00065201070.116
response to metal ionGO:00100382530.112
response to glucocorticoidGO:00513842230.099
central nervous system developmentGO:00074173110.091
response to woundingGO:00096112540.089
catabolic processGO:00090563510.078
single organism biosynthetic processGO:00447113420.075
metal ion transportGO:00300012890.072
response to nutrient levelsGO:00316673700.072
Yeast
response to extracellular stimulusGO:00099913800.070
Yeast
neurological system processGO:00508772190.068
amine metabolic processGO:0009308380.067
cellular amine metabolic processGO:0044106380.064
response to bacteriumGO:00096172000.063
cation transportGO:00068123820.061
head developmentGO:00603222470.060
neuron projection developmentGO:00311752730.058
transmembrane transportGO:00550854120.057
neuron developmentGO:00486662860.055
anatomical structure morphogenesisGO:00096532980.054
cellular ketone metabolic processGO:0042180510.052
tissue developmentGO:00098882520.052
regulation of cellular amine metabolic processGO:003323880.051
nitrogen compound transportGO:00717052290.051
organic hydroxy compound metabolic processGO:19016151150.051
response to ethanolGO:00454711620.050
brain developmentGO:00074202470.050
response to acid chemicalGO:00011012220.049
organic substance catabolic processGO:19015753160.048
regulation of cell projection organizationGO:00313441750.048
regulation of cell developmentGO:00602842630.048
cell projection organizationGO:00300303020.048
response to corticosteroidGO:00319602350.047
regulation of multicellular organismal developmentGO:20000263760.047
cellular catabolic processGO:00442482950.046
regulation of cellular amino acid metabolic processGO:000652120.046
ion transmembrane transportGO:00342203650.046
small molecule catabolic processGO:0044282590.046
behaviorGO:00076102050.045
inorganic ion transmembrane transportGO:00986602290.044
cellular response to endogenous stimulusGO:00714953770.043
transcription from rna polymerase ii promoterGO:00063662520.043
regulation of cellular ketone metabolic processGO:0010565270.043
regulation of signal transductionGO:00099663180.042
regulation of cell differentiationGO:00455953200.041
negative regulation of metabolic processGO:00098923310.041
single organism reproductive processGO:00447022970.041
response to external biotic stimulusGO:00432072210.041
regulation of neurogenesisGO:00507672470.040
response to biotic stimulusGO:00096072260.040
multicellular organismal signalingGO:0035637440.040
inorganic cation transmembrane transportGO:00986622020.040
cation transmembrane transportGO:00986552630.040
negative regulation of macromolecule metabolic processGO:00106052600.039
positive regulation of cell differentiationGO:00455972170.039
transcription dna templatedGO:00063513770.039
nucleic acid templated transcriptionGO:00976593790.039
positive regulation of signalingGO:00230562700.038
divalent inorganic cation transportGO:00725111340.038
regulation of cell proliferationGO:00421273590.037
lipid metabolic processGO:00066292830.037
regulation of apoptotic processGO:00429813350.037
neuron differentiationGO:00301823680.036
regulation of cellular component movementGO:00512701500.036
Human
rna metabolic processGO:00160704060.036
regulation of membrane potentialGO:00423911100.035
cellular component assemblyGO:00226073600.035
protein phosphorylationGO:00064683450.035
positive regulation of developmental processGO:00510942830.034
neuronal action potentialGO:0019228350.034
positive regulation of cell proliferationGO:00082842490.034
regulation of ion transportGO:00432692450.034
regulation of nervous system developmentGO:00519602640.033
cellular response to organic cyclic compoundGO:00714072020.033
agingGO:00075682410.033
positive regulation of neurogenesisGO:00507691650.033
response to purine containing compoundGO:00140741260.033
chemical homeostasisGO:00488782920.032
transmission of nerve impulseGO:0019226420.032
positive regulation of cellular amine metabolic processGO:003324030.031
response to lipopolysaccharideGO:00324961910.031
response to other organismGO:00517072200.031
response to peptide hormoneGO:00434342780.031
positive regulation of nitrogen compound metabolic processGO:00511733340.031
growthGO:00400071650.031
positive regulation of multicellular organismal processGO:00512403870.030
regulation of programmed cell deathGO:00430673410.030
regulation of nucleic acid templated transcriptionGO:19035063800.030
learning or memoryGO:0007611900.030
cellular response to stressGO:00335542690.030
Yeast
cellular homeostasisGO:00197252520.030
apoptotic processGO:00069153810.029
positive regulation of biosynthetic processGO:00098913190.029
positive regulation of neuron projection developmentGO:0010976990.029
regulation of cellular component organizationGO:00511283680.029
regulation of phosphorus metabolic processGO:00511743490.029
positive regulation of response to stimulusGO:00485842850.029
cell motilityGO:00488702020.029
Human
cellular modified amino acid metabolic processGO:0006575610.029
cellular response to organonitrogen compoundGO:00714171970.028
positive regulation of cell communicationGO:00106472710.028
regenerationGO:00310991630.028
homeostatic processGO:00425923310.028
regulation of neuron differentiationGO:00456642080.028
regulation of anatomical structure morphogenesisGO:00226031410.028
regulation of rna metabolic processGO:00512523910.028
organophosphate metabolic processGO:00196373700.028
positive regulation of cell developmentGO:00107201760.028
regulation of phosphate metabolic processGO:00192203490.028
positive regulation of phosphate metabolic processGO:00459372620.028
anion transportGO:00068201780.028
regulation of molecular functionGO:00650093980.027
carbohydrate derivative metabolic processGO:19011353460.027
regulation of neuron projection developmentGO:00109751610.027
positive regulation of nervous system developmentGO:00519621780.027
response to ketoneGO:19016541820.027
negative regulation of multicellular organismal processGO:00512412030.027
intracellular signal transductionGO:00355563140.027
response to organophosphorusGO:00466831020.027
positive regulation of gene expressionGO:00106282440.026
cellular response to oxygen containing compoundGO:19017013860.026
response to radiationGO:00093141370.026
negative regulation of transportGO:00510511360.026
organonitrogen compound catabolic processGO:19015651790.026
lipid biosynthetic processGO:00086101280.026
secretionGO:00469033070.025
cellular component biogenesisGO:00440853680.025
regulation of transcription dna templatedGO:00063553740.025
response to nutrientGO:00075842480.025
rna biosynthetic processGO:00327743800.025
positive regulation of cellular component organizationGO:00511302000.025
eye morphogenesisGO:004859240.025
divalent metal ion transportGO:00708381320.025
positive regulation of phosphorus metabolic processGO:00105622620.025
response to molecule of bacterial originGO:00022371940.025
response to carbohydrateGO:00097431830.025
regulation of protein metabolic processGO:00512462890.025
response to oxidative stressGO:00069791860.025
organonitrogen compound biosynthetic processGO:19015661670.025
action potentialGO:0001508540.024
single organism catabolic processGO:00447122830.024
negative regulation of response to stimulusGO:00485851550.024
fatty acid metabolic processGO:0006631990.024
negative regulation of cell communicationGO:00106481580.024
negative regulation of gene expressionGO:00106291990.024
protein complex biogenesisGO:00702712630.023
positive regulation of cell projection organizationGO:00313461110.023
regulation of cellular protein metabolic processGO:00322682670.023
reproductive processGO:00224143720.023
cellular component movementGO:00069282480.023
Human
regulation of phosphorylationGO:00423252480.023
locomotionGO:00400112370.023
Human
cellular response to nitrogen compoundGO:19016992100.023
programmed cell deathGO:00125013920.023
multi organism reproductive processGO:00447032620.023
oxidation reduction processGO:00551143040.023
positive regulation of cell deathGO:00109421840.023
positive regulation of macromolecule biosynthetic processGO:00105572470.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
positive regulation of molecular functionGO:00440932300.022
neuron deathGO:00709971270.022
secretion by cellGO:00329402480.022
response to alkaloidGO:00432791320.022
regulation of protein phosphorylationGO:00019321830.021
calcium ion transportGO:00068161310.021
positive regulation of cellular biosynthetic processGO:00313282950.021
alcohol metabolic processGO:0006066770.021
response to oxygen levelsGO:00704822650.021
organelle organizationGO:00069962660.021
negative regulation of cellular metabolic processGO:00313242810.021
sulfur compound metabolic processGO:0006790700.021
alpha amino acid metabolic processGO:1901605710.021
cellular chemical homeostasisGO:00550822470.020
cellular lipid metabolic processGO:00442552080.020
regulation of rna biosynthetic processGO:20011413810.020
response to decreased oxygen levelsGO:00362932370.020
cellular calcium ion homeostasisGO:00068741600.020
macromolecular complex assemblyGO:00650032730.020
axon ensheathmentGO:0008366400.020
wound healingGO:00420601220.020
cellular amino acid biosynthetic processGO:0008652320.020
biological adhesionGO:00226101100.020
anion transmembrane transportGO:0098656770.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
multicellular organismal reproductive processGO:00486092330.019
regulation of system processGO:00440572080.019
regulation of hormone levelsGO:00108171870.019
macromolecule localizationGO:00330362520.019
response to transition metal nanoparticleGO:19902671220.019
single organism behaviorGO:00447081300.019
carboxylic acid catabolic processGO:0046395490.019
synaptic transmissionGO:00072682350.019
circulatory system developmentGO:00723591340.019
negative regulation of developmental processGO:00510931250.019
positive regulation of apoptotic processGO:00430651540.019
inflammatory responseGO:00069541500.019
cognitionGO:0050890920.018
regulation of cellular localizationGO:00603412630.018
ras protein signal transductionGO:0007265290.018
macromolecular complex subunit organizationGO:00439333390.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
rhythmic processGO:00485111560.018
regulation of cell migrationGO:00303341280.018
Human
response to peptideGO:19016522920.018
response to estrogenGO:00436272320.018
regulation of protein modification processGO:00313991940.017
single organism carbohydrate metabolic processGO:00447231180.017
regulation of intracellular signal transductionGO:19025312180.017
positive regulation of neuron differentiationGO:00456661260.017
negative regulation of cell deathGO:00605482290.017
nucleoside phosphate metabolic processGO:00067532830.017
Yeast
regulation of catalytic activityGO:00507903040.017
nucleotide metabolic processGO:00091172790.017
cell adhesionGO:00071551100.017
regulation of secretion by cellGO:19035302080.017
multicellular organism growthGO:003526410.017
gliogenesisGO:0042063930.017
regulation of secretionGO:00510462240.017
ensheathment of neuronsGO:0007272400.017
organic acid biosynthetic processGO:0016053830.016
multicellular organism reproductionGO:00325042330.016
positive regulation of programmed cell deathGO:00430681570.016
response to vitaminGO:00332731310.016
ion homeostasisGO:00508012120.016
response to glucoseGO:00097491360.016
organic hydroxy compound transportGO:0015850770.016
regulation of growthGO:00400081050.016
cell morphogenesisGO:00009021420.016
cell cell signalingGO:00072673350.016
positive regulation of cellular protein metabolic processGO:00322701670.016
small gtpase mediated signal transductionGO:0007264360.016
renal system developmentGO:0072001670.016
positive regulation of transportGO:00510502450.016
signal transduction by phosphorylationGO:00230141440.016
localization of cellGO:00516742020.016
Human
response to campGO:0051591910.016
regulation of protein kinase activityGO:00458591050.015
negative regulation of ion transportGO:0043271510.015
carbohydrate derivative biosynthetic processGO:19011371240.015
ribose phosphate metabolic processGO:00196932350.015
regulation of kinase activityGO:00435491170.015
synaptic growth at neuromuscular junctionGO:005112410.015
regulation of response to stressGO:00801341260.015
regulation of neuron deathGO:19012141150.015
negative regulation of signalingGO:00230571570.015
positive regulation of protein metabolic processGO:00512471780.015
hormone metabolic processGO:0042445690.015
positive regulation of phosphorylationGO:00423271770.015
regulation of locomotionGO:00400121480.015
Human
intracellular transportGO:00469071850.015
protein complex assemblyGO:00064612630.015
carboxylic acid transportGO:00469421150.015
positive regulation of signal transductionGO:00099671750.015
negative regulation of transcription dna templatedGO:00458921160.014
cellular ion homeostasisGO:00068731840.014
response to monosaccharideGO:00342841590.014
protein complex subunit organizationGO:00718223020.014
response to aluminum ionGO:0010044100.014
regulation of cellular catabolic processGO:00313291010.014
positive regulation of transcription dna templatedGO:00458931970.014
positive regulation of ion transportGO:0043270940.014
response to cytokineGO:00340972150.014
adult locomotory behaviorGO:000834440.014
defense responseGO:00069521940.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
regulation of calcium ion transportGO:0051924770.014
circulatory system processGO:00030131830.014
sexual reproductionGO:00199531480.014
g protein coupled receptor signaling pathwayGO:00071862420.014
organophosphate biosynthetic processGO:00904071430.014
calcium ion homeostasisGO:00550741620.014
purine containing compound metabolic processGO:00725212530.014
regulation of blood pressureGO:0008217830.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
cation homeostasisGO:00550801950.014
regulation of establishment of planar polarityGO:009017520.014
monovalent inorganic cation transportGO:00156721720.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
cellular response to growth factor stimulusGO:00713631620.013
cellular component morphogenesisGO:00329891550.013
cellular response to hormone stimulusGO:00328702470.013
positive regulation of protein phosphorylationGO:00019341350.013
calcium ion transmembrane transportGO:0070588700.013
monocarboxylic acid metabolic processGO:00327871520.013
kidney developmentGO:0001822670.013
myelinationGO:0042552390.013
organic anion transportGO:00157111320.013
regulation of metal ion transportGO:00109591180.013
developmental growthGO:00485891000.013
cell part morphogenesisGO:00329901230.013
regulation of transmembrane transportGO:00347621220.013
regulation of transferase activityGO:00513381230.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.013
blood circulationGO:00080151830.013
glial cell differentiationGO:0010001650.013
carboxylic acid biosynthetic processGO:0046394830.013
cellular response to external stimulusGO:00714961180.013
Yeast
metanephric comma shaped body morphogenesisGO:007227820.013
positive regulation of protein modification processGO:00314011420.013
negative regulation of programmed cell deathGO:00430691830.013
rho protein signal transductionGO:0007266110.013
regulation of vesicle mediated transportGO:0060627810.013
reproductionGO:00000032450.013
protein oligomerizationGO:00512591910.013
single organism intracellular transportGO:19025821660.013
positive regulation of protein kinase activityGO:0045860730.013
regulation of catabolic processGO:00098941130.012
positive regulation of cell motilityGO:2000147970.012
sensory organ developmentGO:0007423740.012
positive regulation of transferase activityGO:0051347810.012
organic cyclic compound catabolic processGO:19013611750.012
negative regulation of molecular functionGO:00440921330.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
glycosyl compound metabolic processGO:19016571820.012
gland developmentGO:00487321550.012
organic acid catabolic processGO:0016054490.012
organic acid transportGO:00158491160.012
axis specificationGO:000979840.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
regulation of immune system processGO:00026821230.012
proteolysisGO:00065081750.012
endocytosisGO:0006897840.012
response to estradiolGO:00323551640.012
circadian rhythmGO:0007623880.012
cellular response to lipidGO:00713962010.012
positive regulation of intracellular signal transductionGO:19025331380.012
cellular biogenic amine metabolic processGO:0006576300.012
cardiovascular system developmentGO:00723581340.012
metal ion homeostasisGO:00550651860.012
response to hypoxiaGO:00016662310.012
hormone transportGO:00099141210.012
response to retinoic acidGO:0032526630.012
cellular response to abiotic stimulusGO:0071214850.012
small molecule biosynthetic processGO:00442831240.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
cell morphogenesis involved in differentiationGO:00009041190.012
cellular amino acid catabolic processGO:0009063210.012
neuron apoptotic processGO:0051402880.011
cellular response to peptideGO:19016531330.011
taxisGO:0042330670.011
response to fatty acidGO:0070542650.011
ribonucleotide metabolic processGO:00092592310.011
negative regulation of catalytic activityGO:00430861030.011
dephosphorylationGO:0016311980.011
negative regulation of secretionGO:0051048820.011
cytoplasmic transportGO:00164821150.011
purine nucleotide metabolic processGO:00061632290.011
cellular cation homeostasisGO:00300031800.011
gamete generationGO:00072761240.011
response to temperature stimulusGO:0009266940.011
positive regulation of catalytic activityGO:00430851840.011
response to hexoseGO:00097461440.011
vesicle mediated transportGO:00161921810.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
chemotaxisGO:0006935660.011
positive regulation of immune system processGO:0002684900.011
epithelium developmentGO:0060429960.011
response to reactive oxygen speciesGO:00003021200.011
monoamine transportGO:0015844430.011
cell projection morphogenesisGO:00488581230.011
positive regulation of protein serine threonine kinase activityGO:0071902520.011
response to toxic substanceGO:00096361330.011
response to growth factorGO:00708481890.011
negative regulation of apoptotic processGO:00430661810.011
regulation of homeostatic processGO:00328441010.011
positive regulation of kinase activityGO:0033674770.011
negative regulation of cellular protein metabolic processGO:00322691060.011
purine ribonucleotide metabolic processGO:00091502270.011
positive regulation of rna metabolic processGO:00512542030.011
regulation of anatomical structure sizeGO:00900661350.011
regulation of cell growthGO:0001558850.011
mapk cascadeGO:00001651400.011
defense response to gram negative bacteriumGO:005082930.011
divalent inorganic cation homeostasisGO:00725071650.011
positive regulation of mapk cascadeGO:0043410920.011
steroid metabolic processGO:0008202730.011
cellular response to alcoholGO:0097306870.011
response to light stimulusGO:0009416520.011
positive regulation of rna biosynthetic processGO:19026801970.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
response to mechanical stimulusGO:00096121340.011
chromosome segregationGO:000705920.011
establishment of tissue polarityGO:000716420.011
positive regulation of cellular component movementGO:00512721020.011
alpha amino acid catabolic processGO:1901606200.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
neuron projection morphogenesisGO:00488121220.010
purine containing compound biosynthetic processGO:0072522850.010
negative regulation of cell proliferationGO:00082851190.010
cellular response to acid chemicalGO:0071229750.010
glucose homeostasisGO:0042593750.010
positive regulation of map kinase activityGO:0043406460.010
negative regulation of protein metabolic processGO:00512481140.010
cellular response to cytokine stimulusGO:00713451270.010
regulation of ion transmembrane transportGO:00347651210.010
neural crest cell developmentGO:001403220.010
axon developmentGO:0061564960.010

Enpp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.052
disease of metabolismDOID:001466700.052
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
central nervous system diseaseDOID:33100.017
musculoskeletal system diseaseDOID:1700.013
gastrointestinal system diseaseDOID:7700.011