Rattus norvegicus

29 known processes

Dmgdh

dimethylglycine dehydrogenase

(Aliases: Me2GlyDH)

Dmgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201070.562
carboxylic acid metabolic processGO:00197522890.439
positive regulation of multicellular organismal processGO:00512403870.395
coenzyme metabolic processGO:0006732860.349
regulation of cell proliferationGO:00421273590.342
negative regulation of serine type endopeptidase activityGO:190000410.282
negative regulation of serine type peptidase activityGO:190257210.270
oxoacid metabolic processGO:00434362900.235
response to corticosteroidGO:00319602350.234
monocarboxylic acid metabolic processGO:00327871520.226
response to peptide hormoneGO:00434342780.225
cofactor metabolic processGO:0051186950.209
response to extracellular stimulusGO:00099913800.205
response to peptideGO:19016522920.193
response to glucocorticoidGO:00513842230.186
response to vitaminGO:00332731310.175
response to nutrientGO:00075842480.167
hepaticobiliary system developmentGO:0061008900.166
lipid metabolic processGO:00066292830.140
reactive oxygen species metabolic processGO:0072593370.135
steroid metabolic processGO:0008202730.130
chemical homeostasisGO:00488782920.127
multi organism reproductive processGO:00447032620.127
fatty acid metabolic processGO:0006631990.125
response to xenobiotic stimulusGO:0009410230.121
alpha amino acid metabolic processGO:1901605710.120
catenin import into nucleusGO:003541110.118
liver developmentGO:0001889900.117
sulfur compound metabolic processGO:0006790700.117
regulation of serine type endopeptidase activityGO:190000310.114
response to cytokineGO:00340972150.113
response to nutrient levelsGO:00316673700.112
regulation of secretion by cellGO:19035302080.111
localization of cellGO:00516742020.105
cellular response to nitrogen compoundGO:19016992100.104
reproductive processGO:00224143720.101
regulation of growthGO:00400081050.101
response to ketoneGO:19016541820.099
negative regulation of metabolic processGO:00098923310.095
macromolecule localizationGO:00330362520.093
regulation of multicellular organismal developmentGO:20000263760.093
organic acid biosynthetic processGO:0016053830.093
regulation of signal transductionGO:00099663180.092
protein homooligomerizationGO:0051260910.089
programmed cell deathGO:00125013920.089
cellular catabolic processGO:00442482950.088
organonitrogen compound biosynthetic processGO:19015661670.087
catabolic processGO:00090563510.086
female pregnancyGO:00075651220.086
response to bacteriumGO:00096172000.085
inflammatory responseGO:00069541500.085
oxidation reduction processGO:00551143040.085
response to molecule of bacterial originGO:00022371940.084
lipid biosynthetic processGO:00086101280.083
protein complex biogenesisGO:00702712630.083
positive regulation of signalingGO:00230562700.082
regulation of cellular component organizationGO:00511283680.082
response to estrogenGO:00436272320.082
cellular response to endogenous stimulusGO:00714953770.080
negative regulation of gene expressionGO:00106291990.078
negative regulation of cellular metabolic processGO:00313242810.078
cellular response to organonitrogen compoundGO:00714171970.078
regulation of rna metabolic processGO:00512523910.075
organic acid metabolic processGO:00060822920.075
organic substance catabolic processGO:19015753160.074
growthGO:00400071650.073
response to toxic substanceGO:00096361330.072
anatomical structure formation involved in morphogenesisGO:0048646830.071
hormone metabolic processGO:0042445690.068
regulation of anatomical structure morphogenesisGO:00226031410.067
small molecule biosynthetic processGO:00442831240.067
positive regulation of signal transductionGO:00099671750.067
lipid localizationGO:0010876620.066
intracellular signal transductionGO:00355563140.066
regulation of molecular functionGO:00650093980.066
positive regulation of cell differentiationGO:00455972170.065
negative regulation of biosynthetic processGO:00098901680.064
response to external biotic stimulusGO:00432072210.064
single organism biosynthetic processGO:00447113420.064
regulation of cell migrationGO:00303341280.063
response to inorganic substanceGO:00100353770.063
anatomical structure morphogenesisGO:00096532980.062
cellular homeostasisGO:00197252520.062
cellular lipid metabolic processGO:00442552080.060
tissue remodelingGO:0048771400.060
cellular component biogenesisGO:00440853680.060
mapk cascadeGO:00001651400.059
cellular response to oxygen containing compoundGO:19017013860.058
response to lipopolysaccharideGO:00324961910.057
cellular response to hormone stimulusGO:00328702470.057
circulatory system processGO:00030131830.056
regulation of ion transportGO:00432692450.055
cellular response to organic cyclic compoundGO:00714072020.055
organic anion transportGO:00157111320.055
angiotensin mediated drinking behaviorGO:000305120.055
blood vessel developmentGO:0001568690.054
negative regulation of cellular biosynthetic processGO:00313271610.054
organic hydroxy compound biosynthetic processGO:1901617510.054
behaviorGO:00076102050.053
cellular amino acid biosynthetic processGO:0008652320.053
organ regenerationGO:00311001010.053
regulation of catalytic activityGO:00507903040.053
positive regulation of extracellular matrix organizationGO:190305540.053
negative regulation of nucleic acid templated transcriptionGO:19035071170.053
response to triglycerideGO:003401430.052
multi multicellular organism processGO:00447061380.052
angiogenesisGO:0001525530.051
regulation of rna biosynthetic processGO:20011413810.051
secretionGO:00469033070.051
cell migrationGO:00164771970.050
protein phosphorylationGO:00064683450.050
gland developmentGO:00487321550.050
secretion by cellGO:00329402480.050
regulation of transcription dna templatedGO:00063553740.049
sulfur amino acid metabolic processGO:000009690.049
steroid biosynthetic processGO:0006694480.049
regulation of neurogenesisGO:00507672470.049
regulation of intracellular signal transductionGO:19025312180.049
thioester metabolic processGO:0035383280.049
negative regulation of macromolecule metabolic processGO:00106052600.049
extracellular matrix constituent secretionGO:007027840.048
regulation of system processGO:00440572080.048
regulation of reactive oxygen species biosynthetic processGO:190342650.048
regulation of hydrolase activityGO:00513361430.048
positive regulation of nervous system developmentGO:00519621780.048
muscle cell proliferationGO:0033002840.047
smooth muscle cell proliferationGO:0048659770.047
positive regulation of cellular biosynthetic processGO:00313282950.047
positive regulation of cell proliferationGO:00082842490.047
apoptotic processGO:00069153810.047
circulatory system developmentGO:00723591340.047
cellular chemical homeostasisGO:00550822470.046
protein oligomerizationGO:00512591910.046
cellular component assemblyGO:00226073600.046
cellular response to lipidGO:00713962010.044
single organism reproductive processGO:00447022970.044
vasculature developmentGO:0001944700.044
response to oxidative stressGO:00069791860.044
store operated calcium entryGO:000211520.044
homeostatic processGO:00425923310.044
defense responseGO:00069521940.043
artery smooth muscle contractionGO:001482440.043
limb morphogenesisGO:003510840.043
regulation of nervous system developmentGO:00519602640.043
macromolecular complex assemblyGO:00650032730.043
estrogen catabolic processGO:000671110.042
regulation of programmed cell deathGO:00430673410.041
locomotionGO:00400112370.041
regulation of phosphorus metabolic processGO:00511743490.041
positive regulation of molecular functionGO:00440932300.041
positive regulation of cell migrationGO:0030335960.041
protein localizationGO:00081041910.041
positive regulation of neurogenesisGO:00507691650.041
negative regulation of multicellular organismal processGO:00512412030.041
positive regulation of cell developmentGO:00107201760.041
heart morphogenesisGO:000300730.041
response to carbohydrateGO:00097431830.041
regulation of protein metabolic processGO:00512462890.041
response to oxygen levelsGO:00704822650.040
blood circulationGO:00080151830.040
positive regulation of nitrogen compound metabolic processGO:00511733340.040
transmission of nerve impulseGO:0019226420.040
regulation of cellular component movementGO:00512701500.039
regulation of extracellular matrix constituent secretionGO:000333020.039
positive regulation of catalytic activityGO:00430851840.039
tetrapyrrole metabolic processGO:0033013110.039
multicellular organism growthGO:003526410.039
nucleobase containing small molecule metabolic processGO:00550863160.039
heart developmentGO:0007507720.039
ion homeostasisGO:00508012120.038
brain developmentGO:00074202470.038
cellular ketone metabolic processGO:0042180510.038
negative regulation of cell proliferationGO:00082851190.038
response to hypoxiaGO:00016662310.038
carbohydrate derivative metabolic processGO:19011353460.038
positive regulation of intracellular signal transductionGO:19025331380.037
brain renin angiotensin systemGO:000203530.037
regulation of cell motilityGO:20001451310.036
regulation of cellular amino acid metabolic processGO:000652120.036
amine metabolic processGO:0009308380.036
regulation of neuron differentiationGO:00456642080.036
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.036
positive regulation of phosphorylationGO:00423271770.036
tube developmentGO:0035295890.036
cellular amine metabolic processGO:0044106380.035
embryonic appendage morphogenesisGO:003511340.035
negative regulation of macromolecule biosynthetic processGO:00105581480.035
regulation of hormone levelsGO:00108171870.035
renin angiotensin regulation of aldosterone productionGO:000201830.035
transmembrane transportGO:00550854120.035
regulation of blood vessel sizeGO:0050880890.035
regulation of cell differentiationGO:00455953200.035
response to insulinGO:00328681330.035
positive regulation of cellular component movementGO:00512721020.034
protein complex subunit organizationGO:00718223020.034
reactive oxygen species biosynthetic processGO:190340980.034
cell motilityGO:00488702020.034
tonic smooth muscle contractionGO:001482040.034
acylglycerol metabolic processGO:0006639210.034
macromolecular complex subunit organizationGO:00439333390.034
peptide transportGO:0015833970.033
response to methanolGO:003398610.033
sexual reproductionGO:00199531480.033
positive regulation of reactive oxygen species metabolic processGO:2000379160.033
cell morphogenesis involved in differentiationGO:00009041190.033
exogenous drug catabolic processGO:004273810.033
agingGO:00075682410.032
appendage morphogenesisGO:003510740.032
positive regulation of extracellular matrix constituent secretionGO:000333120.032
regulation of nucleic acid templated transcriptionGO:19035063800.032
response to decreased oxygen levelsGO:00362932370.032
response to hexoseGO:00097461440.032
reactive nitrogen species metabolic processGO:200105710.032
regulation of locomotionGO:00400121480.032
cardiovascular system developmentGO:00723581340.032
response to other organismGO:00517072200.031
positive regulation of biosynthetic processGO:00098913190.031
phenylpropanoid catabolic processGO:004627130.031
regulation of neuron projection developmentGO:00109751610.031
rna biosynthetic processGO:00327743800.031
response to monosaccharideGO:00342841590.031
negative regulation of nitrogen compound metabolic processGO:00511721610.031
organelle organizationGO:00069962660.030
positive regulation of locomotionGO:00400171020.030
central nervous system developmentGO:00074173110.030
positive regulation of cellular amine metabolic processGO:003324030.030
cellular component movementGO:00069282480.030
regulation of kinase activityGO:00435491170.030
alpha amino acid biosynthetic processGO:1901607230.030
positive regulation of developmental processGO:00510942830.029
response to metal ionGO:00100382530.029
positive regulation of neuron differentiationGO:00456661260.029
protein complex assemblyGO:00064612630.029
regulation of protein phosphorylationGO:00019321830.029
positive regulation of protein phosphorylationGO:00019341350.029
regulation of apoptotic processGO:00429813350.029
rna metabolic processGO:00160704060.028
aromatic compound catabolic processGO:00194391680.028
oligopeptide transportGO:000685740.028
regulation of cellular ketone metabolic processGO:0010565270.028
positive regulation of transcription factor import into nucleusGO:004299340.028
positive regulation of response to stimulusGO:00485842850.028
signal transduction by phosphorylationGO:00230141440.028
response to alkaloidGO:00432791320.028
positive regulation of cell motilityGO:2000147970.028
protein targeting to nucleusGO:0044744350.028
neuron projection developmentGO:00311752730.028
neuron differentiationGO:00301823680.027
immune system processGO:00023762040.027
regulation of cellular amine metabolic processGO:003323880.027
multicellular organism reproductionGO:00325042330.027
cellular response to stressGO:00335542690.027
regulation of homeostatic processGO:00328441010.027
developmental growthGO:00485891000.027
biological adhesionGO:00226101100.027
proteolysisGO:00065081750.027
carboxylic acid biosynthetic processGO:0046394830.026
organonitrogen compound catabolic processGO:19015651790.026
organic cyclic compound catabolic processGO:19013611750.026
ras protein signal transductionGO:0007265290.026
negative regulation of transcription dna templatedGO:00458921160.026
positive regulation of cell communicationGO:00106472710.026
triglyceride metabolic processGO:0006641210.026
single organism catabolic processGO:00447122830.026
response to transition metal nanoparticleGO:19902671220.026
positive regulation of phosphorus metabolic processGO:00105622620.026
response to muscle activity involved in regulation of muscle adaptationGO:001487320.026
neurological system processGO:00508772190.026
multicellular organismal reproductive processGO:00486092330.026
regulation of cell developmentGO:00602842630.026
lipid storageGO:001991510.025
regulation of phosphate metabolic processGO:00192203490.025
reproductive system developmentGO:00614581280.025
small molecule catabolic processGO:0044282590.025
transcription dna templatedGO:00063513770.025
positive regulation of programmed cell deathGO:00430681570.025
olfactory learningGO:000835510.025
fatty acid oxidationGO:0019395290.025
response to glucoseGO:00097491360.025
cellular response to steroid hormone stimulusGO:0071383930.025
regulation of angiogenesisGO:0045765390.025
regulation of anatomical structure sizeGO:00900661350.025
endothelium developmentGO:0003158120.025
neuron developmentGO:00486662860.024
cellular response to alcoholGO:0097306870.024
negative regulation of rna biosynthetic processGO:19026791180.024
cellular modified amino acid metabolic processGO:0006575610.024
response to insecticideGO:0017085210.024
cellular component morphogenesisGO:00329891550.024
regulation of endothelial cell differentiationGO:004560140.024
positive regulation of kinase activityGO:0033674770.024
regulation of reactive oxygen species metabolic processGO:2000377260.024
actin crosslink formationGO:005176430.024
positive regulation of reactive oxygen species biosynthetic processGO:190342820.024
single organism nuclear importGO:1902593350.023
nuclear importGO:0051170350.023
regulation of catabolic processGO:00098941130.023
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.023
peptidyl tyrosine modificationGO:0018212720.023
positive regulation of apoptotic processGO:00430651540.023
cellular response to corticosteroid stimulusGO:0071384690.023
negative regulation of developmental processGO:00510931250.023
response to chromateGO:004668730.023
cation homeostasisGO:00550801950.023
regulation of protein modification processGO:00313991940.023
cell growthGO:00160491040.023
mesoderm developmentGO:000749820.022
heterocycle catabolic processGO:00467001670.022
cell projection organizationGO:00300303020.022
organic hydroxy compound metabolic processGO:19016151150.022
acyl coa metabolic processGO:0006637280.022
blood vessel morphogenesisGO:0048514580.022
tissue developmentGO:00098882520.022
positive regulation of protein metabolic processGO:00512471780.021
negative regulation of molecular functionGO:00440921330.021
cell morphogenesisGO:00009021420.021
establishment of protein localizationGO:00451841410.021
regulation of secretionGO:00510462240.021
response to organophosphorusGO:00466831020.021
regulation of transferase activityGO:00513381230.021
regulation of neuron deathGO:19012141150.021
epithelial cell differentiationGO:0030855710.021
intestinal absorptionGO:005089230.021
regulation of ion homeostasisGO:2000021630.021
striated muscle tissue developmentGO:0014706580.021
protein localization to nucleusGO:0034504390.020
gamete generationGO:00072761240.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
acetyl coa metabolic processGO:0006084170.020
head developmentGO:00603222470.020
small gtpase mediated signal transductionGO:0007264360.020
lipid catabolic processGO:0016042460.020
cell part morphogenesisGO:00329901230.020
positive regulation of cell projection organizationGO:00313461110.020
positive regulation of phosphate metabolic processGO:00459372620.020
calcitriol biosynthetic process from calciolGO:003637820.020
reproductionGO:00000032450.020
organophosphate metabolic processGO:00196373700.020
negative regulation of transportGO:00510511360.020
renal system processGO:0003014400.019
maintenance of locationGO:0051235170.019
cellular ion homeostasisGO:00068731840.019
g protein coupled receptor signaling pathwayGO:00071862420.019
developmental process involved in reproductionGO:00030061590.019
toxin catabolic processGO:000940710.019
establishment of protein localization to organelleGO:0072594440.019
vasculogenesisGO:000157030.019
positive regulation of immune system processGO:0002684900.019
tolerance induction to nonself antigenGO:000246220.019
serine family amino acid metabolic processGO:0009069120.019
Human
cell adhesionGO:00071551100.019
response to fluorideGO:190261730.019
positive regulation of gene expressionGO:00106282440.019
naphthalene containing compound metabolic processGO:009042020.019
divalent metal ion transportGO:00708381320.019
embryonic limb morphogenesisGO:003032640.018
regulation of blood pressureGO:0008217830.018
alcohol metabolic processGO:0006066770.018
positive regulation of blood circulationGO:1903524650.018
regulation of cellular protein metabolic processGO:00322682670.018
cellular response to cytokine stimulusGO:00713451270.018
protein localization to organelleGO:0033365570.018
phenol containing compound biosynthetic processGO:004618990.018
nucleoside metabolic processGO:00091161790.018
regulation of cellular response to stressGO:0080135490.018
cellular cation homeostasisGO:00300031800.018
insecticide metabolic processGO:001714340.018
single organism cellular localizationGO:19025801020.018
regulation of lipid metabolic processGO:0019216680.018
cytoplasmic transportGO:00164821150.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
immune responseGO:00069551040.017
intracellular transportGO:00469071850.017
positive regulation of homeostatic processGO:0032846490.017
positive regulation of transferase activityGO:0051347810.017
regenerationGO:00310991630.017
glycosyl compound metabolic processGO:19016571820.017
response to testosteroneGO:0033574550.017
meiotic cell cycle processGO:190304630.017
positive regulation of protein modification processGO:00314011420.017
regulation of immune system processGO:00026821230.017
lauric acid metabolic processGO:004825240.017
regulation of vasculature developmentGO:1901342440.017
regulation of phosphorylationGO:00423252480.017
positive regulation of protein serine threonine kinase activityGO:0071902520.017
negative regulation of programmed cell deathGO:00430691830.017
purine ribonucleoside metabolic processGO:00461281680.017
negative regulation of cell deathGO:00605482290.016
acute phase responseGO:0006953200.016
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.016
regulation of plasma lipoprotein particle levelsGO:009700630.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
protein targetingGO:0006605610.016
lipid oxidationGO:0034440300.016
response to temperature stimulusGO:0009266940.016
regulation of body fluid levelsGO:0050878900.016
nitrogen compound transportGO:00717052290.016
muscle tissue developmentGO:0060537580.016
cation transportGO:00068123820.016
negative regulation of rna metabolic processGO:00512531230.016
negative regulation of cell differentiationGO:0045596990.016
olfactory behaviorGO:004204820.016
organ growthGO:0035265240.016
vitamin transportGO:0051180140.016
response to interleukin 1GO:0070555550.016
sulfur compound biosynthetic processGO:0044272190.016
positive regulation of hydrolase activityGO:0051345860.016
regulation of alpha beta t cell activationGO:004663420.016
bile acid biosynthetic processGO:000669930.016
positive regulation of protein kinase activityGO:0045860730.016
protein import into nucleusGO:0006606350.016
reproductive structure developmentGO:00486081280.016
response to vitamin dGO:0033280340.016
regulation of synaptic plasticityGO:0048167700.016
vesicle mediated transportGO:00161921810.016
neutral lipid metabolic processGO:0006638210.015
positive regulation of protein kinase b signalingGO:0051897100.015
regulation of stem cell differentiationGO:200073620.015
organic acid catabolic processGO:0016054490.015
chlorinated hydrocarbon metabolic processGO:004219640.015
positive regulation of immunoglobulin productionGO:000263940.015
muscle cell differentiationGO:0042692520.015
regulation of cellular catabolic processGO:00313291010.015
cytokine biosynthetic processGO:004208930.015
response to activityGO:0014823730.015
peptide hormone secretionGO:0030072840.015
regulation of systemic arterial blood pressureGO:0003073300.015
negative regulation of cell developmentGO:0010721820.015
peptidyl tyrosine phosphorylationGO:0018108720.015
cardiac muscle tissue developmentGO:0048738260.015
negative regulation of apoptotic processGO:00430661810.015
chemosensory behaviorGO:000763520.015
response to biotic stimulusGO:00096072260.015
exocytosisGO:0006887600.015
gastrulationGO:000736920.015
negative regulation of nervous system developmentGO:0051961790.015
regulation of smooth muscle cell proliferationGO:0048660750.015
vascular process in circulatory systemGO:0003018960.015
maternal process involved in female pregnancyGO:0060135380.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
positive regulation of tolerance inductionGO:000264510.015
regulation of protein serine threonine kinase activityGO:0071900640.015
positive regulation of transcription dna templatedGO:00458931970.015
positive regulation of cell deathGO:00109421840.014
regulation of synaptic transmissionGO:00508041410.014
negative regulation of catalytic activityGO:00430861030.014
response to estradiolGO:00323551640.014
male gamete generationGO:0048232990.014
cell cycle processGO:0022402570.014
cell cell signalingGO:00072673350.014
ribonucleotide metabolic processGO:00092592310.014
single organism carbohydrate metabolic processGO:00447231180.014
spermatogenesisGO:0007283990.014
neuron projection morphogenesisGO:00488121220.014
positive regulation of cellular component organizationGO:00511302000.014
cell cycleGO:00070491010.014
monocarboxylic acid biosynthetic processGO:0072330480.014
neuronal action potentialGO:0019228350.014
ribonucleoside metabolic processGO:00091191740.014
formation of primary germ layerGO:000170410.014
cellular response to peptide hormone stimulusGO:00713751200.014
response to vitamin b6GO:003451610.014
purine nucleoside metabolic processGO:00422781690.014
porphyrin containing compound metabolic processGO:000677880.014
nucleocytoplasmic transportGO:0006913480.014
stress activated protein kinase signaling cascadeGO:0031098370.014
response to vitamin aGO:0033189360.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
lipid transportGO:0006869610.013
regulation of cellular localizationGO:00603412630.013
divalent inorganic cation transportGO:00725111340.013
positive regulation of lipid metabolic processGO:0045834330.013
bmp signaling pathwayGO:003050940.013
response to increased oxygen levelsGO:0036296450.013
defense response to gram negative bacteriumGO:005082930.013
nucleic acid templated transcriptionGO:00976593790.013
organic hydroxy compound transportGO:0015850770.013
forebrain developmentGO:0030900980.013
modified amino acid transportGO:0072337120.013
cytokine productionGO:0001816610.013
positive regulation of transportGO:00510502450.013
respiratory system developmentGO:0060541450.013
cell projection assemblyGO:0030031210.013
cellular response to hexose stimulusGO:0071331650.013
regulation of cell projection organizationGO:00313441750.013

Dmgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
vascular diseaseDOID:17800.050
artery diseaseDOID:005082800.050
essential hypertensionDOID:1082500.050
hypertensionDOID:1076300.050
disease of anatomical entityDOID:700.050
cardiovascular system diseaseDOID:128700.050
disease of metabolismDOID:001466700.024
inherited metabolic disorderDOID:65500.024
connective tissue diseaseDOID:6500.015
musculoskeletal system diseaseDOID:1700.015