Rattus norvegicus

275 known processes

Igf1

insulin-like growth factor 1

Igf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to peptideGO:19016522920.342
Rat
cation transportGO:00068123820.246
cellular component movementGO:00069282480.187
homeostatic processGO:00425923310.166
Mouse
growthGO:00400071650.139
regulation of cellular component organizationGO:00511283680.138
positive regulation of developmental processGO:00510942830.136
response to other organismGO:00517072200.134
immune responseGO:00069551040.134
cellular component assemblyGO:00226073600.132
cellular response to hormone stimulusGO:00328702470.131
positive regulation of response to stimulusGO:00485842850.128
positive regulation of cell differentiationGO:00455972170.122
regulation of cell growthGO:0001558850.118
anatomical structure morphogenesisGO:00096532980.114
Mouse
response to oxygen levelsGO:00704822650.106
apoptotic processGO:00069153810.105
response to peptide hormoneGO:00434342780.103
Rat
cellular response to oxygen containing compoundGO:19017013860.101
positive regulation of axon guidanceGO:190266930.098
response to decreased oxygen levelsGO:00362932370.098
positive regulation of multicellular organismal processGO:00512403870.090
response to estradiolGO:00323551640.090
Rat
neuron differentiationGO:00301823680.087
defense responseGO:00069521940.086
positive regulation of immune system processGO:0002684900.086
reproductive processGO:00224143720.086
positive regulation of locomotionGO:00400171020.082
cell motilityGO:00488702020.081
carbohydrate derivative metabolic processGO:19011353460.081
Mouse
cellular response to nitrogen compoundGO:19016992100.079
locomotionGO:00400112370.079
cellular ion homeostasisGO:00068731840.079
cellular homeostasisGO:00197252520.079
urogenital system developmentGO:0001655780.078
Mouse
positive regulation of transportGO:00510502450.077
regulation of cell differentiationGO:00455953200.077
cytosolic calcium ion homeostasisGO:00514801400.075
blood vessel developmentGO:0001568690.075
cellular calcium ion homeostasisGO:00068741600.074
negative regulation of signalingGO:00230571570.074
cardiovascular system developmentGO:00723581340.073
Mouse
response to extracellular stimulusGO:00099913800.072
regulation of cell developmentGO:00602842630.070
positive regulation of cellular component organizationGO:00511302000.069
circulatory system developmentGO:00723591340.068
Mouse
response to insulinGO:00328681330.068
chemical homeostasisGO:00488782920.068
Mouse
cell projection organizationGO:00300303020.067
cellular response to organonitrogen compoundGO:00714171970.067
inflammatory responseGO:00069541500.066
localization of cellGO:00516742020.065
regulation of secretionGO:00510462240.064
regulation of ion transportGO:00432692450.063
response to dexamethasoneGO:0071548490.063
cellular response to peptide hormone stimulusGO:00713751200.063
negative regulation of cell deathGO:00605482290.062
response to mechanical stimulusGO:00096121340.062
response to corticosteroidGO:00319602350.062
regulation of apoptotic processGO:00429813350.061
regulation of behaviorGO:0050795610.061
cellular cation homeostasisGO:00300031800.060
epithelial cell proliferationGO:0050673540.060
intracellular signal transductionGO:00355563140.059
oxoacid metabolic processGO:00434362900.059
Mouse
divalent metal ion transportGO:00708381320.059
negative regulation of response to stimulusGO:00485851550.058
divalent inorganic cation homeostasisGO:00725071650.057
positive regulation of cytosolic calcium ion concentrationGO:00072041220.056
response to estrogenGO:00436272320.056
Rat
response to glucocorticoidGO:00513842230.054
regulation of growthGO:00400081050.053
cellular lipid metabolic processGO:00442552080.053
blood circulationGO:00080151830.052
cellular response to endogenous stimulusGO:00714953770.052
response to external biotic stimulusGO:00432072210.051
chemotaxisGO:0006935660.051
taxisGO:0042330670.051
secretion by cellGO:00329402480.051
cellular chemical homeostasisGO:00550822470.050
cellular response to insulin stimulusGO:0032869810.050
programmed cell deathGO:00125013920.050
positive regulation of cellular component movementGO:00512721020.049
cell growthGO:00160491040.049
tube developmentGO:0035295890.048
Mouse
response to woundingGO:00096112540.048
Rat
renal system developmentGO:0072001670.048
rna metabolic processGO:00160704060.048
Mouse
regulation of locomotionGO:00400121480.047
metal ion transportGO:00300012890.047
positive regulation of cell projection organizationGO:00313461110.047
ion homeostasisGO:00508012120.047
regulation of multicellular organismal developmentGO:20000263760.044
Mouse
neuron projection developmentGO:00311752730.044
regulation of cell migrationGO:00303341280.044
regulation of response to external stimulusGO:00321011060.043
positive regulation of secretionGO:00510471400.043
regulation of system processGO:00440572080.043
regulation of neuron differentiationGO:00456642080.043
regulation of metal ion transportGO:00109591180.043
tissue developmentGO:00098882520.043
Mouse
nucleobase containing small molecule metabolic processGO:00550863160.042
regenerationGO:00310991630.042
regulation of cell motilityGO:20001451310.042
cellular metal ion homeostasisGO:00068751720.042
regulation of nervous system developmentGO:00519602640.042
Mouse
response to carbohydrateGO:00097431830.041
regulation of protein metabolic processGO:00512462890.041
regulation of programmed cell deathGO:00430673410.041
nitrogen compound transportGO:00717052290.040
regulation of neurogenesisGO:00507672470.040
response to hypoxiaGO:00016662310.040
divalent inorganic cation transportGO:00725111340.040
regulation of leukocyte migrationGO:0002685240.040
calcium ion transportGO:00068161310.039
embryonic skeletal system developmentGO:004870630.039
neuron developmentGO:00486662860.039
positive regulation of neuron differentiationGO:00456661260.039
response to inorganic substanceGO:00100353770.039
regulation of rna metabolic processGO:00512523910.039
Mouse
macromolecule localizationGO:00330362520.039
regulation of homeostatic processGO:00328441010.038
negative regulation of programmed cell deathGO:00430691830.037
positive regulation of neurogenesisGO:00507691650.037
regulation of catalytic activityGO:00507903040.037
agingGO:00075682410.037
axon extension involved in axon guidanceGO:004884660.037
response to nutrientGO:00075842480.037
positive regulation of cell motilityGO:2000147970.036
cellular response to peptideGO:19016531330.036
macromolecular complex subunit organizationGO:00439333390.036
positive regulation of signalingGO:00230562700.036
response to heatGO:0009408600.036
positive regulation of cell communicationGO:00106472710.035
regulation of cellular component movementGO:00512701500.035
regulation of cellular localizationGO:00603412630.034
regulation of epithelial cell proliferationGO:0050678490.034
response to cytokineGO:00340972150.034
Rat
positive regulation of cell developmentGO:00107201760.034
gland developmentGO:00487321550.034
Mouse
carboxylic acid metabolic processGO:00197522890.034
positive regulation of nitrogen compound metabolic processGO:00511733340.034
Mouse
organ regenerationGO:00311001010.034
enzyme linked receptor protein signaling pathwayGO:00071671160.034
cellular divalent inorganic cation homeostasisGO:00725031620.033
camp metabolic processGO:0046058630.033
calcium ion homeostasisGO:00550741620.033
response to vitaminGO:00332731310.033
central nervous system developmentGO:00074173110.033
Mouse
developmental growthGO:00485891000.033
Mouse
cellular amine metabolic processGO:0044106380.032
ossificationGO:0001503700.032
regulation of axon extensionGO:0030516240.032
insulin like growth factor receptor signaling pathwayGO:004800930.031
response to glucoseGO:00097491360.031
response to metal ionGO:00100382530.031
regulation of chemotaxisGO:0050920290.031
embryonic skeletal system morphogenesisGO:004870430.031
cation homeostasisGO:00550801950.031
cellular amino acid metabolic processGO:00065201070.031
cellular response to cytokine stimulusGO:00713451270.031
regulation of molecular functionGO:00650093980.031
negative regulation of metabolic processGO:00098923310.031
positive regulation of axon extension involved in axon guidanceGO:004884230.030
regulation of blood pressureGO:0008217830.030
immune system processGO:00023762040.030
multi organism reproductive processGO:00447032620.030
negative regulation of cell communicationGO:00106481580.030
positive regulation of intracellular signal transductionGO:19025331380.029
response to nutrient levelsGO:00316673700.029
metal ion homeostasisGO:00550651860.029
sequestering of metal ionGO:005123890.029
positive regulation of cell migrationGO:0030335960.029
maintenance of locationGO:0051235170.028
cell morphogenesis involved in differentiationGO:00009041190.028
single organism intracellular transportGO:19025821660.028
response to biotic stimulusGO:00096072260.028
regulation of hormone levelsGO:00108171870.028
small gtpase mediated signal transductionGO:0007264360.028
developmental growth involved in morphogenesisGO:0060560330.027
cellular response to organic cyclic compoundGO:00714072020.027
regulation of signal transductionGO:00099663180.027
multicellular organismal reproductive processGO:00486092330.027
Zebrafish
protein complex biogenesisGO:00702712630.027
response to ketoneGO:19016541820.027
cellular component biogenesisGO:00440853680.027
regulation of cell proliferationGO:00421273590.027
positive regulation of neuron projection developmentGO:0010976990.027
cellular catabolic processGO:00442482950.027
protein complex subunit organizationGO:00718223020.027
single organism catabolic processGO:00447122830.026
brain developmentGO:00074202470.026
Mouse
sex differentiationGO:00075481130.026
single organism behaviorGO:00447081300.026
response to hexoseGO:00097461440.026
hormone metabolic processGO:0042445690.026
purine nucleotide metabolic processGO:00061632290.026
response to monosaccharideGO:00342841590.026
rna biosynthetic processGO:00327743800.025
Mouse
proteolysisGO:00065081750.025
positive regulation of cell proliferationGO:00082842490.025
Mouse
regulation of cell projection organizationGO:00313441750.025
regulation of extent of cell growthGO:0061387250.025
regulation of secretion by cellGO:19035302080.025
reproductive system developmentGO:00614581280.025
Mouse
positive regulation of molecular functionGO:00440932300.025
nucleic acid templated transcriptionGO:00976593790.025
Mouse
positive regulation of chemotaxisGO:0050921230.025
ribonucleotide metabolic processGO:00092592310.025
purine containing compound metabolic processGO:00725212530.025
organic hydroxy compound metabolic processGO:19016151150.025
regulation of neuron projection developmentGO:00109751610.025
ribose phosphate metabolic processGO:00196932350.024
response to campGO:0051591910.024
Rat
positive regulation of phosphorylationGO:00423271770.024
positive regulation of nervous system developmentGO:00519621780.024
Mouse
positive regulation of phosphate metabolic processGO:00459372620.024
cell migrationGO:00164771970.024
positive regulation of ion transportGO:0043270940.024
reproductionGO:00000032450.024
Zebrafish
organic cyclic compound catabolic processGO:19013611750.024
anion transportGO:00068201780.023
response to acid chemicalGO:00011012220.023
anatomical structure formation involved in morphogenesisGO:0048646830.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
ras protein signal transductionGO:0007265290.023
amine metabolic processGO:0009308380.023
anterior posterior pattern specificationGO:000995210.023
secretionGO:00469033070.023
transcription dna templatedGO:00063513770.022
Mouse
organ morphogenesisGO:0009887750.022
Mouse
cellular response to corticosteroid stimulusGO:0071384690.022
nucleoside phosphate metabolic processGO:00067532830.022
organic hydroxy compound transportGO:0015850770.022
negative regulation of gene expressionGO:00106291990.022
regulation of amine transportGO:0051952540.022
regulation of anatomical structure morphogenesisGO:00226031410.022
response to radiationGO:00093141370.022
Rat
cell cell signalingGO:00072673350.021
positive regulation of gene expressionGO:00106282440.021
Mouse
organonitrogen compound catabolic processGO:19015651790.021
regulation of calcium ion transportGO:0051924770.021
cyclic nucleotide metabolic processGO:0009187800.021
complement activationGO:0006956110.021
cytoplasmic transportGO:00164821150.021
wound healingGO:00420601220.021
Rat
organelle organizationGO:00069962660.021
Mouse
formation of primary germ layerGO:000170410.021
negative regulation of apoptotic processGO:00430661810.021
positive regulation of catalytic activityGO:00430851840.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
Mouse
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
Mouse
regulation of purine nucleotide metabolic processGO:19005421150.020
positive regulation of epithelial cell proliferationGO:0050679320.020
negative regulation of homeostatic processGO:0032845470.020
skeletal system developmentGO:0001501410.020
response to bacteriumGO:00096172000.020
cellular response to lipidGO:00713962010.020
negative regulation of transportGO:00510511360.020
cognitionGO:0050890920.020
single organism biosynthetic processGO:00447113420.020
regulation of anatomical structure sizeGO:00900661350.020
angiogenesisGO:0001525530.020
intracellular transportGO:00469071850.020
positive regulation of programmed cell deathGO:00430681570.019
single organism carbohydrate metabolic processGO:00447231180.019
neuron projection extensionGO:1990138260.019
negative regulation of macromolecule metabolic processGO:00106052600.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.019
adult locomotory behaviorGO:000834440.019
regulation of rna biosynthetic processGO:20011413810.019
Mouse
lipid metabolic processGO:00066292830.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
Mouse
embryonic organ morphogenesisGO:004856250.019
hormone transportGO:00099141210.019
positive regulation of transcription dna templatedGO:00458931970.018
Mouse
protein complex assemblyGO:00064612630.018
vasculature developmentGO:0001944700.018
Mouse
macromolecular complex assemblyGO:00650032730.018
cellular response to growth factor stimulusGO:00713631620.018
negative regulation of signal transductionGO:0009968830.018
regulation of intracellular signal transductionGO:19025312180.018
mesonephros developmentGO:0001823140.018
response to growth factorGO:00708481890.018
cell morphogenesisGO:00009021420.018
positive regulation of secretion by cellGO:19035321280.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
Mouse
neuron projection morphogenesisGO:00488121220.018
circulatory system processGO:00030131830.018
positive regulation of cell growthGO:0030307440.018
regulation of cellular protein metabolic processGO:00322682670.018
cellular response to alcoholGO:0097306870.018
ribose phosphate biosynthetic processGO:0046390870.017
carbohydrate derivative biosynthetic processGO:19011371240.017
Mouse
axonogenesisGO:0007409710.017
neurological system processGO:00508772190.017
positive regulation of cell deathGO:00109421840.017
immune system developmentGO:0002520410.017
vesicle mediated transportGO:00161921810.017
cytosolic calcium ion transportGO:0060401390.017
rhythmic processGO:00485111560.017
Mouse
single organism reproductive processGO:00447022970.017
Zebrafish Mouse
regulation of phosphorus metabolic processGO:00511743490.017
head developmentGO:00603222470.017
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
cell part morphogenesisGO:00329901230.017
regulation of cell morphogenesisGO:0022604770.017
heart developmentGO:0007507720.017
response to transition metal nanoparticleGO:19902671220.017
catabolic processGO:00090563510.017
regulation of cellular amine metabolic processGO:003323880.017
learning or memoryGO:0007611900.016
organonitrogen compound biosynthetic processGO:19015661670.016
Mouse
negative regulation of cellular protein metabolic processGO:00322691060.016
positive regulation of cellular biosynthetic processGO:00313282950.016
forebrain developmentGO:0030900980.016
heterocycle catabolic processGO:00467001670.016
fibrinolysisGO:004273020.016
sequestering of calcium ionGO:005120880.016
cellular response to glucocorticoid stimulusGO:0071385680.016
regulation of developmental growthGO:0048638450.016
regulation of hydrolase activityGO:00513361430.016
sensory organ developmentGO:0007423740.016
Mouse
response to organophosphorusGO:00466831020.015
Rat
liver developmentGO:0001889900.015
positive regulation of rna biosynthetic processGO:19026801970.015
Mouse
protein processingGO:0016485680.015
response to alkaloidGO:00432791320.015
Rat
carbohydrate homeostasisGO:0033500750.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.015
nucleobase containing compound catabolic processGO:00346551520.015
regulation of phosphorylationGO:00423252480.015
mapk cascadeGO:00001651400.015
Mouse
cell projection morphogenesisGO:00488581230.015
amine transportGO:0015837570.015
glucose homeostasisGO:0042593750.015
phenol containing compound metabolic processGO:0018958300.015
nucleotide biosynthetic processGO:0009165980.015
nucleotide metabolic processGO:00091172790.015
actin cytoskeleton organizationGO:0030036730.015
response to temperature stimulusGO:0009266940.015
ribonucleoside metabolic processGO:00091191740.015
lipid localizationGO:0010876620.014
protein secretionGO:0009306340.014
ion transmembrane transportGO:00342203650.014
positive regulation of hydrolase activityGO:0051345860.014
positive regulation of response to external stimulusGO:0032103510.014
gastrulationGO:000736920.014
multicellular organism reproductionGO:00325042330.014
Zebrafish
axon extensionGO:0048675260.014
response to transforming growth factor betaGO:0071559460.014
organic substance catabolic processGO:19015753160.014
response to toxic substanceGO:00096361330.014
positive regulation of behaviorGO:0048520380.014
cell type specific apoptotic processGO:00972851340.014
multicellular organism growthGO:003526410.014
Mouse
protein kinase c activating g protein coupled receptor signaling pathwayGO:0007205120.014
renin secretion into blood streamGO:000200110.014
motor neuron axon guidanceGO:000804510.014
behaviorGO:00076102050.014
female sex differentiationGO:0046660590.013
embryonic pattern specificationGO:000988010.013
cellular response to dexamethasone stimulusGO:0071549360.013
kidney developmentGO:0001822670.013
cellular response to external stimulusGO:00714961180.013
Rat
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.013
regulation of vesicle mediated transportGO:0060627810.013
cellular response to stressGO:00335542690.013
gamete generationGO:00072761240.013
Zebrafish
single organism organelle organizationGO:19025891800.013
organic acid metabolic processGO:00060822920.013
Mouse
heart morphogenesisGO:000300730.013
regulation of cellular ketone metabolic processGO:0010565270.013
axon developmentGO:0061564960.013
vascular process in circulatory systemGO:0003018960.013
regulation of myeloid cell differentiationGO:0045637120.013
rho protein signal transductionGO:0007266110.013
embryonic cranial skeleton morphogenesisGO:004870120.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
multi multicellular organism processGO:00447061380.013
bmp signaling pathwayGO:003050940.013
aromatic compound catabolic processGO:00194391680.013
sexual reproductionGO:00199531480.013
Zebrafish
artery developmentGO:006084030.013
salivary gland developmentGO:000743130.013
regulation of peptide hormone secretionGO:0090276800.013
development of primary sexual characteristicsGO:00451371070.013
carbohydrate metabolic processGO:00059751300.013
regulation of angiogenesisGO:0045765390.013
regulation of peptide transportGO:0090087870.013
leukocyte migrationGO:0050900380.013
regulation of ion homeostasisGO:2000021630.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
regulation of phosphate metabolic processGO:00192203490.012
negative regulation of cellular metabolic processGO:00313242810.012
cellular response to hexose stimulusGO:0071331650.012
lung developmentGO:0030324430.012
Mouse
positive regulation of protein modification processGO:00314011420.012
immune effector processGO:0002252530.012
positive regulation of cellular amine metabolic processGO:003324030.012
protein oligomerizationGO:00512591910.012
cell chemotaxisGO:0060326310.012
organic anion transportGO:00157111320.012
cellular response to transforming growth factor beta stimulusGO:0071560410.012
positive regulation of signal transductionGO:00099671750.012
male sex differentiationGO:0046661640.012
organic acid transportGO:00158491160.012
isoprenoid metabolic processGO:0006720450.012
glycosyl compound catabolic processGO:19016581260.012
sulfur compound metabolic processGO:0006790700.012
Mouse
negative regulation of developmental processGO:00510931250.012
positive regulation of rna metabolic processGO:00512542030.012
Mouse
negative regulation of molecular functionGO:00440921330.012
leukocyte activationGO:0045321760.012
negative regulation of protein metabolic processGO:00512481140.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
carbohydrate derivative catabolic processGO:19011361470.012
regulation of hormone secretionGO:00468831060.012
lipid storageGO:001991510.012
cellular response to steroid hormone stimulusGO:0071383930.011
regulation of axonogenesisGO:0050770370.011
protein maturationGO:0051604680.011
regulation of release of sequestered calcium ion into cytosolGO:0051279180.011
brain renin angiotensin systemGO:000203530.011
neuron deathGO:00709971270.011
response to oxidative stressGO:00069791860.011
reproductive structure developmentGO:00486081280.011
Mouse
g protein coupled receptor signaling pathwayGO:00071862420.011
nucleoside phosphate biosynthetic processGO:19012931020.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
regulation of organelle organizationGO:0033043800.011
Mouse
response to ethanolGO:00454711620.011
Rat
connective tissue developmentGO:0061448330.011
Mouse
organophosphate metabolic processGO:00196373700.011
male gonad developmentGO:0008584590.011
development of primary male sexual characteristicsGO:0046546590.011
regulation of endothelial cell proliferationGO:0001936180.011
ovulation cycleGO:0042698670.011
ear developmentGO:0043583210.011
Mouse
inner ear developmentGO:0048839210.011
Mouse
regulation of response to stressGO:00801341260.011
smooth muscle cell proliferationGO:0048659770.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
epithelial cell migrationGO:0010631190.011
cellular response to carbohydrate stimulusGO:0071322720.011
response to cobalt ionGO:0032025120.010
gonad developmentGO:00084061040.010
positive regulation of protein metabolic processGO:00512471780.010
peptidyl amino acid modificationGO:00181931260.010
cellular ketone metabolic processGO:0042180510.010
carboxylic acid transportGO:00469421150.010
cellular response to ketoneGO:1901655510.010
memoryGO:0007613540.010
cellular response to monosaccharide stimulusGO:0071326670.010
purine containing compound biosynthetic processGO:0072522850.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010
Mouse
cellular response to glucose stimulusGO:0071333650.010
positive regulation of apoptotic processGO:00430651540.010
positive regulation of axon extensionGO:0045773140.010
renal system processGO:0003014400.010
regulation of transmembrane transportGO:00347621220.010
regulation of cellular amino acid metabolic processGO:000652120.010
release of sequestered calcium ion into cytosolGO:0051209250.010
actin filament based processGO:0030029860.010

Igf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.061
disease of anatomical entityDOID:700.061
connective tissue diseaseDOID:6500.061
disease of metabolismDOID:001466700.057
cardiovascular system diseaseDOID:128700.036
artery diseaseDOID:005082800.036
vascular diseaseDOID:17800.036
inherited metabolic disorderDOID:65500.035
eye and adnexa diseaseDOID:149200.030
eye diseaseDOID:561400.030
sensory system diseaseDOID:005015500.030
nervous system diseaseDOID:86300.030
bone diseaseDOID:008000100.016
bone development diseaseDOID:008000600.016
hypertensionDOID:1076300.011
retinal degenerationDOID:846600.011
retinal diseaseDOID:567900.011