Rattus norvegicus

132 known processes

Srf

serum response factor (c-fos serum response element-binding transcription factor)

(Aliases: RGD1559787)

Srf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.124
regulation of rna biosynthetic processGO:20011413810.116
nucleic acid templated transcriptionGO:00976593790.116
regulation of transcription dna templatedGO:00063553740.112
regulation of nucleic acid templated transcriptionGO:19035063800.104
positive regulation of transcription dna templatedGO:00458931970.096
regulation of molecular functionGO:00650093980.078
Human
rna biosynthetic processGO:00327743800.078
regulation of transcription from rna polymerase ii promoterGO:00063572340.074
Human
rna metabolic processGO:00160704060.073
positive regulation of rna biosynthetic processGO:19026801970.071
response to extracellular stimulusGO:00099913800.065
positive regulation of cell proliferationGO:00082842490.060
central nervous system developmentGO:00074173110.059
positive regulation of gene expressionGO:00106282440.059
positive regulation of nitrogen compound metabolic processGO:00511733340.057
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.056
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.055
positive regulation of nucleobase containing compound metabolic processGO:00459353190.053
transcription from rna polymerase ii promoterGO:00063662520.052
Human
regulation of rna metabolic processGO:00512523910.052
positive regulation of biosynthetic processGO:00098913190.050
transcription dna templatedGO:00063513770.049
positive regulation of cellular biosynthetic processGO:00313282950.046
chemical homeostasisGO:00488782920.044
single organism organelle organizationGO:19025891800.043
programmed cell deathGO:00125013920.042
anatomical structure morphogenesisGO:00096532980.041
Human
regulation of neurogenesisGO:00507672470.041
regulation of apoptotic processGO:00429813350.040
locomotionGO:00400112370.040
regulation of phosphorus metabolic processGO:00511743490.040
positive regulation of rna metabolic processGO:00512542030.039
protein localizationGO:00081041910.038
negative regulation of cell deathGO:00605482290.038
regulation of neuron differentiationGO:00456642080.038
regulation of cell projection organizationGO:00313441750.038
positive regulation of nucleic acid templated transcriptionGO:19035081970.038
response to inorganic substanceGO:00100353770.037
defense responseGO:00069521940.036
cellular response to stressGO:00335542690.036
Human
response to nutrient levelsGO:00316673700.036
neuron deathGO:00709971270.036
regulation of secretion by cellGO:19035302080.035
regulation of programmed cell deathGO:00430673410.035
protein complex subunit organizationGO:00718223020.035
Human
neuron developmentGO:00486662860.035
secretionGO:00469033070.034
regulation of cellular component organizationGO:00511283680.034
Human
cellular chemical homeostasisGO:00550822470.034
purine containing compound metabolic processGO:00725212530.033
tissue developmentGO:00098882520.032
regulation of signal transductionGO:00099663180.032
organelle organizationGO:00069962660.032
intracellular signal transductionGO:00355563140.032
cellular response to oxygen containing compoundGO:19017013860.032
regulation of phosphate metabolic processGO:00192203490.031
neuron differentiationGO:00301823680.031
negative regulation of nitrogen compound metabolic processGO:00511721610.031
negative regulation of macromolecule metabolic processGO:00106052600.031
regulation of nervous system developmentGO:00519602640.031
regulation of catalytic activityGO:00507903040.031
regulation of cellular ketone metabolic processGO:0010565270.031
regulation of neuron projection developmentGO:00109751610.031
negative regulation of cellular metabolic processGO:00313242810.030
apoptotic processGO:00069153810.030
regulation of ion transportGO:00432692450.030
negative regulation of macromolecule biosynthetic processGO:00105581480.029
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.029
positive regulation of molecular functionGO:00440932300.028
Human
cellular ketone metabolic processGO:0042180510.028
response to metal ionGO:00100382530.028
nucleotide metabolic processGO:00091172790.028
response to acid chemicalGO:00011012220.028
inorganic cation transmembrane transportGO:00986622020.028
regulation of hydrolase activityGO:00513361430.028
regulation of multicellular organismal developmentGO:20000263760.028
positive regulation of cell deathGO:00109421840.027
cardiac ventricle developmentGO:000323110.027
secretion by cellGO:00329402480.027
response to ketoneGO:19016541820.027
response to oxygen levelsGO:00704822650.027
Human
regulation of cell developmentGO:00602842630.027
organic acid metabolic processGO:00060822920.026
positive regulation of transportGO:00510502450.026
cellular amine metabolic processGO:0044106380.026
positive regulation of cellular component organizationGO:00511302000.026
Human
negative regulation of metabolic processGO:00098923310.026
carboxylic acid metabolic processGO:00197522890.026
response to decreased oxygen levelsGO:00362932370.025
Human
positive regulation of signalingGO:00230562700.025
regulation of cellular amino acid metabolic processGO:000652120.025
cell projection organizationGO:00300303020.025
regulation of response to external stimulusGO:00321011060.025
heart morphogenesisGO:000300730.025
oxidation reduction processGO:00551143040.025
vesicle mediated transportGO:00161921810.024
response to peptide hormoneGO:00434342780.024
brain developmentGO:00074202470.024
cellular homeostasisGO:00197252520.023
cellular response to external stimulusGO:00714961180.023
response to ethanolGO:00454711620.023
response to woundingGO:00096112540.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
cellular catabolic processGO:00442482950.023
negative regulation of biosynthetic processGO:00098901680.022
negative regulation of signalingGO:00230571570.022
monovalent inorganic cation transportGO:00156721720.022
metal ion transportGO:00300012890.022
regulation of cell differentiationGO:00455953200.022
Human
regulation of response to stressGO:00801341260.022
ribose phosphate metabolic processGO:00196932350.022
response to radiationGO:00093141370.022
cellular nitrogen compound catabolic processGO:00442701630.022
head developmentGO:00603222470.022
actin filament based processGO:0030029860.021
circulatory system developmentGO:00723591340.021
Human
muscle structure developmentGO:0061061870.021
Human
cation transportGO:00068123820.021
cellular component assemblyGO:00226073600.021
Human
response to hypoxiaGO:00016662310.021
Human
nucleobase containing small molecule metabolic processGO:00550863160.021
behaviorGO:00076102050.021
oxoacid metabolic processGO:00434362900.021
cellular component biogenesisGO:00440853680.021
Human
regulation of protein transportGO:0051223680.021
positive regulation of multicellular organismal processGO:00512403870.021
Human
negative regulation of apoptotic processGO:00430661810.021
cellular amino acid metabolic processGO:00065201070.020
protein phosphorylationGO:00064683450.020
response to peptideGO:19016522920.020
amine metabolic processGO:0009308380.020
positive regulation of transcription factor import into nucleusGO:004299340.020
actin cytoskeleton organizationGO:0030036730.020
small gtpase mediated signal transductionGO:0007264360.020
ribonucleotide metabolic processGO:00092592310.020
peptidyl amino acid modificationGO:00181931260.020
negative regulation of rna biosynthetic processGO:19026791180.020
cellular component morphogenesisGO:00329891550.020
positive regulation of cell communicationGO:00106472710.020
regulation of cellular localizationGO:00603412630.019
catabolic processGO:00090563510.019
macromolecular complex subunit organizationGO:00439333390.019
Human
regulation of nucleotide metabolic processGO:00061401170.019
cation homeostasisGO:00550801950.019
purine nucleotide metabolic processGO:00061632290.019
inflammatory responseGO:00069541500.019
cellular response to endogenous stimulusGO:00714953770.019
circulatory system processGO:00030131830.019
dna integrity checkpointGO:003157020.019
negative regulation of programmed cell deathGO:00430691830.019
nucleoside metabolic processGO:00091161790.019
heterocycle catabolic processGO:00467001670.019
cell cycle checkpointGO:000007520.019
homeostatic processGO:00425923310.019
positive regulation of apoptotic processGO:00430651540.018
negative regulation of nervous system developmentGO:0051961790.018
calcium ion homeostasisGO:00550741620.018
negative regulation of cell communicationGO:00106481580.018
positive regulation of response to stimulusGO:00485842850.018
cardiac muscle contractionGO:0060048270.018
regulation of nucleotide catabolic processGO:0030811650.018
negative regulation of multicellular organismal processGO:00512412030.018
Human
negative regulation of cellular biosynthetic processGO:00313271610.018
response to vitaminGO:00332731310.018
regulation of protein metabolic processGO:00512462890.018
muscle system processGO:00030121150.018
Human
regulation of neuron deathGO:19012141150.018
nucleoside phosphate metabolic processGO:00067532830.018
regulation of peptide transportGO:0090087870.018
g protein coupled receptor signaling pathwayGO:00071862420.018
positive regulation of neuron differentiationGO:00456661260.018
nucleobase containing compound catabolic processGO:00346551520.018
organic cyclic compound catabolic processGO:19013611750.018
aromatic compound catabolic processGO:00194391680.017
positive regulation of immune system processGO:0002684900.017
neuron projection developmentGO:00311752730.017
organophosphate metabolic processGO:00196373700.017
immune system processGO:00023762040.017
regulation of secretionGO:00510462240.017
cellular cation homeostasisGO:00300031800.017
regulation of cellular amine metabolic processGO:003323880.017
positive regulation of developmental processGO:00510942830.017
Human
macromolecular complex assemblyGO:00650032730.016
Human
cellular response to organic cyclic compoundGO:00714072020.016
negative regulation of gene expressionGO:00106291990.016
neuron projection morphogenesisGO:00488121220.016
positive regulation of programmed cell deathGO:00430681570.016
anatomical structure formation involved in morphogenesisGO:0048646830.016
Human
anterior posterior pattern specificationGO:000995210.016
regulation of system processGO:00440572080.016
Human
positive regulation of cellular amine metabolic processGO:003324030.016
protein complex assemblyGO:00064612630.016
Human
cellular component movementGO:00069282480.016
regulation of cellular protein metabolic processGO:00322682670.015
negative regulation of transportGO:00510511360.015
regulation of catabolic processGO:00098941130.015
cell type specific apoptotic processGO:00972851340.015
positive regulation of cell differentiationGO:00455972170.015
Human
cardiac muscle tissue morphogenesisGO:005500810.015
regulation of phosphorylationGO:00423252480.015
positive regulation of hydrolase activityGO:0051345860.015
muscle contractionGO:0006936880.015
Human
gastrulationGO:000736920.015
regenerationGO:00310991630.015
response to oxidative stressGO:00069791860.015
rhythmic processGO:00485111560.015
regulation of intracellular signal transductionGO:19025312180.015
purine ribonucleotide metabolic processGO:00091502270.015
cellular response to growth factor stimulusGO:00713631620.015
response to insulinGO:00328681330.015
nitrogen compound transportGO:00717052290.015
cellular calcium ion homeostasisGO:00068741600.015
metal ion homeostasisGO:00550651860.015
cellular response to hormone stimulusGO:00328702470.015
cellular metal ion homeostasisGO:00068751720.015
regulation of cellular component movementGO:00512701500.015
cellular response to abiotic stimulusGO:0071214850.015
cardiac chamber developmentGO:000320510.015
mesoderm developmentGO:000749820.015
positive regulation of secretionGO:00510471400.015
ras protein signal transductionGO:0007265290.015
regulation of purine nucleotide metabolic processGO:19005421150.014
heart processGO:0003015570.014
proteolysisGO:00065081750.014
organic substance catabolic processGO:19015753160.014
carbohydrate derivative metabolic processGO:19011353460.014
response to carbohydrateGO:00097431830.014
intracellular transportGO:00469071850.014
single organism catabolic processGO:00447122830.014
positive regulation of catalytic activityGO:00430851840.014
positive regulation of neurogenesisGO:00507691650.014
purine ribonucleoside metabolic processGO:00461281680.014
establishment of protein localizationGO:00451841410.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
response to calcium ionGO:0051592590.014
axis specificationGO:000979840.014
cellular response to lipidGO:00713962010.014
positive regulation of gtpase activityGO:0043547470.014
cell migrationGO:00164771970.014
single organism behaviorGO:00447081300.013
positive regulation of cell projection organizationGO:00313461110.013
cellular response to nitrogen compoundGO:19016992100.013
growthGO:00400071650.013
multi organism reproductive processGO:00447032620.013
wound healingGO:00420601220.013
ribonucleoside metabolic processGO:00091191740.013
positive regulation of ion transportGO:0043270940.013
regulation of protein modification processGO:00313991940.013
nucleoside triphosphate catabolic processGO:00091431230.013
positive regulation of phosphate metabolic processGO:00459372620.013
negative regulation of molecular functionGO:00440921330.013
muscle tissue morphogenesisGO:006041510.013
sequestering of metal ionGO:005123890.013
cardiovascular system developmentGO:00723581340.013
Human
muscle cell differentiationGO:0042692520.013
Human
cytoplasmic transportGO:00164821150.013
muscle organ morphogenesisGO:004864410.013
purine nucleoside triphosphate metabolic processGO:00091441410.012
transmembrane transportGO:00550854120.012
positive regulation of neuron deathGO:1901216430.012
response to estrogenGO:00436272320.012
regulation of membrane potentialGO:00423911100.012
response to glucoseGO:00097491360.012
neuron apoptotic processGO:0051402880.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
developmental growthGO:00485891000.012
response to heatGO:0009408600.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
protein complex biogenesisGO:00702712630.012
Human
response to nutrientGO:00075842480.012
positive regulation of nervous system developmentGO:00519621780.012
protein transportGO:00150311320.012
cell morphogenesis involved in differentiationGO:00009041190.012
response to growth factorGO:00708481890.012
negative regulation of catalytic activityGO:00430861030.012
embryonic pattern specificationGO:000988010.012
response to biotic stimulusGO:00096072260.012
regulation of protein phosphorylationGO:00019321830.012
purine ribonucleoside catabolic processGO:00461301240.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
positive regulation of phosphorus metabolic processGO:00105622620.012
organ morphogenesisGO:0009887750.012
cellular ion homeostasisGO:00068731840.012
cell cell signalingGO:00072673350.012
negative regulation of protein metabolic processGO:00512481140.012
purine nucleotide catabolic processGO:00061951360.012
negative regulation of transcription dna templatedGO:00458921160.012
endocytosisGO:0006897840.012
negative regulation of cell differentiationGO:0045596990.012
purine nucleoside metabolic processGO:00422781690.012
circadian rhythmGO:0007623880.012
regulation of defense responseGO:0031347680.012
response to ionizing radiationGO:0010212590.011
negative regulation of response to stimulusGO:00485851550.011
positive regulation of secretion by cellGO:19035321280.011
regulation of anatomical structure sizeGO:00900661350.011
macromolecule localizationGO:00330362520.011
divalent inorganic cation homeostasisGO:00725071650.011
negative regulation of cell proliferationGO:00082851190.011
sequestering of calcium ionGO:005120880.011
cellular macromolecule localizationGO:00707271220.011
lipid metabolic processGO:00066292830.011
regulation of gtpase activityGO:0043087570.011
regulation of canonical wnt signaling pathwayGO:006082840.011
positive regulation of intracellular signal transductionGO:19025331380.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
salivary gland developmentGO:000743130.011
regulation of hormone levelsGO:00108171870.011
cell cycleGO:00070491010.011
regulation of purine nucleotide catabolic processGO:0033121650.011
positive regulation of cell developmentGO:00107201760.011
purine ribonucleotide catabolic processGO:00091541360.011
divalent inorganic cation transportGO:00725111340.011
response to transition metal nanoparticleGO:19902671220.011
fatty acid metabolic processGO:0006631990.011
cell motilityGO:00488702020.011
bmp signaling pathwayGO:003050940.011
purine containing compound catabolic processGO:00725231380.011
positive regulation of phosphorylationGO:00423271770.011
regulation of immune system processGO:00026821230.011
protein oligomerizationGO:00512591910.011
cellular protein localizationGO:00346131220.010
potassium ion transportGO:0006813970.010
positive regulation of catabolic processGO:0009896780.010
camera type eye developmentGO:0043010480.010
negative regulation of developmental processGO:00510931250.010
dephosphorylationGO:0016311980.010
guanosine containing compound metabolic processGO:1901068740.010
regulation of neuron apoptotic processGO:0043523830.010
gtp metabolic processGO:0046039720.010
response to testosteroneGO:0033574550.010
cytosolic calcium ion homeostasisGO:00514801400.010
insulin like growth factor receptor signaling pathwayGO:004800930.010
nucleoside phosphate catabolic processGO:19012921400.010
negative regulation of neurogenesisGO:0050768780.010
gamete generationGO:00072761240.010
organic anion transportGO:00157111320.010
regulation of kinase activityGO:00435491170.010
glycosyl compound catabolic processGO:19016581260.010
agingGO:00075682410.010
Human
regulation of body fluid levelsGO:0050878900.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
eye morphogenesisGO:004859240.010
negative regulation of phosphorus metabolic processGO:0010563800.010

Srf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029
eye diseaseDOID:561400.020
eye and adnexa diseaseDOID:149200.020
sensory system diseaseDOID:005015500.020
cardiovascular system diseaseDOID:128700.013
myopathyDOID:42300.013
muscular diseaseDOID:008000000.013
heart diseaseDOID:11400.013
cardiomyopathyDOID:005070000.013
muscle tissue diseaseDOID:6600.013
musculoskeletal system diseaseDOID:1700.013
intrinsic cardiomyopathyDOID:006003600.013