Rattus norvegicus

30 known processes

Lox

lysyl oxidase

(Aliases: Rrg1,H-rev142)

Lox biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic skeletal system developmentGO:004870630.537
cellular response to endogenous stimulusGO:00714953770.527
response to woundingGO:00096112540.517
skeletal system morphogenesisGO:0048705120.474
response to transforming growth factor betaGO:0071559460.433
transforming growth factor beta receptor signaling pathwayGO:0007179180.429
formation of primary germ layerGO:000170410.354
tissue developmentGO:00098882520.336
positive regulation of response to stimulusGO:00485842850.307
response to oxygen levelsGO:00704822650.273
response to nutrientGO:00075842480.267
response to growth factorGO:00708481890.253
peptide cross linkingGO:001814910.251
response to nutrient levelsGO:00316673700.244
cellular response to transforming growth factor beta stimulusGO:0071560410.237
regulation of transcription dna templatedGO:00063553740.230
enzyme linked receptor protein signaling pathwayGO:00071671160.227
response to amino acidGO:0043200750.209
response to fibroblast growth factorGO:0071774290.206
odontogenesisGO:0042476320.205
cellular response to lipidGO:00713962010.201
ossificationGO:0001503700.197
positive regulation of developmental processGO:00510942830.192
embryonic cranial skeleton morphogenesisGO:004870120.179
multicellular organism reproductionGO:00325042330.176
programmed cell deathGO:00125013920.175
cell morphogenesisGO:00009021420.175
regulation of programmed cell deathGO:00430673410.171
response to corticosteroidGO:00319602350.170
embryonic skeletal system morphogenesisGO:004870430.169
response to hypoxiaGO:00016662310.165
response to extracellular stimulusGO:00099913800.155
positive regulation of macromolecule biosynthetic processGO:00105572470.155
cellular response to growth factor stimulusGO:00713631620.149
cellular response to oxygen containing compoundGO:19017013860.146
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.143
cell motilityGO:00488702020.142
regulation of rna biosynthetic processGO:20011413810.141
regulation of catalytic activityGO:00507903040.137
response to vitaminGO:00332731310.137
wound healingGO:00420601220.135
defense responseGO:00069521940.134
protein complex subunit organizationGO:00718223020.133
organ morphogenesisGO:0009887750.132
cellular response to platelet derived growth factor stimulusGO:003612070.130
digestive system developmentGO:0055123410.127
regulation of multicellular organismal developmentGO:20000263760.126
regulation of cell proliferationGO:00421273590.123
positive regulation of cell motilityGO:2000147970.118
growthGO:00400071650.117
agingGO:00075682410.117
lipid metabolic processGO:00066292830.116
gastrulationGO:000736920.116
positive regulation of cellular biosynthetic processGO:00313282950.116
response to estradiolGO:00323551640.115
negative regulation of cell deathGO:00605482290.114
eye morphogenesisGO:004859240.114
localization of cellGO:00516742020.110
cellular component movementGO:00069282480.106
positive regulation of cell differentiationGO:00455972170.105
regulation of neurogenesisGO:00507672470.101
positive regulation of stress activated protein kinase signaling cascadeGO:0070304170.099
regulation of nucleic acid templated transcriptionGO:19035063800.099
placenta developmentGO:0001890220.098
regulation of cell developmentGO:00602842630.097
neuron projection developmentGO:00311752730.097
regulation of response to stressGO:00801341260.094
peptidyl lysine hydroxylationGO:001718510.094
intermediate filament bundle assemblyGO:004511010.092
neuron developmentGO:00486662860.091
positive regulation of gene expressionGO:00106282440.089
anatomical structure morphogenesisGO:00096532980.089
reproductive structure developmentGO:00486081280.088
response to monosaccharideGO:00342841590.088
smooth muscle cell migrationGO:0014909360.087
lipid biosynthetic processGO:00086101280.086
neuron differentiationGO:00301823680.086
rna metabolic processGO:00160704060.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.082
digestive tract developmentGO:0048565390.081
peptidyl amino acid modificationGO:00181931260.081
heart morphogenesisGO:000300730.080
cell adhesionGO:00071551100.080
regulation of molecular functionGO:00650093980.080
multi multicellular organism processGO:00447061380.079
cellular response to cytokine stimulusGO:00713451270.079
positive regulation of cell migrationGO:0030335960.078
cellular response to hormone stimulusGO:00328702470.078
negative regulation of cell proliferationGO:00082851190.078
cartilage developmentGO:0051216220.078
cell projection organizationGO:00300303020.076
response to decreased oxygen levelsGO:00362932370.076
regulation of neutrophil apoptotic processGO:003302940.075
response to estrogenGO:00436272320.075
response to external biotic stimulusGO:00432072210.075
Rat
extracellular matrix organizationGO:0030198130.074
skeletal system developmentGO:0001501410.074
response to glucoseGO:00097491360.074
response to biotic stimulusGO:00096072260.074
Rat
carbohydrate derivative metabolic processGO:19011353460.073
response to ketoneGO:19016541820.072
regulation of rna metabolic processGO:00512523910.072
positive regulation of multicellular organismal processGO:00512403870.071
cell migrationGO:00164771970.070
protein complex assemblyGO:00064612630.070
anterior posterior pattern specificationGO:000995210.069
response to purine containing compoundGO:00140741260.068
response to transition metal nanoparticleGO:19902671220.067
vasculature developmentGO:0001944700.066
Rat
cellular response to acid chemicalGO:0071229750.066
astrocyte developmentGO:001400240.066
cellular response to organic cyclic compoundGO:00714072020.065
cellular response to fibroblast growth factor stimulusGO:0044344240.065
macromolecular complex subunit organizationGO:00439333390.064
reproductive processGO:00224143720.064
multicellular organismal reproductive processGO:00486092330.064
positive regulation of stress activated mapk cascadeGO:0032874170.063
response to fatty acidGO:0070542650.063
developmental process involved in reproductionGO:00030061590.063
cellular response to ketoneGO:1901655510.062
cellular response to bmp stimulusGO:007177360.062
positive regulation of cell deathGO:00109421840.061
regulation of cellular component organizationGO:00511283680.061
response to molecule of bacterial originGO:00022371940.061
Rat
response to hexoseGO:00097461440.060
oxoacid metabolic processGO:00434362900.060
cellular response to prostaglandin stimulusGO:007137970.060
apoptotic processGO:00069153810.059
regulation of neuron projection developmentGO:00109751610.058
positive regulation of non canonical wnt signaling pathwayGO:200005210.058
negative regulation of gene expressionGO:00106291990.057
positive regulation of catalytic activityGO:00430851840.057
regulation of apoptotic processGO:00429813350.057
biological adhesionGO:00226101100.057
tissue remodelingGO:0048771400.057
respiratory system developmentGO:0060541450.056
locomotionGO:00400112370.055
response to glucocorticoidGO:00513842230.054
proteolysisGO:00065081750.054
intermediate filament organizationGO:004510910.053
positive regulation of biosynthetic processGO:00098913190.053
multicellular organismal macromolecule metabolic processGO:0044259210.053
single organism biosynthetic processGO:00447113420.051
protein complex biogenesisGO:00702712630.051
nucleic acid templated transcriptionGO:00976593790.051
negative regulation of response to stimulusGO:00485851550.050
response to cytokineGO:00340972150.049
neutrophil apoptotic processGO:000178140.049
reproductionGO:00000032450.049
regulation of cell projection organizationGO:00313441750.049
bone developmentGO:0060348250.048
cellular response to vitamin eGO:007130630.048
decidualizationGO:0046697140.048
positive regulation of transportGO:00510502450.048
renal system developmentGO:0072001670.048
regulation of cell differentiationGO:00455953200.046
protein lipid complex remodelingGO:003436810.045
neuron apoptotic processGO:0051402880.044
connective tissue developmentGO:0061448330.044
growth plate cartilage developmentGO:000341720.044
positive regulation of response to external stimulusGO:0032103510.044
developmental growthGO:00485891000.043
positive regulation of transcription dna templatedGO:00458931970.043
embryonic pattern specificationGO:000988010.042
reproductive system developmentGO:00614581280.042
negative regulation of macromolecule metabolic processGO:00106052600.042
cellular response to tumor necrosis factorGO:0071356460.042
cellular component morphogenesisGO:00329891550.042
negative regulation of cell differentiationGO:0045596990.041
regulation of nervous system developmentGO:00519602640.041
negative regulation of metabolic processGO:00098923310.041
cellular response to external stimulusGO:00714961180.040
response to lipopolysaccharideGO:00324961910.040
Rat
cartilage development involved in endochondral bone morphogenesisGO:006035130.040
regulation of cellular response to stressGO:0080135490.040
schwann cell migrationGO:003613520.040
ion transmembrane transportGO:00342203650.040
response to mechanical stimulusGO:00096121340.040
positive regulation of cellular component organizationGO:00511302000.040
transcription dna templatedGO:00063513770.040
regulation of neuron apoptotic processGO:0043523830.039
lens development in camera type eyeGO:0002088130.039
regulation of epithelial to mesenchymal transitionGO:001071720.039
response to reactive oxygen speciesGO:00003021200.039
chemotaxisGO:0006935660.039
central nervous system developmentGO:00074173110.039
response to toxic substanceGO:00096361330.039
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.039
regulation of response to woundingGO:1903034690.039
regulation of schwann cell migrationGO:190014720.039
circulatory system developmentGO:00723591340.038
Rat
cellular response to lipopolysaccharideGO:0071222550.038
cell part morphogenesisGO:00329901230.038
response to tumor necrosis factorGO:0034612560.038
response to carbohydrateGO:00097431830.038
cellular response to stressGO:00335542690.038
sulfur compound metabolic processGO:0006790700.038
vesicle mediated transportGO:00161921810.038
regenerationGO:00310991630.037
gamete generationGO:00072761240.037
camera type eye morphogenesisGO:004859320.037
positive regulation of jnk cascadeGO:0046330130.037
positive regulation of stem cell differentiationGO:200073820.036
positive regulation of signal transductionGO:00099671750.036
chylomicron remodelingGO:003437110.036
positive regulation of apoptotic processGO:00430651540.036
cardiac muscle contractionGO:0060048270.035
cellular response to interleukin 1GO:0071347370.035
intracellular signal transductionGO:00355563140.035
response to increased oxygen levelsGO:0036296450.034
positive regulation of neuron differentiationGO:00456661260.034
chondrocyte differentiationGO:0002062100.034
regulation of phosphorylationGO:00423252480.034
response to campGO:0051591910.034
rna biosynthetic processGO:00327743800.034
sex differentiationGO:00075481130.033
regulation of signal transductionGO:00099663180.033
negative regulation of transcription dna templatedGO:00458921160.033
positive regulation of cell communicationGO:00106472710.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
cardiovascular system developmentGO:00723581340.032
Rat
response to metal ionGO:00100382530.032
positive regulation of cell developmentGO:00107201760.032
organic acid metabolic processGO:00060822920.032
anatomical structure formation involved in morphogenesisGO:0048646830.032
female pregnancyGO:00075651220.032
positive regulation of nervous system developmentGO:00519621780.032
positive regulation of neuron projection developmentGO:0010976990.032
regulation of response to external stimulusGO:00321011060.031
positive regulation of programmed cell deathGO:00430681570.031
inflammatory responseGO:00069541500.031
epithelium developmentGO:0060429960.030
cellular response to nicotineGO:007131670.030
positive regulation of locomotionGO:00400171020.030
lung developmentGO:0030324430.030
response to peptide hormoneGO:00434342780.030
eye developmentGO:0001654500.030
response to other organismGO:00517072200.030
Rat
catabolic processGO:00090563510.029
response to oxidative stressGO:00069791860.029
regulation of anatomical structure morphogenesisGO:00226031410.029
inflammatory cell apoptotic processGO:000692550.029
protein localizationGO:00081041910.028
regulation of mapk cascadeGO:00434081160.028
morphogenesis of an epitheliumGO:0002009200.028
homeostatic processGO:00425923310.028
neuron projection morphogenesisGO:00488121220.028
morphogenesis of a polarized epitheliumGO:000173810.028
urogenital system developmentGO:0001655780.028
endochondral bone growthGO:000341630.027
purine containing compound metabolic processGO:00725212530.027
positive regulation of neurogenesisGO:00507691650.026
regulation of cell morphogenesis involved in differentiationGO:0010769720.026
regulation of aldosterone biosynthetic processGO:003234720.026
brain developmentGO:00074202470.026
response to peptideGO:19016522920.026
positive regulation of rna biosynthetic processGO:19026801970.026
cellular response to vitaminGO:0071295210.026
regulation of cell morphogenesisGO:0022604770.026
cellular ketone metabolic processGO:0042180510.026
positive regulation of molecular functionGO:00440932300.026
kidney developmentGO:0001822670.026
ribose phosphate metabolic processGO:00196932350.025
organic substance catabolic processGO:19015753160.025
digestive tract morphogenesisGO:004854680.025
macromolecular complex assemblyGO:00650032730.025
regulation of cellular response to growth factor stimulusGO:0090287150.025
single organism reproductive processGO:00447022970.025
positive regulation of phosphorus metabolic processGO:00105622620.025
response to zinc ionGO:0010043390.025
endocrine hormone secretionGO:0060986210.025
astrocyte differentiationGO:0048708190.024
cell matrix adhesionGO:0007160190.024
ras protein signal transductionGO:0007265290.024
cellular component biogenesisGO:00440853680.024
regulation of cell migrationGO:00303341280.024
head developmentGO:00603222470.024
positive regulation of hydrolase activityGO:0051345860.024
transcription from rna polymerase ii promoterGO:00063662520.024
regulation of reactive oxygen species metabolic processGO:2000377260.024
regulation of proteolysisGO:0030162660.023
negative regulation of cell communicationGO:00106481580.023
collagen metabolic processGO:0032963210.023
regulation of cell motilityGO:20001451310.023
response to dexamethasoneGO:0071548490.023
carbohydrate derivative biosynthetic processGO:19011371240.023
embryo developmentGO:0009790490.023
lipid localizationGO:0010876620.023
organophosphate metabolic processGO:00196373700.023
muscle cell migrationGO:0014812360.023
response to calcium ionGO:0051592590.023
regulation of cellular component movementGO:00512701500.023
integrin mediated signaling pathwayGO:000722970.023
regulation of cellular protein metabolic processGO:00322682670.022
positive regulation of inflammatory responseGO:0050729240.022
regulation of metalloenzyme activityGO:004855210.022
regulation of cellular ketone metabolic processGO:0010565270.022
negative regulation of signalingGO:00230571570.022
gonad developmentGO:00084061040.022
regulation of blood pressureGO:0008217830.022
regulation of plasma lipoprotein particle levelsGO:009700630.022
respiratory tube developmentGO:0030323430.022
response to foodGO:0032094270.022
cellular response to nutrient levelsGO:0031669600.022
positive regulation of signalingGO:00230562700.021
negative regulation of multicellular organismal processGO:00512412030.021
cellular response to mechanical stimulusGO:0071260480.021
protein catabolic processGO:0030163300.021
regulation of anatomical structure sizeGO:00900661350.021
secretion by cellGO:00329402480.021
carboxylic acid metabolic processGO:00197522890.021
response to bacteriumGO:00096172000.021
Rat
cytosolic calcium ion homeostasisGO:00514801400.021
macromolecule catabolic processGO:0009057580.021
cell morphogenesis involved in neuron differentiationGO:00486671060.021
negative regulation of programmed cell deathGO:00430691830.021
blood circulationGO:00080151830.021
cell morphogenesis involved in differentiationGO:00009041190.021
response to inorganic substanceGO:00100353770.021
negative regulation of cellular component organizationGO:0051129830.020
positive regulation of intracellular protein transportGO:0090316200.020
regulation of peptidase activityGO:0052547550.020
development of primary sexual characteristicsGO:00451371070.020
rhythmic processGO:00485111560.020
hormone secretionGO:00468791150.020
chordate embryonic developmentGO:0043009180.020
maternal process involved in female pregnancyGO:0060135380.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
developmental growth involved in morphogenesisGO:0060560330.020
regulation of phosphorus metabolic processGO:00511743490.020
male gonad developmentGO:0008584590.019
regulation of neuron differentiationGO:00456642080.019
negative regulation of protein metabolic processGO:00512481140.019
regulation of phosphate metabolic processGO:00192203490.019
positive regulation of cellular protein metabolic processGO:00322701670.019
regulation of smooth muscle cell migrationGO:0014910360.019
protein phosphorylationGO:00064683450.019
positive regulation of biomineral tissue developmentGO:007016940.019
regulation of nucleotide metabolic processGO:00061401170.019
adrenal gland developmentGO:0030325110.019
signal transduction by phosphorylationGO:00230141440.019
female gonad developmentGO:0008585530.019
cellular response to fluorideGO:190261810.019
response to organophosphorusGO:00466831020.018
steroid metabolic processGO:0008202730.018
cellular response to glucocorticoid stimulusGO:0071385680.018
negative regulation of apoptotic processGO:00430661810.018
cell type specific apoptotic processGO:00972851340.018
response to vitamin dGO:0033280340.018
neuron deathGO:00709971270.018
regulation of bmp signaling pathwayGO:003051020.018
tissue morphogenesisGO:0048729220.018
response to indole 3 methanolGO:007168020.018
cellular response to organonitrogen compoundGO:00714171970.018
regulation of proteasomal protein catabolic processGO:006113640.018
regulation of jnk cascadeGO:0046328190.018
cellular response to metal ionGO:0071248550.018
response to hyperoxiaGO:0055093450.018
positive regulation of cell projection organizationGO:00313461110.017
glial cell migrationGO:0008347110.017
cellular chemical homeostasisGO:00550822470.017
intramembranous ossificationGO:000195710.017
cellular response to biotic stimulusGO:0071216590.017
response to axon injuryGO:0048678590.017
intracellular protein transportGO:0006886790.017
negative regulation of rna biosynthetic processGO:19026791180.017
epithelial cell differentiationGO:0030855710.017
stem cell differentiationGO:0048863160.017
cellular response to alkaloidGO:0071312250.017
positive regulation of cellular component movementGO:00512721020.017
purine ribonucleotide catabolic processGO:00091541360.017
regulation of inflammatory responseGO:0050727480.017
cellular response to alcoholGO:0097306870.017
skin morphogenesisGO:004358920.016
regulation of cytokine productionGO:0001817560.016
tissue regenerationGO:0042246360.016
cation transmembrane transportGO:00986552630.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.016
proteoglycan metabolic processGO:000602930.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
intermediate filament based processGO:004510330.016
response to temperature stimulusGO:0009266940.016
cellular homeostasisGO:00197252520.016
positive regulation of lipid biosynthetic processGO:0046889250.016
regulation of cellular amino acid metabolic processGO:000652120.016
metal ion transportGO:00300012890.016
cellular response to peptideGO:19016531330.016
negative regulation of biosynthetic processGO:00098901680.016
regulation of extent of cell growthGO:0061387250.016
positive regulation of smooth muscle cell migrationGO:0014911270.016
regulation of transforming growth factor beta receptor signaling pathwayGO:001701550.016
cellular response to extracellular stimulusGO:0031668730.016
tube developmentGO:0035295890.015
positive regulation of secretionGO:00510471400.015
regulation of chemotaxisGO:0050920290.015
positive regulation of rna metabolic processGO:00512542030.015
stress activated mapk cascadeGO:0051403350.015
cellular catabolic processGO:00442482950.015
positive regulation of muscle contractionGO:0045933220.015
positive regulation of protein transportGO:0051222410.015
response to folic acidGO:0051593140.015
neuron projection regenerationGO:0031102350.015
synaptic transmissionGO:00072682350.015
cell substrate adhesionGO:0031589290.015
organonitrogen compound catabolic processGO:19015651790.015
secretionGO:00469033070.015
negative regulation of neuron differentiationGO:0045665620.015
tube morphogenesisGO:0035239230.015
positive regulation of protein metabolic processGO:00512471780.015
negative regulation of developmental processGO:00510931250.015
neurological system processGO:00508772190.014
cellular component assemblyGO:00226073600.014
regulation of transmembrane transportGO:00347621220.014
camera type eye developmentGO:0043010480.014
heart developmentGO:0007507720.014
multi organism reproductive processGO:00447032620.014
axon developmentGO:0061564960.014
protein processingGO:0016485680.014
biomineral tissue developmentGO:0031214120.014
muscle contractionGO:0006936880.014
blood vessel developmentGO:0001568690.014
Rat
chemical homeostasisGO:00488782920.014
galactolipid catabolic processGO:001937610.014
small gtpase mediated signal transductionGO:0007264360.014
collagen fibril organizationGO:003019910.014
regulation of neuron deathGO:19012141150.014
cerebral cortex cell migrationGO:002179540.014
regulation of hydrolase activityGO:00513361430.014
hormone transportGO:00099141210.014
response to vitamin eGO:0033197240.014
dna metabolic processGO:0006259960.014
regulation of stem cell differentiationGO:200073620.014
response to epidermal growth factorGO:0070849180.014
negative regulation of signal transductionGO:0009968830.014
response to hydrogen peroxideGO:0042542890.014
macromolecule localizationGO:00330362520.014
regulation of intracellular transportGO:0032386650.014
nucleoside phosphate metabolic processGO:00067532830.014
regulation of muscle system processGO:0090257790.014
cellular response to nutrientGO:0031670300.013
multicellular organismal homeostasisGO:0048871490.013
cellular macromolecule localizationGO:00707271220.013
cellular response to retinoic acidGO:0071300270.013
protein transportGO:00150311320.013
regulation of hormone levelsGO:00108171870.013
negative regulation of nervous system developmentGO:0051961790.013
purine ribonucleotide metabolic processGO:00091502270.013
development of primary male sexual characteristicsGO:0046546590.013
cellular response to peptide hormone stimulusGO:00713751200.013
female sex differentiationGO:0046660590.013
axon regenerationGO:0031103280.013
positive regulation of phosphate metabolic processGO:00459372620.013
sexual reproductionGO:00199531480.013
single organism intracellular transportGO:19025821660.013
extracellular structure organizationGO:0043062130.013
response to mineralocorticoidGO:0051385490.013
regulation of embryonic developmentGO:004599520.013
cellular amino acid metabolic processGO:00065201070.013
stress activated protein kinase signaling cascadeGO:0031098370.013
cellular response to epidermal growth factor stimulusGO:0071364120.012
male gamete generationGO:0048232990.012
circulatory system processGO:00030131830.012
negative regulation of canonical wnt signaling pathwayGO:009009040.012
c21 steroid hormone metabolic processGO:0008207140.012
mapk cascadeGO:00001651400.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.012
reactive oxygen species metabolic processGO:0072593370.012
action potentialGO:0001508540.012
regulation of homeostatic processGO:00328441010.012
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051220.012
cellular response to inorganic substanceGO:0071241650.012
regulation of defense responseGO:0031347680.012
wnt signaling pathway planar cell polarity pathwayGO:006007120.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
positive regulation of corticosteroid hormone secretionGO:200084840.012
male sex differentiationGO:0046661640.012
transmembrane transportGO:00550854120.012
single organism catabolic processGO:00447122830.012
protein maturationGO:0051604680.012

Lox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.242
musculoskeletal system diseaseDOID:1700.242
connective tissue diseaseDOID:6500.237
bone diseaseDOID:008000100.237
bone development diseaseDOID:008000600.237
hypertensionDOID:1076300.065
vascular diseaseDOID:17800.065
essential hypertensionDOID:1082500.065
cardiovascular system diseaseDOID:128700.065
artery diseaseDOID:005082800.065
nervous system diseaseDOID:86300.030
eye and adnexa diseaseDOID:149200.030
sensory system diseaseDOID:005015500.030
eye diseaseDOID:561400.030
osteochondrodysplasiaDOID:225600.024
retinal degenerationDOID:846600.017
retinal diseaseDOID:567900.017