Rattus norvegicus

11 known processes

P4hb

prolyl 4-hydroxylase, beta polypeptide

(Aliases: PDIR,PDI)

P4hb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of behaviorGO:0050795610.388
regulation of translationGO:0006417270.287
startle responseGO:000196420.230
multicellular organism reproductionGO:00325042330.229
neuromuscular processGO:005090520.229
organelle organizationGO:00069962660.221
antigen processing and presentation of peptide antigen via mhc class iGO:000247410.194
regulation of cellular protein metabolic processGO:00322682670.181
vesicle mediated transportGO:00161921810.168
tissue developmentGO:00098882520.153
macromolecular complex assemblyGO:00650032730.148
negative regulation of cell deathGO:00605482290.144
positive regulation of cellular component organizationGO:00511302000.140
behaviorGO:00076102050.136
regulation of apoptotic processGO:00429813350.122
Human
multicellular organismal reproductive processGO:00486092330.116
cellular component assemblyGO:00226073600.105
regulation of protein metabolic processGO:00512462890.104
agingGO:00075682410.102
positive regulation of developmental processGO:00510942830.100
negative regulation of cell communicationGO:00106481580.091
central nervous system developmentGO:00074173110.091
proteolysis involved in cellular protein catabolic processGO:0051603190.090
establishment of protein localizationGO:00451841410.088
carbohydrate metabolic processGO:00059751300.086
secretionGO:00469033070.085
cellular component biogenesisGO:00440853680.084
posttranscriptional regulation of gene expressionGO:0010608370.083
positive regulation of endocytosisGO:0045807280.082
cellular catabolic processGO:00442482950.079
positive regulation of biosynthetic processGO:00098913190.077
protein complex assemblyGO:00064612630.076
cardiocyte differentiationGO:0035051220.076
regulation of neurogenesisGO:00507672470.076
reproductive processGO:00224143720.074
positive regulation of protein metabolic processGO:00512471780.073
regulation of cell developmentGO:00602842630.070
regulation of cell migrationGO:00303341280.070
positive regulation of cell proliferationGO:00082842490.068
positive regulation of cell differentiationGO:00455972170.068
positive regulation of cellular biosynthetic processGO:00313282950.067
circulatory system developmentGO:00723591340.065
neuron differentiationGO:00301823680.063
positive regulation of neuron projection developmentGO:0010976990.062
regulation of endocytosisGO:0030100420.061
positive regulation of cell motilityGO:2000147970.061
secretion by cellGO:00329402480.061
positive regulation of gene expressionGO:00106282440.060
protein complex subunit organizationGO:00718223020.060
cardiovascular system developmentGO:00723581340.059
regulation of cellular localizationGO:00603412630.059
response to metal ionGO:00100382530.059
embryonic cranial skeleton morphogenesisGO:004870120.058
skeletal system developmentGO:0001501410.058
cytoskeleton organizationGO:00070101110.057
regulation of neuron differentiationGO:00456642080.057
regulation of programmed cell deathGO:00430673410.056
Human
sexual reproductionGO:00199531480.055
tube developmentGO:0035295890.055
neuron projection morphogenesisGO:00488121220.054
regulation of nervous system developmentGO:00519602640.052
catabolic processGO:00090563510.052
reproductive structure developmentGO:00486081280.051
regulation of anatomical structure sizeGO:00900661350.051
muscle tissue developmentGO:0060537580.050
reproductionGO:00000032450.050
response to ketoneGO:19016541820.048
response to cytokineGO:00340972150.047
cell motilityGO:00488702020.047
taxisGO:0042330670.047
gamete generationGO:00072761240.046
response to other organismGO:00517072200.045
hepatocyte proliferationGO:007257430.045
positive regulation of signal transductionGO:00099671750.044
regulation of transcription dna templatedGO:00063553740.044
negative regulation of signalingGO:00230571570.044
cellular response to endogenous stimulusGO:00714953770.043
response to woundingGO:00096112540.043
regulation of phagocytosisGO:0050764130.043
organ morphogenesisGO:0009887750.043
macromolecular complex subunit organizationGO:00439333390.043
brain developmentGO:00074202470.042
dna metabolic processGO:0006259960.042
wound healingGO:00420601220.042
motor neuron axon guidanceGO:000804510.042
macromolecule glycosylationGO:0043413140.041
establishment of vesicle localizationGO:0051650310.041
cell projection organizationGO:00300303020.040
endocytosisGO:0006897840.040
regulation of cell differentiationGO:00455953200.039
antigen processing and presentationGO:001988220.039
cell migrationGO:00164771970.038
positive regulation of cellular protein metabolic processGO:00322701670.038
regulation of signal transductionGO:00099663180.038
Human
regulation of molecular functionGO:00650093980.038
response to estradiolGO:00323551640.037
vesicle localizationGO:0051648330.036
positive regulation of response to stimulusGO:00485842850.036
positive regulation of dna metabolic processGO:0051054390.036
regulation of chemotaxisGO:0050920290.036
chemosensory behaviorGO:000763520.035
cell adhesionGO:00071551100.035
cellular homeostasisGO:00197252520.035
positive regulation of nitrogen compound metabolic processGO:00511733340.035
regulation of cellular component movementGO:00512701500.034
positive regulation of cell developmentGO:00107201760.034
neuron projection developmentGO:00311752730.034
purine ribonucleoside catabolic processGO:00461301240.033
reproductive system developmentGO:00614581280.033
positive regulation of neurogenesisGO:00507691650.033
cellular response to oxygen containing compoundGO:19017013860.033
head developmentGO:00603222470.033
urogenital system developmentGO:0001655780.032
regulation of organelle organizationGO:0033043800.032
homeostatic processGO:00425923310.031
defense responseGO:00069521940.030
transcription dna templatedGO:00063513770.030
response to inorganic substanceGO:00100353770.030
antigen processing and presentation of peptide antigenGO:004800220.030
peptidyl lysine hydroxylationGO:001718510.030
multi organism reproductive processGO:00447032620.029
single organism catabolic processGO:00447122830.029
camera type eye developmentGO:0043010480.029
regulation of nucleic acid templated transcriptionGO:19035063800.029
chemical homeostasisGO:00488782920.029
cellular response to vascular endothelial growth factor stimulusGO:003592460.029
regulation of cell motilityGO:20001451310.028
nucleic acid templated transcriptionGO:00976593790.028
response to growth factorGO:00708481890.027
exocytosisGO:0006887600.027
regulation of anatomical structure morphogenesisGO:00226031410.027
regulation of coagulationGO:0050818110.027
negative regulation of multicellular organismal processGO:00512412030.027
heart developmentGO:0007507720.027
embryonic skeletal system morphogenesisGO:004870430.027
cellular chemical homeostasisGO:00550822470.026
response to nutrient levelsGO:00316673700.026
positive regulation of apoptotic processGO:00430651540.026
positive regulation of cell communicationGO:00106472710.026
translationGO:0006412350.026
regulation of protein localizationGO:0032880810.026
epithelium developmentGO:0060429960.026
protein complex biogenesisGO:00702712630.026
cellular response to external stimulusGO:00714961180.026
developmental process involved in reproductionGO:00030061590.025
positive regulation of cell projection organizationGO:00313461110.025
response to hexoseGO:00097461440.025
programmed cell deathGO:00125013920.025
Human
cellular response to stressGO:00335542690.025
Human
regulation of secretionGO:00510462240.025
biological adhesionGO:00226101100.025
negative regulation of metabolic processGO:00098923310.024
cellular response to growth factor stimulusGO:00713631620.024
blood circulationGO:00080151830.024
negative regulation of cellular amide metabolic processGO:003424910.024
regulation of locomotionGO:00400121480.024
cellular response to unfolded proteinGO:003462020.023
epithelial cell proliferationGO:0050673540.022
regulation of cell adhesionGO:0030155520.022
positive regulation of phagocytosisGO:005076690.022
cellular protein complex assemblyGO:0043623440.022
negative regulation of catalytic activityGO:00430861030.022
regulation of cell substrate adhesionGO:0010810180.022
axon extensionGO:0048675260.021
regulation of multicellular organismal developmentGO:20000263760.021
protein oligomerizationGO:00512591910.021
proteolysisGO:00065081750.021
cellular response to metal ionGO:0071248550.021
anatomical structure morphogenesisGO:00096532980.021
regulation of tube sizeGO:0035150890.021
rna biosynthetic processGO:00327743800.021
regulation of rna metabolic processGO:00512523910.021
formation of primary germ layerGO:000170410.020
regulation of cellular component biogenesisGO:0044087860.020
eye developmentGO:0001654500.020
glucose homeostasisGO:0042593750.020
regulation of hydrolase activityGO:00513361430.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
spermatogenesisGO:0007283990.020
positive regulation of signalingGO:00230562700.019
regulation of cell proliferationGO:00421273590.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
male gamete generationGO:0048232990.019
olfactory behaviorGO:004204820.019
regulation of actin nucleationGO:005112520.019
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.019
carbohydrate derivative metabolic processGO:19011353460.019
organic cyclic compound catabolic processGO:19013611750.019
cell substrate adhesionGO:0031589290.019
regulation of protein transportGO:0051223680.018
cellular response to cytokine stimulusGO:00713451270.018
localization of cellGO:00516742020.018
organic substance catabolic processGO:19015753160.018
single organism organelle organizationGO:19025891800.018
positive regulation of phosphate metabolic processGO:00459372620.018
multicellular organism growthGO:003526410.018
establishment of organelle localizationGO:0051656370.018
positive regulation of phosphorus metabolic processGO:00105622620.018
cellular ketone metabolic processGO:0042180510.017
regulation of catalytic activityGO:00507903040.017
purine ribonucleoside metabolic processGO:00461281680.017
lipid storageGO:001991510.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
response to glucoseGO:00097491360.017
epithelial cell differentiationGO:0030855710.017
growthGO:00400071650.016
single organism carbohydrate metabolic processGO:00447231180.016
single organism intracellular transportGO:19025821660.016
negative regulation of cellular protein metabolic processGO:00322691060.016
positive regulation of molecular functionGO:00440932300.016
cellular component morphogenesisGO:00329891550.016
response to reactive oxygen speciesGO:00003021200.016
multicellular organismal catabolic processGO:004424320.016
eye morphogenesisGO:004859240.016
positive regulation of nervous system developmentGO:00519621780.016
locomotionGO:00400112370.016
circulatory system processGO:00030131830.016
axon developmentGO:0061564960.016
cellular amine metabolic processGO:0044106380.016
regulation of proteolysisGO:0030162660.016
response to peptideGO:19016522920.015
cellular response to hormone stimulusGO:00328702470.015
cell part morphogenesisGO:00329901230.015
regenerationGO:00310991630.015
reactive nitrogen species metabolic processGO:200105710.015
positive regulation of chemotaxisGO:0050921230.015
neuron developmentGO:00486662860.015
triglyceride homeostasisGO:007032820.015
multicellular organismal macromolecule metabolic processGO:0044259210.015
carbohydrate derivative biosynthetic processGO:19011371240.015
regulation of phosphorylationGO:00423252480.015
response to acid chemicalGO:00011012220.014
cellular calcium ion homeostasisGO:00068741600.014
macromolecule localizationGO:00330362520.014
protein localizationGO:00081041910.014
regulation of cell sizeGO:0008361370.014
negative regulation of gene expressionGO:00106291990.014
regulation of cellular component organizationGO:00511283680.014
carbohydrate homeostasisGO:0033500750.014
cellular response to topologically incorrect proteinGO:003596730.014
regulation of rna biosynthetic processGO:20011413810.014
cellular response to organonitrogen compoundGO:00714171970.014
ribose phosphate metabolic processGO:00196932350.014
negative regulation of macromolecule metabolic processGO:00106052600.014
positive regulation of catalytic activityGO:00430851840.014
gastrulationGO:000736920.014
acylglycerol homeostasisGO:005509020.014
cellular response to inorganic substanceGO:0071241650.014
neurological system processGO:00508772190.014
intracellular transportGO:00469071850.014
cytoplasmic transportGO:00164821150.014
negative regulation of response to stimulusGO:00485851550.013
apoptotic processGO:00069153810.013
Human
regulation of cell projection organizationGO:00313441750.013
positive regulation of multicellular organismal processGO:00512403870.013
amine metabolic processGO:0009308380.013
actin cytoskeleton organizationGO:0030036730.013
cellular component movementGO:00069282480.013
autophagyGO:0006914190.013
ion homeostasisGO:00508012120.013
regulation of secretion by cellGO:19035302080.013
salivary gland developmentGO:000743130.013
positive regulation of transportGO:00510502450.013
cellular response to nitrogen compoundGO:19016992100.013
camera type eye morphogenesisGO:004859320.013
regulation of establishment of protein localizationGO:0070201690.012
chromosome segregationGO:000705920.012
negative regulation of protein modification by small protein conjugation or removalGO:190332140.012
regulation of hormone levelsGO:00108171870.012
collagen catabolic processGO:003057420.012
collagen metabolic processGO:0032963210.012
liver morphogenesisGO:007257630.012
negative regulation of synaptic transmissionGO:0050805290.012
single organism behaviorGO:00447081300.012
neural crest cell differentiationGO:001403320.012
protein secretionGO:0009306340.012
dendrite developmentGO:0016358720.012
carbohydrate derivative catabolic processGO:19011361470.012
regulation of kinase activityGO:00435491170.012
synaptic vesicle endocytosisGO:004848840.012
regulation of angiotensin levels in bloodGO:000200220.012
ribonucleotide metabolic processGO:00092592310.012
mapk cascadeGO:00001651400.012
glycoprotein biosynthetic processGO:0009101190.012
regulation of immune system processGO:00026821230.012
response to lead ionGO:0010288330.011
protein transportGO:00150311320.011
response to nutrientGO:00075842480.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
defense response to gram negative bacteriumGO:005082930.011
cell morphogenesisGO:00009021420.011
nucleobase containing small molecule metabolic processGO:00550863160.011
regulation of proteasomal protein catabolic processGO:006113640.011
regulation of cellular amine metabolic processGO:003323880.011
intracellular signal transductionGO:00355563140.011
Human
macromolecule catabolic processGO:0009057580.011
oxidation reduction processGO:00551143040.011
Human Yeast
reactive oxygen species biosynthetic processGO:190340980.011
regulation of neuron projection developmentGO:00109751610.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
macroautophagyGO:001623640.011
cell cell signalingGO:00072673350.011
regulation of cellular component sizeGO:0032535510.011
purine nucleotide metabolic processGO:00061632290.011
positive regulation of cell deathGO:00109421840.011
regulation of cellular amino acid metabolic processGO:000652120.011
positive regulation of cell growthGO:0030307440.011
developmental growthGO:00485891000.011
liver developmentGO:0001889900.011
regulation of developmental growthGO:0048638450.011
protein phosphorylationGO:00064683450.010
regulation of transferase activityGO:00513381230.010
negative regulation of developmental processGO:00510931250.010
cellular metal ion homeostasisGO:00068751720.010
positive regulation of neuron differentiationGO:00456661260.010
respiratory system developmentGO:0060541450.010
positive regulation of cellular component biogenesisGO:0044089550.010
response to monosaccharideGO:00342841590.010
positive regulation of kinase activityGO:0033674770.010
negative regulation of cell developmentGO:0010721820.010
positive regulation of transcription dna templatedGO:00458931970.010
cell matrix adhesionGO:0007160190.010

P4hb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.291
musculoskeletal system diseaseDOID:1700.291
disease of anatomical entityDOID:700.291
bone diseaseDOID:008000100.058
bone development diseaseDOID:008000600.058
osteochondrodysplasiaDOID:225600.048
osteogenesis imperfectaDOID:1234700.048
nervous system diseaseDOID:86300.029
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
organ system cancerDOID:005068600.014