Rattus norvegicus

4 known processes

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

(Aliases: Shp-1,MGC124580,Ptph6)

Ptpn6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327743800.399
Fly
regulation of nucleic acid templated transcriptionGO:19035063800.368
Fly
response to molecule of fungal originGO:000223830.336
cellular response to insulin stimulusGO:0032869810.330
positive regulation of phosphate metabolic processGO:00459372620.303
intracellular signal transductionGO:00355563140.300
Human Mouse
cation transportGO:00068123820.292
Mouse
regulation of phosphate metabolic processGO:00192203490.260
Human Mouse
regulation of cellular protein metabolic processGO:00322682670.245
Human Mouse
anatomical structure morphogenesisGO:00096532980.245
Mouse Fly
neurotrophin trk receptor signaling pathwayGO:0048011100.244
transcription dna templatedGO:00063513770.239
Fly
cellular component movementGO:00069282480.239
Fly
insulin receptor signaling pathwayGO:0008286240.225
rna metabolic processGO:00160704060.223
Fly
organic acid metabolic processGO:00060822920.219
immune responseGO:00069551040.216
Mouse
carboxylic acid metabolic processGO:00197522890.213
regulation of transcription dna templatedGO:00063553740.212
Fly
regulation of phosphorus metabolic processGO:00511743490.207
Human Mouse
protein complex assemblyGO:00064612630.206
vesicle mediated transportGO:00161921810.204
Fly
nucleic acid templated transcriptionGO:00976593790.204
Fly
regulation of protein metabolic processGO:00512462890.195
Human Mouse
positive regulation of nitrogen compound metabolic processGO:00511733340.190
positive regulation of fc receptor mediated stimulatory signaling pathwayGO:006036910.187
cytoskeleton organizationGO:00070101110.183
positive regulation of cellular component organizationGO:00511302000.179
cellular component biogenesisGO:00440853680.176
protein autophosphorylationGO:0046777660.169
regulation of protein modification processGO:00313991940.162
Human Mouse
regulation of rna metabolic processGO:00512523910.158
Fly
purine ribonucleoside metabolic processGO:00461281680.155
nucleobase containing small molecule metabolic processGO:00550863160.154
positive regulation of immunoglobulin productionGO:000263940.144
sequestering of calcium ionGO:005120880.143
cell activationGO:0001775970.143
Mouse
extrinsic apoptotic signaling pathway in absence of ligandGO:009719250.139
regulation of cell proliferationGO:00421273590.138
Human Mouse
neuron apoptotic processGO:0051402880.137
negative regulation of signal transductionGO:0009968830.134
Mouse
cell morphogenesis involved in differentiationGO:00009041190.132
Mouse
aromatic compound catabolic processGO:00194391680.131
apoptotic processGO:00069153810.130
Fly
single organism organelle organizationGO:19025891800.129
immune response regulating signaling pathwayGO:0002764190.128
Mouse
erbb signaling pathwayGO:0038127230.125
Fly
organelle organizationGO:00069962660.125
regulation of protein phosphorylationGO:00019321830.125
Human Mouse
regulation of cellular component organizationGO:00511283680.124
macromolecular complex assemblyGO:00650032730.123
negative regulation of nitrogen compound metabolic processGO:00511721610.122
negative regulation of cell communicationGO:00106481580.122
Mouse
regulation of fc receptor mediated stimulatory signaling pathwayGO:006036830.121
synaptic growth at neuromuscular junctionGO:005112410.119
negative regulation of cellular metabolic processGO:00313242810.118
Human Mouse
immune system processGO:00023762040.116
Mouse
response to other organismGO:00517072200.116
cellular response to peptideGO:19016531330.115
cellular response to endogenous stimulusGO:00714953770.113
Fly
response to peptide hormoneGO:00434342780.113
positive regulation of phosphorus metabolic processGO:00105622620.113
positive regulation of cell deathGO:00109421840.111
regulation of protein kinase activityGO:00458591050.110
Mouse
protein phosphorylationGO:00064683450.108
Human Mouse
cellular response to peptide hormone stimulusGO:00713751200.107
regulation of cytoskeleton organizationGO:0051493490.106
regulation of neuron apoptotic processGO:0043523830.106
enzyme linked receptor protein signaling pathwayGO:00071671160.106
Fly
regulation of phosphorylationGO:00423252480.105
Human Mouse
regulation of programmed cell deathGO:00430673410.104
Fly
negative regulation of phosphorus metabolic processGO:0010563800.103
Human Mouse
macromolecular complex subunit organizationGO:00439333390.103
mononuclear cell proliferationGO:0032943290.102
Mouse
positive regulation of lipid kinase activityGO:009021820.102
protein complex subunit organizationGO:00718223020.101
leukocyte activationGO:0045321760.100
Mouse
negative regulation of response to stimulusGO:00485851550.098
Mouse
purine nucleotide metabolic processGO:00061632290.097
purine ribonucleotide metabolic processGO:00091502270.097
actin filament bundle organizationGO:0061572190.096
regulation of catalytic activityGO:00507903040.096
Mouse
regulation of cell motilityGO:20001451310.094
regulation of apoptotic processGO:00429813350.094
Fly
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.094
mapk cascadeGO:00001651400.092
Human Mouse
protein complex biogenesisGO:00702712630.091
cell cycleGO:00070491010.091
Human Mouse Fly
oxoacid metabolic processGO:00434362900.090
purine containing compound metabolic processGO:00725212530.090
regulation of mapk cascadeGO:00434081160.089
Human Mouse
regulation of neuron deathGO:19012141150.087
regulation of immunoglobulin productionGO:000263740.087
release of sequestered calcium ion into cytosolGO:0051209250.087
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035081970.087
positive regulation of apoptotic processGO:00430651540.087
nucleoside phosphate metabolic processGO:00067532830.087
salivary gland morphogenesisGO:000743510.087
small molecule biosynthetic processGO:00442831240.086
positive regulation of catalytic activityGO:00430851840.086
response to metal ionGO:00100382530.085
regulation of organelle organizationGO:0033043800.085
single organism carbohydrate metabolic processGO:00447231180.085
organophosphate metabolic processGO:00196373700.084
negative regulation of metabolic processGO:00098923310.084
Human Mouse
positive regulation of protein kinase activityGO:0045860730.084
single organism biosynthetic processGO:00447113420.083
nucleotide catabolic processGO:00091661390.083
myeloid leukocyte activationGO:0002274360.082
positive regulation of cell proliferationGO:00082842490.082
Human
regulation of protein complex assemblyGO:0043254330.081
ribonucleoside triphosphate catabolic processGO:00092031220.080
actin filament based processGO:0030029860.079
positive regulation of nucleobase containing compound metabolic processGO:00459353190.079
glycosyl compound catabolic processGO:19016581260.078
response to external biotic stimulusGO:00432072210.078
lipid biosynthetic processGO:00086101280.077
purine nucleoside metabolic processGO:00422781690.077
cellular component assemblyGO:00226073600.077
histamine secretion involved in inflammatory responseGO:000244130.077
dephosphorylationGO:0016311980.077
Human Mouse Rat Fly
negative regulation of signalingGO:00230571570.076
Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459341530.076
positive regulation of gene expressionGO:00106282440.076
monocarboxylic acid metabolic processGO:00327871520.076
negative regulation of homeostatic processGO:0032845470.075
Mouse
establishment of organelle localizationGO:0051656370.074
regulation of molecular functionGO:00650093980.072
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.072
Fly
ribonucleoside triphosphate metabolic processGO:00091991410.071
positive regulation of biosynthetic processGO:00098913190.070
actin filament bundle assemblyGO:0051017190.070
cell type specific apoptotic processGO:00972851340.070
regulation of intracellular signal transductionGO:19025312180.070
Human Mouse
actin cytoskeleton organizationGO:0030036730.069
ribose phosphate metabolic processGO:00196932350.069
carbohydrate derivative metabolic processGO:19011353460.069
protein localizationGO:00081041910.069
positive regulation of signalingGO:00230562700.068
Human
positive regulation of purine nucleotide metabolic processGO:1900544910.068
positive regulation of protein serine threonine kinase activityGO:0071902520.068
cell cell signalingGO:00072673350.068
calcium ion transportGO:00068161310.067
Mouse
neuron deathGO:00709971270.067
response to nutrient levelsGO:00316673700.067
endocytosisGO:0006897840.067
Fly
negative regulation of apoptotic processGO:00430661810.066
Fly
ribonucleoside catabolic processGO:00424541260.066
programmed cell deathGO:00125013920.066
Fly
negative regulation of programmed cell deathGO:00430691830.065
Fly
purine ribonucleoside triphosphate metabolic processGO:00092051400.065
response to carbohydrateGO:00097431830.065
regulation of synaptic growth at neuromuscular junctionGO:000858210.065
positive regulation of cellular biosynthetic processGO:00313282950.064
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.064
immune response regulating cell surface receptor signaling pathwayGO:0002768100.064
Mouse
ribonucleotide catabolic processGO:00092611360.064
nucleotide metabolic processGO:00091172790.064
positive regulation of neurogenesisGO:00507691650.063
cellular catabolic processGO:00442482950.063
purine ribonucleotide catabolic processGO:00091541360.063
peptidyl tyrosine phosphorylationGO:0018108720.063
Human Mouse
regulation of b cell mediated immunityGO:000271220.063
Mouse
response to peptideGO:19016522920.062
regulation of system processGO:00440572080.062
positive regulation of macromolecule biosynthetic processGO:00105572470.061
lipid metabolic processGO:00066292830.060
positive regulation of programmed cell deathGO:00430681570.060
positive regulation of cell communicationGO:00106472710.060
Human
response to inorganic substanceGO:00100353770.060
leukocyte activation involved in immune responseGO:0002366160.059
cell morphogenesis involved in neuron differentiationGO:00486671060.059
response to insulinGO:00328681330.059
immunoglobulin mediated immune responseGO:001606440.059
Mouse
positive regulation of response to stimulusGO:00485842850.059
Human Mouse
cellular response to nitrogen compoundGO:19016992100.059
cellular calcium ion homeostasisGO:00068741600.058
Mouse
dna metabolic processGO:0006259960.058
regulation of rna biosynthetic processGO:20011413810.058
Fly
ribonucleotide metabolic processGO:00092592310.058
regulation of cell activationGO:0050865500.058
Mouse
cellular response to lipopolysaccharideGO:0071222550.058
apoptotic signaling pathwayGO:0097190270.058
cellular nitrogen compound catabolic processGO:00442701630.057
cell projection morphogenesisGO:00488581230.057
cellular amine metabolic processGO:0044106380.057
positive regulation of cytoskeleton organizationGO:0051495260.057
regulation of nervous system developmentGO:00519602640.057
Fly
organophosphate catabolic processGO:00464341480.057
negative regulation of protein phosphorylationGO:0001933440.057
Human Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.057
mitotic spindle organizationGO:000705220.057
positive regulation of rna metabolic processGO:00512542030.056
cell part morphogenesisGO:00329901230.056
neuron differentiationGO:00301823680.055
Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.055
Fly
positive regulation of developmental processGO:00510942830.055
cellular response to oxygen containing compoundGO:19017013860.055
activation of protein kinase activityGO:0032147470.054
positive regulation of molecular functionGO:00440932300.054
regulation of muscle contractionGO:0006937530.054
positive regulation of protein metabolic processGO:00512471780.054
positive regulation of protein phosphorylationGO:00019341350.053
regulation of growthGO:00400081050.052
ion homeostasisGO:00508012120.052
Mouse
regulation of cell cycleGO:0051726730.052
Human
regulation of cellular component biogenesisGO:0044087860.052
exocytosisGO:0006887600.052
carbohydrate derivative catabolic processGO:19011361470.052
maintenance of locationGO:0051235170.052
negative regulation of neuron deathGO:1901215690.051
regulation of transferase activityGO:00513381230.051
Mouse
cellular response to organonitrogen compoundGO:00714171970.051
intracellular transportGO:00469071850.051
Mouse
regulation of actin filament based processGO:0032970420.051
regulation of purine nucleotide metabolic processGO:19005421150.051
cellular carbohydrate metabolic processGO:0044262720.051
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.050
response to extracellular stimulusGO:00099913800.050
lymphocyte activation involved in immune responseGO:000228530.050
positive regulation of transcription dna templatedGO:00458931970.049
cellular ketone metabolic processGO:0042180510.049
positive regulation of protein modification processGO:00314011420.049
cell morphogenesisGO:00009021420.049
Mouse
regulation of cell migrationGO:00303341280.049
positive regulation of isotype switchingGO:004583010.049
regulation of anatomical structure sizeGO:00900661350.049
cytosolic calcium ion transportGO:0060401390.049
Mouse
central nervous system developmentGO:00074173110.048
Fly
regulation of multicellular organismal developmentGO:20000263760.048
Mouse Fly
single organism reproductive processGO:00447022970.048
Fly
regulation of map kinase activityGO:0043405530.048
Mouse
organic substance catabolic processGO:19015753160.048
regulation of neurogenesisGO:00507672470.048
Fly
olfactory learningGO:000835510.048
organelle localizationGO:0051640550.048
multicellular organism reproductionGO:00325042330.048
Fly
response to bacteriumGO:00096172000.047
catabolic processGO:00090563510.047
purine nucleoside catabolic processGO:00061521240.047
signal releaseGO:00230611450.046
positive regulation of signal transductionGO:00099671750.046
Human
organic cyclic compound catabolic processGO:19013611750.046
cell projection organizationGO:00300303020.046
negative regulation of cell matrix adhesionGO:000195330.045
regulation of lymphocyte proliferationGO:0050670260.045
Mouse
positive regulation of intracellular signal transductionGO:19025331380.045
Human
cellular lipid metabolic processGO:00442552080.044
response to ketoneGO:19016541820.044
negative regulation of phosphate metabolic processGO:0045936800.044
Human Mouse
regulation of cell developmentGO:00602842630.044
Fly
positive regulation of cellular protein metabolic processGO:00322701670.044
cellular response to stressGO:00335542690.044
actin filament organizationGO:0007015420.044
glycosyl compound metabolic processGO:19016571820.044
protein transportGO:00150311320.043
regulation of nucleotide metabolic processGO:00061401170.043
organonitrogen compound catabolic processGO:19015651790.043
negative regulation of gene expressionGO:00106291990.043
hexose metabolic processGO:0019318580.043
regulation of vesicle mediated transportGO:0060627810.042
negative regulation of nucleic acid templated transcriptionGO:19035071170.042
antigen receptor mediated signaling pathwayGO:005085110.042
Mouse
brain developmentGO:00074202470.042
positive regulation of organelle organizationGO:0010638480.042
multicellular organismal reproductive processGO:00486092330.042
Fly
olfactory behaviorGO:004204820.042
negative regulation of immune system processGO:0002683390.041
Mouse
cellular homeostasisGO:00197252520.041
Mouse
regulation of signal transductionGO:00099663180.041
Human Mouse
salivary gland developmentGO:000743130.040
locomotionGO:00400112370.040
Fly
neurological system processGO:00508772190.040
lymphocyte proliferationGO:0046651290.040
Mouse
cellular response to external stimulusGO:00714961180.040
multi organism reproductive processGO:00447032620.040
Fly
single organism catabolic processGO:00447122830.040
single organism intracellular transportGO:19025821660.039
Mouse
organelle assemblyGO:0070925220.039
positive regulation of nervous system developmentGO:00519621780.039
regulation of sequestering of calcium ionGO:0051282260.039
Mouse
cellular amino acid metabolic processGO:00065201070.039
chemosensory behaviorGO:000763520.038
positive regulation of hydrolase activityGO:0051345860.038
immune effector processGO:0002252530.038
Mouse
negative regulation of transcription dna templatedGO:00458921160.038
peptidyl amino acid modificationGO:00181931260.038
Human Mouse
nucleoside catabolic processGO:00091641260.038
negative regulation of rna metabolic processGO:00512531230.038
heterocycle catabolic processGO:00467001670.038
signal transduction in absence of ligandGO:003803450.038
actin filament based movementGO:0030048160.038
nitrogen compound transportGO:00717052290.037
negative regulation of rna biosynthetic processGO:19026791180.037
calcium ion homeostasisGO:00550741620.037
Mouse
tissue developmentGO:00098882520.037
Fly
regulation of protein transportGO:0051223680.037
regulation of nucleotide catabolic processGO:0030811650.037
regulation of secretionGO:00510462240.037
neuron projection morphogenesisGO:00488121220.036
fc receptor mediated stimulatory signaling pathwayGO:000243130.036
neurotrophin signaling pathwayGO:0038179180.036
carbohydrate metabolic processGO:00059751300.036
nucleobase containing compound catabolic processGO:00346551520.036
positive regulation of cell motilityGO:2000147970.035
response to acid chemicalGO:00011012220.035
positive regulation of platelet derived growth factor receptor signaling pathwayGO:001064110.035
axonogenesisGO:0007409710.035
response to nutrientGO:00075842480.035
purine nucleoside triphosphate catabolic processGO:00091461220.035
positive regulation of phosphorylationGO:00423271770.035
regulation of cellular amino acid metabolic processGO:000652120.035
regulation of intracellular transportGO:0032386650.035
Mouse
secretion by cellGO:00329402480.035
leukocyte homeostasisGO:000177670.035
purine containing compound catabolic processGO:00725231380.035
positive regulation of cell differentiationGO:00455972170.034
response to phGO:0009268270.034
regulation of secretion by cellGO:19035302080.034
sequestering of metal ionGO:005123890.034
cell cell junction assemblyGO:000704370.034
histamine production involved in inflammatory responseGO:000234930.034
response to oxygen levelsGO:00704822650.034
negative regulation of macromolecule biosynthetic processGO:00105581480.034
metal ion homeostasisGO:00550651860.034
Mouse
t cell activationGO:0042110290.034
Mouse
regulation of protein localizationGO:0032880810.033
muscle cell migrationGO:0014812360.033
macromolecule localizationGO:00330362520.033
positive regulation of mapk cascadeGO:0043410920.033
cellular component morphogenesisGO:00329891550.033
Mouse
calcium ion transport into cytosolGO:0060402380.033
Mouse
regulation of purine nucleotide catabolic processGO:0033121650.033
regulation of immune system processGO:00026821230.033
Mouse
regulation of calcium ion transport into cytosolGO:0010522250.033
Mouse
developmental process involved in reproductionGO:00030061590.032
Fly
cellular chemical homeostasisGO:00550822470.032
Mouse
regulation of dna metabolic processGO:0051052600.032
growthGO:00400071650.032
purine ribonucleoside catabolic processGO:00461301240.032
regulation of protein serine threonine kinase activityGO:0071900640.032
Mouse
regulation of muscle system processGO:0090257790.032
negative regulation of neuron apoptotic processGO:0043524450.032
regulation of b cell differentiationGO:004557710.032
Mouse
establishment of protein localizationGO:00451841410.032
regulation of arp2 3 complex mediated actin nucleationGO:003431520.032
nucleoside monophosphate metabolic processGO:0009123930.031
regulation of hormone levelsGO:00108171870.031
cell motilityGO:00488702020.031
Fly
regulation of kinase activityGO:00435491170.031
Mouse
purine nucleoside triphosphate metabolic processGO:00091441410.031
response to molecule of bacterial originGO:00022371940.031
cytoplasmic transportGO:00164821150.031
Mouse
negative regulation of cell deathGO:00605482290.031
Fly
b cell differentiationGO:003018320.031
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123950.031
hormone transportGO:00099141210.031
leukocyte degranulationGO:0043299120.030
reproductive processGO:00224143720.030
Fly
negative regulation of sequestering of calcium ionGO:0051283250.030
Mouse
negative regulation of cellular component organizationGO:0051129830.030
response to decreased oxygen levelsGO:00362932370.030
negative regulation of macromolecule metabolic processGO:00106052600.030
Human Mouse
glucose metabolic processGO:0006006520.030
defense response to gram positive bacteriumGO:005083020.030
regulation of immune responseGO:0050776550.030
Mouse
negative regulation of biosynthetic processGO:00098901680.029
response to hypoxiaGO:00016662310.029
nucleoside phosphate catabolic processGO:19012921400.029
response to fatty acidGO:0070542650.029
divalent metal ion transportGO:00708381320.029
Mouse
regulation of carbohydrate metabolic processGO:0006109410.028
positive regulation of cell developmentGO:00107201760.028
negative regulation of cellular biosynthetic processGO:00313271610.028
positive regulation of nucleotide metabolic processGO:0045981910.028
gland developmentGO:00487321550.028
positive regulation of leukocyte proliferationGO:0070665200.028
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.028
response to purine containing compoundGO:00140741260.028
actin polymerization or depolymerizationGO:0008154140.028
negative regulation of insulin receptor signaling pathwayGO:0046627100.028
muscle system processGO:00030121150.027
positive regulation of map kinase activityGO:0043406460.027
spindle organizationGO:000705120.027
negative regulation of protein modification processGO:0031400520.027
Human Mouse
positive regulation of dna metabolic processGO:0051054390.027
cellular protein complex assemblyGO:0043623440.027
regulation of actin cytoskeleton organizationGO:0032956300.027
cellular response to molecule of fungal originGO:007122610.027
regulation of mononuclear cell proliferationGO:0032944260.027
Mouse
negative regulation of nervous system developmentGO:0051961790.027
regulation of cellular component sizeGO:0032535510.027
organic hydroxy compound metabolic processGO:19016151150.027
biological adhesionGO:00226101100.027
Mouse
regulation of cell morphogenesisGO:0022604770.026
divalent inorganic cation transportGO:00725111340.026
Mouse
neuron developmentGO:00486662860.026
Fly
axis specificationGO:000979840.026
Fly
lysosome localizationGO:0032418100.026
hematopoietic progenitor cell differentiationGO:000224420.026
Mouse
regulation of leukocyte proliferationGO:0070663260.026
Mouse
gastrulationGO:000736920.026
monosaccharide metabolic processGO:0005996610.025
positive regulation of kinase activityGO:0033674770.025
negative regulation of cellular response to insulin stimulusGO:1900077110.025
nucleoside metabolic processGO:00091161790.025
cell adhesionGO:00071551100.025
Mouse
regulation of hydrolase activityGO:00513361430.025
axon developmentGO:0061564960.025
regulation of cellular response to insulin stimulusGO:1900076160.025
reproductionGO:00000032450.024
Fly
protein heterooligomerizationGO:0051291890.024
head developmentGO:00603222470.024
single organism behaviorGO:00447081300.024
regulation of establishment of protein localizationGO:0070201690.024
cell cycle processGO:0022402570.024
Human
arp2 3 complex mediated actin nucleationGO:003431420.024
programmed necrotic cell deathGO:009730020.024
cellular process involved in reproduction in multicellular organismGO:0022412350.024
Fly
cell cell junction organizationGO:0045216200.024
positive regulation of transferase activityGO:0051347810.023
ribonucleoside metabolic processGO:00091191740.023
purine ribonucleoside monophosphate catabolic processGO:0009169550.023
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.023
regulation of cellular catabolic processGO:00313291010.023
negative regulation of developmental processGO:00510931250.023
t cell proliferationGO:0042098190.023
Mouse
hormone secretionGO:00468791150.023
cellular response to hormone stimulusGO:00328702470.022
regulation of catabolic processGO:00098941130.022
cellular response to reactive oxygen speciesGO:0034614550.022
small gtpase mediated signal transductionGO:0007264360.022
transcription from rna polymerase ii promoterGO:00063662520.022
Fly
regulation of immunoglobulin mediated immune responseGO:000288920.022
Mouse
regulation of homeostatic processGO:00328441010.022
Mouse
agingGO:00075682410.022
activation of protein kinase b activityGO:003214830.022
nucleoside triphosphate metabolic processGO:00091411440.022
regulation of cell differentiationGO:00455953200.022
Mouse Fly
cellular macromolecular complex assemblyGO:0034622580.022
sexual reproductionGO:00199531480.022
Fly
regulation of apoptotic signaling pathwayGO:2001233130.022
positive regulation of multicellular organismal processGO:00512403870.021
phospholipid metabolic processGO:0006644610.021
skeletal system developmentGO:0001501410.021
positive regulation of protein secretionGO:0050714190.021
intracellular receptor signaling pathwayGO:0030522350.021
negative regulation of molecular functionGO:00440921330.021
Mouse
regulation of neuron differentiationGO:00456642080.021
Fly
response to axon injuryGO:0048678590.021
regulation of lipid metabolic processGO:0019216680.021
phosphatidylinositol 3 kinase signalingGO:0014065140.020
Human
cellular response to mechanical stimulusGO:0071260480.020
single organism cellular localizationGO:19025801020.020
negative regulation of protein metabolic processGO:00512481140.020
Human Mouse
protein polymerizationGO:0051258220.020
formation of primary germ layerGO:000170410.020
activation of immune responseGO:0002253260.020
Mouse
positive regulation of secretionGO:00510471400.020
regulation of neural precursor cell proliferationGO:2000177160.020
muscle contractionGO:0006936880.020
mast cell degranulationGO:0043303100.020
response to mineralocorticoidGO:0051385490.020
negative regulation of cellular protein metabolic processGO:00322691060.020
Human Mouse
localization of cellGO:00516742020.020
Fly
lymphocyte homeostasisGO:000226020.020
ribonucleoside monophosphate metabolic processGO:0009161880.020
regulation of actin polymerization or depolymerizationGO:0008064120.019
learningGO:0007612330.019
negative regulation of signal transduction in absence of ligandGO:190109930.019
response to cytokineGO:00340972150.019
regulation of cellular ketone metabolic processGO:0010565270.019
peptidyl serine phosphorylationGO:0018105330.019
organic acid biosynthetic processGO:0016053830.019
negative regulation of transportGO:00510511360.019
positive regulation of cellular amine metabolic processGO:003324030.019
leukocyte proliferationGO:0070661290.019
Mouse
nucleoside monophosphate catabolic processGO:0009125560.019
response to amino acidGO:0043200750.019
regulation of cellular extravasationGO:000269120.019
response to monosaccharideGO:00342841590.018
peptidyl serine modificationGO:0018209340.018
amine metabolic processGO:0009308380.018
regulation of locomotionGO:00400121480.018
monocarboxylic acid biosynthetic processGO:0072330480.018
peptidyl tyrosine modificationGO:0018212720.018
Human Mouse
regenerationGO:00310991630.018
regulation of cellular amine metabolic processGO:003323880.018
positive regulation of erk1 and erk2 cascadeGO:0070374290.018
myeloid cell activation involved in immune responseGO:0002275130.018
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.018
negative regulation of multicellular organismal processGO:00512412030.018
positive regulation of isotype switching to igg isotypesGO:004830410.018
leukocyte cell cell adhesionGO:000715940.018

Ptpn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.035
primary immunodeficiency diseaseDOID:61200.035
disease of anatomical entityDOID:700.035
hematopoietic system diseaseDOID:7400.018
blood protein diseaseDOID:62000.018