Rattus norvegicus

0 known processes

Ptpn5

protein tyrosine phosphatase, non-receptor type 5

(Aliases: STEP)

Ptpn5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid transportGO:00158491160.184
synaptic transmissionGO:00072682350.184
cell cell signalingGO:00072673350.131
neuron differentiationGO:00301823680.116
Rat Fly
anion transportGO:00068201780.108
transmembrane transportGO:00550854120.103
nucleobase containing small molecule metabolic processGO:00550863160.090
ion transmembrane transportGO:00342203650.088
glutamate receptor signaling pathwayGO:0007215430.088
ion homeostasisGO:00508012120.086
protein complex subunit organizationGO:00718223020.086
regulation of cellular component organizationGO:00511283680.085
inorganic cation transmembrane transportGO:00986622020.081
cellular component assemblyGO:00226073600.081
response to alkaloidGO:00432791320.079
carboxylic acid transportGO:00469421150.079
lipid metabolic processGO:00066292830.077
response to temperature stimulusGO:0009266940.077
ionotropic glutamate receptor signaling pathwayGO:0035235340.073
amino acid transportGO:0006865700.070
response to estrogenGO:00436272320.069
cation homeostasisGO:00550801950.069
blood circulationGO:00080151830.068
cellular chemical homeostasisGO:00550822470.067
regulation of saliva secretionGO:004687730.066
organic anion transportGO:00157111320.066
g protein coupled receptor signaling pathwayGO:00071862420.066
regulation of ion transportGO:00432692450.064
cellular component biogenesisGO:00440853680.062
rna metabolic processGO:00160704060.061
single organism behaviorGO:00447081300.061
cellular calcium ion homeostasisGO:00068741600.060
cellular response to hormone stimulusGO:00328702470.058
macromolecular complex subunit organizationGO:00439333390.056
response to corticosteroidGO:00319602350.056
organophosphate metabolic processGO:00196373700.056
metal ion transportGO:00300012890.056
cellular response to steroid hormone stimulusGO:0071383930.055
anatomical structure morphogenesisGO:00096532980.055
Fly
response to toxic substanceGO:00096361330.053
transcription dna templatedGO:00063513770.052
organelle organizationGO:00069962660.052
cellular response to stressGO:00335542690.052
response to amineGO:0014075460.052
secretionGO:00469033070.051
chemical homeostasisGO:00488782920.051
cation transportGO:00068123820.050
organonitrogen compound catabolic processGO:19015651790.050
circulatory system processGO:00030131830.049
membrane organizationGO:0061024940.049
response to peptideGO:19016522920.049
cellular catabolic processGO:00442482950.049
response to extracellular stimulusGO:00099913800.049
response to ketoneGO:19016541820.046
response to oxygen levelsGO:00704822650.046
intracellular signal transductionGO:00355563140.045
Fly
nucleic acid templated transcriptionGO:00976593790.045
divalent metal ion transportGO:00708381320.045
regulation of blood circulationGO:19035221100.045
catabolic processGO:00090563510.044
response to glucocorticoidGO:00513842230.043
negative regulation of cell communicationGO:00106481580.043
Fly
ribonucleotide metabolic processGO:00092592310.043
cellular response to endogenous stimulusGO:00714953770.043
adult locomotory behaviorGO:000834440.042
calcium ion homeostasisGO:00550741620.042
synaptic growth at neuromuscular junctionGO:005112410.041
cellular ion homeostasisGO:00068731840.041
cellular divalent inorganic cation homeostasisGO:00725031620.041
response to inorganic substanceGO:00100353770.041
regulation of postsynaptic membrane potentialGO:0060078250.040
response to nutrient levelsGO:00316673700.040
telencephalon developmentGO:0021537620.040
cellular homeostasisGO:00197252520.039
action potentialGO:0001508540.039
negative regulation of cellular metabolic processGO:00313242810.039
Fly
regulation of synaptic transmissionGO:00508041410.038
cellular lipid metabolic processGO:00442552080.038
multicellular organism reproductionGO:00325042330.038
metal ion homeostasisGO:00550651860.037
nucleoside phosphate metabolic processGO:00067532830.037
calcium ion transportGO:00068161310.037
negative regulation of signalingGO:00230571570.036
Fly
respiratory gaseous exchangeGO:000758540.036
regulation of vesicle mediated transportGO:0060627810.035
sensory perceptionGO:00076001010.035
positive regulation of cytosolic calcium ion concentrationGO:00072041220.034
protein complex biogenesisGO:00702712630.034
glycerolipid metabolic processGO:0046486670.034
positive regulation of signal transductionGO:00099671750.034
vesicle mediated transportGO:00161921810.034
regenerationGO:00310991630.033
somatostatin signaling pathwayGO:003817040.033
macromolecule localizationGO:00330362520.033
rna biosynthetic processGO:00327743800.032
multi organism reproductive processGO:00447032620.032
intracellular transportGO:00469071850.032
regulation of cellular localizationGO:00603412630.032
response to estradiolGO:00323551640.032
cellular response to organic cyclic compoundGO:00714072020.032
regulation of transcription dna templatedGO:00063553740.032
negative regulation of response to stimulusGO:00485851550.031
Fly
response to hypoxiaGO:00016662310.031
regulation of multicellular organismal developmentGO:20000263760.031
divalent inorganic cation homeostasisGO:00725071650.031
negative regulation of metabolic processGO:00098923310.030
Fly
response to insulinGO:00328681330.030
vesicle localizationGO:0051648330.030
regulation of membrane potentialGO:00423911100.029
sexual reproductionGO:00199531480.029
dicarboxylic acid transportGO:0006835340.029
neuron apoptotic processGO:0051402880.029
organic substance catabolic processGO:19015753160.029
neuron projection developmentGO:00311752730.029
neuromuscular processGO:005090520.029
response to metal ionGO:00100382530.028
cation transmembrane transportGO:00986552630.028
positive regulation of nucleotide metabolic processGO:0045981910.028
regulation of hydrolase activityGO:00513361430.028
forebrain developmentGO:0030900980.028
response to radiationGO:00093141370.028
regulation of molecular functionGO:00650093980.027
regulation of blood pressureGO:0008217830.027
cellular cation homeostasisGO:00300031800.027
peptide hormone secretionGO:0030072840.027
response to mechanical stimulusGO:00096121340.027
nucleotide metabolic processGO:00091172790.027
regulation of respiratory gaseous exchangeGO:004357620.027
regulation of synaptic vesicle recyclingGO:190342110.027
cellular response to estradiol stimulusGO:0071392160.027
protein complex assemblyGO:00064612630.027
positive regulation of macromolecule biosynthetic processGO:00105572470.026
regulation of apoptotic processGO:00429813350.026
oxoacid metabolic processGO:00434362900.026
positive regulation of protein serine threonine kinase activityGO:0071902520.026
protein oligomerizationGO:00512591910.026
response to decreased oxygen levelsGO:00362932370.026
positive regulation of apoptotic processGO:00430651540.025
macromolecular complex assemblyGO:00650032730.025
cellular nitrogen compound catabolic processGO:00442701630.025
negative regulation of cellular biosynthetic processGO:00313271610.025
response to monosaccharideGO:00342841590.025
homeostatic processGO:00425923310.025
transcription from rna polymerase ii promoterGO:00063662520.025
cardiac chamber developmentGO:000320510.025
calcium ion transmembrane transportGO:0070588700.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
negative regulation of transportGO:00510511360.025
reproductive processGO:00224143720.025
nitrogen compound transportGO:00717052290.025
regulation of response to external stimulusGO:00321011060.025
single organism reproductive processGO:00447022970.024
response to peptide hormoneGO:00434342780.024
associative learningGO:0008306190.024
somatostatin receptor signaling pathwayGO:003816940.024
head developmentGO:00603222470.024
regulation of system processGO:00440572080.024
proteolysisGO:00065081750.024
muscle system processGO:00030121150.024
nucleoside phosphate biosynthetic processGO:19012931020.024
central nervous system developmentGO:00074173110.023
carbohydrate derivative metabolic processGO:19011353460.023
secretion by cellGO:00329402480.023
neuron deathGO:00709971270.023
positive regulation of response to stimulusGO:00485842850.023
positive regulation of catalytic activityGO:00430851840.023
regulation of cell differentiationGO:00455953200.023
rhythmic processGO:00485111560.023
cellular response to extracellular stimulusGO:0031668730.023
positive regulation of multicellular organismal processGO:00512403870.023
cell cycleGO:00070491010.023
Fly
cell morphogenesisGO:00009021420.022
glycosyl compound catabolic processGO:19016581260.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
gtp metabolic processGO:0046039720.022
phasic smooth muscle contractionGO:001482130.022
response to transition metal nanoparticleGO:19902671220.022
protein transportGO:00150311320.022
carboxylic acid metabolic processGO:00197522890.022
response to osmotic stressGO:0006970420.022
neurological system processGO:00508772190.022
response to heatGO:0009408600.022
cellular response to oxygen containing compoundGO:19017013860.021
positive regulation of biosynthetic processGO:00098913190.021
regulation of locomotionGO:00400121480.021
detection of calcium ionGO:000551310.021
regulation of cell projection organizationGO:00313441750.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
organophosphate catabolic processGO:00464341480.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
regulation of ion transmembrane transporter activityGO:0032412480.021
ribose phosphate metabolic processGO:00196932350.021
regulation of neurogenesisGO:00507672470.021
lipid modificationGO:0030258520.021
regulation of intracellular signal transductionGO:19025312180.021
Fly
single organism biosynthetic processGO:00447113420.021
regulation of rna metabolic processGO:00512523910.021
cellular metal ion homeostasisGO:00068751720.021
learningGO:0007612330.021
monovalent inorganic cation transportGO:00156721720.021
negative regulation of macromolecule metabolic processGO:00106052600.020
regulation of neuronal synaptic plasticityGO:0048168310.020
regulation of neuron projection developmentGO:00109751610.020
regulation of organic acid transportGO:0032890350.020
inorganic ion transmembrane transportGO:00986602290.020
circulatory system developmentGO:00723591340.020
regulation of cell morphogenesis involved in differentiationGO:0010769720.020
cyclic nucleotide metabolic processGO:0009187800.020
purine containing compound metabolic processGO:00725212530.020
regulation of anion transportGO:0044070430.020
regulation of cellular protein metabolic processGO:00322682670.020
organic acid metabolic processGO:00060822920.019
regulation of catalytic activityGO:00507903040.019
response to ethanolGO:00454711620.019
positive regulation of programmed cell deathGO:00430681570.019
protein homooligomerizationGO:0051260910.019
acid secretionGO:0046717480.019
programmed cell deathGO:00125013920.019
actin filament organizationGO:0007015420.019
regulation of signal transductionGO:00099663180.019
Fly
phospholipid metabolic processGO:0006644610.019
heart morphogenesisGO:000300730.019
response to woundingGO:00096112540.019
smooth muscle contractionGO:0006939370.019
positive regulation of secretionGO:00510471400.019
regulation of tube sizeGO:0035150890.019
response to starvationGO:0042594590.019
regulation of catabolic processGO:00098941130.019
response to growth factorGO:00708481890.019
response to amphetamineGO:0001975250.019
negative regulation of cellular component organizationGO:0051129830.019
peristalsisGO:003043220.019
positive regulation of phosphorus metabolic processGO:00105622620.018
amine transportGO:0015837570.018
response to external biotic stimulusGO:00432072210.018
positive regulation of developmental processGO:00510942830.018
regulation of organelle organizationGO:0033043800.018
reproductionGO:00000032450.018
organic cyclic compound catabolic processGO:19013611750.018
small molecule biosynthetic processGO:00442831240.018
regulation of programmed cell deathGO:00430673410.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
nucleobase containing compound catabolic processGO:00346551520.018
organophosphate biosynthetic processGO:00904071430.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
positive regulation of synaptic vesicle recyclingGO:190342310.017
ribonucleotide biosynthetic processGO:0009260850.017
brain developmentGO:00074202470.017
cell projection morphogenesisGO:00488581230.017
cellular response to nitrogen compoundGO:19016992100.017
cellular response to peptideGO:19016531330.017
synaptic vesicle amine transportGO:001584230.017
cellular component movementGO:00069282480.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
single organism organelle organizationGO:19025891800.017
cellular response to corticosteroid stimulusGO:0071384690.017
regulation of purine nucleotide metabolic processGO:19005421150.017
muscle contractionGO:0006936880.017
regulation of secretion by cellGO:19035302080.016
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.016
actin filament based processGO:0030029860.016
dendrite developmentGO:0016358720.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.016
cytosolic calcium ion homeostasisGO:00514801400.016
purine nucleotide metabolic processGO:00061632290.016
cyclic purine nucleotide metabolic processGO:0052652620.016
purine nucleoside catabolic processGO:00061521240.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
regulation of rna biosynthetic processGO:20011413810.016
nucleoside triphosphate metabolic processGO:00091411440.016
establishment of vesicle localizationGO:0051650310.016
cellular response to alcoholGO:0097306870.016
cellular response to growth factor stimulusGO:00713631620.016
positive regulation of cell deathGO:00109421840.015
multi multicellular organism processGO:00447061380.015
regulation of amino acid transportGO:0051955250.015
cell part morphogenesisGO:00329901230.015
signal transduction by phosphorylationGO:00230141440.015
Fly
defecationGO:003042110.015
chemosensory behaviorGO:000763520.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
phosphatidylinositol dephosphorylationGO:004685640.015
carbohydrate derivative biosynthetic processGO:19011371240.015
ribose phosphate biosynthetic processGO:0046390870.015
response to calcium ionGO:0051592590.015
positive regulation of transcription dna templatedGO:00458931970.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
response to ammonium ionGO:0060359710.015
glycerophospholipid metabolic processGO:0006650470.015
positive regulation of cellular biosynthetic processGO:00313282950.015
positive regulation of secretion by cellGO:19035321280.015
organelle localizationGO:0051640550.015
endocytosisGO:0006897840.015
regulation of phosphate metabolic processGO:00192203490.015
Fly
amine metabolic processGO:0009308380.015
regulation of ion transmembrane transportGO:00347651210.015
agingGO:00075682410.015
wound healingGO:00420601220.015
limb morphogenesisGO:003510840.014
regulation of transmembrane transportGO:00347621220.014
response to morphineGO:0043278270.014
regulation of cellular component biogenesisGO:0044087860.014
regulation of cellular catabolic processGO:00313291010.014
saliva secretionGO:004654130.014
regulation of cell proliferationGO:00421273590.014
mapk cascadeGO:00001651400.014
Fly
single organism catabolic processGO:00447122830.014
gamete generationGO:00072761240.014
positive regulation of rna biosynthetic processGO:19026801970.014
embryonic appendage morphogenesisGO:003511340.014
regulation of nucleotide metabolic processGO:00061401170.014
heterocycle catabolic processGO:00467001670.014
response to oxidative stressGO:00069791860.014
neuron developmentGO:00486662860.014
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.014
smooth muscle cell proliferationGO:0048659770.014
cellular response to glucocorticoid stimulusGO:0071385680.014
purine containing compound biosynthetic processGO:0072522850.013
cellular response to external stimulusGO:00714961180.013
multicellular organismal reproductive processGO:00486092330.013
presynaptic membrane assemblyGO:009710530.013
developmental growthGO:00485891000.013
cyclic nucleotide biosynthetic processGO:0009190630.013
negative regulation of biosynthetic processGO:00098901680.013
negative regulation of phosphorus metabolic processGO:0010563800.013
Fly
positive regulation of molecular functionGO:00440932300.013
positive regulation of cell proliferationGO:00082842490.013
regulation of excitatory postsynaptic membrane potentialGO:0060079180.013
activation of cysteine type endopeptidase activityGO:009720240.013
male mating behaviorGO:006017930.013
growthGO:00400071650.013
response to carbohydrateGO:00097431830.013
olfactory learningGO:000835510.013
regulation of smooth muscle cell proliferationGO:0048660750.013
single organism intracellular transportGO:19025821660.013
purine containing compound catabolic processGO:00725231380.013
regulation of cell cycleGO:0051726730.013
divalent inorganic cation transportGO:00725111340.013
positive regulation of intracellular signal transductionGO:19025331380.013
cytoskeleton organizationGO:00070101110.013
detection of stimulusGO:0051606240.013
developmental process involved in reproductionGO:00030061590.013
positive regulation of dendritic spine developmentGO:006099990.013
startle responseGO:000196420.013
response to coldGO:0009409290.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.013
negative regulation of molecular functionGO:00440921330.012
gliogenesisGO:0042063930.012
positive regulation of signalingGO:00230562700.012
cellular response to metal ionGO:0071248550.012
apoptotic processGO:00069153810.012
cellular component morphogenesisGO:00329891550.012
positive regulation of saliva secretionGO:004687830.012
defense responseGO:00069521940.012
response to manganese ionGO:0010042130.012
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.012
regulation of heart contractionGO:0008016480.012
regulation of homeostatic processGO:00328441010.012
organonitrogen compound biosynthetic processGO:19015661670.012
single organism cellular localizationGO:19025801020.012
regulation of nervous system developmentGO:00519602640.012
cellular amino acid metabolic processGO:00065201070.012
lipid biosynthetic processGO:00086101280.012
limbic system developmentGO:0021761380.012
steroid hormone mediated signaling pathwayGO:004340180.012
feeding behaviorGO:0007631530.012
cardiac muscle cell contractionGO:0086003100.012
purine ribonucleotide biosynthetic processGO:0009152810.012
response to fluorideGO:190261730.012
regulation of neurotransmitter levelsGO:0001505420.012
regulation of cellular component movementGO:00512701500.012
heart processGO:0003015570.012
response to foodGO:0032094270.012
cell cycle checkpointGO:000007520.011
cellular response to nutrient levelsGO:0031669600.011
regulation of developmental growthGO:0048638450.011
positive regulation of transportGO:00510502450.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
regulation of protein localizationGO:0032880810.011
gastrulationGO:000736920.011
cellular response to alkaloidGO:0071312250.011
ribonucleoside metabolic processGO:00091191740.011
lipid transportGO:0006869610.011
response to electrical stimulusGO:0051602560.011
renin secretion into blood streamGO:000200110.011
cardiovascular system developmentGO:00723581340.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
response to fungicideGO:0060992200.011
response to antibioticGO:0046677390.011
embryonic axis specificationGO:000057810.011
vascular process in circulatory systemGO:0003018960.011
positive regulation of cell differentiationGO:00455972170.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.011
axis specificationGO:000979840.011
negative regulation of signal transductionGO:0009968830.011
Fly
nucleotide catabolic processGO:00091661390.011
actin cytoskeleton organizationGO:0030036730.011
neurotransmitter gated ion channel clusteringGO:007257830.011
nucleotide biosynthetic processGO:0009165980.011
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057920.011
tissue remodelingGO:0048771400.011
organelle fissionGO:0048285250.011
protein phosphorylationGO:00064683450.011
response to light stimulusGO:0009416520.011
sensory perception of light stimulusGO:005095330.011
response to activityGO:0014823730.011
glutamate secretionGO:0014047190.011
response to glucoseGO:00097491360.010
response to biotic stimulusGO:00096072260.010
establishment of protein localizationGO:00451841410.010
rhythmic behaviorGO:0007622240.010
behaviorGO:00076102050.010
spindle organizationGO:000705120.010
circadian rhythmGO:0007623880.010
positive regulation of cell communicationGO:00106472710.010
pallium developmentGO:0021543420.010
purine nucleoside metabolic processGO:00422781690.010
heart contractionGO:0060047570.010
positive regulation of long term synaptic potentiationGO:190027340.010
regulation of phosphorus metabolic processGO:00511743490.010
Fly
regulation of purine nucleotide catabolic processGO:0033121650.010
acute inflammatory responseGO:0002526580.010
chromosome segregationGO:000705920.010
endoplasmic reticulum organizationGO:000702910.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
cellular amine metabolic processGO:0044106380.010
signal releaseGO:00230611450.010
positive regulation of dendritic spine morphogenesisGO:006100330.010

Ptpn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
musculoskeletal system diseaseDOID:1700.053
cardiovascular system diseaseDOID:128700.042
muscle tissue diseaseDOID:6600.020
myopathyDOID:42300.020
muscular diseaseDOID:008000000.020