Rattus norvegicus

52 known processes

Als2

amyotrophic lateral sclerosis 2 (juvenile) homolog (human)

Als2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.092
lipid metabolic processGO:00066292830.079
organic acid metabolic processGO:00060822920.066
carboxylic acid metabolic processGO:00197522890.050
regulation of programmed cell deathGO:00430673410.049
single organism biosynthetic processGO:00447113420.040
neuron differentiationGO:00301823680.039
central nervous system developmentGO:00074173110.038
intracellular signal transductionGO:00355563140.038
catabolic processGO:00090563510.033
Human Mouse
brain developmentGO:00074202470.032
programmed cell deathGO:00125013920.031
positive regulation of multicellular organismal processGO:00512403870.031
cellular lipid metabolic processGO:00442552080.030
regulation of apoptotic processGO:00429813350.029
neuron projection developmentGO:00311752730.029
regulation of cellular component organizationGO:00511283680.028
response to glucocorticoidGO:00513842230.028
head developmentGO:00603222470.028
response to metal ionGO:00100382530.028
response to inorganic substanceGO:00100353770.028
organic substance catabolic processGO:19015753160.027
Human Mouse
cellular amine metabolic processGO:0044106380.027
regulation of multicellular organismal developmentGO:20000263760.027
organelle organizationGO:00069962660.027
Human Mouse
oxidation reduction processGO:00551143040.027
cellular response to endogenous stimulusGO:00714953770.027
nucleic acid templated transcriptionGO:00976593790.026
single organism catabolic processGO:00447122830.026
Human Mouse
multicellular organism growthGO:003526410.026
positive regulation of biosynthetic processGO:00098913190.026
positive regulation of nitrogen compound metabolic processGO:00511733340.026
Human
macromolecule localizationGO:00330362520.025
Mouse
response to growth factorGO:00708481890.025
apoptotic processGO:00069153810.025
response to nutrient levelsGO:00316673700.025
cellular amino acid metabolic processGO:00065201070.025
positive regulation of cellular biosynthetic processGO:00313282950.024
regulation of signal transductionGO:00099663180.024
Human Mouse
rna metabolic processGO:00160704060.024
cell cell signalingGO:00072673350.024
Mouse
cellular response to oxygen containing compoundGO:19017013860.024
nucleobase containing small molecule metabolic processGO:00550863160.024
Human Mouse
amine metabolic processGO:0009308380.023
reproductive processGO:00224143720.023
cellular component assemblyGO:00226073600.023
regulation of cell projection organizationGO:00313441750.023
regulation of neuron projection developmentGO:00109751610.023
regulation of neurogenesisGO:00507672470.023
ion transmembrane transportGO:00342203650.023
regulation of cell differentiationGO:00455953200.023
regulation of neuron differentiationGO:00456642080.023
carbohydrate derivative metabolic processGO:19011353460.023
Human Mouse
g protein coupled receptor signaling pathwayGO:00071862420.023
cell projection organizationGO:00300303020.022
cellular response to growth factor stimulusGO:00713631620.022
positive regulation of cellular component organizationGO:00511302000.022
negative regulation of cell deathGO:00605482290.021
positive regulation of molecular functionGO:00440932300.021
Human
cation transportGO:00068123820.021
cellular response to stressGO:00335542690.021
blood circulationGO:00080151830.021
transmembrane transportGO:00550854120.021
response to purine containing compoundGO:00140741260.021
cellular component biogenesisGO:00440853680.021
organophosphate metabolic processGO:00196373700.021
Human Mouse
positive regulation of phosphate metabolic processGO:00459372620.020
Human
response to corticosteroidGO:00319602350.020
positive regulation of developmental processGO:00510942830.020
regulation of rna metabolic processGO:00512523910.020
cellular catabolic processGO:00442482950.020
Human Mouse
positive regulation of signalingGO:00230562700.020
homeostatic processGO:00425923310.020
response to ketoneGO:19016541820.020
regulation of cellular amino acid metabolic processGO:000652120.020
response to acid chemicalGO:00011012220.020
multicellular organismal reproductive processGO:00486092330.020
regulation of cell developmentGO:00602842630.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
Human
regulation of cellular amine metabolic processGO:003323880.020
positive regulation of phosphorus metabolic processGO:00105622620.020
Human
cell morphogenesis involved in neuron differentiationGO:00486671060.019
cellular chemical homeostasisGO:00550822470.019
regulation of transcription dna templatedGO:00063553740.019
chemical homeostasisGO:00488782920.019
single organism organelle organizationGO:19025891800.019
secretionGO:00469033070.019
secretion by cellGO:00329402480.019
regulation of nervous system developmentGO:00519602640.019
organonitrogen compound biosynthetic processGO:19015661670.019
cellular ketone metabolic processGO:0042180510.019
small molecule biosynthetic processGO:00442831240.019
single organism reproductive processGO:00447022970.019
positive regulation of macromolecule biosynthetic processGO:00105572470.018
neurological system processGO:00508772190.018
reproductionGO:00000032450.018
carboxylic acid biosynthetic processGO:0046394830.018
response to peptideGO:19016522920.018
regulation of system processGO:00440572080.018
regulation of phosphorus metabolic processGO:00511743490.018
Human Mouse
nitrogen compound transportGO:00717052290.018
response to peptide hormoneGO:00434342780.018
ribose phosphate metabolic processGO:00196932350.018
Human Mouse
regulation of rna biosynthetic processGO:20011413810.018
response to ethanolGO:00454711620.018
positive regulation of transportGO:00510502450.017
circulatory system processGO:00030131830.017
anatomical structure morphogenesisGO:00096532980.017
negative regulation of apoptotic processGO:00430661810.017
positive regulation of cell deathGO:00109421840.017
response to extracellular stimulusGO:00099913800.017
negative regulation of cell communicationGO:00106481580.017
protein phosphorylationGO:00064683450.017
Human
regulation of nucleic acid templated transcriptionGO:19035063800.017
nucleotide metabolic processGO:00091172790.017
Human Mouse
rna biosynthetic processGO:00327743800.017
multi organism reproductive processGO:00447032620.017
regulation of secretionGO:00510462240.017
regulation of intracellular signal transductionGO:19025312180.017
Human Mouse
positive regulation of cell proliferationGO:00082842490.017
negative regulation of metabolic processGO:00098923310.017
lipid biosynthetic processGO:00086101280.017
positive regulation of transcription dna templatedGO:00458931970.016
regulation of phosphate metabolic processGO:00192203490.016
Human Mouse
organic acid biosynthetic processGO:0016053830.016
ion homeostasisGO:00508012120.016
locomotionGO:00400112370.016
regulation of hormone levelsGO:00108171870.016
purine containing compound metabolic processGO:00725212530.016
Human Mouse
cellular homeostasisGO:00197252520.016
negative regulation of programmed cell deathGO:00430691830.016
growthGO:00400071650.016
small gtpase mediated signal transductionGO:0007264360.016
metal ion transportGO:00300012890.016
positive regulation of catalytic activityGO:00430851840.016
Human
response to oxidative stressGO:00069791860.016
Mouse
positive regulation of gene expressionGO:00106282440.016
positive regulation of protein metabolic processGO:00512471780.016
Human
inorganic cation transmembrane transportGO:00986622020.016
regulation of molecular functionGO:00650093980.015
Human Mouse
positive regulation of cell communicationGO:00106472710.015
developmental process involved in reproductionGO:00030061590.015
cellular component movementGO:00069282480.015
anion transportGO:00068201780.015
multicellular organism reproductionGO:00325042330.015
proteolysisGO:00065081750.015
localization of cellGO:00516742020.015
transcription dna templatedGO:00063513770.015
negative regulation of signalingGO:00230571570.015
signal releaseGO:00230611450.015
response to nutrientGO:00075842480.015
regulation of membrane potentialGO:00423911100.015
positive regulation of cellular amine metabolic processGO:003324030.015
cell morphogenesisGO:00009021420.015
macromolecular complex subunit organizationGO:00439333390.015
positive regulation of cell differentiationGO:00455972170.015
ribonucleoside metabolic processGO:00091191740.015
Human Mouse
cell morphogenesis involved in differentiationGO:00009041190.015
regulation of cellular localizationGO:00603412630.015
positive regulation of cellular protein metabolic processGO:00322701670.014
Human
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
purine ribonucleotide metabolic processGO:00091502270.014
Human Mouse
fatty acid metabolic processGO:0006631990.014
cellular response to organic cyclic compoundGO:00714072020.014
regulation of cell proliferationGO:00421273590.014
cellular response to hormone stimulusGO:00328702470.014
nucleoside phosphate metabolic processGO:00067532830.014
Human Mouse
ras protein signal transductionGO:0007265290.014
cation transmembrane transportGO:00986552630.014
positive regulation of neurogenesisGO:00507691650.014
positive regulation of cell developmentGO:00107201760.014
positive regulation of protein modification processGO:00314011420.014
Human
intracellular transportGO:00469071850.014
Mouse
regulation of cellular ketone metabolic processGO:0010565270.014
monocarboxylic acid biosynthetic processGO:0072330480.014
response to carbohydrateGO:00097431830.014
anterior posterior pattern specificationGO:000995210.014
organic acid transportGO:00158491160.014
regulation of secretion by cellGO:19035302080.014
inorganic ion transmembrane transportGO:00986602290.014
cell part morphogenesisGO:00329901230.014
regulation of protein metabolic processGO:00512462890.014
Human
agingGO:00075682410.014
positive regulation of response to stimulusGO:00485842850.013
regulation of protein modification processGO:00313991940.013
Human
organic hydroxy compound metabolic processGO:19016151150.013
response to hexoseGO:00097461440.013
salivary gland developmentGO:000743130.013
response to monosaccharideGO:00342841590.013
regulation of anatomical structure sizeGO:00900661350.013
Human
regulation of catalytic activityGO:00507903040.013
Human Mouse
regulation of proteasomal protein catabolic processGO:006113640.013
sex differentiationGO:00075481130.013
metal ion homeostasisGO:00550651860.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
alpha amino acid metabolic processGO:1901605710.013
protein complex subunit organizationGO:00718223020.013
monocarboxylic acid metabolic processGO:00327871520.013
cellular response to lipidGO:00713962010.013
response to estrogenGO:00436272320.013
cellular ion homeostasisGO:00068731840.013
response to decreased oxygen levelsGO:00362932370.013
circulatory system developmentGO:00723591340.013
gastrulationGO:000736920.013
cell projection morphogenesisGO:00488581230.013
ribonucleoside catabolic processGO:00424541260.013
Human Mouse
negative regulation of cellular metabolic processGO:00313242810.013
glycosyl compound metabolic processGO:19016571820.013
Human Mouse
divalent inorganic cation homeostasisGO:00725071650.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
negative regulation of multicellular organismal processGO:00512412030.012
positive regulation of neuron projection developmentGO:0010976990.012
purine containing compound catabolic processGO:00725231380.012
Human Mouse
cellular response to organonitrogen compoundGO:00714171970.012
eye morphogenesisGO:004859240.012
axis specificationGO:000979840.012
regulation of synaptic transmissionGO:00508041410.012
reproductive structure developmentGO:00486081280.012
heart morphogenesisGO:000300730.012
regulation of cellular catabolic processGO:00313291010.012
Human Mouse
organophosphate biosynthetic processGO:00904071430.012
chromosome segregationGO:000705920.012
response to woundingGO:00096112540.012
peptide transportGO:0015833970.012
positive regulation of rna metabolic processGO:00512542030.012
response to transition metal nanoparticleGO:19902671220.012
positive regulation of nervous system developmentGO:00519621780.012
tissue developmentGO:00098882520.012
sensory perceptionGO:00076001010.012
regulation of homeostatic processGO:00328441010.012
morphogenesis of embryonic epitheliumGO:001633130.012
monovalent inorganic cation transportGO:00156721720.012
purine nucleoside metabolic processGO:00422781690.012
Human Mouse
protein complex assemblyGO:00064612630.012
developmental growthGO:00485891000.012
positive regulation of programmed cell deathGO:00430681570.012
regulation of catabolic processGO:00098941130.012
Human Mouse
gland developmentGO:00487321550.012
cellular cation homeostasisGO:00300031800.011
neuron projection morphogenesisGO:00488121220.011
regulation of anatomical structure morphogenesisGO:00226031410.011
cation homeostasisGO:00550801950.011
hormone secretionGO:00468791150.011
regulation of nucleotide metabolic processGO:00061401170.011
Human Mouse
positive regulation of secretion by cellGO:19035321280.011
gamete generationGO:00072761240.011
dephosphorylationGO:0016311980.011
macromolecular complex assemblyGO:00650032730.011
cellular response to nitrogen compoundGO:19016992100.011
cell motilityGO:00488702020.011
protein oligomerizationGO:00512591910.011
response to alkaloidGO:00432791320.011
response to insulinGO:00328681330.011
salivary gland morphogenesisGO:000743510.011
positive regulation of phosphorylationGO:00423271770.011
Human
cellular metal ion homeostasisGO:00068751720.011
protein complex biogenesisGO:00702712630.011
nucleoside phosphate catabolic processGO:19012921400.011
Human Mouse
purine nucleotide metabolic processGO:00061632290.011
Human Mouse
response to radiationGO:00093141370.011
positive regulation of neuron differentiationGO:00456661260.011
regulation of ion transportGO:00432692450.011
synaptic growth at neuromuscular junctionGO:005112410.011
single organism intracellular transportGO:19025821660.011
Mouse
gonad developmentGO:00084061040.011
forebrain developmentGO:0030900980.011
axonogenesisGO:0007409710.011
synaptic transmissionGO:00072682350.011
Mouse
cell migrationGO:00164771970.011
protein localizationGO:00081041910.011
Mouse
axon developmentGO:0061564960.011
regulation of cellular protein metabolic processGO:00322682670.011
Human
negative regulation of developmental processGO:00510931250.010
cellular component morphogenesisGO:00329891550.010
cellular calcium ion homeostasisGO:00068741600.010
sexual reproductionGO:00199531480.010
adult locomotory behaviorGO:000834440.010
positive regulation of rna biosynthetic processGO:19026801970.010
response to vitaminGO:00332731310.010
phosphatidylinositol dephosphorylationGO:004685640.010
regulation of organelle organizationGO:0033043800.010
regulation of blood circulationGO:19035221100.010
purine nucleotide catabolic processGO:00061951360.010
Human Mouse
cytoskeleton organizationGO:00070101110.010
organic acid catabolic processGO:0016054490.010
cellular protein localizationGO:00346131220.010
positive regulation of cell projection organizationGO:00313461110.010
positive regulation of protein phosphorylationGO:00019341350.010
Human
positive regulation of apoptotic processGO:00430651540.010

Als2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
Human
disease of anatomical entityDOID:700.024
Human
disease of cellular proliferationDOID:1456600.018
sensory system diseaseDOID:005015500.014
cancerDOID:16200.013
disease of metabolismDOID:001466700.010
central nervous system diseaseDOID:33100.010
Human