Rattus norvegicus

61 known processes

Cbs

cystathionine beta synthase

Cbs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.859
carboxylic acid metabolic processGO:00197522890.792
oxoacid metabolic processGO:00434362900.765
carboxylic acid biosynthetic processGO:0046394830.544
Yeast Mouse
cellular response to lipidGO:00713962010.504
alpha amino acid metabolic processGO:1901605710.485
fatty acid metabolic processGO:0006631990.438
macromolecule localizationGO:00330362520.364
cellular amino acid metabolic processGO:00065201070.344
monocarboxylic acid metabolic processGO:00327871520.314
single organism biosynthetic processGO:00447113420.293
Yeast Mouse
cation transportGO:00068123820.285
urogenital system developmentGO:0001655780.274
lipid metabolic processGO:00066292830.266
cellular response to endogenous stimulusGO:00714953770.258
response to campGO:0051591910.241
aromatic amino acid family metabolic processGO:000907290.233
regulation of multicellular organismal developmentGO:20000263760.233
response to acid chemicalGO:00011012220.211
Mouse
choline transportGO:001587140.192
small molecule biosynthetic processGO:00442831240.186
Yeast Mouse
carboxylic acid transportGO:00469421150.182
anion transportGO:00068201780.178
catabolic processGO:00090563510.174
cation transmembrane transportGO:00986552630.170
cellular response to hormone stimulusGO:00328702470.170
organic acid transportGO:00158491160.161
organic hydroxy compound metabolic processGO:19016151150.157
organic substance catabolic processGO:19015753160.157
organic anion transportGO:00157111320.154
alpha amino acid biosynthetic processGO:1901607230.153
Yeast Mouse
behaviorGO:00076102050.151
cellular modified amino acid metabolic processGO:0006575610.149
response to metal ionGO:00100382530.149
cellular response to organic cyclic compoundGO:00714072020.144
alpha amino acid catabolic processGO:1901606200.141
organic acid biosynthetic processGO:0016053830.140
Yeast Mouse
anion transmembrane transportGO:0098656770.134
sulfur compound metabolic processGO:0006790700.132
monocarboxylic acid transportGO:0015718520.123
ion transmembrane transportGO:00342203650.121
cellular amino acid catabolic processGO:0009063210.118
cellular response to organonitrogen compoundGO:00714171970.118
cellular homeostasisGO:00197252520.115
response to glucocorticoidGO:00513842230.115
cellular chemical homeostasisGO:00550822470.111
cellular response to oxygen containing compoundGO:19017013860.109
lipid biosynthetic processGO:00086101280.106
cell motilityGO:00488702020.104
renal system developmentGO:0072001670.104
response to extracellular stimulusGO:00099913800.101
single organism behaviorGO:00447081300.101
homeostatic processGO:00425923310.099
response to transition metal nanoparticleGO:19902671220.097
cellular amide metabolic processGO:0043603440.095
amine metabolic processGO:0009308380.093
lipid localizationGO:0010876620.092
aromatic amino acid family catabolic processGO:000907470.091
glutathione transportGO:003463520.089
locomotionGO:00400112370.088
carboxylic acid catabolic processGO:0046395490.088
small molecule catabolic processGO:0044282590.088
response to nutrient levelsGO:00316673700.087
cellular catabolic processGO:00442482950.087
organic acid catabolic processGO:0016054490.087
aromatic compound catabolic processGO:00194391680.085
carnitine transportGO:001587910.085
response to ketoneGO:19016541820.085
neurological system processGO:00508772190.084
learning or memoryGO:0007611900.082
cellular lipid metabolic processGO:00442552080.082
cellular amine metabolic processGO:0044106380.079
response to woundingGO:00096112540.079
transmembrane transportGO:00550854120.074
cellular ketone metabolic processGO:0042180510.074
macromolecular complex subunit organizationGO:00439333390.072
cognitionGO:0050890920.071
cellular response to nitrogen compoundGO:19016992100.070
cellular amino acid biosynthetic processGO:0008652320.070
Yeast Mouse
response to cytokineGO:00340972150.070
amino acid transmembrane transportGO:0003333330.070
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.069
regulation of rna metabolic processGO:00512523910.069
nucleobase containing small molecule metabolic processGO:00550863160.068
Mouse
positive regulation of extracellular matrix constituent secretionGO:000333120.068
acid secretionGO:0046717480.068
protein oligomerizationGO:00512591910.067
lipid transportGO:0006869610.067
intracellular signal transductionGO:00355563140.067
Mouse
antibiotic transportGO:004289120.066
fatty acid transportGO:0015908250.065
positive regulation of nucleobase containing compound metabolic processGO:00459353190.065
regulation of nucleic acid templated transcriptionGO:19035063800.065
single organism catabolic processGO:00447122830.064
positive regulation of nitrogen compound metabolic processGO:00511733340.063
regulation of locomotionGO:00400121480.063
regulation of rna biosynthetic processGO:20011413810.062
sulfur compound transportGO:007234880.062
rna metabolic processGO:00160704060.061
rhythmic processGO:00485111560.060
amino acid transportGO:0006865700.059
regulation of neural precursor cell proliferationGO:2000177160.059
secretionGO:00469033070.057
tripeptide transportGO:004293920.057
organonitrogen compound catabolic processGO:19015651790.057
nitrogen compound transportGO:00717052290.056
regulation of cellular protein metabolic processGO:00322682670.056
Mouse
protein localizationGO:00081041910.056
carbohydrate derivative metabolic processGO:19011353460.056
Mouse
response to inorganic substanceGO:00100353770.055
regulation of cellular ketone metabolic processGO:0010565270.055
response to biotic stimulusGO:00096072260.055
cellular component assemblyGO:00226073600.052
positive regulation of phosphate metabolic processGO:00459372620.052
cellular response to alcoholGO:0097306870.051
response to peptide hormoneGO:00434342780.051
reproductionGO:00000032450.051
Mouse
regulation of cellular component organizationGO:00511283680.050
agingGO:00075682410.050
regulation of cell migrationGO:00303341280.050
regulation of cell differentiationGO:00455953200.049
rna biosynthetic processGO:00327743800.048
long chain fatty acid metabolic processGO:0001676320.047
central nervous system developmentGO:00074173110.046
Mouse
chemical homeostasisGO:00488782920.046
regulation of phosphate metabolic processGO:00192203490.046
Mouse
regulation of phosphorylationGO:00423252480.045
Mouse
response to estradiolGO:00323551640.045
response to carbohydrateGO:00097431830.045
regulation of neurogenesisGO:00507672470.044
behavioral response to nicotineGO:003509520.044
divalent inorganic cation transportGO:00725111340.044
regulation of nervous system developmentGO:00519602640.043
regulation of molecular functionGO:00650093980.043
Mouse
gland developmentGO:00487321550.043
monoamine transportGO:0015844430.043
regulation of kinase activityGO:00435491170.043
Mouse
response to ethanolGO:00454711620.043
macromolecular complex assemblyGO:00650032730.043
kidney developmentGO:0001822670.043
response to corticosteroidGO:00319602350.042
metal ion transportGO:00300012890.042
drug transmembrane transportGO:0006855130.042
positive regulation of phosphorus metabolic processGO:00105622620.042
isoprenoid metabolic processGO:0006720450.042
regulation of cell proliferationGO:00421273590.042
forebrain developmentGO:0030900980.041
protein complex biogenesisGO:00702712630.041
cellular component biogenesisGO:00440853680.041
nucleic acid templated transcriptionGO:00976593790.041
cellular component movementGO:00069282480.041
response to mineralocorticoidGO:0051385490.041
multicellular organismal reproductive processGO:00486092330.040
Mouse
regulation of cellular amine metabolic processGO:003323880.040
positive regulation of developmental processGO:00510942830.040
positive regulation of transcription dna templatedGO:00458931970.039
positive regulation of cellular amino acid metabolic processGO:004576410.039
cellular response to growth factor stimulusGO:00713631620.039
positive regulation of cell migrationGO:0030335960.039
response to amineGO:0014075460.039
regulation of ion transportGO:00432692450.039
protein complex assemblyGO:00064612630.038
organonitrogen compound biosynthetic processGO:19015661670.038
Yeast Mouse
regulation of cellular amino acid metabolic processGO:000652120.038
multicellular organism growthGO:003526410.038
single organism reproductive processGO:00447022970.038
Mouse
response to organophosphorusGO:00466831020.037
response to molecule of bacterial originGO:00022371940.037
alcohol metabolic processGO:0006066770.037
regulation of protein kinase activityGO:00458591050.037
Mouse
inorganic ion transmembrane transportGO:00986602290.036
cellular nitrogen compound catabolic processGO:00442701630.036
response to alkaloidGO:00432791320.036
benzene containing compound metabolic processGO:0042537220.035
regulation of transcription dna templatedGO:00063553740.035
multi organism reproductive processGO:00447032620.035
Mouse
response to mechanical stimulusGO:00096121340.035
positive regulation of nucleic acid templated transcriptionGO:19035081970.035
response to estrogenGO:00436272320.035
response to manganese ionGO:0010042130.034
regulation of extracellular matrix constituent secretionGO:000333020.034
positive regulation of cellular component movementGO:00512721020.034
organic cyclic compound catabolic processGO:19013611750.034
tube developmentGO:0035295890.034
cellular ion homeostasisGO:00068731840.033
oligopeptide transportGO:000685740.033
response to fatty acidGO:0070542650.033
coenzyme metabolic processGO:0006732860.033
neurotransmitter uptakeGO:000150430.032
indole containing compound metabolic processGO:0042430110.032
regulation of cell developmentGO:00602842630.032
regulation of neuron differentiationGO:00456642080.032
positive regulation of cell differentiationGO:00455972170.032
response to nutrientGO:00075842480.032
Mouse
response to toxic substanceGO:00096361330.031
protein phosphorylationGO:00064683450.031
Mouse
positive regulation of catalytic activityGO:00430851840.031
response to monosaccharideGO:00342841590.031
positive regulation of amine transportGO:0051954260.031
positive regulation of intracellular signal transductionGO:19025331380.031
response to foodGO:0032094270.031
positive regulation of rna biosynthetic processGO:19026801970.031
regulation of neuron projection developmentGO:00109751610.031
organophosphate metabolic processGO:00196373700.031
Mouse
response to growth factorGO:00708481890.030
cellular response to peptideGO:19016531330.030
positive regulation of signalingGO:00230562700.030
quaternary ammonium group transportGO:001569760.030
response to other organismGO:00517072200.030
sodium independent organic anion transportGO:004325220.030
positive regulation of nervous system developmentGO:00519621780.030
positive regulation of protein modification processGO:00314011420.030
amine catabolic processGO:000931090.030
g protein coupled receptor signaling pathwayGO:00071862420.030
cell migrationGO:00164771970.030
regulation of protein phosphorylationGO:00019321830.029
Mouse
peristalsisGO:003043220.029
ribonucleoside metabolic processGO:00091191740.029
cation homeostasisGO:00550801950.029
purine containing compound metabolic processGO:00725212530.029
Mouse
regulation of anion transportGO:0044070430.029
regulation of phosphorus metabolic processGO:00511743490.028
Mouse
immune system processGO:00023762040.027
extracellular matrix constituent secretionGO:007027840.027
cellular cation homeostasisGO:00300031800.027
positive regulation of cellular amine metabolic processGO:003324030.027
nucleoside phosphate metabolic processGO:00067532830.027
Mouse
activation of jak2 kinase activityGO:004297720.026
transcription dna templatedGO:00063513770.026
heterocycle catabolic processGO:00467001670.026
reproductive structure developmentGO:00486081280.026
negative regulation of cell differentiationGO:0045596990.025
blood circulationGO:00080151830.025
Mouse
modified amino acid transportGO:0072337120.025
negative regulation of developmental processGO:00510931250.025
purine nucleotide metabolic processGO:00061632290.025
Mouse
unsaturated fatty acid metabolic processGO:0033559390.025
positive regulation of rna metabolic processGO:00512542030.025
organic hydroxy compound biosynthetic processGO:1901617510.025
cellular response to glucocorticoid stimulusGO:0071385680.025
peptidyl amino acid modificationGO:00181931260.025
smooth muscle cell proliferationGO:0048659770.025
development of primary sexual characteristicsGO:00451371070.024
response to molecule of fungal originGO:000223830.024
nucleotide metabolic processGO:00091172790.024
Mouse
epithelium developmentGO:0060429960.024
regulation of hormone secretionGO:00468831060.023
regulation of cellular component movementGO:00512701500.023
sexual reproductionGO:00199531480.023
cellular protein localizationGO:00346131220.023
cellular response to stressGO:00335542690.023
positive regulation of secretionGO:00510471400.023
circadian rhythmGO:0007623880.023
regulation of cell motilityGO:20001451310.023
multicellular organism reproductionGO:00325042330.022
Mouse
mapk cascadeGO:00001651400.022
Mouse
positive regulation of transportGO:00510502450.022
steroid metabolic processGO:0008202730.022
positive regulation of protein phosphorylationGO:00019341350.022
female pregnancyGO:00075651220.022
Mouse
regulation of mapk cascadeGO:00434081160.022
Mouse
regulation of protein metabolic processGO:00512462890.022
Mouse
amine transportGO:0015837570.022
protein complex subunit organizationGO:00718223020.022
negative regulation of multicellular organismal processGO:00512412030.022
regulation of neuronal synaptic plasticityGO:0048168310.022
regulation of transferase activityGO:00513381230.022
Mouse
negative regulation of macromolecule metabolic processGO:00106052600.022
astrocyte developmentGO:001400240.022
calcium ion transportGO:00068161310.022
negative regulation of cell proliferationGO:00082851190.022
divalent metal ion transportGO:00708381320.021
cytoplasmic transportGO:00164821150.021
positive regulation of neurogenesisGO:00507691650.021
protein tetramerizationGO:0051262380.021
regulation of anatomical structure sizeGO:00900661350.021
Mouse
protein homooligomerizationGO:0051260910.021
neurotransmitter transportGO:0006836420.021
neuron differentiationGO:00301823680.021
inorganic cation transmembrane transportGO:00986622020.021
positive regulation of biosynthetic processGO:00098913190.021
reproductive processGO:00224143720.021
Mouse
positive regulation of phosphorylationGO:00423271770.021
fatty acid derivative metabolic processGO:1901568380.020
negative regulation of synaptic transmission dopaminergicGO:003222740.020
oxidation reduction processGO:00551143040.020
negative regulation of protein metabolic processGO:00512481140.020
organophosphate catabolic processGO:00464341480.020
cellular response to acid chemicalGO:0071229750.020
positive regulation of ion transportGO:0043270940.020
glucose homeostasisGO:0042593750.020
dopamine transportGO:0015872180.020
regulation of secretionGO:00510462240.020
monocarboxylic acid biosynthetic processGO:0072330480.020
response to methanolGO:003398610.020
positive regulation of gene expressionGO:00106282440.019
positive regulation of endothelial cell migrationGO:001059540.019
positive regulation of mapk cascadeGO:0043410920.019
cellular calcium ion homeostasisGO:00068741600.019
secretion by cellGO:00329402480.019
regulation of intracellular signal transductionGO:19025312180.019
Mouse
regulation of apoptotic processGO:00429813350.019
cellular response to peptide hormone stimulusGO:00713751200.019
regulation of protein modification processGO:00313991940.019
Mouse
defense responseGO:00069521940.019
cellular response to campGO:0071320260.019
response to hexoseGO:00097461440.019
response to calcium ionGO:0051592590.019
regulation of tube sizeGO:0035150890.019
Mouse
positive regulation of protein kinase activityGO:0045860730.019
single organism membrane organizationGO:0044802740.018
positive regulation of protein metabolic processGO:00512471780.018
negative regulation of signalingGO:00230571570.018
icosanoid metabolic processGO:0006690380.018
transcription from rna polymerase ii promoterGO:00063662520.018
positive regulation of multicellular organismal processGO:00512403870.018
developmental process involved in reproductionGO:00030061590.018
nitrogen cycle metabolic processGO:007194150.018
mesoderm developmentGO:000749820.018
glial cell differentiationGO:0010001650.018
response to activityGO:0014823730.018
circulatory system processGO:00030131830.018
Mouse
cellular response to steroid hormone stimulusGO:0071383930.018
l glutamate importGO:005193820.018
tryptophan catabolic processGO:000656950.018
protein targetingGO:0006605610.018
long chain fatty acid transportGO:0015909140.018
positive regulation of extracellular matrix organizationGO:190305540.017
indolalkylamine metabolic processGO:000658650.017
regulation of synaptic transmissionGO:00508041410.017
linoleic acid metabolic processGO:004365140.017
fatty acid biosynthetic processGO:0006633330.017
negative regulation of molecular functionGO:00440921330.017
diterpenoid metabolic processGO:0016101330.017
intracellular transportGO:00469071850.017
female gonad developmentGO:0008585530.017
localization of cellGO:00516742020.017
carbohydrate derivative catabolic processGO:19011361470.017
potassium ion transmembrane transportGO:0071805710.017
purine ribonucleotide metabolic processGO:00091502270.017
Mouse
gamete generationGO:00072761240.017
negative regulation of serine type endopeptidase activityGO:190000410.017
response to testosteroneGO:0033574550.016
neuron projection developmentGO:00311752730.016
memoryGO:0007613540.016
cholesterol homeostasisGO:004263230.016
positive regulation of cell deathGO:00109421840.016
protein localization to membraneGO:0072657360.016
hepaticobiliary system developmentGO:0061008900.016
regulation of system processGO:00440572080.016
sterol catabolic processGO:001612710.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
intracellular protein transportGO:0006886790.016
response to zinc ionGO:0010043390.016
lipid catabolic processGO:0016042460.016
dopamine metabolic processGO:0042417120.016
regulation of programmed cell deathGO:00430673410.016
growthGO:00400071650.016
spermatogenesisGO:0007283990.016
muscle system processGO:00030121150.016
positive regulation of neuron differentiationGO:00456661260.016
response to decreased oxygen levelsGO:00362932370.015
renin angiotensin regulation of aldosterone productionGO:000201830.015
response to corticosteroneGO:0051412400.015
membrane organizationGO:0061024940.015
dicarboxylic acid metabolic processGO:0043648420.015
positive regulation of cellular component organizationGO:00511302000.015
nucleoside phosphate catabolic processGO:19012921400.015
response to vitaminGO:00332731310.015
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
cerebral cortex developmentGO:0021987180.015
metal ion homeostasisGO:00550651860.015
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.015
regulation of neurotransmitter levelsGO:0001505420.015
fluorene metabolic processGO:001891710.015
glycerolipid metabolic processGO:0046486670.015
purine nucleoside metabolic processGO:00422781690.015
terpenoid metabolic processGO:0006721370.015
small gtpase mediated signal transductionGO:0007264360.015
nucleocytoplasmic transportGO:0006913480.015
neuron developmentGO:00486662860.015
endocytosisGO:0006897840.015
action potentialGO:0001508540.015
pyridine containing compound metabolic processGO:0072524320.015
peptidyl tyrosine modificationGO:0018212720.015
synaptic transmissionGO:00072682350.015
acetate ester transportGO:190137470.015
gtp catabolic processGO:0006184710.015
response to osmotic stressGO:0006970420.014
positive regulation of cellular protein metabolic processGO:00322701670.014
gliogenesisGO:0042063930.014
response to bacteriumGO:00096172000.014
ras protein signal transductionGO:0007265290.014
response to lead ionGO:0010288330.014
regulation of metal ion transportGO:00109591180.014
response to radiationGO:00093141370.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
regulation of cell growthGO:0001558850.014
cellular response to hexose stimulusGO:0071331650.014
regulation of signal transductionGO:00099663180.014
Mouse
negative regulation of neuron differentiationGO:0045665620.014
positive regulation of homeostatic processGO:0032846490.014
glutamate receptor signaling pathwayGO:0007215430.014
negative regulation of cellular biosynthetic processGO:00313271610.014
cellular potassium ion transportGO:0071804720.014
halogenated hydrocarbon metabolic processGO:004219740.014
regulation of hormone levelsGO:00108171870.014
toxin transportGO:190199830.014
phospholipid metabolic processGO:0006644610.014
neuron deathGO:00709971270.014
circadian regulation of gene expressionGO:003292230.014
regulation of transcription regulatory region dna bindingGO:200067740.014
negative regulation of apoptotic processGO:00430661810.014
response to vitamin b6GO:003451610.014
response to vitamin dGO:0033280340.014
cell cell signalingGO:00072673350.014
response to glucoseGO:00097491360.014
positive regulation of nucleotide metabolic processGO:0045981910.014
naphthalene metabolic processGO:001893120.013
sterol homeostasisGO:005509230.013
regulation of stem cell differentiationGO:200073620.013
programmed cell deathGO:00125013920.013
cell projection organizationGO:00300303020.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
lipid storageGO:001991510.013
response to temperature stimulusGO:0009266940.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
lauric acid metabolic processGO:004825240.013
gastrulationGO:000736920.013
carbohydrate metabolic processGO:00059751300.013
positive regulation of kinase activityGO:0033674770.013
calcium ion homeostasisGO:00550741620.013
response to amino acidGO:0043200750.013
Mouse
reactive oxygen species biosynthetic processGO:190340980.013
single organism intracellular transportGO:19025821660.013
epithelial cell differentiationGO:0030855710.013
nucleoside metabolic processGO:00091161790.013
regulation of amino acid transportGO:0051955250.013
regulation of calcium ion transportGO:0051924770.013
positive regulation of programmed cell deathGO:00430681570.013
organophosphate biosynthetic processGO:00904071430.013
hormone transportGO:00099141210.013
negative regulation of collagen biosynthetic processGO:003296640.013
response to blue lightGO:000963710.013
regulation of cellular localizationGO:00603412630.013
regulation of activation of jak2 kinase activityGO:001053410.013
carbohydrate homeostasisGO:0033500750.013
cell growthGO:00160491040.013
positive regulation of molecular functionGO:00440932300.013
synaptic transmission dopaminergicGO:0001963110.013
calcium ion transmembrane transportGO:0070588700.013
response to light stimulusGO:0009416520.013
angiotensin mediated drinking behaviorGO:000305120.013
regulation of nucleotide metabolic processGO:00061401170.012
Mouse
response to oxygen levelsGO:00704822650.012
cellular response to external stimulusGO:00714961180.012
cellular metal ion homeostasisGO:00068751720.012
cofactor metabolic processGO:0051186950.012
positive regulation of neuron projection developmentGO:0010976990.012
negative regulation of cell communicationGO:00106481580.012
positive regulation of cell proliferationGO:00082842490.012
regenerationGO:00310991630.012
hemopoiesisGO:0030097340.012
peptidyl tyrosine phosphorylationGO:0018108720.012
male gamete generationGO:0048232990.012
cellular response to corticosteroid stimulusGO:0071384690.012
acylglycerol metabolic processGO:0006639210.012
ribose phosphate metabolic processGO:00196932350.012
Mouse
hexose metabolic processGO:0019318580.012
cellular response to gonadotropin stimulusGO:0071371170.012
regulation of synaptic plasticityGO:0048167700.012
renal sodium excretionGO:0035812200.012
protein transportGO:00150311320.012
hormone metabolic processGO:0042445690.012
positive regulation of response to stimulusGO:00485842850.012
cellular response to insulin stimulusGO:0032869810.012
positive regulation of cellular biosynthetic processGO:00313282950.012
head developmentGO:00603222470.012
Mouse
response to nicotineGO:0035094510.012
thioester metabolic processGO:0035383280.012
negative regulation of programmed cell deathGO:00430691830.012
vitamin a metabolic processGO:000677620.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
reproductive system developmentGO:00614581280.011
negative regulation of cellular metabolic processGO:00313242810.011
cellular response to fluid shear stressGO:007149840.011
proteolysisGO:00065081750.011

Cbs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.052
central nervous system diseaseDOID:33100.049
brain diseaseDOID:93600.049
inherited metabolic disorderDOID:65500.025
disease of metabolismDOID:001466700.025
vascular diseaseDOID:17800.017
cardiovascular system diseaseDOID:128700.017
essential hypertensionDOID:1082500.012
hypertensionDOID:1076300.012
artery diseaseDOID:005082800.012