Rattus norvegicus

25 known processes

Notch4

Notch homolog 4 (Drosophila)

Notch4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hormone transportGO:00099141210.254
ion transmembrane transportGO:00342203650.253
regulation of hormone levelsGO:00108171870.239
nitrogen compound transportGO:00717052290.236
positive regulation of signalingGO:00230562700.203
regulation of rna biosynthetic processGO:20011413810.181
peptide secretionGO:0002790860.174
positive regulation of signal transductionGO:00099671750.159
transmembrane transportGO:00550854120.159
signal releaseGO:00230611450.153
peptide transportGO:0015833970.146
regulation of secretion by cellGO:19035302080.142
regulation of peptide secretionGO:0002791820.135
anatomical structure morphogenesisGO:00096532980.133
positive regulation of cell communicationGO:00106472710.130
secretionGO:00469033070.118
secretion by cellGO:00329402480.113
regulation of transcription from rna polymerase ii promoterGO:00063572340.111
amide transportGO:00428861050.106
regulation of molecular functionGO:00650093980.103
transcription dna templatedGO:00063513770.101
inorganic ion transmembrane transportGO:00986602290.100
organic anion transportGO:00157111320.091
positive regulation of response to stimulusGO:00485842850.090
regulation of peptide hormone secretionGO:0090276800.089
hormone secretionGO:00468791150.087
negative regulation of cellular metabolic processGO:00313242810.087
actin filament based processGO:0030029860.084
reproductive processGO:00224143720.083
anion transportGO:00068201780.083
protein phosphorylationGO:00064683450.081
peptide hormone secretionGO:0030072840.080
multi organism reproductive processGO:00447032620.080
negative regulation of signalingGO:00230571570.079
regulation of cellular component organizationGO:00511283680.079
monocarboxylic acid transportGO:0015718520.079
carboxylic acid transportGO:00469421150.078
response to extracellular stimulusGO:00099913800.076
regulation of hormone secretionGO:00468831060.073
positive regulation of secretionGO:00510471400.072
neuronal stem cell maintenanceGO:009715020.070
carboxylic acid metabolic processGO:00197522890.070
peptidyl tyrosine phosphorylationGO:0018108720.067
cell motilityGO:00488702020.064
developmental process involved in reproductionGO:00030061590.062
localization of cellGO:00516742020.061
regulation of transferase activityGO:00513381230.059
regulation of peptide transportGO:0090087870.058
response to peptide hormoneGO:00434342780.058
lipid metabolic processGO:00066292830.057
neuron differentiationGO:00301823680.057
regulation of nucleic acid templated transcriptionGO:19035063800.056
negative regulation of secretion by cellGO:1903531720.056
lipid transportGO:0006869610.054
immune system processGO:00023762040.054
inorganic cation transmembrane transportGO:00986622020.054
multicellular organismal reproductive processGO:00486092330.054
single organism reproductive processGO:00447022970.053
organic acid transportGO:00158491160.053
cell cell signalingGO:00072673350.053
negative regulation of transportGO:00510511360.053
regulation of protein metabolic processGO:00512462890.053
macromolecular complex subunit organizationGO:00439333390.052
positive regulation of phosphate metabolic processGO:00459372620.050
negative regulation of programmed cell deathGO:00430691830.049
multicellular organism reproductionGO:00325042330.049
nucleic acid templated transcriptionGO:00976593790.048
organophosphate biosynthetic processGO:00904071430.047
locomotionGO:00400112370.047
reproductionGO:00000032450.047
rna biosynthetic processGO:00327743800.047
exocytosisGO:0006887600.046
cellular component biogenesisGO:00440853680.046
cellular response to peptide hormone stimulusGO:00713751200.046
neurotransmitter transportGO:0006836420.046
response to nutrient levelsGO:00316673700.046
rna metabolic processGO:00160704060.045
insulin secretionGO:0030073690.045
cellular component movementGO:00069282480.045
regulation of secretionGO:00510462240.044
regulation of response to stressGO:00801341260.044
regulation of rna metabolic processGO:00512523910.043
response to ammonium ionGO:0060359710.043
sexual reproductionGO:00199531480.042
organophosphate metabolic processGO:00196373700.042
lipid localizationGO:0010876620.042
regulation of catalytic activityGO:00507903040.041
organic acid metabolic processGO:00060822920.041
nucleoside phosphate metabolic processGO:00067532830.041
regulation of cell differentiationGO:00455953200.041
regulation of transcription dna templatedGO:00063553740.040
positive regulation of gene expressionGO:00106282440.040
monocarboxylic acid metabolic processGO:00327871520.039
protein autophosphorylationGO:0046777660.039
intracellular signal transductionGO:00355563140.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.039
cellular metal ion homeostasisGO:00068751720.039
amine metabolic processGO:0009308380.039
cell migrationGO:00164771970.038
regulation of activation of jak2 kinase activityGO:001053410.038
lymphoid progenitor cell differentiationGO:000232020.038
neurological system processGO:00508772190.038
negative regulation of macromolecule metabolic processGO:00106052600.037
positive regulation of cell migrationGO:0030335960.037
negative regulation of metabolic processGO:00098923310.037
cation transportGO:00068123820.037
positive regulation of rna metabolic processGO:00512542030.037
positive regulation of protein kinase activityGO:0045860730.036
cellular response to hormone stimulusGO:00328702470.036
positive regulation of developmental processGO:00510942830.036
regulation of cellular localizationGO:00603412630.036
carbohydrate metabolic processGO:00059751300.035
regulation of system processGO:00440572080.035
inflammatory responseGO:00069541500.034
pro t cell differentiationGO:000257210.034
gastrulationGO:000736920.034
regulation of cell projection organizationGO:00313441750.034
cellular calcium ion homeostasisGO:00068741600.033
regulation of kinase activityGO:00435491170.033
regulation of membrane potentialGO:00423911100.033
cellular carbohydrate metabolic processGO:0044262720.033
protein oligomerizationGO:00512591910.033
positive regulation of cell differentiationGO:00455972170.033
negative regulation of secretionGO:0051048820.033
acid secretionGO:0046717480.032
metal ion transportGO:00300012890.032
single organism carbohydrate metabolic processGO:00447231180.032
cellular response to organonitrogen compoundGO:00714171970.032
regulation of cellular protein metabolic processGO:00322682670.032
positive regulation of hormone secretionGO:0046887650.031
gliogenesisGO:0042063930.031
cyclic nucleotide biosynthetic processGO:0009190630.031
oxoacid metabolic processGO:00434362900.031
activation of jak2 kinase activityGO:004297720.031
positive regulation of secretion by cellGO:19035321280.031
regulation of phosphorus metabolic processGO:00511743490.031
peptidyl amino acid modificationGO:00181931260.030
positive regulation of phosphorus metabolic processGO:00105622620.030
bmp signaling pathwayGO:003050940.030
regulation of insulin secretionGO:0050796650.030
positive regulation of fatty acid transportGO:200019390.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
regulation of synaptic transmissionGO:00508041410.030
positive regulation of rna biosynthetic processGO:19026801970.030
growthGO:00400071650.030
immune responseGO:00069551040.030
regulation of protein phosphorylationGO:00019321830.030
carbohydrate biosynthetic processGO:0016051420.030
cellular response to organic cyclic compoundGO:00714072020.029
response to transition metal nanoparticleGO:19902671220.029
cation homeostasisGO:00550801950.029
macromolecule localizationGO:00330362520.029
regulation of phosphorylationGO:00423252480.029
positive regulation of cell motilityGO:2000147970.029
response to light stimulusGO:0009416520.029
positive regulation of protein metabolic processGO:00512471780.029
cellular component assemblyGO:00226073600.028
cellular amine metabolic processGO:0044106380.028
cytokine mediated signaling pathwayGO:0019221430.028
cell morphogenesis involved in differentiationGO:00009041190.028
regulation of programmed cell deathGO:00430673410.028
regulation of protein modification processGO:00313991940.027
negative regulation of follicle stimulating hormone secretionGO:004688230.027
negative regulation of apoptotic processGO:00430661810.027
phasic smooth muscle contractionGO:001482130.027
regulation of cellular amine metabolic processGO:003323880.027
g protein coupled receptor signaling pathwayGO:00071862420.026
negative regulation of cell communicationGO:00106481580.026
cellular lipid metabolic processGO:00442552080.026
agingGO:00075682410.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
negative regulation of biosynthetic processGO:00098901680.026
regulation of locomotionGO:00400121480.025
positive regulation of catalytic activityGO:00430851840.025
regulation of multicellular organismal developmentGO:20000263760.025
cellular response to endogenous stimulusGO:00714953770.025
response to peptideGO:19016522920.025
gamete generationGO:00072761240.025
sensory perceptionGO:00076001010.025
homeostatic processGO:00425923310.024
chemical homeostasisGO:00488782920.024
positive regulation of nitrogen compound metabolic processGO:00511733340.024
cell projection organizationGO:00300303020.024
cation transmembrane transportGO:00986552630.024
cellular divalent inorganic cation homeostasisGO:00725031620.024
regulation of response to external stimulusGO:00321011060.023
transcription from rna polymerase ii promoterGO:00063662520.023
neuron developmentGO:00486662860.023
single organism organelle organizationGO:19025891800.023
positive regulation of intracellular signal transductionGO:19025331380.023
regulation of phosphate metabolic processGO:00192203490.023
actin cytoskeleton organizationGO:0030036730.023
tissue developmentGO:00098882520.023
negative regulation of cell deathGO:00605482290.023
positive regulation of cellular biosynthetic processGO:00313282950.023
learningGO:0007612330.023
regulation of cellular amino acid metabolic processGO:000652120.023
sensory perception of painGO:0019233730.022
male gamete generationGO:0048232990.022
positive regulation of kinase activityGO:0033674770.022
regulation of signal transductionGO:00099663180.022
multicellular organism growthGO:003526410.022
detection of stimulusGO:0051606240.022
positive regulation of molecular functionGO:00440932300.021
positive regulation of mapk cascadeGO:0043410920.021
spermatogenesisGO:0007283990.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
positive regulation of peptide hormone secretionGO:0090277500.021
regulation of transmembrane transportGO:00347621220.021
response to mechanical stimulusGO:00096121340.021
single organism biosynthetic processGO:00447113420.021
biological adhesionGO:00226101100.021
calcium ion homeostasisGO:00550741620.021
regulation of cell migrationGO:00303341280.021
ion homeostasisGO:00508012120.020
reproductive structure developmentGO:00486081280.020
regulation of endothelial cell differentiationGO:004560140.020
regulation of apoptotic processGO:00429813350.020
positive regulation of cellular protein metabolic processGO:00322701670.020
monocarboxylic acid biosynthetic processGO:0072330480.020
cellular response to peptideGO:19016531330.019
programmed cell deathGO:00125013920.019
positive regulation of ion transportGO:0043270940.019
regulation of activation of janus kinase activityGO:001053310.019
digestive tract developmentGO:0048565390.019
endothelium developmentGO:0003158120.019
regulation of mapk cascadeGO:00434081160.019
cellular response to nitrogen compoundGO:19016992100.018
protein homooligomerizationGO:0051260910.018
regulation of nervous system developmentGO:00519602640.018
regulation of protein kinase activityGO:00458591050.018
response to external biotic stimulusGO:00432072210.018
response to nutrientGO:00075842480.018
apoptotic processGO:00069153810.018
mapk cascadeGO:00001651400.018
positive regulation of phosphorylationGO:00423271770.018
calcium ion transmembrane transportGO:0070588700.018
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.018
negative regulation of cellular component organizationGO:0051129830.018
regulation of immune system processGO:00026821230.018
neuron projection developmentGO:00311752730.018
regulation of cell activationGO:0050865500.018
negative regulation of neuron differentiationGO:0045665620.017
regulation of cell motilityGO:20001451310.017
regulation of neurogenesisGO:00507672470.017
t cell differentiationGO:003021790.017
mesoderm developmentGO:000749820.017
cellular ion homeostasisGO:00068731840.017
platelet derived growth factor receptor alpha signaling pathwayGO:003579010.017
regulation of ion transportGO:00432692450.017
detection of calcium ionGO:000551310.017
regulation of receptor activityGO:0010469290.017
regulation of cellular component biogenesisGO:0044087860.016
response to radiationGO:00093141370.016
membrane depolarizationGO:0051899320.016
leukocyte activationGO:0045321760.016
regulation of heart rateGO:0002027160.016
regulated secretory pathwayGO:0045055170.016
protein complex subunit organizationGO:00718223020.016
divalent inorganic cation transportGO:00725111340.016
cellular chemical homeostasisGO:00550822470.016
positive regulation of protein phosphorylationGO:00019341350.016
synaptic vesicle endocytosisGO:004848840.016
positive regulation of locomotionGO:00400171020.016
fatty acid transportGO:0015908250.016
negative regulation of innate immune responseGO:004582440.016
regulation of neuron differentiationGO:00456642080.016
carbohydrate derivative metabolic processGO:19011353460.016
regulation of cellular carbohydrate metabolic processGO:0010675390.016
response to metal ionGO:00100382530.015
positive regulation of biosynthetic processGO:00098913190.015
positive regulation of peptide secretionGO:0002793520.015
regulation of intracellular signal transductionGO:19025312180.015
response to molecule of fungal originGO:000223830.015
vesicle mediated transportGO:00161921810.015
protein complex assemblyGO:00064612630.015
positive regulation of serotonin secretionGO:001406410.015
regulation of cellular ketone metabolic processGO:0010565270.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
negative regulation of molecular functionGO:00440921330.015
purine nucleotide metabolic processGO:00061632290.015
adult locomotory behaviorGO:000834440.015
regulation of epithelial cell migrationGO:0010632170.015
nucleotide metabolic processGO:00091172790.015
cellular cation homeostasisGO:00300031800.014
ribose phosphate metabolic processGO:00196932350.014
ribonucleotide metabolic processGO:00092592310.014
regulation of ion transmembrane transportGO:00347651210.014
defense responseGO:00069521940.014
modified amino acid transportGO:0072337120.014
negative regulation of hormone secretionGO:0046888460.014
activation of protein kinase activityGO:0032147470.014
response to cgmpGO:007030530.014
taxisGO:0042330670.014
cytoskeleton organizationGO:00070101110.014
cellular response to growth factor stimulusGO:00713631620.014
positive regulation of neuron differentiationGO:00456661260.014
regulation of fatty acid transportGO:2000191100.014
metal ion homeostasisGO:00550651860.014
negative regulation of response to stimulusGO:00485851550.014
purine containing compound metabolic processGO:00725212530.014
negative regulation of amine transportGO:0051953240.014
positive regulation of cellular amine metabolic processGO:003324030.014
protein complex biogenesisGO:00702712630.014
neuron deathGO:00709971270.014
actin filament bundle organizationGO:0061572190.014
saliva secretionGO:004654130.014
positive regulation of receptor activityGO:200027340.014
acute inflammatory responseGO:0002526580.014
regulation of immunoglobulin secretionGO:005102310.014
negative regulation of luteinizing hormone secretionGO:003368540.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
olfactory behaviorGO:004204820.014
salivary gland developmentGO:000743130.014
alcohol metabolic processGO:0006066770.013
monovalent inorganic cation transportGO:00156721720.013
negative regulation of cell differentiationGO:0045596990.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
neuropeptide signaling pathwayGO:0007218290.013
cell activationGO:0001775970.013
regulation of nucleotide metabolic processGO:00061401170.013
negative regulation of multicellular organismal processGO:00512412030.013
regulation of organelle organizationGO:0033043800.013
positive regulation of map kinase activityGO:0043406460.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
positive regulation of transportGO:00510502450.013
peptidyl tyrosine modificationGO:0018212720.013
positive regulation of neurogenesisGO:00507691650.013
positive regulation of transferase activityGO:0051347810.013
negative regulation of cellular protein metabolic processGO:00322691060.013
regulation of camp biosynthetic processGO:0030817380.013
synaptic transmissionGO:00072682350.013
synaptic vesicle transportGO:0048489230.013
desensitization of g protein coupled receptor protein signaling pathwayGO:0002029100.013
response to muscle stretchGO:003599420.013
response to woundingGO:00096112540.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
positive regulation of immunoglobulin productionGO:000263940.012
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
synaptic vesicle localizationGO:0097479240.012
response to biotic stimulusGO:00096072260.012
prostaglandin secretionGO:003231060.012
gastric motilityGO:003548230.012
nucleoside phosphate catabolic processGO:19012921400.012
cell projection morphogenesisGO:00488581230.012
divalent metal ion transportGO:00708381320.012
organ regenerationGO:00311001010.012
neuron neuron synaptic transmissionGO:0007270600.012
negative regulation of vesicle fusionGO:003133920.012
ribonucleotide catabolic processGO:00092611360.012
positive regulation of multicellular organismal processGO:00512403870.012
macromolecular complex assemblyGO:00650032730.012
positive regulation of endothelial cell differentiationGO:004560320.012
regulation of immunoglobulin productionGO:000263740.012
response to growth factorGO:00708481890.012
lipid storageGO:001991510.011
motor neuron axon guidanceGO:000804510.011
cell junction organizationGO:0034330210.011
anion transmembrane transportGO:0098656770.011
ossificationGO:0001503700.011
cellular response to drugGO:0035690300.011
release of cytochrome c from mitochondriaGO:000183680.011
response to foodGO:0032094270.011
response to ethanolGO:00454711620.011
carbohydrate derivative biosynthetic processGO:19011371240.011
purine ribonucleotide metabolic processGO:00091502270.011
mesodermal cell differentiationGO:004833310.011
response to acid chemicalGO:00011012220.011
cellular catabolic processGO:00442482950.011
response to hexoseGO:00097461440.011
glial cell differentiationGO:0010001650.011
lymphocyte activation involved in immune responseGO:000228530.011
regulation of regulated secretory pathwayGO:190330570.011
female pregnancyGO:00075651220.011
immune effector processGO:0002252530.011
cellular homeostasisGO:00197252520.011
response to laminar fluid shear stressGO:003461690.011
single organism behaviorGO:00447081300.011
neuron projection morphogenesisGO:00488121220.011
organelle localizationGO:0051640550.011
regulation of dendrite developmentGO:0050773590.011
regulation of exocytosisGO:0017157370.011
cellular response to alkaloidGO:0071312250.011
response to amineGO:0014075460.011
positive regulation of insulin secretionGO:0032024360.011
positive regulation of cell developmentGO:00107201760.011
synaptic transmission glutamatergicGO:0035249330.011
morphogenesis of a polarized epitheliumGO:000173810.011
regulation of protein serine threonine kinase activityGO:0071900640.010
gastric inhibitory peptide signaling pathwayGO:003819210.010
entrainment of circadian clockGO:000964930.010
regulation of rho gtpase activityGO:0032319170.010
cellular response to oxygen containing compoundGO:19017013860.010
response to other organismGO:00517072200.010
response to estradiolGO:00323551640.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
positive regulation of cell projection organizationGO:00313461110.010
organic hydroxy compound metabolic processGO:19016151150.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
glucose metabolic processGO:0006006520.010
membrane organizationGO:0061024940.010
cell migration involved in kidney developmentGO:003578720.010
signal transduction by phosphorylationGO:00230141440.010
prostaglandin transportGO:001573280.010
cellular component morphogenesisGO:00329891550.010
positive regulation of protein modification processGO:00314011420.010
circulatory system processGO:00030131830.010

Notch4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.020
neuropathyDOID:87000.019
neuromuscular diseaseDOID:44000.019
gastrointestinal system diseaseDOID:7700.016
cardiovascular system diseaseDOID:128700.014
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012