Rattus norvegicus

187 known processes

Kdm1

lysine (K)-specific demethylase 1

(Aliases: Aof2,RGD1562975)

Kdm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleic acid templated transcriptionGO:00976593790.071
transcription dna templatedGO:00063513770.069
macromolecular complex subunit organizationGO:00439333390.050
regulation of nucleic acid templated transcriptionGO:19035063800.050
regulation of cellular component organizationGO:00511283680.050
regulation of protein metabolic processGO:00512462890.047
organic substance catabolic processGO:19015753160.047
regulation of rna biosynthetic processGO:20011413810.046
negative regulation of gene expressionGO:00106291990.045
Human
cellular catabolic processGO:00442482950.045
macromolecule localizationGO:00330362520.044
regulation of multicellular organismal developmentGO:20000263760.044
carboxylic acid metabolic processGO:00197522890.044
negative regulation of nitrogen compound metabolic processGO:00511721610.042
Human
regulation of rna metabolic processGO:00512523910.041
rna biosynthetic processGO:00327743800.040
transcription from rna polymerase ii promoterGO:00063662520.039
cellular response to stressGO:00335542690.039
Human
organic acid metabolic processGO:00060822920.039
rna metabolic processGO:00160704060.038
organelle organizationGO:00069962660.038
oxoacid metabolic processGO:00434362900.037
negative regulation of rna metabolic processGO:00512531230.037
Human
catabolic processGO:00090563510.036
chromosome segregationGO:000705920.035
positive regulation of nitrogen compound metabolic processGO:00511733340.034
ribonucleotide metabolic processGO:00092592310.034
negative regulation of macromolecule metabolic processGO:00106052600.034
Human
positive regulation of multicellular organismal processGO:00512403870.033
regulation of catalytic activityGO:00507903040.032
dna integrity checkpointGO:003157020.031
positive regulation of rna metabolic processGO:00512542030.031
organophosphate metabolic processGO:00196373700.031
central nervous system developmentGO:00074173110.030
negative regulation of metabolic processGO:00098923310.030
Human
regulation of transcription dna templatedGO:00063553740.030
negative regulation of cellular biosynthetic processGO:00313271610.029
Human
cellular ketone metabolic processGO:0042180510.028
positive regulation of biosynthetic processGO:00098913190.027
positive regulation of gene expressionGO:00106282440.027
positive regulation of cell differentiationGO:00455972170.027
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
cellular amine metabolic processGO:0044106380.026
homeostatic processGO:00425923310.026
regulation of apoptotic processGO:00429813350.026
Human
positive regulation of developmental processGO:00510942830.026
positive regulation of cellular biosynthetic processGO:00313282950.025
ion transmembrane transportGO:00342203650.025
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
Human
regulation of cellular protein metabolic processGO:00322682670.024
regulation of cellular ketone metabolic processGO:0010565270.024
protein complex subunit organizationGO:00718223020.023
regulation of cellular amine metabolic processGO:003323880.023
transmembrane transportGO:00550854120.023
positive regulation of neurogenesisGO:00507691650.022
neuron projection developmentGO:00311752730.022
positive regulation of cellular protein metabolic processGO:00322701670.022
proteolysisGO:00065081750.022
amine metabolic processGO:0009308380.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
Human
nucleobase containing small molecule metabolic processGO:00550863160.022
regulation of response to stressGO:00801341260.021
Human
regulation of cellular localizationGO:00603412630.021
regulation of programmed cell deathGO:00430673410.021
Human
cellular chemical homeostasisGO:00550822470.021
negative regulation of cellular metabolic processGO:00313242810.020
Human
negative regulation of apoptotic processGO:00430661810.020
Human
regulation of molecular functionGO:00650093980.020
nucleotide metabolic processGO:00091172790.019
single organism organelle organizationGO:19025891800.019
nucleoside phosphate metabolic processGO:00067532830.019
negative regulation of biosynthetic processGO:00098901680.019
Human
negative regulation of rna biosynthetic processGO:19026791180.019
Human
single organism reproductive processGO:00447022970.019
spindle organizationGO:000705120.019
apoptotic processGO:00069153810.019
Human
reproductive processGO:00224143720.019
response to growth factorGO:00708481890.019
regulation of cellular amino acid metabolic processGO:000652120.019
positive regulation of protein metabolic processGO:00512471780.019
neuron developmentGO:00486662860.018
nitrogen compound transportGO:00717052290.018
response to decreased oxygen levelsGO:00362932370.018
cellular amino acid metabolic processGO:00065201070.018
carbohydrate derivative metabolic processGO:19011353460.018
intracellular transportGO:00469071850.018
positive regulation of signalingGO:00230562700.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
protein modification by small protein conjugation or removalGO:0070647350.018
regulation of neurogenesisGO:00507672470.018
positive regulation of molecular functionGO:00440932300.018
positive regulation of response to stimulusGO:00485842850.018
reproductionGO:00000032450.018
cellular response to endogenous stimulusGO:00714953770.018
positive regulation of transcription dna templatedGO:00458931970.017
response to oxygen levelsGO:00704822650.017
cellular response to growth factor stimulusGO:00713631620.017
regulation of cellular catabolic processGO:00313291010.017
cation homeostasisGO:00550801950.017
negative regulation of cell communicationGO:00106481580.017
Human
glycosyl compound metabolic processGO:19016571820.017
ribonucleoside metabolic processGO:00091191740.017
chemical homeostasisGO:00488782920.017
negative regulation of programmed cell deathGO:00430691830.017
Human
oxidation reduction processGO:00551143040.017
Human
positive regulation of nervous system developmentGO:00519621780.017
cell projection organizationGO:00300303020.017
multicellular organism growthGO:003526410.017
single organism catabolic processGO:00447122830.017
cation transportGO:00068123820.016
embryonic pattern specificationGO:000988010.016
intracellular signal transductionGO:00355563140.016
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.016
Human
nucleoside metabolic processGO:00091161790.016
cell cycleGO:00070491010.016
regulation of cell differentiationGO:00455953200.016
purine ribonucleotide metabolic processGO:00091502270.016
nuclear transportGO:0051169490.016
anatomical structure morphogenesisGO:00096532980.016
ion homeostasisGO:00508012120.016
positive regulation of transportGO:00510502450.015
protein phosphorylationGO:00064683450.015
mitotic spindle organizationGO:000705220.015
regulation of phosphorus metabolic processGO:00511743490.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
Human
neurological system processGO:00508772190.015
purine nucleotide metabolic processGO:00061632290.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
cellular response to oxygen containing compoundGO:19017013860.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
Human
single organism intracellular transportGO:19025821660.015
single organism cellular localizationGO:19025801020.015
positive regulation of rna biosynthetic processGO:19026801970.015
multi organism reproductive processGO:00447032620.015
regulation of catabolic processGO:00098941130.015
cell motilityGO:00488702020.015
ribose phosphate metabolic processGO:00196932350.015
regulation of nervous system developmentGO:00519602640.015
positive regulation of cellular amine metabolic processGO:003324030.014
metal ion transportGO:00300012890.014
response to acid chemicalGO:00011012220.014
regulation of cell cycleGO:0051726730.014
reproductive structure developmentGO:00486081280.014
regulation of organelle organizationGO:0033043800.014
negative regulation of response to stimulusGO:00485851550.014
Human
cellular response to transforming growth factor beta stimulusGO:0071560410.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
head developmentGO:00603222470.014
multicellular organismal reproductive processGO:00486092330.014
neuron differentiationGO:00301823680.014
response to estrogenGO:00436272320.014
negative regulation of cell deathGO:00605482290.014
Human
cellular cation homeostasisGO:00300031800.014
cellular response to organic cyclic compoundGO:00714072020.014
regulation of mrna splicing via spliceosomeGO:004802430.014
gamete generationGO:00072761240.014
development of primary sexual characteristicsGO:00451371070.014
metal ion homeostasisGO:00550651860.014
nucleocytoplasmic transportGO:0006913480.014
regulation of neuron differentiationGO:00456642080.013
carbohydrate metabolic processGO:00059751300.013
lipid metabolic processGO:00066292830.013
nucleoside triphosphate metabolic processGO:00091411440.013
gastrulationGO:000736920.013
purine nucleoside metabolic processGO:00422781690.013
ribonucleotide biosynthetic processGO:0009260850.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
response to nutrient levelsGO:00316673700.013
response to woundingGO:00096112540.013
negative regulation of developmental processGO:00510931250.013
axis specificationGO:000979840.013
programmed cell deathGO:00125013920.013
Human
cell cycle checkpointGO:000007520.013
negative regulation of transcription dna templatedGO:00458921160.013
Human
anion transportGO:00068201780.013
organic acid transportGO:00158491160.013
ribose phosphate biosynthetic processGO:0046390870.013
gonad developmentGO:00084061040.013
response to extracellular stimulusGO:00099913800.013
protein complex assemblyGO:00064612630.012
regulation of hydrolase activityGO:00513361430.012
protein localizationGO:00081041910.012
protein targeting to nucleusGO:0044744350.012
tissue developmentGO:00098882520.012
cellular response to cytokine stimulusGO:00713451270.012
cellular component assemblyGO:00226073600.012
positive regulation of cell developmentGO:00107201760.012
organic anion transportGO:00157111320.012
adult locomotory behaviorGO:000834440.012
cellular component movementGO:00069282480.012
cell cycle processGO:0022402570.012
positive regulation of neuron differentiationGO:00456661260.012
reproductive system developmentGO:00614581280.012
sex differentiationGO:00075481130.012
dna metabolic processGO:0006259960.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
purine containing compound metabolic processGO:00725212530.012
locomotionGO:00400112370.012
negative regulation of cell cycle phase transitionGO:190198840.011
regulation of protein modification processGO:00313991940.011
carbohydrate derivative biosynthetic processGO:19011371240.011
macromolecular complex assemblyGO:00650032730.011
cellular macromolecule localizationGO:00707271220.011
response to inorganic substanceGO:00100353770.011
regulation of cell proliferationGO:00421273590.011
negative regulation of multicellular organismal processGO:00512412030.011
response to hypoxiaGO:00016662310.011
positive regulation of neuron projection developmentGO:0010976990.011
cellular ion homeostasisGO:00068731840.011
regulation of proteolysisGO:0030162660.011
protein transportGO:00150311320.011
regulation of cell developmentGO:00602842630.011
cellular homeostasisGO:00197252520.011
cation transmembrane transportGO:00986552630.011
regulation of cellular response to stressGO:0080135490.011
Human
purine ribonucleoside metabolic processGO:00461281680.011
positive regulation of signal transductionGO:00099671750.011
embryo developmentGO:0009790490.011
bmp signaling pathwayGO:003050940.011
nucleotide biosynthetic processGO:0009165980.011
protein localization to nucleusGO:0034504390.011
acid secretionGO:0046717480.011
negative regulation of cell proliferationGO:00082851190.011
mitotic sister chromatid segregationGO:000007010.011
regulation of intracellular signal transductionGO:19025312180.010
Human
macromolecule catabolic processGO:0009057580.010
protein oligomerizationGO:00512591910.010
positive regulation of cell projection organizationGO:00313461110.010
regulation of anatomical structure morphogenesisGO:00226031410.010
regulation of phosphorylationGO:00423252480.010
organophosphate biosynthetic processGO:00904071430.010
multicellular organism reproductionGO:00325042330.010
response to estradiolGO:00323551640.010
protein maturationGO:0051604680.010
protein processingGO:0016485680.010
immune system processGO:00023762040.010
regulation of neuron projection developmentGO:00109751610.010
positive regulation of cell communicationGO:00106472710.010
protein complex biogenesisGO:00702712630.010
sensory organ developmentGO:0007423740.010
cytoskeleton organizationGO:00070101110.010
regulation of cell projection organizationGO:00313441750.010
inorganic cation transmembrane transportGO:00986622020.010

Kdm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.013
central nervous system diseaseDOID:33100.011