Rattus norvegicus

7 known processes

Sphk2

sphingosine kinase 2

Sphk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.153
Rat
organophosphate metabolic processGO:00196373700.143
regulation of molecular functionGO:00650093980.138
cellular component biogenesisGO:00440853680.137
protein phosphorylationGO:00064683450.137
Rat
regulation of catalytic activityGO:00507903040.129
regulation of signal transductionGO:00099663180.125
cellular component assemblyGO:00226073600.117
regulation of phosphorus metabolic processGO:00511743490.111
Rat
head developmentGO:00603222470.104
intracellular signal transductionGO:00355563140.101
Yeast
macromolecule localizationGO:00330362520.100
regulation of nervous system developmentGO:00519602640.089
Rat
lipid metabolic processGO:00066292830.088
Yeast Rat Fly
regulation of intracellular signal transductionGO:19025312180.086
single organism biosynthetic processGO:00447113420.084
Rat
central nervous system developmentGO:00074173110.081
cellular lipid metabolic processGO:00442552080.080
Yeast Rat Fly
regulation of cellular component organizationGO:00511283680.080
Rat
protein complex assemblyGO:00064612630.079
nucleotide metabolic processGO:00091172790.079
cellular component movementGO:00069282480.077
Rat
locomotionGO:00400112370.071
Rat
single organism cellular localizationGO:19025801020.068
regulation of phosphorylationGO:00423252480.067
Rat
regulation of phosphate metabolic processGO:00192203490.067
Rat
negative regulation of metabolic processGO:00098923310.066
localization of cellGO:00516742020.065
Rat
carboxylic acid metabolic processGO:00197522890.064
Rat
purine containing compound metabolic processGO:00725212530.059
positive regulation of phosphate metabolic processGO:00459372620.058
Rat
positive regulation of cell communicationGO:00106472710.056
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.056
vesicle mediated transportGO:00161921810.054
regulation of cell differentiationGO:00455953200.054
Rat
neuron developmentGO:00486662860.053
Rat
nucleobase containing small molecule metabolic processGO:00550863160.051
nucleic acid templated transcriptionGO:00976593790.050
negative regulation of cellular metabolic processGO:00313242810.050
lipid biosynthetic processGO:00086101280.050
Rat
regulation of multicellular organismal developmentGO:20000263760.049
Rat
cell migrationGO:00164771970.048
Rat
purine ribonucleoside catabolic processGO:00461301240.048
cell motilityGO:00488702020.048
Rat
ribose phosphate metabolic processGO:00196932350.047
brain developmentGO:00074202470.047
oxoacid metabolic processGO:00434362900.047
Rat
response to inorganic substanceGO:00100353770.047
Rat
cellular amino acid metabolic processGO:00065201070.047
programmed cell deathGO:00125013920.046
Rat
regulation of cell developmentGO:00602842630.046
Rat
nucleoside triphosphate metabolic processGO:00091411440.046
nucleoside phosphate metabolic processGO:00067532830.046
carbohydrate derivative metabolic processGO:19011353460.045
single organism catabolic processGO:00447122830.045
organophosphate biosynthetic processGO:00904071430.044
nucleoside triphosphate catabolic processGO:00091431230.044
cell projection organizationGO:00300303020.044
Rat
regulation of neuron differentiationGO:00456642080.043
Rat
positive regulation of response to stimulusGO:00485842850.043
positive regulation of nucleobase containing compound metabolic processGO:00459353190.042
purine ribonucleotide catabolic processGO:00091541360.042
rna biosynthetic processGO:00327743800.042
ribonucleoside metabolic processGO:00091191740.041
regulation of locomotionGO:00400121480.041
Rat
purine nucleoside metabolic processGO:00422781690.041
regulation of transcription dna templatedGO:00063553740.040
purine ribonucleotide metabolic processGO:00091502270.040
organonitrogen compound catabolic processGO:19015651790.040
negative regulation of molecular functionGO:00440921330.039
small gtpase mediated signal transductionGO:0007264360.039
regulation of immune system processGO:00026821230.039
regulation of protein metabolic processGO:00512462890.038
Rat
nucleoside metabolic processGO:00091161790.038
secretionGO:00469033070.037
Rat
ribonucleotide catabolic processGO:00092611360.037
positive regulation of neurogenesisGO:00507691650.037
Rat
glycerolipid metabolic processGO:0046486670.037
single organism intracellular transportGO:19025821660.037
macromolecular complex assemblyGO:00650032730.037
macromolecular complex subunit organizationGO:00439333390.036
neuron differentiationGO:00301823680.036
Rat
purine ribonucleoside triphosphate catabolic processGO:00092071220.036
cell cell signalingGO:00072673350.036
Rat
purine ribonucleoside metabolic processGO:00461281680.035
immune system processGO:00023762040.035
glycosyl compound metabolic processGO:19016571820.035
reproductionGO:00000032450.035
Fly
regulation of protein phosphorylationGO:00019321830.035
Rat
ribonucleoside triphosphate metabolic processGO:00091991410.035
organophosphate catabolic processGO:00464341480.035
heterocycle catabolic processGO:00467001670.034
reproductive processGO:00224143720.033
cellular ketone metabolic processGO:0042180510.033
cellular amine metabolic processGO:0044106380.033
ribonucleotide metabolic processGO:00092592310.033
purine nucleoside catabolic processGO:00061521240.032
positive regulation of protein modification processGO:00314011420.032
Rat
nucleotide catabolic processGO:00091661390.032
cellular response to hormone stimulusGO:00328702470.032
purine ribonucleoside triphosphate metabolic processGO:00092051400.032
regulation of cellular localizationGO:00603412630.031
Rat
cellular catabolic processGO:00442482950.031
regulation of neurogenesisGO:00507672470.031
Rat
glycosyl compound catabolic processGO:19016581260.031
nucleoside phosphate catabolic processGO:19012921400.031
positive regulation of phosphorus metabolic processGO:00105622620.031
Rat
rna metabolic processGO:00160704060.031
ion transmembrane transportGO:00342203650.031
ribonucleoside catabolic processGO:00424541260.031
cell adhesionGO:00071551100.030
nucleoside catabolic processGO:00091641260.030
positive regulation of cell deathGO:00109421840.030
response to nutrient levelsGO:00316673700.030
Rat
regulation of cellular ketone metabolic processGO:0010565270.030
negative regulation of cell differentiationGO:0045596990.030
organic cyclic compound catabolic processGO:19013611750.030
ras protein signal transductionGO:0007265290.029
carbohydrate derivative catabolic processGO:19011361470.029
negative regulation of response to stimulusGO:00485851550.029
regulation of neuron projection developmentGO:00109751610.029
Rat
protein complex subunit organizationGO:00718223020.028
telencephalon developmentGO:0021537620.028
response to metal ionGO:00100382530.028
Rat
anterior posterior pattern specificationGO:000995210.028
positive regulation of catalytic activityGO:00430851840.028
regulation of cellular component movementGO:00512701500.027
Rat
regulation of protein modification processGO:00313991940.027
Rat
establishment of protein localizationGO:00451841410.027
cellular response to oxygen containing compoundGO:19017013860.027
Rat
single organism membrane organizationGO:0044802740.027
organic substance catabolic processGO:19015753160.027
organonitrogen compound biosynthetic processGO:19015661670.027
gland developmentGO:00487321550.027
regulation of cellular amino acid metabolic processGO:000652120.027
regulation of anatomical structure morphogenesisGO:00226031410.026
response to cytokineGO:00340972150.026
Rat
small molecule biosynthetic processGO:00442831240.026
Rat
intracellular transportGO:00469071850.026
regulation of rna metabolic processGO:00512523910.026
positive regulation of cellular component movementGO:00512721020.026
Rat
response to peptideGO:19016522920.026
positive regulation of cellular biosynthetic processGO:00313282950.025
protein localizationGO:00081041910.025
amine metabolic processGO:0009308380.025
inorganic cation transmembrane transportGO:00986622020.025
apoptotic processGO:00069153810.025
Rat
homeostatic processGO:00425923310.025
regulation of cellular amine metabolic processGO:003323880.025
anatomical structure morphogenesisGO:00096532980.025
cellular protein localizationGO:00346131220.025
regulation of cell proliferationGO:00421273590.025
negative regulation of multicellular organismal processGO:00512412030.025
membrane organizationGO:0061024940.025
positive regulation of cell developmentGO:00107201760.025
Rat
signal transduction by phosphorylationGO:00230141440.025
positive regulation of cellular component organizationGO:00511302000.024
Rat
positive regulation of intracellular signal transductionGO:19025331380.024
regulation of secretionGO:00510462240.024
Rat
oxidation reduction processGO:00551143040.024
cardiovascular system developmentGO:00723581340.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
aromatic compound catabolic processGO:00194391680.024
purine nucleotide metabolic processGO:00061632290.024
negative regulation of transportGO:00510511360.023
regulation of hydrolase activityGO:00513361430.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
negative regulation of neurogenesisGO:0050768780.023
phospholipid metabolic processGO:0006644610.023
regulation of transferase activityGO:00513381230.023
neuron projection developmentGO:00311752730.023
Rat
positive regulation of phosphorylationGO:00423271770.023
Rat
regulation of rna biosynthetic processGO:20011413810.023
organelle organizationGO:00069962660.023
positive regulation of molecular functionGO:00440932300.023
protein oligomerizationGO:00512591910.023
regulation of kinase activityGO:00435491170.022
negative regulation of cell communicationGO:00106481580.022
positive regulation of cellular amine metabolic processGO:003324030.022
nucleobase containing compound catabolic processGO:00346551520.022
positive regulation of cell migrationGO:0030335960.022
Rat
hematopoietic or lymphoid organ developmentGO:0048534360.022
response to carbohydrateGO:00097431830.021
regulation of cellular catabolic processGO:00313291010.021
regulation of mapk cascadeGO:00434081160.021
purine nucleotide catabolic processGO:00061951360.021
ribonucleoside triphosphate catabolic processGO:00092031220.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
positive regulation of cell proliferationGO:00082842490.021
protein transportGO:00150311320.021
guanosine containing compound metabolic processGO:1901068740.021
negative regulation of cell developmentGO:0010721820.021
anion transportGO:00068201780.021
protein complex biogenesisGO:00702712630.021
response to hexoseGO:00097461440.021
regulation of cellular protein metabolic processGO:00322682670.021
Rat
regulation of catabolic processGO:00098941130.020
regulation of cell motilityGO:20001451310.020
Rat
regulation of protein localizationGO:0032880810.020
neuron projection morphogenesisGO:00488121220.020
cellular component morphogenesisGO:00329891550.020
cellular macromolecule localizationGO:00707271220.020
positive regulation of biosynthetic processGO:00098913190.020
catabolic processGO:00090563510.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
cytoskeleton organizationGO:00070101110.020
intracellular protein transportGO:0006886790.020
response to growth factorGO:00708481890.019
Rat
positive regulation of transportGO:00510502450.019
Rat
leukocyte activationGO:0045321760.019
negative regulation of cell proliferationGO:00082851190.019
cellular response to endogenous stimulusGO:00714953770.019
endocytosisGO:0006897840.019
regulation of lipid metabolic processGO:0019216680.019
negative regulation of nitrogen compound metabolic processGO:00511721610.019
negative regulation of catalytic activityGO:00430861030.019
multi organism reproductive processGO:00447032620.019
response to external biotic stimulusGO:00432072210.019
dephosphorylationGO:0016311980.019
positive regulation of apoptotic processGO:00430651540.019
negative regulation of phosphate metabolic processGO:0045936800.019
forebrain developmentGO:0030900980.019
transcription dna templatedGO:00063513770.019
positive regulation of signalingGO:00230562700.019
Rat
negative regulation of phosphorus metabolic processGO:0010563800.018
negative regulation of nervous system developmentGO:0051961790.018
transmembrane transportGO:00550854120.018
proteolysisGO:00065081750.018
regulation of purine nucleotide metabolic processGO:19005421150.018
positive regulation of programmed cell deathGO:00430681570.018
organic hydroxy compound metabolic processGO:19016151150.018
regulation of cell projection organizationGO:00313441750.018
Rat
response to oxidative stressGO:00069791860.018
Rat
enzyme linked receptor protein signaling pathwayGO:00071671160.018
chemosensory behaviorGO:000763520.018
negative regulation of cellular biosynthetic processGO:00313271610.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
chemical homeostasisGO:00488782920.018
mapk cascadeGO:00001651400.018
response to woundingGO:00096112540.018
purine containing compound catabolic processGO:00725231380.018
neuromuscular processGO:005090520.017
single organism organelle organizationGO:19025891800.017
cellular response to external stimulusGO:00714961180.017
Rat
regulation of immune responseGO:0050776550.017
negative regulation of gene expressionGO:00106291990.017
cellular nitrogen compound catabolic processGO:00442701630.017
cellular response to peptide hormone stimulusGO:00713751200.017
circulatory system processGO:00030131830.017
endomembrane system organizationGO:0010256480.017
alcohol metabolic processGO:0006066770.017
positive regulation of multicellular organismal processGO:00512403870.017
Rat
cellular homeostasisGO:00197252520.017
developmental process involved in reproductionGO:00030061590.017
embryonic pattern specificationGO:000988010.016
cation transportGO:00068123820.016
signal releaseGO:00230611450.016
Rat
olfactory behaviorGO:004204820.016
actin filament based processGO:0030029860.016
single organism reproductive processGO:00447022970.016
immune responseGO:00069551040.016
rho protein signal transductionGO:0007266110.016
positive regulation of secretion by cellGO:19035321280.016
Rat
regulation of growthGO:00400081050.016
lipid localizationGO:0010876620.016
regulation of establishment of protein localizationGO:0070201690.016
response to biotic stimulusGO:00096072260.016
positive regulation of gene expressionGO:00106282440.016
metal ion transportGO:00300012890.016
axis specificationGO:000979840.016
cell part morphogenesisGO:00329901230.016
negative regulation of neuron differentiationGO:0045665620.015
synaptic transmissionGO:00072682350.015
Rat
dna metabolic processGO:0006259960.015
positive regulation of developmental processGO:00510942830.015
Rat
positive regulation of nucleotide metabolic processGO:0045981910.015
response to monosaccharideGO:00342841590.015
gtp metabolic processGO:0046039720.015
positive regulation of rna metabolic processGO:00512542030.015
regulation of protein kinase activityGO:00458591050.015
regulation of map kinase activityGO:0043405530.015
protein localization to membraneGO:0072657360.015
positive regulation of locomotionGO:00400171020.015
Rat
glycerophospholipid metabolic processGO:0006650470.015
negative regulation of developmental processGO:00510931250.015
multicellular organism growthGO:003526410.015
positive regulation of protein metabolic processGO:00512471780.015
Rat
cell morphogenesis involved in neuron differentiationGO:00486671060.015
regulation of protein serine threonine kinase activityGO:0071900640.015
positive regulation of immune system processGO:0002684900.015
negative regulation of immune system processGO:0002683390.015
response to extracellular stimulusGO:00099913800.015
Rat
multicellular organism reproductionGO:00325042330.015
Fly
regulation of leukocyte activationGO:0002694450.015
cellular response to stressGO:00335542690.015
Rat
defense responseGO:00069521940.015
response to reactive oxygen speciesGO:00003021200.015
Rat
positive regulation of cell differentiationGO:00455972170.014
Rat
positive regulation of nervous system developmentGO:00519621780.014
Rat
nucleoside monophosphate metabolic processGO:0009123930.014
negative regulation of biosynthetic processGO:00098901680.014
peptide transportGO:0015833970.014
regulation of nucleotide catabolic processGO:0030811650.014
lipid storageGO:001991510.014
positive regulation of neuron differentiationGO:00456661260.014
Rat
hemopoiesisGO:0030097340.014
positive regulation of secretionGO:00510471400.014
Rat
negative regulation of signalingGO:00230571570.014
cellular chemical homeostasisGO:00550822470.014
sterol homeostasisGO:005509230.014
negative regulation of macromolecule metabolic processGO:00106052600.014
cell morphogenesisGO:00009021420.014
gliogenesisGO:0042063930.014
biological adhesionGO:00226101100.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
regulation of response to external stimulusGO:00321011060.014
pallium developmentGO:0021543420.014
regulation of response to stressGO:00801341260.014
multicellular organismal reproductive processGO:00486092330.014
Fly
regulation of cell cycleGO:0051726730.014
agingGO:00075682410.014
negative regulation of cellular protein metabolic processGO:00322691060.013
divalent metal ion transportGO:00708381320.013
cell projection morphogenesisGO:00488581230.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
response to glucoseGO:00097491360.013
calcium ion transportGO:00068161310.013
negative regulation of innate immune responseGO:004582440.013
organ morphogenesisGO:0009887750.013
cellular response to nitrogen compoundGO:19016992100.013
circulatory system developmentGO:00723591340.013
response to temperature stimulusGO:0009266940.013
Yeast
response to oxygen levelsGO:00704822650.013
reproductive system developmentGO:00614581280.013
olfactory learningGO:000835510.013
regulation of hormone levelsGO:00108171870.013
positive regulation of cell motilityGO:2000147970.013
Rat
glial cell differentiationGO:0010001650.013
guanosine containing compound catabolic processGO:1901069710.013
regulation of cell migrationGO:00303341280.013
Rat
negative regulation of secretionGO:0051048820.013
maintenance of locationGO:0051235170.013
regulation of cell morphogenesisGO:0022604770.013
heart morphogenesisGO:000300730.012
sexual reproductionGO:00199531480.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
liver developmentGO:0001889900.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
organic anion transportGO:00157111320.012
regulation of gtp catabolic processGO:0033124580.012
positive regulation of cellular protein metabolic processGO:00322701670.012
Rat
nitrogen compound transportGO:00717052290.012
steroid metabolic processGO:0008202730.012
positive regulation of catabolic processGO:0009896780.012
positive regulation of signal transductionGO:00099671750.012
actin cytoskeleton organizationGO:0030036730.012
behaviorGO:00076102050.012
Fly
response to interleukin 1GO:0070555550.012
Rat
hepaticobiliary system developmentGO:0061008900.012
sulfur compound metabolic processGO:0006790700.012
response to other organismGO:00517072200.012
lipid transportGO:0006869610.012
ion homeostasisGO:00508012120.012
response to glucocorticoidGO:00513842230.012
negative regulation of cellular component organizationGO:0051129830.012
positive regulation of transferase activityGO:0051347810.012
regulation of rho gtpase activityGO:0032319170.012
regulation of gtpase activityGO:0043087570.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
response to peptide hormoneGO:00434342780.012
anion transmembrane transportGO:0098656770.012
cellular protein complex assemblyGO:0043623440.012
response to vitaminGO:00332731310.012
inorganic ion transmembrane transportGO:00986602290.012
asymmetric protein localizationGO:000810520.012
regulation of purine nucleotide catabolic processGO:0033121650.011
sex differentiationGO:00075481130.011
regulation of apoptotic processGO:00429813350.011
Rat
negative regulation of intracellular signal transductionGO:1902532380.011
tube developmentGO:0035295890.011
regulation of nucleoside metabolic processGO:0009118660.011
response to amino acidGO:0043200750.011
peptide secretionGO:0002790860.011
regulation of nucleotide metabolic processGO:00061401170.011
cellular response to peptideGO:19016531330.011
positive regulation of cell projection organizationGO:00313461110.011
Rat
cellular macromolecular complex assemblyGO:0034622580.011
positive regulation of hydrolase activityGO:0051345860.011
immune system developmentGO:0002520410.011
regulation of ras protein signal transductionGO:0046578450.011
cellular modified amino acid metabolic processGO:0006575610.011
divalent inorganic cation transportGO:00725111340.011
negative regulation of cell projection organizationGO:0031345500.011
gamete generationGO:00072761240.011
amide transportGO:00428861050.011
response to acid chemicalGO:00011012220.011
cholesterol homeostasisGO:004263230.011
response to ethanolGO:00454711620.011
epithelium developmentGO:0060429960.011
negative regulation of rna metabolic processGO:00512531230.011
regulation of vesicle mediated transportGO:0060627810.011
regulation of programmed cell deathGO:00430673410.011
Rat
regulation of lipid biosynthetic processGO:0046890380.011
cell morphogenesis involved in differentiationGO:00009041190.011
positive regulation of cellular catabolic processGO:0031331710.010
cellular amide metabolic processGO:0043603440.010
cofactor metabolic processGO:0051186950.010
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.010
embryo developmentGO:0009790490.010
cell activationGO:0001775970.010
regulation of membrane potentialGO:00423911100.010
gtp catabolic processGO:0006184710.010
regulation of anatomical structure sizeGO:00900661350.010

Sphk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.036
disease of anatomical entityDOID:700.036
musculoskeletal system diseaseDOID:1700.019
muscular diseaseDOID:008000000.016
muscle tissue diseaseDOID:6600.016
central nervous system diseaseDOID:33100.013
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
disease of metabolismDOID:001466700.012