Rattus norvegicus

228 known processes

Sphk1

sphingosine kinase 1

Sphk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic processGO:00069153810.105
response to extracellular stimulusGO:00099913800.098
response to cytokineGO:00340972150.093
response to peptideGO:19016522920.090
positive regulation of biosynthetic processGO:00098913190.084
cellular response to nitrogen compoundGO:19016992100.077
reproductive processGO:00224143720.073
positive regulation of response to stimulusGO:00485842850.067
Human
regulation of cell differentiationGO:00455953200.067
regulation of immunoglobulin productionGO:000263740.065
multicellular organismal reproductive processGO:00486092330.063
positive regulation of nitrogen compound metabolic processGO:00511733340.062
cellular response to endogenous stimulusGO:00714953770.060
tissue developmentGO:00098882520.057
regulation of cell motilityGO:20001451310.057
regulation of cellular localizationGO:00603412630.056
positive regulation of cellular biosynthetic processGO:00313282950.054
organic acid metabolic processGO:00060822920.052
regulation of rna biosynthetic processGO:20011413810.051
Human
cell projection organizationGO:00300303020.050
regulation of cell proliferationGO:00421273590.050
Human Mouse
regulation of cellular component organizationGO:00511283680.048
programmed cell deathGO:00125013920.047
cellular response to external stimulusGO:00714961180.046
response to lipopolysaccharideGO:00324961910.046
response to interleukin 1GO:0070555550.045
negative regulation of cellular metabolic processGO:00313242810.045
response to purine containing compoundGO:00140741260.044
anion transportGO:00068201780.044
response to nutrientGO:00075842480.043
behaviorGO:00076102050.042
regulation of molecular functionGO:00650093980.041
Human
inflammatory responseGO:00069541500.041
Mouse
cellular response to cytokine stimulusGO:00713451270.040
Human
transmembrane transportGO:00550854120.040
response to peptide hormoneGO:00434342780.040
rhythmic processGO:00485111560.040
regulation of apoptotic processGO:00429813350.039
anatomical structure formation involved in morphogenesisGO:0048646830.039
Human
reproductive structure developmentGO:00486081280.039
response to metal ionGO:00100382530.038
carboxylic acid metabolic processGO:00197522890.038
neuron developmentGO:00486662860.037
reproductionGO:00000032450.037
vesicle mediated transportGO:00161921810.036
regulation of phosphorus metabolic processGO:00511743490.036
cellular component assemblyGO:00226073600.035
secretionGO:00469033070.035
response to ketoneGO:19016541820.035
regulation of immune system processGO:00026821230.035
locomotionGO:00400112370.034
cell motilityGO:00488702020.034
secretion by cellGO:00329402480.033
response to molecule of bacterial originGO:00022371940.033
negative regulation of metabolic processGO:00098923310.033
transcription dna templatedGO:00063513770.033
Human
intracellular signal transductionGO:00355563140.033
Human Yeast
reproductive system developmentGO:00614581280.033
cellular response to oxygen containing compoundGO:19017013860.032
brain developmentGO:00074202470.032
Mouse
positive regulation of apoptotic processGO:00430651540.032
cellular homeostasisGO:00197252520.032
cellular response to interleukin 1GO:0071347370.032
regulation of cell developmentGO:00602842630.032
defense responseGO:00069521940.031
Mouse
response to organophosphorusGO:00466831020.031
positive regulation of immune system processGO:0002684900.031
negative regulation of macromolecule metabolic processGO:00106052600.030
regulation of cellular component movementGO:00512701500.030
intracellular transportGO:00469071850.030
Human
ovulation cycle processGO:0022602500.030
positive regulation of macromolecule biosynthetic processGO:00105572470.029
response to campGO:0051591910.028
response to insulinGO:00328681330.028
immune responseGO:00069551040.028
regulation of response to stressGO:00801341260.028
angiogenesisGO:0001525530.028
Human
negative regulation of gene expressionGO:00106291990.028
response to corticosteroidGO:00319602350.028
response to acid chemicalGO:00011012220.028
positive regulation of multicellular organismal processGO:00512403870.027
negative regulation of protein metabolic processGO:00512481140.027
regulation of immunoglobulin secretionGO:005102310.027
regulation of locomotionGO:00400121480.027
regulation of cellular amino acid metabolic processGO:000652120.027
response to external biotic stimulusGO:00432072210.027
nucleic acid templated transcriptionGO:00976593790.026
Human
single organism reproductive processGO:00447022970.026
regulation of response to woundingGO:1903034690.026
ras protein signal transductionGO:0007265290.026
cellular amino acid metabolic processGO:00065201070.026
regulation of g0 to g1 transitionGO:007031630.026
positive regulation of immunoglobulin productionGO:000263940.026
regulation of cell projection organizationGO:00313441750.026
response to carbohydrateGO:00097431830.026
lipid biosynthetic processGO:00086101280.026
positive regulation of programmed cell deathGO:00430681570.025
regulation of catalytic activityGO:00507903040.025
regulation of protein metabolic processGO:00512462890.025
regulation of transcription dna templatedGO:00063553740.025
Human
regulation of neuron differentiationGO:00456642080.025
response to radiationGO:00093141370.025
organelle organizationGO:00069962660.025
regulation of response to external stimulusGO:00321011060.025
agingGO:00075682410.025
protein complex biogenesisGO:00702712630.024
regulation of cellular ketone metabolic processGO:0010565270.024
single organism behaviorGO:00447081300.024
response to monosaccharideGO:00342841590.024
response to transition metal nanoparticleGO:19902671220.024
cellular ketone metabolic processGO:0042180510.024
protein complex subunit organizationGO:00718223020.024
protein transportGO:00150311320.024
Human
neuron differentiationGO:00301823680.024
cellular amine metabolic processGO:0044106380.023
female gonad developmentGO:0008585530.023
regulation of programmed cell deathGO:00430673410.023
regulation of signal transductionGO:00099663180.023
Human
metal ion transportGO:00300012890.023
cellular component biogenesisGO:00440853680.023
cellular chemical homeostasisGO:00550822470.023
positive regulation of cell migrationGO:0030335960.023
immune system processGO:00023762040.023
regulation of phosphate metabolic processGO:00192203490.023
macromolecule localizationGO:00330362520.023
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
cell cell signalingGO:00072673350.022
positive regulation of phosphate metabolic processGO:00459372620.022
cellular response to organonitrogen compoundGO:00714171970.022
regulation of cellular protein metabolic processGO:00322682670.022
protein homooligomerizationGO:0051260910.022
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
positive regulation of cell differentiationGO:00455972170.022
macromolecular complex subunit organizationGO:00439333390.022
proteolysisGO:00065081750.021
rna metabolic processGO:00160704060.021
Human
protein complex assemblyGO:00064612630.021
response to transforming growth factor betaGO:0071559460.021
regulation of multicellular organismal developmentGO:20000263760.021
anatomical structure morphogenesisGO:00096532980.021
Human
positive regulation of gene expressionGO:00106282440.021
positive regulation of cell proliferationGO:00082842490.021
Human Mouse
biological adhesionGO:00226101100.021
nitrogen compound transportGO:00717052290.021
Human
regulation of protein maturationGO:1903317500.020
gonad developmentGO:00084061040.020
ion homeostasisGO:00508012120.020
cellular response to tumor necrosis factorGO:0071356460.020
Human
regulation of leukocyte migrationGO:0002685240.020
response to tumor necrosis factorGO:0034612560.020
Human
cellular response to hormone stimulusGO:00328702470.020
ion transmembrane transportGO:00342203650.020
single organism intracellular transportGO:19025821660.020
Human
macromolecular complex assemblyGO:00650032730.019
cation homeostasisGO:00550801950.019
response to hexoseGO:00097461440.019
protein oligomerizationGO:00512591910.019
regulation of immunoglobulin mediated immune responseGO:000288920.019
small gtpase mediated signal transductionGO:0007264360.019
chemical homeostasisGO:00488782920.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
organic substance catabolic processGO:19015753160.019
positive regulation of cellular amine metabolic processGO:003324030.019
positive regulation of catalytic activityGO:00430851840.019
response to ammonium ionGO:0060359710.019
anterior posterior pattern specificationGO:000995210.019
cellular response to stressGO:00335542690.019
reactive oxygen species metabolic processGO:0072593370.019
unsaturated fatty acid metabolic processGO:0033559390.019
multicellular organism reproductionGO:00325042330.018
regulation of intracellular signal transductionGO:19025312180.018
Human
positive regulation of defense responseGO:0031349370.018
response to oxygen levelsGO:00704822650.018
regulation of anatomical structure sizeGO:00900661350.018
muscle contractionGO:0006936880.018
Human
positive regulation of cell motilityGO:2000147970.017
circulatory system developmentGO:00723591340.017
Human Mouse
anion transmembrane transportGO:0098656770.017
development of primary sexual characteristicsGO:00451371070.017
endocytosisGO:0006897840.017
protein localizationGO:00081041910.017
Human
regulation of system processGO:00440572080.017
Human
response to inorganic substanceGO:00100353770.017
positive regulation of signal transductionGO:00099671750.017
Human
cellular response to organic cyclic compoundGO:00714072020.017
cellular component movementGO:00069282480.016
cellular response to lipidGO:00713962010.016
positive regulation of cellular component movementGO:00512721020.016
response to estrogenGO:00436272320.016
regulation of cellular amine metabolic processGO:003323880.016
neuron projection developmentGO:00311752730.016
regulation of nervous system developmentGO:00519602640.016
protein phosphorylationGO:00064683450.016
negative regulation of protein maturationGO:1903318470.016
vitamin transportGO:0051180140.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
negative regulation of cell proliferationGO:00082851190.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
regulation of peptidase activityGO:0052547550.016
regulation of canonical wnt signaling pathwayGO:006082840.016
divalent inorganic cation transportGO:00725111340.016
negative regulation of programmed cell deathGO:00430691830.016
response to decreased oxygen levelsGO:00362932370.015
regulation of hydrolase activityGO:00513361430.015
negative regulation of cellular protein metabolic processGO:00322691060.015
cation transportGO:00068123820.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
negative regulation of multicellular organismal processGO:00512412030.015
sex differentiationGO:00075481130.015
positive regulation of secretion by cellGO:19035321280.015
metal ion homeostasisGO:00550651860.015
transcription from rna polymerase ii promoterGO:00063662520.015
negative regulation of molecular functionGO:00440921330.015
negative regulation of protein processingGO:0010955470.015
amine metabolic processGO:0009308380.015
development of primary female sexual characteristicsGO:0046545560.015
immunoglobulin secretionGO:004830510.015
positive regulation of transcription dna templatedGO:00458931970.014
regulation of secretion by cellGO:19035302080.014
developmental process involved in reproductionGO:00030061590.014
negative regulation of endopeptidase activityGO:0010951360.014
response to nutrient levelsGO:00316673700.014
negative regulation of peptidase activityGO:0010466380.014
regulation of blood circulationGO:19035221100.014
response to vitaminGO:00332731310.014
regulation of proteolysisGO:0030162660.014
organic acid transportGO:00158491160.014
catabolic processGO:00090563510.014
multi multicellular organism processGO:00447061380.014
growthGO:00400071650.014
Human
positive regulation of cell deathGO:00109421840.014
positive regulation of cell communicationGO:00106472710.014
central nervous system developmentGO:00074173110.014
Mouse
regulation of anatomical structure morphogenesisGO:00226031410.014
Human
axis specificationGO:000979840.014
response to woundingGO:00096112540.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
cellular response to peptideGO:19016531330.014
regulation of secretionGO:00510462240.014
response to hypoxiaGO:00016662310.014
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.013
male gonad developmentGO:0008584590.013
divalent inorganic cation homeostasisGO:00725071650.013
female pregnancyGO:00075651220.013
cellular calcium ion homeostasisGO:00068741600.013
negative regulation of response to stimulusGO:00485851550.013
response to other organismGO:00517072200.013
nucleobase containing small molecule metabolic processGO:00550863160.013
male sex differentiationGO:0046661640.013
cellular response to peptide hormone stimulusGO:00713751200.013
response to growth factorGO:00708481890.013
salivary gland developmentGO:000743130.013
negative regulation of biosynthetic processGO:00098901680.013
negative regulation of catalytic activityGO:00430861030.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
response to ethanolGO:00454711620.013
positive regulation of rna biosynthetic processGO:19026801970.013
positive regulation of developmental processGO:00510942830.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
carbohydrate derivative metabolic processGO:19011353460.013
muscle structure developmentGO:0061061870.013
regulation of defense responseGO:0031347680.013
positive regulation of g0 to g1 transitionGO:007031820.013
negative regulation of neuron differentiationGO:0045665620.013
rna biosynthetic processGO:00327743800.013
Human
negative regulation of proteolysisGO:0045861410.013
regulation of endocytosisGO:0030100420.013
response to hydrogen peroxideGO:0042542890.013
regulation of protein processingGO:0070613500.013
nucleoside metabolic processGO:00091161790.013
circulatory system processGO:00030131830.012
cardiac chamber developmentGO:000320510.012
negative regulation of cell deathGO:00605482290.012
response to glucoseGO:00097491360.012
protein maturationGO:0051604680.012
extracellular matrix constituent secretionGO:007027840.012
positive regulation of molecular functionGO:00440932300.012
Human
regulation of hormone levelsGO:00108171870.012
muscle system processGO:00030121150.012
Human
tissue remodelingGO:0048771400.012
transmission of nerve impulseGO:0019226420.012
cytoplasmic transportGO:00164821150.012
Human
regulation of ion transportGO:00432692450.012
cell adhesionGO:00071551100.012
synaptic transmissionGO:00072682350.012
positive regulation of rna metabolic processGO:00512542030.012
regulation of nucleotide metabolic processGO:00061401170.012
intracellular protein transportGO:0006886790.012
Human
regulation of rna metabolic processGO:00512523910.012
Human
negative regulation of phosphate metabolic processGO:0045936800.012
oxoacid metabolic processGO:00434362900.012
reactive oxygen species biosynthetic processGO:190340980.011
pseudopodium organizationGO:003126830.011
gland developmentGO:00487321550.011
positive regulation of phosphorylationGO:00423271770.011
response to mechanical stimulusGO:00096121340.011
head developmentGO:00603222470.011
Mouse
lipid metabolic processGO:00066292830.011
leukocyte migrationGO:0050900380.011
cellular response to mechanical stimulusGO:0071260480.011
regulation of neurogenesisGO:00507672470.011
neuronal action potentialGO:0019228350.011
regulation of cell migrationGO:00303341280.011
cytokine mediated signaling pathwayGO:0019221430.011
Human
response to nicotineGO:0035094510.011
molting cycle processGO:002240420.011
heart morphogenesisGO:000300730.011
response to ionizing radiationGO:0010212590.011
activation of cysteine type endopeptidase activityGO:009720240.011
amino acid transmembrane transportGO:0003333330.011
vitamin d metabolic processGO:004235940.011
positive regulation of protein metabolic processGO:00512471780.011
positive regulation of neurogenesisGO:00507691650.011
response to bacteriumGO:00096172000.011
neuron deathGO:00709971270.011
divalent metal ion transportGO:00708381320.011
monovalent inorganic cation transportGO:00156721720.011
regulation of angiogenesisGO:0045765390.011
Human
mesoderm developmentGO:000749820.011
cellular metal ion homeostasisGO:00068751720.011
blood circulationGO:00080151830.011
regulation of endopeptidase activityGO:0052548510.011
cellular lipid metabolic processGO:00442552080.010
positive regulation of neuron differentiationGO:00456661260.010
calcium ion transportGO:00068161310.010
positive regulation of cell projection organizationGO:00313461110.010
blood vessel developmentGO:0001568690.010
Human Mouse
positive regulation of intracellular signal transductionGO:19025331380.010
Human
action potentialGO:0001508540.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
protein heterooligomerizationGO:0051291890.010
response to oxidative stressGO:00069791860.010
negative regulation of cellular biosynthetic processGO:00313271610.010
development of primary male sexual characteristicsGO:0046546590.010
positive regulation of transportGO:00510502450.010
regulation of protein modification processGO:00313991940.010
reactive nitrogen species metabolic processGO:200105710.010
positive regulation of cardiac muscle contractionGO:006045240.010
nucleotide metabolic processGO:00091172790.010
neuron neuron synaptic transmissionGO:0007270600.010
regulation of phosphorylationGO:00423252480.010
positive regulation of behaviorGO:0048520380.010
cellular response to alcoholGO:0097306870.010
positive regulation of ion transportGO:0043270940.010

Sphk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
central nervous system diseaseDOID:33100.016