Rattus norvegicus

34 known processes

Doc2a

double C2-like domains, alpha

Doc2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signalingGO:00072673350.202
neurological system processGO:00508772190.098
cell motilityGO:00488702020.096
localization of cellGO:00516742020.086
regulation of phosphate metabolic processGO:00192203490.080
secretion by cellGO:00329402480.079
cell projection organizationGO:00300303020.078
regulation of multicellular organismal developmentGO:20000263760.076
single organism reproductive processGO:00447022970.074
Worm
programmed cell deathGO:00125013920.070
regulation of cellular localizationGO:00603412630.069
Human Mouse
cellular component assemblyGO:00226073600.067
regulation of hormone levelsGO:00108171870.066
regulation of cellular component organizationGO:00511283680.063
neuron differentiationGO:00301823680.062
neuron developmentGO:00486662860.061
secretionGO:00469033070.060
rna biosynthetic processGO:00327743800.060
regulation of secretion by cellGO:19035302080.058
Human Mouse
regulation of secretionGO:00510462240.058
Human Mouse
regulation of protein modification processGO:00313991940.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.056
hormone transportGO:00099141210.056
central nervous system developmentGO:00074173110.056
Rat
regulation of molecular functionGO:00650093980.055
regulation of programmed cell deathGO:00430673410.055
regulation of nucleic acid templated transcriptionGO:19035063800.055
positive regulation of nitrogen compound metabolic processGO:00511733340.055
regulation of cell differentiationGO:00455953200.054
response to peptide hormoneGO:00434342780.053
apoptotic processGO:00069153810.051
synaptic transmissionGO:00072682350.051
metal ion transportGO:00300012890.050
negative regulation of metabolic processGO:00098923310.050
response to monosaccharideGO:00342841590.050
macromolecule localizationGO:00330362520.049
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.049
positive regulation of phosphate metabolic processGO:00459372620.049
regulation of cell proliferationGO:00421273590.048
regulation of locomotionGO:00400121480.048
Worm
cellular component biogenesisGO:00440853680.048
regulation of cellular component movementGO:00512701500.047
regulation of system processGO:00440572080.047
regulation of apoptotic processGO:00429813350.046
signal releaseGO:00230611450.046
regulation of protein phosphorylationGO:00019321830.046
neuron projection developmentGO:00311752730.046
peptide secretionGO:0002790860.045
protein localizationGO:00081041910.045
macromolecular complex subunit organizationGO:00439333390.044
homeostatic processGO:00425923310.044
multi organism reproductive processGO:00447032620.044
regulation of ion transportGO:00432692450.043
anatomical structure morphogenesisGO:00096532980.043
positive regulation of phosphorus metabolic processGO:00105622620.043
macromolecular complex assemblyGO:00650032730.043
protein phosphorylationGO:00064683450.042
rhythmic processGO:00485111560.042
positive regulation of transportGO:00510502450.042
positive regulation of multicellular organismal processGO:00512403870.042
regulation of rna biosynthetic processGO:20011413810.041
regulation of rna metabolic processGO:00512523910.041
positive regulation of developmental processGO:00510942830.041
positive regulation of protein phosphorylationGO:00019341350.041
protein complex biogenesisGO:00702712630.041
regulation of hormone secretionGO:00468831060.039
locomotionGO:00400112370.039
Worm
cellular calcium ion homeostasisGO:00068741600.039
positive regulation of nucleic acid templated transcriptionGO:19035081970.039
regulation of phosphorylationGO:00423252480.038
response to inorganic substanceGO:00100353770.038
single organism behaviorGO:00447081300.038
regulation of neuron differentiationGO:00456642080.038
cellular response to nitrogen compoundGO:19016992100.037
cellular response to oxygen containing compoundGO:19017013860.037
ion transmembrane transportGO:00342203650.037
regulation of phosphorus metabolic processGO:00511743490.037
positive regulation of phosphorylationGO:00423271770.037
cellular component movementGO:00069282480.037
cation transportGO:00068123820.037
organophosphate biosynthetic processGO:00904071430.036
response to estrogenGO:00436272320.036
regulation of nervous system developmentGO:00519602640.036
nitrogen compound transportGO:00717052290.035
negative regulation of cellular metabolic processGO:00313242810.035
g protein coupled receptor signaling pathwayGO:00071862420.035
rna metabolic processGO:00160704060.034
response to glucocorticoidGO:00513842230.034
response to hexoseGO:00097461440.034
hormone secretionGO:00468791150.034
cellular amine metabolic processGO:0044106380.033
protein oligomerizationGO:00512591910.033
regulation of peptide hormone secretionGO:0090276800.033
response to molecule of bacterial originGO:00022371940.033
regulation of transcription from rna polymerase ii promoterGO:00063572340.033
transcription from rna polymerase ii promoterGO:00063662520.033
anterior posterior pattern specificationGO:000995210.033
reproductive processGO:00224143720.033
Worm
positive regulation of biosynthetic processGO:00098913190.032
positive regulation of nervous system developmentGO:00519621780.032
regulation of neurogenesisGO:00507672470.032
brain developmentGO:00074202470.032
Rat
regulation of membrane potentialGO:00423911100.032
cellular ketone metabolic processGO:0042180510.032
cellular component morphogenesisGO:00329891550.032
response to extracellular stimulusGO:00099913800.032
protein heterooligomerizationGO:0051291890.032
cellular divalent inorganic cation homeostasisGO:00725031620.032
positive regulation of cell proliferationGO:00082842490.032
response to mechanical stimulusGO:00096121340.032
organic acid metabolic processGO:00060822920.031
carboxylic acid metabolic processGO:00197522890.031
response to growth factorGO:00708481890.031
regulation of catalytic activityGO:00507903040.031
positive regulation of cell differentiationGO:00455972170.031
positive regulation of molecular functionGO:00440932300.031
transmembrane transportGO:00550854120.031
multicellular organismal reproductive processGO:00486092330.031
regulation of transcription dna templatedGO:00063553740.031
protein complex assemblyGO:00064612630.031
positive regulation of cell developmentGO:00107201760.030
regulation of cellular protein metabolic processGO:00322682670.030
response to carbohydrateGO:00097431830.030
cellular homeostasisGO:00197252520.030
positive regulation of gene expressionGO:00106282440.030
positive regulation of rna biosynthetic processGO:19026801970.030
cell part morphogenesisGO:00329901230.030
response to glucoseGO:00097491360.030
protein complex subunit organizationGO:00718223020.030
chemical homeostasisGO:00488782920.030
cellular response to organic cyclic compoundGO:00714072020.030
cell migrationGO:00164771970.029
peptide transportGO:0015833970.029
cellular chemical homeostasisGO:00550822470.029
reproductionGO:00000032450.029
regulation of cell migrationGO:00303341280.028
ion homeostasisGO:00508012120.028
immune system processGO:00023762040.028
regulation of cellular ketone metabolic processGO:0010565270.028
regulation of cell developmentGO:00602842630.028
regulation of cell motilityGO:20001451310.028
amine metabolic processGO:0009308380.028
response to peptideGO:19016522920.028
negative regulation of apoptotic processGO:00430661810.028
vesicle mediated transportGO:00161921810.028
gland developmentGO:00487321550.028
oxoacid metabolic processGO:00434362900.028
regulation of peptide transportGO:0090087870.028
regulation of protein metabolic processGO:00512462890.028
divalent inorganic cation homeostasisGO:00725071650.028
cell projection morphogenesisGO:00488581230.028
multicellular organism reproductionGO:00325042330.028
regenerationGO:00310991630.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
nucleobase containing small molecule metabolic processGO:00550863160.027
asymmetric protein localizationGO:000810520.027
lipid metabolic processGO:00066292830.027
nucleic acid templated transcriptionGO:00976593790.027
response to corticosteroidGO:00319602350.026
organonitrogen compound biosynthetic processGO:19015661670.026
synaptic growth at neuromuscular junctionGO:005112410.026
cellular response to hormone stimulusGO:00328702470.026
purine containing compound metabolic processGO:00725212530.026
negative regulation of programmed cell deathGO:00430691830.026
enzyme linked receptor protein signaling pathwayGO:00071671160.026
regulation of synaptic growth at neuromuscular junctionGO:000858210.026
growthGO:00400071650.026
anion transportGO:00068201780.026
response to metal ionGO:00100382530.026
organophosphate metabolic processGO:00196373700.026
response to woundingGO:00096112540.025
negative regulation of biosynthetic processGO:00098901680.025
purine ribonucleotide biosynthetic processGO:0009152810.025
negative regulation of multicellular organismal processGO:00512412030.025
positive regulation of protein modification processGO:00314011420.025
response to decreased oxygen levelsGO:00362932370.025
reproductive system developmentGO:00614581280.025
Worm
cellular ion homeostasisGO:00068731840.025
positive regulation of protein metabolic processGO:00512471780.025
positive regulation of cell communicationGO:00106472710.025
positive regulation of cellular biosynthetic processGO:00313282950.024
cellular amino acid metabolic processGO:00065201070.024
ribose phosphate metabolic processGO:00196932350.024
embryonic pattern specificationGO:000988010.024
single organism biosynthetic processGO:00447113420.024
regulation of peptide secretionGO:0002791820.024
positive regulation of rna metabolic processGO:00512542030.024
cognitionGO:0050890920.024
catabolic processGO:00090563510.024
positive regulation of transcription dna templatedGO:00458931970.024
positive regulation of response to stimulusGO:00485842850.024
peptide hormone secretionGO:0030072840.024
glomerular epithelial cell differentiationGO:007231120.024
axis specificationGO:000979840.024
carbohydrate derivative metabolic processGO:19011353460.024
positive regulation of cytosolic calcium ion concentrationGO:00072041220.024
negative regulation of nucleobase containing compound metabolic processGO:00459341530.024
cell fate determinationGO:000170920.023
locomotor rhythmGO:004547510.023
intracellular transportGO:00469071850.023
positive regulation of cell motilityGO:2000147970.023
response to estradiolGO:00323551640.023
regulation of cellular amine metabolic processGO:003323880.023
camp metabolic processGO:0046058630.023
positive regulation of secretionGO:00510471400.023
positive regulation of neuron projection developmentGO:0010976990.023
cation transmembrane transportGO:00986552630.023
organic substance catabolic processGO:19015753160.023
cellular response to steroid hormone stimulusGO:0071383930.023
male mating behaviorGO:006017930.023
action potentialGO:0001508540.022
cellular response to organonitrogen compoundGO:00714171970.022
regulation of transmembrane transportGO:00347621220.022
regulation of growthGO:00400081050.022
heart morphogenesisGO:000300730.022
cellular macromolecule localizationGO:00707271220.022
single organism organelle organizationGO:19025891800.022
learning or memoryGO:0007611900.022
negative regulation of transportGO:00510511360.022
positive regulation of ion transportGO:0043270940.022
circulatory system processGO:00030131830.022
regulation of cellular amino acid metabolic processGO:000652120.022
positive regulation of cell deathGO:00109421840.022
intracellular signal transductionGO:00355563140.022
response to nutrient levelsGO:00316673700.022
negative regulation of neurogenesisGO:0050768780.022
developmental growthGO:00485891000.021
mesoderm developmentGO:000749820.021
divalent inorganic cation transportGO:00725111340.021
chromosome segregationGO:000705920.021
negative regulation of macromolecule metabolic processGO:00106052600.021
regulation of synaptic transmissionGO:00508041410.021
cytosolic calcium ion homeostasisGO:00514801400.021
gastrulationGO:000736920.021
cell morphogenesisGO:00009021420.021
bmp signaling pathwayGO:003050940.021
wound healingGO:00420601220.020
response to radiationGO:00093141370.020
negative regulation of cell deathGO:00605482290.020
positive regulation of signalingGO:00230562700.020
ribonucleotide biosynthetic processGO:0009260850.020
ribonucleotide metabolic processGO:00092592310.020
cyclic nucleotide metabolic processGO:0009187800.020
regulation of anatomical structure sizeGO:00900661350.020
developmental process involved in reproductionGO:00030061590.020
Worm
positive regulation of catalytic activityGO:00430851840.020
gonad developmentGO:00084061040.020
Worm
positive regulation of cellular component organizationGO:00511302000.020
calcium ion homeostasisGO:00550741620.020
proteolysisGO:00065081750.020
negative regulation of cell proliferationGO:00082851190.020
cellular response to growth factor stimulusGO:00713631620.020
cell adhesionGO:00071551100.020
negative regulation of transcription dna templatedGO:00458921160.020
amide transportGO:00428861050.020
cardiovascular system developmentGO:00723581340.020
positive regulation of cellular amine metabolic processGO:003324030.020
positive regulation of neurogenesisGO:00507691650.019
blood circulationGO:00080151830.019
nucleoside phosphate metabolic processGO:00067532830.019
sensory perceptionGO:00076001010.019
regulation of signal transductionGO:00099663180.019
response to oxygen levelsGO:00704822650.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.019
cellular cation homeostasisGO:00300031800.019
inorganic ion transmembrane transportGO:00986602290.019
carboxylic acid transportGO:00469421150.019
signal transduction by phosphorylationGO:00230141440.019
phospholipid metabolic processGO:0006644610.019
response to organophosphorusGO:00466831020.019
renal system developmentGO:0072001670.019
phosphatidylinositol dephosphorylationGO:004685640.019
cell type specific apoptotic processGO:00972851340.018
cardiac chamber developmentGO:000320510.018
response to alkaloidGO:00432791320.018
positive regulation of cellular protein metabolic processGO:00322701670.018
ribonucleoside metabolic processGO:00091191740.018
spermatogenesisGO:0007283990.018
behaviorGO:00076102050.018
nucleotide metabolic processGO:00091172790.018
organelle organizationGO:00069962660.018
gamete generationGO:00072761240.017
purine containing compound biosynthetic processGO:0072522850.017
response to ketoneGO:19016541820.017
cation homeostasisGO:00550801950.017
response to bacteriumGO:00096172000.017
gliogenesisGO:0042063930.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
nucleoside metabolic processGO:00091161790.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
negative regulation of secretionGO:0051048820.017
glycosyl compound metabolic processGO:19016571820.017
cardiac ventricle developmentGO:000323110.017
purine nucleotide metabolic processGO:00061632290.017
neuron neuron synaptic transmissionGO:0007270600.017
dna metabolic processGO:0006259960.017
sexual reproductionGO:00199531480.017
transcription dna templatedGO:00063513770.017
insulin secretionGO:0030073690.017
positive regulation of homeostatic processGO:0032846490.017
single organism catabolic processGO:00447122830.017
tissue developmentGO:00098882520.017
single organism intracellular transportGO:19025821660.017
cellular response to endogenous stimulusGO:00714953770.017
positive regulation of protein kinase activityGO:0045860730.017
response to acid chemicalGO:00011012220.017
metal ion homeostasisGO:00550651860.017
positive regulation of signal transductionGO:00099671750.016
male gamete generationGO:0048232990.016
organ regenerationGO:00311001010.016
monovalent inorganic cation transportGO:00156721720.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
response to lipopolysaccharideGO:00324961910.016
carbohydrate homeostasisGO:0033500750.016
urogenital system developmentGO:0001655780.016
regulation of cyclic nucleotide metabolic processGO:0030799510.016
regulation of neuron projection developmentGO:00109751610.016
multicellular organism growthGO:003526410.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.016
positive regulation of neuron differentiationGO:00456661260.016
regulation of kinase activityGO:00435491170.016
inorganic cation transmembrane transportGO:00986622020.016
negative regulation of response to stimulusGO:00485851550.016
cell cycleGO:00070491010.016
cellular response to cytokine stimulusGO:00713451270.016
monocarboxylic acid metabolic processGO:00327871520.016
agingGO:00075682410.016
cell growthGO:00160491040.016
regulation of homeostatic processGO:00328441010.016
neuron fate commitmentGO:004866340.015
cell cell signaling involved in cell fate commitmentGO:004516820.015
sequestering of calcium ionGO:005120880.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
organic hydroxy compound metabolic processGO:19016151150.015
regulation of purine nucleotide metabolic processGO:19005421150.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
small gtpase mediated signal transductionGO:0007264360.015
negative regulation of mitotic cell cycle phase transitionGO:190199130.015
protein localization to membraneGO:0072657360.015
chemosensory behaviorGO:000763520.015
adult locomotory behaviorGO:000834440.015
ribonucleotide catabolic processGO:00092611360.015
neuron projection morphogenesisGO:00488121220.015
cellular response to hexose stimulusGO:0071331650.015
nucleotide biosynthetic processGO:0009165980.015
circadian rhythmGO:0007623880.015
cellular response to peptideGO:19016531330.015
lipid biosynthetic processGO:00086101280.015
organic acid transportGO:00158491160.015
multicellular organismal signalingGO:0035637440.015
negative regulation of secretion by cellGO:1903531720.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
neuromuscular synaptic transmissionGO:000727420.015
positive regulation of secretion by cellGO:19035321280.015
regulation of blood circulationGO:19035221100.015
purine ribonucleoside metabolic processGO:00461281680.014
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.014
cell morphogenesis involved in differentiationGO:00009041190.014
cellular response to glucocorticoid stimulusGO:0071385680.014
cellular metal ion homeostasisGO:00068751720.014
protein transportGO:00150311320.014
negative regulation of signalingGO:00230571570.014
calcium ion transportGO:00068161310.014
negative regulation of vesicle fusionGO:003133920.014
negative regulation of gene expressionGO:00106291990.014
appendage morphogenesisGO:003510740.014
negative regulation of phosphate metabolic processGO:0045936800.014
neuronal action potentialGO:0019228350.014
negative regulation of phosphorus metabolic processGO:0010563800.014
purine ribonucleotide metabolic processGO:00091502270.014
sequestering of metal ionGO:005123890.014
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.014
establishment of vesicle localizationGO:0051650310.014
nucleoside triphosphate metabolic processGO:00091411440.014
negative regulation of cellular biosynthetic processGO:00313271610.014
establishment of protein localizationGO:00451841410.014
regulation of blood vessel sizeGO:0050880890.014
response to oxidative stressGO:00069791860.014
regulation of metal ion transportGO:00109591180.014
negative regulation of cellular component organizationGO:0051129830.013
regulation of body fluid levelsGO:0050878900.013
glycerolipid metabolic processGO:0046486670.013
regulation of nucleotide biosynthetic processGO:0030808470.013
regulation of cell projection organizationGO:00313441750.013
cellular response to alcoholGO:0097306870.013
negative regulation of cell communicationGO:00106481580.013
reproductive structure developmentGO:00486081280.013
Worm
endomembrane system organizationGO:0010256480.013
regulation of nucleotide metabolic processGO:00061401170.013
regulation of neuronal synaptic plasticityGO:0048168310.013
organonitrogen compound catabolic processGO:19015651790.013
cellular nitrogen compound catabolic processGO:00442701630.013
regulation of anatomical structure morphogenesisGO:00226031410.013
epithelium developmentGO:0060429960.013
cellular response to lipidGO:00713962010.013
hepaticobiliary system developmentGO:0061008900.013
purine nucleoside catabolic processGO:00061521240.013
eye morphogenesisGO:004859240.013
regulation of insulin secretionGO:0050796650.013
positive regulation of peptide secretionGO:0002793520.013
olfactory behaviorGO:004204820.013
purine nucleotide biosynthetic processGO:0006164830.013
cyclic nucleotide biosynthetic processGO:0009190630.013
carbohydrate derivative biosynthetic processGO:19011371240.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
positive regulation of programmed cell deathGO:00430681570.013
synaptic transmission glutamatergicGO:0035249330.013
ribose phosphate biosynthetic processGO:0046390870.013
negative regulation of cell differentiationGO:0045596990.013
rho protein signal transductionGO:0007266110.013
positive regulation of hormone secretionGO:0046887650.012
cytoplasmic transportGO:00164821150.012
single organism carbohydrate metabolic processGO:00447231180.012
dna packagingGO:000632340.012
glomerular mesangium developmentGO:007210940.012
circulatory system developmentGO:00723591340.012
nucleoside phosphate catabolic processGO:19012921400.012
vasculature developmentGO:0001944700.012
forebrain developmentGO:0030900980.012
cyclic purine nucleotide metabolic processGO:0052652620.012
response to nutrientGO:00075842480.012
protein homooligomerizationGO:0051260910.012
carbohydrate derivative catabolic processGO:19011361470.012
positive regulation of locomotionGO:00400171020.012
Worm
rna localizationGO:000640340.012
meiotic cell cycle processGO:190304630.012
actin filament based processGO:0030029860.012
single organism cellular localizationGO:19025801020.012
response to ethanolGO:00454711620.012
peptidyl amino acid modificationGO:00181931260.012
response to cytokineGO:00340972150.012
sex differentiationGO:00075481130.012
Worm
regulation of transmembrane transporter activityGO:0022898490.012
negative regulation of cell developmentGO:0010721820.012
head developmentGO:00603222470.012
Rat
detection of calcium ionGO:000551310.012
regulation of purine nucleotide biosynthetic processGO:1900371460.012
ovulation cycleGO:0042698670.012
negative regulation of molecular functionGO:00440921330.012
cellular response to glucose stimulusGO:0071333650.012
epithelial cell differentiationGO:0030855710.012
regulation of hydrolase activityGO:00513361430.012
leukocyte activationGO:0045321760.012
formation of primary germ layerGO:000170410.012
positive regulation of nucleotide metabolic processGO:0045981910.012
regulation of ion homeostasisGO:2000021630.012
regulation of notch signaling pathwayGO:000859330.012
regulation of bmp signaling pathwayGO:003051020.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
positive regulation of cyclic nucleotide metabolic processGO:0030801370.011
cellular response to stressGO:00335542690.011
positive regulation of cell projection organizationGO:00313461110.011
response to hypoxiaGO:00016662310.011
cellular lipid metabolic processGO:00442552080.011
vasculogenesisGO:000157030.011
mitotic cell cycle processGO:1903047350.011
heterocycle catabolic processGO:00467001670.011
negative regulation of signal transductionGO:0009968830.011
regulation of neuron deathGO:19012141150.011
regulation of protein localizationGO:0032880810.011
regulation of intracellular signal transductionGO:19025312180.011
regulation of ion transmembrane transportGO:00347651210.011
cardiac muscle tissue morphogenesisGO:005500810.011
regulation of transferase activityGO:00513381230.011
negative regulation of developmental processGO:00510931250.011
nucleotide catabolic processGO:00091661390.011
negative regulation of cardiac muscle tissue developmentGO:005502630.011
limb morphogenesisGO:003510840.011
response to external biotic stimulusGO:00432072210.011
regulation of protein kinase activityGO:00458591050.011
development of primary sexual characteristicsGO:00451371070.011
Worm
purine containing compound catabolic processGO:00725231380.011
positive regulation of cellular component movementGO:00512721020.011
potassium ion transportGO:0006813970.011
ras protein signal transductionGO:0007265290.011
male sex differentiationGO:0046661640.011
response to calcium ionGO:0051592590.011
negative regulation of rna metabolic processGO:00512531230.011
positive regulation of apoptotic processGO:00430651540.011
heart contractionGO:0060047570.011
learningGO:0007612330.011
sensory organ developmentGO:0007423740.011
liver developmentGO:0001889900.011
negative regulation of protein metabolic processGO:00512481140.011

Doc2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.022
musculoskeletal system diseaseDOID:1700.022
muscle tissue diseaseDOID:6600.022
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.015
retinal diseaseDOID:567900.015
retinal degenerationDOID:846600.015
eye diseaseDOID:561400.015
eye and adnexa diseaseDOID:149200.015
urinary system diseaseDOID:1800.013
disease of metabolismDOID:001466700.012